DENDRITE INTERNATIONAL INC
S-3, 1999-11-22
PREPACKAGED SOFTWARE
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    AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON NOVEMBER 22, 1999
                                                      REGISTRATION NO. 333-_____
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                   ----------

                                    FORM S-3
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                                   ----------

                          DENDRITE INTERNATIONAL, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

                 NEW JERSEY                       22-2786386
       (STATE OR OTHER JURISDICTION OF        (I.R.S. EMPLOYER
        INCORPORATION OR ORGANIZATION)       IDENTIFICATION NUMBER)

                             1200 MT. KEMBLE AVENUE
                        MORRISTOWN, NEW JERSEY 07960-6797
                                 (973) 425-1200
          (ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING
            AREA CODE, OF REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)

                                   ----------

                              CHRISTOPHER J. FRENCH
                  VICE PRESIDENT, GENERAL COUNSEL AND SECRETARY
                             1200 MT. KEMBLE AVENUE
                          MORRISTOWN, NEW JERSEY 07960
                                 (973) 425-1200
            (NAME, ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER,
                   INCLUDING AREA CODE, OF AGENT FOR SERVICE)

                                   ----------

   APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: At such time
or  times  as  may  be  determined  by  the  selling   stockholders  after  this
registration statement becomes effective.

   If the only  securities  being  registered  on this  Form are  being  offered
pursuant to dividend or interest  reinvestment plans, please check the following
box. [_]

   If any of the securities being registered on this Form are to be registered
on a delayed or continuous basis pursuant to Rule 415 under the Securities Act
of 1933, check the following box. [X]

   If this  Form is filed to  register  additional  securities  for an  offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [_]

   If this Form is a  post-effective  amendment  filed  pursuant  to Rule 462(c)
under the  Securities  Act,  check the following box and list the Securities Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [_]

   If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. [_]
<PAGE>


<TABLE>
<CAPTION>
                               CALCULATION OF REGISTRATION FEE
==========================================================================================================
       TITLE OF                                 PROPOSED MAXIMUM   PROPOSED MAXIMUM
       SHARES TO                AMOUNT TO BE     OFFERING PRICE   AGGREGATE OFFERING      AMOUNT OF
    BE REGISTERED                REGISTERED       PER UNIT (1)        PRICE (1)        REGISTRATION FEE
==========================================================================================================
<S>                              <C>                 <C>             <C>                   <C>
Common Stock, no par value       2,351,354           $33.00          $77,594,682           $21,571
==========================================================================================================
<FN>
(1)  Estimated in accordance with Rule 457(c) under the Securities Act of 1933 solely for purposes of
     calculating the registration fee (based on the average of the high and low prices of Registrant's
     Common Stock as reported on the Nasdaq National Market on November 15, 1999).
</FN>
</TABLE>

THE REGISTRANT HEREBY AMENDS THIS  REGISTRATION  STATEMENT ON SUCH DATE OR DATES
AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT  SHALL FILE
A FURTHER AMENDMENT WHICH SPECIFICALLY  STATES THAT THIS REGISTRATION  STATEMENT
SHALL  THEREAFTER  BECOME  EFFECTIVE  IN  ACCORDANCE  WITH  SECTION  8(a) OF THE
SECURITIES  ACT OF  1933 OR  UNTIL  THIS  REGISTRATION  STATEMENT  SHALL  BECOME
EFFECTIVE  ON SUCH  DATE  AS THE  SECURITIES  AND  EXCHANGE  COMMISSION,  ACTING
PURSUANT TO SAID SECTION 8(a), MAY DETERMINE.
================================================================================


<PAGE>


RED HERRING TEXT

THE  INFORMATION  IN THIS  PRELIMINARY  PROSPECTUS  IS NOT  COMPLETE  AND MAY BE
CHANGED. THESE SECURITIES MAY NOT BE SOLD UNTIL THE REGISTRATION STATEMENT FILED
WITH THE  SECURITIES  AND EXCHANGE  COMMISSION  IS EFFECTIVE.  THIS  PRELIMINARY
PROSPECTUS  IS NOT AN OFFER  TO SELL  NOR  DOES IT SEEK AN  OFFER  TO BUY  THESE
SECURITIES IN ANY JURISDICTION WHERE THE OFFER OR SALE IS NOT PERMITTED.






<PAGE>

                 Subject to Completion. Dated November 22, 1999.

                                2,351,354 SHARES


                          DENDRITE INTERNATIONAL, INC.

                                  COMMON STOCK

                                   ----------

   This prospectus  relates to an offering of up to 2,351,354  shares by certain
selling  stockholders  identified  in this  prospectus.  We will not receive any
proceeds from the sale of these shares.

   Each of the selling  stockholders  has advised us that he or she  proposes to
offer the shares from time to time and in any of several different ways. Each of
the selling stockholders may offer shares in one or more of the following ways:

     o    through brokers or other agents,

     o    to underwriters or dealers,

     o    directly to one or more purchasers and

     o    by a combination of these methods of sale.

   The  selling  shareholders  and any  underwriters,  broker-dealers  or agents
participating  in the distribution of the shares of common stock covered by this
prospectus  may  be  deemed  to be  "underwriters"  within  the  meaning  of the
Securities  Act of 1933,  and any  profit on the sale of the  securities  by the
selling  shareholders and any discounts or commissions  received by any of those
underwriters,  broker-dealers  or  agents  may  be  deemed  to  be  underwriting
commissions under the Securities Act of 1933. To the extent required,  the names
of any  underwriter  and  applicable  commissions  or  discounts  and any  other
required information with respect to any particular sale will be set forth in an
accompanying  prospectus  supplement.  See "Plan of Distribution"  for a further
description of how the selling stockholders may dispose of the shares covered by
this prospectus.

   The common  stock is quoted in the Nasdaq  National  Market  System under the
symbol "DRTE".  The last reported sale price of the common stock on November 19,
1999 was $33.38 per share.

   See "Risk  Factors"  beginning  on page 3 to read about  certain  factors you
should consider before buying shares of the common stock.

                                   ----------

   NEITHER THE SECURITIES AND EXCHANGE  COMMISSION NOR ANY OTHER REGULATORY BODY
HAS APPROVED OR DISAPPROVED  OF THESE  SECURITIES OR PASSED UPON THE ACCURACY OR
ADEQUACY OF THIS PROSPECTUS.  ANY  REPRESENTATION  TO THE CONTRARY IS A CRIMINAL
OFFENSE.

                                   ----------

   NO DEALER,  SALESPERSON OR OTHER PERSON IS AUTHORIZED TO GIVE ANY INFORMATION
OR TO REPRESENT ANYTHING NOT CONTAINED IN THIS PROSPECTUS.  YOU MUST NOT RELY ON
ANY UNAUTHORIZED INFORMATION OR REPRESENTATIONS.  THIS PROSPECTUS IS AN OFFER TO
SELL OR TO BUY  ONLY THE  SHARES  OFFERED  BY THIS  PROSPECTUS,  BUT ONLY  UNDER
CIRCUMSTANCES AND IN JURISDICTIONS  WHERE IT IS LAWFUL TO DO SO. THE INFORMATION
CONTAINED IN THIS PROSPECTUS IS CURRENT ONLY TO THE DATE BELOW.

                                   ----------

                            Prospectus dated   , 1999.


