GENTA INCORPORATED /DE/
SC 13D/A, 1997-09-18
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 2)*

                               Genta Incorporated
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                  372 45 M 20 7
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:
David R. Walner, Esq.                                    Monica C. Lord, Esq.
Paramount Capital Asset                                  Kramer, Levin,
   Management, Inc.                                        Naftalis & Frankel
787 Seventh Avenue                                       919 Third Avenue
New York, NY 10019                                       New York, NY  10022
(212) 554-4372                                           (212) 715-9100

   (Name, Address and Telephone Number of Person Authorized to Receive Notices
                              and Communications)

                               September 11, 1997
- --------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:     [_]

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).
                               Page 1 of 9 Pages


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 2 of 9 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Paramount Capital Asset Management, Inc.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 13,966,335**
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          13,966,335**
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           13,966,335**
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           76.2%  (40.6% of the outstanding voting power)***
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           CO
- -------------------------------------------------------------------------------
** Does not include shares of Common Stock (the "Note Interest  Common  Shares")
issuable upon  conversion of the Series D Convertible  Preferred  Stock issuable
upon  conversion of the interest on the 12% Senior  Secured  Convertible  Bridge
Notes. At August 31, 1997,  Paramount  Capital Asset  Management,  Inc. may have
been  deemed  beneficially  to own  (within  the meaning of Rule 13d-3 under the
Securities  Exchange  Act of 1934,  as amended)  374,039  Note  Interest  Common
Shares. 
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted to a vote of  stockholders  of the Issuer.  As of September  16, 1997,
Paramount  Capital  Asset  Management,  Inc. may be deemed  beneficially  to own
(within the meaning of Rule 13d-3 under the Securities  Exchange Act of 1934, as
amended)  40.6% of the  aggregate  voting power of the Common Stock and Series D
Preferred Stock outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 3 of 9 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Aries Domestic Fund, L.P.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 4,883,643**
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          4,883,643**
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           4,883,643**
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           26.7% (14.2% of the outstanding voting power)***
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           PN
- -------------------------------------------------------------------------------
** Does not include Note Interest  Common Shares.  At August 31, 1997, the Aries
Domestic Fund, L.P. may have been deemed beneficially to own (within the meaning
of Rule 13d-3 under the  Securities  Exchange Act of 1934,  as amended)  130,649
Note Interest Common Shares.  
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted to a vote of stockholders of the Issuer. As of September 16, 1997, the
Aries Domestic Fund, L.P. may be deemed  beneficially to own (within the meaning
of Rule 13d-3 under the  Securities  Exchange Act of 1934, as amended)  14.2% of
the  aggregate  voting  power of the Common  Stock and Series D Preferred  Stock
outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 4 of 9 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           The Aries Trust
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Cayman Islands

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 9,082,692**
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          9,082,692**
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           9,082,692**
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           49.5% (26.4% of the outstanding voting power)***
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           OO (see Item 2)
- -------------------------------------------------------------------------------
** Does not include Note Interest  Common Shares.  At August 31, 1997, The Aries
Trust may have been deemed beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934,  as amended)  243,390 Note Interest
Common Shares.
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted to a vote of stockholders of the Issuer. As of September 16, 1997, The
Aries Trust may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934, as amended)  26.4% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 5 of 9 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Lindsay A Rosenwald, M.D.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 13,966,335**
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          13,966,335**
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           13,966,335**
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           76.2% (40.6% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           IN
- -------------------------------------------------------------------------------
** Does not include Note Interest Common Shares. At August 31, 1997,  Lindsay A.
Rosenwald,  M.D. may have been deemed beneficially to own (within the meaning of
Rule 13d-3 under the Securities  Exchange Act of 1934, as amended)  374,039 Note
Interest Common Shares.  
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted to a vote of  stockholders  of the Issuer.  As of September  16, 1997,
Lindsay A. Rosenwald, M.D. may be deemed beneficially to own (within the meaning
of Rule 13d-3 under the  Securities  Exchange Act of 1934, as amended)  40.6% of
the  aggregate  voting  power of the Common  Stock and Series D Preferred  Stock
outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 6 of 9 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Mr. Michael S. Weiss
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [x]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           PF (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          16,644
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 None
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   16,644 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          None
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           16,644
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.4% (less than 0.1% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           IN
- -------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the Issuer.  As of September 16, 1997,  Mr. Michael S.
Weiss may be deemed  beneficially to own (within the meaning of Rule 13d-3 under
the Securities Exchange Act of 1934, as amended) less than 0.1% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>


                                  SCHEDULE 13D

         This Amendment No. 2 amends and  supplements the following Items of the
Reporting  Persons'  Statement on Schedule  13D,  dated  February  24, 1997,  as
amended to date, (the "Schedule").

ITEM 4. PURPOSE OF TRANSACTION.

