QUANTECH LTD /MN/
POS AM, 1997-01-21
COMPUTER STORAGE DEVICES
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    As filed with the Securities and Exchange Commission on January 21, 1997
    
                                                      Registration No. 333-6809


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
   
            POST-EFFECTIVE AMENDMENT NO. 1 TO FORM SB-2 REGISTRATION
                  STATEMENT ON FORM S-3 REGISTRATION STATEMENT
    
                        Under The Securities Act of 1933

                                  QUANTECH LTD.
           (Name of Small Business Issuer as specified in its Charter)

    Minnesota                            3573                     41-1709417
(State or other Jurisdiction of (Primary Standard Industrial  I.R.S. Employer
Incorporation or Organization)   Classification Code Number)  Identification
                                                              Number)

                                  Quantech Ltd.
                             1419 Energy Park Drive
                            St. Paul, Minnesota 55108
                                 (612) 647-6370

                   (Address and Telephone Number, of Principal
               Executive Offices and Principal Place of Business)


                              R.H. Joseph Shaw, CEO
                                  Quantech Ltd.
                             1419 Energy Park Drive
                            St. Paul, Minnesota 55108
                                 (612) 647-6370


                       (Name, Address and Telephone Number
                              of Agent for Service)

                                   Copies to:
   
                             Timothy M. Heaney, Esq.
                            Fredrikson & Byron, P.A.
                       900 Second Avenue South, Suite 1100
                          Minneapolis, Minnesota 55402
                                 (612) 347-7000
    
     Approximate  date of proposed  sale to the public:  From time to time after
the  effective  date of this  Registration  Statement  as  determined  by market
conditions and other factors.

     If any of the securities being registered on this form are to be offered on
a delayed or continuous basis,  pursuant to Rule 415 under the Securities Act of
1933, check the following box: [X]

     If this Form is filed to  register  additional  securities  of an  offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering: [ ]

     If this Form is a  post-effective  amendment  filed pursuant to Rule 462(c)
under the Securities Act, please check the following box and list the Securities
Act  registration   statement  number  of  the  earlier  effective  registration
statement for the same offering: [ ]

     If delivery of the  prospectus is expected to be made pursuant to Rule 434,
please check the following box: [ ]

<PAGE>

                         CALCULATION OF REGISTRATION FEE
===============================================================================
<TABLE>
<CAPTION>
                                                                              Proposed
 Title of each class                                 Proposed maximum          maximum
 of securities to be            Amount to be          offering price          aggregate          Amount of
      registered                registered            per share(1)       offering price(1)  registration fee

<S>                            <C>                      <C>                <C>                   <C>    
Common Stock ($.01 par value)   49,021,530 shares(2)     $0.8435            $41,349,661          $14,259
                                          
</TABLE>

(1)      For purposes of calculating  the  registration  fee in accordance  with
         Rule 457(c) under the Securities  Act of 1933, as amended,  such amount
         is based upon the average of the bid and asked  prices of  registrant's
         Common Stock on June 20, 1996.
(2)      Includes 11,940,103 shares that may be issued upon exercise of 
         outstanding Warrants.

The Registrant hereby amends this  Registration  Statement on such date or dates
as may be necessary to delay its effectiveness until the Registrant shall file a
further amendment which  specifically  states that this  Registration  Statement
shall  thereafter  become  effective  in  accordance  with  Section  8(a) of the
Securities Act of 1933, as amended,  or until the  Registration  Statement shall
become effective on such date as the Commission, acting pursuant to said Section
8(a), may determine.

<PAGE>


   
                     SUBJECT TO COMPLETION, JANUARY 21, 1997
    


PROSPECTUS




                                  QUANTECH LTD.

                        49,021,530 SHARES OF COMMON STOCK


     This Prospectus relates to the offer and sale of up to 49,021,530 shares of
Common  Stock (the  "Shares"),  par value $.01 per share,  of Quantech  Ltd.,  a
Minnesota  corporation  (the  "Company"  or  "Quantech"),  by  persons  who  are
currently  shareholders  of the  Company's  Common  Stock or who may become such
holders  upon  exercise of Warrants to purchase  shares of Company  Common Stock
(the "Selling  Shareholders").  The Selling  Shareholders may offer their Shares
from time to time  through or to  brokers  or  dealers  in the  over-the-counter
market  at  market  prices  prevailing  at the  time  of  sale or in one or more
negotiated  transactions at prices acceptable to the Selling  Shareholders.  The
Company  will not  receive  any  proceeds  from sale of  Shares  by the  Selling
Shareholders. See "Plan of Distribution."

     The Company will bear all expenses of the offering  (estimated at $35,000),
except  that the  Selling  Shareholders  will pay any  applicable  underwriter's
commissions and expenses,  brokerage fees or transfer taxes, as well as any fees
and disbursements of counsel and experts for the Selling Shareholders.

   
     Quantech's Common Stock is traded on the local  over-the-counter and Nasdaq
Bulletin  Board markets under the symbol of QQQQ.  The closing sale price of the
Common  Stock on January 20,  1997,  as  reflected on such markets was $0.55 per
share.
    

                            -------------------------

   
                 The Common Stock offered by this Prospectus is
               speculative and involves a high degree of risk. See
                      "Risk Factors" beginning on page 4."
    
                            -------------------------


          THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE
           SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES
            COMMISSION NOR HAS THE SECURITIES AND EXCHANGE COMMISSION
               OR ANY STATE SECURITIES COMMISSION PASSED UPON THE
               ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRE-
                SENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.




   
    The date of this Prospectus is              , 1997
    

<PAGE>




     No  person  is  authorized  to  give  any   information   or  to  make  any
representations, other then those contained or incorporated by reference in this
Prospectus,  in connection with the offering  contemplated hereby, and, if given
or made, such information or  representations  must not be relied upon as having
been authorized by the Company.  This Prospectus does not constitute an offer to
sell  or a  solicitation  of an  offer  to buy any  securities  other  than  the
registered  securities to which it relates or in any  jurisdiction to any person
to whom it is unlawful to make such offer or solicitation in such  jurisdiction.
Neither the delivery of this Prospectus nor any sale made hereunder shall, under
any  circumstances,  create any implication that there has been no change in the
affairs of the Company since the date hereof or that the  information  contained
or incorporated by reference  herein is correct as of any time subsequent to its
date.

   
                              AVAILABLE INFORMATION

     Prior to this  Offering,  the  Company  has been  subject to the  reporting
requirements of the Securities Exchange Act of 1934 (the "Exchange Act"), and in
accordance therewith files reports,  proxy statements and other information with
the Commission.  The Company has filed with the  Washington,  D.C. Office of the
Commission a Registration Statement under the Securities Act of 1933, as amended
(the "Securities Act"), with respect to the sale of the Shares.  This Prospectus
does not contain all of the information set forth in the Registration Statement,
certain  portions  of which  have been  omitted  as  permitted  by the rules and
regulations  of the  Commission.  For further  information  with  respect to the
Company  and  the  Shares,  reference  is made  to the  Registration  Statement,
including the exhibits  thereto.  Statements  contained in this Prospectus as to
the contents of any contract or other document  referred to are not  necessarily
complete, and in each instance reference is made to the copy of such contract or
other  document  filed  as  an  exhibit  to  the  Registration  Statement.   The
Registration  Statement and the Company's Exchange Act reports, proxy statements
and other information may be inspected by anyone without charge at the principal
office of the Commission at 450 Fifth Street, N.W.,  Washington,  D.C. 20549, or
at one of the  Commission's  regional  offices:  500 West  Madison,  Suite 1400,
Chicago, Illinois 60661-2511 and 7 World Trade Center, 13th Floor, New York, New
York,  10048.  Copies of all or any part of such  material may be obtained  upon
payment  of the  prescribed  fees  from  the  Public  Reference  Section  of the
Commission at 450 Fifth Street, N.W.,  Washington,  D.C. 20549. The Registration
Statement and the Company  Exchange Act filings may also be accessed through the
Commission's Web site (http://www.sec.gov).

                       DOCUMENTS INCORPORATED BY REFERENCE

     The following documents filed by the Company with the Commission are hereby
incorporated by reference in this Prospectus:

     1.   The Company's Annual Report on Form 10-KSB for the fiscal year ended
          June 30, 1996.
     2.   The Company's Quarterly Report on Form 10-QSB for the quarter ended
          September 30, 1996.

     All documents filed by the Company pursuant to Sections 13(a), 13(c), 14 or
15(d) of the  Exchange  Act after the date of this  Prospectus  and prior to the
termination of the offering of the Shares shall be deemed to be  incorporated by
reference in this  Prospectus and to be a part hereof from the date of filing of
such documents.

