EMBREX INC/NC
10-K, 1998-03-30
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                    FORM 10-K
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT
                                     OF 1934

  For the fiscal year ended December 31, 1997 Commission file number 000-19495

                                   ----------

                                  Embrex, Inc.
             (Exact name of registrant as specified in its charter)

         North Carolina                                         56-1469825
  (State or other jurisdiction                               (I.R.S. Employer
of incorporation or organization)                         Identification Number)

1035 Swabia Court, Durham, North Carolina                         27703
 (Address of principal executive offices)                       (Zip Code)

                                 (919) 941-5185
              (Registrant's telephone number, including area code)

        Securities registered pursuant to Section 12(b) of the Act: None

           Securities registered pursuant to Section 12(g) of the Act:
      Common Stock, $.01 Par Value Per Share (and Rights Attached Thereto)
                                (Title of class)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days. Yes _X_  No ___

Indicate by check mark if disclosure of delinquent  filers  pursuant to Item 405
of Regulation  S-K is not contained  herein,  and will not be contained,  to the
best of registrant's  knowledge,  in definitive proxy or information  statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. |_|

As of February 27, 1998, the aggregate  market value of the voting stock held by
non-affiliates  was $43.9  million based on a price per common share of $5.50 at
the close of business on that date.

As of February 27, 1998, there were 8,224,046 shares of the registrant's  common
stock outstanding.

                       DOCUMENTS INCORPORATED BY REFERENCE

     Document                                                 Where Incorporated

     Proxy  Statement  with  respect to the Annual            Part III
     Meeting of Shareholders to be held on May 21,
     1998,  to be filed  with the  Securities  and
     Exchange Commission


<PAGE>


                                      INDEX

                                                                            PAGE
                                                                            ----

PART I

   ITEM 1.   BUSINESS.......................................................

   ITEM 2.   PROPERTIES.....................................................

   ITEM 3.   LEGAL PROCEEDINGS..............................................

   ITEM 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS............

PART II

   ITEM 5.   MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED
             STOCKHOLDER MATTERS............................................

   ITEM 6.   SELECTED FINANCIAL DATA........................................

   ITEM 7.   MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
             CONDITION AND RESULTS OF OPERATIONS............................

   ITEM 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA....................

   ITEM 9.   CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON
             ACCOUNTING AND FINANCIAL DISCLOSURE............................

PART III

   ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT..............

   ITEM 11. EXECUTIVE COMPENSATION..........................................

   ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
            MANAGEMENT......................................................

   ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS..................

PART IV

   ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS
            ON FORM 8-K.....................................................

SIGNATURES..................................................................



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<PAGE>


                                     PART I

ITEM 1. BUSINESS

GENERAL

Embrex,  Inc.  ("Embrex"  or the  "Company")  develops  and  markets  biological
delivery  technology and biological  products to increase the  productivity  and
profitability  of the global poultry  industry.  The Company was incorporated in
1985 in North Carolina.

Embrex has developed and commercialized the INOVOJECT(R)  system, a proprietary,
automated  in-the-egg injection system which can inoculate 20,000 to 50,000 eggs
per hour and  eliminates  the need for manual,  post-hatch  injection of certain
vaccines.  The  INOVOJECT(R)  system is  designed to inject  vaccines  and other
compounds in precisely calibrated volumes into targeted  compartments within the
egg. Embrex markets the  INOVOJECT(R)  system to commercial  poultry  producers,
charging a fee for each egg injected.

In addition to the  INOVOJECT(R)  system,  Embrex has developed and is marketing
its Viral Neutralizing Factor ("VNF(R)") antibody,  useful in the development of
certain  avian  vaccines.  The  Company  also  has  developed  and is  marketing
Bursaplex(TM),  a VNF(R)-based  vaccine for protection  against avian Infectious
Bursal  Disease  ("IBD").  Embrex also is developing  various other  proprietary
pharmaceutical  and  biological  products to improve  bird  health,  reduce bird
production  costs and provide other economic  benefits to the poultry  industry.
These compounds include vaccines,  immune enhancers,  performance  modifiers and
genetic  materials  designed to increase  poultry  productivity and health while
reducing costs.  These products are in various stages of  development,  and some
are being  developed  in  collaboration  with major drug  companies,  the United
States Department of Agriculture (the "USDA"),  and several leading universities
in the  field of  avian  science.  These  compounds  are  being  designed  to be
delivered through the INOVOJECT(R) system, and some may also be administered via
post-hatch injection.

EXISTING PRODUCTS

Patented Egg Injection System (INOVOJECT(R))

Embrex has developed and  commercialized  a  proprietary,  automated  in-the-egg
injection  system  which  can  inoculate  20,000  to  50,000  eggs  per hour and
eliminates the need for manual,  post-hatch injection of certain vaccines.  This
proprietary  system,  called  INOVOJECT(R),  is designed to inject  vaccines and
other  compounds in precisely  calibrated  volumes  into  targeted  compartments
within the egg.  Embrex markets the  INOVOJECT(R)  system to commercial  poultry
producers, charging a fee for each egg injected.

In 1997, the Company converted a number of hatcheries to the INOVOJECT(R) system
and continued  operations of INOVOJECT(R)  systems in hatcheries converted prior
to 1997.  As a result,  at December 31, 1997,  Embrex had over 300  INOVOJECT(R)
systems  installed in the United  States  ("U.S.") and Canada,  as compared with
over 250 at year end 1996. The Company  estimates that its  INOVOJECT(R)  system
inoculates in excess of 80% of all eggs  produced for the North America  broiler
poultry market and,  therefore,  expects only modest INOVOJECT(R) system revenue
growth in this market.

During 1997, the Company also placed a number of INOVOJECT(R)  systems for trial
and on  contract  at  locations  outside  the U.S.  and  Canada.  The  Company's
expansion outside the U.S. and Canada has been focused initially on Europe,  the
Middle East,  Africa and,  during the second half of 1997, on Asia. At year end,
the Company had INOVOJECT(R)  systems either installed or on trial in the United
Kingdom,  Ireland,  France,  Spain, the Netherlands,  Belgium,  Italy, the Czech
Republic,  Israel,  Egypt,  South  Africa,  Turkey,  Australia,  South Korea and
Thailand.  Overall,  the placement of INOVOJECT(R)  systems outside the U.S. and
Canada  is  dependent  on market  acceptance  of  various  in ovo ("in the egg")
vaccines  and  obtaining  regulatory  approval  of these  vaccines  in  numerous
countries.

Certain poultry  diseases are more prevalent in some geographic  regions than in
others. For example,  Marek's disease, for which the INOVOJECT(R) system is used
in the U.S.,  is not as  widespread  in Europe as in North  America.  Similarly,
Infectious  Bursal  Disease or IBD (also known as Gumboro  disease) is prevalent
both in the United States and in Northern



                                       3
<PAGE>


Europe and Asia.  The Company  expects  that primary  usage of its  INOVOJECT(R)
systems will vary by geographic region according to the prevailing  diseases and
regulatory  approval of vaccines for in ovo delivery. 

Viral Neutralizing Factor (VNF(R))

Embrex has developed and commercialized a Viral  Neutralizing  Factor technology
which permits  single-dose  immunization  of the avian embryo  effective for the
life of the bird.  By  combining  VNF(R),  an  antibody,  with a vaccine  virus,
immunization is provided in a single step,  reducing or eliminating  many of the
multiple  vaccinations  carried out in the  industry.  VNF(R) can  neutralize  a
virulent  vaccine  virus without  impairing  the virus'  ability to stimulate an
immune response.  By using VNF(R) in this manner, the virulent vaccine virus can
be made  into a safe and  effective  vaccine  which  can be used in ovo or after
hatching.

The VNF(R) technology is the subject of two issued U.S. patents,  a pending U.S.
patent application, and several foreign patents and foreign patent applications.
The U.S.  patents  are  owned by the  University  of  Arkansas  and  exclusively
licensed to Embrex on a royalty  basis for the life of the patents.  Embrex also
is researching application of VNF(R) for other avian disease vaccines, including
Newcastle's  disease and infectious  bronchitis,  although there is no assurance
such research will result in product opportunities.

To date,  the  Company's  research  efforts with its VNF(R)  compound  have been
focused on avian  uses.  Based on initial  experimental  data,  the  Company now
believes  that the potential  exists for VNF(R) to be used in several  non-avian
species.  The  Company  is  in  the  early  stages  of  exploring  collaborative
relationships  with other  companies for the development and licensing of VNF(R)
for non-avian uses. Embrex has not initiated any regulatory  approval  processes
with respect to non-avian  uses of VNF(R),  nor is there any assurance  that its
efforts in this area will result in products or collaborative agreements. During
1997,  the  Company  obtained  a patent  for the use of VNF(R)  vaccines  in all
non-primate mammals.

Infectious Bursal Disease (IBD) Vaccines

VNF(R) is  especially  useful in vaccines  against  avian IBD,  which  weakens a
bird's immune system. Birds infected by IBD typically exhibit poor growth or can
succumb to other diseases because of a compromised  immune system.  This disease
is  widespread  in the U.S.,  Northern  Europe and Asia.  To date,  IBD has been
treated  post-hatch  via  manually  delivered  vaccines  or in  drinking  water.
Existing vaccines are associated,  however,  with certain limitations,  and some
cannot be used safely or effectively in ovo. The Company estimates the worldwide
market for IBD vaccines to be approximately $60 million annually.

In January 1995,  USDA approval was obtained for  post-hatch  administration  of
Bursaplex(TM),  the Company's  VNF(R)-based vaccine for IBD in broiler chickens.
USDA  approval  was  obtained in January  1997 for in ovo use of  Bursaplex(TM),
specifically for administration via Embrex's INOVOJECT(R) egg injection systems.
During 1997, the Company  conducted  clinical trials of Bursaplex(TM)  involving
more than 43.5 million birds, which Embrex believes  demonstrated clear economic
benefits of this IBD vaccine.

In August 1995,  the Company  entered into an agreement  with Cyanamid  Websters
("Websters"), a unit of Ft. Dodge Animal Health, which is a division of American
Home Products Corp., for the joint development of another IBD vaccine containing
VNF(R),  which will be  marketed by Websters  in Europe,  the Middle  East,  and
Africa under  Websters'  trade name  "Bursamune(TM)"  upon receipt of regulatory
approvals.  In June 1997,  the Company  announced  that Ft. Dodge Animal  Health
indicated  that  its  application  for  U.K.  in  ovo  regulatory   approval  of
Bursamune(TM) had been provisionally refused. Both the Company and Ft. Dodge had
anticipated  approval by the middle of 1997,  however,  Ft. Dodge indicated that
the U.K.  regulatory  authority  requested  that further  data be supplied.  The
Company  is working  with Ft.  Dodge and  Websters,  which are  responsible  for
obtaining the necessary  approvals for  Bursamune(TM) in both the U.K. and other
European Community markets, to respond to the U.K. regulatory authority requests
for data with respect to Bursamune(TM).  The Company anticipates that regulatory
approval in the U.K., as well as some other  European  Community  markets,  will
occur during summer of 1998.

Embrex intends to seek regulatory  approval in selected Latin American and Asian
markets  for in ovo and  post-hatch  use of  Bursaplex(TM).  Although  Embrex is
beginning  to  initiate  this  process,  there  is no  assurance  that  any such
regulatory approvals will be obtained.  Moreover,  the placement of INOVOJECT(R)
systems outside the U.S. and Canada is



                                       4
<PAGE>


dependent  on  regulatory  approval  and  market  acceptance  of  various in ovo
vaccines.  To date,  regulatory  approval for Bursaplex(TM) has been received in
Peru, Ecuador, Pakistan and, on a provisional basis, in South Korea.

PRODUCTS UNDER DEVELOPMENT

Embrex is developing  individually and in collaboration  with others  additional
products which address poultry health and performance needs when administered in
ovo. These additional  products are in various stages of development.  There can
be no  assurance  that Embrex will  successfully  develop or market any of these
products.  Marketing  products developed jointly with others may require royalty
or other payments by Embrex to its  co-developers.  Embrex has not initiated the
regulatory approval process for any of these potential products, and there is no
assurance regulatory approval will be obtained.

In Ovo Products for Control of Coccidiosis

In 1995, the Company began an initiative  aimed at development of a novel in ovo
biological control method for coccidiosis.  Coccidiosis is caused by a protozoan
parasite which attacks the gut of the chicken, causing significant problems with
the intake and  digestion  of feed and,  therefore,  the  physical  and economic
performance of the bird.  Currently,  virtually all broiler  chickens,  and most
poultry in general,  receive  anti-coccidiosis  compounds  called  coccidiostats
incorporated  into poultry feed. Over the years,  coccidia have developed levels
of resistance to these  coccidiostats  and thus  effectiveness has been somewhat
reduced.  A limited  number of live  vaccines  have also been  developed and are
administered orally soon after hatch.  However, due to difficulties in providing
a precise oral dose to each bird, growth depression can occur in broiler flocks.
Therefore,  such live  vaccines are used  primarily in parent  stock.  Using its
INOVOJECT(R)  technology and its knowledge of avian embryology,  the Company has
begun this initiative to develop a novel,  efficacious and cost-effective  means
of preventing  coccidiosis in broiler chickens,  aimed at overcoming many of the
problems associated with current practices. In 1997, the Company established the
feasibility of an in ovo  biological  control  method for  coccidiosis.  Further
development of this project  will involve  extensive  clinical  trials.  Embrex
intends to pursue this research  with  collaborative  partners.  There can be no
assurances that any of these development efforts will be successful.  Embrex has
not initiated the regulatory  approval process with respect to these development
efforts,  and does not  expect  for any  coccidiosis  product  developed  by the
Company to reach the market in the near future.

Other Products Under Development

During 1997, Embrex continued the evaluation process for several compounds which
the Company  believes may have the potential to yield  improvements in the areas
of feed  conversion,  muscle mass and leanness  within broiler  chickens.  These
compounds  need to be  administered  in the  first  several  days  of  embryonic
development  in order to have the desired  effect.  While the  Company  plans to
continue its research  efforts in this area in 1998,  there is no assurance that
these efforts will yield product opportunities.

Embrex also is researching technology alternatives to enhance or automate sexing
and  gender  sorting  practices  for  poultry.  Early  gender  sorting  improves
processing  plant  efficiencies  by enabling  gender-specific  feed  rations and
improved feed  conversion.  There is no assurance,  however,  that such research
will result in product opportunities.

Embrex routinely enters into collaborative agreements with various animal health
companies,  pharmaceutical  companies and research and academic  institutions to
evaluate the utility of certain of their  compounds or devices when delivered or
applied in ovo. Depending upon the outcome of these tests, Embrex may or may not
proceed with these collaborations for further development. There is no assurance
that these efforts will yield products or further collaborations.

PATENTS AND PROPRIETARY RIGHTS

Embrex controls (either through direct ownership or exclusive license) 21 issued
U.S. patents,  10 pending U.S. patent  applications,  and over 34 issued foreign
patents and 42 pending  foreign  patent  applications.  In addition,  Embrex has
executed   confidentiality   agreements   with  its  employees,   collaborators,
subcontractors and directors.

The  INOVOJECT(R)  system  utilizes a process of injecting  viral,  bacterial or
fungal  vaccines  into avian eggs that was  patented  in the U.S. by the USDA in
1984.  Embrex holds the exclusive  license to this patent through its expiration
in



                                       5
<PAGE>


2002.  Embrex has supplemented the USDA patent with five additional  issued U.S.
patents (and multiple foreign patents and patent applications) covering specific
design features of the  INOVOJECT(R)  system.  See Item 3, "Legal  Proceedings,"
below.

Embrex also owns or licenses method-of-use patents for the in ovo administration
of VNF(R) vaccines and other compounds to elicit various beneficial responses in
poultry.  Two U.S.  patents for methods of treating IBD virus  infections  using
VNF(R) vaccines,  including by in ovo  administration,  were issued to Embrex in
March 1995. A U.S. patent application claiming the use of VNF(R) vaccines in all
non-primate  animals was allowed in 1997.  These patents and  additional  patent
applications  encompass the use of the compounds regardless of the source of the
compound.

Embrex  additionally owns or licenses  composition-of-matter  patents for VNF(R)
vaccines   against  IBD  virus  disease.   A  U.S.   patent   application   with
composition-of-matter  claims to VNF(R) vaccines for combating viral diseases in
non-primate  animals was allowed  in1997.  These patent claims cover the vaccine
preparation, regardless of the manner in which the preparation is used.

In 1997, two additional U.S.  patent  applications  were filed covering  various
aspects of in ovo technology.

Embrex  continues its efforts to patent methods of delivering  compounds in ovo,
including early intervention methods and devices. In 1997, two U.S. patents with
claims to methods of  delivering  compounds to avian embryos in ovo were allowed
or issued.

Additionally,   Embrex  has  federally  registered  the  trademarks   EMBREX(R),
INOVOJECT(R),  and  VNF(R),  and has applied  for  federal  registration  of the
trademarks Bursaplex(TM) and Fortimune(TM).

COMPETITION

The primary  competition for the INOVOJECT(R)  system is the manual,  post-hatch
administration  of  biological  products.  As  most  of  Embrex's  products  and
potential   products  are  being  designed  to  be   administered   through  the
INOVOJECT(R) system, the INOVOJECT(R) system must continue to be accepted within
the  poultry  industry  and  operate  as  intended  under  long-term  commercial
conditions in order for these potential products to be marketed successfully.

The  Company  holds the  exclusive  license  to the U.S.  patent  for  injecting
vaccines into an avian  embryo.  Embrex has  supplemented  this patent with five
additional U.S.  patents  covering  specific design features of the INOVOJECT(R)
system.  In addition,  Embrex relies on numerous  foreign patents to protect its
intellectual properties and to afford a competitive advantage.  See "Patents and
Proprietary  Rights,"  above.  There  can  be  no  assurance,  however,  that  a
competitive  delivery method,  either within or outside the United States,  will
not be developed and gain commercial acceptance. Embrex continues to monitor for
the presence of any competitive in ovo  administration  systems  worldwide.  See
Item 3, "Legal Proceedings," below.

Competitive success for Embrex will be based primarily on commercial  acceptance
of its products,  achieving and retaining scientific expertise and technological
superiority,  identifying and pursuing  scientifically feasible and commercially
viable  opportunities,   obtaining  proprietary   protection  for  its  research
achievements,  obtaining adequate funding and timely regulatory  approvals,  and
attracting corporate sponsors or partners in developing, testing, producing, and
marketing  products,  none of which  can be  assured.  In  addition,  a  primary
competitive  factor  affecting  Embrex is its  ability to conduct  research  and
development.  Embrex's  ability to compete  also is  dependent on its ability to
attract and retain key  personnel.  Maintaining  financial and human  resources,
therefore, are important factors for success.

PRODUCTION, MARKETING AND DISTRIBUTION

Production

Embrex  currently  subcontracts  the  production  of  substantially  all  of its
mechanical  and  biological  products  and  expects to continue to do so for the
foreseeable future. The Company believes that alternative sources of manufacture
and supply generally exist.



                                       6
<PAGE>


INOVOJECT(R) System

Embrex's  in-house  engineering  staff designs the  INOVOJECT(R)  system,  which
incorporates  proprietary  mechanical,  pneumatic and electronic sub-systems and
concepts.  The Company uses a single  contract  manufacturer  to  fabricate  its
INOVOJECT(R) systems. While other machine fabricators exist and have constructed
limited numbers of INOVOJECT(R)  systems,  a change in fabricators could cause a
delay in manufacturing and a possible delay in the timing of future INOVOJECT(R)
installations and revenues from those installations.

VNF(R) (Viral Neutralizing Factor)

In 1993, Embrex signed multi-year  agreements with SPAFAS, Inc., a subsidiary of
Charles  River  Laboratories,  Inc.,  under which  SPAFAS will supply the active
ingredient  in VNF(R).  In  connection  with this  agreement,  Embrex  maintains
appropriate  inventory  levels and places  orders with SPAFAS to allow Embrex to
satisfy anticipated  customer demand for VNF(R). The regulatory approval granted
by the USDA for  Bursaplex(TM) in January 1997  specifically  covers the vaccine
produced with SPAFAS-manufactured VNF(R).

The Company has granted Select  Laboratories,  Inc.  ("Select"),  a wholly-owned
subsidiary  of Rhone  Merieux SA,  exclusive  rights to  manufacture  Infectious
Bursal  Disease   vaccines   containing   Embrex's  VNF(R)  product,   known  as
Bursaplex(TM),  for Embrex to market in North  America,  Latin America and Asia.
Embrex has also  granted  Websters  (a unit of  American  Home  Products  Corp.)
exclusive  rights to manufacture  IBD vaccines  containing the Company's  VNF(R)
product,  known as Bursamune(TM),  to be marketed in Europe, the Middle East and
Africa.  The  manufacture  of the IBD  vaccines  being  produced  by Select  and
Websters,  and the  Company's  VNF(R)  product,  generally  must be performed in
licensed  facilities or under approved  regulatory  methods.  Although there are
other  manufacturers who are capable of manufacturing IBD products and producing
products such as VNF(R),  a change of supplier for the Company  could  adversely
affect  Embrex's  future  operating  results due to the time it would take a new
supplier  to  obtain   regulatory   approval  of  its   production   process  or
manufacturing facilities.

Marketing and Distribution

Because of the geographical and industrial concentration of the poultry industry
in the U.S.,  Embrex markets its products and provides  ongoing service directly
to the  industry.  Embrex's  marketing  is focused  principally  on the  broiler
chicken  segment of the poultry  industry,  but the Company also has adapted its
products for use by and initiated  trials and entered into commercial  contracts
with a limited number of turkey producers.

In order to encourage proper use of the INOVOJECT(R) system technology within an
appropriate  production  environment,  Embrex  leases and licenses  INOVOJECT(R)
systems to hatcheries.  The agreements cover the use of the mechanical equipment
and ongoing field service,  maintenance  and technical  support.  The agreements
also  include  a  license  with  royalty  fees for use of  Embrex's  proprietary
injection process. Products which are delivered in ovo are sold separately.

The Company also is initiating  arrangements for  international  distribution of
IBD vaccines,  subject in each case to the  availability of required  regulatory
approvals.  In 1996, the Company  entered into  agreements with other parties to
distribute  Bursaplex(TM)  in Israel,  Chile,  Ecuador,  Peru and Pakistan.  The
agreement for Israel also entitles the distributor to manufacture a VNF(R)-based
IBD  vaccine.  Subject  to these  agreements,  the  Company  also  will  conduct
international marketing directly.

Other  significant  poultry markets exist in Asia and Latin America.  Embrex has
held a number of discussions  regarding  marketing and  distribution  in each of
these markets.  In 1997, the Company  entered into agreements with other parties
to distribute Bursaplex(TM) in South Korea, Malaysia, Taiwan, Japan and Vietnam,
subject to regulatory approvals. Embrex also hired management for selected Asian
and Latin American markets and installed INOVOJECT(R) systems on a commercial or
trial basis in certain Asian markets.

Embrex has  initiated  activities  necessary  for the  commercialization  of its
technology in Japan. In 1992, Embrex entered into a distribution  agreement with
Ishii  Company,  Ltd.  ("Ishii"),  a leading  chick  producer  and the  dominant
supplier  of  hatchery  equipment  in  Japan.  Upon  veterinary  medical  device
regulatory  approval by the  Japanese  Ministry of  Agriculture,  Fisheries  and
Forestry,  Ishii intends to distribute the  INOVOJECT(R) egg injection system to
poultry producers throughout Japan.



                                       7
<PAGE>


The Company's  revenues  attributable to international  operations in 1997, 1996
and  1995  were  9%,  10%  and  6%  of  the  Company's   consolidated  revenues,
respectively.  The company's  identifiable  assets attributable to international
operations  in  1997,  1996  and  1995  were  16%,  13% and 5% of the  Company's
consolidated assets, respectively.

RESEARCH AND DEVELOPMENT

In  February  1998,  Embrex  opened a 12,800  square foot  research  and testing
facility  near the  Company's  headquarters.  This new  facility  is expected to
increase  the  Company's  clinical  trial  capabilities  and reduce  reliance on
contract  research.  Research and development  expense was $3.4 million in 1995,
$3.7  million in 1996 and $3.8  million in 1997.  The  increase in research  and
development  expense  from 1995 to 1997  largely  reflects  increases in outside
contract research, supplies consumption, and INOVOJECT(R) design and development
activity.  Research and development is principally  Company sponsored and funded
primarily from internal sources.

GOVERNMENTAL REGULATION

Regulation  by  governmental  authorities  in the U.S. and other  countries is a
significant  factor in the production and marketing of Embrex's  products and in
its  on-going  research  and  development  activities.  Although  the use of the
INOVOJECT(R)  system is not subject to regulatory  approval in the U.S.,  animal
health  products being  developed by Embrex must receive  approval for marketing
from  either the USDA or the Food and Drug  Administration  (the "FDA") and from
similar   agencies  in  foreign   countries  where  the  Company  has  begun  or
contemplates  doing business.  These countries may also require  approval of the
INOVOJECT(R)  system.  Regulatory  agencies  require that  products be tested in
animals and demonstrate  appropriate  levels of safety and efficacy.  Generally,
with respect to animal health products,  the USDA has regulatory  authority over
products which are biological in origin or which stimulate or affect an animal's
immune system,  and the FDA has authority over all other products.  The time and
cost of USDA  approvals are  generally  less than those for FDA  approvals.  FDA
approval  generally  requires more extensive animal and toxicology  testing than
USDA approvals and may take five or more years to obtain, whereas USDA approvals
generally  require  one to three  years to obtain.  Embrex's  VNF(R)  technology
received USDA approval in January 1995 for IBD applications  post hatch, and for
in ovo use in January 1997. Of Embrex's  products  currently under  development,
only the growth enhancing compounds and certain gene therapy products (depending
on the nature of the genetic  material  and the  response  induced) are known to
require  FDA  approval.   Embrex  believes  all  of  its  other  products  under
development will be subject only to USDA approval.  Embrex's  existing  products
have  received all  necessary  governmental  approvals in the U.S. The Company's
products also are subject to regulatory approval in other countries.

Management believes that compliance with environmental regulations currently has
no material adverse effect on the Company's  capital  expenditures,  earnings or
competitive position.

EMPLOYEES

At December 31, 1997,  Embrex  employed 121 persons,  115 of whom were full-time
employees,  an  increase  of 14  persons  from the 101  full-time  employees  at
December 31, 1996.

SIGNIFICANT CUSTOMERS

Tyson Foods, Inc., including Hudson Foods which was acquired by Tyson in January
1998 ("Tyson"),  accounted for approximately  28% of Embrex's  consolidated 1997
revenues.  Based on millions of pounds of ready-to-cook poultry meat produced in
1997,  Tyson accounted for  approximately  26% of the broilers grown in the U.S.
During 1997,  Tyson extended its contract with Embrex through 2004. There are no
customers  besides Tyson that represent 10 percent or greater of total revenues.
However, Perdue Farms and ConAgra Poultry accounted for approximately 8% and 7%,
respectively, of consolidated 1997 revenues.



                                       8
<PAGE>


ITEM 2. PROPERTIES

Embrex  leases  its  corporate   headquarters   and  research  and   development
facilities,  which  occupy  approximately  23,000  square  feet and are  located
adjacent to Research  Triangle Park, North Carolina.  Two-thirds of the space is
devoted to research and  development.  The lease is for a 15-year term  expiring
March 31,  2002.  Embrex paid an annual rent of  approximately  $215,000  during
1997.  Annual rent increases  thereafter amount to approximately 3%. In addition
to research and development activities conducted at its corporate  headquarters,
Embrex opened a new 12,800  square foot  research and testing  facility near its
headquarters in February 1998. The lease is for a 10-year term expiring November
14,  2007,  with a 5-year  renewal  option.  The  annual  rent is  approximately
$135,000,  with annual  increases of approximately 3% through the first 10 years
and approximately 4% during the 5-year renewal term.

Embrex leases  approximately 3,000 square feet of warehouse space in Springdale,
Arkansas,  on a year-to-year basis, which is used to support the Embrex customer
service function in the region.  The Company also leases offices of 1,250 square
feet and  warehouse  space of 850 square feet in Great Dunmow,  Essex,  England.
Embrex is in the  process  of  negotiating  a new 2,500  square  foot  warehouse
facility  near its  offices in England  that will  replace  the 850 square  foot
facility.  The warehouse  will provide  additional  operating  space and a close
proximity to the headquarters  office.  The incremental rent for the replacement
warehouse is not expected to exceed $13,000 annually.  Embrex also has access to
facilities at certain universities.  The use of these facilities is important to
Embrex's  ongoing  research and development  efforts.  Embrex has had agreements
with North Carolina State  University  ("NCSU")  providing  access to facilities
used for  incubating  eggs and growing  live birds and for  research and testing
purposes.  Reliance on the NCSU facilities is expected to decline as a result of
Embrex's  new research  and testing  facility.  Embrex  believes  that  suitable
alternative facilities exist if the above agreements are not renewed.

ITEM 3. LEGAL PROCEEDINGS

In September 1996, Embrex filed a patent  infringement suit in the United States
District  Court for the  Eastern  District  of North  Carolina  against  Service
Engineering  Corporation,  a Maryland corporation,  and Edward G. Bounds, Jr., a
Maryland  resident  and  officer of Service  Engineering  Corporation.  The suit
alleged that each of the defendants'  development of an in ovo injection device,
designed  to compete  with  Embrex's  patented  INOVOJECT(R)  injection  method,
infringes  at least  one  claim of the U.S.  patent  No.  4,458,630  exclusively
licensed to Embrex for the in ovo  injection  of vaccines  into an avian  embryo
(the "Sharma Patent").  Further, Embrex claims that the defendants have violated
the terms of a Consent  Judgment  and  Settlement  Agreement  entered  into with
Embrex in November 1995 in which prior  litigation  was  concluded  with Service
Engineering and Bounds agreeing not to engage in future activities violating the
Sharma Patent.  Embrex sought injunctive  relief to prevent  infringement of the
Sharma Patent as well as monetary damages. In November 1996, Service Engineering
Corporation and Edward G. Bounds responded to Embrex's patent  infringement suit
by  asserting   various   affirmative   defenses  and  denying  the  substantive
allegations  in  Embrex's  complaint.  This  suit is  still  pending  and  final
disposition is expected in 1998.

In November 1996,  Embrex filed a patent  infringement suit in the United States
District Court for the Eastern  District of North Carolina  against IGI, Inc., a
Delaware corporation.  The suited alleged that IGI, Inc., through its activities
with Service  Engineering  Corporation and Edward G. Bounds,  Jr., an officer of
Service  Engineering  Corporation,  is engaging in  activities  that  constitute
infringement of the Sharma Patent.  Embrex sought  injunctive  relief to prevent
infringement of the Sharma Patent as well as monetary damages.  In January 1997,
IGI, Inc.  responded to Embrex's patent  infringement  suit by asserting various
affirmative  defenses  and  denying  the  substantive  allegations  in  Embrex's
complaint.  This suit was concluded by agreement between Embrex and IGI, Inc. in
January 1998.

In March 1997, Service  Engineering  Corporation,  a Maryland  corporation,  and
Edward G. Bounds, Jr., a Maryland resident and an officer of Service Engineering
Corporation,  filed suit against the United States  Department of Agriculture in
the United  States  District  Court for the District of Maryland with respect to
its grant to Embrex of an exclusive license for the Sharma Patent. The complaint
alleges that the USDA did not  adequately  comply with  statutory and regulatory
requirements in making the grant to Embrex of an exclusive license to the Sharma
Patent,  the revision of the  exclusive  license in 1991 and the revision of the
exclusive license in 1994, which extended the period of exclusivity,  originally
set to  terminate  on December 31,  1996,  through the patent  expiration  date.
Plaintiffs  allege that in December 1996 (after Embrex had  instituted the above
referenced  action  for  patent  infringement  and  breach  of  contract),   the
Plaintiffs  requested the USDA to grant them a license of the Sharma Patent. The
Plaintiffs  allege that the USDA refused to do so because the USDA said that the
license  was not  available  and that the  Plaintiffs  had no basis for  relief.
Plaintiffs also



                                       9
<PAGE>


allege that the USDA wrongfully  consented to Embrex's bringing suit against the
Plaintiffs.  Plaintiffs are seeking to have the court set aside the extension of
the exclusive license,  the USDA's grant of permission for Embrex to sue Service
Engineering  Corporation,  Edwards  G.  Bounds,  Jr.  and IGI,  Inc.  for patent
infringement,  the USDA's refusal to grant to Service Engineering  Corporation a
non-exclusive  license  to the  Sharma  Patent  and the  USDA's  refusal  to act
favorably  upon  Service  Engineering  Corporation's  appeal from the refusal to
grant it a non-exclusive license. In addition, Plaintiffs seek to have the court
issue an order requiring the USDA, prior to granting any exclusive license under
the Sharma Patent,  including by extending the term of a pre-existing  exclusive
license,  to  observe  the  procedures  set  forth  under  laws and  regulations
governing the grant of licenses to patents owned by the USDA,  and to remand the
matter to the USDA to take action in accordance with the order.  Plaintiffs also
seek  attorneys'  fees and costs from the USDA.  This suit was stayed in January
1998 for 60 days  pending  resolution  of the suit  between  Embrex and  Service
Engineering  Corporation  and Edward G. Bounds,  Jr. See "Risk Factors" filed as
Exhibit 99 to this report.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

No  matters  were  submitted  to a vote of  security  holders  during the fourth
quarter of the fiscal year ended December 31, 1997.



                                       10
<PAGE>


                                     PART II

ITEM 5. MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED STOCKHOLDER MATTERS

The Company's Common Stock trades on the Nasdaq National Market System under the
symbol EMBX. The quarterly  trading ranges of the Company's Common Stock for the
last two fiscal years were as shown in the table below:

                                                     Common Stock
                                                     Price Per Share
                                                  ----------------------
           Quarter Ended                          High               Low
           -------------                          ----               ---

           March 31, 1996......................   8 1/4              5 1/2
           June 30, 1996.......................   7 7/8              6
           September 30, 1996..................   7 3/8              6
           December 31, 1996...................   7 3/4              6
           March 31, 1997......................   7 13/16            6 3/8
           June 30, 1997.......................   7 3/8              6 3/16
           September 30, 1997..................   7 3/8              5 15/16
           December 31, 1997...................   7                  5

At February 27, 1998 (the most recent  practicable date), there were 504 holders
of record of the Common  Stock.  The Company has paid no  dividends on any stock
since  inception  and has no plans to pay  dividends  on its Common Stock in the
foreseeable future.

ITEM 6. SELECTED FINANCIAL DATA

Summary of Operations by Quarters (Unaudited)

<TABLE>
<CAPTION>
(Dollars In Thousands,
Except Per Share Amounts)                                1997                                              1996
- -----------------------------        -----------------------------------------------------------------------------------------------
                                     1st Qtr     2nd Qtr      3rd Qtr     4th Qtr      1st Qtr     2nd Qtr      3rd Qtr     4th Qtr
                                     -------     -------      -------     -------      -------     -------      -------     -------
<S>                                  <C>          <C>         <C>          <C>         <C>          <C>         <C>         <C>
Revenues.....................        $5,925       $5,922      $6,531       $6,412      $4,595       $5,068      $5,641      $ 5,328
Operating Expenses...........         2,577       $2,403       2,585        2,230       1,628        1,848       2,155        2,180
Net income (loss)............           262          417         540          542          58          193         203         (113)
Net income (loss) per share
   of Common Stock
       Basic.................        $ 0.03       $ 0.05      $ 0.06       $ 0.07      $ 0.01       $ 0.03      $ 0.03      $ (0.01)
       Diluted...............        $ 0.03       $ 0.05      $ 0.06       $ 0.07      $ 0.01       $ 0.03      $ 0.03      $ (0.01)

 Number of Shares Used
    in Per Share Calculation
       (thousands)
       Basic................           8,058       8,203        8,236       8,238       6,820        7,017       7,213        7,821
       Diluted...............          8,278       8,380        8,369       8,331       7,158        7,347       7,452        7,821
</TABLE>


                                       11
<PAGE>


5-Year Summary of Selected Financial Data
(Dollars In Thousands, Except Per Share Amounts)

<TABLE>
<CAPTION>
                                                             1997            1996            1995            1994             1993
                                                             ----            ----            ----            ----             ----
                                                                                          (Restated)
<S>                                                        <C>             <C>             <C>             <C>             <C>     
Statements of Operations Data
Revenues ...........................................       $ 24,789        $ 20,632        $ 13,719        $  6,897        $  2,159
Research and development expenses ..................          3,793           3,673           3,416           4,271           3,763
Other operating expenses ...........................          6,002           4,138           3,836           3,561           4,248
Net income (loss) ..................................          1,760             341          (4,512)         (6,710)         (7,307)
Net income (loss) per share of Common
Stock (thousands)
       Basic .......................................       $   0.21        $   0.05        $  (0.73)       $  (1.19)       $  (1.61)
       Diluted .....................................       $   0.21        $   0.06        $  (0.73)       $  (1.19)       $  (1.61)
Number of Shares Used in Per Share
Calculation (thousands)
       Basic .......................................          8,184           7,218           6,187           5,645           4,552
       Diluted .....................................          8,339           7,520           6,187           5,645           4,552

Balance Sheet Data
Working capital ....................................       $  7,581        $  7,552        $  5,934        $  1,608        $  9,370
Total assets .......................................         25,161          25,554          21,789          13,379          14,997
Long-term liabilities ..............................          3,278           5,814          10,966           3,093           1,377
Accumulated deficit ................................        (38,933)        (40,693)        (41,034)        (36,522)        (29,812)
Shareholders' equity ...............................         15,741          13,309           5,909           5,323          11,996
</TABLE>

ITEM 7. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS

RESULTS OF OPERATIONS

The following  discussion and analysis  should be read in  conjunction  with the
Company's  financial  statements and related notes  appearing  elsewhere in this
report.

Consolidated  net income for 1997 was $1.8 million  compared to $341,000 in 1996
and a net loss of $4.5 million,  on a restated basis, in 1995.  Diluted earnings
per share increased from a net loss of $0.73 in 1995, on a restated basis, and a
profit  of $0.05 in 1996,  to net  income of $0.21 in 1997.  For the year  ended
1997,  shares  outstanding on a diluted basis were 8.3 million,  up from 7.5 and
6.2 million at year-end 1996 and 1995, respectively.

