<PAGE>
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
(Rule 13d-102)
INFORMATION TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND
AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b)
(Amendment No. 2 )(1)
MAGAININ PHARMACEUTICALS, INC.
---------------------------------------------------------
(Name of Issuer)
Common Stock $.002 par value
----------------------------------------------------------
(Title of Class of Securities)
559036108
----------------------------------------------------------
(CUSIP Number)
December 31, 1999
----------------------------------------------------------
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
|_| Rule 13d-1 (b)
|_| Rule 13d-1 (c)
|X| Rule 13d-1 (d)
- ----------
(1) The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
(Continued on following page(s))
Page 1 of 15 Pages
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 2 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Ventures V, L.P.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,323,500
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,323,500
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,323,500
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.6%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
PN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 3 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Partners V, L.P.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,323,500
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,323,500
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,323,500
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.6%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
PN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 4 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
James H. Cavanaugh, Ph. D.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
2,321
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,362,397
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
2,321
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,362,397
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,364,718
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.8%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 5 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Harold R. Werner
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
4,859
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,362,397
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
4,859
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,362,397
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,367,256
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.8%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 6 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
William Crouse
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,362,397
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,362,397
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,362,397
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.8%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
- ------------------------------- -----------------------------
CUSIP NO. 559036108 13G Page 7 of 15 Pages
---------------
- ------------------------------- -----------------------------
- --------------------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
John W. Littlechild
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF
SHARES ----------------------------------------------------
BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY
EACH 2,362,397
REPORTING
PERSON ----------------------------------------------------
WITH
7 SOLE DISPOSITIVE POWER
----------------------------------------------------
8 SHARED DISPOSITIVE POWER
2,362,397
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,362,397
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
[ ]
- --------------------------------------------------------------------------------
11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9
8.8%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
* SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE>
Page 8 of 15
Item 1.
(a) Name of Issuer:
Magainin Pharmaceuticals, Inc.
(b) Address of Issuer's Principal Executive Offices:
5110 Campus Drive
Plymouth Meeting, Pennsylvania 19462
Item 2.
(a) Name of Person Filing:(1)
HealthCare Ventures V, L.P. ("HCV V"), HealthCare Partners V,
L.P. ("HCP V"), Dr. Cavanaugh and Messrs. Werner, Littlechild
and Crouse. See attached Exhibit A which is a copy of their
agreement in writing to file this statement on behalf of each
of them.(2)
(b) Address of Principal Business Office or, if none, Residence:
The business address for HCV V, HCP V, Dr. Cavanaugh and
Messrs. Werner and Crouse is 44 Nassau Street, Princeton, New
Jersey 08542. The business address for Mr. Littlechild is One
Kendall Square, Building 300, Cambridge, Massachusetts 02139.
(c) Citizenship:
HCV V and HCP V are limited partnerships organized under the
laws of the State of Delaware. Dr. Cavanaugh and Messrs.
Werner, Littlechild and Crouse are each United States
citizens.
(d) Title of Class of Securities:
Common Stock, par value $.002 ("Shares").
(e) CUSIP Number:
559036108
- -------------------------
(1) Mark Leschly withdrew as a general partner of HCP V, effective
July 1, 1999.
(2) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are
general partners of HCP V, which is the general partner of HCV V,
the record holder of the 2,323,500 shares of Issuer's Common Stock
reported hereto.
<PAGE>
Page 9 of 15
Item 3. If this statement is filed pursuant to Rule 13d-1(b) or (c),
or 13d-2(b), check whether the person filing is a:
Inapplicable.
Item 4. Ownership.
(a) Amount Beneficially Owned:
As of December 31, 1999: HCV V and HCP V beneficially owned
2,323,500 Shares of Issuer's Common Stock; Dr. Cavanaugh
beneficially owned 2,328,359 Shares of the Issuer's
Securities, consisting of 2,325,821 Shares of Issuer's Common
Stock and immediately exercisable warrants to purchase 38,897
Shares of Issuer's Common Stock(3); Mr. Werner beneficially
owned 2,367,256 Shares of Issuer's Securities, consisting of
2,328,359 Shares of Issuer's Common Stock and immediately
execisable warrants to purchase 38,897 Shares of Issuer's
Common Stock(2); Messrs. Littlechild and Crouse each
beneficially owned 2,362,397 Shares of Issuer's Securities,
consisting of 2,323,500 Shares of Issuer's Common Stock and
immediately exercisable warrants to purchase 38,897 Shares of
Issuer's Common Stock(3).
(b) Percent of Class:
As of December 31, 1999: the 2,323,500 Shares of Issuer's
Securities beneficially owned by each of HCV V and HCP V
constitute 8.6.% of Issuer's Shares outstanding; the 2,362,397
Shares of Issuers Securities beneficially owned by Messrs.
Crouse and Littlechild constitute 8.8% of Issuer's Shares
outstanding; the 2,364,718 Shares of Issuer's Securities
beneficially owned by Dr. Cavanaugh constitute 8.8% of
Issuer's Shares outstanding; and the 2,367,256 Shares of
Issuer's Securities beneficially owned by Mr. Werner
constitute 8.8% of Issuer's Shares outstanding.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
- -----------------------
(3) The immediately exercisable warrants to purchase 38,897 Shares of
Issuer's Common Stock are held by HealthCare Ventures II, L.P.