     The Company  will provide  without  charge to each  person,  including  any
beneficial  owner,  to whom a copy of this  Prospectus  is  delivered,  upon the
written or oral  request of such person,  a copy of any or all of the  documents
incorporated  herein by reference (not including the exhibits to such documents,
unless  such  exhibits  are  specifically  incorporated  by  reference  in  such
documents).  Requests for such copies  should be directed to Gregory G. Freitag,
Chief  Financial  Officer,  Quantech  Ltd.,  1419 Energy Park Drive,  St.  Paul,
Minnesota 55108, telephone (612) 647-6370.

    

<PAGE>

        

                                 COMPANY SUMMARY
   

     Quantech Ltd. ("Quantech" or the "Company") is a Minnesota company with its
principal  executive  offices  located at 1419  Energy  Park  Drive,  St.  Paul,
Minnesota  55108,  telephone (612)  647-6370.  Quantech is  commercializing  its
proprietary Surface Plasmon Resonance ("SPR") technology for use in the critical
care medical diagnostic  market.  SPR, the core technology of Quantech's medical
diagnostic  system,  enables the Company to integrate  the  existing  diagnostic
methodologies  of  immunoassays,  DNA probes and chemical binding into a single,
simple,  economical system in order to provide rapid,  quantitative,  diagnostic
results near the patient's bedside. The Quantech system  configuration  consists
of a small,  bench top instrument  and a series of  disposables  each offering a
particular test or series of tests.  This system has the ability to analyze body
fluids (e.g.,  whole blood,  urine,  saliva) without  preparation or addition of
reagents by lab technicians,  providing hospital  physicians faster test results
than currently obtained from labs.

     Excluding  home  diagnostics,  the overall world wide  in-vitro  diagnostic
market is growing,  estimated at $13.2 billion in 1994,  and expected to grow to
$17.5 billion by the year 2000.  Central labs currently account for the majority
of this market  while Point of Care  ("POC")  products  represents  only a small
portion. Introduction of additional POC products, such as Quantech's system, are
expected  to cause the POC  market to gain a larger  percentage  of the  overall
in-vitro  diagnostic market. The extent of such market shift will be affected by
the ability of POC  products  to provide  fast,  cost  effective  and  efficient
products.  The Company's  market entry  strategy  focuses its efforts on the POC
segment,  specifically the Critical Care Units of hospitals. The POC segment has
become important for health care  administrators  and third party payers seeking
to bring more rapid decision making to the patient's bedside, thereby decreasing
the overall cost of care.

     Quantech's   business   strategy  is  to  capitalize  on  the  flexibility,
sensitivity  and relatively  low cost of its diagnostic  system to penetrate the
diagnostic market.  Quantech's  intended entry into this market will be Critical
Care Units of hospitals,  the first unit being the Emergency  Department  ("ED")
where the most pressing and unmet  customer  needs are found.  The Critical Care
Units  represent  a  significant  market  as they  require  a  number  of  rapid
turn-around tests.  Although there are some POC tests available for the Critical
Care Units, the Company is not aware of any existing POC product that provides a
single  instrument  that  will  perform  most of the tests  required  in the ED.
Additionally,  minimal  competition  exists  for  POC  products  in the ED  from
multinational companies that are focused on the central lab market.

     There are  approximately  30 commonly ordered tests in the ED, all of which
are ordered STAT (very urgent).  Some of the most important  diagnostic tests in
the ED are  cardiac  markers.  These  tests help to  identify  whether a patient
experiencing chest pain has suffered a myocardial infarction (heart attack). The
Company  believes  there  is  currently  no  technology  available  that has the
capability  of   economically   performing   STAT,   whole  blood  testing  with
quantitative  results.  Quantech's  first tests are  expected to quantify  these
markers in approximately five minutes through its objective, computer-controlled
system. Similar results are presently available from the central lab in 45 to 90
minutes.  Quantech's  price  to the  customer  will be less  than  existing  POC
products while offering the advantages of rapid quantification.

     Quantech  believes  the  benefits of its system over other POC products are
that the same  instrument  will be able to be used for a full range of tests and
provide  quantitative  results.  After  the  initial  introduction  of tests for
myocardial infarction,  the Company intends to introduce additional tests at the
rate of one per  quarter.  Selection  of these  tests will be based upon  market
demand, ease of development,  regulatory hurdles and profit margins. The Company
intends future expansion into other critical care diagnostic  markets which have
needs similar to the ED. Quantech  believes the  capabilities of its system as a
broad, flexible diagnostic testing platform meets the needs of the critical care
diagnostic  market and will  enable  Quantech  to be  competitive  in the global
medical diagnostics market.

    



<PAGE>

        
                                  RISK FACTORS

     An investment in the securities  offered hereby is speculative and involves
a high degree of risk In addition to the other  information in this  Prospectus,
the following factors should be considered  carefully by potential purchasers in
evaluating an investment in the Common Stock of the Company.

No History of Operations; Development Stage Company; Going Concern Uncertainty
   
     The Company (through  predecessor  entities) was organized in December 1989
and acquired its technology in November  1991.  Since November 1991, the Company
has been conducting development of SPR technology and the associated patents and
proprietary  information  encompassed in the License, as defined below. To date,
the  Company  does not have a product  ready to be  brought  to  market  and has
experienced  delays in completing  development,  but is continuing  research and
development on its prototype and associated test disposables.  Accordingly,  the
Company has no operating history and its proposed  operations are subject to all
of  the  risks  inherent  in a new  business  enterprise,  including  commercial
development of its products, lack of marketing experience and lack of production
history.

     The likelihood of the success of the Company must be considered in light of
the expenses,  difficulties and delays frequently encountered in connection with
the start-up of new  businesses  and the  competitive  environment  in which the
Company will operate.  The Company has not had significant  revenues to date. As
of September 30, 1996,  the Company had an accumulated  deficit of  $11,189,637.
The report of the independent auditors on the Company's financial statements for
the period ended June 30, 1996,  includes an explanatory  paragraph  relating to
the  uncertainty of the Company's  ability to continue as a going  concern.  The
Company  is  a  development   stage  company  which  has  suffered  losses  from
operations,  requires additional financing, and ultimately needs to successfully
attain  profitable  operations.  These factors raise substantial doubt about the
Company's ability to continue as a going concern. There can be no assurance that
the Company will be able to develop a  commercially  viable product or marketing
system or attain profitable operations.
    
Future Capital Needs
   
     The  Company  does  not  have  sufficient  funds  to  commence   commercial
production and sales of its system.  The Company's  ability to begin  commercial
production  and sales of its system will depend upon the continued  availability
of  investment  capital,  funding  made by  strategic  partner(s)  or  licensing
revenues,  until  revenues  from sale of the  instruments  and  associated  test
disposables are sufficient to maintain operations.  Additional funds may have to
be raised through equity or debt  financing.  The Company has no commitments for
any  additional  equity or debt financing and there can be no assurance that any
such  commitments can be obtained on favorable terms, if at all. Such additional
financing  may result in  dilution  to Company  shareholders.  If funding is not
available when needed, the Company may be forced to cease operations and abandon
its  business.  In such  event,  Company  shareholders  could lose their  entire
investment.
    
New Product Development
   
     The Company's reading  instrumentation and associated disposables are under
development.  Such  development  is being  conducted  by the Company  using both
internal resources and outside contractors.  To date, the Company and certain of
its outside contractors have had difficulty meeting their development timetables
and budget. No assurance can be given that the Company's  development  timetable
can be  met,  that  the  budget  for  development  will be  maintained,  or that
development efforts will be successful.
    
Uncertainty of Market Acceptance
   
     The  commercial  success of the  Company's  products will depend upon their
acceptance  by the  medical  community  and  third-party  payors as  useful  and
cost-effective.  Market  acceptance will depend upon several factors,  including
    
<PAGE>

   
the establishment of the utility and  cost-effectiveness of the Company's tests,
the receipt of regulatory  clearances in the United States and elsewhere and the
availability of third-party reimbursement.  The availability of POC test systems
for a wide  variety  of tests has been  limited  to date.  The  Company  is thus
targeting an emerging market. Diagnostic tests similar to those developed by the
Company are generally performed by a central laboratory at a hospital or clinic.
The approval of the purchase of diagnostic  equipment by a hospital is generally
controlled  by its  central  laboratory.  The  Company  expects  there  will  be
resistance  by  central  laboratories  to  yield  control  of  tests  they  have
previously  performed.  The Company will also have to  demonstrate to physicians
that its  diagnostic  products  perform as  intended,  meaning that the level of
accuracy and precision  attained by the Company's products must be comparable to
test  results  achieved  by  the  central  laboratory  systems.  Failure  of the
Company's  products to achieve market  acceptance or third-party  payor approval
would have a material adverse effect on the Company.
    

Lack of Marketing Experience

     The Company has had no  experience  in  marketing  its system.  The Company
believes  that the ED market is focused  enough that a small sales and marketing
force can produce significant  results,  however,  there is no guaranty that the
Company's sales and marketing plans will succeed.