<PAGE>


                                TABLE OF CONTENTS

                                                                            PAGE
                                                                            ----

FORWARD-LOOKING STATEMENTS ................................................    2
DENDRITE INTERNATIONAL, INC................................................    3
RISK FACTORS ..............................................................    3
WHERE YOU CAN FIND MORE INFORMATION .......................................    8
SELLING STOCKHOLDERS ......................................................   10
PLAN OF DISTRIBUTION ......................................................   11
USE OF PROCEEDS ...........................................................   12
VALIDITY OF COMMON STOCK ..................................................   12
EXPERTS ...................................................................   13


                           FORWARD-LOOKING STATEMENTS

   This prospectus contains certain  forward-looking  statements that we believe
are within the meaning of Section 27A of the  Securities Act of 1933, as amended
(the "Securities Act") and Section 21-E of the Securities  Exchange Act of 1934,
as amended (the  "Exchange  Act"),  which are intended to be covered by the safe
harbors  created  thereby.  For  this  purpose,  any  statements  that  are  not
statements of historical  fact may be deemed to be  forward-looking  statements.
Those   statements  in  this   prospectus   containing  the  words   "believes",
"anticipates",   "plans",   "expects"   and   similar   expressions   constitute
forward-looking statements,  although not all forward-looking statements contain
such  identifying  words.  These  forward-looking  statements  are  based on our
current expectations,  assumptions,  estimates and projections about our company
and  the   pharmaceutical   and  consumer   packaged   goods   industries.   All
forward-looking  statements  involve risks and  uncertainties,  including  those
risks  identified  under "Risk  Factors",  many of which are beyond our control.
Although  we  believe  that  the  assumptions   underlying  our  forward-looking
statements are reasonable, any of the assumptions could be inaccurate and actual
results  may  differ  from those  indicated  by the  forward-looking  statements
included in this  prospectus,  as more fully described under "Risk Factors".  In
the  light of the  significant  uncertainties  inherent  in the  forward-looking
statements included in this prospectus, you should not consider the inclusion of
such information as a  representation  by us or anyone else that we will achieve
our  objectives  and plans.  Moreover,  we assume no  obligation to update these
forward-looking  statements to reflect actual results, changes in assumptions or
changes in other factors affecting such factor-looking statements.


                                      -2-
<PAGE>



                          DENDRITE INTERNATIONAL, INC.

         We are a leading worldwide  supplier of a comprehensive  range of sales
force software products and support services to the pharmaceutical  industry. We
also supply our solutions to manufacturers of consumer  packaged goods (that is,
branded, non-durable goods used by individual consumers).

         Our  executive   offices  are  located  at  1200  Mt.  Kemble   Avenue,
Morristown, N.J. 07960-6797. Our telephone number is (973) 425-1200.


                                  RISK FACTORS

        OUR BUSINESS IS HEAVILY DEPENDENT ON THE PHARMACEUTICAL INDUSTRY

         Most of our sales force  software  products  and support  services  are
currently  used in connection  with the marketing and sale of  prescription-only
drugs. This market is undergoing a number of significant changes. These include:

          o    consolidations  and  mergers  which may  reduce the number of our
               existing and potential customers;

          o    reclassification  of formerly  prescription-only  drugs to permit
               their over-the-counter sale;

          o    competitive  pressures on our pharmaceutical  customers resulting
               from the  continuing  shift to  delivery  of  healthcare  through
               managed care organizations; and

          o    changes in law, such as government  mandated price reductions for
               prescription-only  drugs,  that affect the healthcare  systems in
               countries  where  our  customers  and  potential   customers  are
               located.

         We cannot assure you that we can respond  effectively  to any or all of
these and other  changes in the  marketplace.  Our failure to do so could have a
material  adverse  effect  on  our  business,  operating  results  or  financial
condition.

                OUR QUARTERLY RESULTS OF OPERATIONS MAY FLUCTUATE
               SIGNIFICANTLY AND MAY NOT MEET MARKET EXPECTATIONS

         Our  results of  operations  may vary from  quarter  to quarter  due to
lengthy sales and implementation cycles for our products,  our fixed expenses in
relation to our  fluctuating  revenues and variations in our  customers'  budget
cycles,  each of which is discussed  below. As a result,  you should not rely on
quarter-to-quarter  comparisons of our results of operations as an indication of
future  performance.  It is possible  that in some future  period our results of
operations  may be below the  expectations  of the public  market  analysts  and
investors. If this happens, the price of our common stock may decline.

          o    Our lengthy sales and implementation  cycles make it difficult to
               predict our  quarterly  revenues.  The selection of a sales force
               software  product  often  entails  an  extended   decision-making
               process  because of the strategic  implications  and  substantial
               costs associated with a customer's license of the software. Given
               the importance of the decision, senior levels of management often
               are involved and, in some  instances,  the board of directors may
               be involved in this  process.  As a result,  the  decision-making
               process for some of our larger  customers  can take six to twelve
               months,   although  in  some  cases  it  may  take  even  longer.
               Accordingly,  we cannot  control  or  predict  the  timing of our
               execution of contracts with customers.

               In  addition,   for  customers   with  large  sales  forces,   an
               implementation process of three to six months is customary before
               the software is rolled out to a customer's sales force.  However,
               if a customer were to



                                      -3-
<PAGE>

               delay  or  extend  its  implementation   process,  our  quarterly
               revenues may decline below  expected  levels and could  adversely
               affect our results of operations.

          o    Our  fixed  costs  may  lead  to  fluctuations  in our  quarterly
               operating  results  if  revenues  fall  below  expectations.   We
               establish our expenditure levels for product  development,  sales
               and marketing and some of our other  operating  expenses based in
               large  part  on our  expected  future  revenues  and  anticipated
               competitive conditions. In particular, we frequently add staff in
               advance of new business to permit adequate time for training.  If
               the new business is  subsequently  delayed or  canceled,  we will
               have  incurred  expenses  without  the  associated   revenue.  In
               addition,  we  may  increase  sales  and  marketing  expenses  if
               competitive   pressures   become   greater   than  we   currently
               anticipate.  Since only a small  portion of our  expenses  varies
               directly  with our actual  revenues,  our  operating  results and
               profitability  are likely to be adversely and  disproportionately
               affected if our revenues fall below expectations.

          o    Our business is affected by variations in our  customers'  budget
               cycles. We have historically realized a greater percentage of our
               license fees and service  revenues in the second half of the year
               than in the first half because, among other things, our customers
               typically  spend more of their annual  budget  authorization  for
               sales force software  products and support services in the second
               half of the year. However,  the relationship  between the amounts
               spent in the  first and  second  halves of the year may vary from
               year to year and from customer to customer. In addition,  changes
               in our customers' budget  authorizations may reduce the amount of
               revenues we receive  from the license of  additional  software or
               the provision of additional services.  As a result, our operating
               results could be adversely affected.

              OUR REVENUES WOULD DECLINE AND OUR BUSINESS WOULD BE
             ADVERSELY AFFECTED BY THE LOSS OF ONE OF OUR CUSTOMERS

         We derive a significant  portion of our revenues from a limited  number
of  customers  (considering  all  affiliates  of each  customer  as part of that
customer).  Approximately  49% of our total  revenues  in 1998 came from our top
three customers.  Approximately  51% of our total revenues in 1997 came from our
top three customers.  Approximately  50% of our total revenues in 1996 came from
our top three customers. We believe that the costs to our customers of switching
to a competitor's  software product,  or of taking significant system management
functions in-house,  are substantial.  Nevertheless,  some of our customers have
switched,  and in the future other  customers may switch,  to software  products
and/or services offered by our  competitors.  If any of our major customers were
to make such a change,  our business,  operating results or financial  condition
would be materially and adversely affected.

