EPIGEN INC /DE
8-K, EX-3.15, 2000-08-08
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                  EXHIBIT 3.15

                           CERTIFICATE OF AMENDMENT OF

                       DESIGNATION, PREFERENCES AND RIGHTS

                                       OF

                            SERIES B PREFERRED STOCK

                                       OF

                                  EPIGEN, INC.


         EPIGEN,  INC., a corporation  organized and existing  under the laws of
the State of Delaware (the  "Corporation),  in accordance with the provisions of
Section 151 of the General Corporation Law of the State of Delaware, does hereby
CERTIFY:

         1. The  Certificate of  Incorporation,  as amended,  of the Corporation
fixes the total  number of shares of all  classes  of  capital  stock  which the
Corporation  shall have  authority to issue as Sixty-Five  Million  (65,000,000)
shares,  of which Fifty Million  (50,000,000)  shares shall be Common Stock, par
value $.001 per share (the "Common  Stock"),  and Fifteen  Million  (15,000,000)
shares  shall be shares of  Preferred  Stock,  par  value  $.001 per share  (the
"Preferred Stock").

         2. The Certificate of  Incorporation,  as amended,  of the Corporation,
expressly  grants to the Board of  Directors  of the  Corporation  authority  to
provide for the issuance of said  Preferred  Stock in one or more  series,  with
such  voting  powers,  and with such  designations,  preferences  and  relative,
participating, optional or other special rights, and qualifications, limitations
or restrictions  thereof,  as shall be stated and expressed in the resolution or
resolutions providing for the issue thereof adopted by the Board of Directors as
are not stated and expressed in its Certificate of Incorporation, as amended.

         3. Pursuant to authority  conferred  upon the Board of Directors by the
Certificate of Incorporation,  as amended, the Board of Directors,  at a meeting
duly  held on June 17,  1996,  at which a quorum  was duly  present  and  acting
throughout,  duly authorized and adopted the provisions  establishing a Series B
Preferred  Stock of the  Corporation  pursuant to a Certificate of  Designation,
Preferences  and Rights of Series B Preferred  Stock filed with the Secretary of
State of Delaware on June 18, 1996.  All of the  outstanding  shares of Series B
Preferred  Stock were  acquired  by the  Corporation  pursuant to an exchange of
shares of its Common  Stock for such  outstanding  shares of Series B  Preferred
Stock on July 14, 1997 and  restored to the status of  authorized  but  unissued
shares of preferred stock, without designation.  Pursuant to authority conferred
upon the Board of Directors by the Certificate of Incorporation, as amended, the
Board of  Directors,  at a meeting duly held on June 7, 2000,  at which a quorum
was duly  present  and  acting  throughout,  duly  authorized  and  adopted  the
provisions set forth in the following

                                      -13-

<PAGE>

resolution providing for an Amended Certificate of Designation,  Preferences and
Rights of Series B Preferred Stock as follows:

         RESOLVED,  that an issue of a series of the Preferred  Stock, par value
$.001  per  share,  of the  Corporation  consisting  of  Five  Hundred  Thousand
(500,000)  shares is hereby  provided  for, and the voting  power,  designation,
preferences and relative,  participating,  optional or other special rights, and
the  qualifications,  limitations or restrictions  thereof,  are fixed hereby as
follows:

                  1.  DESIGNATION.  The  designation  of such  series  shall  be
         "Series B Preferred  Stock"  (hereinafter  referred to as the "Series B
         Preferred Stock") and the number of shares  constituting such series is
         Five Hundred  Thousand  (500,000).  The number of authorized  shares of
         Series B  Preferred  stock  may be  increased  or  reduced  by  further
         resolutions  of the board of Directors of the  Corporation  or any duly
         authorized  committee  thereof  and  by  the  filing  of a  certificate
         pursuant to the provisions of the General  Corporation Law of the State
         of  Delaware  stating  that  such  increase  or  reduction  has been so
         authorized,  but the number of shares of Series B Preferred Stock shall
         not be reduced  below  500,000  unless there shall be less than 500,000
         shares of  Series B  Preferred  Stock  outstanding,  in which  case the
         number of shares of Series B Preferred Stock may be reduced to a number
         of shares equal to the number of such shares  outstanding  from time to
         time.  Shares  of  Series  B  Preferred  Stock  shall be  evidenced  by
         certificates registered in the name of the record holder of such shares
         of Series B Preferred Stock.

                  2.  DIVIDENDS.  The Series B Preferred Stock shall be entitled
         to share pari passu on a share for share basis with the Common Stock of
         the  Corporation  if, in any  dividends if, as and when declared by the
         Corporation's Board of Directors.

