INCYTE GENOMICS INC
424B3, 2000-10-25
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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PROSPECTUS SUPPLEMENT                           Filed pursuant to Rule 424(b)(3)
to Prospectus dated August 2, 2000                    Registration No. 333-36318



                                  $200,000,000

                              INCYTE GENOMICS, INC.

                  5.5% CONVERTIBLE SUBORDINATED NOTES DUE 2007
                                       and
                             SHARES OF COMMON STOCK
                      ISSUABLE UPON CONVERSION OF THE NOTES

     This prospectus supplement relates to the resale by the holders of 5.5%
convertible  subordinated notes due 2007 of Incyte Genomics, Inc. and the shares
of common stock issuable upon conversion of the notes.

     This  prospectus  supplement  should  be read in  conjunction  with the
prospectus  dated August 2, 2000,  which is to be delivered with this prospectus
supplement.

     The  information  in the table  appearing  under the  heading  "Selling
Securityholders" in the prospectus is supplemented and superseded in part by the
information appearing in the table below:
<TABLE>
<CAPTION>

                                                   Principal                                         Common Stock
                                                Amount of Notes    Common Stock                      Owned After
                                                  Beneficially    Issuable Upon                       Completion
                                                   Owned and        Conversion      Common Stock        of the
                      Name                         Offered(1)    of the Notes(1)     Offered(1)      Offering(1)
                      ----                      ---------------  ---------------    ------------     ------------
<S>                                              <C>                 <C>               <C>               <C>

Deutsche Bank Securities Inc...................  $3,800,000          28,181            28,181            --

                             ----------------------
<FN>

(1)  Amounts  indicated may be in excess of the total amount registered due
     to sales or transactions  exempt from the registration requirements of
     the Securities Act of 1933 since the date on which selling
     securityholders provided information to us regarding their notes.

     None of the selling securityholders listed above nor any of their
     affiliates, officers, directors or principal equity holders has held
     any  position or office or has had any  material relationship with us
     within the past three years.

</FN>
</TABLE>

                              --------------------

     Investing in the notes and our common  stock  involves a high degree of
risk. You should carefully read and consider the "Risk  Factors" beginning on
page 3 of the prospectus.

                              --------------------

     Neither the Securities and Exchange Commission nor any state securities
commission has approved or  disapproved of these securities or passed upon the
accuracy or adequacy of this prospectus supplement or the prospectus.  Any
representation to the contrary is a criminal offense.

                              --------------------


           The date of this Prospectus Supplement is October 25, 2000.



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