Revenues

Consolidated revenues in 1997 totaled $24.8 million, representing an increase of
20% over 1996  revenues of $20.6  million,  which were 50% over 1995 revenues of
$13.7 million.  INOVOJECT(R)  revenues totaled $23.6 million in 1997 compared to
$19.3 million in 1996 and $12.8 million in 1995,  representing  increases of 22%
from 1996 to 1997,  and 50% from  1995 to 1996,  with the 1997  increase  coming
principally from increased  placement and throughput of INOVOJECT(R)  systems in
North America and Europe.

The 1997  revenues  include  INOVOJECT(R)  lease fees  derived  from  multi-year
contracts  and paid trials in the U.S.  and foreign  countries,  and the sale of
INOVOJECT(R) systems to distributors.  At December 31, 1997, Embrex had over 300
INOVOJECT(R)  systems installed and operating under lease agreements  worldwide,
up from over 250 systems at December  31,  1996,  and 235 at December  31, 1995.
Additionally,  Embrex estimates that as of December 31, 1997, it was vaccinating
in excess of 80% of the estimated 8.0 billion broiler birds grown in the U.S. in
1997, as well as



                                       12
<PAGE>


approximately  80% in 1996, and 66% in 1995. Given its market  penetration,  the
Company  expects  only  moderate  INOVOJECT(R)  systems  revenue  growth in this
market.

Management  anticipates  moderate  revenue  and  earnings  growth  in 1998  from
existing   INOVOJECT(R)   operations  in  the  United  States  and  Canada,  new
INOVOJECT(R)  system  leases  in other  countries,  and  sales of  Bursaplex(TM)
product to poultry  producers.  However,  the rate at which the marketplace will
accept the  INOVOJECT(R)  technology  outside the United States and Canada,  the
timing of regulatory  approvals of  third-party  vaccines for in ovo use outside
the  United  States  and  Canada,  start-up  costs  in  new  markets,   possible
variability  in U.S.  hatchery  bird  production  as a  result  of  grain  price
fluctuations,  and  possible  variability  in the  demand for U.S.  poultry  and
poultry  products  outside the U.S., will impact the pace of revenue growth,  if
any, and the sustaining of  profitability  from the installation and operational
throughputs  of  INOVOJECT(R)  systems.  In any event,  any revenue and earnings
growth  in 1998 is not  anticipated  to begin  prior  to the  third  and  fourth
quarters.

Sales of Bursaplex(TM),  the Company's  proprietary vaccine for the treatment of
avian  Infectious  Bursal Disease,  was the principal  source of $1.1 million of
product  revenues  in 1997.  The  previously  discussed  delay  associated  with
obtaining U.K.  regulatory  approval for the sale of  Bursamune(TM)  in the U.K.
reduced the sale of the Company's  proprietary  VNF(R)  product,  which is a key
component of  Bursamune(TM),  to Ft. Dodge Animal Health, a division of American
Home Products  Corp.  See "Business -- Existing  Products,"  above.  This offset
initial  sales of  Bursaplex(TM)  during  1997 and  consequently  resulted  in a
$155,000 decrease in product revenue from 1996. Sales of VNF(R) for inclusion in
IBD vaccines  were the principal  source of previous  years'  product  revenues,
which generated $1.2 million and $817,000 in 1996 and 1995, respectively.

Cost of Product Sales and INOVOJECT(R) Revenues

Cost of revenues as a percentage of revenues decreased from 53% and 64% of total
revenues in 1996 and 1995,  respectively,  to 49% of total revenues in 1997. The
improvement in 1997 is primarily  attributable  to  INOVOJECT(R)  system-related
cost reductions.

Operating Expenses

Operating  expenses  totaled  $9.8  million in 1997  compared to $7.8 million in
1996, and $7.3 million in 1995.

General and  administrative  ("G&A")  expenses were $5.5 million in 1997, up 49%
from $3.7 million in 1996,  and up 11% from $3.3  million in 1995.  The 1997 G&A
increase  was  primarily  attributable  to  development  costs in Asia and Latin
America as well as legal  expenses  incurred in connection  with various  patent
infringement  lawsuits  filed by the Company.  The 1996  increase  over 1995 was
largely due to increased legal expenses  associated with the implementation of a
shareholder  rights plan in March 1996 and amendments to the Company's  Articles
of Incorporation approved at the annual meeting of shareholders in May 1996.

Sales and marketing  expenses  totaled $522,000 in 1997 compared to $455,000 and
$525,000  in 1996 and 1995,  respectively.  Fluctuations  during  these  periods
resulted  from various  levels of activity in the  Company's  sales and customer
service  functions to support market expansion and field support of INOVOJECT(R)
systems, as well as stepped-up  international  activity,  principally in Europe.
Certain 1997, 1996, and 1995 operating  expenses were  reclassified to cost of
revenues to conform to the presentation  format adopted in the fourth quarter of
1996 and during 1997. These  reclassifications  had no effect on previously
reported net income or loss or shareholders' equity in 1995, 1996, or 1997.

Research and development  ("R&D") expenses were $3.8 million in 1997 compared to
$3.7 million in 1996 and $3.4 million in 1995.  The increase in R&D expense from
1995 to 1997 largely reflects an increase in outside contract research, supplies
consumption,  and  INOVOJECT(R)  design and  development  activity.  The Company
continues  to  manage  its  research  and  development  effort to  leverage  its
know-how, patent position, market presence and expenditures.


                                       13
<PAGE>


Other Income and Expense

Interest income totaled  $488,000,  $355,000,  and $389,000 in years 1997, 1996,
and 1995, respectively.  The 1997 increase relative to 1996 resulted principally
from higher cash  balances,  while the  decrease in 1996  relative to 1995 was a
function of lower interest rates.

Interest  expense totaled $1.1 million in 1997 compared to $1.6 million in 1996,
and $2.7  million,  on a restated  basis,  in 1995.  In 1997,  the  decrease  in
interest  expense  reflected  the  repayment  of  approximately  $3.3 million of
external financing, primarily in the form of equipment leases. In 1996 and 1995,
the amount of expense was principally  attributable to the Company's  funding of
its growing installed base of INOVOJECT(R) systems with the use of capital lease
financing and, in 1995, the issuance of  convertible  debentures.  Additionally,
interest  expense  for 1995 has been  restated  to  reflect  a  one-time  charge
associated with recognizing  $1,019,000 of interest expense  attributable to the
difference  between  the  market  price of the  Company's  Common  Stock and the
conversion  price of the  debentures  issued in 1995. See "Liquidity and Capital
Resources" and Note 12 to the Company's financial statements. Management expects
to continue to rely on the use of internally generated funds to finance the cost
of additional INOVOJECT(R) systems in 1998, as was the case in 1997.

Effect of Inflation

Management  expects cost of product  sales and  INOVOJECT(R)  systems  revenues,
operating  expenses and capital  equipment costs to change in line with periodic
inflationary  changes in price levels.  While Management generally believes that
the  Company  will be able to  offset  the  effect  of price  level  changes  by
adjusting  selling/lease  prices  and  effecting  operating  efficiencies,   any
material  unfavorable  changes in price  levels  could  have a material  adverse
affect on its results of operations.

Year 2000 Issue

Embrex's general ledger and primary financial accounting software is a DOS-based
application  that operates on a client- server network.  This  application  uses
only two digits to  identify a year in the date field.  The  Company  intends to
replace  this  application   during  1998  with  a   Windows(TM)-based   system.
Irrespective of the Year 2000 issue, the Company needs to upgrade its accounting
system to meet the  demands of its  business.  The  Company is in the process of
developing the implementation  plan for this upgrade.  The Company believes that
the additional  costs  associated with the Year 2000 aspects of the upgrade will
be immaterial.

LIQUIDITY AND CAPITAL RESOURCES

At December 31, 1997,  the Company's  cash and  short-term  investment  balances
totaled $8.6  million  compared to $9.9 million and $7.3 million at December 31,
1996 and 1995,  respectively.  The decrease reflected the ability of the Company
to fund capital  expenditures  with  internal  cash  instead of equipment  lease
financing.  Working capital remained  unchanged at $7.6 million in both 1997 and
1996, as a decrease in cash was offset by a reduction in the short-term portions
of both capital lease obligations and long-term debt.

During 1997,  operating activities generated $6.1 million in cash, primarily due
to  non-cash   depreciation,   and  net  income.  Within  investing  activities,
INOVOJECT(R)  systems,  the  Company's  new research and testing  facility,  and
equipment  purchases  required  $4.9  million,  while  the  sale  of  short-term
investments,  provided an offsetting $0.9 million. In addition, $3.1 million was
used to repay long-term debt and capital lease obligations.

During 1997,  $425,000 of outstanding  debentures along with $139,000 of accrued
interest were  converted  into 98,267 shares of Common Stock net of  unamortized
debt issuance costs totaling  $1,000.  In addition,  419 shares of Embrex Common
Stock were issued pursuant to the non-cash  exercise of warrants  related to the
initial  sale of the  debentures  in May  1995.  As of  December  1,  1997,  all
debentures had been converted into Common Stock.

As of December 31, 1997,  the Company had  outstanding  purchase  commitments of
approximately   $2.5  million   related  to  the  production  of  the  Company's
Bursaplex(TM)   product,   and  materials  and  supplies  for  construction  and
maintenance of INOVOJECT(R) egg injection systems.  This commitment included the
obligation related to a January 1996 agreement



                                       14
<PAGE>


reached with Select Laboratories, requiring the Company to purchase all existing
inventories of raw materials,  Bursaplex(TM),  and related materials from Select
within 30 months  following  the January  1997 receipt of in ovo approval of the
Bursaplex(TM)  product  being  manufactured  for Embrex.  In January  1998,  the
Company fulfilled its obligation to Select under the January 1996 agreement.

The Company  maintains a $2.0 million  secured line of credit with a bank in the
United  Kingdom,  which may be used to finance the  construction  of  additional
INOVOJECT(R)  systems  for  Europe,  the Middle  East and  Africa.  The  Company
utilized $0.3 million of this line in 1997,  with the balance of $1.7  available
at year end. A remaining  commitment of $2.0 million for  utilization  by Embrex
under a collaterized equipment financing arrangement expired in June 1997.

Based on its current operations, management believes that its available cash and
short-term  investments,  together  with  cash  flow  from  operations,  will be
sufficient to meet its foreseeable cash requirements.

FORWARD-LOOKING STATEMENTS

Information  set  forth in this  Annual  Report on Form  10-K  contains  various
"forward looking statements" within the meaning of Section 27A of the Securities
Act of 1933 and  Section  21E of the  Securities  Exchange  Act of  1934,  which
statements  represent  the  Company's  judgment  concerning  the  future and are
subject  to risks  and  uncertainties  that  could  cause the  Company's  actual
operating  results and  financial  position to differ  materially.  Such forward
looking  statements can be identified by the use of forward looking  terminology
such  as  "may,"  "will,"  "expect,"  "anticipate,"  "estimate,"  "believe,"  or
"continue," or the negative  thereof or other  variations  thereof or comparable
terminology.

The  Company  cautions  that any such  forward  looking  statements  are further
qualified by important  factors that could cause the Company's  actual operating
results to differ  materially  from  those in the  forward  looking  statements,
including without limitation the Company's ability to penetrate new markets, the
Company's  dependence  on certain  customers;  the ability of the  Company,  its
manufacturing and marketing  partners and others to obtain  regulatory  approval
for products,  which is dependent on a number of factors,  including the results
of trials, the discretion of regulatory officials,  and any potential changes in
regulations; the Company's ability to generate future cash flow from operations;
continued demand for the INOVOJECT(R)  system;  the successful outcome of patent
litigation;  the Risk Factors described in Exhibit 99 to this report;  and other
risks  detailed  from  time to time in the  Company's  Securities  and  Exchange
Commission filings, including the Company's Forms 10-Q, 10-K, and 8-K.


                                       15
<PAGE>


ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

                         Report of Independent Auditors

The Board of Directors and Shareholders
Embrex Inc.

We have audited the accompanying consolidated balance sheets of Embrex, Inc. and
subsidiaries  as of  December  31, 1997 and 1996,  and the related  consolidated
statements of  operations,  shareholders'  equity and cash flows for each of the
three  years  in  the period ended December 31, 1997. These financial statements
are the responsibility of the Company's management.   Our responsibility  is  to
express  an  opinion  on  these  financial statements based on our audits.

We  conducted  our  audits  in  accordance  with  generally   accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management, as well as evaluating the overall financial statement presentations.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the consolidated  financial statements referred to above present
fairly, in  all  material  respects,  the financial position of Embrex, Inc. and
subsidiaries  at  December 31,  1997  and  1996, and the consolidated results of
their  operations and their cash flows for each of the three years in the period
ended  December 31, 1997,  in  conformity  with  generally  accepted  accounting
principles.

                                                /s/ Ernst & Young LLP


Raleigh, North Carolina
February 20, 1998


                                       16
<PAGE>


Consolidated Balance Sheets

(Dollars in thousands)

<TABLE>
<CAPTION>
                                                                                                                 December 31
                                                                                                        ---------------------------
ASSETS                                                                                                    1997               1996
                                                                                                        --------           --------
<S>                                                                                                     <C>                <C>     
Current Assets
     Cash and cash equivalents ...............................................................          $  8,580           $  9,036
     Restricted Cash (Note 2) ................................................................               275                  0
     Short-term investments (Note 3) .........................................................                 0                876
     Inventories:
         Materials and supplies ..............................................................               898              1,061
         Product .............................................................................               603                573
     Accounts receivable - trade .............................................................             2,772              2,313
     Other current assets ....................................................................               595                124
                                                                                                        --------           --------
         Total Current Assets ................................................................            13,723             13,983

INOVOJECT(R)Systems Under Construction .......................................................               690                530

INOVOJECT(R)Systems ..........................................................................            21,024             18,193
     Less accumulated depreciation ...........................................................           (12,149)            (8,499)
                                                                                                        --------           --------
                                                                                                           8,875              9,694

Equipment, Furniture and Fixtures ............................................................             3,601              2,607
Less accumulated depreciation ................................................................            (2,041)            (1,695)
                                                                                                        --------           --------
                                                                                                           1,560                912
Other Assets:
     Patents and exclusive licenses of patentable technology
         (net of accumulated amortization of $80 in 1997 and $58 in 1996) ....................               309                125
     Other noncurrent assets .................................................................                 4                310
                                                                                                        --------           --------
Total Assets .................................................................................          $ 25,161           $ 25,554
                                                                                                        ========           ========

LIABILITIES AND SHAREHOLDERS' EQUITY
Current Liabilities
     Accounts payable ........................................................................          $  1,312           $  1,355
     Accrued expenses ........................................................................             2,147              1,087
     Current portion of capital lease obligations ............................................             2,391              3,080
     Current portion of long-term debt (Note 5) ..............................................               292                909
                                                                                                        --------           --------
              Total Current Liabilities ......................................................             6,142              6,431

Capital Lease Obligations, less current portion (Note 4) .....................................             3,269              5,806
Long-Term Debt, less current portion (Note 5) ................................................                 9                  8
Shareholders' Equity (Notes 6, 7 and 8)
     Common Stock, $.01 par value per share
         Authorized - 30,000,000 shares
         Issued and outstanding- 8,239,946 and 8,043,490 shares at
              December 31, 1997 and 1996, respectively .......................................                82                 80
     Additional paid-in capital ..............................................................            54,788             53,742
     Currency translation adjustments ........................................................              (196)               180
     Accumulated deficit .....................................................................           (38,933)           (40,693)
                                                                                                        --------           --------
         Total Shareholders' Equity ..........................................................            15,741             13,309
                                                                                                        --------           --------
Total Liabilities and Shareholders' Equity ...................................................          $ 25,161           $ 25,554
                                                                                                        ========           ========
</TABLE>


                                       17
<PAGE>


Consolidated Statements of Operations

(In thousands, except per share amounts)

<TABLE>
<CAPTION>
                                                                                              Year ended December 31,
                                                                                 --------------------------------------------------
                                                                                   1997                 1996                 1995
                                                                                 --------             --------             --------
                                                                                                     (Restated)
<S>                                                                              <C>                  <C>                  <C>     
Revenues
    INOVOJECT(R)revenue .............................................            $ 23,614             $ 19,263             $ 12,806
    Product revenue .................................................               1,062                1,217                  817
    Other revenue ...................................................                 113                  152                   96
                                                                                 --------             --------             --------
        Total Revenues ..............................................              24,789               20,632               13,719
Cost of Product Sales and INOVOJECT(R)Revenues ......................              12,244               11,032                8,714
                                                                                 --------             --------             --------
                                                                                   12,545                9,600                5,005

Operating Expenses
    General and administrative ......................................               5,480                3,683                3,311
    Sales and marketing .............................................                 522                  455                  525
    Research and development ........................................               3,793                3,673                3,416
                                                                                 --------             --------             --------
        Total Operating Expenses ....................................               9,795                7,811                7,252
                                                                                 --------             --------             --------

Operating Income (Loss) .............................................               2,750                1,789               (2,247)
Other Income (Expense)
    Interest income .................................................                 488                  355                  389
    Interest expense ................................................              (1,070)              (1,608)              (2,654
    Other ...........................................................                  14                    0                    0
                                                                                 --------             --------             --------
        Total Other Expense .........................................                (568)              (1,253)              (2,265)
                                                                                 --------             --------             --------
        Income (Loss) Before Taxes ..................................               2,182                  536               (4,512)
Income Taxes (Note 10) ..............................................                 422                  195                    0
                                                                                 --------             --------             --------
Net Income (Loss) ...................................................            $  1,760             $    341             $ (4,512)
                                                                                 ========             ========             ========
Net Income (loss) per share of Common Stock
        Basic .......................................................            $   0.21             $   0.05             $  (0.73)
        Diluted .....................................................            $   0.21             $   0.06             $  (0.73)

Number of Shares Used in Per Share Calculation
        Basic .......................................................               8,184                7,218                6,187
        Diluted .....................................................               8,339                7,520                6,187
</TABLE>


See accompanying notes.


                                       18
<PAGE>


Consolidated Statements of Cash Flows

<TABLE>
<CAPTION>
(Dollars in thousands)                                                                               Year ended December 31,
                                                                                           ----------------------------------------
                                                                                             1997            1996            1995
                                                                                           --------        --------        --------
                                                                                                                          (Restated)
<S>                                                                                        <C>             <C>             <C>      
Operating Activities
     Net income (loss) .............................................................       $  1,760        $    341        $ (4,512)
     Adjustments to reconcile net loss to net cash provided by (used in)
        operating activities:
         Depreciation and amortization .............................................          4,043           4,021           3,443
         Changes in operating assets and liabilities:
              Accounts receivable, inventories and other current assets ............           (797)           (515)         (1,610)
              Accounts payable and accrued expenses ................................          1,083             119             (64)
                                                                                           --------        --------        --------
Net Cash Provided By (Used In) Operating Activities ................................          6,089           3,966          (2,743)
Investing Activities
     Purchases of short-term investments ...........................................              0               0            (147)
     Sales of short-term investments ...............................................            876           1,096               0
     Collateralization of Lease (Note 2) ...........................................           (275)              0               0
     Purchases of INOVOJECT(R)systems, equipment, furniture and fixtures ...........         (3,962)         (4,888)         (7,330)
     Reductions to patents and other noncurrent assets .............................            280              93             111
                                                                                           --------        --------        --------
Net Cash Provided By (Used In) Investing Activities ................................         (3,081)         (3,699)         (7,366)
Financing Activities
     Issuance of Common Stock ......................................................            257           3,438             927
     Issuance of long-term debt ....................................................           (119)            476           6,403
     Proceeds from capital lease obligations .......................................            102           2,139           7,101
     Payments on capital lease obligations .........................................         (3,328)         (2,818)         (1,771)
                                                                                           --------        --------        --------
Net Cash Provided By (Used In) Financing Activities ................................         (3,088)          3,235          12,660
                                                                                           --------        --------        --------
Increase (Decrease) In Cash And Cash Equivalents ...................................            (80)          3,502           2,551
Currency Translation Adjustments ...................................................           (376)            180            --
Cash and cash equivalents at beginning of period ...................................          9,036           5,354           2,803
                                                                                           --------        --------        --------
Cash and Cash Equivalents at End of Period .........................................       $  8,580        $  9,036        $  5,354
                                                                                           ========        ========        ========
</TABLE>

Supplemental Disclosure of Cash Flow Information

Total  interest paid was  $1,070,000,  $1,593,000  and  $1,635,000 for the years
ended December 31, 1997, 1996, and 1995, respectively.

Total  income  taxes  paid was  $70,000,  $170,000  and $0 for the  years  ended
December 31, 1997, 1996 and 1995, respectively.

Supplemental Schedule of Noncash Financing Activity:

In May 1995,  American Cyanamid Company,  a subsidiary of American Home Products
Corp., converted the promissory note issued by Embrex, Inc. to American Cyanamid
in 1991.  The $1.2 million note,  which would have been due on May 27, 1995, was
converted into 320,000 shares of Common Stock.

Also, during the 1995 period, $3.0 million of the debentures issued in May 1995,
along with $34,000 of accrued  interest,  were  converted into 507,678 shares of
Common Stock net of unamortized debt issuance costs totaling $211,000.

During 1996, an additional $3.3 million of the  debentures,  along with $258,000
of accrued  interest,  were converted into 612,061 shares of Common Stock net of
unamortized debt issuance costs totaling $111,000.


                                       19
<PAGE>


During 1997,  $425,000 of outstanding  debentures along with $139,000 of accrued
interest were  converted  into 98,267 shares of Common Stock net of  unamortized
debt issuance costs totaling  $1,000.  In addition,  419 shares of Embrex Common
Stock were issued pursuant to the non-cash  exercise of warrants  related to the
initial  sale of the  debentures  in May  1995.  As of  December  1,  1997,  all
debentures had been converted into Common Stock.

On May 27,  1997,  34,320  shares of Common  Stock were issued in  exchange  for
substantially all of the assets of Agrimatic Corporation.

Consolidated Statements of Shareholders' Equity

(Dollars in thousands)

<TABLE>
<CAPTION>
                                                                             Additional      Currency
                                                                Common        Paid-in       Translation    Accumulated
                                                                 Stock        Capital       Adjustments      Deficit         Total
                                                               --------      ----------     -----------    -----------     --------
<S>                                                            <C>            <C>            <C>            <C>            <C>     
Balance at December 31, 1994 .............................     $ 41,624       $    221       $      0       $(36,522)      $  5,323
                                                               --------       --------       --------       --------       --------
     Stock issued:
         Upon exercise of options ........................          134                                                         134
         Under employee stock purchase plan ..............           80                                                          80
         Upon conversion of long-term debt
              (net of issuance costs of $232) ............        3,554            450                                        4,004
         Upon exercise of warrants .......................          730                                                         730
     Warrants issued on May 1, 1995 ......................                         150                                          150
     Net loss ............................................                                                    (4,512)        (4,512)
                                                               --------       --------       --------       --------       --------
Balance at December 31, 1995 (as restated) ...............       46,122            821              0        (41,034)         5,909
     Stock issued:
         Upon exercise of options ........................          286                                                         286
         Under employee stock purchase plan ..............           68                                                          68
         Upon conversion of long-term debt
              (net of issuance cost of $1) ...............        2,947            494                                        3,441
         Upon exercise of warrants .......................        3,084                                                       3,084
         Establishment of $.01 par value
                (Note 6) .................................      (52,427)        52,427
     Currency translation adjustments ....................                                        180                           180
     Net income ..........................................                                                       341            341
                                                               --------       --------       --------       --------       --------
Balance at December 31, 1996 .............................           80         53,742            180        (40,693)        13,309
     Stock issued:
         Upon exercise of options ........................            1            201                                          202
         Under employee stock purchase plan ..............                          55                                           55
         Upon conversion of long-term debt
              (net of issuance costs of $111) ............            1            563                                          564
         Upon issuance of shares for
              Agrimatic acquisition ......................                         227                                          227
     Currency translation adjustments ....................                                       (376)                         (376)
     Net income ..........................................                                                     1,760          1,760
                                                               --------       --------       --------       --------       --------
Balance at December 31, 1997 .............................     $     82       $ 54,788       $   (196)      $ 38,933       $ 15,741
                                                               ========       ========       ========       ========       ========
</TABLE>



                                       20
<PAGE>


Notes to Consolidated Financial Statements

1.   Significant Accounting Policies

Nature of Business

Embrex,  Inc. has  developed  and  commercialized  the  INOVOJECT(R)  system,  a
proprietary,  automated,  in-the-egg  injection system which eliminates the need
for manual vaccination of newly hatched broiler chicks. Embrex also develops and
markets patented  pharmaceutical and biological products to improve bird health,
reduce bird  production  costs and provide  economic value to the global poultry
industry.

Acquisition

On May 27, 1997,  the Company  issued  34,320 shares of Common Stock in exchange
for substantially all of the assets of Agrimatic  Corporation.  This transaction
had an immaterial effect on the operations of Embrex.

Principles of Consolidation

The consolidated  financial  statements include the accounts of Embrex, Inc. and
its wholly owned subsidiaries, Embrex Europe Limited and Embrex Sales, Inc. (the
"Company").  All significant  intercompany  transactions  and accounts have been
eliminated.  Currently,  foreign  operations  account  for less  than 10% of the
Company's revenues.

Cash and Cash Equivalents

The Company  considers  all highly liquid  investments  with a maturity of three
months or less when purchased to be cash equivalents.

Inventories

Items recorded as inventory are generally  purchased from others and recorded at
the lower of cost or  market  using  the  average  cost  method.  Materials  and
supplies inventories include spare parts for the INOVOJECT(R) systems as well as
laboratory and general supplies. Product inventories are comprised of biological
compounds, principally the Company's viral neutralizing factor product (VNF(R)).

INOVOJECT(R) Systems

INOVOJECT(R)  systems are  comprised  of egg  injection  and  related  equipment
available for lease to customers. The equipment is recorded at the lower of cost
or estimated net realizable value. Depreciation is computed principally by using
accelerated  methods  over  the  estimated  useful  life  of the  equipment  and
commences after construction is complete and the equipment is placed in service.

Equipment, Furniture and Fixtures

Equipment, furniture and fixtures are recorded at cost. Depreciation is computed
principally by using accelerated  methods over the estimated useful lives of the
assets placed in service.

Patents and Exclusive Licenses of Patentable Technology

Costs incurred to acquire exclusive licenses of U.S.  patentable  technology and
to apply for and obtain U.S.  patents on  internally  developed  technology  are
capitalized  and amortized using the  straight-line  method.  Exclusive  license
agreements are amortized  over the period of the license.  Patents are amortized
over the shorter of the useful or legal life of the patent.


                                       21
<PAGE>


Foreign Currency Translation

All  assets and  liabilities  in the  balance  sheets of the  Company's  foreign
subsidiary,  Embrex Europe Limited, and its Asian operations,  are translated at
year-end  exchange  rates except  shareholders'  equity which is  translated  at
historical rates. Revenues,  costs and expenses are recorded at average rates of
exchange  during the year.  Translation  gains and losses are  accumulated  as a
component of shareholders' equity. Foreign currency transaction gains and losses
are included in determining net income.

Revenue Recognition

INOVOJECT(R)  system  fees are  recognized  based on eggs  processed  during the
period.  Product sales are  recognized  when the products are shipped.  Contract
research  revenue is  recognized on a  straight-line  basis over the term of the
contract.  Revenue  received,  but not yet  earned,  is  classified  as deferred
revenue.

Research and Development Costs

Research and development  costs,  including costs incurred to complete  contract
research,  are charged to operations when incurred and are included in operating
expenses.

Income Taxes

The Company accounts for income taxes under the provisions of Statement of
Financial Accounting Standards No. 109, "Accounting for Income Taxes" (SFAS
109). SFAS 109 requires recognition of deferred tax assets and liabilities for
the expected future tax consequences of temporary basis differences that have
arisen between financial statement and income tax reporting.

Net Income (Loss) Per Share

In February  1997, the Financial  Accounting  Standards  Board  ("FASB")  issued
Statement  No. 128,  "Earnings  per Share" which  established  new standards for
computing and  presenting  net income per share  information.  As required,  the
Company  adopted  the  provisions  of  Statement  No. 128 in its 1997  financial
statements  and has  restated  all prior year net income per share  information.
Basic net income per share was  determined by dividing net income  available for
common  shareholders by the weighted average number of common shares outstanding
during each year.  Diluted net income per share reflects the potential  dilution
that could occur assuming  conversion or exercise of all convertible  securities
and issued and unexercised  stock options.  A  reconciliation  of the net income
available for common  shareholders  and number of shares used in computing basic
and diluted net income per share is in Note 13.

Use of Estimates

The presentation of financial  statements in conformity with generally  accepted
accounting principles requires management to make estimates and assumptions that
affect the amounts reported in the financial  statements and accompanying notes.
Actual results could differ from these estimates.

Principal Customers

Tyson  Foods,  Inc.   ("Tyson")   accounted  for  approximately  28  percent  of
consolidated  1997  revenues.  Based on the  millions of pounds of  ready-to-eat
poultry meat produced in 1997,  Tyson accounted for  approximately 26 percent of
the  broilers  grown  in the U.S.  In 1997,  Tyson  was the only  customer  that
represented greater than 10 percent of total revenues.

Concentration of Credit Risk

The Company's principal financial instrument, subject to potential concentration
of credit  risk,  is accounts  receivable  which are  unsecured.  The  Company's
exposure  to  credit  loss in the  event  payment  is not  received  equals  the
outstanding  accounts  receivable balance. As of December 31, 1997, Tyson Foods,
Inc. accounted for approximately



                                       22
<PAGE>


23% of consolidated accounts receivable,  and substantially all of the Company's
accounts receivable are due from companies in the poultry industry.

Sources of Supply

The  Company  has  developed a  strategic  relationship  with a single  contract
manufacturer  to  fabricate  its  INOVOJECT(R)  systems.   While  other  machine
fabricators exist and have constructed limited numbers of INOVOJECT(R)  systems,
a change in  fabricators  could  cause a delay in  manufacturing  and a possible
delay in the timing of future INOVOJECT(R) installations and revenues from those
installations.

The Company has granted Select Laboratories,  Inc.  ("Select"),  a subsidiary of
Rhone  Merieux SA,  exclusive  rights to  manufacture  bursal  disease  vaccines
containing  Embrex's  proprietary  VNF(R)  product for Embrex to market in North
America,  Latin  America and Asia under the trade name  Bursaplex(TM).  In 1995,
Embrex  granted  Cyanamid  Websters  ("Websters"),  a unit of Ft.  Dodge  Animal
Health, which is a division of American Home Products Corp., exclusive rights to
manufacture and market bursal disease  vaccines  containing the Company's VNF(R)
product to be  marketed in Europe,  the Middle  East and Africa  under the trade
name Bursamune(TM).  Additionally,  the Company has one contract supplier of its
VNF(R) product. The manufacture of the bursal disease vaccines being produced by
Select and Websters and the Company's VNF(R) product generally must be performed
in licensed facilities and/or under regulatory approved methods.  Although there
are other manufacturers who are capable of manufacturing bursal disease products
and producing  products such as VNF(R),  a change of suppliers  could  adversely
effect the Company's  future  operating  results due to the time it would take a
new supplier to obtain  regulatory  approval of its  production  process  and/or
manufacturing  facilities.  The Company seeks to minimize this exposure  through
multi-year supply agreements and the maintenance of adequate inventories.

Reclassification

Certain 1997, 1996, and 1995 amounts in the accompanying financial statements
have been reclassified to conform to the presentation adopted in the fourth
quarter of 1996 and during 1997. These reclassifications had no effect on
previously reported net income or loss or shareholders' equity in 1995, 1996 or
1997.

Impact of Recently Issued Accounting Standards

In 1997, the FASB issued Statements No. 130,  "Reporting  Comprehensive  Income"
("SFAS  130") and No. 131,  "Disclosures  About  Segments of an  Enterprise  and
Related  Information"  ("SFAS 131"),  which are both  effective for fiscal years
beginning after December 15, 1997. SFAS 130 addresses reporting amounts of other
comprehensive income and SFAS 131 addresses reporting segment  information.  The
Company does not believe that the  adoption of these new  standards  will have a
material impact on its financial statements.

2.   Restricted Cash

On October  13,  1997,  the  Company  executed a ten-year  collateralized  lease
relative  to the  facilities  housing the  Company's  new  research  and testing
facility.  Such collateral exists in the form of a certificate of deposit, which
is required to be maintained at least through the end of the seventh year of the
lease.

3.   Short-Term Investments

Management determines the appropriate  classification of its investments in debt
securities at the time of purchase and reevaluates  such  determination  at each
balance sheet date.  Debt  securities  for which the Company has both the intent
and  ability to hold to  maturity  are  classified  as held to  maturity.  These
securities are carried at amortized  cost. At December 31, 1997, the Company had
no investments that qualified as trading or available for sale.



                                       23
<PAGE>


At  December  31,  1996,  the  Company's  investments  in debt  securities  were
classified as cash and cash equivalents and short-term investments.  The Company
maintains cash and cash  equivalents and short-term  investments  principally of
United States treasury securities and commercial paper with a maturity date less
than twelve months with various  financial  institutions.  The Company  performs
periodic  evaluations  of  the  relative  credit  standing  of  those  financial
institutions that are considered in the Company's  investment  strategy which is
designed to limit exposure to any one institution.

At December 31, 1997,  the Company held no short-term  investments.  At year-end
1996,  the Company  held  short-term  investments  totaling  $876,000,  of which
$251,000 was held in commercial paper, and $625,000 in repurchase agreements.

The  Company's  short-term  investment  balances are  maintained  in accounts at
various financial  institutions.  In connection with the secured line of credit,
the Company has  deposited  $298,000 as a  compensating  cash  balance  with the
lender.

4.   Leases

At December 31, 1997 and 1996, the Company had assets totaling $14.0 million and
$13.9 million,  respectively,  financed by capital lease agreements which expire
through October 2000.  Accumulated  depreciation and amortization includes $10.1
million and $8.2 million of amortization related to these assets at December 31,
1997 and 1996,  respectively.  Amortization of assets financed by capital leases
is included with depreciation  expense. As of December 31, 1996, the Company has
used $9.2  million  ($0 in 1997 and $2.1  million in 1996) of the $11.2  million
capital lease  financing  closed in 1995 to fund  construction  of  INOVOJECT(R)
systems  principally under contract with North American  customers in the United
States.  At  December  31,  1996,  the  Company had  available  $2.0  million of
aggregate  unutilized  capital financing capacity for use in the construction of
INOVOJECT(R) systems. This unused commitment expired in June 1997.

The Company leases its facilities  under a number of operating  leases extending
through  November 2007. The Company has the option to cancel the operating lease
agreement  with the  payment  of a $180,000  penalty.  Total  rent  expense  was
$312,000,  $334,000,  and $426,000 for the years ended December 31, 1997,  1996,
and 1995, respectively.

At December 31, 1997, the Company's minimum future commitments under capital and
operating leases were as follows:

<TABLE>
<CAPTION>
                                                                               Operating          Capital
                                                                                Leases            Leases
                                                                                ------            ------
<S>                                                                           <C>               <C>       
1998...................................................................       $  407,000        $3,018,000
1999...................................................................          351,000         2,940,000
2000...................................................................          337,000           637,000
2001...................................................................          346,000                 0
2002...................................................................          185,000                 0
Beyond.................................................................          696,000                 0
                                                                              ----------        ----------

Total..................................................................       $2,322,000        $6,595,000
                                                                              ==========
Less amounts representing interest...........................................................     (935,000)
                                                                                                ----------
Present value of future minimum lease payments...............................................   $5,660,000
                                                                                                ==========
</TABLE>

5.   Long-Term Debt

During 1997,  $425,000 of outstanding  debentures  along with $66,000 of accrued
interest were  converted  into 98,267 shares of Common Stock net of  unamortized
debt issuance costs totaling  $1,000.  In addition,  419 shares of Embrex Common
Stock were issued pursuant to the non-cash  exercise of warrants  related to the
initial sale of such debentures.

On  May  1,  1995,  the  Company  closed  on a  private  placement  offering  of
convertible  debentures  ("the  debentures")  resulting  in net  proceeds to the
Company of $5.4  million  (as  adjusted  for the August 1995  rescission  of the
issuance of $225,000 of the  debentures).  The debentures were payable on May 1,
1997.  Through June 13, 1995,  the holders of the  debentures  were  entitled to
convert the  debentures  into Common Stock of the Company at a conversion  price
equal to



                                       24
<PAGE>


the average  market price at the time of issuance.  Commencing on June 14, 1995,
the holders of the  debentures  were  entitled to convert  the  debentures  into
Common  Stock of the Company at a  conversion  price of the lesser of the market
price at the time of  issuance  ($5.00 per  share) or 85 percent of the  average
closing bid price of the Company's Common Stock for the five trading days ending
on the conversion date. The debentures accrued interest, payable at maturity, at
a rate of 8 percent per annum.  The accrued interest was convertible into Common
Stock of the Company at the same  conversion  price as the debenture  principal.
The Company had the right to demand conversion of the debentures and any accrued
interest  after April 30, 1996.  Additionally,  at any time, the Company had the
right to  redeem  the  debentures  for  cash  equal  to the  closing  bid of the
Company's  Common Stock at the date of redemption  multiplied by the  underlying
shares into which the  debentures  would have been  convertible.  In conjunction
with this offering,  the Company incurred  issuance costs totaling  $540,000 and
recorded  $1.0  million of interest  expense  related to the 15%  discount  from
market upon  conversion  (See Note 12). The issuance  costs were  amortized as a
component of interest expense over the term of the debentures.

In 1995,  $3.0 million of the  debentures'  principal  and related  discount was
converted into 517,910 shares of Common Stock,  net of unamortized debt issuance
costs totaling $215,000.  During 1996, an additional $3.3 million debentures and
related  discount,  along with $258,000 of accrued  interest were converted into
612,061 shares of Common Stock,  net of unamortized debt issuance costs totaling
$111,000.

As part of its  compensation  for the sale of the  convertible  debentures,  the
Company's placement agent received a 6.5 percent  commission,  which is included
in the $540,000 total issuance costs,  and warrants to purchase 96,000 shares of
Common  Stock  at a price of  $6.00  per  share.  The  estimated  value of these
warrants, $150,600, has been recorded as additional paid-in capital, while their
cost was included within the $540,000 total issuance costs discussed above.