                  3.  MANDATORY  REDEMPTION.  The  shares of Series B  Preferred
         Stock shall be redeemed  by the  Corporation  not later than August 31,
         2001 (the "Redemption  Date") at a price per share of $1.00;  provided,
         however, that the Corporation shall have the right at any time prior to
         the  Redemption  Date to  repurchase  all or any  portion  of the  then
         outstanding  shares of Series B  Preferred  Stock,  pro rata,  from the
         holders thereof providing it has funds legally available therefor.  Any
         such repurchase shall be upon thirty (30) days' prior written notice to
         the holders of the shares of Series B  Preferred  Stock,  which  notice
         shall set forth the number of shares of Series B Preferred  Stock to be
         repurchased  from the holder  receiving  such notice,  the date of such
         repurchase (the  "Repurchase  Date"),  and  instructions  for tendering
         certificates  representing the shares of Series B Preferred Stock to be
         repurchased.  From and after any Repurchase Date, the holders of shares
         of Series B Preferred shall have no rights as shareholders with respect
         to the shares of Series B Preferred Stock so purchased, but shall stand
         as creditors of the Corporation for the amount of the repurchase  price
         therefor.

                  4.  SHARES TO BE  RETIRED.  All  shares of Series B  Preferred
         Stock  redeemed or  purchased by the  Corporation  shall be retired and
         canceled and shall be restored to the status of authorized but unissued
         shares of Preferred Stock,  without  designation as to series,  and may
         thereafter be issued, but not as shares of Series B Preferred Stock.

                                      -14-

<PAGE>

                  5.  CONVERSION OR EXCHANGE.

                  (a) CONVERSION  RIGHT.  Except as set forth in subsection 5(c)
         hereof, at any time prior to the Mandatory Redemption Date set forth in
         Section 3 hereof,  the holders of Series B  Preferred  Stock shall have
         the right at any time to convert  all,  but not less than all,  of such
         shares of Series B  Preferred  Stock into  shares of the  Corporation's
         Common  Stock or such other  securities  into which such  Common  Stock
         shall have been converted,  or by which the Corporation's  Common Stock
         shall have been  replaced,  at the rate of one share of Common Stock of
         the Corporation for each share of Series B Preferred Stock.

                  (b) MANDATORY  CONVERSION.  In the event the Corporation shall
         engage  in  an  "equity   financing"  for  Common  Stock  and/or  other
         securities of the Corporation then each  outstanding  share of Series B
         Preferred  Stock must be converted by the holders of Series B Preferred
         Stock into Common Stock and/or other  securities of the  Corporation at
         one of the following rates: (i) the amount of shares of Common Stock or
         other securities of the Corporation set forth in Section 5(a) hereof or
         (ii) that number of shares of Common Stock and/or other  securities  of
         the  Corporation to be offered in such equity  financing  determined by
         (A) dividing the aggregate  purchase  price paid by such holder for his
         or her shares of Series B  Preferred  Stock by the  aggregate  purchase
         price paid by the  purchasers of the  Corporation's  securities in such
         equity  financing and (B)  multiplying  the  resulting  quotient by the
         number of  shares  of  Common  Stock  and/or  other  securities  of the
         Corporation to be issued in such equity financing. For purposes of this
         provision, the term "equity financing" shall mean the sale the sale, in
         one or more  transactions or offerings by the Corporation of its shares
         of Common Stock and/or other  securities  resulting in aggregate  gross
         proceeds to the Corporation of not less than  $2,000,000.  In the event
         the equity financing shall involve  transactions  with different terms,
         any election by a holder of Series B Preferred  Stock to convert his or
         her shares Series B Preferred Stock pursuant to subsection (ii) of this
         Section  5(b)  shall  be  pro  rata  among  the  various   transactions
         constituting the equity financing.

                  (c) NOTICE OF CONVERSION.  Any holder of outstanding shares of
         Series B Preferred  Stock may elect to convert  such shares of Series B
         Preferred  Stock into shares of Common Stock by serving  written notice
         on the  Corporation  setting  forth  (1) the  number  of shares of such
         holder's  Series B  Preferred  Stock to be  converted;  (2) the date by
         which such conversion must occur,  such date being at least twenty (20)
         and not more  than  sixty  (60)  days  after  the date of such  notice;
         provided, however, that in the event the Company exercises its right to
         redeem the Series B Preferred  Stock prior to the Mandatory  Redemption
         Date set forth in Section 3 hereof,  the  holders of Series B Preferred
         Stock shall have the right to elect to convert pursuant to Section 5(a)
         hereof  at any time  prior to such  early  redemption  date by  written
         notice to that effect received by the Corporation prior to the date set
         forth in the Corporation's notice of early redemption; (3) whether such
         shares of Common  Stock or other  securities  are to be  evidenced by a
         single  certificate or multiple  certificates (in which latter case the
         denominations of such certificates shall also be set forth); and (4) if
         such certificates are to be issued in the name

                                      -15-

<PAGE>

         or names of a person or  persons  other  than that of the holder of the
         Series B Preferred Stock so converting,  the name(s) and address(es) of
         such other person(s). Any securities issued pursuant to this subsection
         (b)(ii) shall be in addition to any securities  actually issued in such
         equity financing.

