GENTA INCORPORATED /DE/
SC 13D/A, 1997-07-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*

                               Genta Incorporated
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
                         (Title of Class of Securities)

                                  372 45 M 20 7
                                 (CUSIP Number)

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:
David R. Walner, Esq.                                    Monica C. Lord, Esq.
Paramount Capital Asset                                  Kramer, Levin,
   Management, Inc.                                        Naftalis & Frankel
787 Seventh Avenue                                       919 Third Avenue
New York, NY 10019                                       New York, NY  10022
(212) 554-4372                                           (212) 715-9100

   (Name, Address and Telephone Number of Person Authorized to Receive Notices
                              and Communications)

                                  July 30, 1997
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:     [_]

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).
                               Page 1 of 13 Pages




<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 2 of 13 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Paramount Capital Asset Management, Inc.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 13,966,335
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          13,966,335
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           13,966,335
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           76.6%  (40.2% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           CO
- -------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer. As of July 24, 1997,  Paramount Captal Asset
Management,  Inc. may be deemed  beneficially to own (within the meaning of Rule
13d-3  under the  Securities  Exchange  Act of 1934,  as  amended)  40.2% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 3 of 13 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Aries Domestic Fund, L.P.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 4,883,643
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          4,883,643
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           4,883,643
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           26.8% (14.1% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           PN
- -------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the Issuer.  As of July 24, 1997,  the Aries  Domestic
Fund,  L.P. may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934, as amended)  14.1% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 4 of 13 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           The Aries Trust
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Cayman Islands

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 9,082,692
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          9,082,692
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           9,082,692
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           49.8% (26.1% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           OO (see Item 2)
- -------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of July 24, 1997, The Aries Trust may be
deemed  beneficially  to own  (within  the  meaning  of  Rule  13d-3  under  the
Securities Exchange Act of 1934, as amended) 26.1% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 5 of 13 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Lindsay A Rosenwald, M.D.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 13,966,335
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          13,966,335
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           13,966,335
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           76.6% (40.2% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           IN
- -------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of July 24, 1997,  Lindsay A. Rosenwald,
M.D. may be deemed  beneficially  to own (within the meaning of Rule 13d-3 under
the Securities  Exchange Act of 1934, as amended) 40.2% of the aggregate  voting
power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 372 45 M 20 7              13D                     Page 6 of 13 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Mr. Michael S. Weiss
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [x]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           PF (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          16,644
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 None
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   16,644 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          None
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           16,644
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.4% (less than 0.1% of the outstanding voting power)**
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           IN
- -------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the Issuer.  As of July 24, 1997, Mr. Michael S. Weiss
may be deemed  beneficially  to own  (within the meaning of Rule 13d-3 under the
Securities  Exchange Act of 1934,  as amended)  less than 0.1% of the  aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>


                                  SCHEDULE 13D


         This Amendment No. 1 amends and  supplements the following Items of the
Reporting  Persons'  Statement on Schedule 13D,  dated  February 24, 1997,  (the
"Schedule").

Item 2.  Identity and Background.

         The  information  contained in Item 2 to the Schedule is hereby amended
and supplemented to read in its entirety as follows:

     (a)  This  statement  is  filed  on  behalf  of  Paramount   Capital  Asset
          Management,  Inc.  ("Paramount  Capital"),  Aries Domestic Fund,  L.P.
          ("Aries  Domestic"),  The Aries Trust ("Aries Trust"),  Dr. Lindsay A.
          Rosenwald  (together with Paramount Capital,  Aries Domestic and Aries
          Trust,  the  "Aries  Reporting  Persons")  and Mr.  Michael  S.  Weiss
          (together with the Aries Reporting Persons, the "Filing Persons"). See
          attached  Exhibit M which is a copy of their  agreement  in writing to
          file this  statement  jointly on behalf of each of them. Mr. Weiss and
          the Aries  Reporting  Persons  have made,  and will  continue to make,
          their own investment decisions.  The investment decisions of Mr. Weiss
          may or may not coincide with the decisions made by the Aries Reporting
          Persons.  Each Filing Person expressly disclaims Mr. Weiss' membership
          in a "group" with the Aries  Reporting  Persons  within the meaning of
          Rule 13d-5(b)(1) of the Securities Exchange Act of 1934, as amended.

     (b)  The  business  address  of  Paramount  Capital,  Aries  Domestic,  Dr.
          Rosenwald and Mr. Weiss is 787 Seventh Avenue,  48th Floor,  New York,
          New  York,  10019.  The  business  address  for  Aries  Trust  is  c/o
          MeesPierson (Cayman) Limited,  P.O. Box 2003, British American Centre,
          Phase 3, Dr. Roy's Drive, George Town, Grand Cayman.

     (c)  Dr.  Rosenwald  is an  investment  banker,  venture  capitalist,  fund
          manager and sole shareholder of Paramount  Capital, 1/ a  Subchapter S
          corporation  incorporated in the State of Delaware.  Paramount Capital
          is the General  Partner of Aries  Domestic,  2/ a limited  partnership
          incorporated in Delaware. Paramount Capital is the Invest-

- --------

                  1/       Please  see  attached   Exhibit  B   indicating   the
                           executive officers and directors of Paramount Capital
                           and providing  information called for by Items 2-6 of
                           this  statement as to said  officers  and  directors.
                           Exhibit B is herein incorporated by reference.

                  2/       Please see attached  Exhibit C indicating the general
                           partner of Aries  Domestic and the general  partner's
                           executive   officers  and   directors  and  providing
                           information called for by Items 2-6 of this statement
                           as to said general partners,  officers and directors.
                           Exhibit C is herein incorporated by reference.


                               Page 7 of 13 Pages

<PAGE>

          ment Manager to Aries Trust, 3/ a Cayman Islands Trust. Mr. Weiss is a
          Senior  Managing  Director of  Paramount  Capital,  Inc. and also is a
          Director and Interim Chairman of the Issuer's Board of Directors.

     (d)  Dr. Rosenwald,  Mr. Weiss, Paramount Capital, Aries Domestic and Aries
          Trust and their  respective  officers,  directors,  general  partners,
          investment  managers,  and  trustees  have not,  during the five years
          prior to the date  hereof,  been  convicted  in a criminal  proceeding
          (excluding traffic violations or similar misdemeanors).

     (e)  Dr. Rosenwald,  Mr. Weiss, Paramount Capital, Aries Domestic and Aries
          Trust and their  respective  officers,  directors,  general  partners,
          investment managers, and trustees have not been, during the five years
          prior to the date hereof,  parties to a civil proceeding of a judicial
          or  administrative  body of competent  juris- diction,  as a result of
          which such  person was or is  subject to a  judgment,  decree or final
          order  enjoining  future  violations  of, or  prohibiting or mandating
          activities subject to, Federal or State securities laws or finding any
          violation with respect to such laws.

     (f)  Dr. Rosenwald and Mr. Weiss are citizens of the United States.


Item 3.  Source and Amount of Funds or Other Consideration.

         The  information  contained in Item 3 to the Schedule is hereby amended
by adding the following:

         On May 29, 1997,  Aries Trust and Aries  Domestic each delivered to the
Issuer an  Irrevocable  Notice of  Conversion  pursuant to which Aries Trust and
Aries Domestic  converted  $422,500 and $227,500  principal  amount of the Notes
into 8,450 and 4,550 shares of Series D Preferred Stock, respectively.  Pursuant
to an Amended and Restated Amendment Agreement (the "Amendment Agreement") filed
herewith as Exhibit Q, Aries Trust,  Aries Domestic and the Issuer,  inter alia,
(i) agreed to  postpone  the  maturity  date of the Notes to the  earlier of (x)
December 31, 1997 and (y) the date of any decision, order or other determination
adverse to the Issuer or any of its directors by any court or other  tribunal in
any lawsuit or other  proceeding  against the Issuer and/or any of its directors
by any of the Issuer's preferred  stockholders,  (ii) agreed that if Aries Trust
and Aries  Domestic  purchased  securities in the Private  Placement (as defined
below),  then Aries Trust and Aries  Domestic  would not vote or dispose of such
securities or convert any such securities  into, or exercise any such securities
for, any shares of Common Stock of the Issuer,  for a period of 90 days from the
date of such purchase,  (iii) changed the stated value of the Series D Preferred
Stock from ten dollars  ($10.00) per share to one hundred dollars  ($100.00) per
share, and the

- --------
                  3/       Please  see  attached   Exhibit  D   indicating   the
                           investment   manager  of  the  Aries  Trust  and  the
                           investment manager's executive officers and directors
                           and providing  information called for by Items 2-6 of
                           this  statement  as to said  investment  manager  and
                           officers   and   directors.   Exhibit   D  is  herein
                           incorporated by reference.


                               Page 8 of 13 Pages

<PAGE>

conversion rate of the Notes from five dollars ($5.00) to fifty dollars ($50.00)
per share,  in each case subject to  adjustment  upon the  occurrence of certain
events  and (iv)  exchanged  the  Class A and  Class B Bridge  Warrants  for New
Warrants in the forms filed herewith as Exhibits T, U, V and W.

         The  shares of Series D  Preferred  Stock  issued,  or  issuable,  upon
conversion of the Notes  (excluding  the interest on the Notes) are  convertible
into 6,357,616  shares of Common Stock of the Issuer at a conversion  rate equal
to $0.94375 per share,  subject to  adjustment  upon the  occurrence  of certain
events.  The New Warrants are  exerciseable for an aggregate of 6,357,616 shares
of  Common  Stock at an  exercise  price of  $0.471875  per  share,  subject  to
adjustment upon certain events.

         On June 30,  1997,  the  Issuer  concluded  a  private  placement  (the
"Private  Placement") of its securities for which Paramount Capital,  Inc. acted
as placement agent in  consideration  for certain cash success fees and warrants
(the "Placement  Warrants") to purchase up to 80,790 Class D Warrants and 16,158
shares of Series D Preferred  Stock, in each case subject to adjustment upon the
occurrence of certain events, for an aggregate of $1,777,380. Aries Domestic and
Aries Trust used  $304,500 and  $565,500 of their  respective  general  funds to
purchase  securities  of  the  Issuer  in  such  private  placement  consisting,
respectively,  of 3,500 and 6,500 shares of Series D Preferred  Stock and 17,500
and 32,500  Class D Warrants  which are  currently  convertible  for 370,861 and
688,742 and  exerciseable  for 17,500 and 32,500  shares of Common  Stock of the
Issuer,  respectively.  Mr. Weiss used $15,000 of his personal funds to purchase
securities of the Issuer in such private  placement  consisting of 150 shares of
Series  D  Preferred  Stock  and  750  Class  D  Warrants  which  are  currently
convertible  and  exerciseable  for 15,894 and 750 shares of Common Stock of the
Issuer,  respectively.  Paramount  Capital,  Inc. and the Issuer have entered an
agreement,  pursuant to which, in  consideration  of Paramount  Capital,  Inc.'s
services  as a financial  advisor,  Paramount  Capital,  Inc.'s  designees  will
receive,  inter alia,  warrants (the  "Advisory  Warrants") to purchase up to an
aggregate of 121,185  Class D Warrants  and 24,237  shares of Series D Preferred
Stock, in each case subject to adjustment upon the occurrence of certain events,
for an aggregate of  $2,666,070.  Both the  Placement  Warrants and the Advisory
Warrants are  exerciseable  between  December  31, 1997 and June 30,  2002.  The
Filing Persons disclaim beneficial  ownership of all the Common Stock except the
Purchased Common Stock. Mr. Weiss and the Aries Reporting  Persons each disclaim
beneficial ownership of all securities held by the other.


Item 4.  Purpose of Transaction.

         The  information  contained in Item 4 to the Schedule is hereby amended
by adding the following:

         The Filing Persons  acquired  securities of the Issuer as an investment
in the Issuer.  Except as indicated  in this  Schedule  13D, the Filing  Persons
currently  have no plans or  proposals  that relate to or would result in any of
the matters  described  in  subparagraphs  (a) through (j) of Item 4 of Schedule
13D.  Thomas H. Adams  resigned  from the Board of Directors  of the Issuer,  on
which he had  served  as  Chairman  of the  Board of  Directors,  and the  Aries
Reporting  Persons  appointed  Mr. Weiss as a Director and he was elected by the
Board as


                               Page 9 of 13 Pages

<PAGE>

Interim  Chairman  of the  Issuer's  Board of  Directors.  David R.  Walner,  an
Associate  Director of Paramount  Capital,  Inc.  and an Associate  Director and
Secretary of Paramount Capital,  has been appointed Secretary of the Issuer. The
Aries Reporting  Persons are considering the exercise of the rights set forth in
Section 7.20 of the Note and Warrant  Purchase  Agreement and are in the process
of identifying  potential  director  nominees.  The Reporting  Persons have also
discussed with  management of the Issuer the hiring of an individual to fill the
present vacancy in the position of Chief Executive Officer for the Issuer. Aries
Trust and Aries Domestic entered into a Line of Credit Agreement with the Issuer
pursuant to which Aries Trust and Aries Domestic provided the Issuer with a line
of credit of up to $500,000, which subsequently was repaid, in consideration for
warrants (the "Line of Credit Warrants") in the forms filed herewith as Exhibits
N and O, to purchase 50,000 shares of Common Stock of the Issuer exerciseable at
$2.50 per share, subject to adjustment upon the occurrence of certain events. On
April 25, 1997, the Court rejected the Plaintiffs' challenge to the Transactions
and ruled in favor of the Issuer, the Issuer's directors,  Aries Trust and Aries
Domestic,  who were the defendants.  The Court issued an opinion stating that it
will enter  judgment in favor of the Issuer and its  directors in the Suit.  The
Filing Persons may from time to time acquire, or dispose of, Common Stock and/or
other securities of the Issuer if and when they deem it appropriate.  The Filing
Persons may formulate other purposes, plans or proposals relating to any of such
securities  of the  Issuer to the  extent  deemed  advisable  in light of market
conditions, investment policies and other factors.


Item 5.  Interest in Securities of Issuer.

         The  information  contained in Item 5 to the Schedule is hereby amended
and supplemented to read in its entirety as follows:

     (a)  As of July 24, 1997, Dr. Rosenwald and Paramount Capital,  through the
          acquisitions of securities by Aries Trust and Aries  Domestic,  may be
          deemed  beneficially to own 14,333,054 shares or 76.6% of the Issuer's
          Common  Stock,  and Aries  Domestic,  Aries Trust and Mr. Weiss may be
          deemed  beneficially  to own the following  number of shares of Common
          Stock:


          Aries Domestic                     4,883,643
          Aries Trust                        9,082,692
          Mr. Weiss                             16,644

          Pursuant to Rule 13d-4 promulgated  under the Securities  Exchange Act
          of 1934, as amended,  the Filing Persons disclaim beneficial ownership
          of all the Common Stock except the Purchased Common Stock. Pursuant to
          Rule 13d-4 promulgated  under the Securities  Exchange Act of 1934, as
          amended,  the Aries  Reporting  Persons  and Mr.  Weiss each  disclaim
          beneficial ownership of all securities held by the other.

          The  outstanding  shares of Series D Preferred Stock of the Issuer are
          entitled  to vote  together  with the  holders of Common  Stock on all
          matters  submitted to a vote of stockholders of the Issuer. As of July
          24, 1997, the Aries  Reporting  Persons may be deemed  beneficially to
          own (within the  meaning of Rule 13d-3 under the  Securities  Exchange
          Act of 1934, as


                               Page 10 of 13 Pages

<PAGE>

          amended)  40.2% of the aggregate  voting power of the Common Stock and
          Series D Preferred Stock outstanding.

     (b)  Dr.  Rosenwald  and  Paramount  Capital  share the power to vote or to
          direct the vote,  to dispose  or to direct  the  disposition  of those
          shares owned by each of Aries Domestic and Aries Trust.  Mr. Weiss has
          the sole  power to direct  the vote and to  dispose  or to direct  the
          disposition of the shares that he owns.

     (c)  Other than the partial  conversion  of the Notes,  the exchange of the
          Class A Warrants and Class B Warrants for New Warrants, the receipt of
          the Line of Credit  Warrants  and the  purchase  of Series D Preferred
          Stock and Class D  Warrants  in the  private  placement  and the other
          transactions  described herein, the Reporting Persons have not engaged
          in any  transactions  in the Common Stock of the Issuer in the past 60
          days. See Item 3.

     (d & (e)       Not applicable.


Item 6.  Contracts, Arrangements, Understandings or Relationships With Respect
         to Securities of the Issuer.

         The  information  contained in Item 6 to the Schedule is hereby amended
and supplemented to read in its entirety as follows:

         Paramount  Capital is the  investment  manager  of Aries  Trust and the
General  Partner of Aries  Domestic and in such  capacities has the authority to
make  certain  investment  decisions  on  behalf  of  such  entities,  including
decisions  relating to the  securities  of the Issuer.  In  connection  with its
investment management duties, Paramount Capital receives certain management fees
and performance  allocations from Aries Trust and Aries Domestic.  Dr. Rosenwald
is the sole shareholder of Paramount Capital. Additionally, on January 28, 1997,
the Issuer entered into a Letter of Intent with Paramount Capital, Inc. pursuant
to which it was contemplated that Paramount Capital, Inc. would act as financial
advisor and investment banker for the Issuer in future capital raising and other
strategic  transactions for the Issuer. Dr. Rosenwald is the sole shareholder of
Paramount  Capital,  Inc.  On June 30,  1997,  the  Issuer  concluded  a private
placement of its securities for which Paramount Capital, Inc. acted as placement
agent in consideration for certain cash success fees and Placement Warrants (see
Item 3). In  addition,  Paramount  Capital,  Inc. and the Issuer have entered an
agreement,  pursuant to which, in  consideration  of Paramount  Capital,  Inc.'s
services  as a financial  advisor,  Paramount  Capital,  Inc.'s  designees  will
receive,  inter alia,  Advisory  Warrants  (see Item 3). On June 6, 1997,  Aries
Trust and Aries Domestic entered into a Line of Credit Agreement with the Issuer
pursuant to which Aries Trust and Aries Domestic advanced a line of credit of up
to  $500,000  in  consideration  of the Line of  Credit  Warrants  (see Item 4).
Certain directors and officers of Paramount Capital and Paramount Capital,  Inc.
are now also directors and/or officers of the Issuer (see Item 4).


                               Page 11 of 13 Pages

<PAGE>

         Except as indicated in this 13D and the  exhibits  hereto,  there is no
contract, arrangement,  understanding or relationship between the Filing Persons
and any other person, with respect to any securities of the Issuer.


Item 7.  Material to Be Filed as Exhibits

         The  information  contained in Item 7 to the Schedule is hereby amended
by adding the following Exhibits:

         Exhibit M:                 Agreement of Joint Filing of Schedule 13D.

         Exhibit N:                 Warrant for the purchase of 32,500 shares
                                    of  Common  Stock of the  Issuer,  issued to
                                    Aries Trust  pursuant to the Senior  Secured
                                    Line of Credit Agreement between the Issuer,
                                    Aries Trust and Aries Domestic.

         Exhibit O:                 Warrant for the purchase of 17,500 shares
                                    of  Common  Stock of the  Issuer,  issued to
                                    Aries   Domestic   pursuant  to  the  Senior
                                    Secured Line of Credit Agreement between the
                                    Issuer, Aries Trust and Aries Domestic.

         Exhibit P:                 Amended   Certificate  of  Designation   for
                                    Series  D  Convertible  Preferred  Stock  of
                                    Genta Incorporated.

         Exhibit Q:                 Amended  and  Restated  Amendment  Agreement
                                    between  the  Issuer,  Aries Trust and Aries
                                    Domestic.

         Exhibit R:                 Amended   and   Restated    Senior   Secured
                                    Convertible   Bridge  Note  for   $1,050,000
                                    issued to Aries Domestic.

         Exhibit S:                 Amended   and   Restated    Senior   Secured
                                    Convertible   Bridge  Note  for   $1,950,000
                                    issued to Aries Trust.

         Exhibit T:                 New Class A Bridge  Warrant for the Purchase
                                    of 350,000  shares of Common Stock issued to
                                    Aries Domestic.

         Exhibit U:                 New Class A Bridge  Warrant for the Purchase
                                    of 650,000  shares of Common Stock issued to
                                    Aries Trust.

         Exhibit V:                 New Class B Bridge  Warrant for the Purchase
                                    of 350,000  shares of Common Stock issued to
                                    Aries Domestic.

         Exhibit W:                 New Class B Bridge  Warrant for the Purchase
                                    of 650,000  shares of Common Stock issued to
                                    Aries Trust.


                               Page 12 of 13 Pages

<PAGE>

                                   SIGNATURES

         After  reasonable  inquiry and to the best  knowledge and belief of the
undersigned,  the  undersigned  certify that the  information  set forth in this
statement is true, complete and correct.

                    PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   July 24, 1997
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President

                                 ARIES DOMESTIC FUND, L.P.
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   July 24, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


                                 THE ARIES TRUST
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   July 24, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


Dated:   July 24, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.



Dated:   July 24, 1997
         New York, NY             By: /s/ Michael S. Weiss
                                     ---------------------------------------
                                    Mr. Michael S. Weiss


                               Page 13 of 13 Pages


<PAGE>

                                    EXHIBIT M

                                    AGREEMENT

                          JOINT FILING OF SCHEDULE 13D



                  The  undersigned  hereby agrees jointly to prepare and to file
with  regulatory  authorities a Schedule 13D and any future  amendments  thereto
reporting   each  of  the   undersigned's   ownership  of  securities  of  Genta
Incorporated  and hereby  affirm that such Schedule 13D is being filed on behalf
of each of the undersigned.

                                        PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   July 23, 1997
         New York, NY         By: /s/ Lindsay A. Rosenwald
                                  ---------------------------------
                                   Lindsay A. Rosenwald, M.D.
                                   President

                                ARIES DOMESTIC FUND, L.P.
                                By: Paramount Capital Asset Management, Inc.
                                    General Partner

Dated:   July 23, 1997
         New York, NY         By:  /s/ Lindsay A. Rosenwald
                                   --------------------------------
                                   Lindsay A. Rosenwald, M.D.
                                   President


                                THE ARIES TRUST
                              By: Paramount Capital Asset Management, Inc.
                                    Investment Manager

Dated:   July 23, 1997
         New York, NY         By:  /s/ Lindsay A. Rosenwald
                                   --------------------------------
                                   Lindsay A. Rosenwald, M.D.
                                   President


Dated:   July 23, 1997
         New York, NY          /s/ Lindsay A. Rosenwald
                               --------------------------------
                                   Lindsay A. Rosenwald, M.D.


Dated:   July 23, 1997
         New York, NY         /s/ Michael S. Weiss
                              ---------------------------------
                                   Mr. Michael S. Weiss




<PAGE>

                                   Exhibit N

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN OPINION OF COUNSEL  SATISFACTORY TO THE COMPANY THAT SUCH  REGISTRATION IS
NOT REQUIRED OR UNLESS SOLD  PURSUANT TO RULE 144 OF SUCH ACT. ANY SUCH TRANSFER
MAY ALSO BE SUBJECT TO APPLICABLE STATE SECURITIES LAWS.