On May 29,  1991,  the  Company  issued a four-year  convertible  term note (the
"note") to American Cyanamid Company, now a subsidiary of American Home Products
Corporation,  in exchange for $1.2 million.  During May 1995, at the election of
American Cyanamid, the note was converted into 320,000 shares of Common Stock of
the Company.  Contemporaneous with the conversion,  the Company paid to American
Cyanamid $160,000 of accrued interest due on the note.

6.   Shareholders' Equity

On May 16, 1996, the Company's  shareholders  approved an increase in the number
of authorized shares of Common Stock from 15,000,000 to 30,000,000 shares and an
increase in the amount of authorized  Preferred  Stock from 20,000 to 15,000,000
shares.  In addition,  the Company changed the par value of the Common Stock and
Series A  Participating  Preferred  Stock from no par value to par value  stock,
with a par value of $.01 per share.

At December  31, 1997,  the Company had reserved a total of 1,840,382  shares of
its Common Stock for future issuance as follows:

For exercise of warrants to purchase Common Stock.................       390,775
For exercise of Common Stock options..............................     1,396,300
For possible future issuance to employees and others
under employee stock purchase plans...............................        53,307
                                                                       ---------

Total reserved.....................................................    1,840,382
                                                                       =========



                                       25
<PAGE>


At  December  31,  1997,  the  Company  had issued and  outstanding  warrants to
purchase Common Stock as follows:

                                                                 Date through
    Exercise Price                  Shares Reserved for         Which Warrants
      Per Share                     Exercise of Warrants       are Exercisable
    --------------                  --------------------       ---------------
    $8.07....................             188,197                  7/28/98
    $9.02....................              31,578                  1/28/99
    $9.50....................              30,000                 12/31/00
    $9.50....................              15,000                   6/9/01
    $6.00....................              96,000                  4/30/00
    $7.28....................              30,000                 10/30/01
                                          -------
                                          390,775
                                          =======

7.   Stock Option Plans

The Company's stock option plans provide for option grants  designated as either
nonqualified  or incentive  stock  options.  The options  generally  vest over a
four-year  period and expire ten years from the date of grant.  In general,  the
exercise  price of stock options is the closing  price of the  Company's  Common
Stock on the date of grant.

Most U.S.  employees  and certain  employees  outside the U.S.  are  eligible to
receive  a grant  of  stock  options  periodically  with the  number  of  shares
generally  determined by the employee's  salary grade and performance  level. In
addition,  certain  management and  professional  level  employees may receive a
stock option  grant upon hire.  Non-employee  directors  of the Company  receive
annual grants of stock options in amounts specified in the applicable plan.

Stock option information with respect to all of the Company's stock option plans
follows:

<TABLE>
<CAPTION>
                                                                      Number                 Option Price Range         Expiration
                                                                     of Shares                   per Share                 Date
                                                                     ---------               ------------------         ----------
<S>                                                                 <C>                       <C>      <C>               <C>  <C> 
Balance at December 31, 1994, outstanding options..................   713,402                 $2.00 to $8.75             1998-2004
     Granted.......................................................   314,370                 $5.875 to $6.50                 2005
     Exercised.....................................................   (59,444)                $2.00 to $7.875 
     Canceled......................................................   (59,207)                $2.00 to $8.75
                                                                    ---------

Balance at December 31, 1995, outstanding options..................   909,121                 $2.00 to $8.375            1998-2005
     Granted.......................................................   111,980                 $6.125 to $7.625                2006
     Exercised.....................................................   (66,873)                $2.00 to $7.00
     Canceled......................................................   (87,814)                $6.125 to $2.00
                                                                    --------

Balance at December 31, 1996, outstanding options..................   866,414                 $2.00 to $8.375            1998-2006
     Granted.......................................................   279,525                 $6.063 to $7.125                2007
     Exercised.....................................................   (53,779)                $2.00 to $7.00
     Canceled......................................................   (53,568)                $6.125 to $7.00
                                                                    ---------

Balance at December 31, 1997, outstanding options.................. 1,038,592                 $2.00 to $8.75             1998-2007
                                                                    =========
</TABLE>

At December 31, 1997,  options to purchase 1,038,592 shares of Common Stock were
exercisable at prices ranging from $2.00 to $8.375 per share.

The Company has elected to follow  Accounting  Principles  Board  Option No. 25,
"Accounting for Stock Issued to Employees" (APB 25) and related  Interpretations
in accounting for its employee stock options  because,  as discussed  below, the
alternative  fair value  accounting  provided for under FASB  Statement No. 123,
"Accounting  for  Stock-Based  Compensation,"  requires use of option  valuation
models that were not developed for use in valuing employee stock options.  Under
APB 25,  because the exercise  price of the  Company's  employee  stock  options
equals  the  market  price of the  underlying  stock on the  date of  grant,  no
compensation expense is recognized.



                                       26
<PAGE>


The Company's 1996  Amendment to its 1993 Incentive  Stock Option Plan increases
the  authorized  grant of options to company  personnel  from 500,000  shares of
common stock up to 1.2 million  shares.  All options  granted have 10 year terms
and  vest  and  become  fully  exercisable  at the end of 4 years  of  continued
employment.

Pro forma  information  regarding  net income  (loss) and  income  (loss)  per
share is  required  by SFAS  123,  and has  been  determined  as if the  Company
accounted for its employee stock options granted subsequent to December 31, 1994
under the fair value  method of SFAS 123.  The fair value for these  options was
estimated at the date of grant using a  Black-Scholes  option pricing model with
the following weighted average assumptions:

                                                1997          1996         1995
                                                -----         -----        ----
      Risk free interest rate...............    6.13          6.42         6.13
      Dividends...........................       --            --           --
      Volatility factor...................      0.358         0.421        0.358

The Black-Scholes option valuation model was developed for use in estimating the
fair value of traded  options which have no vesting  restrictions  and are fully
transferable.  In addition,  option valuation models require the input of highly
subjective  assumptions  including the expected stock price volatility.  Because
changes in the subjective input assumptions can materially affect the fair value
estimate,  in  management's  opinion,  the  existing  models do not  necessarily
provide a  reliable  single  measure  of the fair  value of its  employee  stock
options.

For purposes of pro forma  disclosures,  the estimated fair value of the options
is amortized to expense over the options'  vesting  period.  The  Company's  pro
forma information follows:

<TABLE>
<CAPTION>
                                                            For the year ended December 31
                                                     --------------------------------------------
                                                        1997                  1996                   1995
                                                        -----                 -----                  ----
<S>                                                   <C>                    <C>                 <C>
Pro forma net income (loss).......................    $1,241,310             $51,513             $(4,574,000)
Pro forma income (loss) per share.................    $     0.15             $  0.01             $     (0.72)
</TABLE>


Exercise  prices for options  outstanding  as of  December  31, 1997 ranged from
$2.00 to $8.75.

The weighted average remaining  contractual life of those options is 8.42 years.
The weighted average  exercisable  price of outstanding  options at December 31,
1996 is $6.52.

8.   Employee Stock Purchase Plan

The Company has an Employee Stock Purchase Plan (the "Purchase Plan") to provide
its employees  with an additional  opportunity  to share in the ownership of the
Company.  Under terms of the Purchase Plan, all regular  full-time  employees of
the Company may make voluntary  payroll  contributions  thereby enabling them to
purchase Common Stock at a price to be determined by the Compensation  Committee
of the Board, but not less than 85 percent of the lower of the fair market value
as of the beginning or end of the twelve-month  offering  period.  Contributions
are limited to 20 percent of an employee's compensation. Up to 100,000 shares of
Common Stock may be issued under the Purchase Plan.

Under the Purchase Plan, during 1997, 1996 and 1995, 9,764,  11,028,  and 17,041
shares of Common Stock, respectively, were purchased.

9.   401(k) Retirement Savings Plan

The Company has a 401(k) plan which covers all employees upon employment who are
at least 18 years of age. Employer contributions are voluntary at the discretion
of the Company. There were no Company contributions for the years ended December
31, 1997, 1996, and 1995.



                                       27
<PAGE>


10.  Income Taxes

The components of income tax expense for the year ended December 31, 1997 are as
follows:

     Current:
        Federal....................................................    $ 59,000
        State......................................................      84,000
        Foreign....................................................     279,000
                                                                       --------
                                                                       $422,000
                                                                       ========

The Company's  consolidated  effective tax rate differed from the statutory rate
as set forth below for the year ended December 31, 1997:

     Federal taxes at statutory rate...............................    $742,000
     State and local income taxes, net of Federal benefit..........      84,000
     Non-deductible expenses.......................................      24,000
     Foreign losses for which no benefit has been recognized.......     346,000
     Change in valuation allowance.................................     125,000
     Utilization of net operating loss carryforwards...............  (1,238,000)
     Alternative minimum and foreign withholding taxes.............     338,000
     Other.........................................................       1,000
                                                                     ----------
                                                                       $422,000
                                                                     ==========

Deferred income taxes reflect the net effects of temporary  differences  between
the carrying amounts of assets and liabilities for financial  reporting purposes
and the amounts  used for income tax  purposes.  The Company has no deferred tax
liabilities.  Significant components of the Company's deferred tax assets are as
follows:

<TABLE>
<CAPTION>
                                                                                           At December 31,
                                                                                  --------------------------------
                                                                                      1997                 1996
                                                                                  -----------          -----------
<S>                                                                               <C>                  <C>
     Deferred tax assets:
          Book over tax depreciation........................................         $718,000             $790,000
          Net operating loss carryforwards..................................       11,430,000           12,800,000
          Research and experimental tax credit carryforwards................        1,915,000            1,725,000
          Charitable contributions carryfoward..............................           16,000               16,000
          Other.............................................................          158,000              170,000
                                                                                  -----------          -----------
              Total deferred tax assets.....................................       14,237,000           15,501,000
     Valuation allowance for deferred tax assets............................      (14,237,000)         (15,501,000)
                                                                                  -----------          -----------
          Net deferred tax assets...........................................               $0                   $0
                                                                                           ==                   ==
</TABLE>

During 1997 and 1996,  the valuation  allowance  decreased by  ($1,264,000)  and
($255,000), respectively.

At December 31,  1997,  the Company had net  operating  loss  carryforwards  for
federal income tax purposes of approximately  $34 million which are available to
offset future  taxable  income.  These net operating loss  carryforwards  expire
during the years 2000  through  2010.  As a result of the  changes in  ownership
percentages  which occurred with the 1991 Initial  Public  Offering  (IPO),  the
future utilization of the net operating loss carryforwards incurred prior to the
1991  IPO  is  limited  to  approximately   $2.1  million  per  year.  Any  loss
carryforward  amounts  exceeding the limitation can be carried forward to future
years within the  carryforward  period.  The net  operating  loss  carryforwards
incurred subsequent to the 1991 IPO are not subject to these change in ownership
limitations.

In addition,  the Company has Research and Experimental Tax Credit carryforwards
totaling approximately $1.9 million which are available to offset future federal
income taxes. These credits expire during the years 2000 through 2012.



                                       28
<PAGE>


11.  Commitments

As of December 31, 1997,  the Company had  outstanding  purchase  commitments of
approximately   $2.5  million   related  to  the  production  of  the  Company's
Bursaplex(TM)  product,  and  materials  and supplies for the  construction  and
maintenance of INOVOJECT(R) egg injection systems.

12.  Restatement

At the annual meeting of the American  Institute of Certified Public Accountants
(AICPA) in January  1997 and at the March  1997  staff  meeting of the  Emerging
Issues  Task Force of the  Financial  Accounting  Standards  Board  (FASB),  the
Securities  and  Exchange  Commission  staff  stated  that a charge to income is
appropriate  in  situations  where  a  registrant  has  issued  debt  securities
convertible to Common Stock at the lower of a conversion  rate fixed at issuance
or a  fixed  discount  to  the  Common  Stock's  market  price  at the  date  of
conversion.

In  accordance  with the SEC's  position,  the  Company  has  restated  its 1995
financial  statements  to record  additional  interest  expense of $1.1  million
related  to the  conversion  feature  at a 15%  discount  included  in the  1995
debentures (see Note 4). The restatement resulted in an increase of $1.0 million
in the  previously  reported  1995 net loss and an increase in 1995 net loss per
share from $.57 per share to $.73 per share. In addition,  at December 31, 1995,
long-term debt was increased by $569,000 and  shareholders  equity was decreased
by $569,000 to reflect the conversion discount related to outstanding debentures
that had not been converted.



                                       29
<PAGE>


13.  Net Income (Loss) Per Share

The following  table sets forth the  computation of basic and diluted net income
(loss) per share (in thousands, except per share amounts):

                                                      1997      1996      1995
                                                    -------   -------   -------
Numerator:
     Net Income (Loss) Available To
     Common Stockholders ........................   $ 1,760   $   341   $(4,512)

     Effect of dilutive securities:
       Regulation S Debentures ..................         9       122      --
                                                    -------   -------   -------

         Numerator for diluted earnings
         per share-income available to
         common stockholders after
         assumed Conversions ....................   $ 1,769   $   463   $(4,512)
                                                    =======   =======   =======

Denominator:
     Denominator for basic net income per
     share--weighted-average shares .............     8,184     7,218     6,187

     Effect of Dilutive Securities:
         Employee Stock Options .................       143       188      --
         Warrants ...............................         8        12      --
         Convertible Debentures .................         4       102      --
                                                    -------   -------   -------
           Dilutive Potential Shares ............       155       302      --

         Denominator for diluted net income
         per share--adjusted weighted-
         average shares and assumed
         conversions ............................     8,339     7,520     6,187
                                                    =======   =======   =======


Basic net income per share ......................   $  0.21   $  0.05   $ (0.73)
                                                    =======   =======   =======

Diluted net income per share ....................   $  0.21   $  0.06   $ (0.73)
                                                    =======   =======   =======

ITEM 9.  CHANGES  IN  AND  DISAGREEMENTS  WITH  ACCOUNTANTS  ON  ACCOUNTING  AND
         FINANCIAL DISCLOSURE


Not applicable.


                                       30
<PAGE>


                                    PART III

ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

Information on the executive officers and directors is incorporated by reference
from  the  Company's  Proxy  Statement  (under  the  headings  "Management"  and
"Proposal I: Election of Directors,"  respectively),  with respect to the Annual
Meeting  of  Shareholders  to be held on May 21,  1998,  to be  filed  with  the
Securities and Exchange Commission.

ITEM 11. EXECUTIVE COMPENSATION

This information is incorporated by reference from the Company's Proxy Statement
(under the heading "Executive Compensation"), with respect to the Annual Meeting
of  Shareholders to be held on May 21, 1998, to be filed with the Securities and
Exchange Commission.

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

This information is incorporated by reference from the Company's Proxy Statement
(under the  heading  "Share  Ownership  of  Management  and  Certain  Beneficial
Owners"),  with respect to the Annual Meeting of  Shareholders to be held on May
21, 1998, to be filed with the Securities and Exchange Commission.

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

Not applicable.


                                       31
<PAGE>


                                     PART IV

ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K

     (a)(1).  The  financial  statements  listed below are included in Item 8 of
     this report.  All financial  statement  schedules  normally  required under
     Regulation S-X are omitted as the required information is inapplicable.

Report of Independent Auditors

Financial Statements

Consolidated Balance Sheets at
December 31, 1996 and 1997

Consolidated Statements of Operations
for each of the three fiscal years ended
December 31, 1995, 1996 and 1997

Consolidated Statements of Cash Flows
for each of the three fiscal years ended
December 31, 1995, 1996 and 1997

Consolidated Statements of Shareholders'
Equity for each of the three fiscal
years ended December 31, 1995, 1996 and 1997

Notes to Consolidated Financial Statements

     (a)(2).  The financial  statements of the Company's Employee Stock Purchase
     Plan  listed  below are filed  herewith,  pursuant  to Form  10-K,  General
     Instruction F.

Report of Independent Auditors

Financial Statements

Statements of Net Assets Available for Plan
Benefits at December 31, 1996 and 1997

Statements of Changes in Net Assets Available
for Plan Benefits for the three years ended
December 31, 1997

Notes to Financial Statements


                                       32
<PAGE>


     (a)(3).  The  exhibits  listed  below  are  filed  as part of this  report.
     Executive  compensation plans and arrangements are listed in Exhibits 10.14
     through 10.32.


Exhibits                    Description
- --------                    -----------
3.1(1)                      Restated Articles of Incorporation

3.2(2)                      Articles  of  Amendment  to  Restated   Articles  of
                            Incorporation, effective March 21, 1996

3.3(3)                      Articles  of  Amendment  to  Restated   Articles  of
                            Incorporation, effective May 28, 1996

3.4                         Amended and  Restated  Bylaws,  effective  March 27,
                            1998

4.1                         Reference is made to Exhibits 3.1, 3.2, 3.3 and 3.4

4.2(4)                      Specimen of Common Stock Certificate

4.3(5)                      Notices to holders of outstanding warrants regarding
                            adjustments   in  warrant   terms   resulting   from
                            Regulation S private placement

4.4(6)                      Form of Registration Rights Agreement

4.5(5)                      Form  of   Regulation  S   Securities   Subscription
                            Agreement

4.6(5)                      Form of Embrex 8%  Convertible  Debenture due May 1,
                            1997

4.7(5)                      Warrant to Purchase Common Stock of Embrex issued to
                            Schwartz Investments, Inc.

4.8(7)                      Rights  Agreement dated as of March 21, 1996 between
                            Embrex  and Branch  Banking  and Trust  Company,  as
                            Rights Agent

10.1(8)                     Exchange  Agreement  dated  May  28,  1991,  between
                            Embrex and American Cyanamid  Company,  Advent First
                            Limited  Partnership A,  Biotechnology  Venture Fund
                            S.A.,  Biotechnology   Investments  Limited,  Domain
                            Partners,  L.P.,  Elf  Technologies,   Inc.,  Prince
                            Venture    Partners   III,   L.P.,   3I   Securities
                            Corporation, and Charles E. Austin

10.2(8)                     Form of Stock Purchase  Warrant  exercisable for the
                            purchase of 180,003 shares of Common Stock

10.3(8)                     License  Agreement dated December 11, 1991,  between
                            Embrex  and  the  National   Technical   Information
                            Service,  a  primary  operating  unit of the  United
                            States Department of Commerce

10.4(8)                     Collaborative  Research  Agreement dated January 17,
                            1989 between Embrex and the University of Arkansas

10.5(8)                     License  Agreement  dated  October 1, 1988,  between
                            Embrex  and  the  National   Technical   Information
                            Service,  a  primary  operating  unit of the  United
                            States Department of Commerce

10.6(8)                     Lease  Agreement  dated  December  9,  1986  between
                            Embrex, as tenant,  and Imperial Center  Partnership
                            and Petula Associates, Ltd., as landlord, as amended
                            by  First  Amendment  dated  June 11,  1987,  Second
                            Amendment   dated   December  1,  1988,   and  Third
                            Amendment dated May 2, 1989


                                       33
<PAGE>


Exhibits                    Description
- --------                    -----------

10.7(4)                     Fourth  Amendment  of Lease  dated  October  1, 1994
                            between the Company and Glaxo Inc. (as  successor in
                            interest to Imperial  Center  Partnership and Petula
                            Associates, Ltd.)

10.8(4)                     Fifth  Amendment  of Lease dated  December  13, 1996
                            between  the  Company and Glaxo  Wellcome  Inc.  (as
                            successor in interest to Glaxo Inc.)

10.9                        Lease for Royal  Center II dated  October  13,  1997
                            between the Company and Petula Associates, Ltd.

10.10(8)                    Facility  Agreement  dated  March 1,  1991,  between
                            Embrex  and  Mississippi  Agriculture  and  Forestry
                            Experiment Station, Mississippi State University

10.11(8)                    Unrestricted  Grant  Agreement  dated April 1, 1988,
                            between Embrex and North Carolina State  University,
                            as amended by Amendment dated September 15, 1989 and
                            Amendment dated April 22, 1991

10.12(8)                    Unrestricted Grant Agreement dated November 1, 1986,
                            between Embrex and North Carolina State  University,
                            as amended by Amendment dated May 3, 1989, Amendment
                            dated  September 15, 1989, and Amendment dated April
                            22, 1991

10.13(8)                    Basic  Research  Agreement  dated  October 24, 1989,
                            between  Embrex  and  University  of  Arkansas,   as
                            amended on October  23,  1990,  February 1, 1991 and
                            July 22, 1991

10.14(8)                    1988  Incentive   Stock  Option  Plan  and  form  of
                            Incentive Stock Option Agreement

10.15(8)                    1989  Nonstatutory  Stock  Option  Plan  and form of
                            Nonstatutory Stock Option Agreement

10.16(8)                    1991  Nonstatutory  Stock  Option  Plan  and form of
                            Nonstatutory Stock Option Agreement

10.17(9)                    Incentive Stock Option and Nonstatutory Stock Option
                            Plan and  forms of Stock  Option  Agreements  - June
                            1993

10.18(3)                    Amendment  dated  May 16,  1996 to  Incentive  Stock
                            Option and  Nonstatutory  Stock  Option  Plan - June
                            1993

10.19(4)                    Amended and Restated Employee Stock Purchase Plan

10.20(8)                    Employment   Agreement   dated  November  15,  1989,
                            between Embrex and Randall L. Marcuson

10.21(4)                    Amendment to Employment Agreement dated May 21, 1996
                            between Embrex and Randall L. Marcuson

10.22(4)                    Change In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Randall L. Marcuson

10.23(8)                    Employment Agreement dated October 16, 1989, between
                            Embrex and Catherine A. Ricks

10.24(4)                    Change In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Catherine A. Ricks

10.25(2)                    General  Provisions to Employment  Agreement between
                            Embrex and Brian V. Cosgriff dated August 18, 1995


                                       34
<PAGE>


Exhibits                    Description
- --------                    -----------

10.26(4)                    Charge In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Brian V. Cosgriff

10.27(2)                    Terms and  Conditions of Employment  between  Embrex
                            Europe  Limited  and David M.  Baines  dated May 12,
                            1994

10.28(4)                    Change In Control Severance  Agreement dated June 9,
                            1996 between Embrex and David M. Baines

10.29(4)                    Letter   Agreement   and   General   Provisions   to
                            Employment  Agreement  dated August 20, 1996 between
                            Embrex  and  Don  T.   Seaquist  and   Amendment  to
                            Employment Agreement dated September 9, 1996 between
                            Embrex and Don T. Seaquist

10.30(4)                    Change  In   Control   Severance   Agreement   dated
                            September 9, 1996 between Embrex and Don T. Seaquist

10.31(4)                    Letter   Agreement   and   General   Provisions   to
                            Employment  Agreement  dated August 26, 1996 between
                            Embrex and Rick L. Ryan and  Amendment to Employment
                            Agreement  dated August 26, 1996 between  Embrex and
                            Rick L. Ryan

10.32(4)                    Change In Control  Severance  Agreement dated August
                            26, 1996 between Embrex and Rick L. Ryan

10.33(8)                    Shareholders' Agreement dated August 14, 1991 by and
                            among   Embrex,    Advent    Euroventures    Limited
                            Partnership,  and  Plant  Resource  Venture  Fund II
                            Limited Partnership

10.34                       INOVOJECT(R) Egg  Injection  System  Lease,  Limited
                            License,   Supply  and   Service   Agreement   dated
                            September  1, 1994  between  Embrex and Tyson Foods,
                            Inc.  (asterisks  located  within the exhibit denote
                            information  which has been  deleted  pursuant  to a
                            request for  confidential  treatment  filed with the
                            Securities and Exchange Commission)

10.35                       Amendment  dated March 26, 1997 to the  INOVOJECT(R)
                            Egg Injection System Lease, Limited License,  Supply
                            and  Service   Agreement  dated  September  1,  1994
                            between  Embrex  and Tyson  Foods,  Inc.  (asterisks
                            located within the exhibit denote  information which
                            has  been   deleted   pursuant   to  a  request  for
                            confidential treatment filed with the Securities and
                            Exchange Commission)

10.36(10)                   Master  Lease   Agreement  dated  December  3,  1993
                            between Embrex and Capital Associates International,
                            Inc.   with  a  form  of   equipment   schedule  and
                            collateral assignment of lease attached

10.37(10)                   Master  Lease   Agreement  dated  January  28,  1994
                            between  Embrex  and  Aberlyn   Capital   Management
                            Limited  Partnership  with a form of lease  schedule
                            and collateral assignment of lease attached

10.38(10)                   Agreement to Issue  Warrant  dated  January 28, 1994
                            between  Embrex  and  Aberlyn   Capital   Management
                            Limited Partnership

10.39(10)                   Common  Stock  Purchase  Warrant  issued to  Aberlyn
                            Capital Management Limited Partnership

10.40(10)                   Agreement to Issue  Warrant  dated  January 28, 1994
                            between Embrex and Aberlyn Holding Company, Inc.


                                       35
<PAGE>


Exhibits                    Description
- --------                    -----------

10.41(10)                   Common  Stock  Purchase  Warrant  issued to  Aberlyn
                            Holding Company, Inc.

10.42(11)                   Master   Equipment   Lease  Agreement  dated  as  of
                            December  7,  1994  between  Financing  for  Science
                            International,  Inc.  and  Embrex  with a Consent to
                            Assignment of Equipment  Lease  Agreement,  Security
                            Agreement and Rental Schedule attached

10.43(11)                   License  Agreement  dated  as of  December  7,  1994
                            between  Financing for Science  International,  Inc.
                            and Embrex with Sublicense Agreement attached

10.44(11)                   Common Stock Purchase Warrant dated January 17, 1995
                            issued to Financing for Science International, Inc.

10.45(11)                   Agreement  for Sale of  Equipment  and Rights  Under
                            User Agreement  dated as of December 7, 1994 between
                            Financing for Science International, Inc. and Embrex

10.46(5)                    Letter of  Agreement  for $6.0  million  Convertible
                            Regulation  S Private  Placement  by and between the
                            Company and Swartz  Investments,  Inc., as placement
                            agent

10.47(2)                    Limited  License  and Supply  Agreement  dated as of
                            July 20, 1995 between Embrex and Webster

10.48(4)                    Amendments  dated  August 1, 1996 and  November  11,
                            1996 to Limited  License and Supply  Agreement dated
                            as of July 20, 1995 between Embrex and Webster

10.49(2)                    Agreement  dated  as of  January  22,  1996  between
                            Embrex and Select

10.50(2)                    Letter  Agreement  dated  as  of  January  22,  1996
                            between Select and Embrex

10.51(2)                    License  dated as of  January  22,  1996  granted by
                            Select to Embrex

10.52(2)                    Commitment  letter  accepted  June 14, 1995  between
                            Embrex and Financing for Science International, Inc.
                            for $2.0 million capital lease financing facility

10.53(2)                    Stock Purchase  Warrant dated June 9, 1995 issued to
                            Financing for Science International, Inc.

10.54(2)                    Financing  Agreement  (Number  10783)  dated  as  of
                            October 30, 1995 between Lease Management  Services,
                            Inc. and Embrex,  and Addendum thereto dated October
                            30, 1995 attached

10.55(2)                    License  Agreement  dated  October 30, 1995  between
                            Embrex and Lease Management Services, Inc.

10.56(2)                    Sublicense  Agreement  dated as of October  30, 1995
                            between Embrex and Lease Management Services, Inc.

10.57(2)                    Movable Hypothec on Equipment and Contracts dated as
                            of  October  30,  1995  between   Embrex  and  Lease
                            Management Services, Inc.

10.58(2)                    Warrant to Purchase  30,000  Shares of Common  Stock
                            dated  October 30,  1995 issued to Lease  Management
                            Services, Inc.

10.59(2)                    Intercreditor Agreement dated as of October 31, 1995
                            among  Financing  for Science  International,  Inc.,
                            Lease Management Services, Inc., and Embrex.



                                       36
<PAGE>


Exhibits                    Description
- --------                    -----------

10.60(4)                    Embrex Europe Limited Loan Agreement  dated April 3,
                            1996

21                          Subsidiaries

23                          Consent  of Ernst & Young  LLP to the  inclusion  of
                            their report dated February 20, 1998 with respect to
                            the consolidated financial statements of the Company
                            in this Form 10-K and the incorporation by reference
                            of such report into the  Registration  Statement  on
                            Form  S-3  (No.   333-18231),   as  filed  with  the
                            Securities  and Exchange  Commission on December 19,
                            1996, and into the Registration Statements under the
                            Securities  Act of 1933 on  Form  S-8  (Registration
                            Nos.  33-51582,  33-63318 and  333-04109),  as filed
                            with  the  Securities  and  Exchange  Commission  on
                            September 1, 1992,  May 25, 1993,  and May 20, 1996,
                            respectively,  and to the incorporation by reference
                            in  the   Registration   Statement   on   Form   S-8
                            (Registration   No.  33-63318)   pertaining  to  the
                            Employee  Stock  Purchase Plan of their report dated
                            March  19,  1998  with  respect  to  the   financial
                            statements  of  the  Embrex,   Inc.  Employee  Stock
                            Purchase Plan included in this Form 10-K.

24                          Powers of Attorney

27.1                        Financial Data Schedule to the Company's Form 10-K
                            for the year ended December 31, 1997.

27.2                        Amended Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended March 31, 1997 as
                            filed with the Securities and Exchange Commission
                            on May 7, 1997.

27.3                        Amended and Restated Financial Data Schedule to the
                            Company's Form 10-K for the year ended December 31,
                            1996 as filed with the Securities and Exchange
                            Commission on March 31, 1997.

27.4                        Amended and Restated Financial Data Schedule to the
                            Company's Form 10-Q for the quarter ended September
                            30, 1996 as filed with the Securities and Exchange
                            Commission on November 30, 1996.

27.5                        Amended and Restated Financial Data Schedule to the
                            Company's Form 10-Q for the quarter ended June 30,
                            1996 as filed with the Securities and Exchange
                            Commission on August 12, 1996.

27.6                        Amended and Restated Financial Data Schedule to the
                            Company's Form 10-Q for the quarter ended March 31,
                            1996 as filed with the Securities and Exchange
                            Commission on May 13, 1996.

99                          Risk Factors relating to the Company

- ----------
     (1)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission  for fiscal  year  ending  December  31, 1991 and
          incorporated herein by reference

     (2)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1995 and
          incorporated herein by reference

     (3)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  June 30,  1996 and
          incorporated herein by reference

     (4)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission  for fiscal  year  ending  December  31, 1996 and
          incorporated herein by reference

     (5)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  June 30,  1995 and
          incorporated herein by reference

     (6)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  March 31, 1995 and
          incorporated herein by reference

     (7)  Exhibit to the Company's  Registration  Statement on Form 8-A as filed
          with the  Securities  and  Exchange  Commission  on March 22, 1996 and
          incorporated herein by reference



                                       37
<PAGE>


     (8)  Exhibit to the Company's  Registration  Statement on Form S-1 as filed
          with  the  Securities  and  Exchange   Commission   (Registration  No.
          33-42482)  effective  November  7,  1991 and  incorporated  herein  by
          reference

     (9)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1992 and
          incorporated herein by reference

     (10) Exhibit to the Company's  Form 10-KSB,  as amended,  as filed with the
          Securities and Exchange Commission for the fiscal year ending December
          31, 1993 and incorporated herein by reference

     (11) Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1994 and
          incorporated herein by reference

(b).  No reports on Form 8-K were  filed  during the last  quarter of the fiscal
year ended December 31, 1997.



                                       38
<PAGE>


                                   SIGNATURES

Pursuant to the  requirements of Section 13 or 15(d) of the Securities  Exchange
Act of 1934,  the  registrant has duly caused this Annual Report on Form 10-K to
be signed on its behalf by the undersigned, thereunto duly authorized.

                                          EMBREX, INC.

                                          By:  /s/ Randall L. Marcuson
                                               ---------------------------
Date: March 30, 1998                           Randall L. Marcuson
                                               President and Chief
                                               Executive Officer

Pursuant to the requirements of the Securities Exchange Act of 1934, this report
has been signed below by the following  persons on behalf of the  registrant and
in the capacities and on the dates indicated.

<TABLE>
<CAPTION>
Signature                                             Title                                                  Date
- ---------                                             -----                                                  ----

<S>                                            <C>                                                        <C>
/s/ Randall L. Marcuson                        President, Chief Executive Officer,                        March 30, 1998
- --------------------------------               and Director
Randall L. Marcuson

/s/ Don T. Seaquist
- --------------------------------               Vice President, Finance                                    March 30, 1998
Don T. Seaquist                                and Administration (Principal
                                               Financial and Accounting Officer)


*                                              Chairman of the                                            March 30, 1998
- --------------------------------               Board of Directors
Charles E. Austin

*                                              Director                                                   March 30, 1998
- --------------------------------
C. Daniel Blackshear

*                                              Director                                                   March 30, 1998
- --------------------------------
Lester M. Crawford, D.V.M. Ph.D.

*                                              Director                                                   March 30, 1998
- --------------------------------
Kenneth N. May, Ph.D.

*                                              Director                                                   March 30, 1998
- --------------------------------
Arthur M. Pappas
</TABLE>

*  By:    /s/ Randall L. Marcuson
          ---------------------------------------
          Randall L. Marcuson, as Attorney-in-Fact


                                       39
<PAGE>


                         Report of Independent Auditors

The Board of Directors
Embrex, Inc.

We have audited the  accompanying  statements  of net assets  available for plan
benefits of Embrex,  Inc.  Employee  Stock Purchase Plan as of December 31, 1997
and 1996, and the related  statement of changes in net assets available for plan
benefits  for each of the three years in the period  ended  December  31,  1997.
These financial  statements are the responsibility of the Company's  management.
Our responsibility is to express an opinion on these financial  statements based
on our audits.

We  conducted  our  audits  in  accordance  with  generally   accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements  referred to above present fairly, in
all material  respects,  the net assets  available  for plan benefits of Embrex,
Inc. Employee Stock Purchase Plan at December 31, 1997 and 1996, and the changes
in net assets  available  for plan  benefits  for each of the three years in the
period ended December 31, 1997 in conformity with generally accepted  accounting
principles.

                                           /s/ Ernst & Young LLP


Raleigh, North Carolina
March 19, 1998



                                       40
<PAGE>


              STATEMENTS OF NET ASSETS AVAILABLE FOR PLAN BENEFITS
                    EMBREX, INC. EMPLOYEE STOCK PURCHASE PLAN

                                                          At December 31,
                                                         1997         1996
                                                         ----         ----

Receivable from Company...........................     $ 38,666     $ 26,077
                                                       --------     --------

Net assets available for Plan benefits............     $ 38,666     $ 26,077
                                                       ========     ========

See accompanying notes.


                                       41
<PAGE>


         STATEMENTS OF CHANGES IN NET ASSETS AVAILABLE FOR PLAN BENEFITS
                    EMBREX, INC. EMPLOYEE STOCK PURCHASE PLAN

<TABLE>
<CAPTION>
                                                                    Years Ended December 31,
                                                                 1997            1996           1995
                                                              -------          -------        -------
<S>                                                           <C>              <C>            <C>
Employee contributions...................................     $  87,189        $79,487        $90,880

Deductions:

               Purchases of Common Stock.................        46,365         59,116         79,737

               Withdrawals...............................        28,245         31,394         15,862
                                                                -------        -------        -------
                                                                 74,600         90,510         95,601
                                                                -------        -------        -------

New (decrease) increase..................................        12,589        (11,023)        (4,721)

Net assets available for Plan benefits at
               beginning of period.......................        26,077         37,100         41,821
                                                                -------         -------        -------

Net assets available for Plan benefits at
               end of period.............................     $  38,666        $26,077        $37,100
                                                                =======        =======        =======

Shares of Common Stock purchased
               during year...............................         8,209         11,028         17,041
                                                                =======         =======        =======
</TABLE>


                                       42
<PAGE>


                    EMBREX, INC. EMPLOYEE STOCK PURCHASE PLAN
                          NOTES TO FINANCIAL STATEMENTS

                                December 31, 1997

NOTE 1 - BASIS OF PRESENTATION

The  accompanying  financial  statements  of the  Embrex,  Inc.  Employee  Stock
Purchase Plan ("the Plan") have been prepared on the accrual basis.

NOTE 2 - PLAN DESCRIPTION AND SUMMARY OF SIGNIFICANT PLAN PROVISIONS

The Board of  Directors  of Embrex,  Inc.  ("the  Company")  adopted the Plan on
January 28, 1993,  and the Plan was approved by  shareholders  of the Company at
the Annual Meeting of Shareholders on May 20, 1993. The Plan became effective as
of June 1, 1993.

The  purpose  of  this  Plan  is to  provide  the  Company's  employees  with an
additional  opportunity to share in the ownership of the Company. Under terms of
the Plan,  all regular  full-time  employees  of the Company may make  voluntary
payroll  contributions thereby enabling them to purchase Common Stock at a price
to be determined by the  Compensation  Committee of the Board, but not less than
85 percent of the lower of the fair market  values as of the beginning or end of
the twelve month offering period.

Contributions are limited to 20 percent of an employee's  compensation,  and the
aggregate  number of shares of Common  Stock which may be  purchased in total by
all Plan participants may not exceed 100,000 shares.

Contributions to the Plan are maintained in a non-interest bearing account until
such time as the  participant  exercises the option to purchase shares of Common
Stock from his or her available  contributions,  or withdraws  from the account.
All amounts  representing  net Plan assets are considered  general assets of the
Company and may be subject to the claims of creditors.

In addition to contributions,  plan activity consists of voluntary  purchases of
shares  of  Common  Stock  and  withdrawals  from  participation  in  the  Plan.
Participants  may purchase whole shares of Common Stock during a Purchase Period
(generally a twelve  month  period  ending each June 30th).  A  participant  may
withdraw from the Plan and cease making contributions at any time.

The Plan is not subject to the  provisions  of the  Employee  Retirement  Income
Security Act of 1974 ("ERISA") and is not qualified  under Section 401(a) of the
Internal  Revenue Code of 1986,  as amended which  relates to  qualification  of
certain pension, profit-sharing and stock bonus plans.

All costs to administer the Plan are paid by the Company.



