BIOTIME INC
SC 13D/A, 1999-05-20
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D
          Under the Securities Exchange Act of 1934 (Amendment No. 6)*


                                  BioTime, Inc.
 ...............................................................................
                                (Name of Issuer)

                           Common Shares, no par value
 ...............................................................................
                         (Title of Class of Securities)

                                    09066L105
 ...............................................................................
                                 (CUSIP Number)

                          Paul Segall and Judith Segall
          935 Pardee Street, Berkeley, California 94710; (510) 845-9535
 ...............................................................................
(Name, Address and Telephone Number of Person Authorized to Receive Notices 
 and Communications)

                                  May 10, 1999
 ...............................................................................
              (Date of Event which Requires Filing this Statement)


If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of ss.ss.240.13d-1(e), 240.13d-1(f), or 240.13d-1(g), check the
following box [ ].

NOTE:  Schedules  filed in paper format shall include a signed original and five
copies of the schedule,  including all exhibits.  See  ss.240.13d-7(b) for other
parties to whom copies are to be sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.


<PAGE>



CUSIP No. 09066L105

         1)       Names of Reporting Persons S.S. or I.R.S. Identification Nos.
                   of Above Persons 
                            Paul Segall

         2)       Check the Appropriate Box if a Member of a Group 
                   (See Instructions)
                           (a) [ ]
                           (b) [ ]
         3)       SEC Use Only

         4)       Source of Funds (See Instructions)
                           PF; OO

         5)       Check if Disclosure of Legal  Proceedings is Required Pursuant
                  to Items 2(d) or 2(e) [ ]

         6)       Citizenship or Place of Organization
                           U.S.A.

                  7)       Sole Voting Power
Number of                        543,245
Shares
Beneficially      8)       Shared Voting Power
Owned by                         0
Each
Reporting         9)       Sole Dispositive Power
Person With                      543,245

                  10)      Shared Dispositive Power
                                 0

         11)      Aggregate Amount Beneficially Owned by Each Reporting Person
                           745,408

         12)      Check if the Aggregate Amount in Row (11) Excludes Certain 
                   Shares (See Instructions)                [ ]

         13)      Percent of Class Represented by Amount in Row (11)
                           6.9%

         14)      Type of Reporting Person (See Instructions)
                           IN

                               Page 2 of 6 Pages
<PAGE>


CUSIP No. 09066L105

         1)       Names of Reporting Persons S.S. or I.R.S. Identification Nos.
                   of Above Persons
                           Judith Segall

         2)       Check the Appropriate Box if a Member of a Group 
                   (See Instructions)
                           (a) [ ]
                           (b) [ ]
         3)       SEC Use Only

         4)       Source of Funds (See Instructions)
                           PF; OO

         5)       Check if Disclosure of Legal  Proceedings is Required Pursuant
                  to Items 2(d) or 2(e) [ ]

         6)       Citizenship or Place of Organization
                           U.S.A.

                  7)       Sole Voting Power
Number of                        202,163
Shares
Beneficially      8)       Shared Voting Power
Owned by                         0
Each
Reporting         9)       Sole Dispositive Power
Person With                      202,163

                  10)      Shared Dispositive Power
                                 0

         11)      Aggregate Amount Beneficially Owned by Each Reporting Person
                           745,408

         12)      Check if the Aggregate Amount in Row (11) Excludes Certain 
                   Shares (See Instructions)    [ ]

         13)      Percent of Class Represented by Amount in Row (11)
                           6.9%

         14)      Type of Reporting Person (See Instructions)
                           IN

                               Page 3 of 6 Pages
<PAGE>



Item 1.  Security and Issuer

         The class of equity securities to which this schedule relates is Common
Shares,  no par value (the  "Common  Shares"),  of BioTime,  Inc.,  a California
corporation (the "Company").  The Company has its principal executive offices at
935 Pardee Street, Berkeley, California 94710.

         This  schedule  is  being  filed  pursuant  to  Section  13(d)  of  the
Securities  Exchange Act of 1934, as amended (the "Exchange  Act") and the rules
and regulations promulgated thereunder.

Item 2.  Identity and Background

(a) The names of the  persons  filing this  schedule  are Paul Segall and Judith
Segall.

(b)      The business address of Paul Segall and Judith Segall is 935 Pardee 
         Street, Berkeley, California 94710.

(c)      Paul Segall is currently the Chairman and Chief Executive Officer of 
         BioTime, Inc., 935 Pardee Street, Berkeley, California 94710.

         Judith Segall is currently the Vice President and Secretary of BioTime,
         Inc.

(d)      Paul Segall and Judith Segall have not been  convicted  during the last
         five years in a criminal  proceeding,  excluding traffic  violations or
         similar misdemeanors.

(e)      Neither Paul Segall nor Judith  Segall has been a party during the last
         five years to any civil roceeding of a judicial or administrative body 
         of competent jurisdiction, and neither of them has, as a result of such
         a  proceeding,  been  subject  to a  judgment,  decree  or final  order
         enjoining future violations of, or prohibiting or mandating  activities
         subject to, federal or state  securities  laws or finding any violation
         with respect to such laws.

(f)      Both Paul Segall and Judith Segall are citizens of the United States of
         America.

Item 3.  Source and Amount of Funds or Other Consideration

         Paul Segall and Judith Segall have each  executed a Customer  Agreement
and Control or Restricted (Rule 144) Stock Borrower's  Agreement  (collectively,
"Customer Agreement") with Donaldson,  Lufkin & Jenrette Securities  Corporation
("DLJ")  pursuant to which they may borrow funds from time time. On or about May
10, 1999, Mr. and Mrs. Segall borrowed $1,133,477.71 from DLJ under the terms of
their Customer  Agreement and used the proceeds to repay certain margin loans to
NationsBank Montgomery Securities.