                  (d) ISSUANCE OF CERTIFICATES. Promptly following the effective
         date  of  any  conversion  in  accordance  with  this  Section  5,  the
         Corporation shall issue a certificate or certificates evidencing shares
         of Common Stock and/or other  securities of the Corporation  into which
         such  shares  of  Series B  Preferred  Stock  have  been  converted  in
         accordance with this Section 5.

                  6.  CERTAIN ADJUSTMENTS.

                  (a) STOCK DIVIDENDS,  SPLITS AND COMBINATIONS.  If at any time
         or from time to time,  the holders of Common Stock  become  entitled to
         receive  additional  shares or less shares because of a stock dividend,
         stock split or combination of shares,  the number of outstanding shares
         of   Series   B   Preferred   Stock   shall  be   proportionately   and
         correspondingly adjusted.

                  (b)  RECLASSIFICATIONS.  If at any time or from  time to time,
         the  holders of Common  Stock  become  entitled  to receive a different
         class of stock (the  "Entitlement  Event"),  any holder of  outstanding
         shares of Series B  Preferred  Stock  shall be  entitled to receive the
         same  number  and kind of  shares of stock as a holder of shares of the
         Common Stock immediately prior to the Entitlement Event was eligible to
         receive with respect to such Common Stock  pursuant to the  Entitlement
         Event. This provision shall include any  reclassification in connection
         with a merger of another corporation into the Corporation.

                  (c) MERGER INTO OR SALE OF ASSETS TO ANOTHER  CORPORATION.  If
         at any time or from  time to time,  the  holders  of the  Common  Stock
         become entitled to receive stock, securities,  property or cash (or any
         combination  of  them)  by  reason  of  a  capital   reorganization  or
         dissolution,  liquidation  or winding-up of the  Corporation,  a merger
         with,  a  consolidation  of the  Corporation  into,  a  sale  of all or
         substantially  all  of  the  assets  of  the  Corporation  to,  another
         corporation  (the  "Reorganization  Event"),  each  holder of shares of
         Series B  Preferred  Stock shall be entitled to receive the same stock,
         securities,  property or cash (or  combination  of them) as a holder of
         the same number of shares of the Common  Stock was  eligible to receive
         with respect to such Common Stock pursuant to the Reorganization Event.

                  7. VOTING RIGHTS.  The holders of shares of Series B Preferred
         Stock shall be  entitled,  at all meetings of the  Stockholders  of the
         Corporation  and on all occasions  where  stockholders  are entitled to
         vote or give their consent,  to one (1) vote for each share of Series B
         Preferred  Stock  owned by them.  The  holders  of  shares  of Series B
         Preferred  Stock shall vote with the holders of shares of Common  Stock
         as a single class on all matters,  except to the extent that holders of
         Common  Stock or holders of Series B Preferred  Stock shall be entitled
         to vote as a

                                      -16-

<PAGE>

         separate class only on matters which effect the rights, preferences and
         privileges of the Series B Preferred Stock.

                  8.  LIQUIDATION  PREFERENCE.  In the event of any voluntary or
         involuntary liquidation,  dissolution or winding up of the Corporation,
         the  holders  of the  Series B  Preferred  Stock  shall  entitled  to a
         liquidation preference of $1.00 per share, payable out of the assets of
         the  Corporation  therefor  prior to any  payment to the holders of the
         Corporation's  Series A Preferred  Stock of Common Stock.  In the event
         the assets of the  Corporation are not sufficient to pay such amount in
         full,  the  assets  legally  available  therefor  shall  be paid to the
         holders of Series B Preferred  Stock,  pro rata. The  consolidation  or
         merger of the Corporation  with or into any other  corporation,  or the
         sale  of  substantially  all  of  the  assets  of  the  Corporation  in
         consideration   for  the  issuance  of  equity  securities  of  another
         corporation,  shall not be regarded as a  liquidation,  dissolution  or
         winding up of the Corporation within the meaning of this Section 7, but
         only if such  consolidation,  merger or sale of assets shall not in any
         way impair  the  voting  power,  preferences  or special  rights of the
         Series B Preferred Stock.

