HUMAN PHEROMONE SCIENCES INC
8-K, 1999-09-30
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                           -------------------------


                                    FORM 8-K

                                 CURRENT REPORT
                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

Date of Report (Date of Earliest Event Reported):  September 29, 1999

                         HUMAN PHEROMONE SCIENCES, INC.
- --------------------------------------------------------------------------------
             (Exact name of Registrant as specified in its charter)


        CALIFORNIA                  0-23544                  94-3107202
- --------------------------------------------------------------------------------
(State or other jurisdiction      (Commission               (IRS Employer
     of incorporation)            File Number)            Identification No.)


          4034 CLIPPER COURT, FREMONT, CALIFORNIA         94538
- --------------------------------------------------------------------------------
         (Address of principal executive offices)      (Zip code)

Registrant's telephone number, including area code:  (510) 226-6874
                                                     ---------------------------

- --------------------------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)


<PAGE>


                    INFORMATION TO BE INCLUDED IN THE REPORT

ITEM 4.  CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANTS

         Ernst &  Young  LLP  resigned  as  auditors  of the  Company  effective
         September  28, 1999.  The reports of Ernst & Young LLP on the Company's
         financial  statements  for the past two fiscal years did not contain an
         adverse  opinion or a disclaimer  of opinion and were not  qualified or
         modified as to uncertainty,  audit scope, or accounting principles. The
         Audit  Committee  of the  Board of  Directors  has not yet  approved  a
         successor auditor.

         In connection with the audits of the Company's financial statements for
         each of the two  fiscal  years  ended  December  31,  1998,  and in the
         subsequent  interim  period  through  the date  hereof,  there  were no
         disagreements  with  Ernst & Young  LLP on any  matters  of  accounting
         principles or practices,  financial statement  disclosure,  or auditing
         scope and  procedures  which,  if not resolved to the  satisfaction  of
         Ernst & Young LLP would have caused Ernst & Young LLP to make reference
         to the matter in their report.  The Company has requested Ernst & Young
         LLP to furnish it a letter addressed to the Commission  stating whether
         it  agrees  with the above  statements.  A copy of that  letter,  dated
         September 29, 1999, is filed as Exhibit 7.1 to this Form 8-K.


Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits.

         Exhibit 7.1 - Letter from Ernst & Young LLP pursuant to Item  304(a)(3)
of Regulation S-K.


                                      -2-


<PAGE>


                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                  HUMAN PHEROMONE SCIENCES, INC.



Date:  September 29, 1999         By: /s/ William P. Horgan
                                      ------------------------------------------
                                      William P. Horgan, Chief Executive Officer


                                      -3-



Exhibit 7.1




September 29, 1999



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC 20549

Gentlemen:

We have read  Item 4 of Form 8-K dated  September  29,  1999 of Human  Pheromone
Sciences,  Inc. and are in agreement with the statements  contained in the first
and second paragraphs on page 2 therein.

                                                Very truly yours,

                                                /s/ Ernst & Young LLP



San Francisco, California




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