SEPRACOR INC /DE/
SC 13D/A, 1996-10-29
LABORATORY ANALYTICAL INSTRUMENTS
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                                                        CONFORMED COPY


                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                 SCHEDULE 13D

                   Under the Securities Exchange Act of 1934

                                Amendment No. 2

                                  Sepracor Inc.
                                (Name of Issuer)

                      Common Stock, par value $.10 per share
                         (Title of Class of Securities)

                                     817315 10 4
                                    (CUSIP Number)

                                 OFD Partners, L.P.
                               c/o SHB Holdings, L.L.C.
                           153 East 53rd Street, 43rd Floor    
                               New York, New York  10022
                                   (212) 292-6000
             (Name, Address and Telephone Number of Person Authorized 
                      to Receive Notices and Communications)

                               October 28, 1996
                (Date of Event which Requires Filing of this Statement)

               If the filing person has previously filed a statement
     on Schedule 13G to report the acquisition which is the subject of
     this Schedule 13D, and is filing this schedule because of Rule
     13d-1(b)(3) or (4), check the following box ( ).

               Check the following box if a fee is being paid with the
     statement ( ). (A fee is not required only if the reporting
     person:  (1) has a previous statement on file for reporting
     beneficial ownership of more than five percent of the class of
     securities described in Item 1; and 2 has filed
     no amendment subsequent thereto reporting beneficial ownership
     of five percent or less of such class.)  (See Rule 13D-7.)
               NOTE:  Six copies of this statement, including all
     exhibits, should be filed with the Commission.  See Rule 13d-1(a)
     for other parties to whom copies are to be sent.



                                     13D
      CUSIP NO. 817315 10 4           

        1   NAME OF REPORTING PERSON
            S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

            OFD Partners, L.P.
            13-3766719

        2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                       (a) ( )       
                                                       (b) ( )       

        3   SEC USE ONLY

        4   SOURCE OF FUNDS*
            WC

        5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
            PURSUANT TO ITEMS 2(d) or 2(e)                        ( )

        6   CITIZENSHIP OR PLACE OF ORGANIZATION

            Delaware

                                   7    SOLE VOTING POWER
                                            1,223,575
           NUMBER OF
             SHARES                8    SHARED VOTING POWER
          BENEFICIALLY                        -0-
            OWNED BY  
             EACH                  9    SOLE DISPOSITIVE POWER 
           REPORTING                       1,223,575
              PERSON
              WITH                10    SHARED DISPOSITIVE POWER
                                              -0-

       11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

            1,223,575

       12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*        ( )    

       13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

            4.5%

       14   TYPE OF REPORTING PERSON*
            PN



          The Schedule 13D filed on October 10, 1994 and amended
          and restated in its entirety on October 13, 1995 is
          hereby further amended as follows:

          Item 5 is hereby amended to read as follows:

          ITEM 5.   INTEREST IN SECURITIES OF ISSUER.

               (a)  As of the date of this Statement, OFD
          beneficially owns 1,223,575 shares of Common Stock, which
          is represented by 1,178,575 shares of Common Stock and
          45,000 Warrants.  As the Preferred Stock was converted in
          1995 at the time of a call by the Company, OFD holds no
          shares of Preferred Stock.  Based on the 27,069,745
          shares of Common Stock reported outstanding (as of August
          15, 1996) in the Issuer's Quarterly Report on Form 10-Q
          for the quarterly period ended June 30, 1996, OFD
          beneficially owns approximately 4.5% of the outstanding
          shares of Common Stock.

               (b)  OFD has the sole power to vote and dispose of
          all of the shares of the Common Stock and Warrants
          beneficially owned by it.

               (c)  Within the past 60 days, OFD has effected the
          following sales of the Common Stock in open market
          transactions:

          DATE      SHARES    PRICE     TOTAL

          10/10/96  35,000    $15.375   $538,125
          10/17/96  20,000    $15.5625  $311,250
          10/17/96  25,000    $15.75    $393,750
          10/17/96  85,000    $15.875   $1,349,375
          10/17/96  10,000    $16.00    $160,000
          10/17/96  20,000    $17.00    $340,000
          10/17/96  20,000    $16.75    $335,000
          10/17/96  35,000    $16.75    $586,250
          10/28/96  75,000    $15.50    $1,162,500
          10/28/96  15,000    $15.625   $234,375
          10/28/96  45,000    $15.50    $697,500
          10/29/96  25,200    $15.50    $390,600

               (d)  Not applicable.

               (e)  OFD ceased to be the beneficial holder of five
          percent or more of the Common Stock on October 28, 1996. 
          OFD no longer has any filing obligation under Section
          13(d) with respect to the Common Stock.


                                   SIGNATURE

               After reasonable inquiry and to the best of my
          knowledge and belief, I certify that the information set
          forth in this Statement is true, complete and correct.

          Dated:   October 29, 1996

                                        OFD PARTNERS, L.P.
                                        BY SHB HOLDINGS, L.L.C., 
                                          GENERAL PARTNER

                                        By:   /s/ Mark A. Beaudoin 
                                             ________________________
                                             Mark A. Beaudoin, Member



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