                  9.  LIMITATIONS ON DIVIDENDS ON JUNIOR RANKING STOCK.  So long
         as any Series B Preferred Stock shall be  outstanding,  the Corporation
         shall not declare any  dividends on the Common Stock or any other stock
         of the Corporation  ranking as to dividends or  distributions of assets
         junior to the Series B Preferred  Stock (any such junior  ranking stock
         being  herein  referred to as "Junior  Stock"),  or make any payment on
         account of, or set apart money for, a sinking or other  analogous  fund
         for the  purchase,  redemption  or other  retirement  of any  shares of
         Junior Stock, or make any distribution in respect  thereof,  whether in
         cash or property or in obligations or stock of the  Corporation,  other
         than  Junior  Stock  (such  dividends,   payments,  setting  apart  and
         distributions being herein called "Junior Stock Payments"),  unless the
         Corporation  shall not be in default or in arrears  with respect to any
         sinking or other  analogous fund or any call for tenders  obligation or
         other agreement for the purchase, redemption or other retirement of any
         shares of Preferred Stock other than Junior Stock. For purposes of this
         Section 9, the  Corporation's  Series A Preferred Stock shall be deemed
         Junior Stock.

                  10. RESTRICTIONS ON TRANSFER.

                  (a)  RESTRICTIONS ON TRANSFER.  Neither the Series B Preferred
         Stock, nor any interest therein,  shall be transferable except upon the
         conditions  specified in this Section 10, which conditions are intended
         to ensure  compliance  with the Securities Act of 1933, as amended (the
         "Securities  Act") and all applicable  state securities laws in respect
         of the transfer of any such securities or any interest therein.

                  (b) RESTRICTIVE LEGEND. Each certificate,  if shares of Series
         B Preferred  Stock shall issued in  certificated  form,  shall  (unless
         otherwise  permitted  by the  provisions  of this Section 10) include a
         legend in a form similar to the following:

                                      -17-

<PAGE>

                  NEITHER THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE
         SECURITIES INTO WHICH THEY ARE CONVERTIBLE  HAVE BEEN REGISTERED  UNDER
         THE SECURITIES ACT OF 1933, AS AMENDED,  AND NEITHER SUCH SECURITIES NO
         ANY  INTEREST  THEREIN MAY BE SOLD,  TRANSFERRED,  PLEDGED OR OTHERWISE
         DISPOSED OF IN THE ABSENCE OF  REGISTRATION  OR AN EXEMPTION  THEREFROM
         UNDER  SUCH ACT,  APPLICABLE  STATE  SECURITIES  LAWS AND THE RULES AND
         REGULATIONS THEREUNDER.

                  (c)  NOTICE OF  PROPOSED  TRANSFER.  Each  holder of shares of
         Series B Preferred  Stock, by his acceptance of such shares,  agrees to
         comply in all respects with the provisions of this Section 10. Prior to
         any proposed transfer of any shares of Series B Preferred Stock, except
         in the case of registration  thereof  pursuant to the Securities Act of
         1933, as amended,  the holder  thereof shall give written notice to the
         Corporation of such holder's  intention of effect such  transfer.  Each
         such  notice  shall  describe  the  manner  and  circumstances  of such
         transfer  in  reasonable  detail,  and  shall be  accompanied  by (i) a
         written opinion of counsel reasonable  satisfactory to the Corporation,
         addressed to the Corporation,  to the effect that the proposed transfer
         may be effected  without  registration of the Series B Preferred Stock,
         or (ii)  written  assurance  from the  Securities  Exchange  Commission
         ("SEC")  that the SEC will not  recommend  any action be taken by it in
         the event such  transfer is effected  without  registration  under such
         Act.  Such proposed  transfer may be effected  only if the  Corporation
         shall have  received such notice and such opinion of counsel or written
         assurance,  whereupon  the holder of such  shares of Series B Preferred
         Stock shall be  entitled to transfer  such shares of Series B Preferred
         Stock in  accordance  with the terms of such notice.  Each  certificate
         evidencing shares of Series B Preferred Stock so transferred shall bear
         the legend set forth in Section 10(b) hereof,  and each  uncertificated
         share of Series B Preferred  Stock so  transferred  shall have  entered
         against it in the Corporation's  stock transfer ledger or other similar
         records a "stop transfer" legend, except that either such legend may be
         removed  if the  opinion of  counsel  or  written  assurance  is to the
         further effect that no such legend nor the  restrictions on transfer in
         this  Section 10 are required in order to ensure  compliance  with such
         Act.

                  11.  PREEMPTIVE  RIGHTS.  The  holders  of  shares of Series B
         Preferred Stock shall not be entitled to any preemptive or preferential
         rights for the  subscription  to any shares of any capital stock of the
         Corporation.

         IN WITNESS  WHEREOF,  the Corporation has caused this Certificate to be
signed by Donald C.  Fresne,  its  President,  who affirms,  under  penalties of
perjury,  that this  Certificate is the act and deed of the Corporation and that
the facts stated herein are true, as of the 7th th day of June, 2000.

                                       EPIGEN, INC.

                                       By: /s/ Donald C. Fresne
                                           ----------------------
                                           Name: Donald C. Fresne
                                           Title: President

                                      -18-



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