Lack of FDA Product Approval
   
     The Company's products will be regulated as medical devices by the Food and
Drug Administration ("FDA") under the Federal Food, Drug, and Cosmetic Act ("FDC
Act"),   and   as   such   require   premarket   regulatory   clearance   before
commericialization  in the United  States.  The Company  believes that premarket
clearance  can be obtained for its  systems,  except for a few tests the Company
may  introduce  at a  later  time,  through  submission  of a  510(K)  premarket
notification  ("510(K)  Notification")  demonstrating the product's  substantial
equivalence to another device legally marketed  pursuant to 510(K)  Notification
clearance. The Company will have to perform in-house clinical trials designed to
produce the data necessary to  demonstrate  the  substantial  equivalence of its
instrument and tests.  Although 510(K)  submissions are supposed to be completed
by the FDA within 90 days of submission,  there can be no assurance the FDA will
approve the Company's initial system pursuant to a 510(K) Notification, or do so
in a timely manner,  and therefore there can be no assurance of when the Company
will be able to  introduce  its  initial  system in the  United  States.  If the
Company cannot  establish to the  satisfaction  of the FDA that its products are
substantially  equivalent,  the  Company  will have to seek  premarket  approval
("PMA") of its system,  requiring  submission of a PMA application  supported by
extensive data to prove safety and efficacy. If a PMA is required,  introduction
of the initial system would likely be significantly  delayed, which could have a
material  adverse  effect  on the  Company.  By  regulation,  FDA  review of PMA
applications is required within 180 days of its acceptance for filing;  however,
reviews more often occur over a significantly  protracted period,  usually 12 to
18 months, and a number of products have never been cleared.
    
Limited Manufacturing and Production Experience

     To be successful  the Company must  manufacture  its products in compliance
with regulatory  requirements,  in sufficient  quantities and on a timely basis,
while  maintaining  product  quality and  acceptable  manufacturing  costs.  The
Company  will have to establish a  manufacturing  facility,  or contract  with a
third party for manufacturing,  which is registered with the FDA.  Production of
the Company's  disposables requires the placement of antibodies or other binding
reagents on metalized grating surfaces. The chemical and physical conditions for
coating are substantially  equivalent to those used to produce other solid state
binding assays.  Although the Company believes that its production  methods will
be effective for manufacturing  its disposables,  there can be no assurance that
the methods  will be  applicable  to all the tests it expects to develop or that
the Company will be able to manufacture  accurate and reliable products in large
commercial  quantities on a timely basis and at an acceptable cost. Inability to
manufacture a full range of diagnostic tests would limit the Company's access to
its intended market.

<PAGE>

Competition
   
     The diagnostic testing market is highly competitive. As POC markets expand,
the Company expects that  manufacturers  of central and STAT laboratory  testing
equipment  will compete to maintain  their revenue and market share and that new
POC products  will be  developed.  All of the  industry  leaders and many of the
other  companies   participating  in  this  market  have  substantially  greater
resources  than the  resources  available  to the  Company,  including,  but not
limited to, financial resources and skilled personnel.
    
Technological Obsolescence

     The Company  operates in a market  characterized  by rapid and  significant
technological  change. While the Company is not aware of any developments in the
medical  industry which would render the Company's  current or planned  products
less   competitive   or  obsolete,   there  can  be  no  assurance  that  future
technological  changes or the  development  of new or  competitive  products  by
others will not do so. To remain competitive,  the Company must continually make
substantial expenditures for development of both equipment and disposables.

Obtaining Antibodies and Chemistries

     Many of the chemistries that will be necessary for the Company's diagnostic
system must be obtained  through  commercial  suppliers  or  agreements  for the
licensing of such  chemistries.  Although the Company believes it can obtain the
necessary  chemistries,  there can be no assurance that the Company will be able
to make  satisfactory  arrangements  to  provide  its  customers  with as wide a
variety of products as they might  desire.  The lack of a  sufficient  number of
chemistries  would greatly limit the Company's  ability to market its diagnostic
system.
        

Patent Protection
   
     No  assurance  can  be  given  that  other   companies   will  not  develop
technologies  substantially  equivalent  to  those  owned or to be  acquired  or
developed  by the  Company  or that  the  Company  will be able to  protect  its
proprietary  technology.  The  Company is not aware of any issued  patents  that
would  prohibit  the use of any  technology  the  Company  currently  has  under
development.  However,  patents  may  exist  or  issue  in the  future  to other
companies covering elements of the Company's systems.  The existence or issuance
of such  patents  may require  the  Company to make  significant  changes in the
design of its systems or operational  plans.  Although the Company believes that
its proposed products will not infringe patent rights of others, there can be no
assurance  that such  infringement  does not, or will not, exist with respect to
the  completed  product.  The Company has not  conducted an  independent  patent
search or  evaluation  with  respect  to the SPR  technology.  Ares-Serono,  the
licensor to the Company of its basic SPR  technology,  has made no warranties as
to the  enforceability of any of its patents or the commercial  potential of the
technology.  Although  Ares-Serono has the obligation to defend the patents they
have licensed to the Company,  Quantech will be  responsible  for the defense of
any patents issued to it. Cost of defending patents can be substantial.
    
Government Regulation
   
     If the  Company  becomes a provider of health  care  diagnostic  devices as
intended,  the Company will be subject to laws and  regulations  administered by
federal,  State and foreign  governments.  The degree of regulation and areas of
concern differ in each country or region. The Company will be required to comply
with  regulations  regarding  product approval and performance and, in addition,
regulations  concerning  electronic  devices.  The industry in which the Company
expects to operate is subject to frequent regulatory changes and there can be no
assurance that the Company will be able to comply with  applicable  regulations.
In the event of noncompliance, the Company may be unable to market any products.
    

<PAGE>


Possibility of Exposure to Product Liability Claims

     The Company could be exposed to risk of product  liability  claims or other
lawsuits in the event of incorrect  diagnosis  utilizing  the SPR  equipment and
disposables  developed  by the  Company.  Although  the  Company  will  evaluate
obtaining liability insurance when the products come to market,  there can be no
assurance  that the Company will be able to obtain or maintain such insurance or
that the  Company  will not be  subject  to claims  in  excess of its  insurance
coverage.

Absence of Dividends

     The Company has not declared or paid any cash dividends on its Common Stock
since its inception and the Board of Directors  presently  intends to retain all
earnings  for  use by  the  Company  for  the  foreseeable  future.  Any  future
determination  as to  declaration  and payment of dividends  will be made at the
discretion  of the Board of Directors  and will depend upon a number of factors,
including,  among others,  earnings of the Company,  the operating and financial
condition  of the  Company,  the  Company's  capital  requirements,  and general
business conditions.

Shares Eligible for Future Sale
   
     Including  the Shares  available  pursuant to this  Prospectus,  all of the
Company's  outstanding  stock may be sold in the  public  market.  In  addition,
11,940,103 of a total of 15,948,603 shares that may be obtained upon exercise of
outstanding  options and warrants are also included for resale  pursuant to this
Prospectus.
    
Limited Market for Securities
   
     There is a limited trading market for the Company's Common Stock,  which is
not listed on any stock  exchange or Nasdaq.  Although  trading in the Company's
Common Stock does occur on a consistent  basis,  the volume of shares traded has
been sporadic. There can be no assurance that an established trading market will
develop,  the  current  market  will be  maintained  or a liquid  market for the
Company's Common Stock will be available in the future.
    

<PAGE>

        

                       PRINCIPAL AND SELLING SHAREHOLDERS

     Set forth  below are the names of:  (a)  persons  who are known to own more
than 5% of the Company's Common Stock;  (b) each executive  officer named in the
Summary  Compensation table; (c) each director of the Company; (d) all directors
and executive officers as a group; and (e) Selling  Shareholders.  The following
table  sets forth as of the date of the  Prospectus  beneficially  owned  shares
which include any shares that may be acquired within 60 days of the date of this
Prospectus  upon exercise of options or warrants,  the number of Shares  offered
hereby and the percentage of the outstanding  Common Stock to be owned if all of
the Shares registered hereunder are sold by the Selling Shareholders.