                               GENTA INCORPORATED



                      WARRANT FOR THE PURCHASE OF SHARES OF
                      -------------------------------------
                                  COMMON STOCK
                                  ------------

NO. 1                                                              32,500 SHARES


                  FOR VALUE RECEIVED, GENTA INCORPORATED, a Delaware corporation
(the "Company"), hereby certifies that THE ARIES TRUST A CAYMAN ISLAND TRUST, or
its permitted assigns,  is entitled to purchase from the Company, at any time or
from time to time  commencing on June 6, 1997,  and prior to 5:00 P.M., New York
City  time,  on June  6,  2002  (the  "Termination  Date"),  thirty-two-thousand
five-hundred  (32,500) fully paid and non-assessable shares of the Common Stock,
$.001 par value per share, of the Company at an exercise price equal two dollars
and fifty cents ($2.50)  (Hereinafter,  (i) said Common Stock, together with any
other equity  securities which may be issued by the Company with respect thereto
or in  substitution  therefor,  is referred to as the "Common  Stock",  (ii) the
shares of the Common Stock purchasable  hereunder or under any other Warrant (as
hereinafter  defined)  are  referred  to as  the  "Warrant  Shares",  (iii)  the
aggregate purchase price payable for the Warrant Shares hereunder is referred to
as the "Aggregate Warrant Price", (iv) the price payable for each of the Warrant
Shares  hereunder  is referred  to as the "Per Share  Warrant  Price",  (v) this
Warrant,  all  similar  Warrants  issued  on the date  hereof  and all  warrants
hereafter  issued in exchange or  substitution  for this Warrant or such similar
Warrants are referred to as the  "Warrants"  and (vi) the holder of this Warrant
is  referred  to as the  "Holder"  and the holder of this  Warrant and all other
Warrants or Warrant  Shares issued upon the exercise of any Warrant are referred
to as the "Holders").  The Aggregate Warrant Price is not subject to adjustment.
The Per Share Warrant Price is subject to adjustment as hereinafter provided; in
the event of any such adjustment, the number of Warrant Shares shall be adjusted
by dividing the Aggregate Warrant Price by the Per Share Warrant Price in effect
immediately after such adjustment.


<PAGE>

                  1.       Exercise of Warrant.

                  (a) This Warrant may be exercised,  in whole at any time or in
part from time to time,  commencing on June 6, 1997 and prior to the Termination
Date, by the holder:

              (i) by the surrender of this Warrant (with the  subscription  form
              at the end  hereof  duly  executed)  at the  address  set forth in
              Subsection  9(a)  hereof,  together  with  proper  payment  of the
              Aggregate Warrant Price, or the proportionate part thereof if this
              Warrant is exercised in part, with payment for Warrant Shares made
              by  certified or official  bank check  payable to the order of the
              Company; or

              (ii) by the surrender of this Warrant (with the cashless  exercise
              form at the end hereof duly  executed) (a "Cashless  Exercise") at
              the address set forth in Subsection 9(a) hereof. Such presentation
              and surrender shall be deemed a waiver of the Holder's  obligation
              to pay the Aggregate  Warrant  Price,  or the  proportionate  part
              thereof if this Warrant is  exercised  in part.  In the event of a
              Cashless Exercise,  the Holder shall exchange its Warrant for that
              number  of  Warrant  Shares  subject  to  such  Cashless  Exercise
              multiplied  by a  fraction,  the  numerator  of which shall be the
              difference  between the then  current  Market  Price per share (as
              hereinafter  defined)  of Common  Stock and the Per Share  Warrant
              Price,  and the  denominator  of which  shall be the then  current
              Market Price per share of Common  Stock.  The then current  market
              price  per  share of the  Common  Stock at any date  (the  "Market
              Price")  shall be deemed to be the last sale  price of the  Common
              Stock  on the  business  day  prior  to the  date of the  Cashless
              Exercise  or, in case no such  reported  sales  take place on such
              day, the average of the last  reported bid and asked prices of the
              Common Stock on such day, in either case on the principal national
              securities  exchange  on which the  Common  Stock is  admitted  to
              trading or listed,  or if not listed or admitted to trading on any
              such exchange,  the representative closing bid price of the Common
              Stock as  reported by the NASDAQ  Bulletin  Board  ("NASDAQ"),  or
              other similar  organization if NASDAQ is no longer  reporting such
              information,  or if not so available, the fair market price of the
              Common  Stock  as  determined  in  good  faith  by  the  Board  of
              Directors.

                  (b) If this Warrant is exercised in part, this Warrant must be
exercised  for a number of whole  shares of the  Common  Stock and the Holder is
entitled to receive a new Warrant  covering  the Warrant  Shares  which have not
been exercised and setting forth the proportionate part of the Aggregate Warrant
Price  applicable to such Warrant  Shares.  Upon surrender of this Warrant,  the
Company will (i) issue a certificate or  certificates  in the name of the Holder
for the largest  number of whole  shares of the Common Stock to which the Holder
shall be entitled  and, if this Warrant is  exercised  in whole,  in lieu of any
fractional share of the Common Stock to which the Holder shall be entitled,  pay
to the Holder cash in an amount equal to the fair value of such fractional share
(determined in such reasonable manner as the Board of Directors of the Company


                                      - 2 -

<PAGE>

shall  determine),   and  (ii)  deliver  the  other  securities  and  properties
receivable upon the exercise of this Warrant,  if any, or the proportionate part
thereof if this Warrant is exercised in part, pursuant to the provisions of this
Warrant.

                  2. Reservation of Warrant Shares;  Listing. The Company agrees
that, prior to the expiration of this Warrant, the Company will at all times (a)
have authorized and in reserve, and will keep available,  solely for issuance or
delivery upon the exercise of this  Warrant,  the shares of the Common Stock and
other  securities and  properties as from time to time shall be receivable  upon
the  exercise of this  Warrant,  free and clear of all  restrictions  on sale or
transfer,  except  for the  restrictions  on sale or  transfer  set forth in the
Securities Act of 1933, as amended (the "Act"),  and restrictions  created by or
on behalf of the Holder,  and free and clear of all preemptive rights and rights
of first  refusal;  and (b) when the Company  prepares and files a  registration
statement  covering the shares of Common Stock issued or issuable  upon exercise
of this Warrant with the  Securities and Exchange  Commission  (the "SEC") which
registration  statement  is declared  effective by the SEC under the Act and the
Company  lists its Common  Stock on any  national  securities  exchange or other
quotation system, it will use its reasonable best efforts to cause the shares of
Common Stock  subject to this Warrant to be listed on such exchange or quotation
system.

                  3. Protection Against Dilution.

                  (a) If,  at any time or from  time to time  after  the date of
this Warrant,  the Company shall issue or distribute to the holders of shares of
Common Stock evidence of its  indebtedness,  any other securities of the Company
or any cash,  property or other assets (excluding a subdivision,  combination or
reclassification, or dividend or distribution payable in shares of Common Stock,
referred to in  Subsection  3(b),  and also  excluding  cash  dividends  or cash
distributions  paid out of net profits  legally  available  therefor in the full
amount   thereof,   which  together  with  the  value  of  other  dividends  and
distributions  made substantially  concurrently  therewith or pursuant to a plan
which includes payment thereof, is equivalent to not more than five percent (5%)
of the Company's net worth) (any such  non-excluded  event being herein called a
"Special  Dividend"),   the  Per  Share  Warrant  Price  shall  be  adjusted  by
multiplying  the Per Share  Warrant  Price  then in effect  by a  fraction,  the
numerator  of which shall be the then  current  Market Price of the Common Stock
less the fair market value (as  determined in good faith by the Company's  Board
of Directors) of the evidence of indebtedness,  cash, securities or property, or
other assets issued or  distributed in such Special  Dividend  applicable to one
share of Common  Stock and the  denominator  of which shall be the then  current
Market Price of the Common Stock. An adjustment made pursuant to this Subsection
3(a)  shall  become  effective  immediately  after the  record  date of any such
Special Dividend.

                  (b) In case the Company shall  hereafter (i) pay a dividend or
make a  distribution  on its  capital  stock in  shares of  Common  Stock,  (ii)
subdivide  its  outstanding  shares of  Common  Stock  into a greater  number of
shares,  (iii)  combine its  outstanding  shares of Common  Stock into a smaller
number of shares  or (iv)  issue by  reclassification  of its  Common  Stock any
shares of capital stock of the Company, the Per Share Warrant


                                      - 3 -

<PAGE>

Price shall be adjusted to be equal to a fraction,  the numerator of which shall
be the Aggregate  Warrant Price and the denominator of which shall be the number
of shares of Common Stock or other  capital  stock of the Company which he would
have owned  immediately  following  such action had such Warrant been  exercised
immediately  prior thereto.  An adjustment made pursuant to this Subsection 3(b)
shall  become  effective  immediately  after  the  record  date in the case of a
dividend  or  distribution  and shall  become  effective  immediately  after the
effective date in the case of a subdivision, combination or reclassification.

                  (c) Except as provided in  Subsections  3(a) and 3(d), in case
the Company  shall  hereafter  issue or sell any Common  Stock,  any  securities
convertible  into Common  Stock or any  rights,  options or warrants to purchase
Common Stock or securities  convertible  into Common  Stock,  in each case for a
price per share or entitling the holders  thereof to purchase  Common Stock at a
price per share  (determined by dividing (i) the total amount,  if any, received
or  receivable by the Company in  consideration  of the issuance or sale of such
securities  plus the total  consideration,  if any,  payable to the Company upon
exercise or conversion thereof (the "Total Consideration") by (ii) the number of
additional  shares of Common Stock  issuable upon exercise or conversion of such
securities)  less than either the then current  Market Price of the Common Stock
or the current Per Share Warrant Price in effect on the date of such issuance or
sale, the Per Share Warrant Price shall be adjusted by multiplying the Per Share
Warrant Price then in effect by a fraction,  the numerator of which shall be (x)
the sum of (A) the number of shares of Common Stock  outstanding  on the date of
such  issuance  or sale plus (B) the Total  Consideration  divided by either the
current Market Price of the Common Stock or the current Per Share Warrant Price,
whichever is greater,  and the  denominator  of which shall be (y) the number of
shares of Common Stock outstanding on the date of such issuance or sale plus the
maximum  number of additional  shares of Common Stock  issued,  sold or issuable
upon exercise or conversion of such securities.

                  (d) No  adjustment  in the Per Share  Warrant  Price  shall be
required in the case of the issuance by the Company of (i) Common Stock pursuant
to the exercise or conversion of any Warrant or any other  options,  warrants or
any convertible  securities currently  outstanding or outstanding as a result of
securities  issued in connection with the Company's  current  private  placement
offering  pursuant  to the  Confidential  Term  Sheet  dated  May 20,  1997  (as
hereafter  supplemented  and amended,  the "Term  Sheet")  pursuant to a private
placement  of the  Company's  securities  (an  "Offering");  provided,  that the
exercise  price  or  conversion  price  at  which  such  options,   warrants  or
convertible securities are exercised or converted,  as the case may be, is equal
to the  exercise  price or  conversion  price in  effect  as of the date of this
Warrant or as of the date of issuance with respect to securities issued pursuant
to an Offering (except for standard  anti-dilution  adjustments) and (ii) shares
of Common Stock issued or sold pursuant to stock  purchase or stock option plans
or other  similar  arrangements  that are  approved  by the  Company's  Board of
Directors.

                  (e) In case of any capital reorganization or reclassification,
or any  consolidation  or merger to which the  Company  is a party  other than a
merger or consolidation in which the Company is the continuing  corporation,  or
in case of any sale


                                      - 4 -

<PAGE>

or conveyance to another entity of the property of the Company as an entirety or
substantially  as an  entirety,  or in the  case of any  statutory  exchange  of
securities  with  another  corporation   (including  any  exchange  effected  in
connection with a merger of a third corporation into the Company), the Holder of
this Warrant shall have the right  thereafter to receive on the exercise of this
Warrant  the kind and amount of  securities,  cash or other  property  which the
Holder would have owned or have been entitled to receive  immediately after such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or  conveyance  had this Warrant been  exercised  immediately  prior to the
effective date of such reorganization, reclassification,  consolidation, merger,
statutory  exchange,  sale or  conveyance  and in any such case,  if  necessary,
appropriate  adjustment  shall be made in the  application of the provisions set
forth in this Section 3 with respect to the rights and  interests  thereafter of
the  Holder of this  Warrant  to the end that the  provisions  set forth in this
Section 3 shall thereafter  correspondingly be made applicable, as nearly as may
reasonably  be,  in  relation  to any  shares  of stock or other  securities  or
property  thereafter  deliverable  on the  exercise of this  Warrant.  The above
provisions  of  this   Subsection  3(e)  shall  similarly  apply  to  successive
reorganizations,    reclassifications,    consolidations,   mergers,   statutory
exchanges,  sales or  conveyances.  The  issuer of any  shares of stock or other
securities or property  thereafter  deliverable  on the exercise of this Warrant
shall be responsible  for all of the  agreements and  obligations of the Company
hereunder. Notice of any such reorganization,  reclassification,  consolidation,
merger,  statutory  exchange,  sale  or  conveyance  and of said  provisions  so
proposed  to be made,  shall be mailed to the Holders of the  Warrants  not less
than thirty (30) days prior to such event. A sale of all or substantially all of
the assets of the Company for a consideration consisting primarily of securities
shall be deemed a consolidation or merger for the foregoing purposes.

                  (f) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (g) No  adjustment  in the Per Share  Warrant  Price  shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.05 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  Subsection  3(g) are not  required  to be made shall be
carried forward and taken into account in any subsequent  adjustment;  provided,
further, however, that adjustments shall be required and made in accordance with
the  provisions  of this Section 3 (other than this  Subsection  3(g)) not later
than such time as may be required in order to preserve the tax-free  nature of a
distribution to the Holder of this Warrant or Common Stock issuable upon


                                      - 5 -

<PAGE>

the exercise hereof.  All calculations under this Section 3 shall be made to the
nearest cent or to the nearest  1/100th of a share, as the case may be. Anything
in this Section 3 to the contrary notwithstanding, the Company shall be entitled
to make such  reductions  in the Per Share Warrant  Price,  in addition to those
required by this Section 3, as it in its  discretion  shall deem to be advisable
in order  that any stock  dividend,  subdivision  of shares or  distribution  of
rights to purchase  stock or securities  convertible or  exchangeable  for stock
hereafter made by the Company to its stockholders shall not be taxable.

                  (h)  Whenever  the Per  Share  Warrant  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants in accordance  with this Section 3, the Chief  Financial  Officer of
the Company shall  promptly  prepare a  certificate  setting forth the Per Share
Warrant  Price and the number of Warrant  Shares  after such  adjustment  or the
effect of such  modification  and a brief  statement of the facts requiring such
adjustment or modification and the manner of computing the same and cause copies
of such certificate to be mailed to the Holders of the Warrants. In the event of
a dispute with  respect to any  adjustment  required  pursuant to Section 3, the
Holder may appoint, at the Company's expense,  an independent  financial advisor
(e.g. an  investment  banking or  accounting  firm)reasonably  acceptable to the
Company to calculate such adjustment.  Such determination  shall be binding upon
the Holder and the Company.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 15 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the  allocation of the adjusted Per Share Warrant Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  4. Fully Paid Stock; Taxes. The Company agrees that the shares
of the Common Stock  represented by each and every certificate of Warrant Shares
delivered  on the exercise of this  Warrant be validly  issued and  outstanding,
fully paid and nonassessable,  and not subject to preemptive rights or rights of
first refusal, and the Company will take all such actions as may be necessary to
assure that the par value or stated value, if any, per share of the Common Stock
is at all  times  equal to or less than the then Per Share  Warrant  Price.  The
Company further covenants and agrees that it will pay, when due and payable, any
and all Federal and state stamp,  original  issue or similar  taxes which may be
payable in respect of the issue of any Warrant Share or any certificate thereof.

                  5. Registration Under Securities Act of 1933.


                                      - 6 -

<PAGE>

                  (a) The Company shall include the Warrant  Shares on the Shelf
Registration  Statement  (as  defined in the Term  Sheet)  and the Holder  shall
otherwise  have  the  registration   rights  set  forth  in  Section  5  of  the
subscription agreement (the "Subscription Agreement") to be entered into between
the  purchasers  of units (as  described in the Term Sheet) and the Company.  By
acceptance  of this  Warrant,  the  Holder  agrees  that it shall  have the same
obligations,  and otherwise comply with, the provisions in such Section 5 of the
Subscription  Agreement  to same  extent as if it were a party  thereto.  To the
extent that no Final  Closing  Date (as defined in the  Subscription  Agreement)
occurs or the Offering is terminated,  the rights granted to Holder hereunder to
have its shares  registered shall begin as of December 6, 1997 on the same terms
as provided in Section 5 of the Subscription Agreement.

                  (b)  Until  all   Warrant   Shares  have  been  sold  under  a
Registration  Statement  or  pursuant  to Rule 144,  the  Company  shall use its
reasonable best efforts to file with the Securities and Exchange  Commission all
current  reports and the information as may be necessary to enable the Holder to
effect sales of its shares in reliance upon Rule 144 promulgated under the Act.

                  6.  Limited  Transferability.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws.
The Company may treat the registered  Holder of this Warrant as he or it appears
on the Company's  books at any time as the Holder for all purposes.  The Company
shall  permit  any  Holder of a Warrant or his duly  authorized  attorney,  upon
written  request during  ordinary  business  hours,  to inspect and copy or make
extracts from its books showing the registered holders of Warrants. All warrants
issued upon the  transfer or  assignment  of this Warrant will be dated the same
date as this Warrant, and all rights of the holder thereof shall be identical to
those of the Holder.

                  7.  Loss,   etc.,   of  Warrant.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  8.  Warrant  Holder  Not  Shareholder.   Except  as  otherwise
provided herein,  this Warrant does not confer upon the Holder any right to vote
or to consent to or receive notice as a stockholder of the Company,  as such, in
respect of any  matters  whatsoever,  or any other  rights or  liabilities  as a
stockholder, prior to the exercise hereof.

                  9. Communication.  No notice or other communication under this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:

                  (a) the Company at 3550 General  Atomics Court,  San Diego, CA
92121:


                                      - 7 -

<PAGE>

President  or other  address as the  Company  has  designated  in writing to the
Holder, or

                  (b) the  Holder at c/o  Paramount  Capital  Asset  Management,
Inc., 787 Seventh Avenue, New York, NY, 10019, Attn: Lindsay A. Rosenwald,  M.D.
or other such address as the Holder has designated in writing to the Company.

                  10. Headings.  The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.

                  11.  Applicable  Law.  This  Warrant  shall be governed by and
construed in  accordance  with the law of the State of New York  without  giving
effect to the principles of conflicts of law thereof.


                                      - 8 -

<PAGE>

         IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by
its President and its corporate seal to be hereunto  affixed and attested by its
Secretary this 6th day of June 1997.


                                        GENTA INCORPORATED



                                        By: ______________________________
                                        Name:
                                        Title:

ATTEST:



- -------------------------------
         Secretary

[Corporate Seal]


<PAGE>

                                  SUBSCRIPTION
                                  -------------


                  The   undersigned,   ___________________,   pursuant   to  the
provisions of the foregoing Warrant, hereby agrees to subscribe for and purchase
____________________  shares of the Common Stock,  par value $.001 per share, of
Genta Incorporated  covered by said Warrant,  and makes payment therefor in full
at the price per share provided by said Warrant.

Dated:_______________                      Signature:____________________

                                           Address:______________________



                                CASHLESS EXERCISE
                                -----------------

                  The   undersigned   ___________________,   pursuant   to   the
provisions of the foregoing  Warrant,  hereby elects to exchange its Warrant for
___________________  shares of Common Stock, par value $.001 per share, of Genta
Incorporated pursuant to the Cashless Exercise provisions of the Warrant.

Dated:_______________                      Signature:____________________

                                           Address:______________________



                                   ASSIGNMENT
                                   ----------

                  FOR VALUE RECEIVED  _______________  hereby sells, assigns and
transfers  unto  ____________________  the  foregoing  Warrant  and  all  rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
_____________________,  attorney, to transfer said Warrant on the books of Genta
Incorporated.

Dated:_______________                      Signature:____________________

                                           ADDRESS:______________________


<PAGE>

                               PARTIAL ASSIGNMENT
                               ------------------

                  FOR  VALUE   RECEIVED   _______________   hereby  assigns  and
transfers unto  ____________________ the right to purchase _______ shares of the
Common Stock,  par value $.001 per share, of Genta  Incorporated  covered by the
foregoing  Warrant,  and a  proportionate  part of said  Warrant  and the rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
____________________,  attorney,  to transfer  that part of said  Warrant on the
books of Genta Incorporated.

Dated:_______________                      Signature:____________________

                                           ADDRESS:______________________


<PAGE>

                                   Exhibit O

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN OPINION OF COUNSEL  SATISFACTORY TO THE COMPANY THAT SUCH  REGISTRATION IS
NOT REQUIRED OR UNLESS SOLD  PURSUANT TO RULE 144 OF SUCH ACT. ANY SUCH TRANSFER
MAY ALSO BE SUBJECT TO APPLICABLE STATE SECURITIES LAWS.



                               GENTA INCORPORATED



                      WARRANT FOR THE PURCHASE OF SHARES OF
                      -------------------------------------
                                  COMMON STOCK
                                  ------------

NO. 1                                                              17,500 SHARES


                  FOR VALUE RECEIVED, GENTA INCORPORATED, a Delaware corporation
(the  "Company"),  hereby  certifies  that ARIES  DOMESTIC  FUND,  L.P.,  or its
permitted assigns, is entitled to purchase from the Company, at any time or from
time to time  commencing on June 6, 1997,  and prior to 5:00 P.M., New York City
time, on June 6, 2002 (the "Termination Date"),  seventeen-thousand five-hundred
(17,500)  fully paid and  non-assessable  shares of the Common Stock,  $.001 par
value per share,  of the  Company at an exercise  price equal two dollars  fifty
cents  ($2.50)  (Hereinafter,  (i) said Common  Stock,  together  with any other
equity  securities which may be issued by the Company with respect thereto or in
substitution  therefor, is referred to as the "Common Stock", (ii) the shares of
the  Common  Stock  purchasable   hereunder  or  under  any  other  Warrant  (as
hereinafter  defined)  are  referred  to as  the  "Warrant  Shares",  (iii)  the
aggregate purchase price payable for the Warrant Shares hereunder is referred to
as the "Aggregate Warrant Price", (iv) the price payable for each of the Warrant
Shares  hereunder  is referred  to as the "Per Share  Warrant  Price",  (v) this
Warrant,  all  similar  Warrants  issued  on the date  hereof  and all  warrants
hereafter  issued in exchange or  substitution  for this Warrant or such similar
Warrants are referred to as the  "Warrants"  and (vi) the holder of this Warrant
is  referred  to as the  "Holder"  and the holder of this  Warrant and all other
Warrants or Warrant  Shares issued upon the exercise of any Warrant are referred
to as the "Holders").  The Aggregate Warrant Price is not subject to adjustment.
The Per Share Warrant Price is subject to adjustment as hereinafter provided; in
the event of any such adjustment, the number of Warrant Shares shall be adjusted
by dividing the Aggregate Warrant Price by the Per Share Warrant Price in effect
immediately after such adjustment.


<PAGE>

                  1.       Exercise of Warrant.

                  (a) This Warrant may be exercised,  in whole at any time or in
part from time to time,  commencing on June 6, 1997 and prior to the Termination
Date, by the holder:

             (i) by the surrender of this Warrant (with the  subscription  form
              at the end  hereof  duly  executed)  at the  address  set forth in
              Subsection  9(a)  hereof,  together  with  proper  payment  of the
              Aggregate Warrant Price, or the proportionate part thereof if this
              Warrant is exercised in part, with payment for Warrant Shares made
              by  certified or official  bank check  payable to the order of the
              Company; or

              (ii) by the surrender of this Warrant (with the cashless  exercise
              form at the end hereof duly  executed) (a "Cashless  Exercise") at
              the address set forth in Subsection 9(a) hereof. Such presentation
              and surrender shall be deemed a waiver of the Holder's  obligation
              to pay the Aggregate  Warrant  Price,  or the  proportionate  part
              thereof if this Warrant is  exercised  in part.  In the event of a
              Cashless Exercise,  the Holder shall exchange its Warrant for that
              number  of  Warrant  Shares  subject  to  such  Cashless  Exercise
              multiplied  by a  fraction,  the  numerator  of which shall be the
              difference  between the then  current  Market  Price per share (as
              hereinafter  defined)  of Common  Stock and the Per Share  Warrant
              Price,  and the  denominator  of which  shall be the then  current
              Market Price per share of Common  Stock.  The then current  market
              price  per  share of the  Common  Stock at any date  (the  "Market
              Price")  shall be deemed to be the last sale  price of the  Common
              Stock  on the  business  day  prior  to the  date of the  Cashless
              Exercise  or, in case no such  reported  sales  take place on such
              day, the average of the last  reported bid and asked prices of the
              Common Stock on such day, in either case on the principal national
              securities  exchange  on which the  Common  Stock is  admitted  to
              trading or listed,  or if not listed or admitted to trading on any
              such exchange,  the representative closing bid price of the Common
              Stock as  reported by the NASDAQ  Bulletin  Board  ("NASDAQ"),  or
              other similar  organization if NASDAQ is no longer  reporting such
              information,  or if not so available, the fair market price of the
              Common  Stock  as  determined  in  good  faith  by  the  Board  of
              Directors.

