BIOTIME INC
4, 1999-04-09
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
FORM 4
[]Check this box if no longer
  subject to Section 16. Form 4 or                 OMB APPROVAL                 
  Form 5 obligations may continue.                 OMB Number:    3235-0287     
  See Instruction 1(b).                            Expires: September 30, 1998  
                                                   Estimated average burden     
                                                   hours per response.......0.5 
(Print or Type Responses)
 
                 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
                                                                                
           Filed pursuant to Section 16(a) of the Securities Exchange
      Act of 1934, Section 17(a) of the Public Utility Holding Company Act
          of 1935 or Section 30(f)of the Investment Company Act of 1940
<TABLE>
<CAPTION>
<S>                                            <C>                         <C>                <C>

1. Name and Address of Reporting Person*        2. Issuer Name and Ticker or Trading Symbol   6. Relationship of Reporting Person(s)
                                                   BioTime, Inc. (BTIM)                          to Issuer (Check all applicable)
Barkin          Ronald         S.                                                               __X__ Director     _____ 10% Owner
(Last)          (First)      (Middle)           3.  IRS or Social Security  4.  Statement for   __X__ Officer(give _____ Other
                                                    Number of Reporting         Month/Year            title below)   specify below)
                                                    Person (Voluntary)            3/99                  President
                                                                                                    -------------------  
935 Pardee Street                                                                                
(Street)                                        5.  If Amendment,                             7.  Individual or Joint/Group Filing 
                                                    Date of Original                              (Check Applicable Line)
                                                      (Month/Year)                             _X_Form filed by One Reporting Person
Berkeley      CA           94710                                                               ___Form filed by More than One
(City)      (State)        (Zip)                                                                   Reporting Person
</TABLE>

<TABLE>
<CAPTION>

 Table 1 -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned



<S>                     <C>            <C>              <C>                        <C>              <C>            <C>
1.  Title of Security   2.  Trans-     3.  Trans-       4. Securities Acquired(A)  5. Amount of     6.  Owner-      7. Nature of
     (Instr. 3)             action         action          or Disposed of (D)         Securities        ship           Indirect
                            Date           Code           (Instr. 3, 4 and 5)         Beneficially      Form:          Beneficial
                                          (Instr. 8)                                  Owned at          Direct         Ownership
                                                                                      End of Month      (D) or
                            (Month/                                                                     Indirect
                              Day/                                                    Inst. 3 and 4)    (I)                   
                             Year)                                 (A)or
                                                          Amount   (D)       Price                     (Instr. 4)      (Instr. 4)
 ----------------------------------------------------------------------------------------------------------------------------------
  Common Shares,            3/9/99           X            2,750     A        $9.75       192,761*          D
   no par value
- -----------------------------------------------------------------------------------------------------------------------------------
 
- -----------------------------------------------------------------------------------------------------------------------------------
  
- -----------------------------------------------------------------------------------------------------------------------------------

<FN>
Reminder:   Report  on  a  separate  line  for  each  class  of  securities
beneficially  owned directly or  indirectly. 
*If the form is filed by more than one reporting person,see Instruction 4(b)(v).

                                                                          (Over)
                                                                  SEC 1471(7-96)
</FN>
</TABLE>

<PAGE>
FORM 4 (continued)
<TABLE>
<CAPTION>

  Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
         (e.g., puts, calls, warrants, options, convertible securities)


<S>                              <C>            <C>          <C>             <C>                     <C>
1. Title of Derivative Security  2. Conver-     3. Trans-   4. Trans-       5. Number of Deriv-       6. Date Exer-      
       (Instr. 3)                   sion or        action      action          ative Securities Ac-      cisable and     
                                    Exercise       Date        Code            quired (A) or Dis-        Expiration      
                                    Price of                  (Instr. 8)       posed of (D)              Date            
                                    Deri-         (Month/                     (Instr. 3, 4 and 5)       (Month/Day/      
                                    vative          Day/                                                 Year)           
                                    Security       Year)                                                                 
                                                                                                      Date       Expir-  
                                                                                (A)        (D)        Exer-      ation   
                                                                                                     cisable     Date    
                                                                                                                         
- -----------------------------------------------------------------------------------------------------------------------------------
Common Shares Subscription Rights    $9.75         3/9/99          X                       55,011     2/12/99     3/9/99
- -----------------------------------------------------------------------------------------------------------------------------------

- -----------------------------------------------------------------------------------------------------------------------------------
</TABLE>
<TABLE>
<CAPTION>
<S>                   <C>           <C>           <C>           <C>            
7. Title and Amount   8. Price      9. Number     10.Owner-     11. Nature     
   of Underlying         of            of deriv-     ship           of         
   Securities            Deriv-        ative         Form of        Indirect   
  (Instr. 3 and 4)       ative         Secur-        Deriv-         Benefi-    
                         Secur-        ities         ative          cial       
                         ity           Bene-         Security:      Owner-     
           Amount or     (Instr.       ficially      Direct         ship       
 Title     Number of       5)          Owned        (D)or         (Instr.4) 
           Shares                      at End        Indirect
                                       of Month     (I)
                                      (Instr. 4)    (Instr. 4)
- -------------------------------------------------------------------------------
Common      2,750          N/A            0            D
Shares
- -------------------------------------------------------------------------------

================================================================================
<FN>
Explanation of Responses:

Mr. Barkin acquired 2,750 shares through the exercise of 55,011 subscription 
rights. The subscription rights were distributed on a pro rata basis to all 
BioTime shareholders.

*includes 135,000 shares that may be purchased through the exercise of stock
options.

** Intentional  misstatements or omissions of facts constitute  Federal Criminal
Violations. See 18 U.S.C.  1001 and 15 U.S.C.  78ff(a).

Note: File three copies of this Form, one of which must be manually  signed.  If
space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information  contained
in this form are not  required to respond  unless the form  displays a valid OMB
Number.
</FN>
</TABLE>


  /s/Ronald S. Barkin                                April 6, 1999
- --------------------------------                 ----------------------
**Signature of Reporting Person                          Date          






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