<TABLE>
<CAPTION>

                                                                        % Of
                                         Number of Shares     No.      Shares
                                        Beneficially Owned  Shares     Owned
                                                   Warrant  Offered     After
    Name                                Shares     Shares   Hereby     Offering

<S>                                    <C>        <C>      <C>          <C>   
Ted & Mary Adams                        25,000              25,000        *
Theodore P. Adams                       40,000     10,000   50,000        *
American Heritage Fund                            250,000  250,000        *
Gerald L. Anderson                      25,000              25,000        *
Roy Anderson Jr.                       200,000     50,000  250,000        *
Roy Anderson III                       200,000     50,000  250,000        *
Gregory & Ann Anklam                    40,000     10,000   50,000        *
Menesa Anstalt                          50,000              50,000        *
Meleah T. & David M. Arnold            400,000    100,000  500,000        *
J. Marc Ashton                          40,000     10,000   50,000        *
Atwell & Co.                           928,000             928,000        *
Larry Auriana                          598,000             598,000        *
Bernard C. Baier                        50,000              50,000        *
John G. Ballenger                      200,000     50,000  250,000        *
Bank Heusser & Co. LTD                 400,000    100,000  500,000        *
W. William & Colette M. Bednarczyk     125,000             125,000        *
Richard T. Bennett                      50,000              50,000        *
Denis Berger                                      250,000  250,000        *
Les  Biller                            454,704             454,704        *
Nicolas C. Bluhm                       360,000    115,000  475,000        *
Jeffrey A. & Brenda L. Bowen            50,000              50,000        *
Donald A. Brattain                     450,000     50,000  500,000        *
Courtney W. Brown                      210,664     10,000  220,664        *
Paul R. Braun                           33,335              33,335        *
Richard M. Brown                        25,000              25,000        *
Ralph D. Burgess Jr.                    50,000              50,000        *
Timothy H. Burton                       50,000              50,000        *
Anthony Carideo                         40,000     10,000   50,000        *
Fred & Wendy Caslavka                   10,000              10,000        *
Joseph B. Catarious                    200,000     50,000  250,000        *
James A. Chapman                        30,000              30,000        *
Walter L. Chapman                       54,264              54,264        *
Lee S. Chapman                         538,000     25,000  235,000      0.7%
Martin Chelstrom                        10,000              10,000        *
Christianson Investment Co. LP         500,000    100,000  600,000        *

</TABLE>

<PAGE>

<TABLE>
<CAPTION>

   
                                                                        % Of
                                         Number of Shares      No.      Shares
                                        Beneficially Owned   Shares     Owned
                                                   Warrant   Offered    After
    Name                                Shares     Shares    Hereby    Offering

<S>                                 <C>          <C>       <C>            <C>   
Ann M. Christianson                     19,750      4,937     24,687        *
Lynn A. Christianson                    19,750      4,937     24,687        *
Warren G. Christianson                 800,036    120,378    920,414        *
Warren T. A. Christianson               19,750      4,937     24,687        *
Dual B. & Adelle Cooper                 10,000                10,000        *
Dave Cowley Pension Trust               50,000                50,000        *
Thomas A. Cullinan                      25,000                25,000        *
Francisco E. dela Rosa Jr.              17,000                17,000        *
Robert W. & Rita M. deWerd              48,000     12,000     60,000        *
Glenn Diamond                        1,115,037    600,000  1,715,037        *
Robert Diamond                         227,200               227,200        *
Michael H. Diemer                       50,000                50,000        *
John P. & Emily W. Dirksen              80,000     20,000    100,000        *
Arthur T. Donaldson                     25,000                25,000        *
DRAFTCO                                200,000     50,000    250,000        *
Neil Durhman                                      200,000    200,000        *
Paul Ehlen                              36,670      5,000     41,670        *
Stanley G. & Carol R. Eilers           958,000    190,000    790,000        *
Engelkes-Abels Funeral Home Inc.        80,000     20,000    100,000        *
W. Bruce Erickson                      167,464               167,464        *
Equity Securities Trading Co., Inc.       -         2,000      2,000        *
James E. Ernst                          17,500                17,500        *
Weems Estelle(1)                       560,000    450,000  1,010,000        *
Robert J. Evans                         40,000     10,000     50,000        *
Harvey Feldman                          25,000                25,000        *
Lee Felicetta                           40,000     10,000     50,000        *
Mary Jane Fleming                       84,268                84,268        *
John E. Feltl                             -         4,000      4,000        *
Founding Partners Limited 
  Partnership II                       200,000               200,000        *
Carol M. Freeman                        19,750      4,937     24,687        *
Gregory G. Freitag                     505,500(2) 100,000    100,000      1.1%
Robert D. Furst Jr.                    289,800               289,800        *
James M. Gahlon                         80,000                80,000        *
James Gahlon                            92,008                92,008        *
Robert W. Jr. & Patricia T. Gaines     100,000               100,000        *
Robert D. Gearou                        50,000                50,000        *
Robert L. Gearou                       250,000     62,500    312,500        *
Thomas W. Gearou                       250,000     50,000    300,000        *
Marvin A. Ginsburg                      40,000     10,000     50,000        *
Michael J. Glass                        16,670                16,670        *
Ronald L. Glassman                      50,000                50,000        *
Glymar Inc.                             40,000     10,000     50,000        *
David S. Goldsteen                   3,025,056             3,025,056        *
Mark Goldsteen                         400,000    100,000    500,000        *
Franklin N. Groves IRA                  25,000                25,000        *
Gummow Investments                      50,000                50,000        *
Troy Gummow                             50,000                50,000        *
    
</TABLE>

<PAGE>

<TABLE>
<CAPTION>

                                                                        % Of
                                         Number of Shares      No.      Shares
                                        Beneficially Owned   Shares     Owned
                                                   Warrant   Offered    After
    Name                                Shares     Shares    Hereby    Offering

<S>                                <C>           <C>       <C>           <C>   
Warren Guy & Lonnie K. Gummow           50,000                50,000        *
H. Eugene Hall                          52,232                40,000        *
James W. Hansen                         50,000                50,000        *
Thomas Harkness                        100,000     50,000    150,000        *
Craig Hartsburg                         25,000                25,000        *
Bill R. Hay                             80,000     15,000     95,000        *
Timothy Heaney                          20,000      5,000     25,000        *
Timothy Heaney IRA                       8,335                 8,335        *
Heartland Limited Partnership I        750,000               750,000        *
Thomas Craig Hense                      50,000                50,000        *
Julie A. Higgins                        19,750      4,937     24,687        *
George Holbrook                        454,672               454,672        *
Bruce Hubbard                           32,000      8,000     40,000        *
Richard G. & Diane L. Hubers            20,000                20,000        *
H. K. Financial Corp                 1,420,664    100,000    924,000      1.3%
Hynan Real Estate Partnership           25,000                25,000        *
Industricorp & Co. Inc.                127,600     44,400    172,000        *
Intermed Anstalt                       275,000     50,000    325,000        *
Charles A. Jacob                        20,000                20,000        *
Stanley J. Johnson                     250,000     75,000    325,000        *
Theodore Johnson                       100,000     25,000    125,000        *
Wesley E. Johnson Jr.                   65,000     10,000     75,000        *
James C. Jordan                         25,000                25,000        *
E. Elmer &E. Joyce Jutila               40,000     10,000     50,000        *
Jon E. Jutila                           40,000     10,000     50,000        *
Nasser J. Kazeminy                      85,000                85,000        *
Bernard M. S. Kegan                     40,000     10,000     50,000        *
Michael S. Kelly                          -         4,000      4,000        *
Kessler Ashler Group Limited 
  Partnership                          800,000    200,000  1,000,000        *
Kurt King DDS, IRA                     100,000     25,000    125,000        *
Steven G. King                         100,000     25,000    125,000        *
John G. Kinnard & Company Inc.(3)         -     3,078,500  3,078,500        *
Brandon Koress                         116,670     25,000    141,670        *
Mitchell Krieger                       175,000     37,500    212,500        *
David J. & Kathryn J. Kruskopf          40,000     10,000     50,000        *
Martin Lackner                         116,670     25,000    141,670        *
Lakewood Ortho Clinic-Mark Mills        40,000     10,000     50,000        *
Dennis J. LaValle                    1,000,360    175,000    886,345       .6%
Bruce A. Lawin                          40,000     10,000     50,000        *
Thomas F. Leahy                        100,000               100,000        *
Frank Lee                               92,800                92,800        *
Cheri E. Lefebvre                       10,000                10,000        *
Donald S. & Mary A.Leonard              84,264                84,264        *
Peter Lerner                           460,000               460,000        *
Lopresti Gabbay & Associates Inc.      400,000               400,000        *
C. S. Lozinski                          60,000     15,000     75,000        *
Roger Lucas                            100,000     25,000    125,000        *

</TABLE>

<PAGE>

<TABLE>
<CAPTION>
   
                                                                        % Of
                                         Number of Shares      No.      Shares
                                        Beneficially Owned   Shares     Owned
                                                   Warrant   Offered    After
    Name                                Shares     Shares    Hereby    Offering