                  (b) If this Warrant is exercised in part, this Warrant must be
exercised  for a number of whole  shares of the  Common  Stock and the Holder is
entitled to receive a new Warrant  covering  the Warrant  Shares  which have not
been exercised and setting forth the proportionate part of the Aggregate Warrant
Price  applicable to such Warrant  Shares.  Upon surrender of this Warrant,  the
Company will (i) issue a certificate or  certificates  in the name of the Holder
for the largest  number of whole  shares of the Common Stock to which the Holder
shall be entitled  and, if this Warrant is  exercised  in whole,  in lieu of any
fractional share of the Common Stock to which the Holder shall be entitled,  pay
to the Holder cash in an amount equal to the fair value of such fractional share
(determined in such  reasonable  manner as the Board of Directors of the Company
shall  determine),   and  (ii)  deliver  the  other  securities  and  properties
receivable upon the exercise of this Warrant,  if any, or the proportionate part
thereof if this Warrant is exercised in part, pursuant to the provisions of


                                      - 2 -

<PAGE>

this Warrant.

                  2. Reservation of Warrant Shares;  Listing. The Company agrees
that, prior to the expiration of this Warrant, the Company will at all times (a)
have authorized and in reserve, and will keep available,  solely for issuance or
delivery upon the exercise of this  Warrant,  the shares of the Common Stock and
other  securities and  properties as from time to time shall be receivable  upon
the  exercise of this  Warrant,  free and clear of all  restrictions  on sale or
transfer,  except  for the  restrictions  on sale or  transfer  set forth in the
Securities Act of 1933, as amended (the "Act"),  and restrictions  created by or
on behalf of the Holder,  and free and clear of all preemptive rights and rights
of first  refusal;  and (b) when the Company  prepares and files a  registration
statement  covering the shares of Common Stock issued or issuable  upon exercise
of this Warrant with the  Securities and Exchange  Commission  (the "SEC") which
registration  statement  is declared  effective by the SEC under the Act and the
Company  lists its Common  Stock on any  national  securities  exchange or other
quotation system, it will use its reasonable best efforts to cause the shares of
Common Stock  subject to this Warrant to be listed on such exchange or quotation
system.

                  3. Protection Against Dilution.

                  (a) If,  at any time or from  time to time  after  the date of
this Warrant,  the Company shall issue or distribute to the holders of shares of
Common Stock evidence of its  indebtedness,  any other securities of the Company
or any cash,  property or other assets (excluding a subdivision,  combination or
reclassification, or dividend or distribution payable in shares of Common Stock,
referred to in  Subsection  3(b),  and also  excluding  cash  dividends  or cash
distributions  paid out of net profits  legally  available  therefor in the full
amount   thereof,   which  together  with  the  value  of  other  dividends  and
distributions  made substantially  concurrently  therewith or pursuant to a plan
which includes payment thereof, is equivalent to not more than five percent (5%)
of the  Company's net worth) (any such  nonexcluded  event being herein called a
"Special  Dividend"),   the  Per  Share  Warrant  Price  shall  be  adjusted  by
multiplying  the Per Share  Warrant  Price  then in effect  by a  fraction,  the
numerator  of which shall be the then  current  Market Price of the Common Stock
less the fair market value (as  determined in good faith by the Company's  Board
of Directors) of the evidence of indebtedness,  cash, securities or property, or
other assets issued or  distributed in such Special  Dividend  applicable to one
share of Common  Stock and the  denominator  of which shall be the then  current
Market Price of the Common Stock. An adjustment made pursuant to this Subsection
3(a)  shall  become  effective  immediately  after the  record  date of any such
Special Dividend.

                  (b) In case the Company shall  hereafter (i) pay a dividend or
make a  distribution  on its  capital  stock in  shares of  Common  Stock,  (ii)
subdivide  its  outstanding  shares of  Common  Stock  into a greater  number of
shares,  (iii)  combine its  outstanding  shares of Common  Stock into a smaller
number of shares  or (iv)  issue by  reclassification  of its  Common  Stock any
shares of capital  stock of the Company,  the Per Share  Warrant  Price shall be
adjusted  to be  equal  to a  fraction,  the  numerator  of  which  shall be the
Aggregate  Warrant  Price and the  denominator  of which  shall be the number of
shares of Common Stock or other capital stock of the Company which he would have
owned immediately following


                                      - 3 -

<PAGE>

such action had such  Warrant  been  exercised  immediately  prior  thereto.  An
adjustment  made  pursuant  to  this  Subsection  3(b)  shall  become  effective
immediately  after the record date in the case of a dividend or distribution and
shall become  effective  immediately  after the effective  date in the case of a
subdivision, combination or reclassification.

                  (c) Except as provided in  Subsections  3(a) and 3(d), in case
the Company  shall  hereafter  issue or sell any Common  Stock,  any  securities
convertible  into Common  Stock or any  rights,  options or warrants to purchase
Common Stock or securities  convertible  into Common  Stock,  in each case for a
price per share or entitling the holders  thereof to purchase  Common Stock at a
price per share  (determined by dividing (i) the total amount,  if any, received
or  receivable by the Company in  consideration  of the issuance or sale of such
securities  plus the total  consideration,  if any,  payable to the Company upon
exercise or conversion thereof (the "Total Consideration") by (ii) the number of
additional  shares of Common Stock  issuable upon exercise or conversion of such
securities)  less than either the then current  Market Price of the Common Stock
or the current Per Share Warrant Price in effect on the date of such issuance or
sale, the Per Share Warrant Price shall be adjusted by multiplying the Per Share
Warrant Price then in effect by a fraction,  the numerator of which shall be (x)
the sum of (A) the number of shares of Common Stock  outstanding  on the date of
such  issuance  or sale plus (B) the Total  Consideration  divided by either the
current Market Price of the Common Stock or the current Per Share Warrant Price,
whichever is greater,  and the  denominator  of which shall be (y) the number of
shares of Common Stock outstanding on the date of such issuance or sale plus the
maximum  number of additional  shares of Common Stock  issued,  sold or issuable
upon exercise or conversion of such securities.

                  (d) No  adjustment  in the Per Share  Warrant  Price  shall be
required in the case of the issuance by the Company of (i) Common Stock pursuant
to the exercise or conversion of any Warrant or any other  options,  warrants or
any convertible  securities currently  outstanding or outstanding as a result of
securities  issued in connection with the Company's  current  private  placement
offering  pursuant  to the  Confidential  Term  Sheet  dated  May 20,  1997  (as
hereafter  supplemented  and amended,  the "Term  Sheet")  pursuant to a private
placement  of the  Company's  securities  (an  "Offering");  provided,  that the
exercise  price  or  conversion  price  at  which  such  options,   warrants  or
convertible securities are exercised or converted,  as the case may be, is equal
to the  exercise  price or  conversion  price in  effect  as of the date of this
Warrant or as of the date of issuance with respect to securities issued pursuant
to an Offering (except for standard  anti-dilution  adjustments) and (ii) shares
of Common Stock issued or sold pursuant to stock  purchase or stock option plans
or other  similar  arrangements  that are  approved  by the  Company's  Board of
Directors.

                  (e) In case of any capital reorganization or reclassification,
or any  consolidation  or merger to which the  Company  is a party  other than a
merger or consolidation in which the Company is the continuing  corporation,  or
in case of any sale or  conveyance  to  another  entity of the  property  of the
Company as an entirety or  substantially  as an entirety,  or in the case of any
statutory  exchange  of  securities  with  another  corporation  (including  any
exchange  effected in connection with a merger of a third  corporation  into the
Company),  the Holder of this Warrant shall have the right thereafter to receive
on the


                                     - 4 -

<PAGE>

exercise  of this  Warrant  the kind and  amount  of  securities,  cash or other
property  which the Holder  would have  owned or have been  entitled  to receive
immediately after such reorganization, reclassification,  consolidation, merger,
statutory  exchange,   sale  or  conveyance  had  this  Warrant  been  exercised
immediately   prior   to   the   effective   date   of   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
and in any such case, if necessary,  appropriate adjustment shall be made in the
application  of the  provisions  set forth in this Section 3 with respect to the
rights and  interests  thereafter  of the Holder of this Warrant to the end that
the provisions set forth in this Section 3 shall thereafter  correspondingly  be
made  applicable,  as nearly as may  reasonably be, in relation to any shares of
stock or other securities or property thereafter  deliverable on the exercise of
this Warrant. The above provisions of this Subsection 3(e) shall similarly apply
to  successive  reorganizations,  reclassifications,   consolidations,  mergers,
statutory exchanges, sales or conveyances.  The issuer of any shares of stock or
other  securities  or property  thereafter  deliverable  on the exercise of this
Warrant shall be responsible  for all of the  agreements and  obligations of the
Company  hereunder.   Notice  of  any  such  reorganization,   reclassification,
consolidation,  merger,  statutory  exchange,  sale  or  conveyance  and of said
provisions  so  proposed  to be made,  shall be  mailed  to the  Holders  of the
Warrants  not less than thirty  (30) days prior to such event.  A sale of all or
substantially  all of the assets of the Company for a  consideration  consisting
primarily  of  securities  shall be deemed a  consolidation  or  merger  for the
foregoing purposes.

                  (f) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (g) No  adjustment  in the Per Share  Warrant  Price  shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.05 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  Subsection  3(g) are not  required  to be made shall be
carried forward and taken into account in any subsequent  adjustment;  provided,
further, however, that adjustments shall be required and made in accordance with
the  provisions  of this Section 3 (other than this  Subsection  3(g)) not later
than such time as may be required in order to preserve the tax-free  nature of a
distribution  to the Holder of this  Warrant or Common Stock  issuable  upon the
exercise  hereof.  All  calculations  under this  Section 3 shall be made to the
nearest cent or to the nearest  1/100th of a share, as the case may be. Anything
in this Section 3 to the contrary notwithstanding, the Company shall be entitled
to make such  reductions  in the Per Share Warrant  Price,  in addition to those
required by this Section 3, as it in its discretion shall


                                      - 5 -

<PAGE>

deem to be advisable in order that any stock dividend,  subdivision of shares or
distribution   of  rights  to  purchase  stock  or  securities   convertible  or
exchangeable for stock hereafter made by the Company to its  stockholders  shall
not be taxable.

                  (h)  Whenever  the Per  Share  Warrant  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants in accordance  with this Section 3, the Chief  Financial  Officer of
the Company shall  promptly  prepare a  certificate  setting forth the Per Share
Warrant  Price and the number of Warrant  Shares  after such  adjustment  or the
effect of such  modification  and a brief  statement of the facts requiring such
adjustment or modification and the manner of computing the same and cause copies
of such certificate to be mailed to the Holders of the Warrants. In the event of
a dispute with  respect to any  adjustment  required  pursuant to Section 3, the
Holder may appoint, at the Company's expense,  an independent  financial advisor
(e.g. an  investment  banking or  accounting  firm)reasonably  acceptable to the
Company to calculate such adjustment.  Such determination  shall be binding upon
the Holder and the Company.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 15 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the  allocation of the adjusted Per Share Warrant Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  4. Fully Paid Stock; Taxes. The Company agrees that the shares
of the Common Stock  represented by each and every certificate of Warrant Shares
delivered  on the exercise of this  Warrant be validly  issued and  outstanding,
fully paid and nonassessable,  and not subject to preemptive rights or rights of
first refusal, and the Company will take all such actions as may be necessary to
assure that the par value or stated value, if any, per share of the Common Stock
is at all  times  equal to or less than the then Per Share  Warrant  Price.  The
Company further covenants and agrees that it will pay, when due and payable, any
and all Federal and state stamp,  original  issue or similar  taxes which may be
payable in respect of the issue of any Warrant Share or any certificate thereof.

                  5. Registration Under Securities Act of 1933.

                  (a) The Company shall include the Warrant  Shares on the Shelf
Registration  Statement  (as  defined in the Term  Sheet)  and the Holder  shall
otherwise  have  the  registration   rights  set  forth  in  Section  5  of  the
subscription agreement (the "Subscription Agreement") to be entered into between
the purchasers of units (as described in the Term

                                                     - 6 -

M


<PAGE>


Sheet) and the Company. By acceptance of this Warrant, the Holder agrees that it
shall have the same  obligations,  and otherwise  comply with, the provisions in
such  Section 5 of the  Subscription  Agreement  to same  extent as if it were a
party  thereto.  To the extent  that no Final  Closing  Date (as  defined in the
Subscription Agreement) occurs or the Offering is terminated, the rights granted
to Holder hereunder to have its shares  registered shall begin as of December 6,
1997 on the same terms as provided in Section 5 of the Subscription Agreement.

                  (b)  Until  all   Warrant   Shares  have  been  sold  under  a
Registration  Statement  or  pursuant  to Rule 144,  the  Company  shall use its
reasonable best efforts to file with the Securities and Exchange  Commission all
current  reports and the information as may be necessary to enable the Holder to
effect sales of its shares in reliance upon Rule 144 promulgated under the Act.

                  6.  Limited  Transferability.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws.
The Company may treat the registered  Holder of this Warrant as he or it appears
on the Company's  books at any time as the Holder for all purposes.  The Company
shall  permit  any  Holder of a Warrant or his duly  authorized  attorney,  upon
written  request during  ordinary  business  hours,  to inspect and copy or make
extracts from its books showing the registered holders of Warrants. All warrants
issued upon the  transfer or  assignment  of this Warrant will be dated the same
date as this Warrant, and all rights of the holder thereof shall be identical to
those of the Holder.

                  7.  Loss,   etc.,   of  Warrant.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  8.  Warrant  Holder  Not  Shareholder.   Except  as  otherwise
provided herein,  this Warrant does not confer upon the Holder any right to vote
or to consent to or receive notice as a stockholder of the Company,  as such, in
respect of any  matters  whatsoever,  or any other  rights or  liabilities  as a
stockholder, prior to the exercise hereof.

                  9. Communication.  No notice or other communication under this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:

                  (a) the Company at 3550 General  Atomics Court,  San Diego, CA
92121:  President or other  address as the Company has  designated in writing to
the Holder, or

                  (b) the  Holder at c/o  Paramount  Capital  Asset  Management,
Inc., 787 Seventh Avenue, New York, NY, 10019, Attn: Lindsay A. Rosenwald,  M.D.
or other such address as the Holder has designated in writing to the Company.


                                     - 7 -

<PAGE>

                  10. Headings.  The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.

                  11.  Applicable  Law.  This  Warrant  shall be governed by and
construed in  accordance  with the law of the State of New York  without  giving
effect to the principles of conflicts of law thereof.


                                      - 8 -

<PAGE>

         IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by
its President and its corporate seal to be hereunto  affixed and attested by its
Secretary this 6th day of June 1997.


                                               GENTA INCORPORATED


                                               By: _______________________
                                               Name:
                                               Title:

ATTEST:



- -------------------------------
         Secretary

[Corporate Seal]


                                      - 9 -
<PAGE>

                                  SUBSCRIPTION
                                  ------------

         The undersigned, ___________________, pursuant to the provisions of the
foregoing    Warrant,    hereby   agrees   to   subscribe   for   and   purchase
____________________  shares of the Common Stock,  par value $.001 per share, of
Genta Incorporated  covered by said Warrant,  and makes payment therefor in full
at the price per share provided by said Warrant.

Dated:_______________                       Signature:____________________

                                            Address:______________________



                                CASHLESS EXERCISE
                                -----------------

         The undersigned ___________________,  pursuant to the provisions of the
foregoing Warrant, hereby elects to exchange its Warrant for ___________________
shares of  Common  Stock,  par value  $.001  per  share,  of Genta  Incorporated
pursuant to the Cashless Exercise provisions of the Warrant.

Dated:_______________                       Signature:____________________

                                            Address:______________________



                                   ASSIGNMENT
                                   -----------

         FOR VALUE RECEIVED  _______________ hereby sells, assigns and transfers
unto  ____________________  the  foregoing  Warrant  and  all  rights  evidenced
thereby,  and does  irrevocably  constitute  and appoint  _____________________,
attorney, to transfer said Warrant on the books of Genta Incorporated.

Dated:_______________                       Signature:____________________

                                            Address:______________________


<PAGE>

                               PARTIAL ASSIGNMENT
                               ------------------

         FOR VALUE  RECEIVED  _______________  hereby assigns and transfers unto
____________________  the right to purchase  _______ shares of the Common Stock,
par value  $.001 per  share,  of Genta  Incorporated  covered  by the  foregoing
Warrant,  and a  proportionate  part of said  Warrant  and the rights  evidenced
thereby,  and does  irrevocably  constitute  and  appoint  ____________________,
attorney,  to  transfer  that  part  of  said  Warrant  on the  books  of  Genta
Incorporated.

Dated:_______________                       Signature:____________________

                                            Address:______________________


<PAGE>

                                    EXHIBIT P


                                     AMENDED

                           CERTIFICATE OF DESIGNATION

                                       for

                      SERIES D CONVERTIBLE PREFERRED STOCK

                                       of

                               GENTA INCORPORATED

                         Pursuant to Section 151 of the
                General Corporation Law of the State of Delaware


                  GENTA INCORPORATED, a corporation organized and existing under
the laws of the State of Delaware (the "Corporation"), does hereby certify that:

                  FIRST:  Pursuant to a Certificate of Designation  for Series D
         Convertible  Preferred  Stock filed with the  Secretary of State of the
         State of Delaware on February  6, 1997 (the  "Original  Certificate  of
         Designation"),  the Corporation  established a series of its authorized
         preferred  stock,  par value  $.001  per  share,  designated  "Series D
         Convertible Preferred Stock" consisting of 3,750,000 shares.

                  SECOND:  None of the authorized shares of the Corporation's 
         Series D Convertible  Preferred  Stock  established  pursuant to the
         Original Certificate of Designation has been issued.

                  THIRD:  In accordance with the provisions of Section 151(g) of
         the General  Corporation  Law of the State of Delaware,  at a duly held
         meeting of the Board of Directors of the Corporation,  resolutions were
         adopted  decreasing  the number of shares  designated  in the  Original
         Certificate of Designation as Series D Preferred Stock and amending and
         restating  in their  entirety  the  powers,  preferences  and  relative
         participating,   optional  and  other   special   rights  of,  and  the
         qualifications,   limitations  and  restrictions  upon,  the  Series  D
         Convertible Preferred Stock, as set forth herein.

                  NOW, THEREFORE,  IT IS RESOLVED,  that the number of shares of
         the  Corporation's  authorized  preferred  stock,  par value  $.001 per
         share, designated in the Original Certificate of Designation as "Series
         D Convertible Preferred Stock" shall be




<PAGE>



         223,860  (hereinafter the "Series D Preferred Stock"),  and the powers,
         preferences  and relative  participating,  optional  and other  special
         rights of, and the  qualifications,  limitations and restrictions upon,
         the Series D Preferred  Stock are hereby  amended in their entirety and
         shall be, as follows:

                      Series D Convertible Preferred Stock

                  1. Designation and Amount and Definitions.  (a) There shall be
a series of Preferred Stock designated as "Series D Convertible Preferred Stock"
and the number of shares constituting such series shall be 223,860.  Such series
is referred to herein as the "Series D  Preferred  Stock".  Notwithstanding  any
other  provision in the  Certificate  of  Designation  of the Series D Preferred
Stock, as amended hereby,  (the  "Certificate of  Designation") to the contrary,
such series shall be on a parity with the Series A Preferred  Stock and Series C
Preferred  Stock  of  the   Corporation   with  respect  to  dividends  and  the
distribution of assets upon liquidation,  dissolution or winding up. Such number
of shares may be increased or decreased by resolution of the Board of Directors;
provided,  however, that no decrease shall reduce the number of shares of Series
D  Preferred  Stock  to  fewer  than  the  number  of  shares  then  issued  and
outstanding.

                  (b) As used in this Certificate of Designation, the following 
terms shall have the following meanings:

                           (i) The "Closing Bid Price" for any security for each
                  trading day shall be the reported per share  closing bid price
                  of such  security  regular  way on the  Stock  Market  on such
                  trading day, or, if there were no transactions on such trading
                  day, the average of the reported closing bid and asked prices,
                  regular way, of such security on the relevant  Stock Market on
                  such trading day.

                           (ii) "Fair Market Value" of any asset  (including any
                  security)  means the fair  market  value  thereof as  mutually
                  determined by the Corporation and the holders of a majority of
                  the  Series  D  Preferred  Stock  then  outstanding.   If  the
                  Corporation  and the  holders  of a  majority  of the Series D
                  Preferred Stock then outstanding are unable to reach agreement
                  on any valuation matter,  such valuation shall be submitted to
                  and   determined  by  a  nationally   recognized   independent
                  investment  bank  selected by the Board of  Directors  and the
                  holders of a majority  of the  Series D  Preferred  Stock then
                  outstanding  (or,  if such  selection  cannot be  agreed  upon
                  promptly, or in any event within ten days, then such valuation
                  shall  be  made  by  a   nationally   recognized   independent
                  investment  banking firm selected by the American  Arbitration
                  Association  in New York City in  accordance  with its rules),
                  the  costs  of  which  valuation  shall  be  paid  for  by the
                  Corporation.

                           (iii) "Market  Price" shall mean the average  Closing
                  Bid Price for twenty (20)  consecutive  trading  days,  ending
                  with the  trading day prior to the date as of which the Market
                  Price is being determined (with appropriate adjustments

                                       -2-



<PAGE>



                  for  subdivisions  or  combinations  of shares effected during
                  such period),  provided that if the prices  referred to in the
                  definition of Closing Bid Price cannot be determined  for such
                  period, "Market Price" shall mean Fair Market Value.

                           (iv) "Registered Holders" shall mean, at any time, 
                  the holders of record of the Series D Preferred Stock.

                           (v) The "Stock  Market"  shall mean,  with respect to
                  any security,  the principal national  securities  exchange on
                  which such  security  is listed or  admitted to trading or, if
                  such  security  is not  listed or  admitted  to trading on any
                  national securities  exchange,  shall mean The Nasdaq National
                  Market  System  ("NNM") or The Nasdaq  SmallCap  Market ("SCM"
                  and, together with NNM,  "Nasdaq") or, if such security is not
                  quoted on  Nasdaq,  shall mean the OTC  Bulletin  Board or, if
                  such security is not quoted on the OTC Bulletin  Board,  shall
                  mean the  over-the-counter  market  as  furnished  by any NASD
                  member firm selected from time to time by the  Corporation for
                  that purpose.

                           (vi) "Trading  Price" shall mean the lower of (i) the
                  average   Closing   Bid  Price  of  the  Common   Stock  (with
                  appropriate  adjustments  for  subdivisions or combinations of
                  shares   effected   during   such   period)  for  thirty  (30)
                  consecutive trading days, ending with the trading day prior to
                  the date as of which the  Trading  Price is being  determined,
                  and (ii) the  average  Closing  Bid Price of the Common  Stock
                  (with appropriate adjustments for subdivisions or combinations
                  of  shares   effected   during  such   period)  for  five  (5)
                  consecutive trading days, ending with the trading day prior to
                  the date as of which the  Trading  Price is being  determined,
                  provided that if the prices  referred to in the  definition of
                  Closing  Bid  Price  cannot  be  determined  for  any of  such
                  periods, "Trading Price" shall mean Fair Market Value.