                                       43
<PAGE>


Exhibits                    Description
- --------                    -----------

3.1(1)                      Restated Articles of Incorporation

3.2(2)                      Articles  of  Amendment  to  Restated   Articles  of
                            Incorporation, effective March 21, 1996

3.3(3)                      Articles  of  Amendment  to  Restated   Articles  of
                            Incorporation, effective May 28, 1996

3.4                         Amended and  Restated  Bylaws,  effective  March 27,
                            1998

4.1                         Reference is made to Exhibits 3.1, 3.2, 3.3 and 3.4

4.2(4)                      Specimen of Common Stock Certificate

4.3(5)                      Notices to holders of outstanding warrants regarding
                            adjustments   in  warrant   terms   resulting   from
                            Regulation S private placement

4.4(6)                      Form of Registration Rights Agreement

4.5(5)                      Form  of   Regulation  S   Securities   Subscription
                            Agreement

4.6(5)                      Form of Embrex 8%  Convertible  Debenture due May 1,
                            1997

4.7(5)                      Warrant to Purchase Common Stock of Embrex issued to
                            Schwartz Investments, Inc.

4.8(7)                      Rights  Agreement dated as of March 21, 1996 between
                            Embrex  and Branch  Banking  and Trust  Company,  as
                            Rights Agent

10.1(8)                     Exchange  Agreement  dated  May  28,  1991,  between
                            Embrex and American Cyanamid  Company,  Advent First
                            Limited  Partnership A,  Biotechnology  Venture Fund
                            S.A.,  Biotechnology   Investments  Limited,  Domain
                            Partners,  L.P.,  Elf  Technologies,   Inc.,  Prince
                            Venture    Partners   III,   L.P.,   3I   Securities
                            Corporation, and Charles E. Austin

10.2(8)                     Form of Stock Purchase  Warrant  exercisable for the
                            purchase of 180,003 shares of Common Stock

10.3(8)                     License  Agreement dated December 11, 1991,  between
                            Embrex  and  the  National   Technical   Information
                            Service,  a  primary  operating  unit of the  United
                            States Department of Commerce

10.4(8)                     Collaborative  Research  Agreement dated January 17,
                            1989 between Embrex and the University of Arkansas

10.5(8)                     License  Agreement  dated  October 1, 1988,  between
                            Embrex  and  the  National   Technical   Information
                            Service,  a  primary  operating  unit of the  United
                            States Department of Commerce

10.6(8)                     Lease  Agreement  dated  December  9,  1986  between
                            Embrex, as tenant,  and Imperial Center  Partnership
                            and Petula Associates, Ltd., as landlord, as amended
                            by  First  Amendment  dated  June 11,  1987,  Second
                            Amendment   dated   December  1,  1988,   and  Third
                            Amendment dated May 2, 1989

10.7(4)                     Fourth  Amendment  of Lease  dated  October  1, 1994
                            between the Company and Glaxo Inc. (as  successor in
                            interest to Imperial  Center  Partnership and Petula
                            Associates, Ltd.)

10.8(4)                     Fifth  Amendment  of Lease dated  December  13, 1996
                            between  the  Company and Glaxo  Wellcome  Inc.  (as
                            successor in interest to Glaxo Inc.)



                                       44
<PAGE>


Exhibits                    Description
- --------                    -----------

10.9                        Lease for Royal  Center II dated  October  13,  1997
                            between the Company and Petula Associates, Ltd.

10.10(8)                    Facility  Agreement  dated  March 1,  1991,  between
                            Embrex  and  Mississippi  Agriculture  and  Forestry
                            Experiment Station, Mississippi State University

10.11(8)                    Unrestricted  Grant  Agreement  dated April 1, 1988,
                            between Embrex and North Carolina State  University,
                            as amended by Amendment dated September 15, 1989 and
                            Amendment dated April 22, 1991

10.12(8)                    Unrestricted Grant Agreement dated November 1, 1986,
                            between Embrex and North Carolina State  University,
                            as amended by Amendment dated May 3, 1989, Amendment
                            dated  September 15, 1989, and Amendment dated April
                            22, 1991

10.13(8)                    Basic  Research  Agreement  dated  October 24, 1989,
                            between  Embrex  and  University  of  Arkansas,   as
                            amended on October  23,  1990,  February 1, 1991 and
                            July 22, 1991

10.14(8)                    1988  Incentive   Stock  Option  Plan  and  form  of
                            Incentive Stock Option Agreement

10.15(8)                    1989  Nonstatutory  Stock  Option  Plan  and form of
                            Nonstatutory Stock Option Agreement

10.16(8)                    1991  Nonstatutory  Stock  Option  Plan  and form of
                            Nonstatutory Stock Option Agreement

10.17(9)                    Incentive Stock Option and Nonstatutory Stock Option
                            Plan and  forms of Stock  Option  Agreements  - June
                            1993

10.18(3)                    Amendment  dated  May 16,  1996 to  Incentive  Stock
                            Option and  Nonstatutory  Stock  Option  Plan - June
                            1993

10.19(4)                    Amended and Restated Employee Stock Purchase Plan

10.20(8)                    Employment   Agreement   dated  November  15,  1989,
                            between Embrex and Randall L. Marcuson

10.21(4)                    Amendment to Employment Agreement dated May 21, 1996
                            between Embrex and Randall L. Marcuson

10.22(4)                    Change In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Randall L. Marcuson

10.23(8)                    Employment Agreement dated October 16, 1989, between
                            Embrex and Catherine A. Ricks

10.24(4)                    Change In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Catherine A. Ricks

10.25(2)                    General  Provisions to Employment  Agreement between
                            Embrex and Brian V. Cosgriff dated August 18, 1995

10.26(4)                    Charge In Control Severance  Agreement dated May 21,
                            1996 between Embrex and Brian V. Cosgriff

10.27(2)                    Terms and  Conditions of Employment  between  Embrex
                            Europe  Limited  and David M.  Baines  dated May 12,
                            1994


                                       45
<PAGE>


Exhibits                    Description
- --------                    -----------

10.28(4)                    Change In Control Severance  Agreement dated June 9,
                            1996 between Embrex and David M. Baines

10.29(4)                    Letter   Agreement   and   General   Provisions   to
                            Employment  Agreement  dated August 20, 1996 between
                            Embrex  and  Don  T.   Seaquist  and   Amendment  to
                            Employment Agreement dated September 9, 1996 between
                            Embrex and Don T. Seaquist

10.30(4)                    Change  In   Control   Severance   Agreement   dated
                            September 9, 1996 between Embrex and Don T. Seaquist

10.31(4)                    Letter   Agreement   and   General   Provisions   to
                            Employment  Agreement  dated August 26, 1996 between
                            Embrex and Rick L. Ryan and  Amendment to Employment
                            Agreement  dated August 26, 1996 between  Embrex and
                            Rick L. Ryan

10.32(4)                    Change In Control  Severance  Agreement dated August
                            26, 1996 between Embrex and Rick L. Ryan

10.33(8)                    Shareholders' Agreement dated August 14, 1991 by and
                            among   Embrex,    Advent    Euroventures    Limited
                            Partnership,  and  Plant  Resource  Venture  Fund II
                            Limited Partnership

10.34                       INOVOJECT(R) Egg  Injection  System  Lease,  Limited
                            License,   Supply  and   Service   Agreement   dated
                            September  1, 1994  between  Embrex and Tyson Foods,
                            Inc.  (asterisks  located  within the exhibit denote
                            information  which has been  deleted  pursuant  to a
                            request for  confidential  treatment  filed with the
                            Securities and Exchange Commission)

10.35                       Amendment  dated March 26, 1997 to the  INOVOJECT(R)
                            Egg Injection System Lease, Limited License,  Supply
                            and  Service   Agreement  dated  September  1,  1994
                            between  Embrex  and Tyson  Foods,  Inc.  (asterisks
                            located within the exhibit denote  information which
                            has  been   deleted   pursuant   to  a  request  for
                            confidential treatment filed with the Securities and
                            Exchange Commission)

10.36(10)                   Master  Lease   Agreement  dated  December  3,  1993
                            between Embrex and Capital Associates International,
                            Inc.   with  a  form  of   equipment   schedule  and
                            collateral assignment of lease attached

10.37(10)                   Master  Lease   Agreement  dated  January  28,  1994
                            between  Embrex  and  Aberlyn   Capital   Management
                            Limited  Partnership  with a form of lease  schedule
                            and collateral assignment of lease attached

10.38(10)                   Agreement to Issue  Warrant  dated  January 28, 1994
                            between  Embrex  and  Aberlyn   Capital   Management
                            Limited Partnership

10.39(10)                   Common  Stock  Purchase  Warrant  issued to  Aberlyn
                            Capital Management Limited Partnership

10.40(10)                   Agreement to Issue  Warrant  dated  January 28, 1994
                            between Embrex and Aberlyn Holding Company, Inc.

10.41(10)                   Common  Stock  Purchase  Warrant  issued to  Aberlyn
                            Holding Company, Inc.

10.42(11)                   Master   Equipment   Lease  Agreement  dated  as  of
                            December  7,  1994  between  Financing  for  Science
                            International,  Inc.  and  Embrex  with a Consent to
                            Assignment of Equipment  Lease  Agreement,  Security
                            Agreement and Rental Schedule attached


                                       46
<PAGE>


Exhibits                    Description
- --------                    -----------

10.43(11)                   License  Agreement  dated  as of  December  7,  1994
                            between  Financing for Science  International,  Inc.
                            and Embrex with Sublicense Agreement attached

10.44(11)                   Common Stock Purchase Warrant dated January 17, 1995
                            issued to Financing for Science International, Inc.

10.45(11)                   Agreement  for Sale of  Equipment  and Rights  Under
                            User Agreement  dated as of December 7, 1994 between
                            Financing for Science International, Inc. and Embrex

10.46(5)                    Letter of  Agreement  for $6.0  million  Convertible
                            Regulation  S Private  Placement  by and between the
                            Company and Swartz  Investments,  Inc., as placement
                            agent

10.47(2)                    Limited  License  and Supply  Agreement  dated as of
                            July 20, 1995 between Embrex and Webster

10.48(4)                    Amendments  dated  August 1, 1996 and  November  11,
                            1996 to Limited  License and Supply  Agreement dated
                            as of July 20, 1995 between Embrex and Webster

10.49(2)                    Agreement  dated  as of  January  22,  1996  between
                            Embrex and Select

10.50(2)                    Letter  Agreement  dated  as  of  January  22,  1996
                            between Select and Embrex

10.51(2)                    License  dated as of  January  22,  1996  granted by
                            Select to Embrex

10.52(2)                    Commitment  letter  accepted  June 14, 1995  between
                            Embrex and Financing for Science International, Inc.
                            for $2.0 million capital lease financing facility

10.53(2)                    Stock Purchase  Warrant dated June 9, 1995 issued to
                            Financing for Science International, Inc.

10.54(2)                    Financing  Agreement  (Number  10783)  dated  as  of
                            October 30, 1995 between Lease Management  Services,
                            Inc. and Embrex,  and Addendum thereto dated October
                            30, 1995 attached

10.55(2)                    License  Agreement  dated  October 30, 1995  between
                            Embrex and Lease Management Services, Inc.

10.56(2)                    Sublicense  Agreement  dated as of October  30, 1995
                            between Embrex and Lease Management Services, Inc.

10.57(2)                    Movable Hypothec on Equipment and Contracts dated as
                            of  October  30,  1995  between   Embrex  and  Lease
                            Management Services, Inc.

10.58(2)                    Warrant to Purchase  30,000  Shares of Common  Stock
                            dated  October 30,  1995 issued to Lease  Management
                            Services, Inc.

10.59(2)                    Intercreditor Agreement dated as of October 31, 1995
                            among  Financing  for Science  International,  Inc.,
                            Lease Management Services, Inc., and Embrex.

10.60(4)                    Embrex Europe Limited Loan Agreement  dated April 3,
                            1996

21                          Subsidiaries


                                       47
<PAGE>


Exhibits                    Description
- --------                    -----------

23                          Consent  of Ernst & Young  LLP to the  inclusion  of
                            their report dated February 20, 1998 with respect to
                            the consolidated financial statements of the Company
                            in this Form 10-K and the incorporation by reference
                            of such report into the  Registration  Statement  on
                            Form  S-3  (No.   333-18231),   as  filed  with  the
                            Securities  and Exchange  Commission on December 19,
                            1996, and into the Registration Statements under the
                            Securities  Act of 1933 on  Form  S-8  (Registration
                            Nos.  33-51582,  33-63318 and  333-04109),  as filed
                            with  the  Securities  and  Exchange  Commission  on
                            September 1, 1992,  May 25, 1993,  and May 20, 1996,
                            respectively,  and to the incorporation by reference
                            in  the   Registration   Statement   on   Form   S-8
                            (Registration   No.  33-63318)   pertaining  to  the
                            Employee  Stock  Purchase Plan of their report dated
                            March  19,  1998  with  respect  to  the   financial
                            statements  of  the  Embrex,   Inc.  Employee  Stock
                            Purchase Plan included in this Form 10-K.

24                          Powers of Attorney

27.1                        Financial Data Schedule to the Company's Form 10-K
                            for the year ended December 31, 1997.

27.2                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended September 30, 1997
                            as filed with the  Securities and Exchange
                            Commission on November 10, 1997 due to the change in
                            the earnings per share calculation as a result of
                            the adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on December
                            31, 1997.


27.3                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended June 30, 1997 as
                            filed with the Securities and Exchange Commission
                            on August 12, 1997, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on
                            December 31, 1997.

27.4                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended March 31, 1997 as
                            filed with the Securities and Exchange Commission
                            on May 7, 1997, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on
                            December 31, 1997, and to reflect a restatement of
                            the Company's _____________ for such quarter.

27.5                        Restated Financial Data Schedule to the Company's
                            Form 10-K for the year ended December 31, 1996 as
                            filed with the Securities and Exchange Commission
                            on March 31, 1997, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on
                            December 31, 1997.

27.6                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended September 30, 1996
                            as filed with the Securities and Exchange Commission
                            on November 30, 1996, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on December
                            31, 1997.

27.7                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended June 30, 1996
                            as filed with the Securities and Exchange Commission
                            on August 12, 1996, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on December
                            31, 1997.

27.8                        Restated Financial Data Schedule to the Company's
                            Form 10-Q for the quarter ended March 31, 1996
                            as filed with the Securities and Exchange Commission
                            on May 13, 1996, due to the change in the
                            earnings per share calculation as a result of the
                            adoption of Statement of Financial Accounting
                            Standards No. 128, "Earnings Per Share" on December
                            31, 1997.

99                          Risk Factors relating to the Company

- ----------
     (1)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission  for fiscal  year  ending  December  31, 1991 and
          incorporated herein by reference

     (2)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1995 and
          incorporated herein by reference

     (3)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  June 30,  1996 and
          incorporated herein by reference

     (4)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission  for fiscal  year  ending  December  31, 1996 and
          incorporated herein by reference

     (5)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  June 30,  1995 and
          incorporated herein by reference

     (6)  Exhibit to the Company's  Form 10-Q as filed with the  Securities  and
          Exchange  Commission  for the three  months  ended  March 31, 1995 and
          incorporated herein by reference

     (7)  Exhibit to the Company's  Registration  Statement on Form 8-A as filed
          with the  Securities  and  Exchange  Commission  on March 22, 1996 and
          incorporated herein by reference

     (8)  Exhibit to the Company's  Registration  Statement on Form S-1 as filed
          with  the  Securities  and  Exchange   Commission   (Registration  No.
          33-42482)  effective  November  7,  1991 and  incorporated  herein  by
          reference

     (9)  Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1992 and
          incorporated herein by reference



                                       48
<PAGE>


     (10) Exhibit to the Company's  Form 10-KSB,  as amended,  as filed with the
          Securities and Exchange Commission for the fiscal year ending December
          31, 1993 and incorporated herein by reference

     (11) Exhibit to the Company's  Form 10-K as filed with the  Securities  and
          Exchange  Commission for the fiscal year ending  December 31, 1994 and
          incorporated herein by reference



                                       49


                  AMENDED AND RESTATED EFFECTIVE MARCH 27, 1998


                           AMENDED AND RESTATED BYLAWS
                                       OF
                                  EMBREX, INC.


                                    ARTICLE I
                                    ---------

                                   DEFINITIONS
                                   -----------

         In these bylaws, unless otherwise provided, the following terms shall
have the following meanings:

                  (1) "Act" shall mean the North Carolina Business Corporation
Act as codified in Chapter 55 of the North Carolina General Statutes effective
July 1, 1990, and as amended from time to time;

                  (2) "Articles of Incorporation" shall mean the Corporation's
articles of incorporation, including amended and restated articles of
incorporation and articles of merger;

                  (3) "Corporation" shall mean Embrex, Inc.;

                  (4) "Distribution" shall mean a direct or indirect transfer of
money or other property (except the Corporation's own shares) or incurrence of
indebtedness by the Corporation to or for the benefit of its shareholders in
respect of any of its shares. A distribution may be in the form of a declaration
or payment of a dividend, a purchase, redemption, or other acquisition of
shares, a distribution of indebtedness, or otherwise;

                  (5) "Emergency" shall mean a catastrophic event which prevents
a quorum of the board of directors from being readily assembled;

                  (6) "Shares" shall mean the units into which the proprietary
interests in the Corporation are divided; and

                  (7) "Voting group" shall mean all shares of one or more
classes or series that under the articles of incorporation or the Act are
entitled to vote and be counted together collectively on a matter at a meeting
of shareholders. All shares entitled by the articles of incorporation or the Act
to vote generally on a matter are for that purpose a single voting group.


                                   ARTICLE II

                                     OFFICES

         SECTION 1. PRINCIPAL OFFICE: The principal office of the Corporation
shall be located at 1035 Swabia Court, Durham, Durham County, North Carolina
27703, or at such other place as may be determined from time to time by the
directors.

         SECTION 2. REGISTERED OFFICE: The registered office of the Corporation
shall be located at 1035 Swabia Court, Durham, Durham County, North Carolina
27703.

         SECTION 3. OTHER OFFICES: The Corporation may have offices at such
other places, either within or without the State of North Carolina, as the board
of directors may from time to time determine, or as the affairs of the
Corporation may require.


                                   ARTICLE III
                                   -----------

                            MEETINGS OF SHAREHOLDERS
                            ------------------------

         SECTION 1. PLACE OF MEETINGS: All meetings of shareholders shall be
held at the principal office of the Corporation, or at such other place, either
within or without the State of North Carolina, as shall be designated in the
notice of the meeting or as may be agreed upon by a majority of the shareholders
entitled to vote at the meeting.

         SECTION 2. ANNUAL MEETING: The annual meeting of shareholders for the
election of directors and the transaction of other business shall be held
annually in any month on any day (except Saturday, Sunday or a legal holiday) as
fixed by the board of directors.

         SECTION 3. SUBSTITUTE ANNUAL MEETING: If the annual meeting shall not
be held on the day designated by these bylaws, a substitute annual meeting may
be called by the board of directors, the chairman of the board, the chief
executive officer or the president. A meeting so called shall be designated and
treated for all purposes as the annual meeting.

         SECTION 4. SPECIAL MEETINGS: Special meetings of the shareholders may
be called at any time by the board of directors, the chairman of the board, the
chief executive officer or the president. Only business within the purpose or
purposes described in the meeting notice specified in Section 6 of this Article
may be conducted at a special meeting of shareholders.

         SECTION 5. CONDUCT OF BUSINESS: The chairman of the meeting of
shareholders shall determine the order of business and the procedure at the
meeting, including such regulation of the manner of voting and the conduct of
discussion as seem to him in order.

         SECTION 6. NOTICE OF MEETING: Written or printed notice stating the
time and place of the meeting shall be delivered not less than ten (10) nor more
than sixty (60) days before the date of any shareholders' meeting, either
personally, by mail, by telegraph, by teletype, or by facsimile transmission, by
or at the direction of the chairman of the board, the chief executive officer,
the president, the secretary, or other person calling the meeting to each
shareholder of record entitled to vote at such meeting. If mailed, such notice
shall be deemed to be delivered when deposited in the United States mail,
addressed to the shareholder at his address as it appears on the record of the
shareholders of the Corporation, with postage thereon prepaid.

         In the case of a special meeting, the notice of meeting shall
specifically state the purpose or purposes for which the meeting is called. In
the case of an annual or substitute annual meeting, the notice of meeting need
not specifically state the business to be transacted unless such a statement is
required by the Act.

         When an annual or special meeting is adjourned to a different date,
time, and place, it is not necessary to give any notice of the adjourned meeting
other than by announcement at the meeting at which the adjournment is taken;
provided, however, that if a new record date for the adjourned meeting is or
must be set, notice of the adjourned meeting must be given to persons who are
shareholders as of the new record date.

                                       2
<PAGE>


         The record date for determining the shareholders entitled to notice of
and to vote at an annual or special meeting shall be fixed as provided in
Section 3 of Article VIII.

         SECTION 7. WAIVER OF NOTICE: A shareholder may waive notice of any
meeting either before or after such meeting. Such waiver shall be in writing,
signed by the shareholder, and filed with the minutes or corporate records. A
shareholder's attendance at a meeting: (i) waives objection to lack of notice or
defective notice of the meeting, unless the shareholder at the beginning of the
meeting objects to holding the meeting or transacting business at the meeting;
and (ii) waives objection to consideration of a particular matter at the meeting
that is not within the purpose or purposes described in the meeting notice,
unless the shareholder objects to considering the matter before it is voted
upon.

         SECTION 8. SHAREHOLDER LIST: Commencing two (2) business days after
notice of a meeting of shareholders is given and continuing through such
meeting, the secretary of the Corporation shall maintain at the principal office
of the Corporation an alphabetical list of the shareholders entitled to vote at
such meeting, arranged by voting group, with the address of and number of shares
held by each. This list shall be subject to inspection by any shareholder or his
agent or attorney at any time during usual business hours and may be copied at
the shareholder's expense.

         SECTION 9. QUORUM: A majority of the votes entitled to be cast on a
matter by any voting group, represented in person or by proxy, shall constitute
a quorum of that voting group for action on that matter. The shareholders
present at a duly organized meeting may continue to transact business until
adjournment, notwithstanding the withdrawal of enough shareholders to leave less
than a quorum.

         In the absence of a quorum at the opening of any meeting of
shareholders, such meeting may be adjourned from time to time by a majority of
the votes voting on the motion to adjourn; and at any adjourned meeting at which
a quorum is present, any business may be transacted which might have been
transacted at the original meeting.

         SECTION 10. PROXIES: Shares may be voted either in person or by one or
more agents authorized by a written proxy executed by the shareholder or by his
duly authorized attorney in fact. A proxy may take the form of a telegram,
telex, facsimile or other form of wire or wireless communication which appears
to have been transmitted by a shareholder. A proxy is effective when received by
the secretary or other officer or agent authorized to tabulate votes. A proxy is
not valid after the expiration of eleven (11) months from the date of its
execution, unless the person executing it specifies therein the length of time
for which it is to continue in force or limits its use to a particular meeting.

         SECTION 11. VOTING OF SHARES: Unless otherwise provided in these
bylaws, the articles of incorporation, or the Act, each outstanding share,
regardless of class, shall be entitled to one vote on each matter submitted to a
vote at a meeting of shareholders.

         Except for the election of directors, which is governed by the
provisions of Section 4 of Article IV, if a quorum is present, action on a
matter by a voting group is approved if the votes cast within the voting group
favoring the action exceed the votes cast against the action, unless the vote of
a greater number is required by the Act, the articles of incorporation, or these
bylaws.

         Shares of the Corporation are not entitled to vote if: (i) they are
owned, directly or indirectly, by the Corporation, unless they are held by it in
a fiduciary capacity; (ii) they are owned, directly or 

                                       3
<PAGE>

indirectly, by a second corporation in which the Corporation owns a majority of
the shares entitled to vote for directors of the second corporation; or (iii)
they are redeemable shares and (x) notice of redemption has been given and (y) a
sum sufficient to redeem the shares has been deposited with a bank, trust
company, or other financial institution under an irrevocable obligation to pay
the holders the redemption price upon surrender of the shares.

         Either the board of directors or the chairman of the meeting may
appoint one or more voting inspectors, each of whom shall take an oath to
execute his duties impartially and to the best of his ability. The voting
inspector may be an officer, employee or agent of the Corporation. The voting
inspectors shall, by majority vote, resolve all questions regarding voting of
shares, including the number of shares outstanding, the voting power of each,
the shares represented at the meeting, the qualification of voters, the validity
of proxies, the existence of a quorum as to any voting group, and the
acceptance, rejection and tabulation of votes.

         SECTION 12. INFORMAL ACTION BY SHAREHOLDERS: Any action which may be
taken at a meeting of the shareholders may be taken without a meeting if a
consent in writing, setting forth the action so taken, is signed by all of the
persons who would be entitled to vote upon such action at a meeting and is
delivered to the Corporation to be included in the minutes or to be kept as part
of the corporate records.

         SECTION 13. SHAREHOLDER PROPOSALS: Any shareholder wishing to bring any
business before a meeting of shareholders must provide notice to the Corporation
not more than ninety (90) and not less than fifty (50) days before the meeting
in writing by registered mail, return receipt requested, of the business to be
presented by such shareholder at the meeting. Any such notice shall set forth
the following as to each matter the shareholder proposes to bring before the
meeting: (i) a brief description of the business desired to be brought before
the meeting and the reasons for conducting such business at the meeting and, if
such business includes a proposal to amend the bylaws of the Corporation, the
language of the proposed amendment; (ii) the name and address, as they appear on
the Corporation's books, of the shareholder proposing such business; (iii) the
class and number of shares of the Corporation which are beneficially owned by
such shareholder; (iv) a representation that the shareholder is a holder of
record of stock of the Corporation entitled to vote at such meeting and intends
to appear in person or by proxy at the meeting to propose such business; and (v)
any material interest of the shareholder in such business. Notwithstanding the
foregoing provisions of this Section, a shareholder shall also comply with all
applicable requirements of the Securities Exchange Act of 1934, as amended, and
the rules and regulations thereunder with respect to the matters set forth in
this Section. In the absence of such notice to the Corporation meeting the above
requirements, a shareholder shall not be entitled to present any business at any
meeting of the shareholders.

         SECTION 14. CORPORATION'S ACCEPTANCE OF VOTES: If the name signed on a
vote, consent, waiver, or proxy appointment corresponds to the name of a
shareholder, the Corporation is entitled to accept the vote, consent, waiver, or
proxy appointment and to give it effect as the act of the shareholder.

         If the name signed on a vote, consent, waiver, or proxy appointment
does not correspond to the name of its shareholder, the Corporation is
nevertheless entitled to accept the vote, consent, waiver, or proxy appointment
and to give it effect as the act of the shareholder if: (i) the shareholder is
an entity and the name signed purports to be that of an officer or agent of the
entity; (ii) the name signed purports to be that of an administrator, executor,
guardian, or conservator representing the shareholder and, if the Corporation
requests, evidence of fiduciary status acceptable to the Corporation has been
presented with respect to the vote, consent, waiver, or proxy appointment; (iii)
the name signed purports to be that of a receiver or trustee in bankruptcy of
the shareholder and, if 


                                       4
<PAGE>


the Corporation requests, evidence of its status acceptable to the Corporation
has been presented with respect to the vote, consent, waiver, or proxy
appointment; (iv) the name signed purports to be that of a beneficial owner or
attorney-in-fact of the shareholder and, if the Corporation requests, evidence
acceptable to the Corporation of the signatory's authority to sign for the
shareholder has been presented with respect to the vote, consent, waiver, or
proxy appointment; or (v) two or more persons are the shareholder as co-tenants
or fiduciaries and the name signed purports to be the name of at least one of
the co-owners and the person signing appears to be acting on behalf of all the
co-owners.

         The Corporation is entitled to reject a vote, consent, waiver, or proxy
appointment if the secretary or other officer or agent authorized to tabulate
votes has a reasonable basis for doubt about the validity of the signature on it
or about the signatory's authority to sign for the shareholder.

         SECTION 15. NUMBER OF SHAREHOLDERS: The following persons or entities
identified as a shareholder in the Corporation's current record of shareholders
constitute one shareholder for purposes of these bylaws: (i) all co-owners of
the same shares; (ii) a corporation, partnership, trust, estate, or other
entity; (iii) the trustees, guardians, custodians, or other fiduciaries of a
single trust, estate, or account. Shareholdings registered in substantially
similar names constitute one shareholder if it is reasonable to believe that the
names represent the same person.


                                   ARTICLE IV
                                   ----------

                               BOARD OF DIRECTORS
                               ------------------

         SECTION 1. GENERAL POWERS: All corporate powers shall be exercised by
or under the authority of, and the business and affairs of the Corporation shall
be managed under the direction of, its board of directors.

         SECTION 2. NUMBER, TERM AND QUALIFICATIONS: The number constituting the
board of directors shall be not less than one (1) nor more than seven (7). The
number of directors within this variable range may be fixed or changed from time
to time by the shareholders or the board of directors. Each director shall hold
office until his death, resignation, retirement, removal, disqualification, or
until his successor is elected and qualified. Directors need not be residents of
the State of North Carolina or shareholders of the Corporation.

         SECTION 3. NOMINATION OF DIRECTORS: Nominations for the election of
directors may only be made by the board of directors, by the nominating
committee of the board of directors (or, if none, any other committee serving a
similar function) or by any shareholder entitled to vote generally in elections
of directors where the shareholder complies with the requirements of this
Section. The Chief Executive Officer of the Corporation shall be a nominee for
election to the board of directors. Any shareholder of record entitled to vote
generally in elections of directors may nominate one or more persons for
election as directors at a meeting of shareholders only if written notice of
such shareholder's intent to make such nomination or nominations has been given,
either by personal delivery or by registered mail, return receipt requested, to
the Secretary of the Corporation (i) with respect to an election to be held at
an annual meeting of shareholders, not more than ninety (90) days nor less than
fifty (50) days in advance of such meeting; and (ii) with respect to an election
to be held at a special meeting of shareholders called for the purpose of the
election of directors, not later than the close of business on the tenth
business day following the date on which notice of such meeting is first given
to shareholders. Each such notice of a shareholder's intent to nominate a
director or directors at an annual or special meeting shall set forth the
following: (A) the name and address, as they appear on the Corporation's books,
of the shareholder who intends to make the

                                       5

<PAGE>


 nomination and the name and residence address of the person or persons to be
nominated; (B) the class and number of shares of the Corporation which are
beneficially owned by the shareholder; (C) a representation that the shareholder
is a holder of record of stock of the Corporation entitled to vote at such
meeting and intends to appear in person or by proxy at the meeting to nominate
the person or persons specified in the notice; (D) a description of all
arrangements or understandings between the shareholder and each nominee and any
other person or persons (naming such person or persons) pursuant to which the
nomination or nominations are to be made by the shareholders; (E) such other
information regarding each nominee proposed by such shareholder as would be
required to be disclosed in solicitations of proxies for election of directors,
or as would otherwise be required, in each case pursuant to Regulation 14A under
the Securities and Exchange Act of 1934, as amended, including any information
that would be required to be included in a proxy statement filed pursuant to
Regulation 14A had the nominee been nominated by the board of directors; and (F)
the written consent of each nominee to be named in a proxy statement and to
serve as director of the Corporation if so elected. No person nominated by a
shareholder shall be eligible to serve as a director of the Corporation unless
nominated in accordance with the procedures set forth in this Section. If the
chairman of the shareholders meeting shall determine that a nomination was not
made in accordance with the procedures described by the bylaws of the
Corporation, he shall so declare to the meeting, and the defective nomination
shall be disregarded. Notwithstanding the foregoing provisions of this Section,
a shareholder shall also comply with all applicable requirements of the
Securities Exchange Act of 1934, as amended, and the rules and regulations
thereunder with respect to the matters set forth in this Section.

         SECTION 4. ELECTION OF DIRECTORS: Except as provided in Section 6 of
this Article, the directors shall be elected at the annual meeting of
shareholders by plurality vote; and accordingly those persons who receive the
highest number of votes shall be deemed to have been elected. If any shareholder
so demands, the election of directors shall be by ballot.

         SECTION 5. REMOVAL: Any director, or the entire board of directors, may
be removed from office at any time, with or without cause, but only if the
number of votes cast to remove him exceeds the number of votes cast not to
remove him. If a director is elected by a voting group of shareholders, only
members of that voting group may participate in the vote to remove him. A
director may not be removed by the shareholders at a meeting unless the notice
of the meeting specifies such removal as one of its purposes. If any directors
are removed, new directors may be elected at the same meeting.

         SECTION 6. VACANCIES: Any vacancy occurring in the board of directors,
including, without limitation, a vacancy resulting from an increase in the
number of directors or from the failure by the shareholders to elect the full
authorized number of directors, shall be filled by the shareholders or the board
of directors. If such vacancy is to be filled by the board of directors, and if
the directors remaining in office constitute fewer than a quorum of the board,
such vacancy may be filled by the affirmative vote of a majority of the
remaining directors or by the sole remaining director. If the vacant office was
held by a director elected by a voting group of shareholders, only the remaining
director or directors elected by that voting group or the holders of shares of
that voting group are entitled to fill the vacancy. The term of a director
elected to fill a vacancy shall expire at the next shareholders' meeting at
which directors are elected.

         SECTION 7. CHAIRMAN OF THE BOARD: The board of directors from time to
time may appoint from their number a chairman of the board. The chairman of the
board, if one is appointed, shall preside at all meetings of the board of
directors and the shareholders and shall perform such other duties as may be
prescribed from time to time by the board of directors.

                                       6
<PAGE>

         SECTION 8. COMPENSATION: The board of directors may compensate
directors for their services as such and may provide for the payment of all
expenses incurred by directors in attending regular and special meetings of the
board.

         SECTION 9. COMMITTEES: The board of directors may create one or more
committees of the board, each of which shall have at least two (2) members, all
of whom shall be directors. The creation of a committee and the appointment of
members to it must be approved by a majority of all the directors in office when
the action is taken. Each committee may, as specified by the board of directors,
exercise some or all of the authority of the board except that a committee may
not: (i) authorize distributions; (ii) approve or propose to shareholders action
that the Act requires be approved by shareholders; (iii) fill vacancies on the
board of directors or on any of its committees; (iv) amend the articles of
incorporation pursuant to N.C. Gen. Stat. Section 55-10-02 or its successor; (v)
adopt, amend, or repeal bylaws; (vi) approve a plan of merger not requiring
shareholder approval; (vii) authorize or approve a reacquisition of shares,
except according to a formula or method prescribed by the board of directors; or
(viii) authorize or approve the issuance or sale or contract for sale of shares,
or determine the designation and relative rights, preferences, and limitations
of a class or series of shares, except that the board of directors may authorize
a committee to do so within limits specifically prescribed by the board of
directors to the full extent permitted by applicable law. The provisions of
Article V, which govern meetings of the board of directors, shall likewise apply
to meetings of any committee of the board.

         SECTION 10. EXECUTIVE COMMITTEE: In accordance with Section 9 of this
Article, the board of directors may designate an executive committee. Subject to
the provisions of Section 9 of this Article, any executive committee so
designated may exercise all of the power of the board of directors during
intervals between meetings thereof, including but not limited to the power to
authorize the execution of contracts, deeds, leases, and other agreements
respecting real or personal property. The board of directors shall approve,
disapprove, or modify action taken by any such executive committee and shall
record such action in the minutes of the board meeting.


                                    ARTICLE V

                              MEETINGS OF DIRECTORS

         SECTION 1. REGULAR MEETINGS: Regular meetings of the board of directors
shall be held at such place or places, on such date or dates, and at such time
or times as shall have been established by the board of directors and publicized
among all directors.

         SECTION 2. SPECIAL MEETINGS: Special meetings of the board of directors
may be called by one-third of the directors then in office or by the chief
executive officer and shall be held at such place, either within or without the
State of North Carolina, on such date, and at such time as they or he shall fix.

         SECTION 3. NOTICE OF MEETINGS: Regular meetings of the board of
directors may be held without notice. The person or persons calling a special
meeting of the board of directors shall, at least three (3) days before the
meeting, give notice of the meeting by any usual means of communication,
including by telephone, telegraph, teletype, mail, private carrier, facsimile
transmission, or other form of wire or wireless communication. Such notice may
be oral and need not specify the purpose for which the meeting is called.

         SECTION 4. WAIVER OF NOTICE: Any director may waive notice of any
meeting either before or after such meeting. Such waiver shall be in writing,
signed by the director, and filed with the 

                                       7
<PAGE>

minutes or corporate records; provided, however, that a director's attendance at
or participation in a meeting waives any required notice to him unless the
director at the beginning of the meeting (or promptly upon his arrival) objects
to holding the meeting or transacting business at the meeting and does not
thereafter vote for or assent to action taken at the meeting.

         SECTION 5. QUORUM: A majority of the directors fixed by or pursuant to
these bylaws shall constitute a quorum for the transaction of business at any
meeting of the board of directors.

         SECTION 6. MANNER OF ACTING: The act of a majority of the directors
present at a meeting at which a quorum is present shall be the act of the board
of directors, unless a greater number is required by the articles of
incorporation or these bylaws.

         SECTION 7. PRESUMPTION OF ASSENT: A director of the Corporation who is
present at a meeting of the board of directors or a committee of the board of
directors when corporate action is taken is deemed to have assented to the
action taken unless: (i) he objects at the beginning of the meeting (or promptly
upon his arrival) to holding it or transacting business at the meeting; (ii) his
dissent or abstention from the action taken is entered in the minutes of the
meeting; or (iii) he files written notice of his dissent or abstention with the
presiding officer of the meeting before its adjournment or with the Corporation
immediately after adjournment of the meeting. This right of dissent or
abstention is not available to a director who votes in favor of the action
taken.

         SECTION 8. PARTICIPATION IN MEETINGS: Any or all of the directors may
participate in a regular or special meeting by, or conduct the meeting through
the use of, any means of communication by which all directors participating may
simultaneously hear each other during the meeting.

         SECTION 9. ACTION WITHOUT MEETING: Action which may be taken at a board
of directors meeting may be taken without a meeting if the action is taken by
all members of the board and is evidenced by one or more written consents signed
by each director before or after such action, which describes the action taken
and is included in the minutes or filed with the corporate records. Such action
is effective when the last director signs the consent, unless the consent
specifies a different effective date.


