<PAGE>
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
(Rule 13d-102)
INFORMATION TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND
AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b)
(Amendment No. 3 )/1/
MAGAININ PHARMACEUTICALS, INC.
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(Name of Issuer)
Common Stock $.002 par value
--------------------------------------------------------------
(Title of Class of Securities)
559036108
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(CUSIP Number)
March 31, 2000
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(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[ ] Rule 13d-1 (b)
[ ] Rule 13d-1 (c)
[X] Rule 13d-1 (d)
__________
/1/ The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
(Continued on following page(s))
Page 1 of 13 Pages
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CUSIP NO. 559036108 13G Page 2 of 13 Pages
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
HealthCare Ventures V, L.P.
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
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SEC USE ONLY
3
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CITIZENSHIP OR PLACE OF ORGANIZATION
4
Delaware
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SOLE VOTING POWER
5
NUMBER OF
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
868,250
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
868,250
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
868,250
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.2%
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
PN
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*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP NO. 559036108 13G Page 3 of 13 Pages
---------
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
HealthCare Ventures V, L.P.
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Delaware
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
868,250
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
868,250
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
868,250
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.2%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
PN
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*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP NO. 559036108 13G Page 4 of 13 Pages
---------
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
James H. Cavanaugh, Ph.D.
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
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SEC USE ONLY
3
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CITIZENSHIP OR PLACE OF ORGANIZATION
4
United States
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SOLE VOTING POWER
5
NUMBER OF
2,321
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
907,147
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING 2,321
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
907,147
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
909,468
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CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.4%
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
IN
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP NO. 559036108 13G Page 5 of 13 Pages
---------
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
Harold R. Werner
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
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SEC USE ONLY
3
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CITIZENSHIP OR PLACE OF ORGANIZATION
4
United States
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SOLE VOTING POWER
5
NUMBER OF
4,859
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
907,147
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING 4,859
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
907,147
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
912,006
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CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.4%
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
IN
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*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP NO. 559036108 13G Page 6 of 13 Pages
---------
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
William Crouse
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
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SEC USE ONLY
3
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CITIZENSHIP OR PLACE OF ORGANIZATION
4
United States
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
907,147
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
907,147
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
907,147
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.3%
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
IN
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP NO. 559036108 13G Page 7 of 13 Pages
---------
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NAMES OF REPORTING PERSONS.
1 I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
John W. Littlechild
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
2 (a) [_]
(b) [_]
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SEC USE ONLY
3
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CITIZENSHIP OR PLACE OF ORGANIZATION
4
United States
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
907,147
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
907,147
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
907,147
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10 (SEE INSTRUCTIONS)
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
3.3%
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
12
IN
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*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
Page 8 of 13
Item 1.
(a) Name of Issuer:
Magainin Pharmaceuticals, Inc.
(b) Address of Issuer's Principal Executive Offices:
5110 Campus Drive
Plymouth Meeting, Pennsylvania 19462
Item 2.
(a) Name of Person Filing:/1/
HealthCare Ventures V, L.P. ("HCV V"), HealthCare Partners V, L.P.
("HCP V"), Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse.
See attached Exhibit A which is a copy of their agreement in writing
to file this statement on behalf of each of them./2/
(b) Address of Principal Business Office or, if none, Residence:
The business address for HCV V, HCP V, Dr. Cavanaugh and Messrs.
Werner and Crouse is 44 Nassau Street, Princeton, New Jersey 08542.
The business address for Mr. Littlechild is One Kendall Square,
Building 300, Cambridge, Massachusetts 02139.
(c) Citizenship:
HCV V and HCP V are limited partnerships organized under the laws of
the State of Delaware. Dr. Cavanaugh and Messrs. Werner, Littlechild
and Crouse are each United States citizens.
(d) Title of Class of Securities:
Common Stock, par value $.002 ("Shares").
(e) CUSIP Number:
559036108
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/1/ Mark Leschly withdrew as a general partner of HCP V, effective July 1,
1999.
/2/ Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are general
partners of HCP V, which is the general partner of HCV V, the record holder of
the 868,250 shares of Issuer's Common Stock reported hereto.
<PAGE>
Page 9 of 13
Item 3. If this statement is filed pursuant to Rule 13d-1(b) or (c), or 13d-
2(b), check whether the person filing is a:
Inapplicable.
Item 4. Ownership.
(a) Amount Beneficially Owned:
As of March 31, 2000: HCV V and HCP V beneficially owned 868,250
Shares of Issuer's Common Stock; Dr. Cavanaugh beneficially owned
909,468 Shares of the Issuer's Securities, consisting of 870,571
Shares of Issuer's Common Stock and immediately exercisable warrants
to purchase 38,897 Shares of Issuer's Common Stock/3/; Mr. Werner
beneficially owned 912,006 Shares of Issuer's Securities, consisting
of 873,109 Shares of Issuer's Common Stock and immediately exercisable
warrants to purchase 38,897 Shares of Issuer's Common Stock/3/;
Messrs. Littlechild and Crouse each beneficially owned 907,147 Shares
of Issuer's Securities, consisting of 868,250 Shares of Issuer's
Common Stock and immediately exercisable warrants to purchase 38,897
Shares of Issuer's Common Stock/3/.