                           (vii) A  "trading  day" shall mean a day on which the
                  relevant Stock Market is open for the transaction of business.

                  2.  Dividends and  Distributions.  (a) Commencing on the Reset
Date (as  defined in  Subsection  4(a)),  the  holders of the Series D Preferred
Stock shall be entitled to receive cumulative  dividends on each share of Series
D Preferred  Stock,  payable in shares of Common  Stock,  at the rate of 10% per
annum  (computed  on the basis of a 360-day year of twelve 30 day months) of the
Dividend Base Amount (as defined below),  payable semi-annually in arrears. Such
dividends shall be paid in duly authorized, fully paid and non assessable shares
of Common Stock.  In calculating the number of shares of Common Stock to be paid
with  respect to each  dividend,  each share of Common  Stock shall be deemed to
have the value of the  Conversion  Price (as defined in Section  4(a) hereof) at
the time such  dividend is paid.  Such  dividends  shall  accrue and  accumulate
whether or not they have been  declared  and  whether or not there are  profits,
surplus or other funds of the Corporation legally available for the payment

                                       -3-



<PAGE>



of dividends.  The "Dividend  Base Amount" shall be $140.00 plus all accrued but
unpaid dividends (subject to appropriate  adjustment to reflect any stock split,
combination,  reclassification  or  reorganization  of the  Series  D  Preferred
Stock).

                  (b) In addition to the foregoing, subject to the rights of the
holders of any shares of any series or class of capital stock ranking prior, and
superior  to, or pari passu with,  the shares of Series D  Preferred  Stock with
respect to dividends, the holders of shares of Series D Preferred Stock shall be
entitled to receive, as, when and if declared by the Board of Directors,  out of
assets legally  available for that purpose,  dividends or distributions in cash,
stock or otherwise.

                  (c)  The  Corporation   shall  not  declare  any  dividend  or
distribution  on any Junior Stock (as defined below) of the  Corporation  unless
and until a special  dividend or  distribution  of $140.00 per share (subject to
appropriate adjustment to reflect any stock split, combination, reclassification
or reorganization of the Series D Preferred Stock) has been declared and paid on
the  Series D  Preferred  Stock.  In the event  that such  special  dividend  or
distribution is declared and paid on the Series D Preferred  Stock, an aggregate
per share  dividend or  distribution  equal to (i)  $140.00  divided by (ii) the
effective  Conversion  Rate  (as  defined  below)  at the  time of such  special
dividend or  distribution  on the Series D Preferred  Stock may be declared  and
paid on the Common Stock. Except as aforesaid, the Corporation shall not declare
any dividend or  distribution  on any Junior Stock or stock on a parity with the
Series D Preferred Stock,  unless the Corporation  shall,  concurrently with the
declaration of such dividend or  distribution  on the Junior Stock or stock on a
parity  with  the  Series  D  Preferred  Stock,   declare  a  like  dividend  or
distribution, as the case may be, on the Series D Preferred Stock.

                  (d) Any dividend or  distribution  (other than that referenced
in the first sentence of Subsection 2(c)) payable to the holders of the Series D
Preferred  Stock pursuant to this Section 2 shall be paid to such holders at the
same time as the  dividend  or  distribution  on the  Junior  Stock or any other
capital stock of the Corporation by which it is measured is paid.

                  (e) All dividends or distributions  declared upon the Series D
Preferred Stock shall be declared pro rata per share.

                  (f) Any reference to "distribution"  contained in this Section
2 shall not be deemed to include any distribution  made in connection with or in
lieu of any Liquidation Event (as defined below).

                  (g) No interest, or sum of money in lieu of interest, shall be
payable in respect of any dividend payment or payments on the Series D Preferred
Stock which may be in arrears.

                  (h) So long as any shares of the Series D Preferred  Stock are
outstanding,  no dividends, except as described in the next succeeding sentence,
shall be declared or paid or set

                                       -4-



<PAGE>



apart for payment on any class or series of stock of the Corporation ranking, as
to  dividends,  on a parity  with the Series D Preferred  Stock,  for any period
unless all dividends  have been or  contemporaneously  are declared and paid, or
declared  and a sum  sufficient  for the  payment  thereof  set  apart  for such
payment, on the Series D Preferred Stock. When dividends are not paid in full or
a sum  sufficient  for such  payment is not set apart,  as  aforesaid,  upon the
shares of the Series D  Preferred  Stock and any other  class or series of stock
ranking on a parity as to  dividends  with the  Series D  Preferred  Stock,  all
dividends  declared upon such other stock shall be declared pro rata so that the
amounts of dividends per share declared on the Series D Preferred Stock and such
other  stock  shall in all cases bear to each other the same ratio that  accrued
dividends  per share on the shares of the Series D  Preferred  Stock and on such
other stock bear to each other.

                  (i) So long as any shares of the Series D Preferred  Stock are
outstanding,  no other  stock of the  Corporation  ranking on a parity  with the
Series D Preferred  Stock as to dividends or upon  liquidation,  dissolution  or
winding  up  shall  be  redeemed,   purchased  or  otherwise  acquired  for  any
consideration  (or any moneys be paid to or made available for a sinking fund or
otherwise for the purchase or redemption of any shares of any such stock) by the
Corporation  unless the dividends,  if any, accrued on all outstanding shares of
the Series D Preferred Stock shall have been paid or set apart for payment.

                  (j) "Junior  Stock" shall mean the Common Stock and any shares
of preferred stock of any series or class of the Corporation,  whether presently
outstanding  or  hereafter  issued,  which are  junior to the shares of Series D
Preferred Stock with respect to (i) the  distribution of assets on any voluntary
or involuntary liquidation,  dissolution or winding up of the Corporation,  (ii)
dividends  or (iii)  voting,  except that the Junior Stock shall not include the
Series A Preferred Stock nor the Series C Preferred Stock of the Corporation.

Notwithstanding the foregoing, this Section 2 shall only be effective insofar as
it does not conflict  with any  provision of the  Certificate  of  Incorporation
relating to the rights of the Series A Preferred  Stock,  and does not cause the
Series D  Preferred  Stock to be senior to the  Series A  Preferred  Stock  with
respect to dividends.

                  3.  Liquidation  Preference.   (a)  In  the  event  of  a  (i)
liquidation,  dissolution or winding up of the Corporation, whether voluntary or
involuntary, (ii) a sale or other disposition of all or substantially all of the
assets of the  Corporation  or (iii)  any  consolidation,  merger,  combination,
reorganization  or  other  transaction  in  which  the  Corporation  is not  the
surviving entity or shares of Common Stock  constituting in excess of 50% of the
voting  power of the  Corporation  are  exchanged  for or changed  into stock or
securities  of  another  entity,  cash  and/or  any other  property  (a  "Merger
Transaction")  (items (i),  (ii) and (iii) of this sentence  being  collectively
referred to as a "Liquidation Event"), after payment or provision for payment of
debts and other  liabilities of the Corporation and subject to the Corporation's
prior  compliance  with  Article IV of the  Certificate  of  Incorporation,  the
holders of the Series D Preferred Stock then outstanding shall be entitled to be
paid out of the assets of the Corporation available for

                                       -5-



<PAGE>



distribution to its stockholders on a pari passu basis with the shares of Series
A Preferred Stock and Series C Preferred Stock of the Corporation,  whether such
assets are capital,  surplus, or earnings, before any payment or declaration and
setting  apart for payment of any amount  shall be made in respect of any Junior
Stock of the  Corporation,  an amount  equal to $140.00 per share plus an amount
equal to all declared and/or unpaid dividends thereon; provided, however, in the
case of a  Merger  Transaction,  such  $140.00  per  share  may be paid in cash,
property  (valued as provided in Subsection 3(b)) and/or  securities  (valued as
provided in Subsection 3(b)) of the entity surviving such Merger Transaction. In
the case of property or in the event that any such  securities are subject to an
investment letter or other similar restriction on transferability,  the value of
such  property  or  securities  shall be  determined  by  agreement  between the
Corporation  and the holders of a majority of the Series D Preferred  Stock then
outstanding.  If upon any Liquidation  Event,  whether voluntary or involuntary,
the assets to be  distributed  to the  holders of the Series D  Preferred  Stock
shall be  insufficient  to permit the payment to such  shareholders  of the full
preferential amounts aforesaid,  then all of the assets of the Corporation to be
distributed  shall be so  distributed  ratably  to the  holders  of the Series D
Preferred Stock on the basis of the number of shares of Series D Preferred Stock
held.  Notwithstanding item (iii) of the first sentence of this Subsection 3(a),
any consolidation,  merger, combination,  reorganization or other transaction in
which the  Corporation is not the surviving  entity but the  stockholders of the
Corporation  immediately  prior to such  transaction own in excess of 50% of the
voting power of the corporation surviving such transaction and own such interest
in substantially the same proportions as prior to such transaction, shall not be
considered a Liquidation  Event  provided that the surviving  corporation  shall
make  appropriate  provisions  to ensure that the terms of this  Certificate  of
Designation survive any such transaction as provided in Subsection 4(c)(ii). All
shares of Series D Preferred  Stock shall rank as to payment upon the occurrence
of any  Liquidation  Event senior to the Common Stock as provided  herein,  on a
pari  passu  basis  with the  shares of Series A  Preferred  Stock and  Series C
Preferred  Stock of the  Corporation,  and unless the terms of such series shall
provide  otherwise,  senior to all other series of the  Corporation's  preferred
stock.

                  (b) Any  securities  or other  property to be delivered to the
holders of the Series D Preferred Stock pursuant to Subsection 3(a) hereof shall
be valued as follows:

                           (i)      Securities not subject to an investment 
                  letter or other similar restriction on free marketability:

                                    (A) If  actively  traded on a Stock  Market,
                           the value  shall be deemed to be the Market  Price as
                           of the third day prior to the date of valuation.

                                    (B)  If  not  actively  traded  on  a  Stock
                           Market, the value shall be the Fair Market Value.


                                       -6-



<PAGE>



                           (ii) For  securities  for  which  there is an  active
                  public market but which are subject to an investment letter or
                  other restrictions on free  marketability,  the value shall be
                  the Fair  Market  Value  thereof,  determined  by  discounting
                  appropriately the Market Price thereof.

                           (iii) For all other  securities,  the value  shall be
                  the Fair Market Value thereof.

                  4.       Conversion.

                  (a) Right of  Conversion.  The  shares  of Series D  Preferred
Stock  shall be  convertible,  in whole or in part,  at the option of the holder
thereof and upon notice to the Corporation as set forth in Subsection 4(b), into
fully paid and  nonassessable  shares of Common Stock and such other  securities
and property as hereinafter provided.  The initial conversion price per share of
Common  Stock  shall be equal to $3.00  (the  "Conversion  Price")  and shall be
subject to adjustment as provided herein.  The rate at which each share Series D
Preferred  Stock is convertible  at any time into Common Stock (the  "Conversion
Rate") shall be determined by dividing the then existing  Conversion  Price into
$100.00.

                  Subject to adjustment pursuant to the provisions of Subsection
4(c) below, in the event that the Conversion  Price in effect at the time of the
Initial  Closing Date (as defined  below),  any Interim Closing Date (as defined
below) or the Final  Closing Date (as defined  below) is greater than 50% of the
Trading  Price of the Common  Stock as of (x) the  initial  closing  date of the
issuance and sale of units (the "Premium  Preferred Units") consisting of Series
D Preferred  Stock and Class D Warrants  pursuant to a  confidential  term sheet
dated May 20, 1997 (the "Initial Closing Date"), (y) any interim closing date of
the issuance and sale of the Premium  Preferred Units (each an "Interim  Closing
Date") or (z) the final  closing  date of the  issuance  and sale of the Premium
Preferred  Units  (the  "Final  Closing  Date")  pursuant  to  the  subscription
agreements entered into in connection therewith, then the Conversion Price shall
be adjusted to equal 50% of the lesser of any such  Trading  Price.  If there is
any change in Conversion Price as a result of the preceding  sentence,  then the
Conversion  Rate shall be changed  accordingly as set forth above.  In the event
that there is no Initial,  Interim nor Final Closing Date (as defined above), or
the  above  referenced   offering  of  Premium   Preferred  Units  is  otherwise
terminated,  then  "Initial  Closing  Date",  "Interim  Closing Date" and "Final
Closing  Date" as used  herein  shall  refer to the  initial,  interim and final
closing date, respectively, in the next offering or series of related offerings)
of equity  securities of the  Corporation  (or any securities  convertible  into
equity  securities)("Qualified  Offering  Securities")  with gross  proceeds  in
excess of $2,000,000.

                  The Board of  Directors,  or a committee  designated by it for
such purpose,  may specify an initial  conversion price applicable to the shares
of  Series D  Preferred  Stock  issued at any  closing  lower  than the  initial
conversion price that would otherwise obtain pursuant to the

                                       -7-



<PAGE>



preceding  paragraphs  of this  Subsection  4(a) and,  in the  event an  initial
conversion  price is so  specified,  it shall be applicable to all shares of the
Series D Preferred Stock.

                  The  Corporation  shall  prepare a  certificate  signed by the
Chairman or  President,  and by the  Treasurer or an Assistant  Treasurer or the
Secretary  or an  Assistant  Secretary,  of the  Corporation  setting  forth the
Conversion Rate as of the Final Closing Date,  showing in reasonable  detail the
facts upon which such adjusted  Conversion Rate is based,  and such  certificate
shall  forthwith  be filed with the  transfer  agent of the  Series D  Preferred
Stock. A notice stating that the Conversion  Rate has been adjusted  pursuant to
the second preceding paragraph of this Subsection 4(a), or that no adjustment is
necessary,  and  setting  forth  the  Conversion  Rate in effect as of the Final
Closing Date shall be mailed as promptly as practicable  after the Final Closing
Date by the Corporation to all record holders of the Series D Preferred Stock at
their last  addresses  as they shall appear in the stock  transfer  books of the
Corporation.

                  The Conversion  Price  (subject to adjustment  pursuant to the
provisions of Subsection 4(c)) in effect  immediately  prior to the date that is
12 months after the Final  Closing Date (the "Reset Date") shall be adjusted and
reset  effective  as of the Reset Date if the Market  Price as of the Reset Date
(the  "12-Month  Trading  Price")  is  less  than  140% of the  then  applicable
Conversion  Price (a "Reset Event").  Upon the occurrence of a Reset Event,  the
Conversion Price shall be reduced to be equal to the greater of (A) the 12-Month
Trading Price  divided by 1.40,  and (B) 25% of the then  applicable  Conversion
Price.  If there  is any  change  in the  Conversion  Price  as a result  of the
preceding sentence, then the Conversion Rate shall be changed accordingly as set
forth above. The Corporation shall prepare a certificate signed by the principal
financial officer of the Corporation setting forth the Conversion Rate as of the
Reset Date,  showing in reasonable  detail the facts upon which such  Conversion
Rate is based, and such  certificate  shall forthwith be filed with the transfer
agent of the Series D Preferred Stock. A notice stating that the Conversion Rate
has  been  adjusted  pursuant  to  this  paragraph,  or that  no  adjustment  is
necessary,  and setting forth the Conversion Rate in effect as of the Reset Date
shall  be  mailed  as  promptly  as  practicable  after  the  Reset  Date by the
Corporation to all record holders of the Series D Preferred  Stock at their last
addresses as they shall appear in the stock transfer books of the Corporation.

                  (b)  Conversion  Procedures.  Any holder of shares of Series D
Preferred  Stock  desiring  to convert  such  shares  into  Common  Stock  shall
surrender the  certificate or  certificates  evidencing  such shares of Series D
Preferred  Stock at the office of the transfer  agent for the Series D Preferred
Stock,  which certificate or certificates,  if the Corporation shall so require,
shall be duly endorsed to the  Corporation or in blank, or accompanied by proper
instruments  of  transfer  to  the  Corporation  or  in  blank,  accompanied  by
irrevocable  written  notice to the  Corporation  that the  holder  elects so to
convert such shares of Series D Preferred Stock and specifying the name or names
(with  address) in which a  certificate  or  certificates  evidencing  shares of
Common  Stock  are to be  issued.  The  Corporation  need not  deem a notice  of
conversion to be received  unless the holder  complies  with all the  provisions
hereof.  The  Corporation  will  instruct the  transfer  agent (which may be the
Corporation) to make a notation

                                       -8-



<PAGE>



of the date that a notice of conversion is received,  which date shall be deemed
to be the date of receipt for purposes hereof.

                  The  Corporation  shall,  as soon as  practicable  after  such
deposit  of  certificates   evidencing   shares  of  Series  D  Preferred  Stock
accompanied  by the  written  notice and  compliance  with any other  conditions
herein  contained,  deliver at such office of such transfer  agent to the person
for whose account such shares of Series D Preferred  Stock were so  surrendered,
or to the nominee or nominees of such person, certificates evidencing the number
of full  shares  of Common  Stock to which  such  person  shall be  entitled  as
aforesaid,  together  with a cash  adjustment  of any  fraction  of a  share  as
hereinafter  provided.  Subject to the following  provisions of this  paragraph,
such  conversion  shall  be  deemed  to have  been  made as of the  date of such
surrender  of the shares of Series D Preferred  Stock to be  converted,  and the
person or  persons  entitled  to  receive  the  Common  Stock  deliverable  upon
conversion of such Series D Preferred Stock shall be treated for all purposes as
the  record  holder or  holders of such  Common  Stock on such  date;  provided,
however,  that the  Corporation  shall not be  required to convert any shares of
Series D Preferred  Stock while the stock transfer books of the  Corporation are
closed  for any  purpose,  but the  surrender  of Series D  Preferred  Stock for
conversion  during  any  period  while  such  books are so closed  shall  become
effective for conversion  immediately upon the reopening of such books as if the
surrender had been made on the date of such reopening,  and the conversion shall
be at the  conversion  rate in effect on such date. No adjustments in respect of
any dividends on shares surrendered for conversion or any dividend on the Common
Stock issued upon conversion  shall be made upon the conversion of any shares of
Series D Preferred Stock.

                  The Corporation shall at all times, reserve and keep available
out of its  authorized  but  unissued  shares of Common  Stock,  solely  for the
purpose of effecting the  conversion of the shares of Series D Preferred  Stock,
such number of shares of Common  Stock as shall from time to time be  sufficient
to effect the  conversion  of all  outstanding  shares of the Series D Preferred
Stock.

                  All  notices of  conversion  shall be  irrevocable;  provided,
however,  that if the  Corporation  has  sent  notice  of an event  pursuant  to
Subsection  4(g)  hereof,  a holder  of Series D  Preferred  Stock  may,  at its
election,  provide in its notice of conversion that the conversion of its shares
of Series D  Preferred  Stock shall be  contingent  upon the  occurrence  of the
record  date or  effectiveness  of such  event (as  specified  by such  holder),
provided that such notice of conversion is received by the Corporation  prior to
such record date or effective date, as the case may be.

                  (c)      Adjustment of Conversion Rate and Conversion Price.

                           (i)      Except as otherwise provided herein, in the 
event the  Corporation  shall,  at any time or from time to time  after the date
hereof,  (1) sell or issue any shares of Common  Stock for a  consideration  per
share less than either (i) the Conversion Price in effect

                                       -9-



<PAGE>



on the date of such sale or  issuance  or (ii) the  Market  Price of the  Common
Stock as of the date of the sale or  issuance,  (2) issue  any  shares of Common
Stock as a stock  dividend to the holders of Common  Stock,  or (3) subdivide or
combine the  outstanding  shares of Common Stock into a greater or lesser number
of shares (any such sale,  issuance,  subdivision  or  combination  being herein
called a "Change of Shares"),  then, and thereafter  upon each further Change of
Shares,  the  Conversion  Price in effect  immediately  prior to such  Change of
Shares shall be changed to a price  (rounded to the nearest cent)  determined by
multiplying  the  Conversion  Price in effect  immediately  prior  thereto  by a
fraction,  the  numerator  of which  shall be the sum of the number of shares of
Common  Stock  outstanding  immediately  prior to the sale or  issuance  of such
additional shares or such subdivision or combination and the number of shares of
Common Stock which the aggregate  consideration received (determined as provided
in Subparagraph  4(c)(v)(F))  for the issuance of such  additional  shares would
purchase  at the  greater of (i) the  Conversion  Price in effect on the date of
such issuance or (ii) the Market Price of the Common Stock as of such date,  and
the  denominator  of  which  shall be the  number  of  shares  of  Common  Stock
outstanding  immediately after the sale or issuance of such additional shares or
such  subdivision or  combination.  Such adjustment  shall be made  successively
whenever such an issuance is made.

                           (ii)     In case of any reclassification, capital 
reorganization or other change of outstanding shares of Common Stock, or in case
of any  consolidation  or merger of the Corporation  with or into another entity
(other than a consolidation or merger in which the Corporation is the continuing
entity and which does not result in any reclassification, capital reorganization
or other  change of  outstanding  shares of Common  Stock  other than the number
thereof), or in case of any sale or conveyance to another entity of the property
of  the  Corporation  as,  or  substantially  as,  an  entirety  (other  than  a
sale/leaseback,  mortgage or other financing transaction), the Corporation shall
cause effective  provision to be made so that each holder of a share of Series D
Preferred  Stock shall be entitled to receive,  upon conversion of such share of
Series D  Preferred  Stock,  the kind and  number  of  shares  of stock or other
securities or property  (including cash) receivable upon such  reclassification,
capital  reorganization  or  other  change,   consolidation,   merger,  sale  or
conveyance  by a holder of the number of shares of Common  Stock into which such
share of Series D  Preferred  Stock was  convertible  immediately  prior to such
reclassification, capital reorganization or other change, consolidation, merger,
sale or conveyance.  Any such provision shall include  provision for adjustments
that shall be as nearly  equivalent  as may be  practicable  to the  adjustments
provided for in this Subsection 4(c). The Corporation  shall not effect any such
consolidation,  merger  or sale  unless  prior  to or  simultaneously  with  the
consummation  thereof the  successor (if other than the  Corporation)  resulting
from  such  consolidation  or merger or the  entity  purchasing  assets or other
appropriate entity shall assume, by written instrument executed and delivered to
the transfer agent for the Series D Preferred Stock (the "Transfer Agent"),  the
obligation  to deliver to the holder of each share of Series D  Preferred  Stock
such shares of stock,  securities or assets as, in accordance with the foregoing
provisions,  such  holders may be entitled to receive and the other  obligations
under this Agreement. The foregoing provisions shall similarly apply to

                                      -10-



<PAGE>



successive  reclassifications,  capital  reorganizations  and other  changes  of
outstanding  shares of Common Stock and to successive  consolidations,  mergers,
sales or conveyances.

                           (iii)    [Reserved]

                           (iv)     After each adjustment of the Conversion 
Price pursuant to this Subsection  4(c), the Corporation will promptly prepare a
certificate  signed by the  Chairman or  President,  and by the  Treasurer or an
Assistant  Treasurer  or  the  Secretary  or  an  Assistant  Secretary,  of  the
Corporation  setting forth:  (i) the Conversion  Price as so adjusted,  (ii) the
Conversion Rate  corresponding to such Conversion and (iii) a brief statement of
the facts  accounting for such  adjustment.  The Corporation  will promptly file
such certificate with the Transfer Agent and cause a brief summary thereof to be
sent by  ordinary  first  class  mail to each  registered  holder  of  Series  D
Preferred  Stock at his or her last  address as it shall  appear on the registry
books of the  Transfer  Agent.  No  failure  to mail such  notice nor any defect
therein or in the mailing thereof shall affect the validity of such  adjustment.
The  affidavit  of an  officer  of the  Transfer  Agent or the  Secretary  or an
Assistant  Secretary of the Corporation  that such notice has been mailed shall,
in the absence of fraud,  be prima facie  evidence of the facts stated  therein.
The Transfer Agent may rely on the  information  in the  certificate as true and
correct and has no duty or  obligation  to  independently  verify the amounts or
calculations set forth therein.