                                   ARTICLE VI

                                    OFFICERS

         SECTION 1. OFFICERS OF THE CORPORATION: The officers of the Corporation
shall consist of a chief executive officer, president, secretary, treasurer, and
such vice presidents, assistant secretaries, assistant treasurers, and other
officers as the board of directors may from time to time appoint. Any two or
more offices may be held by the same person, but no officer may act in more than
one capacity where action of two or more officers is required.

         SECTION 2. APPOINTMENT AND TERM: The officers of the Corporation shall
be appointed by the board of directors. A duly appointed officer may appoint one
or more officers or assistant officers if authorized by the board of directors.
Each officer shall hold office until his death, resignation, retirement,
removal, disqualification or until his successor is appointed and qualifies. The
appointment of an officer does not itself create contract rights for either the
officer or the Corporation.

                                       8

<PAGE>

         SECTION 3. COMPENSATION OF OFFICERS: The compensation of officers of
the Corporation shall be fixed by the board of directors. No officer shall
receive compensation for serving the Corporation in any other capacity unless
such additional compensation be authorized by the board of directors.

         SECTION 4. RESIGNATION AND REMOVAL: An officer may resign at any time
by communicating his resignation to the Corporation. A resignation is effective
when it is communicated unless it specifies in writing a later date. If a
resignation is made effective as of a later date and the Corporation accepts the
future effective date, the board of directors may fill the pending vacancy
before the effective date if the board provides that the successor does not take
office until the effective date. An officer's resignation does not affect the
Corporation's contract rights, if any, with the officer. Any officer or agent
appointed by the board of directors may be removed by the board at any time,
with or without cause, but such removal shall be without prejudice to the
contract rights, if any, of the person so removed.

         SECTION 5. BONDS: The board of directors may by resolution require any
officer, agent, or employee of the Corporation to give bond to the Corporation,
with sufficient sureties, conditioned on the faithful performance of the duties
of his respective office or position, and to comply with such other conditions
as may from time to time be required by the board of directors.

         SECTION 6. CHIEF EXECUTIVE OFFICER: The chief executive officer shall
have general authority and supervision over the officers and employees of the
Corporation, and shall perform such other duties as may be prescribed from time
to time by the board of directors. All officers shall report to him except to
the extent specifically required by the board of directors. He shall consult
with the president as to matters within the scope of the authority of the
president. He shall have the authority to sign certificates for shares, as well
as any deeds, mortgages, contracts, or other instruments which the board of
directors has authorized to be executed, except in cases where the signing and
execution of such contracts or instruments shall be expressly delegated by the
board of directors or by these bylaws to some other officer or agent of the
Corporation, or shall be required by the Act to be otherwise signed or executed.

         SECTION 7. PRESIDENT: The president shall be the chief operating
officer of the Corporation and shall have general charge of the operation of the
business of the Corporation. The president shall perform such duties and have
such powers as the board of directors from time to time may assign. He shall
have the authority to sign certificates for shares, as well as any deeds,
mortgages, contracts, or other instruments which the board of directors has
authorized to be executed, except in cases where the signing and execution of
such contracts or instruments shall be expressly delegated by the board of
directors or by these bylaws to some other officer or agent of the Corporation,
or shall be required by the Act to be otherwise signed or executed.

         SECTION 8. VICE PRESIDENTS: In the absence of the president, the vice
presidents in the order of their length of service as vice presidents, unless
otherwise determined by the board of directors, shall perform the duties of the
president, and when so acting shall have all the powers of and be subject to all
the restrictions upon that office. Any vice president may sign certificates for
shares, as well as any deeds, mortgages, contracts, or other instruments which
the board of directors has authorized to be executed, except in cases where the
signing and execution of such documents or instruments shall be expressly
delegated by the board of directors or these bylaws to some other officer or
agent of the Corporation or shall be required by the Act to be otherwise signed
or executed. A vice president shall perform such other duties as from time to
time may be assigned to him by the chief executive officer, the president, or
the board of directors.

                                       9
<PAGE>

         SECTION 9. SECRETARY: The secretary shall: (i) keep the minutes of the
meetings of shareholders, of the board of directors, and of all committees of
the board in one or more books provided for that purpose; (ii) see that all
notices are duly given in accordance with the provisions of these bylaws or as
required by law; (iii) be custodian of the seal of the Corporation and see that
the seal of the Corporation is affixed to all documents the execution of which
on behalf of the Corporation under its seal is duly authorized; (iv) keep a
register of the mailing address of each shareholder which shall be furnished to
the secretary by such shareholder; (v) sign, with the chief executive officer,
the president, or a vice president, certificates for shares, the issuance of
which shall have been authorized by resolution of the board of directors; (vi)
have general charge of the stock transfer books of the Corporation; (vii) keep
or cause to be kept in the State of North Carolina at the Corporation's
principal office a record of the Corporation's shareholders, giving the names
and addresses of all shareholders and the number and class of shares held by
each, and prepare or cause to be prepared a shareholder list prior to each
meeting of shareholders as required by the Act; (viii) maintain and authenticate
the books and records of the Corporation; (ix) with the assistance of the
treasurer and other officers, prepare and deliver to the Corporation's
shareholders such financial statements, notices, and reports as may be required
by N.C. Gen. Stat. Sections 55-16-20 and 55-16-21 (or their successors); (x)
prepare and file with the North Carolina Secretary of Revenue the annual report
required by N.C. Gen. Stat. Section 55-16-22 (or its successor); and (xi) in
general perform all duties incident to the office of secretary and such other
duties as from time to time may be assigned to him by the chief executive
officer, the president or the board of directors.

         SECTION 10. ASSISTANT SECRETARIES: In the absence of the secretary, the
assistant secretaries in the order of their length of service as assistant
secretary, unless otherwise determined by the board of directors, shall perform
the duties of the secretary, and when so acting shall have all the powers of and
be subject to all the restrictions upon the secretary. They shall perform such
other duties as may be assigned to them by the secretary, the chief executive
officer, the president, or the board of directors. Any assistant secretary may
sign, with the chief executive officer, the president or a vice president,
certificates for shares.

         SECTION 11. TREASURER: The treasurer shall be the chief financial
officer of the Corporation and shall: (i) have charge and custody of and be
responsible for all funds and securities of the Corporation; (ii) receive and
give receipts for monies due and payable to the Corporation from any source
whatsoever, and deposit all such monies in accordance with the provisions of
Section 4 of Article VII; (iii) prepare, or cause to be prepared, an annual
financial statement in accordance with Section 3 of Article IX; and (iv) in
general, perform all of the duties incident to the office of treasurer and such
other duties as from time to time may be assigned to him by the chief executive
officer, the president or the board of directors. The treasurer may sign, with
the chief executive officer, the president or a vice president, certificates for
shares.

         SECTION 12. ASSISTANT TREASURERS: In the absence of the treasurer, the
assistant treasurers, in the order of their length of service as assistant
treasurer, unless otherwise determined by the board of directors, shall perform
the duties of the treasurer, and when so acting shall have all the powers of and
be subject to all the restrictions upon the treasurer. They shall perform such
other duties as may be assigned to them by the treasurer, the chief executive
officer, the president, or the board of directors. Any assistant treasurer may
sign, with the chief executive officer, the president or a vice president,
certificates for shares.

         SECTION 13. ACTION RE: SECURITIES OF OTHER CORPORATIONS: Unless
otherwise directed by the board of directors, the President shall have power to
vote and otherwise act on behalf of the Corporation, in person or by proxy, at
any meeting of shareholders of or with respect to any action of shareholders of
any other corporation in which this Corporation may hold securities and
otherwise to 

                                       10
<PAGE>

exercise any and all rights and powers which this Corporation may
possess by reason of its ownership of securities in such other corporation.


                                   ARTICLE VII

                      CONTRACTS, LOANS, CHECKS AND DEPOSITS

         SECTION 1. CONTRACTS: The board of directors may authorize any officer
or agent to enter into any contract or to execute and deliver any instrument on
behalf of the Corporation, and such authority may be general or confined to
specific instances.

         SECTION 2. LOANS: No loans shall be contracted on behalf of the
Corporation and no evidences of indebtedness shall be issued in its name unless
authorized by a resolution of the board of directors. Such authority may be
general or confined to specific instances.

         SECTION 3. CHECKS AND DRAFTS: All checks, drafts or other orders for
payment of money issued in the name of the Corporation shall be signed by such
officers or agents of the Corporation and in such manner as shall from time to
time be determined by resolution of the board of directors.

         SECTION 4. DEPOSITS: All funds of the Corporation not otherwise
employed shall be deposited from time to time to the credit of the Corporation
in such depositories as the board of directors shall direct.


                                  ARTICLE VIII

                   CERTIFICATES FOR SHARES AND THEIR TRANSFER

         SECTION 1. CERTIFICATES FOR SHARES: Shares may, but need not, be
represented by certificates. If certificates are issued, they shall be in such
form as the board of directors shall determine; provided that, at a minimum,
each certificate shall state on its face: (i) the name of the Corporation and
that it is organized under the laws of North Carolina; (ii) the name of the
person to whom issued; and (iii) the number and class of shares and the
designation of the series, if any, the certificate represents. If the
Corporation issues certificates for shares of preferred stock, the designations,
relative rights, preferences, and limitations applicable to that class, and the
variations in rights, preferences, and limitations for each series within that
class (and the authority of the board of directors to determine variations for
future series) must be summarized on the front or back of each certificate;
alternatively, each certificate may state conspicuously on its front or back
that the Corporation will furnish the shareholder this information in writing
and without charge. These certificates shall be signed, either manually or in
facsimile, by the chief executive officer, the president, or any vice president,
and the secretary or any assistant secretary, the treasurer or any assistant
treasurer. They shall be consecutively numbered or otherwise identified and the
name and address of the persons to whom they are issued, with the number of
shares and date of issue, shall be entered on the stock transfer books of the
Corporation.

         SECTION 2. TRANSFER OF SHARES: Transfer of shares of the Corporation
shall be made only on the stock transfer books of the Corporation by the holder
of record, by his legal representative (who shall furnish proper evidence of
authority to transfer) or by his attorney (whose authority shall be evidenced by
a power of attorney duly executed and filed with the secretary), and only upon
surrender for cancellation of the certificates for such shares.

                                       11

<PAGE>

         SECTION 3. FIXING RECORD DATE: For the purpose of determining
shareholders entitled to receive notice of a meeting of shareholders, to demand
a special meeting, to vote, to take any other action, or to receive payment, or
for any other purpose, the board of directors may fix in advance a date as the
record date for any such determination of shareholders, such record date in any
case to be not more than seventy (70) days, and, in case of a meeting of
shareholders, not less than ten (10) days, before the date on which the
particular action requiring such determination of shareholders is to be taken.
If no record date is fixed for the determination of shareholders entitled to
notice of or to vote at a meeting of shareholders, or of shareholders entitled
to receive a distribution, the day before the first notice of the meeting is
mailed or the day on which the board of directors authorize the distribution, as
the case may be, shall be the record date for such determination of
shareholders.

         When a determination of shareholders entitled to notice of or to vote
at any meeting of shareholders has been made as provided in this Section, such
determination shall apply to any adjournment of such meeting unless the board of
directors fixes a new record date, which it must do if the meeting is adjourned
to a date more than 120 days after the date fixed for the original meeting.

         SECTION 4. LOST CERTIFICATES: The board of directors may authorize the
issuance of a new share certificate in place of a certificate claimed to have
been lost or destroyed, upon receipt of an affidavit of such fact from the
person claiming the loss or destruction. When authorizing the issuance of a new
certificate, the board of directors may require the claimant to give the
Corporation a bond in such sum as it may direct to indemnify the Corporation
against loss from any claim with respect to the certificate claimed to have been
lost or destroyed; or the board of directors may, by resolution reciting that
the circumstances justify such action, authorize the issuance of the new
certificate without requiring such a bond.

         SECTION 5. REACQUIRED SHARES: The Corporation may acquire its own
shares and shares so acquired constitute authorized but unissued shares.


                                   ARTICLE IX

                               GENERAL PROVISIONS

         SECTION 1. DISTRIBUTIONS: The board of directors may from time to time
declare, and the Corporation may make, distributions on its outstanding shares
in the manner and subject to the terms and conditions provided by the Act and by
the articles of incorporation.

         SECTION 2. SEAL: The corporate seal of the Corporation shall consist of
two concentric circles between which is the name of the Corporation and in the
center of which is inscribed "CORPORATE SEAL" or "SEAL," and which shall have
such other characteristics as the board of directors may determine.

         SECTION 3. RECORDS AND REPORTS: All of the Corporation's records shall
be maintained in written form or in another form capable of conversion into
written form within a reasonable time. The Corporation shall keep as permanent
records minutes of all meetings of its incorporators, shareholders, and board of
directors, a record of all actions taken by the shareholders or board of
directors without a meeting, and a record of all actions taken by a committee of
the board of directors in place of the board of directors.

         The Corporation shall keep a copy of the following records at its
principal office: (i) the articles of incorporation and all amendments to them
currently in effect; (ii) these bylaws and all amendments to them currently in
effect; (iii) resolutions adopted by its board of directors creating 


                                       12

<PAGE>

one or more classes or series of shares and fixing their relative rights,
preferences, and limitations (if shares issued pursuant to those resolutions are
outstanding); (iv) the minutes of all meetings of shareholders and records of
all actions taken by shareholders without a meeting during the past three years;
(v) all written communications to shareholders generally within the past three
years; (vi) the annual financial statements described below, prepared during the
past three years; (vii) a list of the names and business addresses of its
current directors and officers; and (viii) its most recent annual report
delivered to the North Carolina Secretary of Revenue (or Secretary of State, if
applicable).

         The Corporation shall prepare and make available to its shareholders
annual financial statements for the Corporation and its subsidiaries that: (i)
include a balance sheet as of the end of the fiscal year, an income statement
for that year, and a statement of cash flows for the year; and (ii) are
accompanied by either (x) a report of a public accountant on the annual
financial statements, or (y) a statement by the treasurer stating his reasonable
belief whether the annual financial statements were prepared on the basis of
generally accepted accounting principles (and, if not, describing the basis of
preparation) and describing any respects in which the statements were not
prepared on a basis of accounting consistent with the statements prepared for
the preceding year. These annual financial statements, or a written notice of
their availability, shall be mailed to each shareholder within 120 days after
the close of each fiscal year of the Corporation. On written request from a
shareholder who was not mailed the annual financial statements, the Corporation
shall mail to him the latest such statements.

         The Corporation shall also prepare and file with the North Carolina
Secretary of Revenue an annual report in such form as required by N.C. Gen.
Stat. Section 55-16-22, or its successor.

         SECTION 4. INDEMNIFICATION: Any person who at any time serves or has
served as a director or officer of the Corporation, or at the request of the
Corporation is or was serving as an officer, director, agent, partner, trustee,
administrator, or employee for any other foreign or domestic corporation,
partnership, joint venture, trust, employee benefit plan, or other enterprise,
shall be indemnified by the Corporation to the fullest extent from time to time
permitted by law in the event he is made, or is threatened to be made, a party
to any threatened, pending or completed civil, criminal, administrative,
investigative or arbitrative action, suit or proceeding and any appeal therein
(and any inquiry or investigation that could lead to such action, suit or
proceeding), whether or not brought by or on behalf of the Corporation, seeking
to hold him liable by reason of the fact that he is or was acting in such
capacity. In addition, the board may provide such indemnification for the
employees and agents of the Corporation as it deems appropriate.

         The rights of those receiving indemnification hereunder shall, to the
fullest extent from time to time permitted by law, cover (i) reasonable
expenses, including without limitation all attorneys' fees actually and
necessarily incurred by him in connection with any such action, suit or
proceeding, (ii) all reasonable payments made by him in satisfaction of any
judgment, money decree, fine (including an excise tax assessed with respect to
an employee benefit plan), penalty, or settlement for which he may have become
liable in such action, suit or proceeding; and (iii) all reasonable expenses
incurred in enforcing the indemnification rights provided herein.

         Expenses incurred by anyone entitled to receive indemnification under
this Section in defending a proceeding may be paid by the Corporation in advance
of the final disposition of such proceeding as authorized by the board of
directors in the specific case or as authorized or required under any provisions
in the bylaws or by any applicable resolution or contract upon receipt of an
undertaking by or on behalf of the director to repay such amount unless it shall
ultimately be determined that he is entitled to be indemnified by the
Corporation against such expenses.

                                       13

<PAGE>


         The board of directors of the Corporation shall take all such action as
may be necessary and appropriate to authorize the Corporation to pay the
indemnification required by this bylaw, including without limitation, to the
extent needed, making a good faith evaluation of the manner in which the
claimant for indemnity acted and of the reasonable amount of indemnity due him.

         Any person who at any time serves or has served in any of the aforesaid
capacities for or on behalf of the Corporation shall be deemed to be doing or to
have done so in reliance upon, and as consideration for, the right of
indemnification provided herein. Any repeal or modification of these
indemnification provisions shall not affect any rights or obligations existing
at the time of such repeal or modification. The rights provided for herein shall
inure to the benefit of the legal representatives of any such person and shall
not be exclusive of any other rights to which such person may be entitled apart
from the provisions of this bylaw.

         The rights granted herein shall not be limited by the provisions
contained in N.C. Gen. Stat. Section 55-8-51 (or its successor), provided,
however, that the Corporation shall not indemnify or agree to indemnify a
potential indemnitee against liability or expenses he may incur on account of
his activities which were at the time taken known or believed by the potential
indemnitee to be clearly in conflict with the best interests of the Corporation.

         The Corporation may purchase and maintain insurance on behalf of any
person who is or was a director, officer, employee or agent of the Corporation,
or is or was serving at the request of the Corporation as a director, officer,
employee or agent for any other foreign or domestic corporation, partnership,
joint venture, trust, employee benefit plan, or other enterprise, against any
liability asserted against him and incurred by him in any such capacity, or
arising out of his status as such, whether or not the Corporation would have the
power to indemnify him against such liability under the provisions of the Act or
these bylaws.

         SECTION 5. FISCAL YEAR: The fiscal year of the Corporation shall be
fixed by the board of directors.

         SECTION 6. AMENDMENTS: (a) The board of directors may amend or repeal
these bylaws, except to the extent otherwise provided in the articles of
incorporation, a bylaw adopted by the shareholders, or the Act, and except that
a bylaw adopted, amended or repealed by the shareholders may not be readopted,
amended or repealed by the board of directors if neither of the articles of
incorporation nor a bylaw adopted by the shareholders authorizes the board of
directors to adopt, amend, or repeal that particular bylaw or the bylaws
generally.

                  (b) The Corporation's shareholders may adopt, amend, alter,
change, or repeal any of these bylaws consistent with the provisions of Section
11 of Article III.

                  (c) A bylaw that fixes a greater quorum or voting requirement
for the board of directors may be amended or repealed: (i) if originally adopted
by the shareholders, only by the shareholders, unless the bylaw permits
amendment or repeal by the board of directors; or (ii) if originally adopted by
the board of directors, either by the shareholders or by the board of directors.

                  (d) A bylaw referred to in Subsection (c) above: (i) may not
be adopted by the board of directors by a vote of less than a majority of the
directors then in office; and (ii) may not itself be amended by a quorum or vote
of the directors less than the quorum or vote therein prescribed or prescribed
by a bylaw adopted or amended by the shareholders.


                                       14
<PAGE>

                  (e) A bylaw adopted or amended by the shareholders that fixes
a greater voting or quorum requirement for the board of directors may provide
that it may be amended or repealed only by a specified vote of either the
shareholders or the board of directors.

         SECTION 7. TIME PERIODS: In applying any provision of these bylaws
which requires an act to be done or not done a specified number of days prior to
an event or that an act be done during a period of a specified number of days
prior to an event, calendar days shall be used, the day of the doing of the act
shall be excluded and the day of the event shall be included.

         SECTION 8. OPT-OUT OF NORTH CAROLINA SHAREHOLDER PROTECTION ACT: The
provisions of the North Carolina Shareholder Protection Act, N.C. Gen. Stat.
ss.ss. 55-9-01 - 05, as presently enacted or hereafter amended, shall not be
applicable to the Corporation.

         SECTION 9. OPT-OUT OF NORTH CAROLINA CONTROL SHARE ACQUISITION ACT: The
provisions of the North Carolina Control Share Acquisition Act, N.C. Gen. Stat.
ss.ss. 55-9A-01 - 09, as presently enacted or hereafter amended, shall not be
applicable to the Corporation.

         SECTION 10. EMERGENCIES: In anticipation of or during an emergency, the
board of directors may: (i) modify lines of succession to accommodate the
incapacity of any director, officer, employee, or agent; and (ii) relocate the
principal office or designate alternative principal or regional offices, or
authorize the officers to do so.

         During an emergency: (i) notice of a meeting of the board of directors
need be given only to those directors whom it is practicable to reach and may be
given in any practicable manner, including by publication and radio; and (ii)
one or more officers present at a meeting of the board of directors may be
deemed to be directors for the meeting, in order of rank and within the same
rank in order of seniority, as necessary to achieve a quorum.

         SECTION 11. SEVERABILITY: Should any provision of these bylaws become
ineffective or be declared to be invalid for any reason, such provision shall be
severable from the remainder of these bylaws and all other provisions of these
bylaws shall continue to be in full force and effect.


ATTESTED:

/s/ Don T. Seaquist                                       Dated:  March 27, 1998
- ------------------------------------
Don T. Seaquist   
Secretary



                                      LEASE


                                       FOR


                                 ROYAL CENTER II





             LANDLORD:        Petula Associates, Ltd.,
                                       an Iowa corporation


             TENANT:          Embrex, Inc.
                                       a North Carolina corporation


<PAGE>


                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
<S>                                                                               <C>
1.          PREMISES                                                              1
2.          TERM                                                                  1
3.          RENT                                                                  2
4.          ADDITIONAL RENT                                                       3
5.          LANDLORD'S LIEN                                                       4
6.          USE                                                                   4
7.          PARKING AND COMMON AREAS                                              4
8.          UTILITIES                                                             5
9.          TENANT REPAIRS                                                        5
10.         LANDLORD REPAIRS                                                      6
11.         SIGNS AND ADVERTISING; USE OF NAME                                    6
12.         IMPROVEMENTS                                                          7
13.         FIXTURES AND INTERIOR ALTERATIONS                                     9
14.         LIENS                                                                 9
15.         INDEMNIFICATION                                                       10
16.         TENANT'S COMPLIANCE; INSURANCE REQUIREMENTS; WAIVER OF SUBROGATION    11
17.         CASUALTY DAMAGE                                                       12
18.         PASS THROUGH-PRORATED INSURANCE COSTS                                 13
19.         PASS THROUGH-PRORATED TAXES                                           13
20.         PASS THROUGH-OPERATING EXPENSE CHARGES                                14

<PAGE>


21.         ACCOUNTING FOR PASS THROUGH CHARGES                                   15
22.         LANDLORD LIABILITY                                                    16
23.         CARE OF PREMISES                                                      17
24.         QUIET ENJOYMENT                                                       18
25.         SURRENDER; HOLDING OVER                                               18
26.         ASSIGNMENT AND SUBLEASING                                             18
27.         SUBORDINATION; ATTORNMENT                                             19
28.         DEFAULT                                                               20
29.         ATTORNEY'S FEES                                                       21
30.         INSPECTION                                                            21
31.         CONDEMNATION                                                          21
32.         RIGHT TO RELOCATE                                                     21
33.         SECURITY DEPOSIT                                                      22
34.         NOTICES                                                               22
35.         HAZARDOUS MATERIALS; ENVIRONMENTAL COMPLIANCE                         23
36.         BROKER'S COMMISSIONS                                                  25
37.         MISCELLANEOUS                                                         25
38.         SPECIAL CONDITIONS, EXHIBITS AND ADDENDA                              26
</TABLE>


<PAGE>




STATE OF NORTH CAROLINA
                                             LEASE
COUNTY OF DURHAM


         THIS LEASE, made as of this 13 day of October, 1997, by and between
Petula Associates Ltd., hereinafter "Landlord", and Embrex, Inc., hereinafter
(whether one or more) "Tenant".

                                   WITNESSETH:

         Upon the terms and conditions hereinafter set forth, Landlord leases to
Tenant and Tenant leases from Landlord property hereinafter defined and referred
to as the Premises, all as follows:

         1.       PREMISES.  The property hereby leased to Tenant is:

                  That area shown on Exhibit A-1 (Floor Plan) consisting of
                  approximately 12,764 rentable square feet and located in Royal
                  Center II (the "Building") with an address at 4222 Emperor
                  Boulevard, Durham, North Carolina, the above-described leased
                  property being herein referred to as the Premises which
                  together with the common areas for the Building is also shown
                  on Exhibit A-3 (Site Plan). If Landlord or Tenant so requests,
                  at any time during the first six (6) months of the Term (as
                  hereinafter defined), the actual "as built" total square
                  footage of the Premises shall be measured by an architect
                  mutually acceptable to Landlord and Tenant in accordance with
                  BOMA (as hereinafter defined). If the amount of measured
                  rentable square feet is different from that stated above by
                  more than two percent (2%) of the above-stated amount, the
                  remeasured amount of rentable square feet, together with
                  resulting modifications of rent to be paid hereunder, shall be
                  set forth in a memorandum to be executed by Landlord and
                  Tenant. Landlord and Tenant agree to execute and deliver such
                  memorandum within ten (10) business days after the
                  measurement. In the event the measured rentable square feet
                  does not differ from the above-stated amount by more than two
                  percent (2%) of such amount, there shall be no modification to
                  the definition of the Premises or rent payable hereunder. The
                  cost of the remeasurement of the Premises shall be borne by
                  the party requesting same.

         2.       TERM. The term of this Lease shall be for a period of ten (10)
                  years commencing on the earlier to occur of: (i) Tenant's
                  occupancy of the Premises for the purpose of commencing its
                  business operations or (ii) November 14, 1997 (the
                  "Commencement Date"),

<PAGE>


and ending at midnight on the day before the tenth anniversary of the
Commencement Date (the "Term"). Tenant shall have the option to extend the Term
in accordance with Exhibit G attached hereto and incorporated herein by
reference. For purposes herein, a "Lease Year" shall be defined as a 365-day
period beginning on the Commencement Date or any anniversary thereof and a
"business day" shall be defined as any day other than Saturday, Sunday and any
day that is a legal or banking holding in North Carolina. Notwithstanding
anything contained herein to the contrary, in the event the Commencement Date is
a day other than the first day of a calendar month, the Term shall be extended
and shall expire on that date which is ten (10) full years from the first day of
the first full calendar month immediately following the Commencement Date (the
"Term Commencement Date"); provided, further, in the event the Commencement Date
is a day other than the first day of a calendar month, the first Lease Year
shall begin on the Commencement Date and shall expire on the first anniversary
of the Term Commencement Date and thereafter, each Lease Year shall commence and
expire on the anniversary of the Term Commencement Date.

         Promptly after the date of Landlord's receipt of this Lease as executed
by Tenant, Landlord shall proceed with due diligence to construct the Building
and shall use reasonable best efforts to deliver possession of the Premises in
its base building condition with Landlord's Work (as described in Exhibit B-1)
substantially completed to Tenant within five (5) days after this Lease has been
fully executed (the "Delivery Date"). Upon delivery of the Premises to Tenant,
the exterior of the Building and base building finishes shall be substantially
completed (i.e. the remaining work to be done to the exterior and interior of
the Building shall be of such a nature as will not materially interfere with
Tenant's undertaking of the Tenant Improvements (as hereinafter defined)) so
that Tenant and its approved contractor may enter into the Premises and commence
the construction of the Tenant Improvements. If for any reason whatsoever,
Landlord cannot deliver possession of the Premises to Tenant as of the Delivery
Date, this Lease shall not be void or voidable; no obligation of Tenant shall be
affected thereby; and neither Landlord nor Landlord's agent shall be liable to
Tenant for any loss or damage resulting therefrom; provided, however, that in
such event, the commencement and expiration dates of this Lease and all other
dates affected thereby may be revised by written notice from Landlord to Tenant
within thirty (30) days of the Delivery Date specified above to conform all
affected dates under this Lease to the date of Landlord's delivery of possession
to Tenant. Notwithstanding the foregoing, if Landlord is unable to deliver
possession of the Premises in its base building condition with Landlord's Work
substantially completed to Tenant on or before October 1, 1997 due to delays
within Landlord's reasonable control (and expressly excluding force majeure
delays and delays attributable to Tenant), Landlord agrees that Tenant shall be
entitled to one (1) day of free Minimum Rent for every two (2) days of delay in
delivering the Premises to Tenant beyond October 1, 1997.

         3. RENT. All rent payable by Tenant shall be without previous demand
therefor by Landlord, and without setoff or deduction. The minimum rent
("Minimum Rent") for the Term shall be the sum of One Million Three Hundred
Sixteen Thousand Nine Hundred Eighty-Nine and 52/100 Dollars ($1,316,989.52),
which rent shall be payable in advance in equal monthly installments as follows:


                                       2

<PAGE>



                       Rate Per              Monthly               Annual
   Lease Year         Rentable SF             Rent                  Rent
   ----------         -----------             ----                  ----
       1                $ 9.00              $ 9,573.00           $114,876.00
       2                $ 9.27              $ 9,860.19           $118,322.28
       3                $ 9.55              $10,158.02           $121,896.20
       4                $ 9.84              $10,466.48           $125,597.76
       5                $10.13              $10,774.94           $129,299.32
       6                $10.43              $11,094.04           $133,128.52
       7                $10.75              $11,434.42           $137,213.00
       8                $11.07              $11,774.79           $141,297.48
       9                $11.40              $12,125.80           $145,509.60
       10               $11.74              $12,487.45           $149,849.36

                                      Total Minimum Rent         $1,316,989.52

Each monthly installment of rent shall be payable on or before the first day of
each calendar month during the Term, unless the Term commences other than on the
first day of the month, in which event rent at the above rate pro-rated until
the end of that month shall be due and payable on the commencement date. In
addition to such remedies as may be provided under the default provisions of
this Lease, Landlord shall be entitled to a late charge of five percent (5%) of
the amount of the monthly rent if not received when due, and a charge of Twenty
Dollars ($20.00) or the maximum amount allowed by law, whichever is less, for
any check given by Tenant not paid when first presented by Landlord.
Notwithstanding the foregoing sentence, Tenant shall be entitled to one (1)
five-day grace period per Lease Year for the first late payment of monthly rent
without imposition of the foregoing late charge.

         4. ADDITIONAL RENT. In addition to rent, Tenant shall pay to Landlord,
at the same time as monthly installment payments to rent are made, a sum which
represents Tenant's proportionate share of insurance costs, taxes and operating
expense charges owed by Tenant pursuant to the terms of Sections 18, 19 and 20
of this Lease, respectively. The actual amount of additional rent due from
Tenant shall be adjusted on an annual basis as and when the actual amount of
tenant's proportionate share of insurance costs, taxes and operating expense
charges are determined, and if Tenant has underpaid, it shall, within thirty
(30) days after receipt of written demand therefor, together with such
supporting documentation as Tenant may reasonably request, pay the shortfall as
a lump sum payment, and if Tenant has overpaid, Landlord shall,


                                       3
<PAGE>


on a lump sum basis, reduce future monthly payments of additional rent for the
coming year so as to credit to Tenant the amount of overpayment.

         5. LANDLORD'S LIEN. [INTENTIONALLY DELETED]

         6. USE. The Premises may be used for laboratory, office, warehouse,
storage, and light assembly uses as is necessary for Tenant's business of
conducting live animal research on poultry for the purpose of developing
products which enhance poultry health and growth performance and for no other
purpose without Landlord's written consent first had and obtained.
Notwithstanding the foregoing, Tenant is expressly prohibited from producing or
selling poultry or any other animals for consumption. Tenant shall not use or
occupy nor permit the Premises to be used or occupied, nor do or permit anything
to be done in or on the Premises, in a manner which may (a) make void or
voidable any insurance in force with respect thereto; (b) result in any increase
in the premiums charged for warehouse insurance or cause Landlord to be unable
to obtain at regular rates fire or other insurance required to be maintained;
(c) cause structural damage to the Building, the Premises or any part thereof;
or (d) constitute a public or private nuisance; or (e) otherwise violate any
present or future law, ordinance, rule or requirement of any public authority
having jurisdiction, including, without limitation, any law, ordinance, rule or
requirement concerning or relating to Tenant's use, occupancy or alteration of
the Premises. If as a result of any act or neglect of Tenant, its employees,
agents, representatives, clients or visitors, or change in the manner in which
Tenant's business or operations are conducted at the Premises, any insurance
rate shall be increased over the existing rate and assessed against Landlord,
then and in that event, Tenant shall pay to Landlord within thirty (30) days
after receipt of written demand therefor, the amount of such increase as
additional rent.

         7. PARKING AND COMMON AREAS. For as long as Tenant affirmatively
complies with the terms of this Lease, Landlord grants to Tenant, its employees,
agents, representatives, customers, contractors and invitees, a nonexclusive
right to use during the Term, but subject to such reasonable and
non-discriminatory rules and regulations as Landlord may enact in accordance
with the terms hereof, the common areas shown on Exhibit A-3 (Site Plan) and
which areas are or shall be designated by Landlord and are acknowledged to be
for use of such persons along with others similarly entitled, for parking, and
for ingress and egress between the Premises and other portions of the common
areas as shown on Exhibit A-3, which may include adjoining streets, sidewalks,
and highways. Tenant's employees shall park only in areas designated from time
to time by Landlord within the Royal Center II parking areas as described on
Exhibit A-3 attached hereto, and not in any other parking area. Landlord shall
make available to Tenant three (3) parking spaces per 1,000 rentable square feet
of the Premises. Common areas include, without limitation, parking areas and
entrances and exits thereto, driveways and truck serviceways, sidewalks,
landscaped areas, business park entrance areas and other areas and facilities
provided for the common or joint use and benefit of occupants of the Building
and others, their respective employees, agents, representatives, customers,
contractors and invitees. Landlord reserves the right, from time to time, to
reasonably alter the common areas, to exercise control and management of the
common areas and to establish, modify, change and enforce such reasonable and
nondiscriminatory rules and regulations as Landlord in its


                                       4
<PAGE>


discretion may deem desirable for the management of the Building, the business
park, the common areas or any part thereof as long as Tenant's use and enjoyment
of the common areas is not materially diminished and the operating expenses with
respect to any common areas are not materially increased. In using any part of
the common areas, Tenant shall not permit anything which may impede the free
flow of traffic through such common areas, endanger persons or property or
encroach on the loading or unloading, service and parking areas of any other
tenant. Rules and Regulations which apply in part to Tenant's use of the common
areas are set forth in Exhibit C.

         8. UTILITIES. Tenant shall procure for its own account and shall pay
all charges for water, telephone, electricity, gas, sewage, and other utilities
used by Tenant at or in the Premises, and Landlord agrees at all times to
provide Tenant with access to such utilities for the purpose of Tenant
maintenance, repair or replacement of such facilities or systems. Tenant shall
be responsible for separate meters for all utilities used at or in the Premises.
To the extent that any service or utility used by Tenant at or in the Premises
is not separately metered, Tenant agrees to pay as additional rent and as a
monthly charge its "pro rata share" of the charges due for such service or
utility, unless otherwise agreed in writing by Landlord, Tenant and any other
affected tenant. Tenant's "pro-rata share" shall be determined in accordance
with the terms of Section 18 for calculating the same, except that the
denominator for the computation shall be the square footage of all premises
affected or served by the particular meter.

         9. TENANT REPAIRS. Other than those items specified for repair,
replacement and maintenance by Landlord in Section 10 hereof, Tenant shall be
responsible for the repair, replacement and maintenance in good order and
condition of all parts and components of the Premises, together with all
systems, fixtures or equipment therein or appurtenant thereto, including,
without limitation, interior surfaces, flooring, wiring, plumbing, heating and
air conditioning equipment, trade fixtures, loading area components (including,
without limitation, overhead doors, bumpers, seals and levelers) and other
facilities, systems or equipment, whether or not originally installed by
Landlord or Tenant in good condition and repair, ordinary wear and tear
excepted; provided, however, Tenant shall be solely responsible for any unusual
or extraordinary wear and tear resulting from Tenant's use of the Premises.
Tenant shall be responsible for maintenance and replacement of all broken plate
glass and windows (unless breakage or damage results from settling of the
building or faulty initial construction undertaken by Landlord) and of all
lights and ballasts. Tenant shall maintain all lighting serving the interior of
the Premises in good working order at all times during the Term. In connection
with the day-to-day maintenance and repair of the heating and air conditioning
systems and equipment at the Premises, Tenant agrees to enter into and maintain
(for the Term) a maintenance contract with a reputable company offering
maintenance and repair services reasonably acceptable to Landlord, this contract
to be subject to the specifications set forth in Exhibit D. Tenant shall provide
Landlord with satisfactory evidence that it has entered into and maintained the
aforesaid maintenance contract upon Landlord's request therefor. If, after
written notice from Landlord, Tenant fails to repair or maintain any component,
system, fixture or facility at the Premises which Tenant is obligated to repair
or maintain, then Landlord may, at Landlord's option,


                                       5
<PAGE>


repair or maintain the same, and Tenant shall, upon demand by Landlord,
reimburse Landlord forthwith for the total costs of such repairs.