             WE MAY BE UNABLE TO SUCCESSFULLY INTRODUCE NEW PRODUCTS
                       OR RESPOND TO TECHNOLOGICAL CHANGE

         The market for sales force software products changes rapidly because of
frequent  improvements in computer hardware and software technology.  Our future
success will depend, in part, on our ability to:

          o    use  available  technologies  and data  sources  to  develop  new
               products  and  services  and to enhance our current  products and
               services;

          o    introduce new solutions that keep pace with  developments  in our
               target markets; and

          o    address the changing and increasingly  sophisticated needs of our
               customers.

         We cannot assure you that we will  successfully  develop and market new
products or product  enhancements that respond to technological  advances in the
marketplace,  or that we will do so in a timely  fashion.  We also cannot assure
you that our products will adequately and competitively address the needs of the
changing marketplace.




                                      -4-
<PAGE>

         Competition for software products has been  characterized by shortening
product cycles. We may be materially and adversely affected by this trend if the
product cycles for our products prove to be shorter than we anticipate.  If that
happens,  our  business,  operating  results  or  financial  condition  could be
adversely affected.

         To remain  competitive and to continue to develop and enhance  products
acquired as part of our recent  acquisitions,  we also may have to spend more of
our revenues on product  research and development than we have in the past. As a
result, our results of operations could be materially and adversely affected.

         Further,  our  software  products are  technologically  complex and may
contain previously  undetected errors or failures.  Such errors have occurred in
the past and we cannot  assure you that,  despite our testing,  our new products
will be free from  errors.  Errors that result in losses or delays  could have a
material  adverse  effect  on  our  business,  operating  results  or  financial
condition.

             WE ARE EXPOSED TO RISKS ASSOCIATED WITH THE YEAR 2000--
                         YEAR 2000 READINESS DISCLOSURE

DEMAND FOR OUR SOFTWARE PRODUCTS AND SERVICES MAY DECLINE BEFORE
AND AFTER THE YEAR 2000

         A substantial amount of demand for our software may come from customers
in the process of replacing and upgrading  software  applications to accommodate
the change in date to the Year 2000.  This  demand may have  contributed  to our
1998  sales  growth  as well as our  1999  sales  growth.  Once  customers  have
completed these activities,  we may experience a deceleration in revenue growth.
In  addition,  the  expense  and time  associated  with  remediation  efforts by
customers to address Year 2000 compliance  problems for software  products other
than ours may cause our customers to delay the purchase of, or reduce the amount
they spend on, our products and services, both before and after January 1, 2000.
Such reductions could have a material adverse effect on our business,  operating
results or financial condition.

OUR YEAR 2000 REMEDIATION EFFORTS MAY NOT BE SUCCESSFUL

         As part  of the  Year  2000  compliance  plan,  we  have  assessed  the
readiness of our Internal Programs and Systems. We believe our Internal Programs
and  Systems are  substantially  Year 2000  compliant.  However,  if  additional
detects,  including  defects  in  hardware,  are  identified  and the  necessary
modifications  and  conversions  are not made,  or are not completed in a timely
manner,  the Year 2000  problem  could  have a  material  adverse  effect on our
business, operating results or financial condition.

WE MAY INCUR MATERIAL EXPENSES IN CONNECTION WITH ANY CLAIM RELATING TO
YEAR 2000 COMPLIANCE OF OUR OWN PRODUCTS OR THE PRODUCTS OF THIRD PARTIES

         We believe the sales force software products that we currently offer to
our customers,  prior to any customization,  are Year 2000 compliant.  We cannot
assure you, however,  that our current products do not contain undetected errors
or defects  associated with the Year 2000 date  functionality that may result in
material costs to us.

         Some of our  older  products  will  not,  and some may not,  accurately
process dates after  December 31, 1999. To the extent any of these  products are
still in use in 1999,  we will  continue to attempt to migrate our  customers to
products  that are Year  2000  compliant.  We cannot  assure  you that this will
occur.  A  failure  to  migrate  any  customer  to a  product  that is Year 2000
compliant could adversely  affect our business,  operating  results or financial
condition. We may also experience increased expenses which we cannot recoup from
current  customers in addressing  their  migration to software that is Year 2000
compliant.  We may also incur  additional  expenses  with  remediating  software
products of our current  customers,  including  those  customers of companies we
have recently acquired.



                                      -5-
<PAGE>

         In addition,  some of our customers may attempt to hold us  responsible
for Year 2000  compliance of hardware or software not supplied or created by us,
but used in  conjunction  with one or more of our  products.  For  example,  our
customers'  computer  hardware  and  software,  with  which  our  software  must
interface,  may not properly handle date information after the Year 2000 without
error or interruption.

              INCREASED COMPETITION MAY RESULT IN PRICE REDUCTIONS
               AND DECREASED DEMAND FOR OUR PRODUCTS AND SERVICES

         We believe there are  approximately ten other companies that sell sales
force software  products and specifically  target the  pharmaceutical  industry,
including:

          o    four  competitors  that are  actively  selling  in more  than one
               country; and

          o    three competitors that also offer sales force support services.

         We believe  that most of our  competitors  offer sales  force  software
products  and/or services that do not address the variety of customer needs that
our solutions address. However, these competing solutions may cost less than our
solutions. We also face competition from many vendors that market and sell sales
force software products in the consumer  packaged goods market. In addition,  we
also compete with various companies that provide support services similar to our
services.  We believe our ability to compete  depends on many  factors,  some of
which are beyond our control, including:

          o    the number and success of new market entrants supplying competing
               sales force products or support services;

          o    expansion  of  product  lines  and/or  service  offerings  by, or
               consolidation among, our existing competitors; and

          o    development  and/or  operation of in-house  sales force  software
               products or services by our customers and potential customers.

         Some of our  competitors  and potential  competitors  are part of large
corporate groups and have longer operating  histories and significantly  greater
financial,  sales,  marketing,  technology and other  resources than we have. We
cannot  assure  you  that we will be able to  compete  successfully  with  these
companies or that  competition  will not have a material  adverse  effect on our
business, operating results or financial condition.

          SOME OF OUR CUSTOMERS RELY ON OUR COMPETITORS FOR MARKET DATA

         Current  market data on the sales of  prescription-only  pharmaceutical
products is an important  element for the operation of our sales force  software
products in the  prescription-only  pharmaceutical  industry.  Our customers use
this data to guide and organize their sales forces and marketing  efforts.  Some
of the leading  purveyors  of this  market  information  compete  with us either
directly or through  affiliates  or may compete with us in the future.  If these
purveyors of market information  require  pharmaceutical  companies to use their
sales force  products  and/or  services,  our  business,  operating  results and
financial condition may be materially and adversely affected.

                     OUR INTERNATIONAL OPERATIONS HAVE RISKS
                       THAT OUR DOMESTIC OPERATIONS DO NOT

         The sale of our  products and  services in foreign  countries  accounts
for,  and is  expected  in the  future to account  for,  a material  part of our
revenues.  These sales are subject to risks inherent in  international  business
activities, including:



                                      -6-
<PAGE>

          o    any adverse change in the political or economic  environments  in
               these countries;

          o    economic instability;

          o   any adverse change in tax, tariff, trade or other regulations;

          o    the  absence  or  significant   lack  of  legal   protection  for
               intellectual property rights;

          o    exposure to exchange  rate risk for  service  revenues  which are
               denominated in currencies other than U.S. dollars; and

          o    difficulties  in managing  an  organization  spread over  various
               jurisdictions.