                           (v)      For purposes of Subsection 4(c)(i) hereof, 
the following provisions (A) to (F) shall also be applicable:

                                    (A) The  number of  shares  of Common  Stock
                           deemed  outstanding  at any given time shall  include
                           all  shares of capital  stock  convertible  into,  or
                           exchangeable  for,  Common  Stock (on an as converted
                           basis) as well as all shares of Common Stock issuable
                           upon the exercise of (x) any  convertible  debt,  (y)
                           warrants  outstanding  on the  date  hereof  and  (z)
                           options outstanding on the date hereof.

                                    (B) No  adjustment of the  Conversion  Price
                           shall be made unless such adjustment would require an
                           increase  or decrease of at least $.01 in such price;
                           provided that any adjustments which by reason of this
                           Subparagraph (B) are not required to be made shall be
                           carried  forward and shall be made at the time of and
                           together with the next subsequent  adjustment  which,
                           together with adjustments so carried  forward,  shall
                           require an  increase  or decrease of at least $.01 in
                           the Conversion Price then in effect hereunder.

                                    (C)  In  case  of  (1)  the  sale  or  other
                           issuance by the Corporation (including as a component
                           of a unit) of any rights or warrants to subscribe for
                           or  purchase,  or any  options for the  purchase  of,
                           Common Stock or any

                                      -11-



<PAGE>



                           securities   convertible  into  or  exchangeable  for
                           Common    Stock   (such    securities    convertible,
                           exercisable or  exchangeable  into Common Stock being
                           herein called "Convertible  Securities"),  or (2) the
                           issuance by the  Corporation,  without the receipt by
                           the Corporation of any consideration therefor, of any
                           rights or warrants to subscribe  for or purchase,  or
                           any  options for the  purchase  of,  Common  Stock or
                           Convertible  Securities,  whether or not such rights,
                           warrants  or  options,  or the  right to  convert  or
                           exchange such Convertible Securities, are immediately
                           exercisable,  and the  consideration  per  share  for
                           which Common  Stock is issuable  upon the exercise of
                           such   rights,   warrants  or  options  or  upon  the
                           conversion or exchange of such Convertible Securities
                           (determined  by dividing  (x) the  minimum  aggregate
                           consideration,   as  set  forth  in  the   instrument
                           relating  thereto without regard to any  antidilution
                           or  similar   provisions   contained  therein  for  a
                           subsequent adjustment of such amount,  payable to the
                           Corporation   upon  the   exercise  of  such  rights,
                           warrants or options, plus the consideration  received
                           by the  Corporation  for the issuance or sale of such
                           rights,  warrants  or options,  plus,  in the case of
                           such Convertible  Securities,  the minimum  aggregate
                           amount,  as  set  forth  in the  instrument  relating
                           thereto without regard to any antidilution or similar
                           provisions   contained   therein  for  a   subsequent
                           adjustment    of   such   amount,    of    additional
                           consideration,  if any,  other than such  Convertible
                           Securities,  payable upon the  conversion or exchange
                           thereof,  by (y) the  total  maximum  number,  as set
                           forth  in the  instrument  relating  thereto  without
                           regard  to any  antidilution  or  similar  provisions
                           contained therein for a subsequent adjustment of such
                           amount,  of shares of Common Stock  issuable upon the
                           exercise of such rights,  warrants or options or upon
                           the  conversion  or  exchange  of  such   Convertible
                           Securities issuable upon the exercise of such rights,
                           warrants   or   options)  is  less  than  either  the
                           Conversion  Price or the  Market  Price of the Common
                           Stock as of the date of the  issuance or sale of such
                           rights,  warrants or options, then such total maximum
                           number of shares of Common  Stock  issuable  upon the
                           exercise of such rights,  warrants or options or upon
                           the  conversion  or  exchange  of  such   Convertible
                           Securities (as of the date of the issuance or sale of
                           such rights,  warrants or options) shall be deemed to
                           be "Common Stock" for purposes of Subsection  4(c)(i)
                           and  shall be  deemed to have been sold for an amount
                           equal to such consideration per share and shall cause
                           an  adjustment   to  be  made  in   accordance   with
                           Subsection 4(c)(i).

                                    (D) In case of the  sale by the  Corporation
                           of any  Convertible  Securities,  whether  or not the
                           right  of  conversion   or  exchange   thereunder  is
                           immediately exercisable,  and the price per share for
                           which Common Stock is issuable upon the conversion or
                           exchange of such Convertible  Securities  (determined
                           by dividing (x) the total amount of consideration

                                      -12-



<PAGE>



                           received  by the  Corporation  for  the  sale of such
                           Convertible  Securities,  plus the minimum  aggregate
                           amount,  as  set  forth  in the  instrument  relating
                           thereto without regard to any antidilution or similar
                           provisions   contained   therein  for  a   subsequent
                           adjustment    of   such   amount,    of    additional
                           consideration,  if any,  other than such  Convertible
                           Securities,  payable upon the  conversion or exchange
                           thereof,  by (y) the  total  maximum  number,  as set
                           forth  in the  instrument  relating  thereto  without
                           regard  to any  antidilution  or  similar  provisions
                           contained therein for a subsequent adjustment of such
                           amount,  of shares of Common Stock  issuable upon the
                           conversion   or   exchange   of   such    Convertible
                           Securities) is less than either the Conversion  Price
                           or the  Market  Price of the  Common  Stock as of the
                           date of the sale of such Convertible Securities, then
                           such total  maximum  number of shares of Common Stock
                           issuable  upon the  conversion  or  exchange  of such
                           Convertible Securities (as of the date of the sale of
                           such  Convertible  Securities)  shall be deemed to be
                           "Common Stock" for purposes of Subsection 4(c)(i) and
                           shall be deemed to have been sold for an amount equal
                           to such  consideration  per share and shall  cause an
                           adjustment to be made in accordance  with  Subsection
                           4(c)(i).

                                    (E) In case the Corporation shall modify the
                           rights of conversion,  exchange or exercise of any of
                           the  securities  referred  to in (C) and (D) above or
                           any other securities of the Corporation  convertible,
                           exchangeable  or  exercisable  for  shares  of Common
                           Stock,  for any reason other than an event that would
                           require  adjustment to prevent dilution,  so that the
                           consideration  per share received by the  Corporation
                           after  such  modification  is less  than  either  the
                           Conversion  Price or the Market  Price as of the date
                           prior to such modification,  then such securities, to
                           the extent not  theretofore  exercised,  converted or
                           exchanged,   shall  be  deemed  to  have  expired  or
                           terminated  immediately  prior  to the  date  of such
                           modification and the Corporation  shall be deemed for
                           purposes of calculating any  adjustments  pursuant to
                           this   Subsection   4(c)  to  have  issued  such  new
                           securities  upon  such  new  terms  on  the  date  of
                           modification.  Such adjustment shall become effective
                           as of the date upon  which  such  modification  shall
                           take effect. On the expiration or cancellation of any
                           such right,  warrant or option or the  termination or
                           cancellation of any such right to convert or exchange
                           any such Convertible Securities, the Conversion Price
                           then  in  effect   hereunder   shall   forthwith   be
                           readjusted  to such  Conversion  Price as would  have
                           obtained  (a)  had  the  adjustments  made  upon  the
                           issuance or sale of such rights, warrants, options or
                           Convertible  Securities  been  made upon the basis of
                           the  issuance  of only the number of shares of Common
                           Stock theretofore  actually  delivered (and the total
                           consideration received therefor) upon the exercise of
                           such   rights,   warrants  or  options  or  upon  the
                           conversion or exchange of such

                                      -13-



<PAGE>



                           Convertible  Securities and (b) had adjustments  been
                           made on the basis of the Conversion Price as adjusted
                           under   clause   (a)  of   this   sentence   for  all
                           transactions (which would have affected such adjusted
                           Conversion  Price) made after the issuance or sale of
                           such  rights,   warrants,   options  or   Convertible
                           Securities.

                                    (F) In case of the  sale  of any  shares  of
                           Common Stock, any Convertible Securities,  any rights
                           or  warrants to  subscribe  for or  purchase,  or any
                           options  for  the  purchase   of,   Common  Stock  or
                           Convertible Securities, the consideration received by
                           the  Corporation  therefor  shall be deemed to be the
                           gross  sales   price   therefor   without   deducting
                           therefrom   any  expense  paid  or  incurred  by  the
                           Corporation   or  any   underwriting   discounts   or
                           commissions  or  concessions  paid or  allowed by the
                           Corporation  in  connection  therewith.  In the event
                           that any  securities  shall be issued  in  connection
                           with  any  other   securities  of  the   Corporation,
                           together comprising one integral transaction in which
                           no  specific  consideration  is  allocated  among the
                           securities,  then  each of such  securities  shall be
                           deemed to have been issued for such  consideration as
                           the Board of Directors of the Corporation  determines
                           in  good  faith;   provided,   however  that  if  the
                           Registered  Holders  of in  excess of 25% of the then
                           outstanding  Series D Preferred  Stock  disagree with
                           such determination,  the Corporation shall retain, at
                           its own expense,  an independent  investment  banking
                           firm for the purpose of obtaining an appraisal.

                           (vi)     Notwithstanding any other provision hereof, 
no adjustment to the Conversion Price will be made:

                                    (A) upon the exercise of any of the options 
                           outstanding  on the date hereof under the 
                           Corporation's existing stock option plans; or

                                    (B) upon the issuance or exercise of options
                           which may  hereafter  be granted with the approval of
                           the  Board of  Directors,  or  exercised,  under  any
                           employee benefit plan of the Corporation to officers,
                           directors,  consultants  or employees,  but only with
                           respect to such options as are  exercisable at prices
                           no lower than the Closing Bid Price (or, if the price
                           referenced  in the  definition  of Closing  Bid Price
                           cannot be  determined,  the Fair Market Value) of the
                           Common Stock as of the date of grant thereof; or

                                    (C) upon issuance or exercise of the 
                           Placement  Warrants,  or  the  Advisory  Warrants, 

                           (as defined in the Placement  Agency  Agreement  
                           between the  Corporation  and  Paramount   Capital, 
                           Inc.  (the "Placement

                                      -14-



<PAGE>



                           Agent")  dated  as of May  1,  1997  (the  "Placement
                           Agency  Agreement"))  (collectively,  the  "Paramount
                           Warrants"),  upon  the  conversion  of the  Series  D
                           Preferred  Stock  underlying  the  Bridge  Notes  (as
                           defined in the Note and  Warrant  Purchase  Agreement
                           dated as of January  28,  1997 (the "Note and Warrant
                           Purchase Agreement")), upon the exercise of the Class
                           A and Class B Bridge Warrants (as defined in the Note
                           and Warrant Purchase Agreement) or upon the issuance,
                           conversion  or  exercise  of the  Series D  Preferred
                           Stock or the Class D Warrants included in the Premium
                           Preferred Units of the  Corporation  issued (i) on or
                           prior to the Final  Closing Date or (ii)  pursuant to
                           the exercise of the Paramount  Warrants,  or upon the
                           issuance,  conversion  or  exercise  of any  Series D
                           Preferred  Stock or Class D Warrants  approved by the
                           Placement  Agent or upon the  issuance  of any  other
                           equity  securities of the  Corporation  to the extent
                           that  such  issuance  causes  an  adjustment  to  the
                           Conversion  Price pursuant to the second paragraph of
                           Subsection 4(a); or

                                    (D)  upon  the  issuance  or sale of  Common
                           Stock  or  Convertible  Securities  pursuant  to  the
                           exercise  of  any  rights,  options  or  warrants  to
                           receive,  subscribe  for or purchase,  or any options
                           for the  purchase  of,  Common  Stock or  Convertible
                           Securities,  whether or not such rights,  warrants or
                           options were  outstanding on the date of the original
                           issuance  of the  Series  D  Preferred  Stock or were
                           thereafter   issued   or  sold,   provided   that  an
                           adjustment was either made or not required to be made
                           in accordance with  Subsection  4(c)(i) in connection
                           with the issuance or sale of such  securities  or any
                           modification of the terms thereof; or

                                    (E)  upon  the  issuance  or sale of  Common
                           Stock upon  conversion or exchange of any Convertible
                           Securities, provided that any adjustments required to
                           be made upon the issuance or sale of such Convertible
                           Securities or any  modification  of the terms thereof
                           were so made,  and  whether  or not such  Convertible
                           Securities  were  outstanding  on  the  date  of  the
                           original sale of the Series D Preferred Stock or were
                           thereafter  issued or sold;  or upon the  issuance of
                           Common  Stock  upon   conversion   of  principal  and
                           interest in respect of $350,000  principal  amount of
                           the Company's 4% Convertible Debentures due August 1,
                           1997  outstanding  on  February  6,  1997 or upon the
                           conversion of 1,424 shares of the Company's  Series C
                           Preferred  Stock  outstanding  on  February  6, 1997,
                           provided  that  any  such  conversion   occurs  at  a
                           conversion price in excess of the Conversion Price at
                           such time.

Subparagraph  4(c)(v)(E)  shall  nevertheless  apply to any  modification of the
rights of conversion,  exchange or exercise of any of the securities referred to
in Subparagraphs (A), (B) and (C) of this Subsection 4(c)(vi).

                                      -15-



<PAGE>




                           (vii)    As used in this Subsection 4(c), the term 
"Common Stock" shall mean and include the Corporation's  Common Stock authorized
on the date of the original issue of the Series D Preferred Stock and shall also
include any capital stock of any class of the Corporation  thereafter authorized
which shall not be limited to a fixed sum or percentage in respect of the rights
of the holders  thereof to participate in dividends and in the  distribution  of
assets  upon  the  voluntary  liquidation,  dissolution  or  winding  up of  the
Corporation;  provided, however, that the shares issuable upon conversion of the
Series D Preferred  Stock shall include only shares of such class  designated in
the  Certificate  of  Incorporation  as Common Stock on the date of the original
issue  of  the  Series  D   Preferred   Stock  or  (i),   in  the  case  of  any
reclassification,  change,  consolidation,  merger,  sale or  conveyance  of the
character referred to in Subsection  4(c)(ii) hereof,  the stock,  securities or
property   provided  for  in  such   section  or  (ii),   in  the  case  of  any
reclassification  or change in the  outstanding  shares of Common Stock issuable
upon  conversion of the Series D Preferred Stock as a result of a subdivision or
combination or consisting of a change in par value,  or from par value to no par
value,  or from no par value to par  value,  such  shares of Common  Stock as so
reclassified or changed.

                           (viii)   Any determination as to whether an 
adjustment in the Conversion Price in effect  hereunder is required  pursuant to
Subsection  4(a)  or  4(c),  or as to the  amount  of any  such  adjustment,  if
required,  shall be binding upon the holders of the Series D Preferred Stock and
the  Corporation  if  made  in good  faith  by the  Board  of  Directors  of the
Corporation.

                  (d) No  Fractional  Shares.  No  fractional  shares  or  scrip
representing  fractional  shares of Common Stock shall be issued upon conversion
of Series D Preferred Stock. If more than one certificate  evidencing  shares of
Series D Preferred  Stock shall be surrendered for conversion at one time by the
same holder, the number of full shares issuable upon conversion thereof shall be
computed  on the basis of the  aggregate  number of shares of Series D Preferred
Stock so  surrendered.  Instead of any  fractional  share of Common  Stock which
would  otherwise be issuable upon conversion of any shares of Series D Preferred
Stock, the Corporation shall pay a cash adjustment in respect of such fractional
interest in an amount  equal to the same  fraction of the Market Price as of the
close of business on the day of conversion.

                  (e) Concurrent  Grant. If the  Corporation  shall fix a record
date for the making of a  Distribution  on Common Stock to holders of its Common
Stock (other than any  distribution  referred to in  Subsection  4(c) hereof and
cash dividends paid out of retained earnings of the Corporation determined under
generally accepted accounting principals  consistently applied), the Corporation
shall set aside in an escrow reasonably  acceptable to the holders of the Series
D Preferred  Stock, the Distribution on Common Stock (as defined below) to which
they  would  have  been  entitled  if they  had  converted  all of the  Series D
Preferred  Stock held by them for the  Corporation's  Common  Stock  immediately
prior to the record date for the purpose of determining stockholders entitled to
receive such  Distribution  on Common Stock and any such  Distribution on Common
Stock shall  thereafter be  distributed  from time to time out of such escrow to
persons converting the Series D Preferred Stock (immediately upon conversion) to
the extent such  Distribution  on Common Stock relates to the shares of Series D
Preferred Stock then

                                      -16-



<PAGE>



being converted. As used herein, the term "Distribution on Common Stock" means a
distribution  to holders of the Common Stock  (including  any such  distribution
made in connection  with a  consolidation  or merger in which the Corporation is
the  continuing  corporation)  of (i) assets  (including  any cash  dividends or
distributions),  (ii)  evidences  of  indebtedness  or other  securities  of the
Corporation or of any entity other than the  Corporation  or (iii)  subscription
rights,  options  or  warrants  to  purchase  any of  the  foregoing  assets  or
securities,  whether or not such  rights,  options or warrants  are  immediately
exercisable.

                  (f)   Reservation  of  Shares;   Transfer   Taxes,   Etc.  The
Corporation shall at all times reserve and keep available, out of its authorized
and unissued  shares of Common  Stock,  solely for the purpose of effecting  the
conversion of the Series D Preferred Stock,  such number of shares of its Common
Stock free of preemptive  rights as shall be sufficient to effect the conversion
of all  shares  of  Series  D  Preferred  Stock  from  time to time  outstanding
(including,  without limitation, shares of Common Stock issuable upon conversion
of the Series D Preferred  Stock in the case of a Reset Event.  The  Corporation
shall use its best efforts from time to time, in accordance with the laws of the
State of Delaware to increase the authorized number of shares of Common Stock if
at any time the number of shares of authorized,  unissued and unreserved  Common
Stock  shall  not  be   sufficient   to  permit  the   conversion   of  all  the
then-outstanding shares of Series D Preferred Stock.

                  The  Corporation  shall pay any and all  issue or other  taxes
that may be  payable in  respect  of any issue or  delivery  of shares of Common
Stock on conversion of the Series D Preferred Stock. The Corporation  shall not,
however,  be  required  to pay any tax which may be  payable  in  respect of any
transfer  involved in the issue or delivery of Common Stock (or other securities
or assets)  in a name other than that in which the shares of Series D  Preferred
Stock so converted were registered.  and no such issue or delivery shall be made
unless and until the person  requesting  such issue has paid to the  Corporation
the  amount  of  such  tax  or  has  established,  to  the  satisfaction  of the
Corporation, that such tax has been paid.

                  (g)      Prior Notice of Certain Events.  In case:

                           (i)  the Corporation shall declare any dividend (or 
                  any other distribution); or

                           (ii) the Corporation  shall authorize the granting to
                  the holders of Common Stock of rights or warrants to subscribe
                  for or  purchase  any  shares  of stock of any class or of any
                  other rights or warrants; or

                           (iii) of any  reclassification of Common Stock (other
                  than a subdivision or combination  of the  outstanding  Common
                  Stock,  or a change in par value,  or from par value to no par
                  value, or from no par value to par value); or


                                      -17-



<PAGE>



                           (iv)  of  any  consolidation  or  merger  (including,
                  without  limitation,   a  Merger  Transaction)  to  which  the
                  Corporation   is  a  party  and  for  which  approval  of  any
                  stockholders of the Corporation  shall be required,  or of the
                  sale or transfer of all or substantially  all of the assets of
                  the  Corporation or of any compulsory  share exchange  whereby
                  the Common Stock is converted into other  securities,  cash or
                  other property; or

                           (v)   of the voluntary or involuntary dissolution, 
                  liquidation  or winding up of the  Corporation  (including,  
                  without limitation, a Liquidation Event);

then the  Corporation  shall cause to be filed with the  transfer  agent for the
Series D  Preferred  Stock,  and  shall  cause to be  mailed  to the  Registered
Holders,  at their last  addresses as they shall appear upon the stock  transfer
books of the Corporation,  at least 20 days prior to the applicable  record date
hereinafter  specified, a notice stating (x) the date on which a record (if any)
is to be taken for the  purpose of such  dividend.  distribution  or granting of
rights or warrants or, if a record is not to be taken,  the date as of which the
holders of Common Stock of record to be entitled to such dividend, distribution,
rights  or  warrants  are  to be  determined  and a  description  of  the  cash,
securities or other  property to be received by such holders upon such dividend,
distribution  or  granting  of rights or  warrants or (y) the date on which such
reclassification,   consolidation,   merger,  sale,  transfer,  share  exchange,
dissolution, liquidation or winding up or other Liquidation Event is expected to
become  effective,  the date as of which it is expected  that  holders of Common
Stock of record  shall be entitled to exchange  their shares of Common Stock for
securities  or other  property  deliverable  upon  such  exchange,  dissolution,
liquidation  or winding  up or other  Liquidation  Event and the  consideration,
including securities or other property, to be received by such holders upon such
exchange;  provided,  however, that no failure to mail such notice or any defect
therein or in the mailing  thereof  shall affect the  validity of the  corporate
action required to be specified in such notice.

                  (h) Other Changes in Conversion  Rate.  The  Corporation  from
time to time may  increase the  Conversion  Rate by any amount for any period of
time if the period is at least 20 days and if the increase is irrevocable during
the period. Whenever the Conversion Rate is so increased,  the Corporation shall
mail to the Registered  Holders a notice of the increase at least 15 days before
the date the increased Conversion Rate takes effect, and such notice shall state
the increased Conversion Rate and the period it will be in effect.

                  The  Corporation  may make such  increases  in the  Conversion
Rate,  in addition to those  required or allowed by this  Section 4, as shall be
determined by it, as evidenced by a resolution of the Board of Directors,  to be
advisable  in order to avoid or  diminish  any  income  tax to holders of Common
Stock resulting from any dividend or distribution of stock or issuance of rights
or warrants to purchase or subscribe for stock or from any event treated as such
for income tax purposes.


                                      -18-



<PAGE>



                  Notwithstanding  anything to the contrary  herein,  in no case
shall the  Conversion  Price be adjusted to an amount less than $.001 per share,
the  current  par value of the Common  Stock  into which the Series D  Preferred
Stock is convertible.

                  (i)   Ambiguities/Errors.   The  Board  of  Directors  of  the
Corporation  shall have the power to resolve any  ambiguity or correct any error
in the  provisions  relating  to the  convertibility  of the Series D  Preferred
Stock, and its actions in so doing shall be final and conclusive.

                  5.  Mandatory  Conversion.  At any time on or after  the Reset
Date, the  Corporation at its option,  may cause the Series D Preferred Stock to
be  converted  in whole or in part,  on a pro rata  basis,  into  fully paid and
nonassessable  shares of Common Stock at the then effective  Conversion  Rate if
the Closing Bid Price (or, if the price  referenced in the definition of Closing
Bid Price cannot be determined, the Fair Market Value) of the Common Stock shall
have  exceeded  300% of the then  applicable  Conversion  Price  for at least 20
trading days in any 30 consecutive trading day period ending three days prior to
the date of notice of  conversion.  Any  shares of Series D  Preferred  Stock so
converted shall be treated as having been  surrendered by the holder thereof for
conversion  pursuant  to  Section  4 on the  date of such  mandatory  conversion
(unless previously converted at the option of the holder).

                  No greater than 60 nor fewer than 20 days prior to the date of
any such  mandatory  conversion,  notice by first class mail,  postage  prepaid,
shall be given to the  holders of record of the Series D  Preferred  Stock to be
converted,  addressed  to such  holders at their last  addresses as shown on the
stock transfer books of the Corporation. Each such notice shall specify the date
fixed for  conversion,  the place or places for  surrender of shares of Series D
Preferred Stock, and the then effective Conversion Rate pursuant to Section 4.

