BIOWHITTAKER INC
S-8, 1996-09-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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   As filed with the Securities and Exchange Commission on
                     September 11, 1996
                                       Registration No. 333-

             SECURITIES AND EXCHANGE COMMISSION
                   Washington, D.C.  20549
                   _______________________

                          FORM S-8

                   REGISTRATION STATEMENT
                            UNDER
                 THE SECURITIES ACT OF 1933
                  ________________________

                     BIOWHITTAKER, INC.
   (Exact name of registrant as specified in its charter)

           Delaware                     95-3917176
 (State or other jurisdiction(I.R.S. Employer Identification
No.)
of incorporation or organization)

     8830 Biggs Ford Road
    Walkersville, Maryland              21793-0127
(Address of Principal Executive Offices)(Zip Code)

   BioWhittaker, Inc. 1991 Long-Term Stock Incentive Plan
                  (Full title of the plan)

                   F. Dudley Staples, Jr.
                     BioWhittaker, Inc.
                    8830 Biggs Ford Road
             Walkersville, Maryland  21793-0127
           (Name and address of agent for service)

                       (301) 898-7025
    (Telephone number, including area code, of agent for
                          service)

               CALCULATION OF REGISTRATION FEE
 Title of     Amount    Proposed     Proposed    Amount of
Securities    to Be     Maximum      Maximum    Registratio
   to Be     Registe    Offering    Aggregate    n Fee (1)
Registered     red     Price per     Offering
                       Share (1)    Price (1)
  Common     500,000                                  
   Stock      Shares    $6.8125     $3,406,250   $1,174.57
 $.01 Par
   Value

     (1)  Estimated pursuant to Rule 457(h) under the
Securities Act of 1933 based upon the average of the high
and low prices for the Registrant's Common Stock reported on
the New York Stock Exchange Composite Tape on September 10,
1996 solely for the purpose of calculating the registration
fee.
                              


<PAGE>
                           PART II
                              
     INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

    In order to register an additional 500,000 shares of the
common  stock,  par value $.01 per share,  of  BioWhittaker,
Inc.  (the "Registrant") in connection with the Registrant's
1991  Long-Term Stock Incentive Plan, the Registrant  hereby
incorporates herein by reference its Registration  Statement
on  Form  S-8  (Registration No. 33-46139)  filed  with  the
Securities and Exchange Commission on March 4, 1992.

                          EXHIBITS

    The following is a complete list of exhibits filed as
part of this Registration Statement:

<TABLE>
<CAPTION>
  Exhibit                 Description
  Number
     
<S>         <C>
5           Opinion of F. Dudley Staples, Jr.,
            General Counsel of the Registrant,
            with respect to the legality of the
            securities registered under this
            Registration Statement
            
23.1        Consent of F. Dudley Staples, Jr.
            (included in Exhibit 5)
            
23.2        Consent of Ernst & Young LLP
            
</TABLE>

                              2
<PAGE>
                         SIGNATURES

    Pursuant to the requirements of the Securities Act of
1933, the Registrant certifies that it has reasonable
grounds to believe that it meets all the requirements for
filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Walkersville,
State of Maryland, on August 6, 1996.


                             BIOWHITTAKER, INC.

                             By:  /s/ NOEL L. BUTERBAUGH
                               Noel L. Buterbaugh
                               President and Chief Executive
                               Officer

      KNOW ALL MEN BY THESE PRESENTS, that each person whose
signature  appears below constitutes and  appoints  Noel  L.
Buterbaugh  and F. Dudley Staples, Jr., or either  of  them,
his  true and lawful attorneys-in-fact and agents, with full
power of substitution and resubstitution, for him and in his
name,  place and stead, in any and all capacities,  to  sign
any  and all amendments to this registration statement,  and
to  file  the  same,  with all exhibits thereto,  and  other
documents  in  connection herewith, with the Securities  and
Exchange Commission, granting unto each of said attorneys-in-
fact  and agents, full power and authority to do and perform
each  and every act and thing requisite and necessary to  be
done,  as  fully to all intents and purposes as he might  or
could do in person, hereby ratifying and confirming all that
each of said attorneys-in-fact and agents, or his substitute
or  substitutes,  may lawfully do or cause  to  be  done  by
virtue hereof.