           OUR SUCCESS DEPENDS ON RETAINING OUR KEY SENIOR MANAGEMENT
            TEAM AND ON ATTRACTING AND RETAINING QUALIFIED PERSONNEL

         Our  future  success  depends,   to  a  significant  extent,  upon  the
contributions  of our executive  officers and key sales,  technical and customer
service personnel.  Our future success also depends on our continuing ability to
attract  and  retain  highly  qualified  technical  and  managerial   personnel.
Competition  for  such  personnel  is  intense.  We  have at  times  experienced
difficulties  in  recruiting  qualified  personnel  and we may  experience  such
difficulties in the future.  Any such  difficulties  could adversely  affect our
business, operating results or financial condition.

     OUR INABILITY TO MANAGE OUR GROWTH COULD ADVERSELY AFFECT OUR BUSINESS

         To manage our growth  effectively,  we must  continue to  strength  our
operational,  financial and management information systems and expand, train and
manage our work force.  However, we may not be able to do so effectively or on a
timely  basis.  Failure to do so could have a material  adverse  effect upon our
business, operating results or financial condition.

         In addition,  we have historically  pursued and will continue to pursue
acquisitions  of companies with  complimentary  businesses or products.  We also
have  entered  and will  continue to enter into  strategic  joint  ventures  and
alliances. There can be no assurance,  however, that we will be able to identify
attractive  opportunities or enter into any such  transactions in the future. In
addition, as to completed  acquisitions,  there can be no assurance that we will
be able to integrate successfully the acquired entity into our operations. Among
other things, specific risks associated with such acquisitions include:

          o    possible adverse effects on the Company's operating results;

          o    diversion of management's attention;

          o    unanticipated    liabilities    or    contingencies,    including
               unanticipated liabilities associated with Year 2000 compliance of
               acquired companies and their customers; and

          o    possible inability to integrate service offerings, operations and
               employees of acquired businesses.

               OUR BUSINESS DEPENDS ON PROPRIETARY TECHNOLOGY THAT
                    WE MAY NOT BE ABLE TO PROTECT COMPLETELY

         We rely on a combination of trade secret, copyright and trademark laws,
non-disclosure  and other  contractual  agreements  and  technical  measures  to
protect our proprietary technology.  We cannot assure you that the steps we take
will prevent misappropriation of this technology. Further, protective actions we
have  taken  or  will  take  in the  future  may not



                                      -7-
<PAGE>

prevent  competitors  from  developing  products  with  features  similar to our
products.  In addition,  effective  copyright and trade secret protection may be
unavailable or limited in certain foreign  countries.  We have, on occasion,  in
response to a request by our customer,  entered into agreements which require us
to place  our  source  code in  escrow to secure  our  service  and  maintenance
obligations.

         Further,  we believe that our products and  trademarks  do not infringe
upon the proprietary rights of third parties.  However, third parties may assert
infringement  claims  against us in the future that may result in the imposition
of damages or  injunctive  relief  against us. In addition,  any such claims may
require  us to enter  into  royalty  arrangements.  Any of these  results  could
materially  and adversely  affect our business,  operating  results or financial
condition.

          UNIQUE CHARACTERISTICS OF THE CONSUMER PACKAGED GOODS MARKET

         We market and sell sales force software  products and support  services
to companies in the consumer packaged goods market.  The selling  environment in
this  market  has  unique   characteristics   that  differentiate  it  from  the
pharmaceutical  market. In addition, we believe that the consumer packaged goods
market  is   composed   of   sub-markets,   each  of  which   may  have   unique
characteristics.  Accordingly,  we  cannot  assure  you  that we will be able to
replicate  in  this  market  the  success  we  have   achieved  in  the  ethical
pharmaceutical market.

             PROVISIONS OF OUR CHARTER DOCUMENTS AND NEW JERSEY LAW
                    MAY DISCOURAGE AN ACQUISITION OF DENDRITE

         Provisions of our Restated  Certificate of  Incorporation,  our By-laws
and New Jersey law may make it more  difficult  for a third party to acquire us.
For  example,   the  board  of  directors  may,   without  the  consent  of  the
stockholders,  issue  preferred  stock with rights senior to those of the common
stock.

              OUR COMMON STOCK MAY BE SUBJECT TO PRICE FLUCTUATIONS

         The market price of our common stock may be  significantly  affected by
the following factors:

          o    the announcement or the introduction of new products by us or our
               competitors;

          o    quarter-to-quarter   variations  in  our  operating  results  and
               changes in earnings estimates by analysts;

          o    market conditions in the technology,  healthcare and other growth
               sectors; and

          o    general  consolidation  in the  healthcare  information  industry
               which may result in the market  perceiving us or other comparable
               companies as potential acquisition targets.

         Further, the stock market has experienced on occasion extreme price and
volume  fluctuations.  The  market  prices  of the  equity  securities  of  many
technology companies have been especially volatile and often have been unrelated
to the operating performance of such companies.  These broad market fluctuations
may have a material adverse effect on the market price of our common stock.


                       WHERE YOU CAN FIND MORE INFORMATION

                              AVAILABLE INFORMATION

         We are subject to the  informational  requirements of the Exchange Act,
and,  in  accordance  therewith,   file  reports,  proxy  statements  and  other
information with the Commission. You may read and copy all or any portion of the
Registration



                                      -8-
<PAGE>

Statement  or any  reports,  statements  or  other  information  we  file at the
Commission's  Public  Reference  Room at 450  Fifth  Street,  N.W.,  Room  1024,
Judiciary Plaza,  Washington,  D.C. 20549, as well as the Commission's  Regional
Offices  at 7 World  Trade  Center,  Suite  1300,  New York,  New York 10045 and
Citicorp Center, 500 West Madison Street,  Suite 1400, Chicago,  Illinois 60611.
You can request copies of these documents, upon payment of a duplicating fee, by
writing to the  Commission.  Please call the  Commission at  1-800-SEC-0330  for
further  information  on  the  operation  of the  Public  Reference  Rooms.  Our
Commission filings,  including the Registration Statement, are also available to
you on the Commission  Internet site  (http://www.sec.gov).  Our common stock is
quoted on the Nasdaq National Market.  Reports, proxy and information statements
and other  information  concerning  our  company  can also be  inspected  at the
National  Association  of  Securities  Dealers,  Inc.  at 1735 K  Street,  N.W.,
Washington,  D.C.  20006.  We will provide without charge to each person to whom
this prospectus has been delivered, upon written or oral request of such person,
a copy  (without  exhibits  other than  exhibits  specifically  incorporated  by
reference)  of  any  or  all  documents  incorporated  by  reference  into  this
prospectus.  Requests  for such copies  should be  directed  to 1200 Mt.  Kemble
Avenue,  Morristown,  New Jersey  07960-6797,  Attention:  Secretary,  telephone
number  (973)  425-1200.  We have  filed  with  the  Commission  a  Registration
Statement  on Form S-3  (including  all  amendments  and exhibits  thereto,  the
"Registration  Statement")  under the  Securities Act with respect to the common
stock  offered  hereby.  This  prospectus,  which  constitutes  a  part  of  the
Registration  Statement,  omits  certain  of the  information  contained  in the
Registration  Statement and the exhibits and schedules  thereto on file with the
Commission  pursuant to the Securities Act and the rules and  regulations of the
Commission  thereunder.  For further  information about us and our common stock,
reference is made to the  Registration  Statement and the exhibits and schedules
thereto.  Statements  contained in this prospectus regarding the contents of any
agreement or other  document filed as an exhibit to the  Registration  Statement
are not necessarily complete, and in each instance reference is made to the copy
of such agreement filed as an exhibit to the Registration  Statement,  each such
statement being qualified in all respects by such reference.