                               Page 4 of 6 Pages
<PAGE>


         Mr. and Mrs.  Segall have pledged a portion of their  Common  Shares as
collateral for such loans. A copy of the aforesaid  Customer  Agreement is filed
as an Exhibit to this Schedule 13D and is incorporated herein by reference.


Item 7.  Material to Be Filed as Exhibits

(a)    Customer Agreement with Donald, Lufkin & Jenrette Securities Corporation

(b)    Control or Restricted (Rule 144) Stock Borrower's Agreement


                               Page 5 of 6 Pages
<PAGE>


Signature


         After  reasonable  inquiry and to the best of our  knowledge we certify
that the information set forth in the statement is true, complete and correct.

                                                   /s/ Paul Segall
Dated:  May 12, 1999                       ____________________________________
                                                   Paul Segall

                                                   /s/ Judith Segall
Dated:  May 12, 1999                       ____________________________________
                                                   Judith Segall



                               Page 6 of 6 Pages




                          DONALDSON, LUFKIN & JENRETTE
                             Securities Corporation
                    277 Park Avenue, New York, New York 10172


                               CUSTOMER AGREEMENT


         In consideration of your accepting and carrying for the undersigned one
or more accounts, the undersigned hereby consents and agrees that:

APPLICABLE RULES AND REGULATIONS

1. All  transactions for the undersigned  shall be subject to the  constitution,
rules,  regulations,  customs  and  usages of the  exchange  or  market  and its
clearing  house,  if any, where  executed by you or your agents,  including your
subsidiaries and affiliates.


DEFINITION

2. For purposes of this agreement "securities,  commodities and other property,"
as used  herein  shall  include,  but not be limited to money,  securities,  and
commodities  of every kind and nature and all  contracts  and  options  relating
thereto, whether for present or future delivery.

LIEN

3. All securities, commodities and other property now or hereafter held, carried
or maintained by you in your  possession and control for any purpose,  in or for
any of the  accounts of the  undersigned,  now or  hereafter  opened,  including
accounts in which the  undersigned  may have an interest,  shall be subject to a
lien for the  discharge of all the  indebtedness  and other  obligations  of the
undersigned to you, and are to be held by you as security for the payment of any
liability or indebtedness of the undersigned to you in any of said accounts. You
shall have the right to transfer  securities,  commodities and other property so
held by you from or to any other of the accounts of the undersigned  whenever in
your judgment you consider such a transfer  necessary  for your  protection.  In
enforcing your lien, you shall have the discretion to determine which securities
and property are to be sold and which contracts are to be closed.

LIQUIDATION

4. You shall have the right, in accordance with your general policies  regarding
your  margin  maintenance  requirements,  as such may be  modified,  amended  or
supplemented  from  time to time,  or if, in your  discretion  you  consider  it
necessary for your protection to require additional  collateral at an earlier or


                                       1
<PAGE>



later point in time than called for by said  general  policies,  or in the event
that a petition in bankruptcy,  or for  appointment of a received is filed by or
against the undersigned,  or an attachment is levied against the accounts of the
undersigned, or in the event of the death of the undersigned, to sell any or all
securities,  commodities  and other property in the accounts of the  undersigned
with you, whether carried individually or jointly with others, to buy any or all
securities,  commodities and other property which may be short in such accounts,
to cancel any open  orders and to close any or all  outstanding  contracts,  all
without  demand for margin or additional  margin,  notice of sale or purchase or
other notice to  advertisement.  Any such sales or purchases may be made at your
discretion  on any  exchange  or other  market  where such  business  is usually
transacted,  or at public auction or private sale, and you may be the purchasers
for your own account. It being understood that a prior demand, or call, or prior
notice of the time and place of such sale or purchase  shall not be considered a
waiver of your right to sell or buy without demand or notice as herein provided.

PAYMENT OF INDEBTEDNESS UPON DEMAND

5. The  undersigned  shall at all times be liable for the payment upon demand of
any debit  balance  or other  obligations  owing in any of the  accounts  of the
undersigned  with you  and,  the  undersigned  shall  be  liable  to you for any
deficiency  remaining  in any such  accounts  in the  event  of the  liquidation
thereof, in whole or in part, by you or by the undersigned; and, the undersigned
shall make payment of such obligations and indebtedness upon demand.

LIABILITY FOR COSTS OF COLLECTION

6. The reasonable  costs and expenses of collection of the debit balance and any
unpaid  deficiency in the accounts of the undersigned with you,  including,  but
not limited to,  attorney's  fees,  incurred and payable or paid by you shall be
payable to you by the undersigned.

PLEDGE OF SECURITIES, COMMODITIES AND OTHER PROPERTY

7. All  securities,  commodities  and other  property  now or  thereafter  held,
carried or  maintained  by you in your  possession in any of the accounts of the
undersigned  may be  pledged  and  repledged  by you from time to time,  without
notice to the  undersigned,  either  separately  or in common  with  other  such
securities, commodities and other property for any amount due in the accounts of
the undersigned,  or for any greater amount, and you may do so without retaining
to your possession or control for delivery a like amount of similar  securities,
commodities or other property.

MARGIN REQUIREMENTS, CREDIT CHARGES AND CREDIT INVESTIGATION

8. The undersigned will at all times maintain such  securities,  commodities and
other  property in the accounts of the  undersigned  for margin  purposes as you
shall  require  from time to time and the  monthly  debit  balances  or adjusted
balances  in the  accounts  of the  undersigned  with you shall be  charged,  in
accordance with your usual custom, with interest at a rate permitted by the laws


                                       2
<PAGE>



of the State of New York. It is understood  that the interest charge made to the
undersigned's  account  at the  close  of a charge  period  will be added to the
opening balance for the next charge period unless paid.