      Pursuant to the requirements of the Securities Act  of
1933,  this  registration statement has been signed  by  the
following  persons  in  the  capacities  and  on  the   date
indicated.

  Signature and Capacity                          Date


/s/ NOEL L. BUTERBAUGH                           August 6,
1996
Noel L. Buterbaugh
President, Chief Executive Officer and Director
(Principal Executive Officer)

/s/ PHILIP L. ROHRER, JR.                        August 6,
1996
Philip L. Rohrer, Jr.
Vice President and Chief Financial Officer
(Principal Financial Officer and
Principal Accounting Officer)

                              3
<PAGE>

  Signature and Capacity                          Date


/s/ JOSEPH F. ALIBRANDI                           August 6,
1996
Joseph F. Alibrandi, Director


/s/ RUDIGER ERCKEL                           August 6, 1996
Rudiger Erckel, Director

/s/ STANLEY M. LEMON                             August 5,
1996
Stanley M. Lemon, Director

/s/ JOHN L. SEVER                            August 6, 1996
John L. Sever, Director

/s/ THOMAS R. WINKLER                            August 2,
1996
Thomas R. Winkler, Director

                              4
<PAGE>
                        EXHIBIT INDEX



         Listed below are the Exhibits filed herewith and
which appear immediately hereafter.

<TABLE>
<CAPTION>
  Exhibit                 Description                   
  Number
     
<S>         <C>                                     
5           Opinion of F. Dudley Staples, Jr.,      
            General Counsel of the Registrant,
            with respect to the legality of the
            securities registered under this
            Registration Statement
            
23.1        Consent of F. Dudley Staples, Jr.       
            (included in Exhibit 5)
            
23.2        Consent of Ernst & Young LLP            
</TABLE>
                              5


                                                   Exhibit 5
                                                            
August 12, 1996


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549

Subject:  SEC Registration Statement for shares issuable
under               the BioWhittaker, Inc. 1991 Long-Term
Incentive Plan

Ladies and Gentlemen:

I am the general counsel of BioWhittaker, Inc.
("BioWhittaker") and am rendering this opinion in connection
with the registration on Form S-8 under the Securities Act
of 1933, as amended, of an additional 500,000 shares of
BioWhittaker's Common Stock $.01 par value (the
"BioWhittaker Common Stock") deliverable in accordance with
the BioWhittaker, Inc. 1991 Long-Term Stock Incentive Plan,
as amended through March 5, 1996 (the "Plan").

I have examined originals or copies, certified or otherwise
identified to my satisfaction, of such documents, corporate
records, certificates of public officials and other
instruments relating to the adoption of the amendment to the
Plan as I have deemed necessary or advisable for the
purposes of this opinion.

Upon the basis of the foregoing, I am of the opinion that
the BioWhittaker Common Stock deliverable upon exercise of
the options issued pursuant to the Plan are duly authorized
and, when issued in accordance with the terms of the Plan,
will be legally issued, fully paid and nonassessable.

I hereby consent to the filing of this opinion as an exhibit
to the Registration Statement for the Plan on Form S-8.

Very truly yours,

/s/F. DUDLEY STAPLES, JR.
F. Dudley Staples, Jr.
Secretary and General Counsel


                                                Exhibit 23.2
                                                            
               Consent of Independent Auditors
                              
    We consent to the incorporation by reference in the
Registration Statement (Form S-8 No. 333-_____) pertaining
to the BioWhittaker, Inc. 1991 Long-Term Stock Incentive
Plan of our report dated December 21, 1996, except for Note
12, as to which the date is January 17, 1996, with respect
to the consolidated financial statements and schedules of
BioWhittaker, Inc. included in the Annual Report (Form 10-K)
for the year ended October 31, 1995.

                                  /s/ ERNST & YOUNG LLP
                                  Ernst & Young LLP

Baltimore, Maryland
September 5, 1996.




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