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The following documents filed by us with the Commission pursuant to the
Exchange Act are incorporated by reference herein and made a part hereof:

          o    Annual Report on Form 10-K for the fiscal year ended December 31,
               1998  (except for Items 6, 7 and 8, which have been  restated and
               superseded   as  a   result   of  the   acquisition   of   CorNet
               International,  Ltd.  by Items 5(b) and 5(c) of our June 30, 1999
               Quarterly  Report and which are  therefore  not  incorporated  by
               reference).

          o    Definitive  proxy  statement  dated  April  16, 1999 for the 1999
               Annual Meeting of Shareholders.

          o    Quarterly  Reports on Form 10-Q for the  quarterly  periods ended
               March 31, 1998,  June 30, 1999 and  September  30, 1999 (our June
               30,  1999  Quarterly   Report   includes  a  restatement  of  our
               consolidated  financial  statements  as of December  31, 1997 and
               1998 and for each of the three years in the period ended December
               31,  1998,   restated  to  reflect  the   acquisition  of  CorNet
               International, Ltd.).

          o    Current  Report on Form 8-K, filed with the Commission on June 2,
               1999.

          o    The  description  of our common stock  contained in  registration
               statement  on  Form  S-3  (File  No.  333-71337),  including  any
               amendment or report filed with the  Commission for the purpose of
               updating the description.

<PAGE>

         All documents we have filed pursuant to Sections  13(a),  13(c),  14 or
15(d) of the Exchange Act subsequent to the date of the  Registration  Statement
of which  this  prospectus  forms a part and  prior  to the  termination  of the
offering  of the  common  stock  made  hereby  shall be deemed  incorporated  by
reference in this  prospectus and to be a part hereof from the date of filing of
such documents.  Any statement contained in a document incorporated or deemed to
be incorporated herein by reference,  or contained in this prospectus,  shall be
deemed to be modified or  superseded  for  purposes  of this  prospectus  to the
extent  that a statement  contained  herein or in any other  subsequently  filed
document  which  also is or is deemed to be

                                      -9-
<PAGE>

incorporated by reference herein modifies or supersedes such statement. Any such
statement so modified or superseded  shall not be deemed,  except as so modified
or superseded, to constitute a part of this prospectus.




                                      -10-
<PAGE>


                              SELLING STOCKHOLDERS

         The table below sets forth the beneficial ownership of our common stock
by the selling  stockholders as of the date of this prospectus and following the
sale of shares of common stock offered hereby.  Except as indicated herein,  and
as provided by  applicable  community  property  laws,  the persons named in the
table have sole voting and investment power with respect to all shares of common
stock.

         The  applicable  percentage  of ownership  prior to  completion  of the
offering  is based on  38,386,002  shares  of  common  stock  outstanding  as of
September  30,  1999,  as adjusted to reflect the 3 for 2 stock split  effective
October 8, 1999.

         Beneficial  ownership is determined in accordance with the rules of the
Securities  and  Exchange  Commission  (the   "Commission").   For  purposes  of
calculating  beneficial  ownership,  common stock  subject to options  currently
exercisable  or  exercisable  on or  prior  to 60 days  after  the  date of this
prospectus are deemed outstanding for computing the percentage  ownership of the
person holding such options,  but are not deemed  outstanding  for computing the
percentage ownership of any other person.

         Mr. De Pelsmaeker has been a general manager for Dendrite Belgium S.A.,
a  subsidiary  of  Dendrite,  since  July 1998.  The  remainder  of the  selling
shareholders acquired their shares as a result of our acquisition in 1999 of all
outstanding  stock  of  CorNet  International,  Ltd.  and  Marketing  Management
International;  while Messrs.  Revitt,  Berry and  Rennekamp  and Mss.  Patricia
Kennedy, Dehaven and Shoemaker are officers or employees of SalesPlus/CorNet,  a
subsidiary  of  Dendrite,  none of the  selling  shareholders  other than Mr. De
Pelsmaeker have continuing any material relationship with us.

<TABLE>
<CAPTION>
                               SHARES BENEFICIALLY OWNED                      SHARES BENEFICIALLY OWNED
                                    BEFORE OFFERING              NUMBER OF         AFTER OFFERING
                               -------------------------         SHARES TO    -------------------------
NAME OF SELLING STOCKHOLDER    NUMBER     PERCENTAGE             BE OFFERED     NUMBER     PERCENTAGE
- ---------------------------    ------     ----------             ----------     ------     ----------

<S>                              <C>          <C>                 <C>           <C>           <C>
Geert De Pelsmaeker              71,076         *                  51,076       20,000          *
MMI Holdings Inc.               158,490         *                  79,245       79,245          *
Kendryx Enterprises LP          753,924       1.96%               753,924          0            *
John B. Kennedy                 679,699       1.77%               679,699          0            *
Bernard F. Kennedy              206,718         *                 206,718          0            *
Deborah Lancaster               206,718         *                 206,718          0            *
Patricia H. Kennedy              74,225         *                  74,225          0            *
Peter A. Reckert                 63,999         *                  63,999          0            *
Christopher Koehler              53,333         *                  53,333          0            *
Peter Fenner                     42,666         *                  42,666          0            *
Sean Kennedy                     36,913         *                  36,913          0            *
Kevin B. Kennedy                 36,913         *                  36,913          0            *
Frank C. Revitt                  21,767         *                  21,767          0            *
Matthew Berry                    10,667         *                  10,667          0            *
Hilda J. Hendryx                  5,596         *                   5,596          0            *
William Kennedy                   3,819         *                   3,819          0            *
Arthur J. Kennedy                 3,819         *                   3,819          0            *
Madelaine Gardner                 3,819         *                   3,819          0            *
Susan H. Hendryx                  3,819         *                   3,819          0            *
Susan Coursen                     1,984         *                   1,984          0            *
Morris Noretsky                   1,778         *                   1,778          0            *
Kim Wyler                         1,717         *                   1,717          0            *
Shelly M. Dehaven                 1,511         *                   1,511          0            *
Maria Alessi                      1,127         *                   1,127          0            *
Gerard Rennekamp                    860         *                     860          0            *
David Escalante                     711         *                     711          0            *
Johanna Shoemaker                   711         *                     711          0            *
Regina Killian                      533         *                     533          0            *
Shane Waters                        412         *                     412          0            *
Jay Haines                          356         *                     356          0            *
Asif Rajwani                        356         *                     356          0            *
Cheryl Tutrone                      356         *                     356          0            *
<FN>
*    Less than 1% of the outstanding shares of common stock.
</FN>
</TABLE>

                                      -11-
<PAGE>


                              PLAN OF DISTRIBUTION

         The selling  shareholders  and their pledgees,  donees,  transferees or
other  successors in interest may offer and sell, from time to time, some or all
of the shares of common stock covered by this prospectus. We have registered the
shares of common  stock  covered  by this  prospectus  for offer and sale by the
selling  shareholders  so that those  shares may be freely sold to the public by
them. Registration of the shares of common stock covered by this prospectus does
not mean,  however,  that those shares  necessarily  will be offered or sold. We
will not receive any proceeds from any sale by the selling  shareholders  of the
securities.  We will pay all costs,  expenses  and fees in  connection  with the
registration of those shares of common stock,  including fees of our counsel and
accountants,  fees payable to the  Commission,  listing fees, and the reasonable
fees and  disbursements  of one law firm  selected  as counsel  for the  selling
shareholders  in connection  with the  registration.  We estimate those fees and
expenses to be  approximately  $60,000.  The selling  shareholders  will pay all
underwriting  discounts and commissions and similar  selling  expenses,  if any,
attributable  to the  sale  of the  shares  of  common  stock  covered  by  this
prospectus.