         You may exchange credit  information about the undersigned with others.
You may request a credit report on the  undersigned  and upon request,  you will
state the name and address of the consumer  reporting  agency that furnished it.
If you extend,  update or renew the undersigned's  credit, you may request a new
credit report without telling the undersigned.

PRESUMPTION OF RECEIPT OF COMMUNICATIONS

9.  Communications  may  be  sent  to the  undersigned  at  the  address  of the
undersigned or at such other address as the  undersigned  may hereafter give you
in  writing,  and all  communications  so  sent,  whether  by  mail,  telegraph,
messenger or  otherwise,  shall be deemed given to the  undersigned  personally,
whether actually received or not.

NO NON-INVESTMENT ADVICE

10. The undersigned  acknowledges that you will not provide the undersigned with
any legal, tax or accounting  advice,  that your employees are not authorized to
give any such advice and that the undersigned  will not solicit or rely upon any
such advice from you or your employees  whether in connection with  transactions
in or for any of the accounts of the undersigned or otherwise.  In making legal,
tax or accounting  decisions with respect to transactions in or for the accounts
of the undersigned or any other matter,  the  undersigned  will consult with and
rely  upon  its own  advisors  and not  you,  and you  shall  have no  liability
therefor.

SCOPE AND TRANSFERABILITY

11. This agreement shall cover  individually and collectively all accounts which
the  undersigned  may open or reopen with you, and shall inure to the benefit of
your successors whether by merger,  consolidation or otherwise, and assigns, and
you may transfer the accounts of the undersigned to your successors and assigns,
and this agreement shall be binding upon the heirs,  executors,  administrators,
successors and assigns of the undersigned.

EXTRAORDINARY EVENTS

12. You shall not be liable for loss caused directly or indirectly by government
restrictions, exchange or market rulings, suspension of trading, war, strikes or
other conditions beyond your control.


                                       3
<PAGE>



REPRESENTATIONS AS TO CAPACITY TO ENTER INTO AGREEMENT

13. The  undersigned,  if an individual,  represents  that the undersigned is of
full age, that unless  otherwise  disclosed to you in writing the undersigned is
not an employee of any  exchange,  or of any  corporation  of which any exchange
owns a majority of the capital stock, or of a member firm or member  corporation
registered on any exchange or of a bank, trust company,  insurance company or of
any corporations,  firm or individual  engaged in the business of dealing either
as a broker or as  principal in  securities,  bills of exchange  acceptances  or
other forms of commercial paper. The undersigned  further represents that no one
except  the  undersigned  has an  interest  in the  account or  accounts  of the
undersigned with you.

JOINT AND SEVERAL LIABILITY

14.  If the  undersigned  shall  consist  of more  than  one  individual,  their
obligations  under this agreement  shall be joint and several.  The  undersigned
have  executed  the  Joint  Account  Agreement  and made the  election  required
therein.  Pursuant to that  agreement,  you may, but are not required to, accept
instructions from either joint party.

OPTION TRANSACTIONS

15. If at any time the  undersigned  shall  enter into any  transaction  for the
purchase or resale of an option contract, the undersigned hereby agrees to abide
by the  rules of any  national  securities  association,  registered  securities
exchange or clearing organization  applicable to the trading of option contracts
and,  acting  alone or in concert,  will not  violate  the  position or exercise
limitation  rules of any such  association or exchange or of the Option Clearing
Corporation or other clearing organization.

SEPARABILITY

16. If any provision or condition of this agreement  shall be held to be invalid
or unenforceable by any court, or regulatory or self-regulatory  agency or body,
such  invalidity  or  unenforceability  shall  attach only to such  provision or
condition.  The validity of the remaining provisions and conditions shall not be
affected  thereby and this agreement shall be carried out as if any such invalid
or unenforceable provision or condition were not contained herein.

HEADINGS ARE DESCRIPTIVE

17. The heading of each provision  hereof is for  descriptive  purposes only and
shall not be deemed to modify or qualify  any of the rights or  obligations  set
forth in each such provision.

ARBITRATION DISCLOSURES

18.      *        ARBITRATION IS FINAL AND BINDING ON THE PARTIES.

                                       4
<PAGE>



         *        THE PARTIES ARE WAIVING THEIR RIGHT TO SEEK REMEDIES IN COURT,
                  INCLUDING THE RIGHT TO JURY TRIAL
         *        PRE-ARBITRATION DISCOVERY IS GENERALLY MORE LIMITED THAN AND 
                  DIFFERENT FROM COURT PROCEEDINGS.
         *        THE  ARBITRATOR'S  AWARD IS NOT REQUIRED TO INCLUDE  FACTUAL 
                  FINDINGS OR LEGAL REASONING AND ANY
                  PARTY'S RIGHT TO APPEAL OR TO SEEK  MODIFICATION OF RULINGS BY
                  THE ARBITRATORS IS STRICTLY LIMITED.
         *        THE PANEL OF ARBITRATORS WILL TYPICALLY INCLUDE A MINORITY OF
                  ARBITRATORS  WHO WERE OR ARE AFFILIATED WITH THE SECURITIES 
                  INDUSTRY.