<S>                                  <C>         <C>        <C>         <C>  
Wayne K. Lund                          792,000     150,000    590,000      *
James F. Lyons                         750,000(2)   50,000    300,000    1.1%
James F. Lyons & Eleanor Lyons          50,000                 50,000      *
Plato Mavroulis                        100,000      25,000    125,000      *
Lyle H. Maschoff                        25,000                 25,000      *
Kenneth Maus                            50,000                 50,000      *
Victor Mavar                           100,000      25,000    125,000      *
Adolfo M. Maglaya                       22,120                 16,000      *
Trustees of Adolfo Maglaya Profit 
  Sharing Trust                         33,762                 24,000      *
David Metz                              50,000      12,500     62,500      *
Robert T. Montague                     100,808                100,808      *
Joseph Mooibroek                        60,000      15,000     75,000      *
Sheliah Mulvaney                        16,665                 16,665      *
James S. Murphy                         80,000      20,000    100,000      *
Michael Nagel(4)                        22,898                 22,898      *
Andrea McCallister O'Connell           127,664      12,500    140,164      *
Robert R. McKiel                       881,330(5)             830,841      *
H. Vincent O'Connell                   345,864      32,500    378,364      *
Steve O'Hara                            40,000      10,000     50,000      *
Okabena Partnership K                2,765,328              2,765,328      *
Jay Osman                                5,000                  5,000      *
John & Delores Owensby                 340,000      90,000    430,000      *
Deming L. Payne                        260,000      90,000    350,000      *
Richard W. Perkins                     800,000(2)   50,000    350,000    1.1%
Jeff  Peterson                          41,864                 41,864      *
Patrick Peyton                          16,744                 16,744      *
Thomas J. Pierce                        40,000      10,000     50,000      *
William W. Prain                       100,000      25,000    125,000      *
Charlie H. Pulley                      342,000      75,000    417,000      *
Arthur Querfeld                         40,000                 40,000      *
Mary J. Rasley                          19,750       4,937     24,687      *
Willard Charles Rehbein                400,000     150,000    550,000      *
Victor P. Reim                          50,000                 50,000      *
Ben Reuben                              25,000                 25,000      *
River Edge Partners, Inc.              300,000     100,000    400,000      *
Kenneth S. Roberts                      50,000                 50,000      *
Richard Rog                             25,000                 25,000      *
Douglas Schmid                          25,000                 25,000      *
Robert A. & Lois R. Schmiege           100,000      37,500    137,500      *
Schneider Securities Inc.                           17,500     17,500      *
Thomas J. Schrade                      100,000                100,000      *
James R. Schroeder                      25,000                 25,000      *
John P. & Gloria E. Schweich            50,000      12,500     62,500      *
Sekhavat Ltd. Partnership              560,000     190,000    750,000      *
Byron G. Shaffer                       335,000                335,000      *
R.H. Joseph Shaw                     1,335,855(6)           1,246,262      *
Gerald J. Shink                         50,000                 50,000      *
    
</TABLE>


<PAGE>

<TABLE>
<CAPTION>
   
                                                                        % Of
                                         Number of Shares      No.      Shares
                                        Beneficially Owned   Shares     Owned
                                                   Warrant   Offered    After
    Name                                Shares     Shares    Hereby    Offering

<S>                                   <C>         <C>       <C>            <C>    
Patrick M.  Sidders                      72,136      6,000      78,136       *
Ronald & Catherine M. Silver             50,000                 50,000       *
Terryl Sinko                             50,000                 50,000       *
Soldier Creek Family Limited 
  Partnership                         2,200,000              2,200,000       *
Jeannette A. & John E. Slaughter         25,000                 25,000       *
Allan P.  Steffes                       100,000     25,000     125,000       *
Thomas E. Steinhaus                      50,000                 50,000       *
Michael Stone                              -         1,000       1,000       *
Ross Strehlow                            20,000                 20,000       *
Edward E. Strickland                    700,000(7)  50,000     250,000      1.1%
Strickland Family Limited Partnership   100,000                100,000       *
Douglas V. & Kathleen L. Swanson         25,000                 25,000       *
William R. & Catherine A. Swanson        40,000     10,000      50,000       *
Curtis R. Swenson                        25,000                 25,000       *
James W. Swenson                        200,400     50,100     250,500       *
James E. Tarr                            25,000                 25,000       *
David M. & Susan M. Thymian             508,000     50,500     202,500       *
Elizabeth J. Tonne                       50,000                 50,000       *
John M. Tonne                            50,000                 50,000       *
Larry & Gayla Torguson                   40,000     10,000      50,000       *
Marlin F. Torguson                    1,000,000    275,000   1,275,000       *
Ben Trainer                             255,000     75,000     330,000       *
Charles E. Underbrink                   325,000    125,000     450,000       *
Greg & Patricia Vogelpohl                35,000                 35,000       *
Randall S.& Nancy Brostrom Vollertdon    17,500                 17,500       *
Chris Warren                                       100,000     100,000       *
Larry Weaver(8)                           5,861    250,000     250,000       *
George Vitalis(9)                        61,000    250,000     250,000       *
Paul Walker                              25,000                 25,000       *
Willard Weikle                           45,000                 45,000       *
Kevin E. & Delana S. Were                17,000                 17,000       *
Donald Westrup                          272,328                250,000       *
Dr. Henry & Dr. Carolyn Wiggins         248,302                220,000       *
Frank W. Worms                           85,000                 85,000       *
Jeff M Zalasky                          310,024                310,024       *
Alvin Zelickson                          50,000     12,500      62,500       *
Richard J. Zentgraf                      50,000                 50,000       *
All directors and executive officers
 as a Group (6 persons)               5,022,685(10)250,000   3,127,103      3.7%
    
</TABLE>

*     Less than 0.5%.
   
(1)   Mr. Estelle was the Company's former Chairman of the Board.
(2)   Includes  500,000  shares  issuable upon exercise of options.  
      Mr.  Freitag is the Company's CFO and Executive V.P. of Corporate
      Development and Messrs. Lyon and Perkins are Company Directors.
(3)   John G. Kinnard and Company, Incorporated is the Company's Investment
      Banker.
    
      (Footnotes continued on next page)


<PAGE>


      (Footnotes  continued  from previous  page)
   
(4)   Mr. Nagel is the Company's Director of Sales and Marketing.
(5)   Includes  830,841 shares issuable upon exercise of warrants.  Mr. McKiel 
      is the Company's  Executive V.P. of Research and Development.
(6)   Includes  1,246,262  shares  issuable upon exercise of warrants and 37,925
      shares  held by Mr.  Shaw's  wife.  Also  includes  11,168  shares held by
      Spectrum Diagnostics, Inc.("SDI"), of which company Mr. Shaw is an officer
      and director,  but not a shareholder,  and by such position has voting and
      dispositive power over such shares.  Mr. Shaw is a director and CEO of the
      Company.
(7)   Includes  500,000 shares issuable upon exercise of options,  but excludes
      100,000 shares held by the Strickland Family Limited Partnership.  Mr. 
      Strickland is a director of the Company.
(8)   Dr. Weaver was a former director of the Company.
(9)   Mr. Vitalis was a former director and CEO of the Company.
(10)  Includes  4,077,103  shares issuable upon exercise of options and warrants
      and 11,168 shares held SDI. Excludes 100,000 shares held by the Strickland
      Family  Limited  Partnership.  The address of each  executive  officer and
      director of the Company is 1419 Energy Park Drive,  St.  Paul,  Minnesota,
      55108.
    
                            DESCRIPTION OF SECURITIES

     The following  description  of the Company's  capital stock is qualified in
its  entirety  by  reference  to the  Company's  Articles of  Incorporation,  as
amended, its Bylaws, and the Minnesota Business Corporation Act (the "MBCA").

General
   
     The  aggregate  number of shares the Company has the  authority to issue is
120 million,  par value $.01 per share,  consisting of 90,000,000  common shares
and  30,000,000  undesignated  shares.  The Board of Directors of the Company is
authorized to establish from the undesignated  shares, by resolution adopted and
filed in the manner provided by law, one or more classes or series of shares, to
designate  each such class or series  (which may  include  but is not limited to
designation as additional  common  shares),  and to fix the relative  rights and
preferences  of each such class or series.  None of the  holders of any class or
series of the  Company's  capital  stock  have  preemptive  rights or a right to
cumulative voting.
    
Common Stock
   
     As of the date of this  Memorandum,  there  were  47,385,759  shares of the
Company's Common Stock issued and outstanding.  The Board of Directors may issue
additional  shares of Common Stock  without the consent of the holders of Common
Stock.
    
     Each  outstanding  share of Common  Stock is entitled to one vote except as
may be otherwise required under the terms of the MBCA. All outstanding shares of
Common Stock are fully paid and non-assessable.

     Holders of Common Stock are  entitled to receive  such  dividends as may be
declared by the directors out of funds legally available therefor,  and to share
pro rata in any  distributions  to holders of Common Stock upon  liquidation  or
otherwise. However, the Company has not paid cash dividends on its Common Stock,
and does not expect to pay such dividends in the foreseeable future.

     Under the provisions of the MBCA, which governs the actions of the Company,
an amendment to the Articles of  Incorporation  of the Company  generally may be
adopted by the affirmative vote of the holders of a majority of the voting power
of the shares present and entitled to vote at a  shareholders'  meeting at which
an amendment is proposed.  Under the statute,  a majority of the voting power of
the  shares  entitled  to  vote at a  meeting  is  generally  a  quorum  for the
transaction of business.  Accordingly,  it is possible that the affirmative vote
of shares in excess of 25 percent of the  outstanding  shares could authorize an

<PAGE>

amendment to the Company's  Articles of  Incorporation.  Under the Statute,  the
affirmative  vote of the holders of a majority of the voting power of all shares
entitled to vote is necessary to approve a plan of merger, a plan of exchange, a
sale  of  all  or  substantially  all  of the  assets  of  the  Company,  or its
dissolution.