         10. LANDLORD REPAIRS. Landlord shall be responsible for maintenance of
Landlord's Work and the maintenance and cleaning of the common areas of the
Building and adjacent to the Building; provided, however, if any element of
Landlord's Work is either materially altered by Tenant during its upfitting of
the Premises for non-office use without Landlord's prior written consent to be
granted or withheld in Landlord's sole discretion, or damaged as a result of
Tenant's non-office use, Tenant shall be solely responsible for the maintenance
and repair of such item. Except as otherwise set forth in Exhibit B-1,
Landlord's Work shall not include interior doors, windows or other components of
the Premises which are not load bearing. There shall be no allowance to Tenant
for a diminution of rentals value and no liability on the part of Landlord for
inconvenience, annoyance or injury to business arising from Landlord or others
making any construction or repair to the Premises, the Building, the common
areas or an adjoining premises, and no liability on the part of Landlord for
failure of Landlord or others, to make any repairs, alterations, additions or
improvements in or to any portion of the Premises, the Building or common areas;
provided, however, if such construction or failure denies Tenant the use of the
Premises for the normal conduct of Tenant's business for a period of three (3)
consecutive business days, Tenant's obligation to pay Minimum Rent shall abate
until such time as the Premises is available to Tenant for the normal conduct of
its business, as reasonably determined by Landlord. Landlord shall not be liable
to Tenant for any damage caused to Tenant and its property due to the Premises
or the Building, or any part or appurtenance thereof, being improperly
constructed or being or becoming out of repair, or arising from the leaking of a
pipe, facility or system for gas, water, sewage, steam, electricity or other
utility; provided, Landlord shall, subject to the Section 22 hereof, be liable
for any actual and direct damage to Tenant or the Premises caused by Landlord's
failure to repair any item of Landlord's Work within a reasonable time after
receipt of written notice from Tenant describing with specificity such repair
and Tenant specifically waives any right to pursue consequential damages arising
from Landlord's failure to repair such item. Tenant shall immediately report to
Landlord any defective condition in or about the Premises known to Tenant, and
if such defect is not so reported and such failure results in other damage,
Tenant shall be liable for such other damage. Regardless of any obligation
otherwise imposed upon Landlord, Tenant shall pay the cost of any repairs or
damage resulting from the negligence or the unlawful or willful acts of its
employees, representatives or visitors.

         11. SIGNS AND ADVERTISING; USE OF NAME. Without first obtaining the
prior approval of Landlord (and after submitting such design specifications,
prepared at Tenant's sole cost and expense, as Landlord may require), Tenant
shall not permit the installation, painting and display of any sign, plaque,
lettering or advertising material of any kind on or near the exterior of the
Premises, or in the interior thereof that will be visible from the exterior. Any
such installation of a sign or other advertising by Tenant shall be installed in
accordance with Exhibit F attached hereto, in compliance with applicable law and
installed and maintained by Tenant at its sole cost and expense and shall be
removed by Tenant at the expiration or sooner termination of this Lease,
whereupon Tenant shall repair any damage caused to the Premises or


                                       6
<PAGE>


Building by such removal. Tenant shall keep all approved signage and other
material in good working order clearly illuminated during business hours. Tenant
shall not have any property right or interest in any name or distinctive
designation which may become associated with the Building or the common areas of
which the Building may be a part. Landlord shall retain all property rights in,
and the exclusive right of use of, such name or designation.

         12. IMPROVEMENTS. Tenant's preliminary plans and specifications
relating to the Tenant improvements to be constructed in the initially
configured Premises (the "Preliminary Plans") are currently under review by
Landlord. Once the Preliminary Plans are approved by Landlord, Tenant shall
prepare the final plans and specifications relating to the Tenant improvements
(the "Final Plans") and shall thereafter deliver the Final Plans to Landlord for
its review and approval. Landlord shall not unreasonably withhold or delay its
approval of the Final Plans and agrees to provide Tenant with notice of any
objections to such plans within fifteen (15) days after Landlord's receipt of
same; provided , however, so long as the Final Plans are consistent with and
substantially similar to the Preliminary Plans previously approved by Landlord,
the Final Plans will be deemed approved by Landlord. Upon approval by Landlord
of the Final Plans, they shall be attached as Exhibit B to this Lease and made a
part hereof. The improvements shown on such approved plans as they may be
modified with Landlord's consent (not to be unreasonably withheld or delayed)
and not otherwise included in Landlord's Work are referred to in this Lease as
the "Tenant Improvements."

         With respect to the design and construction of the Tenant Improvements,
Tenant agrees to undertake the work in accordance with the following:

         (i) Tenant agrees to cooperate fully with Landlord for the purpose of
coordinating the construction of the Tenant Improvements with the construction
of the Building;

         (ii) All contractors selected by Tenant to construct the Tenant
Improvements shall require the express approval of Landlord (such approval not
to be unreasonably withheld or delayed) prior to the commencement of any such
work;

         (iii) Tenant shall contract directly with the approved contractor to
construct the Tenant Improvements;

         (iv) Tenant agrees to commence the construction of the Tenant
Improvements within fifteen (15) days after Tenant's receipt of all necessary
building permits and the construction of the Tenant Improvements shall be fully
coordinated with the construction of the Building and otherwise scheduled
appropriately; and

         (v) Tenant agrees to complete the Tenant Improvements within one
hundred twenty (120) days after delivery of the Premises from Landlord to
Tenant. Landlord and Tenant each agree to use reasonable best efforts to ensure
that their respective contractors will coordinate the job site conditions with
the other's contractor with respect to job site security, staging of equipment
and materials so as not to impede work in progress and protection of work in
place.



                                       7
<PAGE>

         It is the intent of the parties hereto that the construction of the
Tenant Improvements in the Premises shall be fully coordinated with the
construction of the Building and Landlord's Work and accordingly, undertaken
concurrently with the completion of the Building's shell in accordance with the
reasonable requirements of Landlord or its representatives.

         Provided Tenant is not in default hereunder beyond any applicable grace
or cure period, Landlord agrees to provide to Tenant an allowance of up to
Twenty-Five Dollars ($25.00) per rentable square foot of the Premises (the
"Tenant Allowance") to be applied to the cost of the Tenant Improvements.
Provided the amount requested by Tenant is not in dispute, the Tenant Allowance
shall be paid by Landlord to Tenant monthly on a date fixed by Landlord. Such
disbursement shall be contingent on Tenant furnishing to Landlord ten (10) days
prior to said disbursement date such invoices and other documents as may be
reasonably requested by Landlord relative to the design and construction of the
Tenant Improvements which evidence Tenant's payment of an amount equal to at
least $25.00 per rentable square foot of the Premises toward such costs, at
which time Landlord agrees to disburse the full Tenant Allowance to Tenant.
Tenant shall be responsible for any cost of the Tenant Improvements in excess of
the Tenant Allowance. Notwithstanding anything contained herein to the contrary,
the Tenant Allowance shall be reduced by an amount equal to one-half (1/2) of
the reasonable cost of the demising wall to be constructed by Landlord within
the Building.

         Landlord will charge Tenant fees not to exceed two percent (2%) of the
costs of the design and construction of the Tenant Improvement in the aggregate
for reviewing the Tenant Improvement plans and specifications, inspecting the
construction of the Tenant Improvements, and for otherwise coordinating the
Tenant Improvements with the construction of the Building. These fees chargeable
to Tenant may be deducted from the Tenant Allowance and in any event are payable
within thirty (30) days after substantial completion of any major phase of the
Tenant Improvements.

         In the event the projected cost of the Tenant Improvements exceeds the
Tenant Allowance, Tenant, upon written request from Landlord, shall provide to
Landlord such information regarding Tenant's financial condition as shall
satisfy Landlord, in its reasonable discretion, that Tenant has the financial
capability to pay such excess cost.

         Landlord or Landlord's agents have made no representations or promises
with respect to the Premises or the Building except as expressly set forth
herein. The taking of possession of the Premises by Tenant shall be conclusive
evidence as against Tenant, that Tenant accepts the same "as is" and "where is"
and that the Premises and Building were in good condition at the time when
possession was taken by Tenant. Landlord may at any time construct additional
buildings or improvements in any part of the common areas and may remodel or
remove the Building or any existing building in any part of the common areas.
Any sidewall of the Premises may be used by Landlord as a "party wall" for other
buildings or improvements. However, in connection with Landlord's construction
of any additional buildings or improvements, Landlord shall not unreasonably
interfere with Tenant's use and occupancy of the Premises or impair Tenant's
rights under this Lease. Notwithstanding anything contained


                                       8
<PAGE>


herein to the contrary, upon the expiration or earlier termination of the Term
of this Lease or Tenant's vacating the Premises, Tenant shall, at its sole cost
and expense, restore the Premises to its "base building condition"; provided,
however, in the event Tenant elects to extend the term of this Lease pursuant to
Exhibit G hereof, Tenant shall have no obligation to restore the Premises to its
base building condition and instead, may return the Premises to Landlord in its
"as-is" condition. For purposes hereof, "base building condition" shall mean the
condition of the Premises with Landlord's Work completed together with such
other Tenant Improvements as Landlord directs be left at the Premises; provided,
however, Tenant's restoration obligations with respect to the slab floor in the
Premises shall be limited to restoring the floor to a level slab of commercially
reasonable tolerances (i.e. one-eighth of an inch per ten feet). Within ten (10)
business days after Tenant's request for same (such request to be made no
earlier than sixty (60) days prior to the expiration or earlier termination of
the Term), Landlord shall provide Tenant with a list of those Tenant
Improvements which Landlord directs be left at the Premises upon the expiration
of the Term.

         13. FIXTURES AND INTERIOR ALTERATIONS. Tenant, with Landlord's prior
written consent (not to be unreasonably withheld or delayed) but at Tenant's own
expense, may from time to time during the Term make interior alterations in and
to the Premises which it may deem necessary or desirable provided that in no
case may it affect the structural integrity of the Premises or the Building. Any
such work shall be done in a good workmanlike manner and in accordance with
applicable law and shall not result in any claim or lien against Landlord or its
property. All permanent improvements or alterations shall belong to Landlord and
become a part of the Premises upon the expiration or sooner termination of this
Lease, unless Landlord, when its consent is given, requests Tenant to remove
such improvements or alterations at Tenant's sole expense, whereupon Tenant
shall also cause to be repaired any damage to the Premises resulting from the
removal. Tenant shall be entitled to claim the depreciation attributable to all
leasehold improvements within the Premises constructed and paid for by Tenant.
Tenant may construct or install in the Premises, all racks, counters, shelves,
mirrors, chairs, and other trade fixtures and equipment in accordance with
applicable law as may be necessary or convenient for Tenant's business, which
racks, counters, shelves, mirrors, chairs, and other trade fixtures and
equipment shall at all times be and remain the property of Tenant, and Tenant
shall have the right to remove all or any part of the same from the Premises at
any time prior to the expiration or sooner termination of this Lease, provided
nevertheless that Tenant shall repair any damage to the Premises resulting from
installation or removal.

         14. LIENS. Tenant shall keep the Premises and the Building free from
any liens arising out of any work performed, materials furnished or obligations
incurred by or on behalf of Tenant, and Tenant hereby agrees to indemnify and
hold Landlord, its agents, employees, contractors, officers, directors, partners
and shareholders harmless from any and all liability, cost or expense for such
liens. Tenant shall cause any such lien imposed to be released of record by
payment or bonding within twenty (20) days after the earlier of the imposition
of the lien or a written request by Landlord therefor. If Tenant fails to remove
any lien within the prescribed twenty (20) day period, then Landlord may do so
at Tenant's expense, including costs


                                       9
<PAGE>


and reasonable attorneys' fees actually incurred at standard rates, which
expense shall be due as additional rent hereunder.

         15. INDEMNIFICATION. Except to the extent caused by the negligence or
willful misconduct of Landlord or its employees, agents or representatives and
to the extent Landlord does not receive proceeds pursuant to its insurance
policies, Tenant shall indemnify and hold harmless Landlord, its agents,
representatives, successors or assigns, from and against any and all losses,
damages, liabilities, claims, penalties, costs or expenses (including reasonable
attorney's fees actually incurred at standard rates), whether caused by Tenant
or by its agents, servants, employees, independent contractors or licensees,
occasioned by, arising or resulting from or growing out of (a) Tenant's use or
occupancy of the Premises, or from the conduct of Tenant's business, or from any
activity, work or things done, permitted or suffered by Tenant in or about the
Premises; (b) the breach or default in the performance of any obligation on
Tenant's part to be performed under the terms of this Lease or arising from any
act or omission of Tenant; or (c) any alleged or actual violation of any
Environmental Law (as defined below), any unsafe or improper use or storage of
any Hazardous Substance (as defined below) or any condition created by or
arising therefrom including any actual or threatened pollution or contamination
at or about the Premises or the Building, whether or not due to negligence, an
omission or a willful act.

         Except to the extent caused by the negligence or willful misconduct of
Tenant or its employees, agents or representatives and to the extent Tenant does
not receive proceeds pursuant to its insurance policies, Landlord shall
indemnify and hold harmless Tenant, its agents, representatives, successors or
assigns, from and against any and all losses, damages, liabilities, claims,
penalties, costs or expenses (including reasonable attorney's fees actually
incurred at standard rates), whether caused by Landlord or by its agents,
servants, employees or licensees occasioned by, or arising or resulting from or
growing out of (a) Landlord's use of or entry upon the Premises or the Building,
or from the conduct of Landlord's business, or from any activity, work or thing
done by Landlord in or about the Premises or the Building; (b) the breach or
default in the performance of any obligation on Landlord's part to be performed
under the terms of this Lease or arising from any act or omission of Landlord or
its agents, representatives or employees; or (c) any actual violation of any
Environmental Law, any unsafe or improper use or storage of any Hazardous
Substance by Landlord or any condition created by or arising therefrom,
including any actual pollution or contamination at or about the Building by
Landlord whether or not due to negligence, an omission or a willful act.

         The indemnification provisions contained herein shall not be deemed to
be limited by the limits of any insurance policies required under this Lease and
shall survive the expiration or sooner termination of this Lease. The
indemnifying party shall defend any suit, action or proceeding commenced or
brought against the other party in connection with any indemnity or obligation
of the indemnifying party contained in this Section regardless of any alleged
fault or cause and the indemnifying party shall employ legal counsel reasonably
satisfactory to the other party to defend such suits, actions or proceedings.
The indemnifying party shall deliver to the other party copies of the documents
served in any such suit, action or proceeding and, whenever


                                       10
<PAGE>


requested by such other party, shall advise as to the status of such suit,
action or proceeding. If the indemnifying party fails to defend diligently any
such suit, action or proceeding, or if such other party elects to defend by
written notice to the indemnifying party at any time, such other party shall
have the right (but not the obligation) to defend the same at the indemnifying
party's expense. The indemnifying party shall not settle any such suit, action
or proceeding without the other party's prior written consent. The indemnifying
party shall give timely notice of such suit, action or proceeding and the claims
thereof to the other party and each insurer issuing an insurance policy required
under this Lease.

         16. TENANT'S COMPLIANCE; INSURANCE REQUIREMENTS; WAIVER OF SUBROGATION.
Tenant shall comply with all applicable laws, ordinances and regulations
affecting the Premises, including the Rules and Regulations set forth in Exhibit
C and any other nondiscriminatory rules for tenants as may be developed from
time to time by Landlord and delivered to Tenant or posted on the Premises.
Tenant shall maintain and care for its personal property and trade fixtures
located in the Premises, insure such personal property and fixtures in all
respects, and shall neither have nor make any claim against Landlord for any
loss or damage to the same, regardless of the cause therefor except to the
extent of the negligence or willful misconduct of Landlord or its agents or
employees. Throughout the Term, Tenant, at its sole cost and expense, shall keep
or cause to be kept for the mutual benefit of Landlord and Tenant the following
insurance: (a) commercial general liability insurance naming Landlord, and
Landlord's agent, Tri Properties, Inc., as an additional insured against any and
all claims for bodily injury and property damage occurring in or about the
Premises arising out of Tenant's use and occupancy of the Premises, such
insurance to have a combined single limit coverage of not less than $1,000,000
per occurrence with a $2,000,000 aggregate limit and excess umbrella liability
insurance in the amount of $2,000,000 (If Tenant has other locations that it
owns or leases, the policy shall include an aggregate limit per location
endorsement) and such insurance to be primary and non-contributing to any
insurance available to Landlord and Landlord's insurance shall be in excess
thereto, and in no event shall the limits of such insurance be considered as
limiting the liability of Tenant under this Lease; (b) personal property
insurance insuring all equipment, trade fixtures, inventory, fixtures and
personal property located on or in the Premises for perils covered by the causes
of loss--special form (all risk), together with coverage for flood, earthquake
and boiler and machinery (if applicable), such insurance to be written on a
replacement cost basis in an amount equal to one hundred percent (100%) of the
full replacement value of the aggregate of the foregoing property; (c) workers'
compensation insurance in accordance with statutory law and employers' liability
insurance with a limit of not less than $100,000 per employee and $500,000 per
occurrence; and (d) such other insurance as Landlord reasonably deems necessary
and consistent with the requirements of other similar tenants in the Business
Park or required by Landlord's beneficiaries or mortgagees of any deed of trust
or mortgage encumbering the Premises. The policies required to be maintained by
Tenant shall be with companies rated AX or better in the most current issue of
Best's Insurance Reports. Insurers shall be licensed to do business in the State
of North Carolina and domiciled in the United States of America. Any deductible
amounts under any insurance policies required hereunder shall not exceed
$20,000, except for Tenant's flood and earth movement insurance which may
contain deductible amounts up to $50,000. Certificates of insurance (or
certified


                                       11
<PAGE>


copies of the policies if required by Landlord) shall be delivered to Landlord
prior to the commencement date and thereafter at least thirty (30) days prior to
the expiration date of the old policy. Landlord and Tenant agree that all
contractors working at or within the Premises at the direction of either
Landlord or Tenant shall be adequately insured in a commercially reasonable
manner. Tenant shall have the right to provide insurance coverage which it is
obligated to carry pursuant to the terms hereof in a blanket policy, provided
such blanket policy expressly affords coverage to the Premises and to Landlord
directly as required by this Lease. Each policy of insurance shall provide
notification to Landlord at least thirty (30) days prior to any cancellation or
modification resulting in a reduction of insurance coverage. Landlord and Tenant
hereby release the other from any and all liability or responsibility to the
other or anyone claiming through or under them, by way of subrogation or
otherwise, from any loss or damage to property caused by fire or any other
perils insured under policies of insurance covering such property (but only to
the extent of the insurance proceeds payable under such policies), even if such
loss or damage is attributable to the fault or negligence of the other party, or
anyone for whom such party may be responsible, including any other tenants,
owners or occupants of the Building. The foregoing notwithstanding, this mutual
release shall be applicable and in force and effect only to the extent lawful at
the time any claim is made, and in any event only with respect to loss or damage
occurring during such times as the releasor's policies shall contain a clause or
endorsement providing that any such release shall not adversely affect or impair
said policies or prejudice the right of the releasor to recover thereunder, and
then only to the extent of insurance proceeds payable under such policies.
Landlord and Tenant shall request its insurance carriers to include in its
policies such a clause or endorsement. If additional cost shall be charged
therefor, the party responsible for procuring such insurance shall pay such
additional costs.

         17. CASUALTY DAMAGE. If the Premises, or any part thereof, shall be
damaged by fire or other casualty, Tenant shall give prompt written notice
thereof to Landlord. In case the Premises shall be so damaged by fire or other
casualty that substantial alteration or reconstruction of the Premises shall, in
Landlord's sole opinion, be required, Landlord may, at its option, terminate
this Lease and the term and estate hereby granted, by notifying Tenant in
writing of such termination within sixty (60) days after the date of damage, in
which event the rent shall be abated as of the date of damage. If Landlord does
not elect to terminate this Lease, Landlord shall within ninety (90) days after
the date of such damage commence to repair and restore the Premises and shall
proceed to restore the Premises (except that Landlord shall not be responsible
for delays beyond its control) to substantially the same condition in which it
was immediately prior to the happening of the casualty, except that Landlord
shall not be required to rebuild, repair, or replace any part of Tenant's
furniture, furnishings, fixtures or equipment removable by Tenant, and such work
shall not in any event exceed the scope of the work done by Landlord in
originally constructing the Premises nor shall Landlord in any event be required
to spend for such work an amount in excess of the insurance proceeds actually
received by Landlord as a result of the fire or other casualty. For the period
of restoration, rent shall abate as of the date of damage, unless Tenant is able
to continue its occupancy of the Premises during restoration whereupon rent
shall be adjusted and prorated in the proportion which the area of unusable
lease space bears to the total Premises. In any event, except to the extent of


                                       12
<PAGE>


Landlord's gross negligence or willful misconduct, Landlord shall not be liable
for any inconvenience or annoyance to Tenant, injury to the business of Tenant,
loss of use of any part of the Premises by Tenant or loss of Tenant's personal
property resulting in any way from such damage or the repair thereof. If the
Premises or any other portion of the Building are damaged by fire or other
casualty resulting from the omission, fault or negligence of Tenant or any of
Tenant's agents, employees, or invitees, rent due hereunder shall not be abated
or diminished during the repair of such damage and Tenant shall be liable to
Landlord for the cost and expense of the repair and restoration of the Premises
and Building caused thereby to the extent such cost and expense is not covered
by insurance proceeds.

         18. PASS THROUGH--PRORATED INSURANCE COSTS. For the Term, Landlord
shall keep the Building containing the Premises insured against loss or damage
by fire with extended coverage endorsement in an amount sufficient to prevent
Landlord from becoming a co-insurer under the terms of applicable policies, but,
in any event, in an amount not less than ninety (90%) percent of the full
insurable value of the Building as determined from time to time. Tenant agrees
to pay Landlord in advance monthly as additional rent its "pro rata share" (as
defined below) of the estimated premiums and costs of such Landlord insurance
throughout the Term, and any renewals or extensions hereof. Tenant's "pro rata
share" of such insurance costs shall mean that percentage found by dividing the
agreed to rentable square footage of the Premises by the agreed to rentable
square footage of the Building(s) (in which the Premises is located) subject of
the insurance. In this instance, the "pro rata share" computation is as follows:
12,764 rentable square feet of the Premises divided by 32,713 rentable square
feet of the Building equals 39.0%. This computed monthly charge estimated by
Landlord shall be paid by Tenant until such time when the charge shall be
adjusted to reflect actual insurance costs for the year. If the reconciliation
of the charges shows a deficiency, such deficiency shall be paid by Tenant to
Landlord within thirty (30) days after receipt of written demand therefor by
Landlord; if it shows a credit, the credit will be applied in a lump sum against
Tenant's next rent payment. For the first calendar year beginning with January
1, 1998, Tenant's estimated proportionate share of the premiums and costs of
such Landlord insurance shall be Three cents ($.03) per square foot for each
rentable square foot of the Premises per annum, payable in advance in equal
monthly installments.

         19. PASS THROUGH--PRORATED TAXES. Tenant shall pay Landlord in advance
monthly as additional rent its "pro rata share" (as determined in accordance
with the terms of Section 18 hereof) of any sale, use and/or occupancy tax
imposed on rents collected by Landlord (other than City, State or Federal Income
and Franchise Taxes) or any tax on rents in lieu of ad valorem taxes,
notwithstanding that any such tax may be levied or assessed against Landlord.
Tenant further agrees to pay Landlord its "pro rata share" (as determined in
accordance with the terms of Section 18) of ad valorem or any other property tax
imposed upon the Building(s) (of which the Premises is a part) subject to the
tax, regardless of the taxing authority or authorities levying the same.
Furthermore, Tenant shall make timely payments of all ad valorem taxes and
assessments made against Tenant's stock of merchandise, furniture, furnishings,
trade fixtures, equipment, supplies and other property located on or used in
connection with the Premises and of all privilege and business licenses, taxes
and similar charges


                                       13
<PAGE>


for which Tenant may be responsible. If the assessed value of the Building in
which the Premises are located is increased by a taxing authority because of
alterations or modifications to the Building made at Tenant's request or made by
Tenant, then the additional taxes attributable to such increase in valuation
shall be the sole responsibility of Tenant, and shall be included monthly as
additional rent to be paid by Tenant. For the first calendar year beginning with
January 1, 1998, the amount of Tenant's estimated share of ad valorem taxes
shall be Eighty cents ($.80) per square foot for each rentable square foot of
the Premises per annum, payable in advance in equal monthly installments.

         20. PASS THROUGH--OPERATING EXPENSE CHARGES. Landlord will operate and
maintain the common areas of the Building, and related areas and facilities
referred to in Section 7 above, all as shown in Exhibit A-3 (Site Plan). For the
Term or any extension hereof, Tenant shall pay Landlord as additional rent a
minimum sum as a common areas operating expense charge equal to Sixty-Six cents
($0.66) per square foot for each rentable square foot of the Premises, per
annum, namely the sum of Eight Thousand Four Hundred Twenty-Four and 24/100
Dollars ($8,424.24) which shall be due and payable in monthly installments of
Seven Hundred Two and 02/100 Dollars ($702.02) each, in advance as rent is due.
In addition, Tenant shall pay Landlord as additional rent Tenant's proportionate
share of the Business Park fee payable by Landlord equal to Four and one-half
cents ($.045) per square foot for each rentable square foot of the Premises per
annum, payable in advance in equal monthly installments. In the event that the
actual operating expenses for the common areas as prorated shall exceed the
minimum sum shown above, Tenant shall pay its "pro rata share" (as determined in
accordance with the terms of Section 18 or if with respect to an operating
expense concerning the business park common areas, then a "business park
amenities pro rata share" determined from a percentage found by dividing the
agreed to rentable square footage of the Premises by the rentable square footage
of all benefiting buildings within the business park) of any such increase, as a
monthly charge in advance as rent is due. As used herein, the term "operating
expense" shall mean and include all actual operating costs concerning the
operation or maintenance of the common areas as determined by standard
accounting practices and shall include by way of illustration, but not limited
to: property management fees, ad valorem real and personal property taxes, legal
fees and other costs incurred in connection with protesting tax assessment in
good faith, hazard and liability insurance premiums, common area utilities,
common area maintenance services, common area facilities, business park
amenities, landscaping, snow removal, asphalt and pavement repair, labor,
materials, supplies, equipment and tools, permits, licenses and inspection fees.
The term "operating expense" shall not include depreciation on the Building in
which the Premises are located or equipment therein (except for the reasonable
amortization of the costs for capital investment items which are purchased and
installed for the purpose of reducing "operating expenses" but only to the
extent of actual reductions in the operating expenses), interest, executive
salaries or real estate broker commissions. The term "operating expenses" shall
also not include the following items: (a) repairs or other work occasioned by
fire, windstorm or other casualty, the costs of which are reimbursed to Landlord
by insurers or by others, and repairs or other work occasioned by condemnation
proceedings, the costs of which are reimbursed by governmental authorities or by
others; (b) costs incurred in renovating or otherwise improving the Building for
tenants or other


                                       14
<PAGE>


occupants of the Building; (c) costs of correcting defects in the construction
of the Building (including latent defects in the Building) or in equipment,
except that for the purposes of this subsection (c) costs which are not
occasioned by construction defects but rather result from general maintenance
and repair or ordinary wear and tear and use shall not be deemed defects; (d)
Landlord's cost of electricity and other utilities and services furnished by
Landlord for which Landlord is entitled to be reimbursed by tenants (whether or
not actually collected by Landlord) as a separate additional charge or rental;
(e) costs (i) incurred due solely to a material violation by Landlord of the
terms and conditions of any lease pertaining to the Building or of any valid,
applicable legal requirement, building code, regulation, or law, or (ii)
incurred due solely to the Building being in material violation of any such
legal requirement, building code, regulation or law which exists as of the date
construction of the Premises commences or (iii) incurred due to an increase in
the rate of insurance on the Building or its contents which is caused solely by
the act of any tenant other than Tenant; (f) overhead and profit increment paid
to subsidiaries or affiliates of Landlord or its partners for services on or to
the Building, to the extent that such costs of such services exceed competitive
costs for such services rendered by other persons or entities of similar skill,
competence and experience; (g) costs of Landlord's general overhead and general
administrative expenses which would not be chargeable to operating expenses of
the Building under generally accepted accounting principles; (h) all items and
services for which Tenant reimburses Landlord (other than Tenant's pro rata
share of operating expenses) or for which Tenant pays third persons on behalf of
Landlord; (i) any other expenses which, under generally accepted accounting
principles, would not be classified as customary maintenance or operating
expenses of the Building; and (j) any fines, penalties, legal judgments or
settlements of causes of action by or against Landlord. The annual statement of
said operating expenses shall be made available to Tenant upon Tenant's request.

         21. ACCOUNTING FOR PASS THROUGH CHARGES. Landlord shall send to Tenant,
in writing, a statement of the amount of any additional rent determined due
pursuant to Sections 18, 19 and 20 after the end of the year with respect to
which such additional rent is due. The amount of such additional rent required
to be paid pursuant to the provisions of this Lease, as well as any other sums
of money or charges required to be paid by Tenant under this Lease, whether or
not the same shall be designated "additional rent," shall nevertheless, if not
paid when due, be collectible as additional rent with the next installment of
rent thereafter falling due. Nothing herein contained shall be deemed to suspend
or delay the payment of any amount of money or charge at the time the same
becomes due and payable hereunder or otherwise limit any remedy of Landlord to
collect the same. Tenant shall pay to Landlord monthly in advance, one-twelfth
(1/12) of the estimated annualized amounts shown as Tenant's "pro rata share" of
any additional rent to be paid in anticipation of such rent due to provide for
increases in operating expenses and other expenses as specified in Sections 18,
19 or 20 hereof for the then current calendar year, and all such additional
monthly payments shall be credited in a lump sum to Tenant's rent next due to
the extent that the amount paid by Tenant exceeds the amount actually due. Any
deficiency owed by Tenant pursuant to such an accounting shall be paid by Tenant
within thirty (30) days after receipt of written demand therefor by Landlord.




                                       15
<PAGE>


         Not more than once during each Lease Year, Tenant may, at Tenant's sole
cost and expense, audit Landlord's records and all information pertaining to
operating expense charges in order to verify the accuracy of Landlord's
determination of Tenant's share of operating expenses provided that:

         (i) Tenant must give notice to Landlord of its election to undertake
         said audit within one hundred twenty (120) days after receipt of the
         statement of the actual amount of Tenant's share of operating expenses
         for the preceding calendar year from Landlord;

         (ii) Such audit will be conducted only during regular business hours of
         the office where Landlord maintains records of operating expenses and
         only after Tenant gives Landlord fourteen (14) days advance written
         notice;

         (iii) Tenant shall deliver to Landlord a copy of the results of such
         audit within fifteen (15) days of its receipt by Tenant;

         (iv) No audit shall be conducted at any time that Tenant is in default
         of any of the terms of this Lease;

         (v) No subtenant shall have any right to conduct an audit and no
         assignee shall conduct an audit for any period during which such
         assignee was not in possession of the Premises; and

         (vi) Such audit reviewed by Tenant shall not postpone or alter the
         liability and obligation of Tenant to pay any amounts due under the
         terms of this Lease.

         Within thirty (30) days after Tenant's receipt of such audit, Tenant
must give notice to Landlord of any disputed amounts and identify all items
being contested in Landlord's statement of Tenant's share of operating expenses.
If Landlord and Tenant cannot agree upon any such item as to which Tenant shall
have given such notice, the dispute shall be resolved by an audit by a major
accounting firm mutually acceptable to Landlord and Tenant and notwithstanding
anything contained herein to the contrary, the cost of said audit shall be paid
by the non-prevailing party; provided, however, Tenant will not be considered
the "prevailing party" for purposes of this paragraph unless the accounting
firm's audit reveals an overcharge by Landlord in excess of five percent (5%) of
Tenant's share of operating expenses for the particular calendar year in
question.

         22. LANDLORD LIABILITY. Tenant agrees that Landlord shall not be liable
for injury to Tenant's business or any loss of income therefrom or for any
damage to any goods, wares, merchandise, or other property of Tenant, or
Tenant's contractors, agents, employees, invitees, customers or any other person
in or about the Premises, unless such damage or loss is solely caused by
Landlord, its agents, employees or representatives, nor shall Landlord be liable
for injury to the person of Tenant or to Tenant's contractors, agents,
employees, invitees or customers whether such damage or injury is caused by or
results from fire, steam, electricity,


                                       16
<PAGE>


gas, water or rain, or from the breakage, leakage, obstruction or other defects
of pipes, sprinklers, wires, appliances, plumbing, air conditioning or lighting
fixtures or from any other cause, whether said damage or injury results from
conditions arising upon the Premises or upon other portions of the Building of
which the Premises are a part, or from other sources or places, regardless of
whether the cause of such damage or injury or means of repairing the same is
inaccessible to Tenant except to the extent of the negligence or willful
misconduct of Landlord, its agents or employees. Landlord shall not be liable
for any loss or damages arising from any act or neglect of any other tenant. The
term "Landlord" as used in this Lease so far as covenants or obligations on the
part of Landlord are concerned shall be limited to mean and include only the
owner or owners of the Premises and Building at the time in question, and in the
event of any transfers or conveyances, the then grantor shall be automatically
freed and released from and after the date of such transfer or conveyance of all
liability as respects the performance of any covenant or obligation on the part
of Landlord contained in this Lease on the part of Landlord shall be binding on
Landlord, its successors and assigns only during and in respect to their
respective successive periods of ownership. Notwithstanding any other provision
contained herein to the contrary, in the event of a breach hereof by Landlord or
the failure of Landlord to perform any of its obligations hereunder, Landlord
shall have no personal liability therefor, but Tenant shall look solely to
Landlord's interest in the Premises for satisfaction of any claim or loss.

         23. CARE OF PREMISES. Tenant shall at all times keep the Premises and
adjoining areas and appurtenances (subject to its reasonable control) in a clean
and neat condition. Tenant covenants and agrees that Tenant, for itself, its
employees, representatives and visitors, shall:

         (a) Prohibit anything within Tenant's control which shall endanger or
cause injury to any person or property.

         (b) Prohibit any excessive loads within the Premises or any part of the
common areas, including parking areas.

         (c) Prohibit any disturbing or offensive odors, fumes, gases, smoke,
dust, steam vapors, noise or vibrations.

         (d) Keep the entryways, sidewalk and delivery and service areas clean
and free from Tenant's rubbish.

         (e) Keep the interior free of vermin. Landlord acknowledges that
poultry kept on the Premises in conjunction with Tenant's permitted use shall
not be deemed vermin.

         (f) Prohibit the use of sinks, toilets or urinals for any purpose
except that for which they are designated and installed.




                                       17
<PAGE>


         (g) Store all trash and garbage inside the Premises and provide for its
prompt and regular removal for disposal outside the Building and common areas.

         (h) Comply otherwise with all rules and regulations of Landlord,
including those Rules and Regulations set forth in Exhibit C.

         24. QUIET ENJOYMENT. Upon Tenant's paying the rent and other sums
herein reserved and its performing the covenants and agreements hereof, Tenant
shall peaceably and quietly have, hold and enjoy the Premises, and all rights,
privileges, easements and appurtenances in any way appertaining thereto, during
the Term.

         25. SURRENDER; HOLDING OVER. Tenant will vacate and deliver up the
Premises and all improvements, additions and alterations thereto, except and
only to the extent Landlord requests removal of such improvements, additions and
alterations pursuant to Section 13 (except Tenant signs, equipment and trade
fixtures installed by Tenant at its expense which may be removed by Tenant), at
the expiration or termination of this Lease, in a good, clean and tenantable
condition as the same were at the beginning of Tenant's occupancy, excepting
reasonable wear and tear (but not any extraordinary or unusual wear and tear due
to Tenant's use of the Premises), damage by fire and other casualty or
appropriation by eminent domain. Tenant expressly agrees to perform and complete
any and all of its repair or maintenance obligations specified under Section 9
prior to its vacating the Premises. Tenant may remove its trade fixtures and
equipment within five (5) days after the expiration or sooner termination of
this Lease, provided (a) Tenant is not in default hereunder; (b) removal of
Tenant item can be accomplished without major damage to the Premises; and (c)
Tenant immediately repairs (or reimburses Landlord for the cost of repairing any
resulting damage or defacement). Otherwise, all such items shall become
Landlord's property. Upon its surrender of the Premises, Tenant agrees to
provide that all entrance and exit doors are repaired and in good order, all
lighting and ballast are repaired and in good working order and all lights are
replaced, as necessary and burning, in addition to any other Tenant obligation
in connection with the condition of the Premises upon surrender.

         Tenant shall not acquire any right or interest in the Premises by
remaining in possession after the expiration or sooner termination of this Lease
without Landlord's consent. During any such period of holding over without
Landlord's consent, Tenant shall be a tenant-at-sufferance only, occupying the
Premises without the consent of Landlord, but nevertheless subject to and bound
by all terms and conditions of this Lease except those as to term hereof and
except that during such holdover tenancy, Tenant shall pay to Landlord (a) rent
at the rate equal to One Hundred Fifty Percent (150%) of the rate of rent then
existing at the end of this Lease, and (b) Tenant's pro rata share of any and
all operating expenses and all other additional rent payable hereunder.

         26. ASSIGNMENT AND SUBLEASING. Tenant may not assign, transfer,
mortgage or encumber this Lease, or sublease the Premises, in whole or in part,
without first obtaining the prior written consent of Landlord, which, provided
there is no change in the use


                                       18
<PAGE>


of the Premises, shall not be unreasonably withheld. Any assignment or sublease
to which Landlord may consent (one consent not being any basis to contend that
Landlord should consent to a further change) shall not relieve Tenant of any of
its obligations hereunder. The withdrawal or change, whether voluntary,
involuntary or by operation of law, of persons or entities owning a controlling
interest in Tenant, or the sale of Tenant's business, shall be deemed a
voluntary assignment of this Lease and subject to the provisions of this Section
26. Acceptance of rent by Landlord after any non-permitted transfer or
assignment shall not constitute approval thereof by Landlord.

         Notwithstanding anything in this Section to the contrary, Tenant may,
without Landlord's consent, assign, transfer, or sublet its leasehold interest
to a corporation, partnership, limited liability company, or other entity more
than fifty percent (50%) of the ownership of which is owned by Tenant, or to a
corporation, partnership, limited liability company, or other entity, which owns
more than fifty percent (50%) of the ownership interest in Tenant or to an
entity purchasing all or substantially all of the assets of Tenant. In the event
of any assignment, sublease or other transfer of this Lease or all or any
portion of the Premises, Tenant shall remain fully responsible and directly
liable for the payment of all rent payable pursuant to this Lease and for
compliance with all of Tenant's other obligations hereunder.

         Landlord may at any time during the Term assign its interest in this
Lease without the consent of Tenant. Landlord shall promptly notify Tenant in
writing of the identity and address of the assignee and Landlord shall cause the
assignee to notify Tenant in writing of the address for payment of rent.