AGREEMENT TO ARBITRATE CONTROVERSIES

19. IT IS AGREED THAT ANY CONTROVERSY BETWEEN US ARISING OUT OF YOUR BUSINESS OR
THIS AGREEMENT,  SHALL BE SUBMITTED TO ARBITRATION CONDUCTED BEFORE THE NEW YORK
STOCK  EXCHANGE,  INC.  OR ANY OTHER  NATIONAL  SECURITIES  EXCHANGE  ON WHICH A
TRANSACTION  GIVING RISE TO THE CLAIM TOOK PLACE (AND ONLY BEFORE SUCH EXCHANGE)
OR NASD  REGULATION,  INC., AS THE  UNDERSIGNED MAY ELECT AND IN ACCORDANCE WITH
THE RULES OBTAINING OF THE SELECTED ORGANIZATION.  ARBITRATION MUST BE COMMENCED
BY SERVICE UPON THE OTHER PARTY OF A WRITTEN DEMAND FOR ARBITRATION OR A WRITTEN
NOTICE OF INTENTION TO ARBITRATE,  THEREIN ELECTING THE ARBITRATION TRIBUNAL. IN
THE EVENT THE  UNDERSIGNED  DOES NOT MAKE SUCH ELECTION  WITHIN FIVE (5) DAYS OF
SUCH DEMAND OR NOTICE, THEN THE UNDERSIGNED AUTHORIZES YOU TO DO SO ON BEHALF OF
THE UNDERSIGNED.

         NO  PERSON  SHALL  BRING  A  PUTATIVE  OR  CERTIFIED  CLASS  ACTION  TO
ARBITRATION NOR SEEK TO ENFORCE ANY PRE-DISPUTE  ARBITRATION  AGREEMENT  AGAINST
ANY  PERSON WHO HAS  INITIATED  IN COURT A PUTATIVE  CLASS  ACTION;  OR WHO IS A
MEMBER OF A PUTATIVE  CLASS WHO HAS NOT OPTED OUT OF THE CLASS  WITH  RESPECT TO
ANY  CLAIMS  ENCOMPASSED  BY THE  PUTATIVE  CLASS  ACTION  UNTIL:  (i) THE CLASS
CERTIFICATION IS DENIED; OR (ii) THE CLASS IS DECERTIFIED; OR (iii) THE CUSTOMER
IS  EXCLUDED  FROM THE  CLASS BY THE  COURT.  SUCH  FORBEARANCE  TO  ENFORCE  AN
AGREEMENT  TO ARBITRATE  SHALL NOT  CONSTITUTE A WAIVER OF ANY RIGHTS UNDER THIS
AGREEMENT EXCEPT TO THE EXTENT STATED HEREIN.

THE LAWS OF THE STATE OF NEW YORK GOVERN


                                       5
<PAGE>



20.  THIS  AGREEMENT  AND ITS  ENFORCEMENT  SHALL BE GOVERNED BY THE LAWS OF THE
STATE OF NEW YORK WITHOUT GIVING EFFECT TO ITS CONFLICTS OF LAWS PROVISIONS.

LOAN CONSENT

21.  BY SIGNING THIS AGREEMENT, THE UNDERSIGNED ACKNOWLEDGES THAT SECURITIES NOT
FULLY PAID FOR BY THE UNDERSIGNED MAY BE LOANED TO YOU OR LOANED OUT TO OTHERS.

         THIS AGREEMENT CONTAINS A PRE-DISPUTE ARBITRATION CLAUSE IN PARAGRAPHS
18 AND 19 ON THIS PAGE.  I ACKNOWLEDGE RECEIVING A COPY OF THIS AGREEMENT.

                                   SIGNATURES

(If a Corporation, Partnership or Other Entity)               (If Individuals)

                                                       /s/ Paul Segall
- -------------------------------------           ------------------------------
          Name of Entity

                                                ------------------------------
                                                (Second Party, If Joint Account)


By___________________________________

Title__________________________________
                  SEAL

                   DATED_________________ACCOUNT NO.______________________

                                       6




                     CONTROL OR RESTRICTED (RULE 144) STOCK
                              BORROWER'S AGREEMENT



         In consideration  of any margin credit extended by Donaldson,  Lufkin &
Jenrette Securities  Corporation ("DLJ") to the undersigned on 179,665 shares of
the common stock of BioTime,  Inc. owned by the  undersigned  and pledged to DLJ
(the "Shares"), the undersigned agrees, represents and warrants as follows:


         1.  The  Shares  are  fully  paid  for  and  the   undersigned  is  the
unconditional  beneficial  owner of the Shares,  free and clear of any  security
interest,  claim  or  charge.  The  Shares  are  registered  in the  name of the
undersigned,  no other  person or entity has an  interest  in the Shares and the
undersigned has fully right, power and authority to sell,  pledge,  transfer and
deliver the Shares.


         2. The  Shares or any other  such  shares  owned or  controlled  by the
undersigned  (i)  have  not  been  assigned,   transferred,   donated,  pledged,
encumbered  or the  subject of a put or call  option by the  undersigned  or any
other person or entity (ii) will be deposited in the account of the  undersigned
with DLJ in fully  negotiable  form,  and (iii) for the period of the agreement,
will not be sold, assigned,  transferred,  donated,  pledged,  encumbered or the
subject of a put or call option by the undersigned or any other person or entity
without the prior written consent of a principal of DLJ; provided, however, such
requirement shall not apply to sales of the Shares through DLJ, or the pledge of
the Shares to DLJ as provided in the agreement.


         3. All of the Information set forth by the undersigned in the Form 144,
Rule 144 Questionnaire and representation  letter,  copies of which are attached
and made a part hereof,  is accurate and complete and should any change or event
occur  which  would  render  the  information  Inaccurate  or  Incomplete,   the
undersigned will immediately notify DLJ of such change or event.