Options and Warrants
   
     The Company has granted  options and warrants to purchase up to  15,948,603
shares of Common Stock to officers, directors, scientific advisors, consultants,
investors,  and financial advisors at exercise prices ranging from $.125 to $.90
per share.
    

        

Transfer Agent

     StockTrans Inc., Seven East Lancaster Avenue,  Ardmore,  PA is the transfer
agent for the Common Stock.

        

                              PLAN OF DISTRIBUTION

     All or a portion of the Shares offered by the Selling  Shareholders  hereby
may be  sold  from  time to time by the  Selling  shareholders  or by  pledgees,
donees,  transferees or other successors in interest.  Such sales may be made in
the over-the-counter  market or otherwise at prices and at terms then prevailing
or at  prices  related  to the  then  current  market  price,  or in  negotiated
transactions.  The Shares may be sold by one or more of the following means: (a)
ordinary  brokerage or market making  transactions and transactions in which the
broker or dealer  solicits  purchasers;  (b) block trades in which the broker or
dealer so engaged  will attempt to sell the Shares as agent but may position and
resell a portion of the block as principal to facilitate  the  transaction;  and
(c)  purchases by a broker or dealer as principal  and resales by such broker or
dealer for its account pursuant to this Prospectus.  In effecting sales, brokers
or dealers engaged by the Selling  Shareholders may arrange for other brokers or
dealers to participate. Brokers or dealers will receive commissions or discounts
from the Selling  Shareholders in amounts to be negotiated  immediately prior to
the  sales.  Such  brokers  or dealers  and any other  participating  brokers or
dealers may be deemed to be "underwriters"  within the meaning of the Securities
Act of 1933,  as amended,  in  connection  with such  sales.  In  addition,  any
securities  covered by this  Prospectus  which qualify for sale pursuant to Rule
144  under the Act may be sold  under  Rule 144  rather  than  pursuant  to this
Prospectus.

        

                                TABLE OF CONTENTS
   
Available Information........................................................2
Documents Incorporated By Reference..........................................2
Company Summary..............................................................3
Risk Factors.................................................................4
Principal and Selling Shareholders...........................................8
Description of Securities...................................................13
Plan of Distribution........................................................14
    

<PAGE>

                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

Item 14.  Other Expenses of Issuance and Distribution

The estimated expenses in connection with this offering are as follows:

Securities and Exchange Commission Filing Fee......................  $14,259
Legal Fees and Expenses............................................  $ 7,500
Accounting Fees and Expenses.......................................  $ 7,500
Printing...........................................................  $ 5,000
Miscellaneous......................................................  $   741
                                                                     -------
    Total Expenses.................................................  $35,000



Item 15.  Indemnification of Directors and Officers.

     Section 302A.521 of the Minnesota Business  Corporation Act provides that a
corporation  shall  indemnify  any person who was or is  threatened to be made a
party to any proceeding by reason of the former or present official  capacity of
such  person ,  against  judgments,  penalties  and  fines,  including,  without
limitation  , excise  taxes  assessed  against  such person  with  respect to an
employee benefit plan, settlements and reasonable expenses, including attorneys'
fees  and  disbursements,  incurred  by  such  person  in  connection  with  the
proceeding,  if, with respect to the acts or omissions of such person complained
of  in  the  proceeding  such  person  has  not  been   indemnified  by  another
organization or employee  benefit plan for the same expenses with respect to the
same acts or  omissions,  acted in good faith,  received  no  improper  personal
benefit and Section 302A.255 (which pertains to director conflicts of interest),
if applicable,  has been satisfied; in the case of a criminal proceeding, had no
reasonable cause to believe the conduct was unlawful; and in the case of acts or
omissions by a person in their official capacity for the corporation, reasonably
believed that the conduct was in the best  interests of the  corporation,  or in
the  case  of  acts  or  omissions  by  persons  in  their  capacity  for  other
organizations,  reasonably believed that the conduct was not opposed to the best
interests of the corporation.

     The Minnesota Business Corporation Act also permits Minnesota  corporations
in their Articles of Incorporation to limit or eliminate  personal  liability of
directors to the corporation or its shareholders for monetary damages for breach
of fiduciary duty;  however,  for bids any limitation or elimination of director
liability  for (i) a breach  of the  director's  duty of  loyalty,  (ii) acts or
omissions not in good faith or that involve intentional  misconduct or a knowing
violation of law, (iii) corporate  distributions  which are either illegal or in
contravention of restrictions in the Articles,  Bylaws or any agreement to which
the corporation is a party,  (iv) violations of Minnesota  securities  laws, (v)
any transaction from which the director derived an improper personal benefit, or
(vi) any act or omission  occurring prior to the effective date of the provision
in the corporation's Articles eliminating or limiting liability.

     Article 8 of the Registrant's Articles of Incorporation reads as follows:

     "To the fullest extend permitted by Chapter 302A,  Minnesota  Statutes,  as
the same  exists or may  hereafter  be amended,  a director of this  corporation
shall  not be  personally  liable to the  corporation  or its  shareholders  for
monetary damages for breach of fiduciary duty as a director."

     The Registrant's  Bylaws provide for the  indemnification of its directors,
officers,  employees and agents in accordance  with,  and to the fullest  extent
permitted by, Section  302A.521 of the Minnesota  Business  Corporation  Act, as
amended form time to time.

   
Item 16.  Exhibits.
    
     See Exhibit Index on page following signatures.


<PAGE>




Item 17.  Undertakings.

(a) The undersigned Registrant hereby undertakes:

    (1) To file,  during  any period in which it offers or sells  securities,  a
post-effective amendment to this registration statement to:

        (I)   Include  any  prospectus  required  by  section  10(a)(3) of the
              Securities  Act;  
        (II)  Reflect in the  prospectus  any facts or events arising after
              the effective date of the Registration  Statement (or the most
              recent  post-effective amendment  thereof)  which,  individually
              or  in  the  aggregate, represents a fundamental  change in the 
              information  set forth in the registration statement; and
        (III) Include any additional  material  information  with respect to
              the plan of distribution not previously  disclosed in the 
              Registration Statement  or any  material  change  to  such
              information  in the Registration Statement.

              Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not
              apply  if  the   information   required   to  be   included  in  a
              post-effective  amendment  by those  paragraphs  is  contained  in
              periodic reports file by the Registrant  pursuant to section 13 or
              section  15(d) of the  Securities  Exchange  Act of 1934  that are
              incorporated by reference in the Registration Statement.

    (2) That for  determining  liability  under the Securities Act of 1933, each
such post-effective amendment shall be deemed to be a new registration statement
relating to the securities offered therein,  and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

    (3) To remove from  registration by means of a post-effective  amendment any
of the securities that remain unsold at the termination of the offering.


(b) Insofar as indemnification  for liabilities arising under the Securities Act
of 1933 may be permitted to directors,  officers and controlling  persons of the
Registrant pursuant to the foregoing  provisions,  or otherwise,  the Registrant
has been advised that in the opinion of the Securities  and Exchange  Commission
such indemnification is against public policy as expressed in the Securities Act
of  1933  and is,  therefore,  unenforceable.  In the  event  that a  claim  for
indemnification  against  such  liabilities  (other  than  the  payment  by  the
Registrant of expenses  incurred or paid by a director,  officer or  controlling
person of the  Registrant  in the  successful  defense  of any  action,  suit or
proceeding)  is  asserted by such  director,  officer or  controlling  person in
connection with the securities being registered,  the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit  to a  court  of  appropriate  jurisdiction  the  question  whether  such
indemnification  by it is against  public policy as expressed in the  Securities
Act of 1933 and will be governed by the final adjudication of such issue.

(c)  The undersigned Registrant further undertakes that:

         (1) For purposes of determining  any liability under the Securities Act
    of 1933, the information  omitted from the form of prospectus  filed as part
    of this registration statement in reliance upon Rule 430A and contained in a
    form of prospectus filed by the registrant pursuant to Rule 424(b)(1) or (4)
    or  497(h)  under  the  Securities  Act  shall be  deemed to be part of this
    registration statement as of the time it was declared effective.

         (2)  For the purpose of determining  any liability under the Securities
              Act of 1933, each post-effective amendment that contains a form of
              prospectus  shall be  deemed  to be a new  registration  statement
              relating to the securities  offered  therein,  and the offering of
              such  securities  at that time  shall be deemed to be the  initial
              bona fide offering thereof.