         Except as otherwise expressly permitted in this Lease, in no event
shall this Lease be assignable by operation of any law, and Tenant's rights
hereunder may not become, and shall not be listed by Tenant as an asset under
any bankruptcy, insolvency or reorganization proceedings. Tenant is not, may not
become, and shall never represent itself to be an agent of Landlord, and Tenant
expressly recognizes that Landlord's title is paramount, and that it can do
nothing to affect or impair Landlord's title. If this Lease shall be assigned or
the Premises or any portion thereof sublet by Tenant at a rental that exceeds
the rental to be paid to Landlord hereunder attributable to the Premises or that
portion thereof so assigned or sublet, as the case may be, then and in such an
event, any such excess rent shall be paid over to Landlord by Tenant as
additional rent hereunder. Tenant agrees to reimburse Landlord all reasonable
out of pocket costs associated with Tenant's efforts to sublease or assign all
or part of the Premises including, but not limited to, legal fees, management
charges, construction management, engineering, architectural fees etc.

         27. SUBORDINATION; ATTORNMENT. Tenant agrees that this Lease will
either be subordinate or superior to any mortgage or other security instrument
heretofore or hereafter executed by Landlord covering the Premises, depending on
the requirements of such mortgagee. On request, Tenant will execute such
agreements making this Lease superior or subordinate as Landlord's mortgagee may
request, and will agree to attorn to said mortgagee providing the mortgagee
agrees not to disturb Tenant's possession hereunder so long as Tenant is in


                                       19
<PAGE>


compliance with this Lease. Landlord consents to Tenant's execution of
Landlord's mortgagee's subordination, attornment and non-disturbance agreement
(the "SNDA"), and to be bound by the provisions thereof. Further Tenant agrees
to execute within ten (10) days of request therefor, and as often as requested,
estoppel certificates setting forth the facts with respect to date of occupancy,
termination date of this Lease, the amount of rent due and date to which rent is
paid, whether or not it has any defenses or offsets to the enforcement of the
Lease or knowledge of any default or breach by Landlord, and that this Lease is
in full force and effect except as to any modifications or amendments, copies of
which Tenant shall attach to such estoppel certificate. Tenant agrees to attorn
to any successor of Landlord. Notwithstanding the foregoing, the subordination
of Tenant's interest in this Lease and the Premises shall be subject to the
execution by Landlord's mortgagee of an SNDA in a commercially reasonable form.

         28. DEFAULT. If Tenant: (a) fails to pay all rent as provided in this
Lease when due; (b) breaches any other agreement or obligation herein set forth;
(c) files (or has filed against it) any petition or action for relief under any
creditor's law (including bankruptcy, reorganizations, or similar actions),
either in state or federal court and in the case of an involuntary bankruptcy
filing, the petition is not dismissed within ninety (90) days after the filing
of same; or (d) becomes insolvent, makes any transfer in fraud of creditors, has
a receiver appointed for its assets, or makes an assignment for benefit of
creditors, then in addition to any other lawful right or remedy which it may
have, Landlord, subject to its duty to mitigate damages, may do the following:
(A) declare the rent for the balance of the Term immediately due and payable,
and collect the same less all sums received from any reletting of the Premises
or in the event the Premises is not relet, the present value of the then fair
rental value of the Premises for the remainder of the term based upon a discount
rate of ten percent (10%) per annum, by distress or otherwise; (B) terminate
this Lease; or (C) repossess the Premises, and with or without terminating,
relet the same at such amount as Landlord deems reasonable, and if the amount is
less than Tenant's rent, Tenant shall immediately pay the difference on demand
to Landlord, but if in excess of Tenant's rent, the entire amount shall belong
to Landlord free of any claim of Tenant thereto. All expenses of Landlord in
repairing, restoring or altering the Premises or reletting, together with
leasing fees, all other expenses in seeking and obtaining a new tenant, the
unamortized portion of Landlord's upfit costs incurred in connection with this
Lease and other damages and costs, shall be charged to and be a liability of
Tenant. Landlord's reasonable attorneys fees actually incurred at standard rates
in pursuing any of the foregoing remedies, or in collecting any rents due by
Tenant hereunder, shall be paid by Tenant, which fees as to rents collected
shall be the actual amount of such fees and expenses as may be allowed by law.
All rights and remedies of Landlord are cumulative, and the exercise of any one
shall not be an election excluding Landlord at any other time from exercising a
different or inconsistent remedy. No waiver by Landlord or any covenant or
condition shall be deemed to imply or constitute a further waiver of the same at
a later time, and acceptance of rent by Landlord even with knowledge of a
default by Tenant shall not constitute a waiver of such default. Notwithstanding
anything contained herein to the contrary, Tenant shall not be in default
hereunder with respect to the payment of any rental or other sum of money
payable hereunder until Landlord shall have given Tenant written notice of such
failure and such failure shall have continued for three (3) business days after
Tenant's receipt of such notice; provided,



                                       20
<PAGE>



however, Tenant shall not be entitled to more than two (2) such notices per
calendar year. In the case of Tenant's breach of any other non-monetary
agreement or obligation in this Lease, Tenant shall not be in default hereunder
with respect to same until Landlord shall have given Tenant written notice of
such breach and Tenant's failure shall have continued for a period of thirty
(30) days after receipt of such notice; provided, however, if such breach is not
capable of being cured within said thirty (30) day period, it shall only be
deemed a default if Tenant shall have failed to commence such cure within said
thirty (30) day period or once such cure has commenced, Tenant shall have failed
to prosecute such cure to completion within a reasonable period of time
thereafter.

         29. ATTORNEY'S FEES. If either party places in the hands of an attorney
the enforcement of this Lease or any part thereof, for the collection of any
rent due or to become due hereunder, or recovery of the possession of the
Premises, or files suit upon the same, the non-prevailing (or defaulting) party
shall pay the other party's reasonable attorneys' fees and court costs.

         30. INSPECTION. Tenant agrees that Landlord, its agents and other
representatives, shall have the right to enter into, and upon, the Premises, or
any part thereof, at all reasonable times during business hours upon prior
reasonable notice (except to the extent circumstances render such notice
impractical) for the purposes of inspecting or showing the same. Tenant further
agrees that Landlord may enter the Premises at all reasonable times during
business hours to post "For Rent" signs during the last six (6) months of the
Term, which signs may not be removed by Tenant. In conjunction with such
inspection, Landlord agrees to use reasonable efforts to not materially
interfere with Tenant's use and occupancy of the Premises and shall observe such
reasonable requirements as Tenant may impose (e.g. wearing sterile clothing and
booties for entry into "clean rooms") to protect Tenant's work in process and
proprietary information.

         31. CONDEMNATION. If the Premises are totally taken by condemnation,
this Lease shall terminate on the date of taking. If only a portion of the
Premises is taken by condemnation and Tenant can continue use of the remainder
of the Premises for the normal conduct of its business, then the Lease will not
terminate, but rent shall abate in a just and proportionate amount to the loss
of use occasioned by the taking. Tenant shall have no right or claim to any part
of any award made to or received by Landlord for any taking and no right or
claim for any alleged value of the unexpired portion of this Lease; provided,
however, that Tenant shall not be prevented from making a claim against the
condemning party (but not against Landlord) for any moving expenses, loss of
profits, or taking of Tenant's personal property (other than its leasehold
interest) to which Tenant may be entitled.

         32. RIGHT TO RELOCATE. At any time prior to Tenant's delivery of a
building permit relative to the construction of the Tenant Improvements to
Landlord, Landlord may, at its option, substitute for the Premises other space
(hereafter called "Substitute Premises") within the Building or within another
building located in the business park as may be generally shown on Exhibit A-2
before the commencement date or at any time during the Term or any extension


                                       21
<PAGE>


of this Lease. Insofar as reasonably possible and to the extent available, the
Substitute Premises shall have square footage comparable to that of the
Premises. Landlord shall give Tenant at least thirty (30) days written notice of
its intention to relocate Tenant to the Substitute Premises. This notice will be
accompanied by a floor plan of the Substitute Premises. After such notice,
Tenant shall have ten (10) days within which to agree with Landlord on the
proposed new space and unless such agreement is reached within such period of
time, this Lease shall terminate at the end of the thirty (30) day period
following the aforesaid notice. Landlord agrees to construct or alter, at its
own expense, the Substitute Premises as expeditiously as possible so that they
are in substantially the same condition that the Premises were in immediately
prior to the relocation. Landlord shall have the right to reuse the fixtures,
improvements, and alterations used in the Premises. Tenant agrees to occupy the
Substitute Premises as soon as Landlord's work is substantially completed.
Landlord shall credit Tenant with one month's rent then due as a moving
allowance. Except as provided herein, Tenant agrees that all of the obligations
of this Lease, including the payment of rent, will continue despite Tenant's
relocation of the Substitute Premises. Upon substantial completion of the
Substitute Premises, this Lease will apply to the Substitute Premises as if the
Substitute Premises had been the space originally described in this Lease.
Landlord shall use all reasonable efforts to minimize any period when the
Premises shall be closed to the public as a result of relocation. Tenant's rent
shall abate from the date the Premises are closed until the date the Substitute
Premises are open for business. Tenant agrees to use all reasonable efforts to
open for business in the Substitute Premises as quickly as is reasonably
possible under the circumstances. Except as provided above, Landlord shall not
be liable or responsible in any way for damages or injuries suffered by Tenant
pursuant to the relocation in accordance with this provision including, but not
limited to, loss of goodwill, business, or profits. Within ten (10) days of
Tenant's occupancy of the Substitute Premises, Tenant agrees to execute an
endorsement to this Lease confirming essential terms concerning the Substitute
Premises, including, without limitation, rental; a Premises description;
Tenant's proportionate share, etc.

         33. SECURITY DEPOSIT. Subject to the terms of the Lease Addendum, on or
before that date which is thirty (30) days prior to the date of expiry of the
Letter of Credit (as defined in the Lease Addendum), Tenant shall deposit an
amount equal to the then-current amount of one (1) month's Minimum Rent with
Landlord which sum Landlord shall retain as security for the performance by
Tenant of each of its obligations hereunder. If Tenant fails at any time to
perform its obligations, Landlord may at its option apply said deposit, or so
much thereof as is required, to cure Tenant's default. If prior to the
expiration or termination of this Lease Landlord depletes said deposit in whole
or in part, Tenant shall immediately restore the amount so used by Landlord.
This deposit shall not bear interest, and unless Landlord uses the same to cure
a default of Tenant, or to restore the Premises to the condition that Tenant is
required to leave them at the conclusion of the Term, Landlord shall within
thirty (30) days of the termination or expiration of the Lease refund to Tenant
so much of the deposit as remains.

         34. NOTICES. Any notices which Landlord or Tenant is required or
desires to give the other shall be deemed sufficiently given or rendered if, in
writing, is delivered personally or sent by regular mail, or if an event of
default is claimed, then either delivered personally or


                                       22
<PAGE>


sent by certified or registered mail, postage prepaid, return receipt requested
to the address listed below. Any notice given herein shall be deemed delivered
when the return receipt therefore is signed, or refusal to accept the mailing by
the addressee is noted thereon by the postal authorities.

                  LANDLORD:         Petula Associates, Ltd.
                                    Commercial Real Estate Equities
                                    711 High Street
                                    Des Moines, IA 50392
                                    Attention: Bruce K. Bruene


                  With a copy to:   TriProperties
                                    Yorkshire Property Manager
                                    1009 Slater Road, Suite 110
                                    Durham, NC 27703
                                    Attention: David M. Adams

                  TENANT:           Embrex, Inc.
                                    1035 Swabia Court
                                    Durham, NC 27703
                                    Attention:  Chief Financial Officer

         35.      HAZARDOUS MATERIALS; ENVIRONMENTAL COMPLIANCE.

         A. Tenant's Responsibility. Tenant shall not (either with or without
negligence) cause or permit the escape, disposal or release of any amount of
biologically active or other hazardous substances, or materials in excess of any
applicable legal standards (collectively hereinafter referred to as "Hazardous
Substances"). Tenant shall not allow the storage or use of said Hazardous
Substances in any manner prohibited by law or otherwise inconsistent with
commercially reasonable standards for the storage and use of such Hazardous
Substances comparable to other first class flex-space buildings used for or
containing laboratories using Hazardous Substances, nor allow to be brought into
the Building or the business park as generally shown in Exhibit A-3 any such
Hazardous Substances except to use in the ordinary course of Tenant's business.
Prior to its occupancy of the Premises, Tenant shall provide Landlord with a
list of any Hazardous Substances which it plans to introduce to the Premises and
thereafter, on each anniversary of the Commencement Date, Tenant shall update
said list and identify which Hazardous Substances have been used within the
Premises and which Hazardous Substances may be used within the Premises in the
future. In addition, prior to Tenant's occupancy of the Premises, Tenant agrees
to submit a plan detailing the method of disposal, storage and treatment of such
Hazardous Substances to Landlord for Landlord's approval. Tenant covenants and
agrees that the Premises will, at all times during its use or occupancy thereof,
be kept and maintained so as to comply with all now existing or hereafter
enacted or issued statutes, laws, rules, ordinances, orders, permits, and
regulations of all state, federal,


                                       23
<PAGE>


local, and other governmental and regulatory authorities, agencies, and bodies
applicable to the Premises, pertaining to environmental matters, or regulating,
prohibiting or otherwise having to do with asbestos and all other toxic,
radioactive, or hazardous wastes or materials including, but not limited to, the
Federal Clean Air Act, the Federal Water Pollution Control Act, and the
Comprehensive Environmental Response, Compensation, and Liability Act of 1980,
as from time to time amended (all hereinbefore and hereinafter collectively
called the "Environmental Laws" or "Laws"). Landlord warrants and represents to
Tenant that the construction of the shell of the Building by Landlord and its
contractor shall comply in all material respects with applicable laws.
Notwithstanding the foregoing, any noncompliance with such applicable laws shall
not have a materially adverse impact on Tenant's use or occupancy of the
Premises or the health or safety of Tenant, its employees or invitees.

         B. Tenant's Liability. In addition to the indemnifications contained in
Section 15 hereof, Tenant shall hold Landlord, its agents, representatives,
successors or assigns, free, harmless, and indemnified from any penalty, fine,
claim, demand, liability, cost, or charge whatsoever which Landlord or others as
aforesaid shall incur, or would otherwise incur, by reason of Tenant's failure
to comply with this Section 35; including, but not limited to: (i) the cost of
bringing the Premises into compliance with all Laws; (ii) the reasonable cost of
all appropriate tests and examinations of the Premises to confirm that the
Premises have been brought into compliance with all Laws; and (iii) the
reasonable fees and expenses of Landlord's attorneys, engineers, and consultants
incurred by Landlord in enforcing and confirming compliance with Section 35.

         C. Property. For the purposes of this Section 35, the Premises shall
include the Premises identified in Section 1 above, together with the real
estate covered within the Site Plan, Exhibit A-3, and all structures and
improvements thereon; all personal property used by Tenant in connection with
the Premises (including that owned by Tenant); and the soil, ground water, and
surface water of the Premises, as this term is defined in this Subsection 35(C).

         D. Inspections by Landlord. Landlord and its engineers, technicians,
and consultants (collectively the "Auditors") may, from time to time as Landlord
deems appropriate during Tenant's business hours and upon prior reasonable
notice (except to the extent emergency circumstances render such notice
impractical), conduct periodic tests and examinations ("Audits") of the Premises
to confirm and monitor Tenant's compliance with this Section 35 and shall
observe such reasonable requirements as Tenant may impose (e.g. wearing sterile
clothing and booties for entry into "clean rooms") to protect Tenant's work in
process and proprietary information. Such Audits shall be conducted in such
manner as to minimize the interference with Tenant's permitted activities on the
Premises; however, in all cases, the Audits shall be of such nature and scope as
shall be reasonably required by then existing technology to confirm Tenant's
compliance with this Section 35. Tenant shall fully cooperate with Landlord and
its Auditors in the conduct of such Audits. The cost of such Audits shall be
paid by Landlord unless an Audit shall disclose a material failure of Tenant to
comply with this Section 35, in which case the cost of such Audit, and the cost
of all subsequent Audits made during the Term and within thirty (30) days
thereafter (not to exceed two (2) such Audits per calendar year) shall


                                       24
<PAGE>


be paid for by Tenant within thirty (30) days after receipt of written demand
therefor, together with such supporting documentation as Tenant may reasonably
request.

         E. Landlord's Liability. Provided, however, the foregoing covenants and
undertakings of Tenant contained in this Section 35 shall not apply to any
condition or matter constituting a violation of any Law: (i) which existed prior
to the commencement of Tenant's use or occupancy of the Premises and was not
caused, in whole or in part, by Tenant or Tenant's agents, employees, officers,
partners, contractors, representatives or invitees; or (ii) to the extent such
violation is solely caused by the acts or neglects of Landlord, its employees,
agents or representatives.

         F. Tenant's Liability After Termination of Lease. The covenants
contained in this Section 35 shall survive the expiration or termination of this
Lease, and shall continue for so long as Landlord and its successors and assigns
may be subject to any expense, liability, charge, penalty, or obligation against
which Tenant has agreed to indemnify Landlord under this Section 35.

         36. BROKER'S COMMISSIONS. Tenant represents and warrants that it has
not had dealings with any real estate broker, finder or other person, with
respect to this Lease in any manner, except Corporate Realty Advisors, the
address of which is 4000 WestChase Boulevard, Suite 390, Raleigh, North Carolina
27607 and Tri-Properties, Inc. whose address is 1009 Slater Road, Suite 110,
Durham, North Carolina 27703. Landlord shall pay any commissions or fees that
are payable to the above-named broker or finder with respect to this Lease.
Tenant shall indemnify and hold Landlord harmless from any and all damages
resulting from any claims that may be asserted against Landlord by any other
broker, finder or other person, with whom Tenant has or purportedly has dealt.
The provisions of this Section 36 shall survive the termination or expiration of
this Lease.

         37. MISCELLANEOUS. Headings of sections are for convenience only and
shall not be considered in construing the meaning of the contents of such
sections. The invalidity of any portion of this Lease shall not have any effect
on the balance hereof. Should either party institute any legal proceedings
against the other for breach of any provision herein contained, and prevail in
such action, the other party shall in addition be liable for the costs and
expenses of the party initiating the action, including its reasonable attorney's
fees. This Lease shall be binding upon the respective parties hereto and upon
their heirs, executors, successors and assigns. This Lease supersedes and
cancels all prior negotiations between the parties, and changes shall be in
writing signed by the party affected by such change. Landlord reserves the right
to make and change from time to time rules it deems appropriate for the common
use and benefit of all tenants, with which rules Tenant shall comply, provided
such rules are reasonable and nondiscriminatory. Any agreed to measurement of
space shall be done in accordance with Building Owners and Managers Association
("BOMA") standards used to determine "rentable" square feet for warehouse/flex
space. Landlord may sell the Premises subject to the terms of this Lease without
affecting the obligations of Tenant hereunder. This Lease may not be recorded
without Landlord's prior written consent; provided, however, upon the request of
either


                                       25
<PAGE>


party, the other agrees to execute and deliver a statutory form of memorandum of
lease and the party requesting such memorandum shall prepare the memorandum and
be responsible for any applicable recording fees with respect to same. The
singular shall include the plural, and the masculine, feminine or neuter
includes the other. Each of Landlord and Tenant respectively represents to the
other that each has the lawful authority to enter into this Lease and by signing
it in their name as set forth below, to be legally bound in accordance with its
terms and conditions. No failure by Landlord or Tenant to insist upon the strict
performance or observance of any term or condition of this Lease, or to seek
redress or to exercise any right or remedy after any such failure or breach
hereof, shall constitute a waiver of any such term, condition, obligation, right
or remedy, or any such failure or breach then or thereafter occurring. No term,
condition or obligation of this Lease to be performed or observed by Tenant or
Landlord shall be waived, altered or modified except by a writing executed by
Landlord or Tenant, as the case may be. No waiver of any failure, breach or
default hereof shall affect or alter this Lease, but each and every term,
condition and obligation of this Lease shall continue in full force and effect
with respect to any other failure, breach or default. This Lease, and the rights
and obligations of each of Landlord and Tenant hereunder shall be governed by
and construed in accordance with the laws of the State of North Carolina.
Landlord warrants and represents to Tenant that Landlord is seized of fee
simple, marketable title to the land on which the Building and the Premises will
stand.

         38. SPECIAL CONDITIONS, EXHIBITS AND ADDENDA. The following special
conditions, if any, shall apply, and where in conflict with earlier provisions
in this Lease shall control. If any Lease Exhibits or Addenda are noted below,
such exhibits and addenda are incorporated herein and made a part of this Lease.
If there are no special conditions, exhibits or addenda, the word NONE shall be
written in the blank below.

         Lease Addendum:           Letter of Credit
         Exhibit A-1:              Floor Plan
         Exhibit A-2:              Legal Description of Real Property
         Exhibit A-3:              Building Site Plan
         Exhibit A-4:              Business Park Site Plan
         Exhibit B:                Space Plan - Tenant Improvements,
                                            Plans and Specifications
         Exhibit B-1:              Landlord's Work
         Exhibit C:                Rules and Regulations
         Exhibit D:                Contract Standards for HVAC, Inspection
                                            Maintenance and Repair
         Exhibit E:                [Intentionally Deleted]
         Exhibit F:                Permitted Signage
         Exhibit G:                Extension of Term



                                       26
<PAGE>



         IN WITNESS WHEREOF, Landlord and Tenant have executed this Lease by
hand and under seal affixed hereto in duplicate originals, all as of the day and
year first above written.


                                            LANDLORD:

                                            Petula Associates, Ltd.,
                                            an Iowa corporation
ATTEST:

/s/ Timothy E. Minton                       By:  /s/ Ronald B. Franklin
- ---------------------                            ----------------------
Vice President & Secretary                       Vice President

                                            By:  /s/ Scott D. Harris
[CORPORATE SEAL]                                 -----------------------
                                                 Vice President

                                            TENANT:

                                            Embrex, Inc.,
                                            a North Carolina corporation
ATTEST:

/s/ Don T. Seaquist                         By:  /s/ Randall L. Marcuson
- -------------------                              -----------------------
Corporate Secretary                                  CEO & President

[CORPORATE SEAL]



                                       27
<PAGE>


STATE OF IOWA

COUNTY OF POLK

         I, Susan Wieland, a Notary Public in and for said County and State, do
certify that Timothy E. Minton personally came before me this day and
acknowledged that he is Vice President & Secretary of Petula Associates, Ltd.,
an Iowa corporation, and that by authority duly given and as the act of the
corporation, the foregoing instrument was signed in its name by its Vice
President, sealed with its corporate seal, and attested by him as its Vice
President and Secretary.

         WITNESS my hand and notarial seal this 13th day of October, 1997.

                                                           /s/ Susan Wieland
                                                           -----------------
                                                           Notary Public
My Commission Expires:

July 28, 2000

(NOTARIAL SEAL OR STAMP)


STATE OF NORTH CAROLINA

COUNTY OF DURHAM

         I, Colleen S. Loree, a Notary Public in and for said County and State,
do certify that Don T. Seaquist and Randall L. Marcuson personally came before
me this day and acknowledged that he/she is __________ Secretary of Embrex,
Inc., a North Carolina corporation, and that by authority duly given and as the
act of the corporation, the foregoing instrument was signed in its name by its
_________ President, sealed with its corporate seal, and attested by him/herself
as its _____ Secretary.

         WITNESS my hand and notarial seal this 5th day of September, 1997.

                                                        /s/ Colleen S. Loree
                                                        --------------------
                                                            Notary Public
My Commission Expires:

April 15, 2001

(NOTARIAL SEAL OR STAMP)



                                       28
<PAGE>

                                   EXHIBIT A-1

                                   FLOOR PLAN

                        [map of floor plan appears here]


                                       29
<PAGE>


                                   EXHIBIT A-2

                       LEGAL DESCRIPTION OF REAL PROPERTY

Being all of Lot S20 of Imperial Center located in Triangle Township, Durham
County, North Carolina, containing 15.367 acres, as shown on that plat entitled
"Lot S20 - Imperial Center" dated May 4, 1988, prepared by Kenneth Close, Inc.
And recorded in Plat Book, Page 166, Durham County Registry.



                                       30
<PAGE>


                                   EXHIBIT A-3

                               BUILDING SITE PLAN

                    [map of building site plan appears here]



                                       31
<PAGE>


                                   EXHIBIT A-4

                             BUSINESS PARK SITE PLAN

                    [map of business park plan appears here]



                                       32
<PAGE>


                                    EXHIBIT B

                                   SPACE PLANS


         Final plans shall be attached.



                                       33
<PAGE>



                                   EXHIBIT B-1

                                 LANDLORD'S WORK


A.       Structural

         1. Steel framing, bar joist and metal deck
         2. Exterior load bearing walls (masonry or stud) and demising wall 3.
            Metal stairs


B.       Exterior Non-Structural

         1. Windows, frames, glass and blinds
         2. Roofing - membrane, drains and ballast
         3. Utilities stubbed to the Building - electrical, water, sewer


C.       Interior Non-Structural

         1. Fire protection - sprinkler systems, riser
         2. Telephone/Telecommunications, conduit to the equipment room only
         3. Utilities - water, conduit provided; new tap and line by Tenant
         4. Main sewer line and cleanouts



                                       34
<PAGE>


                                    EXHIBIT C

                              RULES AND REGULATIONS


         The following rules and regulations have been adopted by Landlord for
the care, protection and benefit of the Building and for the general comfort and
welfare of the tenants. These Rules and Regulations shall remain in full force
and effect until Tenant is notified in writing by Landlord of any changes and
amendments. To the extent any of the Rules and Regulations set forth herein are
inconsistent with the provisions of the Lease, the terms and conditions of the
Lease shall prevail.

         1. The sidewalks, entrances, halls, passages, elevators, and stairways
of the common areas shall not be obstructed or used by Tenant for any other
purpose than for ingress and egress. All loading and unloading of goods,
furniture, fixtures, equipment and supplies shall be done only in areas and
through entrances designated for such purposes.

         2. Toilet rooms and other plumbing facilities shall not be used for any
purpose other than those for which they are constructed and no foreign substance
of any kind shall be disposed of therein. All repairs required due to breakage,
stoppage or damage resulting from a violation of this provision shall be at
Tenant's sole expense.

         3. Tenant shall not do anything in the Premises, or bring or keep
anything therein, which shall in any way conflict with any law, ordinance, rule
or regulation affecting the occupancy and use of the Premises, which are or may
hereafter be enacted or promulgated by any public authority or by the Board of
Fire Underwriters.

         4. Tenant shall at all times maintain suitable fire extinguishers on
the Premises in compliance with any applicable law or ordinance for use in case
of local fires, including electrical fires.

         5. Tenant shall keep the Premises heated at a temperature sufficiently
high to prevent freezing of water in pipes and fixtures.

         6. Except for the infrequent overnight parking of unloaded, mid-size
delivery vans and trucks required in the ordinary course of Tenant's business
(such overnight parking not to exceed twelve (12) nights per year), trucks shall
not be allowed to remain overnight in the common area whether loaded, unloaded
or otherwise, without Landlord's prior written consent.

         7. All garbage and refuse shall be placed for collection in containers
specified by Landlord outside the Premises or Building. Tenant shall pay the
cost of removal of any of Tenant's refuse or rubbish.




                                       35
<PAGE>


         8. Tenant shall, at Tenant's expense, provide for regular pest
extermination to the Premises and shall provide Landlord with a copy of such
extermination contract.

         9. In order to insure proper use and care of the Premises, neither
Tenant nor any agent or employee of Tenant shall:

                  (a)      Allow any furniture, packages or articles of any kind
                           to remain in corridors outside the Premises except
                           for short periods incidental to moving same in or out
                           of Building or to cleaning or rearranging occupancy
                           of leased space.

                  (b)      Mark or defile elevators, toilet rooms, walls,
                           windows doors or any part of the Building.

                  (c)      Except for "seeing-eye" dogs, keep animals or birds
                           on the Premises.

                  (d)      Deposit waste paper, dirt or other substances in
                           corridors, stairways, elevators, toilets, restrooms,
                           or any other part of the Building not leased by
                           Tenant.

                  (e)      Except for pictures, wall hangings and other
                           customary office decorations and except for items
                           which would not cause permanent damage to the
                           structural elements of the Building, fasten any
                           article, drill holes, drive nails or screws into
                           walls, floors, doors, or partitions, or otherwise mar
                           or deface them by paint, papers or otherwise, without
                           Landlord's prior written consent.

                  (f)      Operate any machinery within the Building without
                           Landlord's prior written consent except for: (i)
                           customary office equipment, such as computers,
                           dictaphones, calculators, electric typewriters, and
                           the like and (ii) special equipment or machinery used
                           in the ordinary course of the operations of Tenant's
                           business, provided such special equipment or
                           machinery shall not cause permanent damage to the
                           structural elements of the Premises or the Building
                           nor interfere with the other tenants of the Building.

                  (g)      Leave Premises unoccupied without: (i) locking all
                           exterior doors to the Premises, or (ii) extinguishing
                           lights and turning off all water outlets except as
                           required in the ordinary course of Tenant's
                           operations in the Premises.

                  (h)      Burn any trash, refuse, debris or garbage of any kind
                           in or about the Premises or Building.



                                       36
<PAGE>


                  (i)      Attach awnings, air-conditioning units or other
                           fixtures to the outside walls or window sills, or
                           otherwise affix such so as to project from the
                           Premises or Building without Landlord's prior written
                           consent.

                  (j)      Install additional locks or bolts of any kind on any
                           doors or windows of the Premises without Landlord's
                           prior written consent. On the termination of Tenant's
                           tenancy, Tenant shall deliver to Landlord all keys to
                           the Premises, either furnished to or otherwise
                           procured by Tenant.

                  (k)      Install or operate any engine, boiler, machinery, or
                           stove, or use oil or any burning fluid (other than
                           gas) for heating, warming or lighting, or use any
                           lighting other than incandescent or fluorescent
                           electric lights, on the Premises without Landlord's
                           prior written consent. All stoves permitted in the
                           Premises shall be placed and installed according to
                           city ordinances. No articles deemed extra hazardous
                           on account of fire, and no explosives, shall be
                           brought into the Premises.

                  (l)      Use loudspeakers, televisions, radios or other
                           devices in such a manner as to be heard outside the
                           Premises, or make, or permit to be made, any
                           unseeming or disturbing noises, nuisance or other
                           activity objectionable to other tenants.

                  (m)      Use the Premises for the purpose of lodging or
                           sleeping rooms, or for any immoral or illegal
                           purposes.

                  (n)      Install any aerial, antenna, satellite dish or other
                           equipment or structure on the roof or exterior walls
                           of the Premises, or on the grounds without, in each
                           instance, the prior written consent of Landlord. Any
                           installation so made without such prior written
                           consent shall be subject to removal without notice at
                           any time, at Tenant's expense.

         10. Landlord shall have the right to prohibit any advertising by Tenant
which, in its opinion, shall damage the reputation of the Building or its
desirability, and upon written notice from Landlord, Tenant shall discontinue
any such advertising.

         11. Landlord reserves the right to designate the time when and method
whereby freight, furniture, safes, goods, merchandise and other articles may be
brought into, moved or taken from the Building and the Premises leased by
Tenant, provided such designation shall not unreasonably interfere with the
normal conduct of Tenant's business in the Premises. Workmen employed by Tenants
for repairs, painting, material moving and other similar work that may be done
on the Premises must be properly insured and must perform the work in a manner
consistent with Building standards; provided, however, any workmen employed by
Tenant to work on the structure of the Building or the Building systems
(including without limitation HVAC) must be approved in writing by Landlord.



                                       37
<PAGE>

         12. Tenant will reimburse Landlord for the cost of repairing any damage
to the Premises or other parts of the Building caused by Tenant or the agents or
employees of Tenant, including replacing any glass broken.

         13. Tenant shall not install in the Premises any metal safes or permit
any concentration of excessive weight in any portion thereof without first
having obtained the written permission of Landlord.

         14. Landlord reserves the right at all times to exclude newsboys,
loiterers, vendors, solicitors and peddlers, from the Building or common area
and to require registration, satisfactory identification and credentials from
all persons seeking access to any part of the Building or common area outside of
ordinary business hours. Ordinary business hours shall mean Monday through
Friday, 8:00 a.m. to 6:00 p.m., except on legal holidays. Landlord shall
exercise its best judgment in the execution of such control but shall not be
held liable for the granting or refusal of such access. Landlord reserves the
right to exclude the general public from the Building after ordinary business
hours and on weekends and holidays. Landlord shall not unreasonably deny
Tenant's employees, contractors or invitees access to the Building or common
areas outside ordinary business hours.

         15. The attaching of wires to the outside of the Building is absolutely
prohibited, and no wires shall be run or installed in any part of the Building
without Landlord's permission and direction.

         16. Requests for services of janitors or other Building employees must
be made to Landlord. Agents or employees of Landlord shall not perform any work
or do anything outside of their regular duties unless under special instructions
from Landlord.

         17. Signs or any other Tenant identification shall be in accordance
with building standard signage. No signs of any nature shall be placed in the
windows so as to be visible from the exterior of the Building. All signs not
approved in writing by Landlord shall be subject to removal without notice.

         18. Except as otherwise set forth in the Lease, any improvements or
alterations to the Premises by Tenant shall be approved in advance by Landlord
and all such work, if approved, shall be done at Tenant's sole expense under the
supervision of Landlord.

         19. Tenant shall have a non-exclusive right to use of all driveways and
parking areas designated for Tenant and Tenant's employees, if deemed necessary
by Landlord.

         20. If additional drapes or window decorations are desired by Tenant,
they shall be approved by Landlord and installed at Tenant's expense under the
direction of Landlord. Lining on drapes visible from the exterior shall be of a
color approved by Landlord.



                                       38
<PAGE>


         21. The possession of weapons, including concealed handguns, is
strictly forbidden on the Premises and Building.

         22. Tenant shall not use nor permit the use of the common area by its
employees, agents or invitees for the purpose of displaying or selling personal
property, automobiles, equipment, furniture, fixtures, merchandise or any other
item whether owned by Tenant or its employees, agents or invitees.

         23. Landlord reserves the right to rescind, amend, alter or waive any
of the foregoing rules and regulations at any time in a reasonable and
nondiscriminatory manner, or make such other reasonable rules and regulations as
in its sole judgement it deems necessary, desirable or proper for its best
interest and for the best interests of the tenants, or as may from time to time
be necessary for the safety, care and cleanliness of the Premises, the Building
or adjacent areas, and for the preservation of good order therein. Any such
recision, amendment, alteration or waiver of any rules or regulations or
creation of any such new rules or regulations shall be effective five (5) days
after all tenants have been given written notice thereof. Landlord shall not be
responsible to any tenant for the non-observance or violation by any other
tenant of any of these rules and regulations at any time.



                                       39
<PAGE>


                                    EXHIBIT D

                           CONTRACT STANDARDS FOR HVAC
                       INSPECTION, MAINTENANCE AND REPAIR


         Pursuant to Section 9 of the Lease, Tenant is obligated to enter into
and maintain a maintenance contract for heating and air conditioning systems and
equipment at the Premises, for the Term, and any renewal or extension hereof.
The following sets forth minimum standards in connection with the services
contract so as to accomplish a preventative maintenance inspection and service
program for the HVAC systems and equipment at the Premises. At minimum, contract
services shall include four (4) scheduled inspections and routine preventative
maintenance service calls per year. The contract shall further provide that
emergency call service shall be available on a twenty-four (24) hour a day
on-call basis. The services contract shall include, without limitation, the
following types of services:

         (1) Regular preventative maintenance to heating, ventilation and air
conditioning equipment as follows:

                  A.       Compressors

                           1.       Check suction and head pressures
                           2.       Electrical amperes
                           3.       All electrical connections

                  B.       Condenser Coil

                           1.       Clean coil (if needed) and check fan
                                    condition
                           2.       Check oil level and condition
                           3.       Check for refrigerant leaks

                  C.       Air Handling Side

                           1.       Volts and amperes of motor
                           2.       Electrical connections
                           3.       Adjust belts and pulleys
                           4.       Check and lube bearings and motors
                           5.       Clean coil (if needed) and check fan
                                    condition
                           6.       Change filters
                           7.       Check for condensate leaks

                  D.       Boiler (if applicable)

                           1.       Check fire



                                       40
<PAGE>


                           2.       Pressures
                           3.       Oil and check pumps
                           4.       Burners
                           5.       Water temperature
                           6.       Safety controls

                  E.       Check out heating side of units as well as cooling
                           side.

                  F.       Check to make sure thermostats are operating
                           properly.

         (2) Emergency call service as needed (beyond routine preventative
service) due to mechanical failure of HVAC equipment.


                                       41
<PAGE>


                                    EXHIBIT E

                              CONSUMER PRICE INDEX


                             [Intentionally Deleted]


                                       42
<PAGE>



                                    EXHIBIT F

                                PERMITTED SIGNAGE


                   [drawing of proposed signage appears here]



                                       43
<PAGE>



                                    EXHIBIT G

                                EXTENSION OF TERM

         Provided no Event of Default has occurred and is continuing hereunder,
Tenant is hereby granted the option to extend the Term once for an additional
period of five (5) years (the "Extension Term") commencing upon the expiration
of the initial Term on the same terms and conditions (except as provided in this
Section) as contained in the other provisions of this Lease. This option shall
be exercised only by delivery of written notice to Landlord no later than nine
(9) months prior to the scheduled expiration date of the initial Term. The
Minimum Rent for the Premises during the five year extension term shall be as
follows:

Lease Year          Rate per             Monthly Rent         Annual Rent
                    Rentable s.f.
- --------------------------------------------------------------------------
    1                  13.00              13,827.67           165,932.00
    2                  13.52              14,380.77           172,569.28
    3                  14.06              14,955.15           179,461.84
    4                  14.62              15,550.81           186,609.68
    5                  15.21              16,178.37           194,140.44

Tenant agrees that it will continue to occupy the Premises during the Extension
Term in its "as is" condition without any further improvements thereto or
additional upfitting allowance. Tenant's occupancy of the Premises during the
Extension Term shall be subject to all other terms and conditions of this Lease,
expressly including without limitation, Tenant's obligation to pay Tenant's
proportionate share of insurance costs, taxes and operating expenses.