         4.  The  margin  credit   arrangement   referred  to  herein  shall  be
supplemental  and in addition to all the terms and  conditions  of the  Customer
Agreement between the undersigned and DLJ which the undersigned  acknowledges he
has read, understood, and executed and which remains in full force and effect.


         5. It is understood  that the minimum margin  required to be maintained
by the  undersigned  for the Shares is 40% of the  current  market  value of the
Shares as  determined  on a day by day basis or $3.00 per  share,  whichever  is
greater. It is further understood that such minimum maintenance  requirement may
be changed by DLJ at any time.

                                       1
<PAGE>

         6. Should it become necessary to sell any of the Shares or to satisfy a
margin deficiency, the undersigned agrees fully to cooperate with DLJ, including
the furnishing of information and completion of forms and instruments  necessary
to effect the sale.  In  addition,  DLJ shall be  authorized  to sign a properly
completed Form 144 in the name of and on behalf of the undersigned.  Capitalized
terms that are used herein but not  otherwise  defined  shall have the  meanings
ascribed  to such  terms in Control or  Restricted  (Rule 144) Stock  Borrower's
Agreement between the undersigned and DLJ of even date herewith.


         7. It is agreed  that in the event the  undersigned  fails to satisfy a
margin  deficiency,  DLJ is hereby  authorized  to  liquidate  at it  discretion
sufficient shares of this security held in the undersigned's  account to satisfy
the margin deficiency.


         8. The  undersigned  will not take any  action  that  would  impair the
salability  of the  Shares or omit to take any  action  necessary  to avoid such
impairment.  The  undersigned  further agrees to indemnify and hold harmless DLJ
and its  officers  and  employees  from any loss,  liability,  claim,  damage or
expense,  including  any  legal  expense,  to  which  DLJ and its  officers  and
employees may become the subject as a result of any untrue statement or omission
in any document  furnished to DLJ by the undersigned or breach of this agreement
by the undersigned.


         9. The  failure by DLJ to object to any act or  omission on the part of
the undersigned  which is in  contravention  of any provision of this agreement,
shall not  constitute a waiver of any of the rights of DLJ under this  agreement
or otherwise.


         10. The  undersigned  represents  that he has sufficient  collateral or
cash to meet any margin  calls which might  result form a margin  deficiency  or
from the subsequent  unavailability of Rule 144 and that he will promptly advise
DLJ should he become aware of any  circumstances  indicating that Rule 144 is no
longer available with respect to the shares pledged.


         11. DLJ agrees that the interest rate to be charged  shall be 3.00% 
above the Pershing  Base Lending  Rate, as described in the attached 
"Disclosure Statement."


                                       2
<PAGE>



         12. This  agreement  shall  remain in full force and effect until it is
either (i)  terminated by DLJ, or (ii)  terminated by the  undersigned  with the
consent  of  DLJ.  However,  all  representations,  warranties  and  indemnities
provided by the  undersigned  hereunder  shall survive the  termination  of this
agreement.

                  /s/Paul Segall
                  -------------------------------
                  (Signature)
                  Paul Segall
                  -------------------------------
                  (Name)

                  -------------------------------
                  (Date)

                  -------------------------------
                  (Account Number)


                  Joint Account

                  -------------------------------
                  (Signature)

                  -------------------------------
                  (Name)

                  -------------------------------
                  (Date)


                                       3




                          DONALDSON, LUFKIN & JENRETTE
                             Securities Corporation
                    277 Park Avenue, New York, New York 10172


                               CUSTOMER AGREEMENT


         In consideration of your accepting and carrying for the undersigned one
or more accounts, the undersigned hereby consents and agrees that:

APPLICABLE RULES AND REGULATIONS

1. All  transactions for the undersigned  shall be subject to the  constitution,
rules,  regulations,  customs  and  usages of the  exchange  or  market  and its
clearing  house,  if any, where  executed by you or your agents,  including your
subsidiaries and affiliates.


DEFINITION

2. For purposes of this agreement "securities,  commodities and other property,"
as used  herein  shall  include,  but not be limited to money,  securities,  and
commodities  of every kind and nature and all  contracts  and  options  relating
thereto, whether for present or future delivery.

LIEN

3. All securities, commodities and other property now or hereafter held, carried
or maintained by you in your  possession and control for any purpose,  in or for
any of the  accounts of the  undersigned,  now or  hereafter  opened,  including
accounts in which the  undersigned  may have an interest,  shall be subject to a
lien for the  discharge of all the  indebtedness  and other  obligations  of the
undersigned to you, and are to be held by you as security for the payment of any
liability or indebtedness of the undersigned to you in any of said accounts. You
shall have the right to transfer  securities,  commodities and other property so
held by you from or to any other of the accounts of the undersigned  whenever in
your judgment you consider such a transfer  necessary  for your  protection.  In
enforcing your lien, you shall have the discretion to determine which securities
and property are to be sold and which contracts are to be closed.

LIQUIDATION

4. You shall have the right, in accordance with your general policies  regarding
your  margin  maintenance  requirements,  as such may be  modified,  amended  or
supplemented  from  time to time,  or if, in your  discretion  you  consider  it
necessary for your protection to require additional  collateral at an earlier or


                                       1
<PAGE>



later point in time than called for by said  general  policies,  or in the event
that a petition in bankruptcy,  or for  appointment of a received is filed by or
against the undersigned,  or an attachment is levied against the accounts of the
undersigned, or in the event of the death of the undersigned, to sell any or all
securities,  commodities  and other property in the accounts of the  undersigned
with you, whether carried individually or jointly with others, to buy any or all
securities,  commodities and other property which may be short in such accounts,
to cancel any open  orders and to close any or all  outstanding  contracts,  all
without  demand for margin or additional  margin,  notice of sale or purchase or
other notice to  advertisement.  Any such sales or purchases may be made at your
discretion  on any  exchange  or other  market  where such  business  is usually
transacted,  or at public auction or private sale, and you may be the purchasers
for your own account. It being understood that a prior demand, or call, or prior
notice of the time and place of such sale or purchase  shall not be considered a
waiver of your right to sell or buy without demand or notice as herein provided.