                  Any  notice  which  is  mailed  as  herein  provided  shall be
conclusively  presumed  to have been duly given by the  Corporation  on the date
deposited in the mail, whether or not the holder of the Series D Preferred Stock
receives such notice;  and failure  properly to give such notice by mail, or any
defect in such notice,  to the holders of the shares to be  converted  shall not
affect the validity of the proceedings for the conversion of any other shares of
Series D Preferred Stock. On or after the date fixed for conversion as stated in
such notice,  each holder of shares called to be converted  shall  surrender the
certificate evidencing such shares to the Corporation at the place designated in
such notice for conversion. Notwithstanding that the certificates evidencing any
shares  properly  called for  conversion  shall not have been  surrendered,  the
shares  shall no longer be deemed  outstanding  and all rights  whatsoever  with
respect to the shares so called for conversion  (except the right of the holders
to convert such shares upon  surrender  of their  certificates  therefor)  shall
terminate.


                                      -19-



<PAGE>



                  6.       Voting Rights.

                  (a)  General.  Except as  otherwise  provided  herein,  in the
Certificate of Incorporation or the By-laws of the Corporation or as required by
applicable law, the holders of shares of Series D Preferred  Stock,  the holders
of shares of Common Stock and the holders of any other class or series of shares
entitled to vote with the Common  Stock shall vote  together as one class on all
matters  submitted to a vote of  stockholders  of the  Corporation.  In any such
vote, each share of Series D Preferred Stock shall entitle the holder thereof to
cast the  number of votes  equal to the number of votes  which  could be cast in
such vote by a holder of the  Common  Stock  into  which  such share of Series D
Preferred Stock is convertible on the record date for such vote, or if no record
date has been established,  on the date such vote is taken. Any shares of Series
D  Preferred  Stock  held by the  Corporation  or any entity  controlled  by the
Corporation  shall not have voting rights  hereunder and shall not be counted in
determining the presence of a quorum.

                  (b) Class Voting Rights.  In addition to any vote specified in
Section 6(a), so long as at least 50% of the shares of Series D Preferred  Stock
(including  those shares of Series D Preferred Stock issued or issuable upon the
conversion of the Bridge Notes, the exercise of the warrants issued to Paramount
Capital,  Inc., the placement agent in connection with the offer and sale of the
Series D Preferred  Stock or any other  warrants or options for the  purchase of
Series D Preferred  Stock)  shall be  outstanding,  the  Corporation  shall not,
without  the  affirmative  vote or consent of the holders of at least 50% of all
outstanding  Series D Preferred Stock,  voting separately as a class, (i) amend,
alter or repeal any provision of the Certificate of  Incorporation or the Bylaws
of the Corporation so as adversely to affect the relative  rights,  preferences,
qualifications,  limitations or  restrictions  of the Series D Preferred  Stock,
(ii) approve the  alteration or change to the rights,  preferences or privileges
of the Series D Preferred Stock,  (iii) incur or voluntarily  repay prior to the
maturity  thereof any  indebtedness  (other than the Bridge  Notes) in excess of
$2,000,000 or (iv) authorize or issue, or increase the authorized amount of, any
equity  security  ranking prior to, or on a parity with,  the Series D Preferred
Stock (other than additional Series D Preferred Stock approved in writing by the
Placement  Agent) (A) upon a Liquidation  Event, (B) with respect to the payment
of any dividends or  distributions  or (C) with respect to voting rights (except
for class voting rights required by law).

                  7.  Outstanding  Shares.  For purposes of this  Certificate of
Designation,  a share of Series D Preferred Stock, when issued,  shall be deemed
outstanding  except  (i) from the date,  or the deemed  date,  of  surrender  of
certificates evidencing shares of Series D Preferred Stock, all shares of Series
D  Preferred  Stock  converted  into  Common  Stock  and  (ii)  from the date of
registration of transfer,  all shares of Series D Preferred Stock held of record
by the Corporation or any subsidiary of the Corporation.


                                      -20-



<PAGE>



                  8.  Status of  Acquired  Shares.  Shares of Series D Preferred
Stock received upon  conversion  pursuant to Section 4 or Section 5 or otherwise
acquired by the  Corporation  will be restored to the status of  authorized  but
unissued shares of Preferred  Stock,  without  designation as to class,  and may
thereafter be issued, but not as shares of Series D Preferred Stock.

                  9.   Preemptive Rights.  The Series D Preferred Stock is not 
entitled to any preemptive or  subscription  rights in respect of any securities
of the Corporation.

                  10.  Severability  of  Provisions.   Whenever  possible,  each
provision  hereof shall be  interpreted in a manner as to be effective and valid
under applicable law, but if any provision hereof is held to be prohibited by or
invalid under  applicable law, such provision  shall be ineffective  only to the
extent of such  prohibition or  invalidity,  without  invalidating  or otherwise
adversely  affecting the remaining  provisions  hereof.  If a court of competent
jurisdiction  should  determine  that a  provision  hereof  would  be  valid  or
enforceable  if a period of time were  extended  or  shortened  or a  particular
percentage were increased or decreased, then such court may make such changes as
shall be necessary to render the provision in question effective and valid under
applicable law.

                  11. No  Amendment or  Impairment.  The  Corporation  shall not
amend its  Certificate of  Incorporation  or participate in any  reorganization,
transfer  of  assets,  consolidation,  merger,  dissolution,  issue  or  sale of
securities or any other voluntary action, for the purpose of avoiding or seeking
to avoid the  observance  or  performance  of any of the terms to be observed or
performed  hereunder  by the  Corporation,  but will at all times in good  faith
assist  in  carrying  out all such  action  as may be  reasonably  necessary  or
appropriate  in order to  protect  the  rights of the  holders  of the  Series D
Preferred Stock against impairment.

                  12. Redemption  Parity.  (a) If the Corporation is required to
repurchase,  redeem or  otherwise  acquire  (collectively,  "Redeem")  shares of
Series A Preferred Stock representing more than 5% of the aggregate stated value
of the Series A Preferred  Stock,  then the  Corporation  shall,  subject to its
prior compliance with Article IV of the Certificate of  Incorporation,  offer to
Redeem the shares of Series D  Preferred  Stock,  on a pari passu basis with the
Series A Preferred Stock based on the relative  liquidation  preferences of each
such series of  Preferred  Stock.  The  Corporation  shall  Redeem the shares of
Series D  Preferred  Stock with the same type of  consideration  that is paid to
Redeem the Series A Preferred Stock, and the Corporation shall Redeem the shares
of Series D Preferred Stock in the same manner,  on the same schedule,  and upon
the same notice  (the  "Company  Notice"),  as it Redeems the Series A Preferred
Stock.

                  (b) If the Corporation  Redeems any Series D Preferred  Stock,
the  redemption  price shall be $140.00  per share of Series D Preferred  Stock,
subject to appropriate  adjustment for stock splits,  combinations  and the like
(the "Redemption Price").


                                      -21-



<PAGE>



                  (c) If the Corporation  Redeems any Series D Preferred  Stock,
the Registered  Holders shall be given the opportunity to elect to convert their
shares of Series D Preferred  Stock at the then applicable  Conversion  Price in
lieu of having such shares  Redeemed.  If the  Corporation  uses Common Stock to
Redeem any Series D Preferred  Stock,  then such Common  Stock will be valued at
its Market Price.

                  (d) The  Corporation's  obligation to provide moneys to Redeem
any Series D  Preferred  Stock  shall be deemed  fulfilled  if, on or before the
redemption  date,  the  Corporation  shall  deposit with a bank or trust company
having an office or agency in the Borough of  Manhattan,  City of New York,  and
having a capital and surplus of at least  $50,000,000,  the principal  amount of
funds necessary to so Redeem, in trust for the account of the Registered Holders
of the  shares to be  Redeemed  (and so as to be and  continue  to be  available
therefor),  with  irrevocable  instructions  and authority to such bank or trust
company  that such funds be  applied to Redeem the shares of Series D  Preferred
Stock so called to be Redeemed. Any interest accrued on such funds shall be paid
to the  Corporation  from time to time.  Any funds so deposited and unclaimed at
the end of three years from such  redemption date shall be released or repaid to
the Corporation, after which, subject to any applicable laws relating to escheat
or  unclaimed  property,  any  Registered  Holders  of such  shares  of Series D
Preferred  Stock so called to be Redeemed shall look only to the Corporation for
payment of the Redemption Price.

                  (e) Upon  surrender  of the  certificates  for any  shares  of
Series D Preferred Stock to be Redeemed by the Corporation (properly endorsed or
assigned  for  transfer,  if the Board of  Directors  shall so  require  and the
Company Notice shall so state), such shares shall be Redeemed by the Corporation
at the Redemption Price.







                            [Signature page follows]

                                      -22-



<PAGE>




                  IN  WITNESS  WHEREOF,  David  R.  Walner,   Secretary  of  the
Corporation,  acting  for  and  on  behalf  of  the  Corporation,  has  hereunto
subscribed his name this 29th day of May, 1997.





                                                     GENTA INCORPORATED



                                                     By:
                                                        ------------------------
                                                     Name:  David. R. Walner
                                                     Title:  Secretary


                                      -23-


<PAGE>


                                   Exhibit Q

                 AMENDED AND RESTATED AMENDMENT AGREEMENT

          The undersigned,  intending legally to be bound, hereby agree that the
Amendment  Agreement between the undersigned,  dated May 20, 1997, as previously
amended, and all the exhibits thereto,  shall be amended and restated to read in
their entirety as follows and otherwise agree as follows:

          1. The  Certificate  of  Designations  for the  Series  D  Convertible
Preferred  Stock  of  Genta  Incorporated  (the  "Company")  shall  be  amended,
effective as of May 20, 1997, to read as set forth in Exhibit A hereto.

          2. The Senior Secured  Convertible Bridge Notes issued on February 13,
1997 shall be amended,  effective as of the date hereof, to read as set forth in
Exhibits B-1 and B-2 hereto.

          3. The Company's  Class A and Class B Bridge Warrants for the Purchase
of Shares of Common Stock (numbers CA-1,  CA-2,  CB-1 and CB-2) (the "Old Bridge
Warrants") shall be exchanged, effective as of the date hereof, for New Warrants
(the "New Bridge Warrants") which,  notwithstanding  the provisions of Section 9
of the Bridge  Warrants,  shall read in their  entirety as set forth in Exhibits
CA-1,  CA-2,  CB-1  and  CB-2  hereto,  and the Old  Bridge  Warrants  shall  be
cancelled.

          4. If Aries Domestic Fund, L.P. and The Aries Trust (collectively, the
"Aries Funds") purchase  securities in the Company's private placement commenced
on May 20,  1997,  then  the  Aries  Funds  will  not  vote or  dispose  of such
securities or convert any such securities  into, or exercise any such securities
for, any shares of Common Stock of the Company, for a period of 90 days from the
date of such purchase.

          5.  Except as amended  hereby and except for the  exchange  of the New
Bridge Warrants for Old Bridge Warrants, the instruments and securities referred
to herein shall continue in full force and effect.

          6. This agreement may be executed in two or more counterparts, each of
which shall be deemed an original,  but all of which shall  together  constitute
one and the same instrument.

<PAGE>


          IN WITNESS WHEREOF,  the parties hereto have executed this Amended and
Restated Amendment Agreement as of June 23, 1997.


                         GENTA INCORPORATED


                         -------------------------------------
                         By:



                         THE ARIES TRUST, A CAYMAN ISLAND TRUST



                         By: its Investment Manager, PARAMOUNT
                         CAPITAL ASSET MANAGEMENT, INC.


                         By: /s/ Lindsay A. Rosenwald
                         ----------------------------
                             Name:  Lindsay A. Rosenwald, M.D.
                             Title: President



                         THE ARIES DOMESTIC FUND, L.P.



                         By: its General Partner, PARAMOUNT
                         CAPITAL ASSET MANAGEMENT, INC.


                         By: /s/ Lindsay A. Rosenwald
                         ----------------------------
                             Name:  Lindsay A. Rosenwald, M.D.
                             Title: President



<PAGE>

                                    EXHIBIT R

THIS NOTE IS NOT  TRANSFERABLE  WITHOUT  THE  EXPRESS  WRITTEN  CONSENT OF GENTA
INCORPORATED,  (THE "COMPANY"). THE SECURITIES REPRESENTED BY THIS NOTE HAVE NOT
BEEN  REGISTERED  UNDER  THE  SECURITIES  ACT OF  1933 OR ANY  APPLICABLE  STATE
SECURITIES LAWS, AND MAY NOT BE SOLD,  OFFERED FOR SALE, PLEDGED OR HYPOTHECATED
OR OTHERWISE  TRANSFERRED IN THE ABSENCE OF A  REGISTRATION  STATEMENT IN EFFECT
WITH RESPECT TO THE  SECURITIES  UNDER SUCH ACT OR AN EXEMPTION  THEREFROM.  ANY
SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE STATE SECURITIES LAWS.


                               GENTA INCORPORATED

                                                                         No. B-1
           AMENDED AND RESTATED SENIOR SECURED CONVERTIBLE BRIDGE NOTE

$1,050,000                                                 New York, New York
                                                           January 28, 1997, as
                                                           amended and restated
                                                           on June 23, 1997

                  Genta Incorporated,  a Delaware corporation,  (the "Company"),
for value  received,  hereby promises to pay to THE ARIES DOMESTIC FUND, LP (the
"Holder"),  or  registered  assigns,  the  principal  sum of ONE  MILLION  FIFTY
THOUSAND DOLLARS ($1,050,000),  with interest from the date of original issuance
of this Senior Secured  Convertible  Bridge Note on the unpaid principal balance
at a rate  equal to  twelve  percent  (12%) per  annum,  on the  earlier  of (a)
December  31,  1997,  (b)  September  30,  1997 if on or prior to such  date the
Company has not received gross proceeds of at least $2,000,000 in respect of its
offering of Premium Preferred Units which was commenced in May, 1997 and (c) the
date of any decision, order or other determination adverse to the Company or any
of its  directors  by any  court  or  other  tribunal  in any  lawsuit  or other
proceeding  against  the  Company  and/or  any  of its  directors  by any of the
Company's preferred  stockholders,  including,  without limitation,  any adverse
result or other  determination  in  connection  with an  appeal of the  decision
rendered by the Delaware  Court of Chancery in May,  1997 in respect of the suit
described in Item 3 of the Company's  Form 10-K for the year ended  December 31,
1996 (such earliest date,  the "Maturity  Date").  Payment shall be made at such
place  as  designated  by the  Holder  upon  surrender  of this  Senior  Secured
Convertible  Bridge  Note,  and shall be in such coin or  currency of the United
States  of  America  as at the time of  payment  shall be legal  tender  for the
payment of public and private debts.  Interest shall be computed on the basis of
a 360-day year of twelve 30-day months.  This Senior Secured  Convertible Bridge
Note  is one  of a duly  authorized  issue  of  Genta  Incorporated  12%  Senior
Convertible  Bridge  Notes  in  an  aggregate  principal  amount  of  $3,000,000
(individually a "Note"




<PAGE>



and  collectively  the "Notes") issued  pursuant to a Note and Warrant  Purchase
Agreement  dated  January  28,  1997  between  the  Company  and the Holder (the
"Purchase  Agreement").  The Senior  Secured  Convertible  Bridge Notes shall be
senior to all other  indebtedness of the Company ("Other  Indebtedness") and all
Other Indebtedness shall be subordinated to the Senior Bridge Notes. These Notes
are secured  pursuant to the Security  Agreement dated as of January 28, 1997 by
and between the Company, Paramount Capital, Inc. and the Purchasers.

SECTION 1.          PREPAYMENT.

                  This Note (including interest accrued on the principal hereof)
may be prepaid by the Company,  at any time without penalty or premium  provided
that the  Company  shall  provide the holders of the Notes with at least 30 days
prior written notice of prepayment, and prior to such prepayment, the holders of
the Notes shall have the  opportunity  to  exercise  their  optional  conversion
rights pursuant to Section 2 hereof.

SECTION 2.          OPTIONAL CONVERSION

                  (a) Right of  Conversion.  (i)  Immediately,  or,  (ii) if the
rules of the Nasdaq National Market or any other law or regulation,  require the
approval  of the  shareholders  of the Company to permit  convertibility  of the
Notes, then upon the receipt of such approvals,  the Notes shall be convertible,
in whole or in part, at the option of the holder  thereof and upon notice to the
Corporation as set forth in paragraph  2(b) below,  into the number of shares of
Series D Preferred  Stock of the Company (the  "Preferred  Stock")  equal to the
Conversion  Amount  divided by the then  current  Conversion  Price (as  defined
below). The Conversion Amount shall be the Liquidation Amount, or in the case of
a partial conversion, such lesser amount as designated by the converting holder.
The Liquidation Amount shall be the aggregate  principal value of the Notes held
by such Holder plus any accrued and unpaid interest.  The Conversion Price shall
initially be $50.00,  subject to adjustment as provided  below,  representing an
initial conversion rate (subject to adjustment) of 200 shares of Preferred Stock
per $10,000 of  Conversion  Amount.  Notwithstanding  anything  to the  contrary
contained in this Note,  no right of  conversion  shall exist if and only to the
extent that such  conversion  would result in the  occurrence of a  "Fundamental
Change"  under  Article  IV  of  the  Corporation's   Restated   Certificate  of
Incorporation.

                  (b)  Conversion  Procedures.  Any holder of Notes  desiring to
convert such Notes into Preferred Stock shall surrender the Notes at the offices
of the Company,  which Notes shall be accompanied by irrevocable  written notice
to the  Corporation  that  the  holder  elects  so to  convert  such  Notes  and
specifying  the  name  or  names  (with  address)  in  which  a  certificate  or
certificates  evidencing  shares  of  Preferred  Stock  are  to be  issued.  The
Corporation  will make a  notation  of the date that a notice of  conversion  is
received,  which  date shall be deemed to be the date of  receipt  for  purposes
hereof.

                  The  Corporation  shall deliver to the holder  converting  the
Notes, or to the nominee or nominees of such person, certificates evidencing the
number of full shares of



                                        2

<PAGE>



Preferred  Stock to which such person shall be entitled as  aforesaid,  together
with a cash  adjustment  of any  fraction  of a share as  hereinafter  provided.
Subject to the following provisions of this paragraph,  such conversion shall be
deemed to have been made as of the date of such  surrender  of the Notes and the
person or persons  entitled  to receive the  Preferred  Stock  deliverable  upon
conversion  of such Notes shall be treated for all purposes as the record holder
or holders of such Preferred  Stock on such date;  provided,  however,  that the
Corporation  shall not be required to convert any Notes while the stock transfer
books of the Corporation are closed for any purpose,  but the surrender of Notes
for  conversion  during any period  while such books are so closed  shall become
effective for conversion  immediately upon the reopening of such books as if the
surrender had been made on the date of such reopening,  and the conversion shall
be at the conversion rate in effect on such date.

                  All  notices of  conversion  shall be  irrevocable;  provided,
however,  that if the  Corporation  has  sent  notice  of an event  pursuant  to
paragraph  2(e) hereof,  a holder of Notes may, at its election,  provide in its
notice of conversion  that the conversion of its Notes shall be contingent  upon
the occurrence of the record date or  effectiveness  of such event (as specified
by such  holder),  provided  that such notice of  conversion  is received by the
Corporation prior to such record date or effective date, as the case may be.

                  (c) Protection From Dilution. (i) If, at any time or from time
to time after the date of this Note,  the Company  shall issue or  distribute to
the holders of shares of Preferred Stock evidence of its indebtedness, any other
securities  of the Company or any cash,  property or other  assets  (excluding a
subdivision,  combination  or  reclassification,  or  dividend  or  distribution
payable  solely to  holders of  Preferred  Stock in shares of  Preferred  Stock,
referred to in Subsection  (c)(ii),  and also  excluding  cash dividends or cash
distributions  paid out of net profits  legally  available  therefor in the full
amount  thereof  (any such  non-excluded  event being  herein  called a "SPECIAL
DIVIDEND"), the Conversion Price shall be adjusted by multiplying the Conversion
Price then in effect by a  fraction,  the  numerator  of which shall be the then
Current  Market Price Per Share of Preferred  Stock in effect on the record date
of such issuance or  distribution  less the fair market value (as  determined in
good faith by the Company's Board of Directors) of the evidence of indebtedness,
cash,  securities  or property,  or other assets issued or  distributed  in such
Special Dividend  applicable to one share of Preferred Stock and the denominator
of which shall be the then Current Market Price Per Share of Preferred  Stock in
effect on the record date of such issuance or  distribution.  An adjustment made
pursuant to this Subsection 2(a) shall become  effective  immediately  after the
record date of any such Special  Dividend.  The then  "CURRENT  MARKET PRICE PER
SHARE OF PREFERRED  STOCK" shall equal the then Current Market Price  multiplied
by the then effective  "Conversion Rate" (as defined and used in the Certificate
of Designation for the Preferred Stock).

The then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed, or if not listed or admitted to trading



                                        3

<PAGE>



on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined in good faith by the Board of Directors.

                  (ii) In case the Company shall hereafter (i) pay a dividend or
make a  distribution  on its capital  stock in shares of Preferred  Stock,  (ii)
subdivide its  outstanding  shares of Preferred  Stock into a greater  number of
shares,  (iii) combine its outstanding  shares of Preferred Stock into a smaller
number of shares or (iv) issue by  reclassification  of its Preferred  Stock any
shares of capital stock of the Company (other than the Conversion  Shares),  the
Conversion  Price shall be  proportionately  adjusted so that the Notes shall be
convertible  into a number and kind of  securities  which the holders would have
been  entitled  to  receive  after any such event had they  converted  the Notes
immediately  prior  thereto.  An  adjustment  made  pursuant to this  Subsection
2(c)(ii) shall become effective immediately after the record date in the case of
a dividend or  distribution  and shall become  effective  immediately  after the
effective date in the case of a subdivision, combination or reclassification.

                  (iii) Except as provided in Subsections (c)(i) and (c)(iv), in
case  the  Company  shall  hereafter  issue  or sell any  Preferred  Stock,  any
securities  convertible into Preferred Stock, any rights, options or warrants to
purchase Preferred Stock or any securities  convertible into Preferred Stock, in
each case for a price per share or  entitling  the  holders  thereof to purchase
Preferred  Stock at a price  per share  (determined  by  dividing  (i) the total
amount,  if any,  received or receivable by the Company in  consideration of the
issuance  or sale of such  securities  plus  the  total  consideration,  if any,
payable  to  the  Company  upon  exercise  or  conversion  thereof  (the  "TOTAL
CONSIDERATION")  by (ii) the  number of  additional  shares of  Preferred  Stock
issuable  upon exercise or  conversion  of such  securities)  which is less than
either the then Current  Market Price Per Share of Preferred  Stock in effect on
the date of such issuance or sale or the Conversion  Price, the Conversion Price
shall be adjusted as of the date of such  issuance  or sale by  multiplying  the
Conversion  Price then in effect by a fraction,  the numerator of which shall be
(x) the sum of (A) the number of shares of Preferred  Stock  outstanding  on the
record date of such issuance or sale plus (B) the Total Consideration divided by
the Current Market Price Per Share of Preferred Stock or the current  Conversion
Price,  whichever  is  greater,  and the  denominator  of which shall be (y) the
number of shares of  Preferred  Stock  outstanding  on the  record  date of such
issuance or sale plus the maximum number of additional shares of Preferred Stock
issued, sold or issuable upon exercise or conversion of such securities.