                                       44
<PAGE>


                                 LEASE ADDENDUM


         LETTER OF CREDIT: Tenant shall deliver to Landlord within five (5) days
after this Lease has been fully executed, an irrevocable Letter of Credit (the
"Letter of Credit") drawn on a national bank with an office in Wake or Durham
Counties of North Carolina (at which office Landlord shall be able to draw on
such letter) in the principal amount of:

         Lease Years:      1 - 4:   $275,000.00
                           5 - 7:   $175,000.00

         The Letter of Credit shall provide that if Tenant defaults under the
terms of the Lease and does not cure such default within the applicable cure
periods, if any, that Landlord may draw on the same. This Letter of Credit shall
be for a period of seven (7) years, or alternatively shall be for seven (7)
successive periods of one (1) year each with a provision that if a renewal
Letter of Credit is not delivered to Landlord within sixty (60) days of the date
of expiry on the Letter of Credit, Landlord may draw it down. After seven (7)
years, Landlord shall not require any further Letter of Credit from Tenant.

         Landlord agrees to contribute up to $2,750.00 per year for Lease Years
one (1) through four (4) and $1,750.00 per year for Lease Years five (5) through
seven (7) to be applied toward Tenant's cost of the Letter of Credit. Landlord
shall reimburse to Tenant Landlord's share of such cost of the Letter of Credit.

         After the end of the seventh Lease Year of the Term, Tenant shall not
be required to deposit any Letter of Credit or sum with Landlord to secure its
obligations under this Lease provided Tenant provides to Landlord reasonably
acceptable evidence of Tenant's creditworthiness. If, in the exercise of its
reasonable judgment, Landlord determines that a security deposit is necessary,
Tenant shall deposit with Landlord a sum equal to the then-current amount of one
month's rent thirty (30) days prior to the date of expiry of the Letter of
Credit. Landlord shall deposit this amount in a non-interest bearing account and
shall not commingle this deposit with other funds of Landlord or other tenant
deposits. Within thirty days after expiration of the Term, Landlord shall return
the security deposit to Tenant less the amount of any charges or damages Tenant
is obligated to pay Landlord hereunder or for which Tenant is liable hereunder.



                                       45
<PAGE>

                                 EXHIBIT 10.34*



                        INOVOJECT(R) EGG INJECTION SYSTEM
                         LEASE, LIMITED LICENSE, SUPPLY
                              AND SERVICE AGREEMENT

     This  Agreement  is  made as of the 1st  day of  September,  1994,  between
EMBREX, INC., a North Carolina corporation ("EMBREX"),  and Tyson Foods, Inc., a
Delaware  corporation  ("Lessee") upon the following  terms,  and supersedes the
agreement of May 4, 1993.

     1.  LEASE AND  LIMITED  LICENSE:  EMBREX  leases to  Lessee  ("the  Lease")
INOVOJECT(R)  systems and grants  Lessee a limited  sublicense  to practice U.S.
Patent  4,458,630,  "Disease Control in Avian Species by Embryonal  Vaccination"
(the  "License") for use at the  hatcheries  listed in Schedule A and Schedule B
(the "Hatcheries")  subject to the EMBREX Standard Terms and Conditions of Lease
set forth in Attachment A hereto;  provided,  however, that, in the event of any
inconsistencies  between the Standard  Terms and Conditions of Lease and express
terms of this Agreement,  the terms of this Agreement shall control. The term of
this  Agreement  shall be for the  period  commencing  September  1,  1994,  and
continuing  for each of the  Hatcheries  listed on  Schedule A until  August 31,
1998,  and for each of the  Hatcheries  listed on Schedule B until  December 31,
1998.

     2. INSTALLATION: INOVOJECT(R) systems have been installed in the Hatcheries
listed in  Schedule  A, and the  parties  agree  that  they will use their  best
efforts to install  INOVOJECT(R)  systems in the Hatcheries listed in Schedule B
on or before the Installation Dates indicated.

     3. COMPENSATION: *


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."


<PAGE>


     4. SUPPLIES:  EMBREX shall supply Lessee with standard  System  disposables
(i.e., needles, punches and tubing) at no charge (collectively, the "Supplies").

     5. SERVICE: EMBREX will provide at no cost to Lessee initial training for a
reasonable number of Lessee personnel in the proper use and routine  maintenance
of  INOVOJECT(R),  all  non-routine  service  and  reasonable  modifications  of
INOVOJECT(R) to accommodate  Lessee's specific Hatchery needs. Any other service
shall be charged to Lessee at standard EMBREX rates.

     6. PAYMENT  TERMS:  Within ten (10) days following the end of each calendar
month, Lessee shall notify EMBREX of the number of eggs which have been injected
during such prior month and shall remit the  appropriate  payment for the Lease,
License and  Supplies  used during such month.  Lessee  shall remit  payment for
other  supplies  and  services  provided  by EMBREX  within  thirty (30) days of
receipt of invoice.


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."


<PAGE>


     7. TERMINATION: *

     8.  CONFIDENTIALITY:  Each party agrees that for the term of this Agreement
they shall use their best efforts to prevent  disclosure of the financial  terms
of this  Agreement to any third party without the prior  written  consent of the
other. This commitment shall not affect,  however,  the right of either party to
announce or disclose the existence of this Agreement.

     9. DESIGNATED  CONTACT  PERSON:  Lessee agrees that during the term of this
Agreement it shall  designate to EMBREX one individual at each of the Hatcheries
where an  INOVOJECT(R)  system has been  placed  responsible  for  -coordinating
operation,  training and minor  maintenance.  Until further notice in writing to
EMBREX,  the  individual  designated at each of the  Hatcheries  shall be as set
forth in Schedule A and Schedule B.



EMBREX, INC. (Lessor)                   TYSON FOODS, INC. (Lessee)


By:  /s/ Randall L. Marcuson            By:  /s/ David S. Purtle
     ---------------------------             -------------------------------
         Randall L. Marcuson                     David S. Purtle
         President                               Senior Vice-president


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."


<PAGE>


                                   SCHEDULE A


                                        *




Acknowledged and Agreed:

TYSON FOODS, INC. (Lessee)                  EMBREX, INC. (Lessor)


By:  /s/ David S. Purtle                    By:  /s/ Kenneth P. West
     ------------------------------              -------------------------------
     David S. Purtle                             Kenneth P. West
     Sr. Vice President                          Vice President
     Date: September 1, 1994                     Date: August 31, 1994


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."


<PAGE>


                                   SCHEDULE B


                                        *




Acknowledged and Agreed:

TYSON FOODS, INC. (Lessee)                  EMBREX, INC. (Lessor)


By:   /s/ David S. Purple                   By:  /s/ Randall L. Marcuson
     -----------------------------              --------------------------------
      David S. Purtle                                Randall Marcuson
      Sr. Vice President                             President
Date: 9/1/94                                Date:    9/1/94


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."



                                 EXHIBIT 10.35*


26 March 1997

Gene Lovette
Tyson Foods, Inc.
P.O. Box 88
1600 River Road
Wilkesboro, NC 28697


Dear Mr. Lovette;

As discussed,  EMBREX INC. and TYSON FOODS, INC. wish to make certain amendments
to their Lease,  Limited License,  Supply and Service  Agreement dated September
1994 (the  "Agreement").  This Amendment is intended to document the amendments,
which are as follows

1.   The term of the Agreement shall be extended to 31 December 2004.

2.   The pricing will be: *

3.   *


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."


<PAGE>


4.   [This section left blank in original agreement.]

5.   If either party wishes to discontinue the Agreement, a written twelve month
     notice must be given.

6.   EMBREX has the right of last refusal to meet any offer being  considered by
     Tyson Foods for chick vaccination (any method).

7.   Tyson will not release Embrex pricing to its hatcheries  until the first of
     each year.

8.   *

9.   All  hatcheries  will operate under the same pricing.  Any hatchery that is
     added  or  converted  will be  priced  according  to the  date  and year of
     installation.

10.  Tyson will maintain the provisions of the Agreement in confidence except as
     (and only to the extent)  otherwise  required by  applicable  law, and even
     then only with prior notice to Embrex.

11.  Except as so amended,  the  Agreement  shall remain  unchanged  and in full
     force and effect.

Please indicate Tyson Food's  agreement to these amendments by signing below and
returning one signed copy of this letter to Embrex.


EMBREX, INC. (Lessor)              TYSON FOODS, INC. (Lessee)




By:  /s/ Brian V. Cosgriff         By:  /s/ David S. Purtle
     ---------------------------        ----------------------------------------
     Brian V. Cosgriff                  Name: David S. Purtle
     Vice-president                     Title:   Executive Vice President
                                        Operations, Warehousing & Transportation


* Selected  portions have been deleted as  confidential  pursuant to Rule 24b-2.
Complete  copies of the  entire  exhibit  have been  filed  separately  with the
Commission and marked "CONFIDENTIAL TREATMENT."



                                   EXHIBIT 21

                                  EMBREX, INC.
                                  SUBSIDIARIES

                                                              Jurisdiction of
Name                                                           Organization
- ----                                                          ---------------

Embrex Europe Limited                                         United Kingdom

Embrex Sales, Inc.                                            North Carolina



                                       50


                                   EXHIBIT 23

                         CONSENT OF INDEPENDENT AUDITORS

We consent to the inclusion in the Annual Report (Form 10-K) of Embrex,  Inc. of
our report dated  February 20, 1998 with respect to the  consolidated  financial
statements of Embrex,  Inc. and  subsidiaries  and of our report dated March 19,
1998 with respect to the financial  statements of Embrex,  Inc.  Employee  Stock
Purchase Plan.

We also consent to the incorporation by reference in the Registration  Statement
on Form S-3 (No.  333-18231) and the  Registration  Statements on Form S-8 (Nos.
33-51582,  33-63318,  333-04109)  of our report  dated  February  20,  1998 with
respect  to  the  consolidated   financial   statements  of  Embrex,   Inc.  and
subsidiaries  included  in the  Annual  Report  (Form  10-K) for the year  ended
December 31, 1997.

We also consent to the incorporation by reference in the Registration  Statement
on Form S-8 (No.  33-63318)  of our report  dated March 19, 1998 with respect to
the consolidated financial  statements of Embrex,  Inc. Employee Stock Purchase
Plan included in the Annual Report (Form 10-K) for the year ended December 31,
1997.

                                       /s/ Ernst & Young LLP

Raleigh, North Carolina
March 30, 1998



                                   EXHIBIT 24

                                POWER OF ATTORNEY

We, the  undersigned  directors and officers of EMBREX,  INC., a North  Carolina
corporation  (the  "Company"),  do hereby  constitute  and  appoint  Randall  L.
Marcuson  and  Don  T.  Seaquist  or  either  of  them,   our  true  and  lawful
attorneys-in-fact  and agents,  with full power of substitution,  to execute and
deliver  an Annual  Report on Form 10-K  pursuant  to Section 13 or 15(d) of the
Securities  Exchange Act of 1934,  as amended  (the "Act"),  with respect to the
year ended  December  31,  1997,  to be filed with the  Securities  and Exchange
Commission,  and to do any and all acts and things  and to  execute  any and all
instruments  for us and in our names in the capacities  indicated  below,  which
said  attorneys-in-fact  and agents,  or either of them,  may deem  necessary or
advisable  to  enable  the  Company  to  comply  with  the Act  and  any  rules,
regulations,  and  requirements  of the  Securities  and Exchange  Commission in
connection  with  such  Report,  including  without  limitation  the  power  and
authority  to  sign  for  us or any of us in  our  names  and in the  capacities
indicated  below any and all amendments to such Report;  and we do hereby ratify
and confirm all that the said  attorneys-in-fact  and agents, or either of them,
shall do or cause to be done by virtue of this power of attorney.

IN  WITNESS  THEREOF,  the  undersigned  have  signed  this  instrument  in  the
capacities and on the dates indicated.

Signature                       Title                             Date
- ---------                       -----                             ----

/s/ Randall L. Marcuson         President, Chief Executive        March 19, 1998
- ------------------------        Officer, and Director
Randall L. Marcuson             

/s/ C.E. Austin                 Director                          March 19, 1998
- ------------------------
Charles E. Austin

/s/ C. Daniel Blackshear        Director                          March 19, 1998
- ------------------------
C. Daniel Blackshear

/s/ Lester M. Crawford          Director                          March 19, 1998
- ------------------------
Lester M. Crawford

/s/ Kenneth N. May              Director                          March 19, 1998
- ------------------------
Kenneth N. May

/s/ Arthur M. Pappas            Director                          March 19, 1998
- ------------------------
Arthur M. Pappas

/s/ Don T. Seaquist             Vice President, Finance           March 19, 1998
- ------------------------        and Administration, and
Don T. Seaquist                 Chief Financial Officer



                                       52

<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     (Replace this text with the legend)
</LEGEND>
<MULTIPLIER>                                   1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                        DEC-31-1997
<PERIOD-START>                           JAN-01-1997
<PERIOD-END>                             DEC-31-1997
<CASH>                                         8,855
<SECURITIES>                                       0
<RECEIVABLES>                                  2,772
<ALLOWANCES>                                       0
<INVENTORY>                                    2,096
<CURRENT-ASSETS>                              13,723
<PP&E>                                        25,628
<DEPRECIATION>                               (14,190)
<TOTAL-ASSETS>                                25,161
<CURRENT-LIABILITIES>                          6,142
<BONDS>                                        3,278
                              0
                                        0
<COMMON>                                          82
<OTHER-SE>                                    15,659
<TOTAL-LIABILITY-AND-EQUITY>                  25,161
<SALES>                                       24,789
<TOTAL-REVENUES>                              24,789
<CGS>                                         12,244
<TOTAL-COSTS>                                 12,244
<OTHER-EXPENSES>                               9,781
<LOSS-PROVISION>                                   0
<INTEREST-EXPENSE>                               582
<INCOME-PRETAX>                                2,182
<INCOME-TAX>                                     422
<INCOME-CONTINUING>                            1,760
<DISCONTINUED>                                     0
<EXTRAORDINARY>                                    0
<CHANGES>                                          0
<NET-INCOME>                                   1,760
<EPS-PRIMARY>                                   0.21
<EPS-DILUTED>                                   0.21
        

</TABLE>

<TABLE> <S> <C>

<ARTICLE>                     5
<RESTATED>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>               DEC-31-1997
<PERIOD-START>                  JAN-01-1997
<PERIOD-END>                    MAR-31-1997
<CASH>                                8,480
<SECURITIES>                          1,379
<RECEIVABLES>                         2,635
<ALLOWANCES>                              0
<INVENTORY>                           1,811
<CURRENT-ASSETS>                     14,035
<PP&E>                               22,530
<DEPRECIATION>                       11,062
<TOTAL-ASSETS>                       25,773
<CURRENT-LIABILITIES>                 7,000
<BONDS>                               5,012
                     0
                               0
<COMMON>                                 81
<OTHER-SE>                           13,680
<TOTAL-LIABILITY-AND-EQUITY>         25,773
<SALES>                               5,925
<TOTAL-REVENUES>                      5,925
<CGS>                                 2,822
<TOTAL-COSTS>                         2,822
<OTHER-EXPENSES>                      2,578
<LOSS-PROVISION>                          0
<INTEREST-EXPENSE>                      200
<INCOME-PRETAX>                         325
<INCOME-TAX>                             63
<INCOME-CONTINUING>                     262
<DISCONTINUED>                            0
<EXTRAORDINARY>                           0
<CHANGES>                                 0
<NET-INCOME>                            262
<EPS-PRIMARY>                          0.03
<EPS-DILUTED>                          0.03
        

</TABLE>

<TABLE> <S> <C>

<ARTICLE> 5
<RESTATED>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-END>                               DEC-31-1996
<CASH>                                           9,036
<SECURITIES>                                       876
<RECEIVABLES>                                    2,313
<ALLOWANCES>                                         0
<INVENTORY>                                      1,758
<CURRENT-ASSETS>                                13,983
<PP&E>                                          21,765
<DEPRECIATION>                                  10,194
<TOTAL-ASSETS>                                  25,554
<CURRENT-LIABILITIES>                            6,431
<BONDS>                                          5,814
                                0
                                          0
<COMMON>                                            80
<OTHER-SE>                                      13,229
<TOTAL-LIABILITY-AND-EQUITY>                    25,554
<SALES>                                         20,632
<TOTAL-REVENUES>                                20,632
<CGS>                                           11,032
<TOTAL-COSTS>                                   11,032
<OTHER-EXPENSES>                                 7,811
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                               1,253
<INCOME-PRETAX>                                    536
<INCOME-TAX>                                       195
<INCOME-CONTINUING>                                341
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                       341
<EPS-PRIMARY>                                    $0.05
<EPS-DILUTED>                                    $0.06
        

</TABLE>

<TABLE> <S> <C>

<ARTICLE>                     5
<RESTATED>
<CIK> 0000878725
<NAME> EMBREX, INC.
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                              DEC-31-1996
<PERIOD-END>                                   SEP-30-1996
<CASH>                                               5,366
<SECURITIES>                                         1,875
<RECEIVABLES>                                        2,230
<ALLOWANCES>                                             0
<INVENTORY>                                          2,062
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                                   EXHIBIT 99

                                  RISK FACTORS

DEPENDENCE ON CERTAIN CUSTOMERS

The  Company's  revenues  are highly  dependent on  expenditures  by the poultry
producing industry.  The Company's  operations could be materially and adversely
affected by a general economic decline in this industry.  The Company has in the
past  derived,  and may in the  future  derive,  a  significant  portion  of its
revenues from a relatively  limited number of customers.  In 1997, one customer,
Tyson Foods, Inc., accounted for approximately 28% of the Company's consolidated
revenues.  Also, Perdue Farms and ConAgra Poultry accounted for approximately 8%
and 7%,  respectively,  of consolidated 1997 revenues.  The Company continues to
experience  such  concentration  in the  current  year and is likely to do so in
future years.  The loss of any such customer could  materially  adversely affect
the Company's revenues.

EFFECT OF ECONOMIC FACTORS ON REVENUES AND EARNINGS

The  Company's  revenues  and  earnings  may be impacted by domestic  and global
economic factors that are beyond the Company's control,  such as fluctuations in
the price of poultry feed,  export  demand for U.S.  poultry  products,  and the
extent to which its cost of  products  and  operating  expenses  could  increase
faster  than  contractual  price  adjustments  with its  customers.  A principal
component of the Company's  revenues is fees charged to customers for the number
of eggs  injected  with the  INOVOJECT(R)  system.  Rising  poultry  feed prices
increase the production costs of commercial poultry producers and may cause them
to reduce  production  which,  in turn,  could  adversely  impact the  Company's
revenues. Adverse economic conditions in markets outside the United States could
also have a negative  impact on the  Company's  revenues  and  earnings in those
markets.

INTERNATIONAL SALES AND MARKETING

The Company  intends to continue its efforts to expand into  markets  outside of
North America.  Sales outside of North America have accounted for  approximately
9%, 10%, and 6% of revenues in fiscal  1997,  1996 and 1995,  respectively.  The
volume  and  consistency  of such sales is subject  to  economic  and  political
conditions  in the markets in which Embrex does  business,  which are beyond the
Company's  control.  In addition,  there is no assurance  that the  INOVOJECT(R)
system will be  successfully  marketed  outside of North  America  since  market
acceptance  is  often  dependent  on the  need  for  biological  products  to be
administered  and on  regulatory  approval  of in ovo  administration  of  these
products.

NO ASSURANCE OF MARKET ACCEPTANCE OR DEVELOPMENT OF NEW PRODUCTS

Embrex's principal existing product,  the INOVOJECT(R)  system, has only been in
full  commercial  use since 1993.  The market  acceptance  of new  technologies,
including those of the Company, is subject to a number of factors, including the
ability of the technology to meet potential  customers'  needs more  effectively
than  competitive  products  or  technologies,  and any  concerns  which  may be
associated with the use of new technology,  such as reliability and maintenance.
Furthermore,  future growth in INOVOJECT(R)  system revenue will be dependent on
markets  outside the United States where  barriers to entry  include  commercial
acceptance  of the  INOVOJECT(R)  system for  prevailing  poultry  diseases  and
regulatory approval of both the INOVOJECT(R) system and biological products.

In addition to the presently marketed  INOVOJECT(R) system,  Embrex, both itself
and together with collaborators, is developing vaccines for control of viral and
parasitic  diseases and products for health and performance  modification  which
are in various  stages of  development.  These products are subject to the risks
inherent in the development of products based on innovative technologies and are
subject to various regulatory approval requirements.

Embrex has developed and commercialized a technology using its proprietary viral
neutralizing  factor  ("VNF(R)") which permits a single dose  immunization of an
egg  embryo for the life of the bird.  The  Company  markets a vaccine  known as
Bursaplex(TM)  which uses Embrex's VNF(R).  The vaccine has been approved by the
United States Department of Agriculture  ("USDA") for in ovo and post-hatch use.
However,  Bursaplex(TM) has only recently been sold in commercial quantities and
there is no assurance  that the product will  continue to be sold in  commercial
quantities even if it is shown to be effective.



                                       55
<PAGE>


The  development and  commercialization  of additional new products will require
substantial testing and development and regulatory approval.

DEPENDENCE ON OTHERS

Embrex   plans  to  continue  to  conduct  its   operations   with  third  party
collaborators,  licensors or  licensees.  While Embrex  believes its present and
future  collaborators,  licensors and licensees will have an economic motivation
to succeed in performing their  obligations  under its agreements with them, the
amount  and  timing  of funds and  other  resources  to be  devoted  under  such
agreements will be controlled by such other parties and are subject to financial
or other difficulties that may befall such other parties.
Thus, no assurance can be given that Embrex will generate any revenues from such
agreements.

Embrex  does not have large  scale  facilities  for the  production  of Embrex's
INOVOJECT(R)  system and  biological  products and does not plan to develop such
facilities in the foreseeable  future.  Embrex  therefore will rely  principally
upon relationships with contract  manufacturers.  There can be no assurance that
manufacture  and  supply  agreements  will be  maintained  on terms and at costs
acceptable to Embrex.

The  Company  has  developed a  strategic  relationship  with a single  contract
manufacturer  to  fabricate  its  INOVOJECT(R)  systems.   While  other  machine
fabricators exist and have constructed limited numbers of INOVOJECT(R)  systems,
a change in  fabricators  could  cause a delay in  manufacturing  and a possible
delay in the timing of future INOVOJECT(R) installations and revenues from those
installations.

The Company has granted Select  Laboratories,  Inc.  ("Select"),  a wholly-owned
subsidiary  of Rhone  Merieux SA,  exclusive  rights to  manufacture  Infectious
Bursal  Disease  vaccines  containing  Embrex's  proprietary  VNF(R) product for
Embrex to market in North  America,  Latin America and Asia under the trade name
Bursaplex(TM). Embrex has also granted Cyanamid Websters ("Websters"), a unit of
Ft. Dodge Animal  Health,  which is a division of American Home Products  Corp.,
exclusive  rights to manufacture and market  Infectious  Bursal Disease vaccines
containing  the Company's  VNF(R)  product to be marketed in Europe,  the Middle
East and Africa under the trade name  Bursamune(TM).  Additionally,  the Company
has one contract  supplier of its VNF(R)  product,  the only  supplier  that was
included in the USDA's approval for in ovo use of Bursaplex(TM). The manufacture
of the bursal disease  vaccines  being produced by Select and Websters,  and the
Company's VNF(R) product,  generally must be performed in licensed facilities or
under approved  regulatory  methods.  Although there are other manufacturers who
are capable of manufacturing bursal disease products and producing products such
as VNF(R),  a change of suppliers  could adversely  affect the Company's  future
operating  results  due to the  time it  would  take a new  supplier  to  obtain
regulatory approval of its production process and/or manufacturing facilities.

In June 1997, the Company  announced that Ft. Dodge Animal Health indicated that
its application for U.K. in ovo regulatory  approval of  Bursamune(TM)  had been
provisionally  refused.  Both the Company and Ft. Dodge had anticipated approval
by the middle of 1997,  however,  Ft. Dodge  indicated that the U.K.  regulatory
authority  requested that further data be supplied.  The Company is working with
Ft. Dodge and  Websters,  which are  responsible  for  obtaining  the  necessary
approvals  for  Bursamune(TM)  in both the U.K.  and  other  European  Community
markets,  to  respond to the U.K.  regulatory  authority  request  for data with
respect to Bursamune(TM). While the Company anticipates that regulatory approval
in the U.K., as well as some other European Community markets, will occur during
the  summer of 1998,  there can be no  assurances  that such  approvals  will be
forthcoming.

POSSIBLE NEED FOR ADDITIONAL FINANCING

From its inception in May 1985 through December 31, 1997,  Embrex had cumulative
operating losses (accumulated deficit) of $38.9 million. Until the first quarter
of 1996, Embrex had incurred operating losses since its inception.  Although the
Company has been  profitable  in 1996 and 1997,  there can be no assurance  that
Embrex will continue to operate profitably.

The  ability  of  Embrex  to  attain  revenues   sufficient  to  meet  its  cash
requirements for operations is dependent upon continued market acceptance of the
INOVOJECT(R)  system on lease terms  acceptable to Embrex and on the  successful
development  and  commercialization  of additional  products.  The extent of the
Company's future revenues, if any, derived



                                       56
<PAGE>


from INOVOJECT(R)  fees is subject to many variables such as whether  additional
agreements for INOVOJECT(R)  systems are reached,  the timing of any agreements,
whether existing or new installation  schedules are met, and the extent to which
customers use the INOVOJECT(R) system.

Although the Company  anticipates  that its existing  funds, as well as revenues
from  operations,  will be adequate to sustain its existing  operations  for the
foreseeable future,  there are no assurances that such funds will be sufficient.
If  additional  funds  become  necessary  to  sustain  existing   operations  or
anticipated  growth, the Company will be required to seek additional  financing,
and there can be no assurance that such financing will be obtainable or that, if
available,  such  financing  will be on terms  favorable  or  acceptable  to the
Company.  Obtaining  additional  financing for such purposes may be difficult or
impossible,  or  financing  may  only  be  available  on  terms  unfavorable  or
unacceptable to the Company.

GOVERNMENT REGULATION AND NEED FOR REGULATORY APPROVAL

Although  the  use of the  INOVOJECT(R)  system  is not  subject  to  regulatory
approval in the U.S., the research and development  activities of Embrex as well
as the  investigation,  manufacture  and sale of poultry health and  performance
enhancement  products are subject to regulation either by the USDA or the United
States Food and Drug  Administration  ("FDA")  and state and  foreign  agencies.
Foreign  agencies  may also require  approval of the  INOVOJECT(R)  system.  The
process of obtaining  governmental  approval is costly and at the USDA generally
takes from one to three years and at the FDA five or more years. There can be no
assurance  that any future  product  that Embrex may develop will be approved by
the USDA, the FDA or any other regulatory agency. Delays in obtaining regulatory
approval may adversely affect the marketing of any products  developed by Embrex
and the ability of Embrex to receive product  revenues and royalties.  There can
be no assurance that  regulatory  approvals for Embrex's future products will be
obtained without lengthy delays, if at all.

Moreover,  Embrex is, or may become, subject to various federal, state and local
laws,  regulations  and  recommendations  relating to safe  working  conditions,
laboratory  and  manufacturing  practices  and the use and disposal of hazardous
substances used in conjunction with Embrex's research work. In addition,  Embrex
cannot  predict  the  extent of  governmental  regulations  which  might have an
adverse effect on the production and marketing of Embrex's products.

Embrex has entered into and intends to continue to enter into licensing or joint
development  agreements  pursuant to which costs  associated with the regulatory
approval  process for some  products  are and will be borne by the  licensees or
joint  developers.  To the extent that  Embrex is unable to generate  sufficient
funds from operations or enter into licensing or joint development agreements to
develop  products,  it may not have the  financial  resources  to  complete  the
regulatory approval process with respect to all or any of the products currently
under development. Products developed by Embrex may not be marketed commercially
in any jurisdiction in which required approvals have not been obtained.

PATENTS AND PROPRIETARY RIGHTS

Certain of Embrex's  products  and certain of the  processes  by which Embrex is
able to produce its products are  proprietary.  Embrex has  ownership  rights to
some of the  technologies  employed  in these  processes,  and some are owned by
others  and  exclusively  licensed  to  Embrex.   Embrex  believes  that  patent
protection  of materials  or  processes  it develops  and any products  that may
result  from  Embrex's  and  licensors'  research  and  development  efforts are
important to the possible  commercialization  of Embrex's  products.  The patent
position of companies such as Embrex  generally is highly uncertain and involves
complex legal and factual  questions.  To date no consistent  policy has emerged
regarding the breadth of claims allowed in biotechnology  patents.  Accordingly,
there can be no assurance that patent applications relating to Embrex's products
or  technology  will  result in patents  being  issued or that,  if issued,  the
patents will afford  protection  against  competitors  with similar  technology.
Moreover,  some  patent  licenses  held by  Embrex  may be  terminated  upon the
occurrence of certain events or become  non-exclusive  after a specified period.
In addition,  companies that obtain patents claiming  products or processes that
are necessary for or useful to the development of Embrex's  products could bring
legal actions against Embrex claiming infringement.  Embrex is currently not the
subject of any patent  infringement claim. There can be no assurance that Embrex
will have the financial  resources necessary to enforce any patent rights it may
hold.  Also,  Embrex may be required to obtain  licenses from others to develop,
manufacture  or market its products.  There can be no assurance that Embrex will
be able to obtain such  licenses on  commercially  reasonable  terms or that the
patents underlying the licenses will be valid and enforceable.



                                       57
<PAGE>


Embrex also relies upon unpatented, proprietary technology, and no assurance can
be given that others will not  independently  develop  substantially  equivalent
proprietary  information  or  techniques  or  properly  gain  access to Embrex's
proprietary  technology,  or  disclose  such  technology,  or  that  Embrex  can
meaningfully protect its rights in such unpatented proprietary technology.

Embrex  attempts  and will  continue  to  attempt  to  protect  its  proprietary
materials and processes by relying on trade secret laws and  non-disclosure  and
confidentiality agreements with its employees and certain other persons who have
access to its  proprietary  materials  or  processes  or who have  licensing  or
research arrangements with Embrex.  Despite these protections,  no assurance can
be given that others  will not  independently  develop or obtain  access to such
materials  or  processes  or that  Embrex's  competitive  position  will  not be
adversely affected thereby.

In September 1996, Embrex filed a patent  infringement suit in the United States
District  Court for the  Eastern  District  of North  Carolina  against  Service
Engineering  Corporation,  a Maryland corporation,  and Edward G. Bounds, Jr., a
Maryland  resident  and  officer of Service  Engineering  Corporation.  The suit
alleged that each of the defendants'  development of an in ovo injection device,
designed  to compete  with  Embrex's  patented  INOVOJECT(R)  injection  method,
infringes  at least  one  claim of the U.S.  patent  No.  4,458,630  exclusively
licensed to Embrex for the in ovo  injection  of vaccines  into an avian  embryo
(the "Sharma Patent").  Further, Embrex claims that the defendants have violated
the terms of a Consent  Judgment  and  Settlement  Agreement  entered  into with
Embrex in November 1995 in which prior  litigation  was  concluded  with Service
Engineering and Bounds agreeing not to engage in future activities violating the
Sharma Patent.  Embrex sought injunctive  relief to prevent  infringement of the
Sharma Patent as well as monetary damages. In November 1996, Service Engineering
Corporation and Edward G. Bounds responded to Embrex's patent  infringement suit
by  asserting   various   affirmative   defenses  and  denying  the  substantive
allegations  in  Embrex's  complaint.  This  suit is  still  pending  and  final
disposition is expected in 1998. The outcome of this litigation is uncertain and
there is no  assurance  that Embrex will  prevail on the merits or  successfully
defend the validity of its patent.

In March 1997, Service  Engineering  Corporation,  a Maryland  corporation,  and
Edward G. Bounds, Jr., a Maryland resident and an officer of Service Engineering
Corporation,  filed suit against the United States  Department of Agriculture in
the United  States  District  Court for the District of Maryland with respect to
its grant to Embrex of an exclusive license for the Sharma Patent. The complaint
alleges that the USDA did not  adequately  comply with  statutory and regulatory
requirements in making the grant to Embrex of an exclusive license to the Sharma
Patent,  the revision of the  exclusive  license in 1991 and the revision of the
exclusive license in 1994, which extended the period of exclusivity,  originally
set to  terminate  on December 31,  1996,  through the patent  expiration  date.
Plaintiffs  allege that in December 1996 (after Embrex had  instituted the above
referenced  action  for  patent  infringement  and  breach  of  contract),   the
Plaintiffs  requested the USDA to grant them a license of the Sharma Patent. The
Plaintiffs  allege that the USDA refused to do so because the USDA said that the
license  was not  available  and that the  Plaintiffs  had no basis for  relief.
Plaintiffs also allege that the USDA wrongfully  consented to Embrex's  bringing
suit against the Plaintiffs.  Plaintiffs are seeking to have the court set aside
the  extension of the  exclusive  license,  the USDA's grant of  permission  for
Embrex to sue Service Engineering  Corporation,  Edwards G. Bounds, Jr. and IGI,
Inc. for patent infringement, the USDA's refusal to grant to Service Engineering
Corporation a non-exclusive  license to the Sharma Patent and the USDA's refusal
to act favorably upon Service Engineering  Corporation's appeal from the refusal
to grant it a non-exclusive  license.  In addition,  Plaintiffs seek to have the
court issue an order requiring the USDA, prior to granting any exclusive license
under the Sharma  Patent,  including  by  extending  the term of a  pre-existing
exclusive  license,   to  observe  the  procedures  set  forth  under  laws  and
regulations governing the grant of licenses to patents owned by the USDA, and to
remand  the  matter to the USDA to take  action in  accordance  with the  order.
Plaintiffs  also seek  attorneys'  fees and costs  from the USDA.  This suit was
stayed in January 1998 for 60 days pending resolution of the suit between Embrex
and Service  Engineering  Corporation  and Edward G. Bounds,  Jr. The outcome of
this  litigation is uncertain and there is no assurance that its resolution will
be favorable to Embrex.

DEPENDENCE ON KEY PERSONNEL

Embrex's  ability to develop  marketable  products  and  maintain a  competitive
research and  technological  position  will depend on its ability to continue to
attract and retain  experienced  and highly  educated  scientific and management
personnel and advisors.  Competition for qualified employees among biotechnology
companies  is intense and the loss of key  scientific  or  management  personnel
would adversely  affect Embrex.  Embrex has obtained  insurance in the amount of
$1,000,000 on the life of Randall L. Marcuson, its President and Chief Executive
Officer, of which Embrex is the sole beneficiary. There can be no assurance that
Embrex will be able to continue to attract and retain qualified  staff.  


                                       58
<PAGE>


SUPPORT AND MAINTENANCE REQUIREMENTS

The  Company is required  to supply,  support,  and  maintain  large  numbers of
INOVOJECT(R)  systems  at its  customers'  hatcheries  on a  timely  basis  at a
reasonable cost to the Company.  There can be no assurance that the Company will
be able to continue to provide such services on a cost-effective basis.

TECHNOLOGY AND COMPETITION

The areas of  technology  in which  Embrex is involved  are subject to rapid and
significant technological change. Competitors include independent companies that
specialize  in  biotechnology  as  well as  major  chemical  and  pharmaceutical
companies,  universities, and public and private research organizations, many of
which are well established and have substantially greater marketing,  financial,
technological and other resources than Embrex.  There can be no assurance that a
competitive  delivery method,  either within or outside the United States,  will
not be developed and gain commercial acceptance. Also, there can be no assurance
that competitors  will not succeed in developing  technologies and products that
are more effective than any which have been or are being  developed by Embrex or
which would render Embrex's technology and products obsolete or non-competitive.

ISSUANCE OF PREFERRED STOCK; SHAREHOLDER RIGHTS PLAN; ANTI-TAKEOVER EFFECTS

The Board of Directors  has the  authority to issue up to  15,000,000  shares of
Preferred  Stock  in one or  more  series  and to  determine  the  designations,
preferences  and relative  participating,  optional or other special  rights and
qualifications,  limitations or restrictions thereof, of the shares constituting
any  series  of  Preferred  Stock,  without  any  further  vote or action by the
shareholders.  The issuance of Preferred  Stock by the Board of Directors  could
affect the rights of the holders of Common  Stock.  For example,  such  issuance
could result in a class of securities  outstanding  that would have  preferences
with respect to voting rights and dividends and in  liquidation  over the Common
Stock,  and  could  (upon  conversion  or  otherwise)  enjoy  all of the  rights
appurtenant to Common Stock.

The  authority  of the  Board  of  Directors  to  issue  Preferred  Stock  could
potentially  be used to discourage  attempts by others to obtain  control of the
Company through merger,  tender offer, proxy contest or otherwise by making such
attempts  more  difficult to achieve or more costly.  The Board of Directors may
issue the  Preferred  Stock  without  shareholder  approval  and with voting and
conversion  rights which could adversely  affect the voting power of the holders
of Common Stock.  There are no agreements or understandings  for the issuance of
Preferred Stock and the Board of Directors has no present intention to issue any
Preferred Stock.

Embrex  adopted  a  shareholder  rights  plan  which  could  have the  effect of
discouraging  a takeover of the Company.  The rights plan, if  triggered,  would
make it more  difficult to acquire the Company by, among other things,  allowing
existing  shareholders to acquire  additional shares at a substantial  discount,
thus  substantially  inhibiting an acquiror's  ability to obtain  control of the
Company.

UPGRADE TO COMPANY'S INTERNAL SYSTEMS AND YEAR 2000 COMPLIANCE

The efficient  management of  information is critical to the Company as it grows
and the complexity of its business increases.  The Company believes that keeping
pace with  technological  advances in this area is  important  to the  Company's
continued  success.  As a result, the Company intends to continue to upgrade its
internal  systems  and  software.  As the year  2000  approaches,  an  important
business  issue have emerged  regarding  how existing  application  software and
operating  systems can accommodate  this date value.  Many existing  application
software products,  including the Company's, were designed to accommodate only a
two-date year. For example, "98" may be stored on a system to represent 1998 and
"00" represents 1900.  Irrespective of the Year 2000 issue, the Company needs to
upgrade its accounting  system to meet the demands of its business.  The Company
is developing plans for the upgrade of its software and hardware as necessary to
address both its increased internal needs and the impact of the year 2000 on its
systems. The Company believes that the additional costs associated with the Year
2000 aspects of the upgrade will be immaterial.  The inability of the Company or
its software and hardware  vendors to upgrade the Company's  systems in a manner
that fully  addresses the Company's  needs and the year 2000 issue could have an
adverse impact on the Company's ability to produce the information  necessary to
manage its business,  communicate with its customers and suppliers,  and prepare
financial statements.



                                       59


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