         The selling shareholders, including their pledgees, donees, transferees
or other successors in interest,  may sell the shares of common stock covered by
this  prospectus  from time to time at market  prices  prevailing at the time of
sale, at prices related to market prices,  at a fixed price or prices subject to
change or at negotiated prices, by a variety of methods including the following:

          o    in privately negotiated transactions;

          o    through broker-dealers, who may act as agents or principals;

          o    in a block trade in which a broker-dealer  will attempt to sell a
               block of  shares of common  stock as agent but may  position  and
               resell a portion  of the block as  principal  to  facilitate  the
               transaction;

          o    through  one  or  more  underwriters  on  a  firm  commitment  or
               best-efforts basis;

          o    directly to one or more purchasers;

          o    through agents;

          o    through option transactions,  forward contracts,  equity swaps or
               other derivative transactions relating to the securities;

          o    through short sales of the securities; and

          o    in any combination of the above.

         As described  above,  the selling  shareholders  may enter into hedging
transactions with broker-dealers or other financial institutions.  In connection
with such  transactions,  broker-dealers  or other  financial  institutions  may
engage in short sales of our common stock in the course of hedging the positions
they assume with the selling  shareholders.  The selling  shareholders  may also
enter into options or other transactions with  broker-dealers or other financial
institutions which require the delivery to such broker-dealer or other financial
institution of shares of common stock covered by this  prospectus,  which shares
such  broker-dealer  or other financial  institution may resell pursuant to this
prospectus (as supplemented or amended to reflect such transaction).

         In  effecting  sales,   brokers  or  dealers  engaged  by  the  selling
shareholders   may  arrange  for  other  brokers  or  dealers  to   participate.
Broker-dealer transactions may include:


                                      -12-
<PAGE>

          o    purchases  of the shares of common  stock by a  broker-dealer  as
               principal  and  resales  of the  shares  of  common  stock by the
               broker-dealer for its account pursuant to this prospectus;

          o    ordinary brokerage transactions; or

          o    transactions in which the broker-dealer solicits purchasers.

         At any time a particular offer of the shares of common stock covered by
this  prospectus  is made, a revised  prospectus or  prospectus  supplement,  if
required,  will be  distributed  which  will set forth the  aggregate  amount of
shares of common stock covered by this prospectus being offered and the terms of
the offering, including the name or names of any underwriters,  dealers, brokers
or agents, any discounts, commissions,  concessions and other items constituting
compensation  from the selling  shareholders  and any discounts,  commissions or
concessions allowed or reallowed or paid to dealers. Such prospectus supplement,
and, if necessary,  a post-effective  amendment to the registration statement of
which this  prospectus is a part,  will be filed with the  Commission to reflect
the disclosure of additional information with respect to the distribution of the
shares of common stock covered by this prospectus.

         In  connection  with the sale of the shares of common stock  covered by
this prospectus through underwriters,  underwriters will receive compensation in
the  form  of  underwriting  discounts  or  commissions  and  may  also  receive
commissions  from  purchasers of shares of common stock for whom they may act as
agent. Underwriters may sell to or through dealers, and such dealers may receive
compensation  in the form of  discounts,  concessions  or  commissions  from the
underwriters  and/or  commissions  from the  purchasers for whom they may act as
agent.

         The common stock is quoted in the NASDAQ  National  Market System under
the symbol "DRTE".

         The selling shareholders and any underwriters, broker-dealers or agents
participating  in the distribution of the shares of common stock covered by this
prospectus  may  be  deemed  to be  "underwriters"  within  the  meaning  of the
Securities  Act of 1933,  and any  profit on the sale of the  securities  by the
selling  shareholders and any discounts or commissions  received by any of those
underwriters,  broker-dealers  or  agents  may  be  deemed  to  be  underwriting
commissions under the Securities Act of 1933.

         We have agreed to indemnify the selling shareholders (other than Mr. De
Pelsmaeker and MMI Holdings,  Inc.) and each person or entity which participates
as or may be  deemed  to be an  underwriter  in the  offering  or sale of  those
selling shareholders' shares of common stock against certain liabilities (and to
contribute to payments in respect of those liabilities),  including  liabilities
arising under the Securities Act of 1933. The selling  shareholders may agree to
indemnify any agent or broker-dealer that participates in transactions involving
offers or sales of the shares of common stock covered by this prospectus against
certain liabilities,  including  liabilities arising under the Securities Act of
1933.

         Some of the shares of common stock  covered by this  prospectus  may be
sold in private  transactions or under Rule 144 under the Securities Act of 1933
rather than pursuant to this prospectus.


                                 USE OF PROCEEDS

         We will not receive any proceeds from any sales of the shares.


                            VALIDITY OF COMMON STOCK

         The validity of the common  stock  offered  thereunder  has been passed
upon for us by Sullivan & Cromwell, New York, New York.



                                      -13-
<PAGE>

                                     EXPERTS

         Our consolidated  financial statements as of December 31, 1997 and 1998
and  for  each of the  three  years  in the  period  ended  December  31,  1998,
incorporated by reference in this  prospectus and elsewhere in the  Registration
Statement  have  been  audited  by  Arthur  Andersen  LLP,   independent  public
accountants, as indicated in their report with respect thereto, and are included
in this  prospectus  in reliance  upon the  authority of Arthur  Andersen LLP as
experts in giving these reports.

         The financial statements of CorNet  International,  Ltd. as of December
31, 1997 and 1998 and for each of the three years in the period  ended  December
31, 1998, are incorporated by reference herein and in the Registration Statement
in  reliance  upon  the  report  of  KPMG  LLP,  independent   certified  public
accountants,  incorporated by reference  herein,  and upon the authority of said
firm as experts in accounting and auditing.



                                      -14-
<PAGE>



                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

         The  following   are  the  estimated   expenses  of  the  issuance  and
distribution of the securities  being  registered,  all of which will be paid by
the Registrant.