                  (iv)   In   case   of   any    capital    reorganization    or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or substantially as a entirety, or in the
case of any statutory exchange of securities with another corporation (including
any exchange effected in



                                        4

<PAGE>



connection with a merger of a third corporation into the Company), the Holder of
this Note shall have the right  thereafter to receive on the  conversion of this
Note the kind and amount of securities,  cash or other property which the Holder
would  have  owned or have been  entitled  to  receive  immediately  after  such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or  conveyance  had  this  Note  been  converted  immediately  prior to the
effective date of such reorganization, reclassification,  consolidation, merger,
statutory  exchange,  sale or  conveyance  and in any such case,  if  necessary,
appropriate  adjustment  shall be made in the  application of the provisions set
forth in this Section 2 with respect to the rights and  interests  thereafter of
the Holder of this Note to the end that the provisions set forth in this Section
2  shall  thereafter  correspondingly  be  made  applicable,  as  nearly  as may
reasonably  be,  in  relation  to any  shares  of stock or other  securities  or
property  thereafter  deliverable  on the  Note.  The above  provisions  of this
Subsection   (c)(iv)  shall  similarly  apply  to  successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The  Company  shall  require  the issuer of any shares of stock or
other securities or property thereafter deliverable on the exercise of this Note
to be  responsible  for all of the  agreements  and  obligations  of the Company
hereunder. Notice of any such reorganization,  reclassification,  consolidation,
merger,  statutory  exchange,  sale  or  conveyance  and of said  provisions  so
proposed  to be made,  shall be mailed to the Holders of the Notes not less than
30 days prior to such event. A sale of all or substantially all of the assets of
the Company for a  consideration  consisting  primarily of  securities  shall be
deemed a consolidation or merger for the foregoing purposes.

                  (v) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 2 are not strictly  applicable  but as to which the
failure to make any adjustment  would not fairly  protect the conversion  rights
represented by this Note in accordance with the essential  intent and principles
hereof  then,  in each such case,  the  Holders  of Notes may  appoint a firm of
independent  public  accountants  of  recognized  national  standing  reasonably
acceptable to the Company,  which shall give their opinion as to the adjustment,
if  any,  on a  basis  consistent  with  the  essential  intent  and  principles
established herein, necessary to preserve the conversion rights. Upon receipt of
such  opinion,  the Company will  promptly  mail a copy thereof to the Holder of
this  Note  and  shall  make the  adjustments  described  therein.  The fees and
expenses of such independent public accountants shall be borne by the Company.

                  (vi) For purposes of the anti-dilution protection contained in
this  Section  (c),  at all times  following  the  conversion  of all  shares of
Preferred  Stock into shares of Common Stock,  the term Preferred Stock shall be
read  to  be  Common  Stock,  context  permitting,  so  that  the  anti-dilution
provisions  will continue to protect the conversion  rights  represented by this
Note after the  conversion of all the  Preferred  Stock into the Common Stock in
accordance with the essential  intent and principles of this Section 3 (it being
understood that prior to such conversion,  the  anti-dilution  provisions of the
Preferred Stock  underlying this Note shall be applicable to any dilutive events
with  respect to the Common  Stock and protect  the Holder from  dilution of the
Common Stock).




                                        5

<PAGE>



                  (d)   Reservation  of  Shares;   Transfer   Taxes;   Etc.  The
Corporation shall at all times reserve and keep available, out of its authorized
and unissued shares of Preferred Stock,  solely for the purpose of effecting the
conversion of the Notes,  such number of shares of its  Preferred  Stock free of
preemptive  rights as shall be sufficient to effect the  conversion of all Notes
from time to time  outstanding.  The Corporation shall use its best efforts from
time to time, in accordance with the laws of the State of Delaware,  to increase
the authorized  number of shares of Preferred Stock if at any time the number of
shares of Preferred Stock not outstanding  shall not be sufficient to permit the
conversion of all the then-outstanding Notes.

                  The  Corporation  shall pay any and all  issue or other  taxes
that may be payable in respect of any issue or delivery  of shares of  Preferred
Stock on  conversion  of the  Notes.  The  Corporation  shall not,  however,  be
required to pay any tax which may be payable in respect of any transfer involved
in the issue or delivery of Preferred Stock (or other securities or assets) in a
name other than that in which the Notes so  converted  were  registered,  and no
such issue or delivery shall be made unless and until the person requesting such
issue has paid to the Corporation the amount of such tax or has established,  to
the satisfaction of the Corporation, that such tax has been paid.

                  (e)      Prior Notice of Certain Events.  In case:

                    (i)    the Corporation shall declare any dividend (or any 
         other distribution); or

                    (ii) the  Corporation  shall  authorize  the granting to the
         holders of Preferred  Stock of rights or warrants to  subscribe  for or
         purchase  any  shares of stock of any  class or of any other  rights or
         warrants; or

                    (iii) of any reclassification of Preferred Stock (other than
         a subdivision or combination of the outstanding  Preferred  Stock, or a
         change in par value,  or from par value to no par value, or from no par
         value to par value); or

                    (iv) of any consolidation or merger to which the Corporation
         is  a  party  and  for  which  approval  of  any  stockholders  of  the
         Corporation  shall be  required,  or of the sale or  transfer of all or
         substantially all of the assets of the Corporation or of any compulsory
         share  exchange  whereby the  Preferred  Stock is converted  into other
         securities, cash or other property; or

                    (v)    of the voluntary or involuntary dissolution, 
         liquidation or winding up of the Corporation;

then the Corporation  shall cause to be mailed to the holders of Notes, at their
last addresses as they shall appear upon the books of the Corporation,  at least
20 days prior to the  applicable  record date  hereinafter  specified,  a notice
stating  (x) the date on which a record (if any) is to be taken for the  purpose
of such dividend, distribution or granting of rights or warrants or, if a record
is not to be  taken,  the date as of which the  holders  of  Preferred  Stock of
record to be



                                        6

<PAGE>



entitled to such dividend, distribution, rights or warrants are to be determined
and a description  of the cash,  securities or other  property to be received by
such holders upon such dividend,  distribution or granting of rights or warrants
or (y) the date on which such  reclassification,  consolidation,  merger,  sale,
transfer,  share  exchange,  dissolution,  liquidation  or  winding  up or other
liquidation  event is expected to become  effective,  the date as of which it is
expected that holders of Preferred Stock of record shall be entitled to exchange
their shares of Preferred  Stock for  securities or other  property  deliverable
upon such exchange, dissolution,  liquidation or winding up or other liquidation
event and the  consideration,  including  securities  or other  property,  to be
received by such holders upon such exchange;  provided, however, that no failure
to mail such notice or any defect therein or in the mailing thereof shall affect
the validity of the corporate action required to be specified in such notice.

                  (f) Other Changes in Conversion  Rate.  The  Corporation  from
time to time may  increase the  Conversion  Rate by any amount for any period of
time if the period is at least 20 days and if the increase is irrevocable during
the period. Whenever the Conversion Rate is so increased,  the Corporation shall
mail to  holders  of record of Notes a notice of the  increase  at least 15 days
before the date the  increased  Conversion  Rate takes  effect,  and such notice
shall state the increased Conversion Rate and the period it will be in effect.

                  The  Corporation  may make such  increases  in the  Conversion
Rate, in addition to those  required or allowed by this paragraph 4, as shall be
determined by it, as evidenced by a resolution of the Board of Directors,  to be
advisable  in order to avoid or  diminish  any  income  tax to holders of Common
Stock resulting from any dividend or distribution of stock or issuance of rights
or warrants to purchase or subscribe for stock or from any event treated as such
for income tax purposes.

SECTION 3.          DEFAULT CONVERSION.

                  (a) If this Note and all accrued  interest shall not have been
paid in full on or before the Maturity  Date or upon the  occurrence of an Event
of Default  (as  defined in Section 7 hereof),  the Holder  shall have the right
(the "Default  Conversion  Right"),  in addition to any other available remedies
set forth in  Section  8 hereof or at law or in  equity,  to  convert  up to the
lesser of (i) the then outstanding  principal amount of this Note or (ii) 10% of
the original  principal amount of this Note, into the number of shares of Common
Stock of the Company  ("Common  Stock"),  equal to the amount  converted  by the
Noteholder upon such Event of Default (the "Default  Conversion Amount") divided
by $.001 (the "Default  Conversion Price").  Upon conversion,  the Company shall
pay all accrued and unpaid interest on the Default Conversion Amount.

                  (b) To exercise the Default  Conversion  Right, the Holder, on
or before the 60th day after the Maturity  Date,  but before  payment in full of
the then  outstanding  principal and interest under this Note,  shall deliver to
the Company, at its office at as set forth in section 11, or at such other place
as is designated in writing by the Company,  a notice (the "Conversion  Notice")
stating that the Holder is exercising the Default Conversion Right, the Default



                                        7

<PAGE>



Conversion  Amount  and the  name or  names  in  which  the  Holder  wishes  the
certificates for shares of Common Stock to be issued.

                  (c) To the extent  permitted by applicable  law, upon exercise
of the Default  Conversion Right, the Holder shall be deemed to be the holder of
record  of  the  shares  of  Common  Stock  issuable  upon  such  exercise  (the
"Conversion  Shares"),  notwithstanding  that the transfer  books of the Company
shall then be closed or certificates  representing  such Conversion Shares shall
not then have been actually  delivered to the Holder. As soon as practicable and
in any event  within  five (5) days after  exercise  of the  Default  Conversion
Right,  the  Company  shall  issue and  deliver to the Holder a  certificate  or
certificates  evidencing  the  Conversion  Shares  registered in the name of the
Holder or its  designee,  provided  that the Company may require the holder,  by
notice given to the Holder promptly after receipt of the Conversion Notice, as a
condition to the delivery of such certificate or  certificates,  to present this
Note to the Company for the  placement  hereon of a legend  indicating  that the
Default  Conversion  Right  has been  exercised  to the  extent  of the  Default
Conversion  Amount,  and  this  Note  (unless  thereby  paid in  full)  shall be
immediately returned to the Holder.

                  (d) The  issuance of any shares or other  securities  upon the
exercise of the Default  Conversion  Right,  and the delivery of certificates or
other instruments  representing  such shares or other securities,  shall be made
without  charge to the  Holder  for any tax or other  charge in  respect of such
issuance.  The Company shall not, however,  be required to pay any tax which may
be payable in respect of any transfer  involved in the issue and delivery of any
certificate in a name other than that of the Holder and the Company shall not be
required to issue or deliver any such certificate unless and until the person or
persons  requesting  the issue thereof shall have paid to the Company the amount
of such tax or shall have  established to the  satisfaction  of the Company that
such tax has been paid.

                  (e) The  Holder  shall not have,  solely  on  account  of such
status as a Holder of this Note,  any rights of a  stockholder  of the  Company,
either at law or in equity,  or any notice of meetings of stockholders or of any
other proceedings of the Company except as provided in this Note.

                  (f) The  Company  shall at all times  following  the  Issuance
Date,  reserve and keep available out of its  authorized and unissued  shares of
Common  Stock,  solely for the  purpose of  providing  for the  exercise  of the
Default  Conversion  Right, such number of shares of Common Stock as shall, from
time to time, be sufficient for the exercise of the Default  Conversion Right in
full.  The  Company  covenants  that all shares of Common  Stock  issuable  upon
exercise of the Default Conversion Right shall be validly issued, fully paid and
nonassessable.

                  (g) The  anti-dilution  protections  set forth in Section 2(c)
hereof shall apply as well to the Default Conversion Right and the adjustment of
the Default Conversion Price hereunder,  provided, however, that for purposes of
such application all appropriate  references to Preferred Stock shall be read as
references to Common Stock and all references to the  Conversion  Price shall be
read as references to the Default Conversion Price, so as to give the Default



                                        8

<PAGE>



Conversion  Rights,  as  nearly  as  practicable,  the  anti-dilution  and other
protections provided for in section 2(c) with respect to the Optional Conversion
Right.

SECTION 4.          FRACTIONAL SHARES.

                  (a) The Company  shall not be required to issue  fractions  of
shares of Common Stock or other  capital  stock of the Company upon the exercise
of the Optional and Default  Conversion  Right. If any fraction of a share would
be issuable  on any  exercise of the  Optional or Default  Conversion  Right (or
specified  portions  thereof),  the Company shall  purchase such fraction for an
amount in cash equal to the same  fraction of the  closing  price for the Common
Stock on the  trading  date  immediately  preceding  the date of exercise of the
Optional or Default Conversion Right.

SECTION 5.          AFFIRMATIVE COVENANTS OF THE COMPANY.

                  The  Company  covenants  and agrees  that until the payment in
full of this Note, the Company shall:

                  (a) Existence; Business.  (i) Preserve, renew and keep in 
full force and effect its legal  existence  and (ii)  obtain,  preserve,  renew,
extend and keep in full force and effect the licenses, permits,  authorizations,
patents, trademarks and trade names material to its business.

                  (b) Use of  Proceeds.  Use the  proceeds  of the Notes of this
issue  solely  as set  forth in  Section  7.7 of the Note and  Warrant  Purchase
Agreement between the Company and various  purchasers dated the date hereof (the
"Purchase Agreement")

                  (c) Reports.  Furnish to the Holder,  at the time furnished to
the  Company's  stockholders,  reports  furnished  generally  to  the  Company's
stockholders, and copies of Current Reports on Form 8-K.

                  (d) Notice of Events of Default.  Furnish to the Holder prompt
written notice of any Event of Default, specifying the nature and extent thereof
and corrective action, if any, proposed to be taken with respect thereto.

                  (e) Authorization of Stock Issuable Upon Conversion.  No later
than the Maturity Date,  authorize and reserve a sufficient number of its shares
for exercise of the Default Conversion Right.

SECTION 6.          NEGATIVE COVENANTS OF THE COMPANY.

                  The  Company  covenants  and agrees with the Holder that until
the payment in full of this Note, the Company shall not:




                                        9

<PAGE>



                  (a) Indebtedness. Incur, create, assume or permit to exist any
indebtedness except (i) indebtedness represented by the Notes, (ii) indebtedness
which by its terms is  subordinated  to the Notes in an amount less than $25,000
in the  aggregate  (iii)  indebtedness  in an amount  less than  fifty  thousand
dollars  ($50,000)  incurred  in the  ordinary  course  of  business,  and  (iv)
indebtedness  for borrowed  money  existing on the date hereof and  disclosed in
writing to the Holder on or prior to the date  hereof,  but not any  extensions,
renewals or replacements of such indebtedness;

                  (b) Liens.  Create,  incur, assume or permit to exist any lien
on any property or assets  (including  stock or other  securities of any person)
now owned or hereafter  acquired by the Company,  except (i) liens for taxes not
yet due or which are being contested by appropriate proceedings; (ii) carriers',
warehousemen's,  mechanic's,  materialmen's,  repairmen's  or other  like  liens
arising in the ordinary course of business and securing obligations that are not
due or which are being  contested;  or (iii) liens of attachments,  judgments or
awards against the Company (X) which could not reasonably be expected to have an
adverse material effect on the Company or (Y) with respect to which an appeal or
proceeding  for review shall be pending or a stay of  execution  shall have been
obtained,  or  which  are  otherwise  being  contested  in  good  faith  and  by
appropriate  proceedings,  or (iv) purchase  money liens,  equipment  leases and
financings incurred in the ordinary course of business.

                  (c)  Sale  and   Lease-Back   Transactions.   Enter  into  any
arrangement,  directly or  indirectly,  with any person whereby it shall sell or
transfer any property, real or personal, used or useful in its business, whether
now owned or hereafter  acquired,  and thereafter rent  (including  intellectual
property),  lease or license such property or other property which it intends to
use for substantially the same purpose or purposes as the property being sold or
transferred.

                  (d) Mergers, Consolidations, Sales of Assets and Acquisitions.
Merge into or consolidate  with any other person,  or permit any other person to
merge into or consolidate with it, or sell, transfer, lease or otherwise dispose
of (in one transaction or in a series of transactions) all or a substantial part
of its assets  (whether now owned or hereafter  acquired) or purchase,  lease or
otherwise  acquire (in one  transaction  or a series of  transactions)  all or a
substantial part of the assets of any other person.

                  (e) Dividends and  Distributions.  Declare or pay, directly or
indirectly, any dividend or make any other distribution (by reduction of capital
or otherwise),  whether in cash, property,  securities or a combination thereof,
with  respect to any  shares of its  capital  stock or  directly  or  indirectly
redeem, purchase,  retire or otherwise acquire for value any shares of any class
of its  capital  stock or set aside any amount for any such  purpose,  except as
permitted by Section 7.15 of the Note and Warrant Agreement.

                  (f) No  Impairment.  By  amendment  of its  charter or through
reorganization,  consolidation, merger, dissolution, sale of assets or any other
voluntary action, avoid or seek to avoid the observance or performance of any of
the  terms of this  Note,  but will at all  times in good  faith  assist  in the
carrying out of all such terms and in the taking of all such action as



                                       10

<PAGE>



may be necessary or  appropriate in order to protect the rights of the Holder of
this Note against impairment.


SECTION 7.          EVENTS OF DEFAULT DEFINED.

                  The  following  shall each  constitute  an "Event of  Default"
hereunder:

                  (a) the failure of the Company to make any payment of 
principal of or interest on this Note when due and payable;

                  (b) the  failure of the  Company  to  observe  or perform  any
covenant in this Note or in the Purchase Agreement,  and such failure shall have
continued unremedied for a period of five (5) days;

                  (c)  if the Company shall:

                           (1)      admit in writing its inability to pay its 
                                    debts generally as they become due,

                           (2)      file a petition in bankruptcy or a petition 
                                    to take advantage of any insolvency act,

                           (3)      make an assignment for the benefit of its 
                                    creditors,

                           (4)      consent to the appointment of a receiver of
                                    itself  or of the whole or any  substantial
                                    part of its property,

                           (5)      on a petition in bankruptcy filed against, 
                                    be adjudicated a bankrupt, or

                           (6)      file   a   petition   or   answer    seeking
                                    reorganization   or  arrangement  under  the
                                    federal   bankruptcy   laws  or  any   other
                                    applicable  law or  statute  of  the  United
                                    States of America or any state thereof;

                  (d) if a court of competent jurisdiction shall enter an order,
judgment or decree appointing, without the consent of the Company, a receiver of
the  Company  or of the  whole  or any  substantial  part  of its  property,  or
approving a petition filed against it seeking  reorganization  or arrangement of
the Company under the federal  bankruptcy  laws or any other  applicable  law or
statute of the United  States of America or any State  thereof,  and such order,
judgment  or decree  shall not be vacated or set aside or stayed  within  thirty
(30) days from the date of entry thereof;




                                       11

<PAGE>



                  (e) if, under the  provisions  of any other law for the relief
or aid of debtors,  any court of competent  jurisdiction shall assume custody or
control of the Company or the whole or any substantial  part of its property and
such custody or control  shall not be  terminated  or stayed  within thirty (30)
days from the date of assumption of such custody or control;

                  (f) the liquidation, dissolution or winding up of the Company;

                  (g) the failure of the  shareholders  to authorize and approve
the  issuance of these Notes or the  issuance of the shares of  Preferred  Stock
underlying  these Notes,  the Bridge Warrants or the New Warrants (as such terms
are defined in the  Purchase  Agreement),  or any Common  Stock  underlying  the
foregoing to the extent such authorization is necessary pursuant to the rules of
the Nasdaq National Market or any other applicable law, rule or regulation.

                  (h) A  default  or  event of  default  which  remains  uncured
following any applicable cure period under the Security Agreement; or

                  (i) A final  judgment or judgments for the payment of money in
excess of $1,000,000  in the aggregate  shall be rendered by one or more courts,
administrative or arbitral tribunals or other bodies having jurisdiction against
the Company and the same shall not be discharged (or provision shall not be made
for such  discharge),  or a stay of  execution  thereof  shall not be  procured,
within 30 days from the date of entry thereof and the Company shall not,  within
such 30-day  period,  or such longer period  during which  execution of the same
shall have been stayed,  appeal therefrom and cause the execution  thereof to be
stayed during such appeal; or

SECTION 8.          REMEDIES UPON EVENT OF DEFAULT.

                  (a) Upon the occurrence of an Event of Default, (i) the entire
principal  amount of, and all  accrued and unpaid  interest  on, this Note shall
automatically  become immediately due and payable without  presentment,  demand,
protest or other  formalities  of any kind,  all of which are  hereby  expressly
waived by the Company and (ii)  additional  interest shall begin to accrue,  and
shall be considered  immediately due and payable, on the unpaid principal amount
of this Note at the rate of eighteen  percent (18%) per annum and shall continue
to accrue  until the  initial  interest  and  additional  interest  is paid.  In
addition,  the  Holder may take any action  available  to it under the  Purchase
Agreement or at law or in equity or by statute or otherwise.

                  (b) No remedy herein conferred upon the Holder of this Note is
intended  to be  exclusive  of any other  remedy and each and every such  remedy
shall be  cumulative  and  shall be in  addition  to every  other  remedy  given
hereunder  or now or  hereafter  existing  at law or in equity or by  statute or
otherwise.





                                       12

<PAGE>



SECTION 9.          NOTE REGISTER.

                  (a) The Company shall keep at its principal executive office a
register  (herein  sometimes  referred  to as the  "Note  Register"),  in which,
subject to such reasonable  regulations as it may prescribe,  but at its expense
(other  than  transfer  taxes,  if  any),  the  Company  shall  provide  for the
registration and transfer of this Note.

                  (b) Whenever this Note shall be  surrendered  at the principal
executive  office of the Company  for  transfer or  exchange,  accompanied  by a
written  instrument of transfer in form  reasonably  satisfactory to the Company
duly executed by the Holder  hereof or his attorney duly  authorized in writing,
the Company shall execute and deliver in exchange  therefor a new Note or Notes,
as may be requested  by such  Holder,  in the same  aggregate  unpaid  principal
amount and payable on the same date as the principal amount of the Note or Notes
so  surrendered;  each  such  new  Note  shall  be dated as of the date to which
interest  has been paid on the unpaid  principal  amount of the Note or Notes so
surrendered and shall be in such principal amount and registered in such name or
names as such Holder may designate in writing.

                  (c)  Upon  receipt  by  the  Company  of  evidence  reasonably
satisfactory  to it of the loss,  theft,  destruction or mutilation of this Note
and of indemnity  reasonably  satisfactory to it, and upon  reimbursement to the
Company of all reasonable expenses  incidental  thereto,  and upon surrender and
cancellation  of this Note (in case of  mutilation)  the  Company  will make and
deliver  in lieu of this  Note a new Note of like  tenor  and  unpaid  principal
amount  and dated as of the date to which  interest  has been paid on the unpaid
principal  amount  of this  Note in lieu of  which  such  new  Note is made  and
delivered.

SECTION 10.         REGISTRATION UNDER SECURITIES ACT OF 1933.

                  The  Holder of this Note  shall  have  registration  rights as
provided in Section 8 of the Purchase  Agreement,  with respect to the shares of
Common Stock  underlying  the Preferred  Stock  issuable upon  conversion of the
Notes pursuant to the Optional and Default  Conversion  Right.  If the Holder is
not a party to the Purchase  Agreement,  by acceptance of this Note,  the Holder
agrees to comply with  provisions of Section 8 of the Purchase  Agreement to the
same extent as if it were a party thereto.

SECTION 11.       MISCELLANEOUS.

                  (a)  Amendments  and  Waivers.  The holders of  sixty-six  and
two-thirds percent (66 2/3%) or more in principal amount of outstanding Notes of
this  issue  may  waive or  otherwise  consent  to the  amendment  of any of the
provisions  hereof,  provided  that no such waiver or  amendment  may reduce the
principal  amount of or interest on any of the Notes of this issue or change the
stated maturity of the principal or reduce the percentage of holders of Notes of
this issue necessary to waive or amend the provisions of this Note,  without the
consent of each holder of any Note affected thereby.




                                       13

<PAGE>




                  (b)  Restrictions  on  Transferability.  In  addition  to  the
restrictions set forth in Section 9(a) of this Note, the securities  represented
by this Note have been  acquired  for  investment  and have not been  registered
under the  Securities  Act of 1933, as amended,  or the  securities  laws of any
state or other jurisdiction.  Without such registration, such securities may not
be sold,  pledged,  hypothecated  or otherwise  transferred,  except pursuant to
exemptions from the Securities Act of 1933, and the securities laws of any state
or other  jurisdiction.  Notwithstanding  the above, the holder of this Note has
been  provided the  registration  rights  contained in Section 8 of the Purchase
Agreement with respect to the shares of the Company's  Common Stock which may be
acquired upon exercise of the Optional and Default Conversion Right.