PAYMENT OF INDEBTEDNESS UPON DEMAND

5. The  undersigned  shall at all times be liable for the payment upon demand of
any debit  balance  or other  obligations  owing in any of the  accounts  of the
undersigned  with you  and,  the  undersigned  shall  be  liable  to you for any
deficiency  remaining  in any such  accounts  in the  event  of the  liquidation
thereof, in whole or in part, by you or by the undersigned; and, the undersigned
shall make payment of such obligations and indebtedness upon demand.

LIABILITY FOR COSTS OF COLLECTION

6. The reasonable  costs and expenses of collection of the debit balance and any
unpaid  deficiency in the accounts of the undersigned with you,  including,  but
not limited to,  attorney's  fees,  incurred and payable or paid by you shall be
payable to you by the undersigned.

PLEDGE OF SECURITIES, COMMODITIES AND OTHER PROPERTY

7. All  securities,  commodities  and other  property  now or  thereafter  held,
carried or  maintained  by you in your  possession in any of the accounts of the
undersigned  may be  pledged  and  repledged  by you from time to time,  without
notice to the  undersigned,  either  separately  or in common  with  other  such
securities, commodities and other property for any amount due in the accounts of
the undersigned,  or for any greater amount, and you may do so without retaining
to your possession or control for delivery a like amount of similar  securities,
commodities or other property.

MARGIN REQUIREMENTS, CREDIT CHARGES AND CREDIT INVESTIGATION

8. The undersigned will at all times maintain such  securities,  commodities and
other  property in the accounts of the  undersigned  for margin  purposes as you
shall  require  from time to time and the  monthly  debit  balances  or adjusted
balances  in the  accounts  of the  undersigned  with you shall be  charged,  in
accordance with your usual custom, with interest at a rate permitted by the laws


                                       2
<PAGE>



of the State of New York. It is understood  that the interest charge made to the
undersigned's  account  at the  close  of a charge  period  will be added to the
opening balance for the next charge period unless paid.

         You may exchange credit  information about the undersigned with others.
You may request a credit report on the  undersigned  and upon request,  you will
state the name and address of the consumer  reporting  agency that furnished it.
If you extend,  update or renew the undersigned's  credit, you may request a new
credit report without telling the undersigned.

PRESUMPTION OF RECEIPT OF COMMUNICATIONS

9.  Communications  may  be  sent  to the  undersigned  at  the  address  of the
undersigned or at such other address as the  undersigned  may hereafter give you
in  writing,  and all  communications  so  sent,  whether  by  mail,  telegraph,
messenger or  otherwise,  shall be deemed given to the  undersigned  personally,
whether actually received or not.

NO NON-INVESTMENT ADVICE

10. The undersigned  acknowledges that you will not provide the undersigned with
any legal, tax or accounting  advice,  that your employees are not authorized to
give any such advice and that the undersigned  will not solicit or rely upon any
such advice from you or your employees  whether in connection with  transactions
in or for any of the accounts of the undersigned or otherwise.  In making legal,
tax or accounting  decisions with respect to transactions in or for the accounts
of the undersigned or any other matter,  the  undersigned  will consult with and
rely  upon  its own  advisors  and not  you,  and you  shall  have no  liability
therefor.

SCOPE AND TRANSFERABILITY

11. This agreement shall cover  individually and collectively all accounts which
the  undersigned  may open or reopen with you, and shall inure to the benefit of
your successors whether by merger,  consolidation or otherwise, and assigns, and
you may transfer the accounts of the undersigned to your successors and assigns,
and this agreement shall be binding upon the heirs,  executors,  administrators,
successors and assigns of the undersigned.

EXTRAORDINARY EVENTS

12. You shall not be liable for loss caused directly or indirectly by government
restrictions, exchange or market rulings, suspension of trading, war, strikes or
other conditions beyond your control.


                                       3
<PAGE>



REPRESENTATIONS AS TO CAPACITY TO ENTER INTO AGREEMENT

13. The  undersigned,  if an individual,  represents  that the undersigned is of
full age, that unless  otherwise  disclosed to you in writing the undersigned is
not an employee of any  exchange,  or of any  corporation  of which any exchange
owns a majority of the capital stock, or of a member firm or member  corporation
registered on any exchange or of a bank, trust company,  insurance company or of
any corporations,  firm or individual  engaged in the business of dealing either
as a broker or as  principal in  securities,  bills of exchange  acceptances  or
other forms of commercial paper. The undersigned  further represents that no one
except  the  undersigned  has an  interest  in the  account or  accounts  of the
undersigned with you.

JOINT AND SEVERAL LIABILITY

14.  If the  undersigned  shall  consist  of more  than  one  individual,  their
obligations  under this agreement  shall be joint and several.  The  undersigned
have  executed  the  Joint  Account  Agreement  and made the  election  required
therein.  Pursuant to that  agreement,  you may, but are not required to, accept
instructions from either joint party.