(d) The  undersigned   Registrant   hereby  undertakes  that,  for  purposes  of
    determining  any liability  under the Securities Act of 1933, each filing of
    the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of
    the Securities  Exchange Act of 1934 (and, where applicable,  each filing of
    an employee  benefit  plan's annual report  pursuant to Section 15(d) of the
    Securities  Exchange Act of 1934) that is  incorporated  by reference in the
    Registration  Statement shall be deemed to be a new  registration  statement
    relating  to the  securities  offered  therein,  and  the  offering  of such
    securities at that time shall be deemed to be the initial bona fide offering
    thereof.


<PAGE>


                                   SIGNATURES
   
     In accordance  with the  requirements  of the  Securities  Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-3 and has duly caused this registration
statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized, in the City of St. Paul, State of Minnesota, on January 21, 1997.
    
                            Quantech Ltd.

                            By /s/ R. H. Joseph Shaw
                              R. H. Joseph Shaw,  Chief Executive Officer

                                POWER OF ATTORNEY

     Pursuant  to  the   requirements  of  the  Securities  Act  of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities  and on the dates  indicated.  Each person  whose  signature  to this
Registration  Statement  appears  below  hereby  constitutes  and appoints R. H.
Joseph Shaw and  Gregory G.  Freitag,  and each of them,  as his or her true and
lawful  attorney-in-fact and agent, with full power of substitution,  to sign on
his or her behalf  individually  and in the capacity stated below and to perform
any acts necessary to be done in order to file all amendments and post-effective
amendments  to this  Registration  Statement,  and any  and all  instruments  or
documents filed as part of or in connection with this Registration  Statement or
the  amendments  thereto,  and each of the  undersigned  does hereby  ratify and
confirm all that said  attorney-in-fact  and agent,  or his or her  substitutes,
shall do or cause to be done by virtue hereof.

Signatures                               Title

/s/R. H. Joseph Shaw                     Chief Executive Officer and
R. H. Joseph Shaw                        Chairman of the Board

/s/ Robert R. McKiel*                    Executive Vice President-Research
Robert R. McKiel                         and Development  and Director

/s/ Gregory G. Freitag                   Chief Financial Officer, Vice
Gregory G. Freitag                       President of Corporate Development
                                         and Secretary

/s/ James F. Lyons*                      Director
James F. Lyons

/s/ Richard W. Perkins*                  Director
Richard W. Perkins

/s/ Edward E. Strickland*                Director
Edward E. Strickland
   
*Pursuant to Power of Attorney previously filed:

               /s/R.H. Joseph Shaw          /s/Gregory G. Freitag    
               R.H. Joseph Shaw              Gregory G. Freitag


Dated: January 21, 1997
    

<PAGE>


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                  QUANTECH LTD.
                           EXHIBIT INDEX TO FORM SB-2

   
Exhibit
Number           Description

2.1   Plan of Reorganization, dated November 24, 1992, by and among Quantech
      Ltd. and Spectrum Diagnostics S.p.A. (incorporated by reference to Exhibit
      2.1 of the Registrant's Registration Statement on Form S-4; Reg. No.
      33-55356).
2.2   Amendment and Restatement Agreement and Plan of Merger dated January 20,
      1993 by and among Quantech Ltd., Spectrum Diagnostics S.p.A. and Spectrum
      Diagnostics Corp. (incorporated by reference to Exhibit 2.2 of the
      Registrant's Registration Statement on Form S-4; Reg. No. 33-55356).
3.1   Articles  of   Incorporation  of  Quantech  Ltd., as amended to date
3.2   Bylaws of Quantech Ltd. (incorporated by reference to Exhibit 3.2 of the
      Registrant's Registration Statement on Form S-4; Reg. No. 33-55356).
4.1   Form of Stock Certificate (incorporated by reference to Exhibit 4.1 of
      the Registrant's Registration Statement on Form S-4; Reg. No. 33-55356).
4.2   Form of Private Placement Warrant.                                     *
5.1   Opinion and Consent of Fredrikson & Byron, P.A.
10.1  Lease for office at 1419 Energy Park Drive, St. Paul, MN 55108
      (incorporated by reference to Exhibit 10.1 of the Registrant's
      Form 10-KSB for the Year Ended June 30, 1995).
10.2  Option Agreement with Ares-Serono, as amended (including license)
      assigned to Quantech Ltd. pursuant to the Merger (incorporated by 
      reference to Exhibit 10.2 of the Registrant's Registration Statement 
      on Form S-4; Reg. No. 33-55356).
10.3  Employment Agreement with R.H. Joseph Shaw (incorporated by reference to
      Exhibit 10.3 of the Registrant's Form 10-KSB for the Year Ended June 30,
      1995).
10.4  Employment Agreement with Robert M. McKiel (incorporated by reference to
      Exhibit 10.4 of the Registrant's Form 10-KSB for the Year Ended June 30,
      1995).
10.5  Letter of amendment to Ares-Serono License (incorporated by reference to
      Exhibit 10.6 of the Registrant's Form 10-KSB for the Year Ended June 30,
      1995).
10.6  Stock Option to purchase 1,246,000 shares by R.H. Joseph Shaw
      (incorporated by reference to Exhibit 10.12 of the Registrant's Form
      10-KSB for the Year Ended June 30, 1995).
10.7  Stock Option to purchase 830,841 shares by Robert M. McKiel (incorporated
      by reference to Exhibit 10.13 of the Registrant's Form 10-KSB for the 
      Year Ended June 30, 1995).
10.8  Employment Agreement with Gregory G. Freitag.                          *
22    Quantech has no subsidiaries.
23.1  Consent of Fredrikson & Byron, P.A. (included in Exhibit 5.1)
23.2  Consent of McGladrey & Pullen L.L.P.
24    Power of Attorney (included on signature page to Registration Statement)
* Previously filed.
    


   
                              ARTICLES OF AMENDMENT
                          OF ARTICLES OF INCORPORATION
                                OF QUANTECH LTD.

     The  undersigned,  being  the  Secretary  of  Quantech  Ltd.,  a  Minnesota
corporation,  (the  "Corporation"),  on behalf of the  Corporation,  does hereby
certify  that the  following  recitals  and  resolutions  were adopted at a duly
called  special  meeting of the  shareholders,  pursuant to Minnesota  Statutes,
Sections 302A.135 and 302A.139.

     WHEREAS,  the Board of Directors of the  Corporation  believes it is in the
best  interest of the  Corporation  to amend the  Articles of  Incorporation  to
increase  the number of  authorized  shares  from  60,000,000  Common  Shares to
120,000,000  shares  consisting  of  90,000,000  Common  Shares  and  30,000,000
undesignated  shares and has previously adopted similar recitals and resolutions
as those proposed here.

     IT IS HEREBY RESOLVED THAT,

     The shareholders,  in accordance with the  Corporation's  Bylaws, do hereby
approve amending the Corporation's Articles to increase the number of authorized
shares  from  60,000,000  Common  Shares to  120,000,000  shares  consisting  of
90,000,000 Common Shares and 30,000,000 undesignated shares.

     RESOLVED FURTHER, that Section 3.1 is hereby amended to read as follows:

                                   ARTICLE 3.1
                                  CAPITAL STOCK

     The  aggregate  number  of  shares  of all  classes  of  stock  which  this
corporation  shall have the authority to issue is One Hundred and Twenty Million
(120,000,000) shares, $.01 par value per share,  consisting of 90,000,000 Common
Shares  and  30,000,000  undesignated  shares.  The  Board of  Directors  of the
corporation  is  authorized  to  establish  from  the  undesignated  shares,  by
resolution  adopted and filed in the manner provided by law, one or more classes
or series of shares,  to designate  each such class or series (which may include
but is not limited to designation as additional shares of Common Stock),  and to
fix the relative rights and preferences of each such class or series.

     RESOLVED FURTHER,

     The corporation's  officers are hereby authorized to complete all documents
necessary  and make all filings  necessary to  effectuate  the  amendment to the
Corporation's  Articles of  Incorporation  and to record such  Amendment  in the
Corporation's official record books.

Dated and effective: November 25, 1996.

/s/ Gregory G. Freitag, Secretary


<PAGE>



                              ARTICLES OF AMENDMENT
                                     TO THE
                            ARTICLES OF INCORPORATION
                                       OF
                                  QUANTECH LTD.

     The  undersigned,  being  the  Secretary  of  Quantech  Ltd.,  a  Minnesota
corporation  (the  "Corporation"),  on behalf of the  Corporation,  does  hereby
certify  that the  following  recitals  and  resolutions  were adopted at a duly
called  special  meeting of the  shareholders,  pursuant to  Minnesota  Statutes
Sections 302A.135 and 302A.139:

                 WHEREAS,  the Board of Directors of the  Corporation  believes
         it is in the best  interests of the  Corporation  to amend the Articles
         of  Incorporation  to increase  the number of authorized  common stock
         shares  from  30,000,000  to 60,000,000 and has previously  adopted 
         similar recitals and resolutions as those proposed here;

         IT IS HEREBY RESOLVED THAT:

                  The shareholders, in accordance with the Corporation's Bylaws,
         do hereby approve amending the Corporation's  Articles of Incorporation
         to  increase  the  number  of  authorized   common  stock  shares  from
         30,000,000 to 60,000,000;

         RESOLVED FURTHER:

                  Section 3.1 is hereby amended to read:

                                   ARTICLE 3.1
                                  CAPITAL STOCK

                  The  aggregate  number of shares of all classes of stock which
         this  corporation  shall have the  authority to issue is Sixty  Million
         (60,000,000)  shares,  $.01 par value per share. The Board of Directors
         of the  corporation  is authorized to establish  from the  undesignated
         shares, by resolution  adopted and filed in the manner provided by law,
         one or more classes or series of shares,  to designate  each such class
         or series  (which may  include  but is not  limited to  designation  as
         additional shares of Common Stock),  and to fix the relative rights and
         preferences of each such class or series.