("HCV II"), of which HealthCare Partners II, L.P. ("HCP II") is a
general partner (collectively, the "Warrants"). Dr. Cavanaugh and
Messrs. Werner, Littlechild and Crouse are general partners of HCP
II. The exercise price of such Warrants is $8.00 per share .
<PAGE>
Page 10 of 15
(i) sole power to vote or to direct the vote:
Dr. Cavanaugh has the sole power to vote or direct
the vote of the 2,321 Shares of Issuer's Common Stock
beneficially owned by him.
Mr. Werner has the sole power to vote or direct the
vote of the 4,859 Shares of Issuer's Common Stock
beneficially owned by him.
(ii) shared power to vote or to direct the vote:
HCV V, HCP V, Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse share the power to vote or
direct the vote of those Shares owned by HCV V.(3)
(iii) sole power to dispose or to direct the disposition of:
Dr. Cavanaugh has the sole power to dispose of or
direct the disposition of the 2,321 Shares of
Issuer's Common Stock beneficially owned by him.
Mr. Werner has the sole power to dispose of or direct
the disposition of the 4,859 Shares of Issuer's
Common Stock beneficially owned by him.
(iv) shared power to dispose of or to direct the
disposition of:
HCV V, HCP V, Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse share the power to dispose of
or direct the disposition of those Shares owned by
HCV V.(4)
Item 5. Ownership of Five Percent or less of a Class:
Inapplicable.
Item 6. Ownership of More than Five Percent on Behalf of Another
Person:
Inapplicable.
- ----------------------
(3) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power to
vote or direct the vote of the Shares of Issuer's Common Stock underlying
the Warrants held by HCV II.
(4) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power to
dispose of or direct the disposition of the Shares of Issuer's Common Stock
underlying the Warrants held by HCV II.
<PAGE>
Page 11 of 15
Item 7. Identification and Classification of the Subsidiary Which
Acquired the Security Being Reported on by the Parent Holding
Company:
Inapplicable.
Item 8. Identification and Classification of Members of the Group:
Inapplicable.
Item 9. Notice of Dissolution of Group:
Inapplicable.
Item 10. Certification:
Inapplicable.
<PAGE>
Page 12 of 15
SIGNATURES
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is
true, complete and correct.
Dated: February 11, 2000 HealthCare Ventures V, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners V, L.P.,
By: /s/ Jeffrey Steinberg
--------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
--------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
James H. Cavanaugh, Ph.D.
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
Harold R. Werner
Dated: February 11, 2000 By: *
Cambridge, Massachusetts ----------------------------
John W. Littlechild
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
William Crouse
--------------------------
*Signed by Jeffrey Steinberg as Attorney-in-Fact pursuant to the Power of
Attorney filed previously and incorporated herein by reference.
<PAGE>
Page 13 of 15
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13G and any future amendments thereto
reporting each of the undersigned's ownership of securities of Magainin
Pharmaceuticals, Inc. and hereby affirm that such Schedule 13G is being
filed on behalf of each of the undersigned.
Dated: February 11, 2000 HealthCare Ventures V, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners V, L.P.,
By: /s/ Jeffrey Steinberg
--------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
--------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
James H. Cavanaugh, Ph.D.
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
Harold R. Werner
Dated: February 11, 2000 By: *
Cambridge, Massachusetts ----------------------------
John W. Littlechild
Dated: February 11, 2000 By: *
Princeton, New Jersey ----------------------------
William Crouse
-------------------
*Signed by Jeffrey Steinberg as Attorney-in-Fact
<PAGE>
Page 14 of 15
SIGNATURES
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is
true, complete and correct.
Dated: February 11, 2000 HealthCare Ventures V, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners V, L.P.,
By:
----------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By:
----------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
James H. Cavanaugh, Ph.D.
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
Harold R. Werner
Dated: February 11, 2000 By:
Cambridge, Massachusetts ----------------------------
John W. Littlechild
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
William Crouse
--------------------------
*Signed by Jeffrey Steinberg as Attorney-in-Fact pursuant to the Power of
Attorney filed previously and incorporated herein by reference.
<PAGE>
Page 15 of 15
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13G and any future amendments thereto
reporting each of the undersigned's ownership of securities of Magainin
Pharmaceuticals, Inc. and hereby affirm that such Schedule 13G is being
filed on behalf of each of the undersigned.
Dated: February 11, 2000 HealthCare Ventures V, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners V, L.P.,
By:
----------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 HealthCare Partners V, L.P.
Princeton, New Jersey
By:
----------------------------
Jeffrey Steinberg
Administrative Partner
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
James H. Cavanaugh, Ph.D.
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
Harold R. Werner
Dated: February 11, 2000 By:
Cambridge, Massachusetts ----------------------------
John W. Littlechild
Dated: February 11, 2000 By:
Princeton, New Jersey ----------------------------
William Crouse
-------------------
*Signed by Jeffrey Steinberg as Attorney-in-Fact