(b) Percent of Class:
As of March 31, 2000: the 868,250 Shares of Issuer's Securities
beneficially owned by each of HCV V and HCP V constitute 3.2% of
Issuer's Shares outstanding; the 907,147 Shares of Issuers Securities
beneficially owned by Messrs. Crouse and Littlechild constitute 3.3%
of Issuer's Shares outstanding; the 909,468 Shares of Issuer's
Securities beneficially owned by Dr. Cavanaugh constitutes 3.4% of
Issuer's Shares outstanding; and the 912,006 Shares of Issuer's
Securities beneficially owned by Mr. Werner constitute 3.4% of
Issuer's Shares outstanding.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
- -------------------
/3/ The immediately exercisable warrants to purchase 38,897 Shares of
Issuer's Common Stock are held by HealthCare Ventures II, L.P. ("HCV II"), of
which HealthCare Partners II, L.P. ("HCP II") is a general partner
(collectively, the "Warrants"). Dr. Cavanaugh and Messrs. Werner, Littlechild
and Crouse are general partners of HCP II. The exercise price of such Warrants
is $8.00 per share.
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Page 10 of 13
Dr. Cavanaugh has the sole power to vote or direct the vote of
the 2,321 Shares of Issuer's Common Stock beneficially owned by
him.
Mr. Werner has the sole power to vote or direct the vote of the
4,859 Shares of Issuer's Common Stock beneficially owned by him.
(ii) shared power to vote or to direct the vote:
HCV V, HCP V, Dr. Cavanaugh and Messrs. Werner, Littlechild and
Crouse share the power to vote or direct the vote of those Shares
owned by HCV V./4/
(iii) sole power to dispose or to direct the disposition of:
Dr. Cavanaugh has the sole power to dispose of or direct the
disposition of the 2,321 Shares of Issuer's Common Stock
beneficially owned by him.
Mr. Werner has the sole power to dispose of or direct the
disposition of the 4,859 Shares of Issuer's Common Stock
beneficially owned by him.
(iv) shared power to dispose of or to direct the disposition of:
HCV V, HCP V, Dr. Cavanaugh and Messrs. Werner, Littlechild and
Crouse share the power to dispose of or direct the disposition of
those Shares owned by HCV V./5/
Item 5. Ownership of Five Percent or less of a Class:
This statement is being filed to report the fact that as of the
date hereof HCV V, HCP V, Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse have ceased to be the beneficial owners of
more than 5% of a class of securities of the Issuer.
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/4/ Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power
to vote or direct the vote of the Shares of Issuer's Common Stock underlying the
Warrants held by HCV II.
/5/ Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power
to dispose of or direct the disposition of the Shares of Issuer's Common Stock
underlying the Warrants held by HCV II.
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Page 11 of 13
Item 6. Ownership of More than Five Percent on Behalf of Another Person:
Inapplicable.
Item 7. Identification and Classification of the Subsidiary Which Acquired the
Security Being Reported on by the Parent Holding Company:
Inapplicable.
Item 8. Identification and Classification of Members of the Group:
Inapplicable.
Item 9. Notice of Dissolution of Group:
Inapplicable.
Item 10. Certification:
Inapplicable.
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Page 12 of 13
SIGNATURES
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Dated: April 10, 2000 HealthCare Ventures V, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners V, L.P.,
By: s/ Jeffrey Steinberg
________________________________________________
Jeffrey Steinberg
Administrative Partner
Dated: April 10, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By: s/ Jeffrey Steinberg
________________________________________________
Jeffrey Steinberg
Administrative Partner
Dated: April 10, 2000 By: *
Princeton, New Jersey ------------------------------------------------
James H. Cavanaugh, Ph.D.
Dated: April 10, 2000 By: *
Princeton, New Jersey ------------------------------------------------
Harold R. Werner
Dated: April 10, 2000 By: *
Cambridge, Massachusetts ------------------------------------------------
John W. Littlechild
Dated: April 10, 2000 By: *
Princeton, New Jersey ------------------------------------------------
William Crouse
__________________________
*Signed by Jeffrey Steinberg as Attorney-in-Fact pursuant to the Power of
Attorney filed previously and incorporated herein by reference.
<PAGE>
Page 13 of 13
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13G and any future amendments thereto
reporting each of the undersigned's ownership of securities of Magainin
Pharmaceuticals, Inc. and hereby affirm that such Schedule 13G is being filed on
behalf of each of the undersigned.
Dated: April 10, 2000 HealthCare Ventures V, L.P.
Princeton, New Jersey by its General Partner, HealthCare Partners V, L.P.,
By: s/ Jeffrey Steinberg
_____________________________________________
Jeffrey Steinberg
Administrative Partner
Dated: April 10, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By: s/ Jeffrey Steinberg
_____________________________________________
Jeffrey Steinberg
Administrative Partner
Dated: April 10, 2000 By: *
Princeton, New Jersey ---------------------------------------------
James H. Cavanaugh, Ph.D.
Dated: April 10, 2000 By: *
Princeton, New Jersey ---------------------------------------------
Harold R. Werner
Dated: April 10, 2000 By: *
Cambridge, Massachusetts ---------------------------------------------
John W. Littlechild
Dated: April 10, 2000 By: *
Princeton, New Jersey ---------------------------------------------
William Crouse
___________________
*Signed by Jeffrey Steinberg as Attorney-in-Fact
