INSURED MUNICIPALS INCOME TRUST 108TH INSURED MULTI SERIES, 497J, 1997-09-29

INSURED MUNICIPALS INCOME TRUST 108TH INSURED MULTI SERIES
497J, 1997-09-29

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<PAGE>
 
                              September 29, 1997



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549-1004

Attn: Filing Desk - Stop 1-4

     Re:  Insured Municipals Income Trust, 108th Insured Multi-Series
          File No. 33-42371  CIK #878491

Ladies/Gentlemen:

     In accordance with the provisions of Rule 497(j) of Regulation C under the 
Securities Act of 1933 (the "Securities Act") this letter serves to certify that
the most recent amendment to the Post-Effective of the subject Registration 
Statement on Form S-6 for the above captioned Trust does not differ from that 
which would have been filed pursuant to Rule 497(b) of the Securities Act.  
Amendment No. 6 to the Post-Effective, which was the most recent amendment to 
the Post-Effective of the Registration Statement, was filed electronically with 
the Commission on September 24, 1997.

                              Very truly yours,



                              Van Kampen American Capital
                               Distributors, Inc.