NEOSE TECHNOLOGIES INC
SC 13G/A, 1998-02-13
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                   ------------------------------------------



                                 SCHEDULE 13G/A
                    Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*
                   ------------------------------------------



                            Neose Technologies, Inc.
                    -----------------------------------------
                                 Name of Issuer


                     Common Stock, par value $.01 per share
                   ------------------------------------------
                         (Title of Class of Securities)


                                   640522 10 8
                                   -----------
                                  CUSIP Number


         *The  remainder  of this cover page shall be filled out for a reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.

         The information  required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise  subject to the  liabilities of that section of
the Act but shall be subject to all other  provisions of the Act  (however,  see
the Notes to Schedule 13G).


                                        1

<PAGE>

                                  SCHEDULE 13G

CUSIP No.   640522 10 8
- --------------------------------------------------------------------------------
1)       NAME OF REPORTING PERSON
         S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
         Lindsay A. Rosenwald, M.D.
- --------------------------------------------------------------------------------
2)       CHECK THE APPROPRIATE BOX IF MEMBER OF A GROUP   (a)  [ ]   (b)   [ ] 

- --------------------------------------------------------------------------------
3)       SEC USE ONLY

- --------------------------------------------------------------------------------
4)       CITIZENSHIP OR PLACE OF ORGANIZATION
         United States

- --------------------------------------------------------------------------------
                           5)       SOLE VOTING POWER
                                    473,673 /1/
         NUMBER             ----------------------------------------------------
         OF                6)       SHARED VOTING POWER
         SHARES                     32,000 /2/
         BENEFICIALLY       ----------------------------------------------------
         OWNED BY          7)       SOLE DISPOSITIVE POWER
         EACH                       473,673 /1/
         REPORTING          ----------------------------------------------------
         PERSON            8)       SHARED DISPOSITIVE POWER
         WITH                       32,000 /2/
                            ----------------------------------------------------
9)       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         505,673 /1/

- --------------------------------------------------------------------------------
10)      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
         SHARES                     [X]

- --------------------------------------------------------------------------------
11)      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
         5.3%

- --------------------------------------------------------------------------------
12)      TYPE OF REPORTING PERSON
         IN

- --------------------------------------------------------------------------------

- --------

1    Includes  non-qualified  stock  options in the  amount of 3,333  shares and
     1,423 shares granted to Dr. Rosenwald on 6/19/97 and 1/2/98 respectively.

2    Excludes (i) 75,624  shares of Common Stock owned by Dr.  Rosenwald's  wife
     and (ii)  30,250  shares of Common  Stock held by Dr.  Rosenwald's  wife as
     custodian for Dr. Rosenwald's children, as to which Dr. Rosenwald disclaims
     beneficial ownership.

                                        2

<PAGE>

Item 1.

         (a)    Name of Issuer:

                Neose Technologies, Inc. (the "Company")

         (b)    Address of Issuer's Principal Executive Offices:

                102 Witmer Road
                Horsham, PA 19044

Item 2.

         (a)    Name of Person Filing:

                Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald")

         (b)    Address of Principal Business Office or, if None, Residence:

                787 Seventh Avenue, 48th Floor
                New York, N.Y.  10019

         (c)    Citizen:

                Dr. Rosenwald is a citizen of the United States.

         (d)    Title of Class of Securities:

                Common Stock, $0.01 par value ("shares").

         (e)    CUSIP#:

                640522 10 8

Item 3.

                Not applicable.


Item 4.         Ownership:

                For information concerning the ownership of Common Stock of the
                Company by Dr. Rosenwald, see Items 5 through 9 and 11 of the 
                cover

                                              3

<PAGE>


                page to this schedule 13G and footnotes thereto.

Item 5.         Ownership of Five Percent or Less of a Class:

                Not applicable.

Item 6.         Ownership of More than Five Percent on Behalf of Another Person:

                Not applicable.

Item 7.         Identification and Classification of the Subsidiary Which 
                Acquired the Security Being Reported On By the Parent 
                Holding Company:

                Not applicable.

Item 8.         Identification and Classification of Members of the Group:

                Not applicable.

Item 9.         Notice of Dissolution of Group:

                Not applicable.

Item 10.        Certification:

                Not applicable.


                                    SIGNATURE

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.


Dated:  February 12, 1998
        New York, New York

                                            /s/ Lindsay A. Rosenwald, M.D.
                                            ------------------------------
                                            Lindsay A. Rosenwald, M.D.


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