OPTION TRANSACTIONS

15. If at any time the  undersigned  shall  enter into any  transaction  for the
purchase or resale of an option contract, the undersigned hereby agrees to abide
by the  rules of any  national  securities  association,  registered  securities
exchange or clearing organization  applicable to the trading of option contracts
and,  acting  alone or in concert,  will not  violate  the  position or exercise
limitation  rules of any such  association or exchange or of the Option Clearing
Corporation or other clearing organization.

SEPARABILITY

16. If any provision or condition of this agreement  shall be held to be invalid
or unenforceable by any court, or regulatory or self-regulatory  agency or body,
such  invalidity  or  unenforceability  shall  attach only to such  provision or
condition.  The validity of the remaining provisions and conditions shall not be
affected  thereby and this agreement shall be carried out as if any such invalid
or unenforceable provision or condition were not contained herein.

HEADINGS ARE DESCRIPTIVE

17. The heading of each provision  hereof is for  descriptive  purposes only and
shall not be deemed to modify or qualify  any of the rights or  obligations  set
forth in each such provision.

ARBITRATION DISCLOSURES

18.      *        ARBITRATION IS FINAL AND BINDING ON THE PARTIES.

                                       4
<PAGE>



         *        THE PARTIES ARE WAIVING THEIR RIGHT TO SEEK REMEDIES IN COURT,
                  INCLUDING THE RIGHT TO JURY TRIAL
         *        PRE-ARBITRATION DISCOVERY IS GENERALLY MORE LIMITED THAN AND 
                  DIFFERENT FROM COURT PROCEEDINGS.
         *        THE  ARBITRATOR'S  AWARD IS NOT REQUIRED TO INCLUDE  FACTUAL 
                  FINDINGS OR LEGAL REASONING AND ANY
                  PARTY'S RIGHT TO APPEAL OR TO SEEK  MODIFICATION OF RULINGS BY
                  THE ARBITRATORS IS STRICTLY LIMITED.
         *        THE PANEL OF ARBITRATORS WILL TYPICALLY INCLUDE A MINORITY OF
                  ARBITRATORS  WHO WERE OR ARE AFFILIATED WITH THE SECURITIES 
                  INDUSTRY.

AGREEMENT TO ARBITRATE CONTROVERSIES

19. IT IS AGREED THAT ANY CONTROVERSY BETWEEN US ARISING OUT OF YOUR BUSINESS OR
THIS AGREEMENT,  SHALL BE SUBMITTED TO ARBITRATION CONDUCTED BEFORE THE NEW YORK
STOCK  EXCHANGE,  INC.  OR ANY OTHER  NATIONAL  SECURITIES  EXCHANGE  ON WHICH A
TRANSACTION  GIVING RISE TO THE CLAIM TOOK PLACE (AND ONLY BEFORE SUCH EXCHANGE)
OR NASD  REGULATION,  INC., AS THE  UNDERSIGNED MAY ELECT AND IN ACCORDANCE WITH
THE RULES OBTAINING OF THE SELECTED ORGANIZATION.  ARBITRATION MUST BE COMMENCED
BY SERVICE UPON THE OTHER PARTY OF A WRITTEN DEMAND FOR ARBITRATION OR A WRITTEN
NOTICE OF INTENTION TO ARBITRATE,  THEREIN ELECTING THE ARBITRATION TRIBUNAL. IN
THE EVENT THE  UNDERSIGNED  DOES NOT MAKE SUCH ELECTION  WITHIN FIVE (5) DAYS OF
SUCH DEMAND OR NOTICE, THEN THE UNDERSIGNED AUTHORIZES YOU TO DO SO ON BEHALF OF
THE UNDERSIGNED.

         NO  PERSON  SHALL  BRING  A  PUTATIVE  OR  CERTIFIED  CLASS  ACTION  TO
ARBITRATION NOR SEEK TO ENFORCE ANY PRE-DISPUTE  ARBITRATION  AGREEMENT  AGAINST
ANY  PERSON WHO HAS  INITIATED  IN COURT A PUTATIVE  CLASS  ACTION;  OR WHO IS A
MEMBER OF A PUTATIVE  CLASS WHO HAS NOT OPTED OUT OF THE CLASS  WITH  RESPECT TO
ANY  CLAIMS  ENCOMPASSED  BY THE  PUTATIVE  CLASS  ACTION  UNTIL:  (i) THE CLASS
CERTIFICATION IS DENIED; OR (ii) THE CLASS IS DECERTIFIED; OR (iii) THE CUSTOMER
IS  EXCLUDED  FROM THE  CLASS BY THE  COURT.  SUCH  FORBEARANCE  TO  ENFORCE  AN
AGREEMENT  TO ARBITRATE  SHALL NOT  CONSTITUTE A WAIVER OF ANY RIGHTS UNDER THIS
AGREEMENT EXCEPT TO THE EXTENT STATED HEREIN.

THE LAWS OF THE STATE OF NEW YORK GOVERN


                                       5
<PAGE>



20.  THIS  AGREEMENT  AND ITS  ENFORCEMENT  SHALL BE GOVERNED BY THE LAWS OF THE
STATE OF NEW YORK WITHOUT GIVING EFFECT TO ITS CONFLICTS OF LAWS PROVISIONS.

LOAN CONSENT

21.  BY SIGNING THIS AGREEMENT, THE UNDERSIGNED ACKNOWLEDGES THAT SECURITIES NOT
FULLY PAID FOR BY THE UNDERSIGNED MAY BE LOANED TO YOU OR LOANED OUT TO OTHERS.

         THIS AGREEMENT CONTAINS A PRE-DISPUTE ARBITRATION CLAUSE IN PARAGRAPHS
18 AND 19 ON THIS PAGE.  I ACKNOWLEDGE RECEIVING A COPY OF THIS AGREEMENT.