                   Commission registration fee ...   $20,467
                   Nasdaq National Market fee ....         0
                   Printing and engraving expenses         0
                   Legal fees and expenses .......   $38,000
                   Miscellaneous .................   $ 1,533
                        Total ....................   $60,000

ITEM 15.  INDEMNIFICATION OF OFFICERS AND DIRECTORS

         Section  14A:3-5  of the  New  Jersey  Business  Corporation  Act  (the
"NJBCA")  gives the  Registrant  power to indemnify  each of its  directors  and
officers  against  expenses and  liabilities  in connection  with any proceeding
involving him by reason of his being or having been a director or officer if (a)
he acted in good faith and in a manner he  reasonably  believed to be in, or not
opposed to, the best  interests  of the  Registrant  and (b) with respect to any
criminal  proceeding,  he had no  reasonable  cause to believe  his  conduct was
unlawful.  However, in a proceeding by or in the right of the Registrant,  there
shall be no  indemnification  in respect of any  liabilities  or expenses if the
officer or director shall have been adjudged liable to the Registrant unless the
court  in such  proceeding  determines  he is  entitled  to  indemnity  for such
liabilities and/or expenses. Furthermore, no indemnification shall be made to or
on behalf of a director  or officer if a judgment  or other  final  adjudication
adverse to such director or officer  establishes  that his acts or omissions (a)
were in breach of his duty of loyalty to the  Registrant  and its  stockholders,
(b) were  not in good  faith  or  involved  a  knowing  violation  of law or (c)
resulted in receipt by the director or officer of an improper  personal benefit.
The NJBCA  defines an act or omission in breach of a person's duty of loyalty as
an act or  omission  which that  person  knows or believes to be contrary to the
best interests of the Registrant or its stockholders in connection with a matter
in which he has a material  conflict  of  interest.  If a director or officer is
successful in a proceeding,  the statute mandates that the Registrant  indemnify
him against expenses.

         The Registrant's Restated Certificate of Incorporation, as permitted by
New Jersey law,  eliminates the personal liability of the directors and officers
to the Registrant or its  stockholders for monetary damages for breaches of such
director's  or officer's  duty of care or other duties as a director or officer;
except  liabilities  for any breach of duty based upon an act or omission (a) in
breach of such person's duty of loyalty to the corporation or its  stockholders,
(b) not in good faith or involving a knowing  violation of law or (c)  resulting
in receipt by such person of an improper  personal  benefit.  In  addition,  the
Registrant's Restated By-laws provide broad indemnification  rights to directors
and  officers so long as the director or officer  acted in a manner  believed in
good faith to be in or not opposed to the best  interest of the  Registrant  and
with respect to criminal  proceedings if the director had no reasonable cause to
believe  his or her conduct  was  unlawful.  The  Registrant  believes  that the
protection  provided by these  provisions  will help the Registrant  attract and
retain  qualified  individuals  to  serve  as  officers  and  directors.   These
provisions  also will  limit the  remedies  available  to a  stockholder  who is
dissatisfied  with a Board  decision  protected  by these  provisions,  and such
stockholder's only remedy may be to bring a suit to prevent the Board's action.

         The Registrant  maintains a directors and officers liability  insurance
policy.

         As of October 28, 1998, the Registrant  entered into an Indemnification
Agreement with each Director of the  Registrant,  providing  that,  with certain
exceptions,  the  Registrant  would hold harmless and indemnify each Director in
connection with his  directorship  to the extent  permitted under the New Jersey
Business  Corporation  Act. More  specifically,




                                      II-1
<PAGE>

the  Indemnification  Agreement  provides  that the  Registrant  is obligated to
indemnify  each  Director  against all  reasonable  costs,  expenses  (including
attorneys' fees),  fines,  judgments,  and settlement amounts that such Director
may  incur  in  connection  with any  actual  or  threatened  action,  suit,  or
proceeding (whether, civil, criminal,  investigative or administrative) to which
such Director is, or may be, a party by reason of his position as Director or as
a  director,  officer,  employee,  or agent of any other  company  to which such
Director provides services at the request of the Registrant.

ITEM 16.  EXHIBITS

         (a)  Exhibits.  Attached hereto are the following exhibits:

              EXHIBIT
               NUMBER                   DESCRIPTION OF EXHIBIT
              -------      ----------------------------------------------------
                5.1        Opinion of Sullivan & Cromwell
               23.1        Consent of Sullivan & Cromwell  (included as part of
                           Exhibit  5.1)
               23.2        Consent  of  Arthur   Andersen  LLP, independent
                           public accountants
               23.3        Consent of KPMG LLP
               24          Power of Attorney

ITEM 17.  UNDERTAKINGS

         The Registrant hereby undertakes:

               (1) To file, during any period in which offers or sales are being
          made, a post-effective amendment to this registration statement:

                    (a) To include any prospectus  required by Section  10(a)(3)
               of the Securities Act of 1933 (as amended,  and together with the
               rules and regulations thereunder, the "Securities Act");

                    (b) To reflect in the prospectus any facts or events arising
               after the effective  date of the  registration  statement (or the
               most recent post-effective amendment thereof) which, individually
               or in  the  aggregate,  represent  a  fundamental  change  in the
               information   set   forth   in   the   registration    statement.
               Notwithstanding the foregoing, any increase or decrease in volume
               of securities  offered (if the total value of securities  offered
               would not exceed  that which was  registered)  and any  deviation
               from the low or high end of the estimated  maximum offering range
               may be  reflected  in the  form  of  prospectus  filed  with  the
               Commission  pursuant  to Rule  424(b) if, in the  aggregate,  the
               changes in volume and price  represent  no more than a 20 percent
               change  in  the   maximum   offering   price  set  forth  in  the
               "Calculation  of   Registration   Fee"  table  in  the  effective
               registration statement.

                    (c) To include any material  information with respect to the
               plan of distribution not previously disclosed in the registration
               statement  or any  material  change  to such  information  in the
               registration statement;

         provided,  however,  that paragraphs  (1)(a) and (1)(b) do not apply if
         the information  required to be included in a post-effective  amendment
         by those  paragraphs  is  contained in periodic  reports  filed with or
         furnished to the Commission by the registrant pursuant to Section 13 or
         Section 15(d) of the Securities  Exchange Act of 1934 (as amended,  and
         together with the rules and  regulations  thereunder,  the  "Securities
         Exchange Act") that are  incorporated by reference in the  registration
         statement.

               (2) That, for the purpose of determining  any liability under the
          Securities Act, each post-effective  amendment shall be deemed to be a
          new registration statement relating to the securities offered therein,
          and the offering of such securities at that time shall be deemed to be
          the initial bona fide offering thereof.



                                      II-2
<PAGE>

               (3) To  remove  from  registration  by means of a  post-effective
          amendment any of the securities  being  registered which remain unsold
          at the termination of the offering.

               (4) That,  for purposes of  determining  any liability  under the
          Securities Act, each filing of the Registrant's annual report pursuant
          to Section 13(a) or Section 15(d) of the Securities Exchange Act (and,
          where  applicable,  each filing of an employee  benefit  plan's annual
          report pursuant to Section 15(d) of the Securities  Exchange Act) that
          is  incorporated by reference in the  registration  statement shall be
          deemed to be a new registration  statement  relating to the securities
          offered  therein,  and the  offering of such  securities  at that time
          shall be deemed to be the initial bona fide offering thereof.

               (5) Insofar as indemnification  for liabilities arising under the
          Securities Act may be permitted to directors, officers and controlling
          persons of the  Registrant  pursuant to the foregoing  provisions,  or
          otherwise (other than pursuant to insurance),  the Registrant has been
          advised that in the opinion of the Commission such  indemnification is
          against  public  policy as  expressed in the  Securities  Act and may,
          therefore,   be   unenforceable.   In  the  event  that  a  claim  for
          indemnification  against such  liabilities  (other than the payment by
          the Registrant of expenses incurred or paid by a director,  officer or
          controlling  person of the Registrant in the successful defense of any
          action,  suit or  proceeding  and other than  insurance  payments)  is
          asserted by such director, officer or controlling person in connection
          with the securities being  registered,  the Registrant will, unless in
          the opinion of its counsel the matter has been settled by  controlling
          precedent,  submit to a court of appropriate jurisdiction the question
          whether  such  indemnification  by  it is  against  public  policy  as
          expressed  in the  Securities  Act and will be  governed  by the final
          adjudication of such issue.


