BIOTRANSPLANT INC
SC 13G/A, 2000-02-10
PHARMACEUTICAL PREPARATIONS
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<PAGE>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                               (Amendment No. 1)*

                           BIOTRANSPLANT INCORPORATED
                           --------------------------
                                (Name of Issuer)

                          Common Stock, $.01 par value
                         ------------------------------
                         (Title of Class of Securities)

                                     09066Y
                                 --------------
                                 (CUSIP Number)

                                December 31, 1999
             -------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

            / / Rule 13d-1(b)
            /X/ Rule 13d-1(c)
            / / Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 (the "Act") or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, SEE the
NOTES).


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                                  SCHEDULE 13G

CUSIP NO.     09066Y                                    Page   2   of   5  Pages
- --------------------------------------------------------------------------------
      NAMES OF REPORTING PERSONS
1.     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Joseph A. Cohen
- --------------------------------------------------------------------------------
      CHECK THE APPROPRIATE BOX IF MEMBER OF A GROUP*       (a)/_/
2.                                                          (b)/X/
- --------------------------------------------------------------------------------
      SEC USE ONLY
3.
- --------------------------------------------------------------------------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
4.
      USA
- --------------------------------------------------------------------------------


                               SOLE VOTING POWER
    NUMBER OF        5.
     SHARES                    417,491
  BENEFICIALLY       -----------------------------------------------------------
    OWNED BY                   SHARED VOTING POWER
      EACH           6.
   REPORTING                   71,250
     PERSON          -----------------------------------------------------------
      WITH                     SOLE DISPOSITIVE POWER
                     7.
                               417,491
                     -----------------------------------------------------------
                               SHARED DISPOSITIVE POWER
                     8.
                               71,250
- --------------------------------------------------------------------------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9.
      488,741
- --------------------------------------------------------------------------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  /_/
10.
- --------------------------------------------------------------------------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11.
      5.69%
- --------------------------------------------------------------------------------
      TYPE OF REPORTING PERSON*
12.
      IN
- --------------------------------------------------------------------------------

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>

Item 1(a).  Name of Issuer:

            Biotransplant Incorporated
            --------------------------------------------------------------------

ITEM 1(b).  ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICE:

            Charlestown Navy Yard, Building 75 Third Avenue, Charlestown, MA
            02129
            --------------------------------------------------------------------

ITEM 2(a).  NAME OF PERSON FILING:

            Joseph a. Cohen
            --------------------------------------------------------------------

ITEM 2(b).  ADDRESS OF PRINCIPAL BUSINESS OFFICE, OR IF NONE, RESIDENCE:

            c/o The Garnet Group, Inc., 825 Third Avenue, 40Th Floor, New York,
            NY 10022
            --------------------------------------------------------------------

ITEM 2(c).  CITIZENSHIP:

            United States
            --------------------------------------------------------------------

ITEM 2(d).  TITLE OF CLASS OF SECURITIES:

            Common Stock, $.01 par value
            --------------------------------------------------------------------

ITEM 2(e).  CUSIP NUMBER:

            09066Y
            --------------------------------------------------------------------

ITEM 3.     This Statement is filed pursuant to Rule 13d-1(c) of the Securities
            Exchange Act of 1934.

ITEM 4.     OWNERSHIP.

            Provide the following information regarding the aggregate
            number and percentage of the class of securities of the issuer
            identified in Item 1.

ITEM 4(a).  AMOUNT BENEFICIALLY OWNED:

            488,741
            --------------------------------------------------------------------

ITEM 4(b).  PERCENT OF CLASS:

            5.69%
            --------------------------------------------------------------------


                                   PAGE 3 OF 5
<PAGE>

ITEM 4(c).  NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS:

          (i)   Sole power to vote or to direct the vote: 417,491
                                                          ----------------------

          (ii)  Shared power to vote or to direct the vote: 71,250
                                                            --------------------

          (iii) Sole power to dispose or to direct the disposition of: 417,491
                                                                       ---------

          (iv)  Shared power to dispose or to direct the disposition of: 71,250
                                                                         -------

ITEM 5.     OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

            Not Applicable.
            --------------------------------------------------------------------

ITEM 6.     OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

            Not Applicable.
            --------------------------------------------------------------------

ITEM 7.     IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
            THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.

            Not Applicable.
            --------------------------------------------------------------------

ITEM 8.     IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

            Not Applicable.
            --------------------------------------------------------------------

ITEM 9.     NOTICE OF DISSOLUTION OF GROUP.

            Not Applicable.
            --------------------------------------------------------------------

ITEM 10.    CERTIFICATIONS.

            By signing below I certify that, to the best of my knowledge
            and belief, the securities referred to above were not acquired
            and are not held for the purpose of or with the effect of
            changing or influencing the control of the issuer of the
            securities and were not acquired and are not held in
            connection with or as a participant in any transaction having
            that purpose or effect.



                                   PAGE 4 OF 5
<PAGE>


                                    SIGNATURE

              After reasonable inquiry and to the best of my knowledge and
belief, the undersigned certifies that the information set forth in this
statement is true, complete and correct.

Dated:    February 8, 2000



                                               /s/ Joseph A. Cohen
                                               ---------------------------------
          Joseph A. Cohen



                                   PAGE 5 OF 5


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