                                   SIGNATURES

(If a Corporation, Partnership or Other Entity)               (If Individuals)

                                                       /s/ Judith Segall
- -------------------------------------           ------------------------------
          Name of Entity

                                                ------------------------------
                                                (Second Party, If Joint Account)


By___________________________________

Title__________________________________
                  SEAL

                   DATED_________________ACCOUNT NO.______________________



                                      6



                     CONTROL OR RESTRICTED (RULE 144) STOCK
                              BORROWER'S AGREEMENT



         In consideration  of any margin credit extended by Donaldson,  Lufkin &
Jenrette Securities  Corporation ("DLJ") to the undersigned on  47,031 shares of
the common stock of BioTime,  Inc. owned by the  undersigned  and pledged to DLJ
(the "Shares"), the undersigned agrees, represents and warrants as follows:


         1.  The  Shares  are  fully  paid  for  and  the   undersigned  is  the
unconditional  beneficial  owner of the Shares,  free and clear of any  security
interest,  claim  or  charge.  The  Shares  are  registered  in the  name of the
undersigned,  no other  person or entity has an  interest  in the Shares and the
undersigned has fully right, power and authority to sell,  pledge,  transfer and
deliver the Shares.


         2. The  Shares or any other  such  shares  owned or  controlled  by the
undersigned  (i)  have  not  been  assigned,   transferred,   donated,  pledged,
encumbered  or the  subject of a put or call  option by the  undersigned  or any
other person or entity (ii) will be deposited in the account of the  undersigned
with DLJ in fully  negotiable  form,  and (iii) for the period of the agreement,
will not be sold, assigned,  transferred,  donated,  pledged,  encumbered or the
subject of a put or call option by the undersigned or any other person or entity
without the prior written consent of a principal of DLJ; provided, however, such
requirement shall not apply to sales of the Shares through DLJ, or the pledge of
the Shares to DLJ as provided in the agreement.


         3. All of the Information set forth by the undersigned in the Form 144,
Rule 144 Questionnaire and representation  letter,  copies of which are attached
and made a part hereof,  is accurate and complete and should any change or event
occur  which  would  render  the  information  Inaccurate  or  Incomplete,   the
undersigned will immediately notify DLJ of such change or event.


         4.  The  margin  credit   arrangement   referred  to  herein  shall  be
supplemental  and in addition to all the terms and  conditions  of the  Customer
Agreement between the undersigned and DLJ which the undersigned  acknowledges he
has read, understood, and executed and which remains in full force and effect.


         5. It is understood  that the minimum margin  required to be maintained
by the  undersigned  for the Shares is 40% of the  current  market  value of the
Shares as  determined  on a day by day basis or $3.00 per  share,  whichever  is
greater. It is further understood that such minimum maintenance  requirement may
be changed by DLJ at any time.

                                       1
<PAGE>

         6. Should it become necessary to sell any of the Shares or to satisfy a
margin deficiency, the undersigned agrees fully to cooperate with DLJ, including
the furnishing of information and completion of forms and instruments  necessary
to effect the sale.  In  addition,  DLJ shall be  authorized  to sign a properly
completed Form 144 in the name of and on behalf of the undersigned.  Capitalized
terms that are used herein but not  otherwise  defined  shall have the  meanings
ascribed  to such  terms in Control or  Restricted  (Rule 144) Stock  Borrower's
Agreement between the undersigned and DLJ of even date herewith.


         7. It is agreed  that in the event the  undersigned  fails to satisfy a
margin  deficiency,  DLJ is hereby  authorized  to  liquidate  at it  discretion
sufficient shares of this security held in the undersigned's  account to satisfy
the margin deficiency.


         8. The  undersigned  will not take any  action  that  would  impair the
salability  of the  Shares or omit to take any  action  necessary  to avoid such
impairment.  The  undersigned  further agrees to indemnify and hold harmless DLJ
and its  officers  and  employees  from any loss,  liability,  claim,  damage or
expense,  including  any  legal  expense,  to  which  DLJ and its  officers  and
employees may become the subject as a result of any untrue statement or omission
in any document  furnished to DLJ by the undersigned or breach of this agreement
by the undersigned.


         9. The  failure by DLJ to object to any act or  omission on the part of
the undersigned  which is in  contravention  of any provision of this agreement,
shall not  constitute a waiver of any of the rights of DLJ under this  agreement
or otherwise.


         10. The  undersigned  represents  that he has sufficient  collateral or
cash to meet any margin  calls which might  result form a margin  deficiency  or
from the subsequent  unavailability of Rule 144 and that he will promptly advise
DLJ should he become aware of any  circumstances  indicating that Rule 144 is no
longer available with respect to the shares pledged.


         11. DLJ agrees that the interest rate to be charged  shall be 3.00% 
above the Pershing  Base Lending  Rate, as described in the attached 
"Disclosure Statement."


                                       2
<PAGE>



         12. This  agreement  shall  remain in full force and effect until it is
either (i)  terminated by DLJ, or (ii)  terminated by the  undersigned  with the
consent  of  DLJ.  However,  all  representations,  warranties  and  indemnities
provided by the  undersigned  hereunder  shall survive the  termination  of this
agreement.

                  /s/Judith Segall
                  -------------------------------
                  (Signature)
                  Judith Segall
                  -------------------------------
                  (Name)

                  -------------------------------
                  (Date)

                  -------------------------------
                  (Account Number)


                  Joint Account

                  -------------------------------
                  (Signature)

                  -------------------------------
                  (Name)

                  -------------------------------
                  (Date)


                                       3



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