         The  information  contained in Item 4 to the Schedule is hereby amended
and supplemented to read in its entirety as follows:

         The Filing Persons  acquired  securities of the Issuer as an investment
in the Issuer.  Except as indicated  in this  Schedule  13D, the Filing  Persons
currently  have no plans or proposals that relate to, or would result in, any of
the matters  described  in  subparagraphs  (a) through (j) of Item 4 of Schedule
13D.  Pursuant to Section 7.20 of the Note and Warrant Purchase  Agreement,  the
Aries  Reporting  Persons have the right to designate  nominees  constituting  a
majority of the members of the Board of Directors of the Issuer. Thomas H. Adams
resigned  from the Board of Directors  of the Issuer,  on which he had served as
Chairman of the Board of Directors,  and the Aries Reporting Persons  designated
Mr.  Weiss as a  nominee  for  Director  and he was  appointed  by the Board and
elected Interim Chairman of the Issuer's Board of Directors. David R. Walner, an
Associate  Director of Paramount  Capital,  Inc.  and an Associate  Director and
Secretary of Paramount Capital,  was appointed Secretary of the Issuer on May 5,
1997. On September 11, 1997, the Aries  Reporting  Persons  designated  Glenn L.
Cooper,  M.D.,  Donald G. Drapkin,  Bobby W. Sandage,  Jr.,  Ph.D. and Andrew J.
Stein as nominees to the Board of Directors of the Company  (the  "Board").  Mr.
Weiss  stepped  down as  Interim  Chairman  and the Board  elected  Mr.  Drapkin
Chairman and Mr. Weiss Vice Chairman.  The Reporting Persons have also discussed
with management of the Issuer, and are assisting the Issuer in, the hiring of an
individual  to fill the  present  vacancy  in the  position  of Chief  Executive
Officer for the Issuer. In connection with the Loan and the related transactions
(collectively,  the  "Transactions"),  the Issuer amended its Shareholder Rights
Agreement  (the  "Plan")  dated as of October 1, 1993,  to provide that the Plan
would not be applicable  to the Aries  Reporting  Persons and the  Transactions.
Aries Trust and Aries Domestic  entered into a Line of Credit Agreement with the
Issuer pursuant to which Aries Trust and Aries Domestic provided the Issuer with
a  line  of  credit  of  up to  $500,000,  which  subsequently  was  repaid,  in
consideration for warrants (the "Line of Credit Warrants") in the forms filed as
Exhibits N and O to  Amendment  No. 1 to Schedule  13D dated July 24,  1997,  to
purchase  50,000 shares of Common Stock of the Issuer  exerciseable at $2.50 per
share,  subject to adjustment upon the occurrence of certain events.  The Filing
Persons may from time to time acquire,  or dispose of, Common Stock and/or other
securities  of the  Issuer  if and when  they deem it  appropriate.  The  Filing
Persons may formulate other purposes, plans or proposals relating to any of such
securities  of the  Issuer to the  extent  deemed  advisable  in light of market
conditions, investment policies and other factors.


                               Page 7 of 9 Pages

<PAGE>

ITEM 5. INTEREST IN SECURITIES OF ISSUER.

         The  information  contained in Item 5 to the Schedule is hereby amended
and supplemented to read in its entirety as follows:

          (a)  As of September 16, 1997,  Dr.  Rosenwald and Paramount  Capital,
               through the  acquisitions  of securities by Aries Trust and Aries
               Domestic,  may be deemed beneficially to own 13,966,335 shares or
               76.2%  of the  Issuer's  Common  Stock  (not  including  the Note
               Interest Common Shares), and Aries Domestic,  Aries Trust and Mr.
               Weiss may be deemed  beneficially to own the following  number of
               shares of Common  Stock (in each  case,  not  including  any Note
               Interest Common Shares):


                Aries Domestic                     4,883,643
                Aries Trust                        9,082,692
                Mr. Weiss                             16,644

               Pursuant to Rule 13d-4 promulgated under the Securities  Exchange
               Act of 1934, as amended,  the Filing Persons disclaim  beneficial
               ownership  of all the Common Stock  except the  Purchased  Common
               Stock.  Pursuant to Rule 13d-4  promulgated  under the Securities
               Exchange Act of 1934, as amended, the Aries Reporting Persons and
               Mr. Weiss each disclaim  beneficial  ownership of all  securities
               held by the other.

               The outstanding  shares of Series D Preferred Stock of the Issuer
               are entitled to vote together with the holders of Common Stock on
               all matters submitted to a vote of stockholders of the Issuer. As
               of September 16, 1997, the Aries Reporting  Persons may be deemed
               beneficially  to own  (within the meaning of Rule 13d-3 under the
               Securities  Exchange  Act  of  1934,  as  amended)  40.6%  of the
               aggregate voting power of the Common Stock and Series D Preferred
               Stock   outstanding  (not  including  the  Note  Interest  Common
               Shares).

          (b)  Dr. Rosenwald and Paramount Capital share the power to vote or to
               direct the vote, to dispose or to direct the disposition of those
               shares owned by each of Aries Domestic and Aries Trust. Mr. Weiss
               has the sole power to direct the vote and to dispose or to direct
               the disposition of the shares that he owns.

          (c)  The Reporting Persons have not engaged in any transactions in the
               Common  Stock of the  Issuer  in the past 60 days,  except to the
               extent  that the  accrual of  interest  on the Notes  pursuant to
               their terms may be deemed a transaction.

          (d)  & (e) Not applicable.


                               Page 8 of 9 Pages


<PAGE>

                                   SIGNATURES

         After  reasonable  inquiry and to the best  knowledge and belief of the
undersigned,  the  undersigned  certify that the  information  set forth in this
statement is true, complete and correct.

                    PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   September 18, 1997
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President

                                 ARIES DOMESTIC FUND, L.P.
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   September 18, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


                                 THE ARIES TRUST
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   September 18, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


Dated:   September 18, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.



Dated:   September 18, 1997
         New York, NY             By: /s/ Michael S. Weiss
                                     ---------------------------------------
                                    Mr. Michael S. Weiss


                               Page 9 of 9 Pages



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