AETNA SERIES FUND INC
497, 2000-12-14
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                             AETNA SERIES FUND, INC.


                       Supplement dated December 14, 2000

THE INFORMATION BELOW SUPPLEMENTS THE INFORMATION CONTAINED IN THE AETNA SERIES
FUND, INC. CLASS A, B AND C PROSPECTUS DATED SEPTEMBER 28, 2000 AND CLASS I
PROSPECTUS DATED MARCH 1, 2000, THE BROKERAGE CASH RESERVES PROSPECTUS DATED
MARCH 1, 2000, AND THE AETNA INDEX PLUS PROTECTION FUND PROSPECTUS DATED
SEPTEMBER 28, 2000. THIS SUPPLEMENT SHOULD BE READ WITH EACH PROSPECTUS AND THE
SUPPLEMENT DATED SEPTEMBER 28, 2000 TO THE CLASS I PROSPECTUS. THIS SUPPLEMENT
SUPERSEDES THE PREVIOUSLY ISSUED SUPPLEMENT TO THE BROKERAGE CASH RESERVES
PROSPECTUS.

On December 13, 2000, Aetna Inc., the indirect parent company of Aeltus
Investment Management, Inc. (Aeltus), each Fund's investment adviser, and Aeltus
Capital, Inc. (ACI), each Fund's principal underwriter, sold its financial
services and international businesses, including Aeltus and ACI, to ING Groep
N.V. (ING). ING is a global financial institution active in the fields of
insurance, banking, and asset management in more than 65 countries, with almost
100,000 employees.

Under the provisions of the Funds' investment advisory agreements and, in the
case of Aetna Technology Fund, the subadvisory agreement, those agreements may
be deemed to have terminated automatically at the time of the closing of the
transaction. As a result, the Board of Directors and the shareholders of the
Funds approved new advisory agreements for the Funds and a new subadvisory
agreement for Aetna Technology Fund, each of which took effect immediately after
the closing of the transaction. Because the transaction also may have caused the
termination of the underwriting agreement with ACI, the Board approved a new
underwriting agreement to take effect immediately after the closing of the
transaction. Each agreement is effective for an initial term ending on December
31, 2001.

<PAGE>

                             AETNA SERIES FUND, INC.


                       Supplement dated December 14, 2000

THE INFORMATION BELOW SUPPLEMENTS THE INFORMATION CONTAINED IN THE STATEMENTS OF
ADDITIONAL INFORMATION ("STATEMENTS") FOR AETNA SERIES FUND, INC. CLASS A, B, C
AND I DATED SEPTEMBER 28, 2000, BROKERAGE CASH RESERVES DATED JUNE 30, 2000, AND
AETNA INDEX PLUS PROTECTION FUND DATED SEPTEMBER 28, 2000. THIS SUPPLEMENT
SHOULD BE READ WITH EACH STATEMENT AND ANY PREVIOUSLY ISSUED SUPPLEMENT.

On December 13, 2000, Aetna Inc., the indirect parent company of Aeltus
Investment Management, Inc. (Aeltus), each Fund's investment adviser, and Aeltus
Capital, Inc. (ACI), each Fund's principal underwriter, sold its financial
services and international businesses, including Aeltus and ACI, to ING Groep
N.V. (ING). ING is a global financial institution active in the fields of
insurance, banking, and asset management in more than 65 countries, with almost
100,000 employees.

Under the provisions of the Funds' investment advisory agreements and, in the
case of Aetna Technology Fund, the subadvisory agreement, those agreements may
be deemed to have terminated automatically at the time of the closing of the
transaction. As a result, the Board of Directors and the shareholders of the
Funds approved new advisory agreements for the Funds and a new subadvisory
agreement for Aetna Technology Fund, each of which took effect immediately after
the closing of the transaction. Because the transaction also may have caused the
termination of the underwriting agreement with ACI, the Board approved a new
underwriting agreement to take effect immediately after the closing of the
transaction. Each agreement is effective for an initial term ending on December
31, 2001.




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