                                      II-3
<PAGE>
                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
Registrant  certifies it has reasonable  grounds to believe that it meets all of
the  requirements  for filing on Form S-3 and has duly caused this  Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the Township of Harding,  State of New Jersey on the 19th day of
November, 1999.

                                    DENDRITE INTERNATIONAL, INC.

                                    By: /s/ John E. Bailye
                                       -------------------------------------
                                       John E. Bailye
                                       Chief Executive Officer and President

                                POWER OF ATTORNEY

         KNOW  ALL MEN BY THESE  PRESENTS,  that  each  person  whose  signature
appears  below  constitutes  and appoints  John E. Bailye,  George T. Robson and
Christopher J. French, and each of them as his true and lawful  attorney-in-fact
and agent,  with full power of substitution and  resubstitution,  for him and in
his  name,  place  and  stead,  in any and all  capacities,  to sign any and all
amendments (including post-effective  amendments) to the Registration Statement,
or a  Registration  Statement for the same offering that is to be effective upon
filing pursuant to Rule 462(b) under the Securities Act of 1933, as amended, and
file the same,  with all  exhibits  thereto and other  documents  in  connection
therewith,  with the  Securities  and Exchange  Commission,  granting  unto said
attorneys-in-fact  and agents,  full power and  authority to do and perform each
and every  act and  thing  requisite  and  necessary  to be done as fully to all
extents and purposes as they might or could do in person,  hereby  ratifying and
confirming all that said  attorneys-in-fact  and agents may lawfully do or cause
to be done by virtue hereof.

         Pursuant to the requirements of the Securities Act of 1933, as amended,
this  Registration  Statement has been signed below by the following  persons in
the capacities indicated on the 19th day of November, 1999.


               NAME                                      TITLE
- -------------------------------------   ----------------------------------------


/s/John E. Bailye
- ------------------------------------
          John E. Bailye                Chief Executive Officer,  President and
                                        Chairman (Principal Executive Officer)


/s/George T. Robson
- ------------------------------------
         George T. Robson               Senior   Vice   President   and   Chief
                                        Financial Officer (Principal  Financial
                                        and Accounting Officer)


/s/Bernard M. Goldsmith
- ------------------------------------
       Bernard M. Goldsmith             Director


/s/Edward J. Kfoury
- ------------------------------------
         Edward J. Kfoury               Director


/s/Paul A. Margolis
- ------------------------------------
         Paul A. Margolis               Director


/s/John H. Martinson
- ------------------------------------
         John H. Martinson              Director


/s/Terence H. Osborne
- ------------------------------------
        Terence H. Osborne              Director

                                      II-4
<PAGE>



<TABLE>
<CAPTION>
                                         EXHIBIT INDEX

Exhibit
Number                   Description of Exhibit                               Location
- --------  ---------------------------------------------------   -------------------------------
<S>       <C>                                                   <C>
 5.1      Opinion of Sullivan & Cromwell                        Filed herewith.
23.1      Consent of Sullivan & Cromwell                        Included in Exhibit 5.1.
23.2      Consent of Arthur Andersen LLP, independent public    Filed herewith.
          accountants
23.3      Consent of KPMG LLP                                   Filed herewith
24        Power of Attorney                                     Included in signature pages
                                                                of this Registration Statement.
</TABLE>





                                                                     Exhibit 5.1
<TABLE>
<S>                                               <C>
SULLIVAN & CROMWELL

NEW YORK TELEPHONE: (212) 558-4000
TELEX: 62694 (INTERNATIONAL) 127816 (DOMESTIC)                       125 Broad Street, New York 10004-2498
CABLE ADDRESS: LADYCOURT, NEW YORK                                     __________
FACSIMILE: (212) 558-3588 (125 Broad Street)
                                                  1701 PENNSYLVANIA AVE, N.W., WASHINGTON, D.C. 20006-5805
                                                            1888 CENTURY PARK EAST, LOS ANGELES 90067-1725
                                                                             8, PLACE VENDOME, 75001 PARIS
                                                    ST. OLAVE'S HOUSE, 9a IRONMONGER LANE, LONDON EC2V 8EY
                                                                        101 COLLINS STREET, MELBOURNE 3000
                                                            2-1, MARUNOUCHI 1-CHOME, CHIYODA-KU, TOKYO 100
                                                                     NINE QUEEN'S ROAD, CENTRAL, HONG KONG
                                                                 OBERLINDAU 54-56, 60323 FRANKFURT AM MAIN
</TABLE>

                                                            November 19, 1999



Dendrite International, Inc.,
   1200 Mount Kemble Avenue,
      Morristown, NJ 07960-6797.


Dear Sirs:

         In connection  with the  registration  under the Securities Act of 1933
(the "Act") of 2,351,354 shares (the "Securities") of common stock,  without par
value,  of  Dendrite   International,   Inc.,  a  New  Jersey  corporation  (the
"Company"),  we, as your special counsel,  have examined such corporate records,
certificates  and  other  documents,  and  such  questions  of  law,  as we have
considered  necessary or appropriate for the purposes of this opinion.  Upon the
basis  of  such  examination,  we  advise  you  that,  in our  opinion:

         (1) The  Securities  have been  validly  issued  and are fully paid and
nonassessable.

         The  foregoing  opinion  is  limited  to the  laws of the  State of New
Jersey,  and we are  expressing  no  opinion as to the effect of the laws of any
other jurisdiction.

         We have  relied as to certain  matters  on  information  obtained  from
public officials, officers of the Company and other sources believed by us to be
responsible.


<PAGE>



         We hereby  consent to the  filing of this  opinion as an exhibit to the
Registration Statement and to the reference to us under the heading "Validity of
Common Stock" in the Prospectus. In giving such consent, we do not thereby admit
that we are in the category of persons whose consent is required under Section 7
of the Act.

                                   Very truly yours,


                                   /s/ Sullivan & Cromwell

                                      -2-


                                                                    EXHIBIT 23.2

                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

         As   independent   public   accountants,   we  hereby  consent  to  the
incorporation by reference in this Form S-3 Registration Statement of our report
dated August 16, 1999 included in Item 5 of Dendrite International,  Inc.'s Form
10-Q filed August 16, 1999.

                                                /s/Arthur Andersen LLP
Philadelphia, Pa.,                              Arthur Andersen LLP
   November 17, 1999





                                                                    EXHIBIT 23.3


                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

         We consent  to the  incorporation  by  reference  of our  report  dated
February  16,  1999  in  this  Form  S-3  Registration   Statement  of  Dendrite
International,  Inc. with respect to the balance sheets of CorNet International,
Ltd. as of December  31, 1998 and 1997,  and the related  statements  of income,
stockholders'  equity,  and cash  flows for each of the years in the  three-year
period  ended  December  31,  1998,  which  report  appears in the June 30, 1999
quarterly  report  on Form  10-Q of  Dendrite  International,  Inc.,  and to the
reference to our firm under the heading "Experts" in this prospectus.


                                              /s/KPMG LLP
                                              KPMG LLP

Allentown, Pennsylvania
November 19, 1999




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