         RESOLVED FURTHER:

                  The  corporation's  officers are hereby authorized to complete
         all documents  necessary  and make all filings  necessary to effectuate
         the amendment to the  Corporation's  Articles of  Incorporation  and to
         record such Amendment in the Corporation's official record books.

Dated and effective September 28, 1995.

                                              /s/ George Vitalis, Secretary


<PAGE>



                            ARTICLES OF INCORPORATION
                                       OF
                                  QUANTECH LTD.


     The undersigned individual, being of full age, for the purpose of forming a
corporation  under and pursuant to Chapter 302A of the  Minnesota  Statutes,  as
amended, hereby adopts the following Articles of Incorporation:


                                ARTICLE 1 - NAME

         1.1)  The name of the corporation shall be Quantech, Ltd.


                          ARTICLE 2 - REGISTERED OFFICE

         2.1)  The registered office of the corporation is located at 1021
Bandana Boulevard East, Suite 212, St. Paul, Minnesota 55108.


                            ARTICLE 3 - CAPITAL STOCK

         3.1)  Authorized  Shares;  Establishment  of Classes  and  Series.  The
aggregate  number of shares the  corporation  has  authority  to issue  shall be
30,000,000 shares, which shall have a par value of $.01 per share solely for the
purpose  of a  statute  or  regulation  imposing  a tax or fee  based  upon  the
capitalization of the corporation,  and which shall consist of 15,000,000 shares
of Common Stock and 15,000,000  undesignated  shares.  The Board of Directors of
the  corporation is authorized to establish  from the  undesignated  shares,  by
resolution  adopted and filed in the manner provided by law, one or more classes
or series of shares,  to designate  each such class or series (which may include
but is not limited to designation as additional shares of Common Stock),  and to
fix the relative rights and preferences of each such class or series.

         3.2) Issuance of Shares.  The Board of Directors of the  corporation is
authorized  from  time to time to  accept  subscriptions  for,  issue,  sell and
deliver  shares of any class or series of the  corporation  to such persons,  at
such  times and upon such terms and  conditions  as the Board  shall  determine,
valuing all nonmonetary consideration and establishing a price in money or other
consideration,  or a minimum price,  or a general formula or method by which the
price will be determined.

         3.3) Issuance of Rights to Purchase  Shares.  The Board of Directors is
further authorized from time to time to grant and issue rights to subscribe for,
purchase,  exchange  securities for, or convert  securities into,  shares of the
corporation  of any  class  or  series,  and to fix the  terms,  provisions  and
conditions of such rights,  including  the exchange or  conversion  basis or the
price at which such shares may be purchased or subscribed for.



<PAGE>



         3.4)  Issuance  of Shares to Holders of  Another  Class or Series.  The
Board is further authorized to issue shares of one class or series to holders of
that  class or series or to holders  of  another  class or series to  effectuate
share dividends or splits.


                       ARTICLE 4 - RIGHTS OF SHAREHOLDERS

         4.1)  No  Preemptive  Rights.  No  shares  of any class or series of
the corporation  shall entitle the holders to any preemptive rights to subscribe
for or  purchase  additional  shares of that  class or series or any other class
or series of the corporation now or hereafter authorized or issued.

         4.2)  No Cumulative Voting Rights.  There shall be no cumulative voting
by the shareholders of the corporation.


                              ARTICLE 5 - DIRECTORS

         5.1)  The names of the person constituting the first Board of Directors
is as follows:

                  R. H. Joseph Shaw


          ARTICLE 6 - MERGER, EXCHANGE, SALE OF ASSETS AND DISSOLUTION

         6.1) Where approval of shareholders is required by law, the affirmative
vote of the  holders  of at least a majority  of the voting  power of all shares
entitled to vote shall be required to  authorize  the  corporation  (i) to merge
into or with one or more other  corporations,  (ii) to  exchange  its shares for
shares of one or more other  corporations,  (iii) to sell,  lease,  transfer  or
otherwise  dispose  of all or  substantially  all of its  property  and  assets,
including its good will, or (iv) to commence voluntary dissolution.


               ARTICLE 7 - AMENDMENT OF ARTICLES OF INCORPORATION

         7.1) After the  issuance of shares by the  corporation,  any  provision
contained in these Articles of Incorporation may be amended, altered, changed or
repealed  by the  affirmative  vote of the holders of at least a majority of the
voting  power of the shares  present and entitled to vote at a duly held meeting
or such greater  percentage  as may be otherwise  prescribed  by the laws of the
State of Minnesota.


                  ARTICLE 8 - LIMITATION OF DIRECTOR LIABILITY

         8.1)  To the  fullest  extent  permitted  by  Chapter  302A,  Minnesota
Statutes,  as the same exists or may  hereafter  be amended,  a director of this
corporation shall not be personally liable

                                      - 2 -

<PAGE>


to the corporation or its shareholders for monetary damages for breach of
fiduciary duty as a director.


                            ARTICLE 9 - INCORPORATOR

         9.1)  The name and mailing address of the incorporator are as follows:

                  Gregory G. Freitag
                  900 Second Avenue South
                  1100 International Centre
                  Minneapolis, Minnesota 55402


         IN WITNESS WHEREOF,  the undersigned  incorporator has hereunto set his
hand this 13th day of November, 1992.


                                           /s/ Gregory G. Freitag

                                      - 3 -
    



   

                            FREDRIKSON & BYRON, P.A.
                       900 Second Avenue South, Suite 1100
                          Minneapolis, Minnesota 55402

                            Telephone: (612) 347-7000
                            Facsimile: (612) 347-7077



                                January 21, 1997



Quantech Ltd.
1419 Energy Park Drive
St. Paul, Minnesota  55108

    Re:  Post-Effective Amendment No. 1 to Registration Statement No. 333-6809

Ladies/Gentlemen:

     We are acting as corporate  counsel to Quantech  Ltd.  (the  "Company")  in
connection  with the preparation  and filing of  Post-Effective  Amendment No. 1
(the "Amendment") on Form S-3 to Form SB-2  Registration  Statement No. 333-6809
(the "Registration Statement") relating to the registration under the Securities
Act of 1933, as amended (the "Act") of 49,021,530 shares of the Company's Common
Stock (the "Shares") to be sold by certain  shareholders,  including  11,940,103
shares  which  may  be  issued  upon  exercise  of  outstanding   warrants  (the
"Warrants").

     In acting as such counsel and for the purpose of rendering this opinion, we
have reviewed copies of the following, as presented to us by the Company:

         1.       The Company's Articles of Incorporation, as amended.

         2.       The Company's Bylaws, as amended.

         3.       Certain corporate resolutions of the Company's Board of 
                  Directors pertaining to the issuance by the Company of the
                  Shares.

         4.       The Registration Statement and the Amendment.

     Based on,  and  subject  to, the  foregoing  and upon  representations  and
information  provided by the Company or its  officers  or  directors,  it is our
opinion as of this date that:

         1.       The Shares are validly authorized by the Company's Articles 
                  of Incorporation, as amended.

         2.      The  Shares  have  been duly  authorized  and are,  or upon
                 payment therefor upon exercise of the Warrants will be, 
                 validly issued and  outstanding, fully paid and nonassessable.

     We hereby  consent  to the  filing of this  opinion  as an  exhibit  to the
Registration Statement and to the reference to our firm under the caption "Legal
Matters" included in the Registration Statement and the related Prospectus.

                                            Very truly yours,

                                            FREDRIKSON & BYRON, P.A.


                                            By  /s/ Timothy M. Heaney
                                                 Timothy M. Heaney



    






   


                       CONSENT OF INDEPENDENT ACCOUNTANTS


     We hereby consent to the incorporation by reference in this  Post-effective
Amendment number 1 to Form SB-2 Registration on Form S-3 Registration  Statement
of our report,  dated July 16, 1996,  relating to the  financial  statements  of
Quantech,  Ltd.,  which report  appears on page 25 of the annual  report on Form
10-KSB of Quantech, Ltd. for the year ended June 30, 1996.



                                              /s/ McGladrey & Pullen, LLP

                                              McGladrey & Pullen, LLP


Minneapolis, Minnesota
January 21, 1997


    



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