                  (c)  Forbearance  from Suit.  No holder of Notes of this issue
shall  institute any suit or proceeding  for the  enforcement  of the payment of
principal or interest unless the holders of at least fifty-one  percent (51%) in
principal amount of all of the outstanding Notes of this issue join in such suit
or proceeding.

                  (d)  Governing  Law.  This  Note  shall  be  governed  by  and
construed in  accordance  with the laws of the State of New York,  excluding the
body of law  relating  to  conflict  of laws.  Notwithstanding  anything  to the
contrary  contained  herein,  in no event  may the  effective  rate of  interest
collected or received by the Holder exceed that which may be charged,  collected
or received by the Holder under applicable law.

                  (e)  Interpretation.  If any term or  provision  of this  Note
shall be held invalid, illegal or unenforceable, the validity of all other terms
and provisions hereof shall in no way be affected thereby.

                  (f) Successors and Assigns.  This Note shall be binding upon 
the Company and its successors and assigns and shall inure to the benefit of the
Holder and its successors and assigns.

                  (g) Notices. All notices, requests, consents and demands shall
be made in writing and shall be mailed postage prepaid, or delivered by hand, to
the Company or to the Holder  thereof at their  respective  addresses  set forth
below or to such other address as may be furnished in writing to the other party
hereto:

                  If to the Holder:  At the address shown on Schedule A attached
hereto.

                  with a copy to:    Paramount Capital, Inc.
                                     787 Seventh Avenue
                                     New York, NY 10019
                                     Attn: David R. Walner

                  If to the Company: Genta Incorporated
                                     3350 General Atomics Court



                                       14

<PAGE>



                               San Diego, CA 92121
                               Attention: Chief Executive Officer

                  (h) Saturdays,  Sundays, Holidays. If any date that may at any
time be  specified  in this  Note as a date for the  making  of any  payment  of
principal or interest under this Note shall fall on Saturday, Sunday or on a day
which in New York shall be a legal holiday, then the date for the making of that
payment  shall be the next  subsequent  day which is not a  Saturday,  Sunday or
legal holiday.

                  (i)  Purchase  Agreement.  This Note is  subject  to the terms
contained in the Purchase  Agreement  dated the date hereof  between the Company
and certain  purchasers of the Senior Secured  Convertible  Bridge Notes and the
holder of this Note is entitled to the benefits of such  Purchase  Agreement and
may, in addition to any rights hereunder,  enforce the agreements of the Company
contained  therein and exercise  the remedies  provided for thereby or otherwise
available in respect thereof.




                                       15

<PAGE>


         IN WITNESS  WHEREOF,  this Note has been  executed  and  delivered as a
sealed  instrument  on the date  first  above  written  by the  duly  authorized
representative of the Company.


ATTEST:                                     GENTA INCORPORATED


_______________________             By:     ________________________________
                                            Name:
                                            Its:



(Corporate Seal)




                                       16

<PAGE>

                                    EXHIBIT S

THIS NOTE IS NOT  TRANSFERABLE  WITHOUT  THE  EXPRESS  WRITTEN  CONSENT OF GENTA
INCORPORATED,  (THE "COMPANY"). THE SECURITIES REPRESENTED BY THIS NOTE HAVE NOT
BEEN  REGISTERED  UNDER  THE  SECURITIES  ACT OF  1933 OR ANY  APPLICABLE  STATE
SECURITIES LAWS, AND MAY NOT BE SOLD,  OFFERED FOR SALE, PLEDGED OR HYPOTHECATED
OR OTHERWISE  TRANSFERRED IN THE ABSENCE OF A  REGISTRATION  STATEMENT IN EFFECT
WITH RESPECT TO THE  SECURITIES  UNDER SUCH ACT OR AN EXEMPTION  THEREFROM.  ANY
SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE STATE SECURITIES LAWS.


                               GENTA INCORPORATED

                                                                         No. B-2
           AMENDED AND RESTATED SENIOR SECURED CONVERTIBLE BRIDGE NOTE

$1,950,000                                                  New York, New York
                                                            January 28, 1997, as
                                                            amended and restated
                                                            on June 23, 1997

                  Genta Incorporated,  a Delaware corporation,  (the "Company"),
for value received, hereby promises to pay to THE ARIES TRUST (the "Holder"), or
registered assigns, the principal sum of ONE MILLION NINE HUNDRED FIFTY THOUSAND
DOLLARS  ($1,950,000),  with interest from the date of original issuance of this
Senior Secured Convertible Bridge Note on the unpaid principal balance at a rate
equal to twelve  percent  (12%) per annum,  on the earlier of (a)  December  31,
1997,  (b)  September  30,  1997 if on or prior to such date the Company has not
received  gross  proceeds of at least  $2,000,000  in respect of its offering of
Premium Preferred Units which was commenced in May, 1997 and (c) the date of any
decision,  order or other  determination  adverse  to the  Company or any of its
directors  by any court or other  tribunal  in any  lawsuit or other  proceeding
against  the  Company  and/or  any of  its  directors  by  any of the  Company's
preferred  stockholders,  including,  without limitation,  any adverse result or
other determination in connection with an appeal of the decision rendered by the
Delaware Court of Chancery in May, 1997 in respect of the suit described in Item
3 of the Company's Form 10-K for the year ended December 31, 1996 (such earliest
date, the "Maturity Date"). Payment shall be made at such place as designated by
the Holder upon  surrender of this Senior Secured  Convertible  Bridge Note, and
shall be in such coin or currency of the United States of America as at the time
of payment  shall be legal  tender for the payment of public and private  debts.
Interest  shall be  computed  on the  basis of a 360-day  year of twelve  30-day
months.  This Senior Secured Convertible Bridge Note is one of a duly authorized
issue of Genta  Incorporated 12% Senior Convertible Bridge Notes in an aggregate
principal amount of $3,000,000 (individually a "Note"




<PAGE>



and  collectively  the "Notes") issued  pursuant to a Note and Warrant  Purchase
Agreement  dated  January  28,  1997  between  the  Company  and the Holder (the
"Purchase  Agreement").  The Senior  Secured  Convertible  Bridge Notes shall be
senior to all other  indebtedness of the Company ("Other  Indebtedness") and all
Other Indebtedness shall be subordinated to the Senior Bridge Notes. These Notes
are secured  pursuant to the Security  Agreement dated as of January 28, 1997 by
and between the Company, Paramount Capital, Inc. and the Purchasers.

SECTION 1.        PREPAYMENT.

                  This Note (including interest accrued on the principal hereof)
may be prepaid by the Company,  at any time without penalty or premium  provided
that the  Company  shall  provide the holders of the Notes with at least 30 days
prior written notice of prepayment, and prior to such prepayment, the holders of
the Notes shall have the  opportunity  to  exercise  their  optional  conversion
rights pursuant to Section 2 hereof.

SECTION 2.        OPTIONAL CONVERSION

                  (a) Right of  Conversion.  (i)  Immediately,  or,  (ii) if the
rules of the Nasdaq National Market or any other law or regulation,  require the
approval  of the  shareholders  of the Company to permit  convertibility  of the
Notes, then upon the receipt of such approvals,  the Notes shall be convertible,
in whole or in part, at the option of the holder  thereof and upon notice to the
Corporation as set forth in paragraph  2(b) below,  into the number of shares of
Series D Preferred  Stock of the Company (the  "Preferred  Stock")  equal to the
Conversion  Amount  divided by the then  current  Conversion  Price (as  defined
below). The Conversion Amount shall be the Liquidation Amount, or in the case of
a partial conversion, such lesser amount as designated by the converting holder.
The Liquidation Amount shall be the aggregate  principal value of the Notes held
by such Holder plus any accrued and unpaid interest.  The Conversion Price shall
initially be $50.00,  subject to adjustment as provided  below,  representing an
initial conversion rate (subject to adjustment) of 200 shares of Preferred Stock
per $10,000 of  Conversion  Amount.  Notwithstanding  anything  to the  contrary
contained in this Note,  no right of  conversion  shall exist if and only to the
extent that such  conversion  would result in the  occurrence of a  "Fundamental
Change"  under  Article  IV  of  the  Corporation's   Restated   Certificate  of
Incorporation.

                  (b)  Conversion  Procedures.  Any holder of Notes  desiring to
convert such Notes into Preferred Stock shall surrender the Notes at the offices
of the Company,  which Notes shall be accompanied by irrevocable  written notice
to the  Corporation  that  the  holder  elects  so to  convert  such  Notes  and
specifying  the  name  or  names  (with  address)  in  which  a  certificate  or
certificates  evidencing  shares  of  Preferred  Stock  are  to be  issued.  The
Corporation  will make a  notation  of the date that a notice of  conversion  is
received,  which  date shall be deemed to be the date of  receipt  for  purposes
hereof.

                  The  Corporation  shall deliver to the holder  converting  the
Notes, or to the nominee or nominees of such person, certificates evidencing the
number of full shares of



                                        2

<PAGE>



Preferred  Stock to which such person shall be entitled as  aforesaid,  together
with a cash  adjustment  of any  fraction  of a share as  hereinafter  provided.
Subject to the following provisions of this paragraph,  such conversion shall be
deemed to have been made as of the date of such  surrender  of the Notes and the
person or persons  entitled  to receive the  Preferred  Stock  deliverable  upon
conversion  of such Notes shall be treated for all purposes as the record holder
or holders of such Preferred  Stock on such date;  provided,  however,  that the
Corporation  shall not be required to convert any Notes while the stock transfer
books of the Corporation are closed for any purpose,  but the surrender of Notes
for  conversion  during any period  while such books are so closed  shall become
effective for conversion  immediately upon the reopening of such books as if the
surrender had been made on the date of such reopening,  and the conversion shall
be at the conversion rate in effect on such date.

                  All  notices of  conversion  shall be  irrevocable;  provided,
however,  that if the  Corporation  has  sent  notice  of an event  pursuant  to
paragraph  2(e) hereof,  a holder of Notes may, at its election,  provide in its
notice of conversion  that the conversion of its Notes shall be contingent  upon
the occurrence of the record date or  effectiveness  of such event (as specified
by such  holder),  provided  that such notice of  conversion  is received by the
Corporation prior to such record date or effective date, as the case may be.

                  (c) Protection From Dilution. (i) If, at any time or from time
to time after the date of this Note,  the Company  shall issue or  distribute to
the holders of shares of Preferred Stock evidence of its indebtedness, any other
securities  of the Company or any cash,  property or other  assets  (excluding a
subdivision,  combination  or  reclassification,  or  dividend  or  distribution
payable  solely to  holders of  Preferred  Stock in shares of  Preferred  Stock,
referred to in Subsection  (c)(ii),  and also  excluding  cash dividends or cash
distributions  paid out of net profits  legally  available  therefor in the full
amount  thereof  (any such  non-excluded  event being  herein  called a "SPECIAL
DIVIDEND"), the Conversion Price shall be adjusted by multiplying the Conversion
Price then in effect by a  fraction,  the  numerator  of which shall be the then
Current  Market Price Per Share of Preferred  Stock in effect on the record date
of such issuance or  distribution  less the fair market value (as  determined in
good faith by the Company's Board of Directors) of the evidence of indebtedness,
cash,  securities  or property,  or other assets issued or  distributed  in such
Special Dividend  applicable to one share of Preferred Stock and the denominator
of which shall be the then Current Market Price Per Share of Preferred  Stock in
effect on the record date of such issuance or  distribution.  An adjustment made
pursuant to this Subsection 2(a) shall become  effective  immediately  after the
record date of any such Special  Dividend.  The then  "CURRENT  MARKET PRICE PER
SHARE OF PREFERRED  STOCK" shall equal the then Current Market Price  multiplied
by the then effective  "conversion rate" (as defined and used in the Certificate
of Designation for the Preferred Stock).

The then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed, or if not listed or admitted to trading



                                        3

<PAGE>



on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined in good faith by the Board of Directors.

                  (ii) In case the Company shall hereafter (i) pay a dividend or
make a  distribution  on its capital  stock in shares of Preferred  Stock,  (ii)
subdivide its  outstanding  shares of Preferred  Stock into a greater  number of
shares,  (iii) combine its outstanding  shares of Preferred Stock into a smaller
number of shares or (iv) issue by  reclassification  of its Preferred  Stock any
shares of capital stock of the Company (other than the Conversion  Shares),  the
Conversion  Price shall be  proportionately  adjusted so that the Notes shall be
convertible  into a number and kind of  securities  which the holders would have
been  entitled  to  receive  after any such event had they  converted  the Notes
immediately  prior  thereto.  An  adjustment  made  pursuant to this  Subsection
2(c)(ii) shall become effective immediately after the record date in the case of
a dividend or  distribution  and shall become  effective  immediately  after the
effective date in the case of a subdivision, combination or reclassification.

                  (iii) Except as provided in Subsections (c)(i) and (c)(iv), in
case  the  Company  shall  hereafter  issue  or sell any  Preferred  Stock,  any
securities  convertible into Preferred Stock, any rights, options or warrants to
purchase Preferred Stock or any securities  convertible into Preferred Stock, in
each case for a price per share or  entitling  the  holders  thereof to purchase
Preferred  Stock at a price  per share  (determined  by  dividing  (i) the total
amount,  if any,  received or receivable by the Company in  consideration of the
issuance  or sale of such  securities  plus  the  total  consideration,  if any,
payable  to  the  Company  upon  exercise  or  conversion  thereof  (the  "TOTAL
CONSIDERATION")  by (ii) the  number of  additional  shares of  Preferred  Stock
issuable  upon exercise or  conversion  of such  securities)  which is less than
either the then Current  Market Price Per Share of Preferred  Stock in effect on
the date of such issuance or sale or the Conversion  Price, the Conversion Price
shall be adjusted as of the date of such  issuance  or sale by  multiplying  the
Conversion  Price then in effect by a fraction,  the numerator of which shall be
(x) the sum of (A) the number of shares of Preferred  Stock  outstanding  on the
record date of such issuance or sale plus (B) the Total Consideration divided by
the Current Market Price Per Share of Preferred Stock or the current  Conversion
Price,  whichever  is  greater,  and the  denominator  of which shall be (y) the
number of shares of  Preferred  Stock  outstanding  on the  record  date of such
issuance or sale plus the maximum number of additional shares of Preferred Stock
issued, sold or issuable upon exercise or conversion of such securities.

                  (iv)   In   case   of   any    capital    reorganization    or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or substantially as a entirety, or in the
case of any statutory exchange of securities with another corporation (including
any exchange effected in



                                        4

<PAGE>



connection with a merger of a third corporation into the Company), the Holder of
this Note shall have the right  thereafter to receive on the  conversion of this
Note the kind and amount of securities,  cash or other property which the Holder
would  have  owned or have been  entitled  to  receive  immediately  after  such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or  conveyance  had  this  Note  been  converted  immediately  prior to the
effective date of such reorganization, reclassification,  consolidation, merger,
statutory  exchange,  sale or  conveyance  and in any such case,  if  necessary,
appropriate  adjustment  shall be made in the  application of the provisions set
forth in this Section 2 with respect to the rights and  interests  thereafter of
the Holder of this Note to the end that the provisions set forth in this Section
2  shall  thereafter  correspondingly  be  made  applicable,  as  nearly  as may
reasonably  be,  in  relation  to any  shares  of stock or other  securities  or
property  thereafter  deliverable  on the  Note.  The above  provisions  of this
Subsection   (c)(iv)  shall  similarly  apply  to  successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The  Company  shall  require  the issuer of any shares of stock or
other securities or property thereafter deliverable on the exercise of this Note
to be  responsible  for all of the  agreements  and  obligations  of the Company
hereunder. Notice of any such reorganization,  reclassification,  consolidation,
merger,  statutory  exchange,  sale  or  conveyance  and of said  provisions  so
proposed  to be made,  shall be mailed to the Holders of the Notes not less than
30 days prior to such event. A sale of all or substantially all of the assets of
the Company for a  consideration  consisting  primarily of  securities  shall be
deemed a consolidation or merger for the foregoing purposes.

                  (v) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 2 are not strictly  applicable  but as to which the
failure to make any adjustment  would not fairly  protect the conversion  rights
represented by this Note in accordance with the essential  intent and principles
hereof  then,  in each such case,  the  Holders  of Notes may  appoint a firm of
independent  public  accountants  of  recognized  national  standing  reasonably
acceptable to the Company,  which shall give their opinion as to the adjustment,
if  any,  on a  basis  consistent  with  the  essential  intent  and  principles
established herein, necessary to preserve the conversion rights. Upon receipt of
such  opinion,  the Company will  promptly  mail a copy thereof to the Holder of
this  Note  and  shall  make the  adjustments  described  therein.  The fees and
expenses of such independent public accountants shall be borne by the Company.

                  (vi) For purposes of the anti-dilution protection contained in
this  Section  (c),  at all times  following  the  conversion  of all  shares of
Preferred  Stock into shares of Common Stock,  the term Preferred Stock shall be
read  to  be  Common  Stock,  context  permitting,  so  that  the  anti-dilution
provisions  will continue to protect the conversion  rights  represented by this
Note after the  conversion of all the  Preferred  Stock into the Common Stock in
accordance with the essential  intent and principles of this Section 3 (it being
understood that prior to such conversion,  the  anti-dilution  provisions of the
Preferred Stock  underlying this Note shall be applicable to any dilutive events
with  respect to the Common  Stock and protect  the Holder from  dilution of the
Common Stock).




                                        5

<PAGE>



                  (d)   Reservation  of  Shares;   Transfer   Taxes;   Etc.  The
Corporation shall at all times reserve and keep available, out of its authorized
and unissued shares of Preferred Stock,  solely for the purpose of effecting the
conversion of the Notes,  such number of shares of its  Preferred  Stock free of
preemptive  rights as shall be sufficient to effect the  conversion of all Notes
from time to time  outstanding.  The Corporation shall use its best efforts from
time to time, in accordance with the laws of the State of Delaware,  to increase
the authorized  number of shares of Preferred Stock if at any time the number of
shares of Preferred Stock not outstanding  shall not be sufficient to permit the
conversion of all the then-outstanding Notes.

                  The  Corporation  shall pay any and all  issue or other  taxes
that may be payable in respect of any issue or delivery  of shares of  Preferred
Stock on  conversion  of the  Notes.  The  Corporation  shall not,  however,  be
required to pay any tax which may be payable in respect of any transfer involved
in the issue or delivery of Preferred Stock (or other securities or assets) in a
name other than that in which the Notes so  converted  were  registered,  and no
such issue or delivery shall be made unless and until the person requesting such
issue has paid to the Corporation the amount of such tax or has established,  to
the satisfaction of the Corporation, that such tax has been paid.

                  (e)     Prior Notice of Certain Events.  In case:

                    (i)   the Corporation shall declare any dividend (or any 
         other distribution); or

                    (ii)  the  Corporation  shall  authorize  the granting to 
         the holders of  Preferred  Stock of rights or warrants to  subscribe
         for or  purchase  any  shares  of stock of any class or of any other
         rights or warrants; or

                    (iii) of any reclassification of Preferred Stock (other than
         a subdivision or combination of the outstanding  Preferred  Stock, or a
         change in par value,  or from par value to no par value, or from no par
         value to par value); or

                    (iv)  of any consolidation or merger to which the 
         Corporation is a party and for which approval of any stockholders of
         the Corporation shall be required, or of the sale or transfer of all
         or  substantially  all of the  assets of the  Corporation  or of any
         compulsory  share exchange  whereby the Preferred Stock is converted
         into other securities, cash or other property; or

                    (v)   of the voluntary or involuntary dissolution, 
         liquidation or winding up of the Corporation;

then the Corporation  shall cause to be mailed to the holders of Notes, at their
last addresses as they shall appear upon the books of the Corporation,  at least
20 days prior to the  applicable  record date  hereinafter  specified,  a notice
stating  (x) the date on which a record (if any) is to be taken for the  purpose
of such dividend, distribution or granting of rights or warrants or, if a record
is not to be  taken,  the date as of which the  holders  of  Preferred  Stock of
record to be



                                        6

<PAGE>



entitled to such dividend, distribution, rights or warrants are to be determined
and a description  of the cash,  securities or other  property to be received by
such holders upon such dividend,  distribution or granting of rights or warrants
or (y) the date on which such  reclassification,  consolidation,  merger,  sale,
transfer,  share  exchange,  dissolution,  liquidation  or  winding  up or other
liquidation  event is expected to become  effective,  the date as of which it is
expected that holders of Preferred Stock of record shall be entitled to exchange
their shares of Preferred  Stock for  securities or other  property  deliverable
upon such exchange, dissolution,  liquidation or winding up or other liquidation
event and the  consideration,  including  securities  or other  property,  to be
received by such holders upon such exchange;  provided, however, that no failure
to mail such notice or any defect therein or in the mailing thereof shall affect
the validity of the corporate action required to be specified in such notice.

                  (f) Other Changes in Conversion  Rate.  The  Corporation  from
time to time may  increase the  Conversion  Rate by any amount for any period of
time if the period is at least 20 days and if the increase is irrevocable during
the period. Whenever the Conversion Rate is so increased,  the Corporation shall
mail to  holders  of record of Notes a notice of the  increase  at least 15 days
before the date the  increased  Conversion  Rate takes  effect,  and such notice
shall state the increased Conversion Rate and the period it will be in effect.

                  The  Corporation  may make such  increases  in the  Conversion
Rate, in addition to those  required or allowed by this paragraph 4, as shall be
determined by it, as evidenced by a resolution of the Board of Directors,  to be
advisable  in order to avoid or  diminish  any  income  tax to holders of Common
Stock resulting from any dividend or distribution of stock or issuance of rights
or warrants to purchase or subscribe for stock or from any event treated as such
for income tax purposes.

SECTION 3.         DEFAULT CONVERSION.

                  (a) If this Note and all accrued  interest shall not have been
paid in full on or before the Maturity  Date or upon the  occurrence of an Event
of Default  (as  defined in Section 7 hereof),  the Holder  shall have the right
(the "Default  Conversion  Right"),  in addition to any other available remedies
set forth in  Section  8 hereof or at law or in  equity,  to  convert  up to the
lesser of (i) the then outstanding  principal amount of this Note or (ii) 10% of
the original  principal amount of this Note, into the number of shares of Common
Stock of the Company  ("Common  Stock"),  equal to the amount  converted  by the
Noteholder upon such Event of Default (the "Default  Conversion Amount") divided
by $.001 (the "Default  Conversion Price").  Upon conversion,  the Company shall
pay all accrued and unpaid interest on the Default Conversion Amount.

                  (b) To exercise the Default  Conversion  Right, the Holder, on
or before the 60th day after the Maturity  Date,  but before  payment in full of
the then  outstanding  principal and interest under this Note,  shall deliver to
the Company, at its office at as set forth in section 11, or at such other place
as is designated in writing by the Company,  a notice (the "Conversion  Notice")
stating that the Holder is exercising the Default Conversion Right, the Default



                                        7

<PAGE>



Conversion  Amount  and the  name or  names  in  which  the  Holder  wishes  the
certificates for shares of Common Stock to be issued.

                  (c) To the extent  permitted by applicable  law, upon exercise
of the Default  Conversion Right, the Holder shall be deemed to be the holder of
record  of  the  shares  of  Common  Stock  issuable  upon  such  exercise  (the
"Conversion  Shares"),  notwithstanding  that the transfer  books of the Company
shall then be closed or certificates  representing  such Conversion Shares shall
not then have been actually  delivered to the Holder. As soon as practicable and
in any event  within  five (5) days after  exercise  of the  Default  Conversion
Right,  the  Company  shall  issue and  deliver to the Holder a  certificate  or
certificates  evidencing  the  Conversion  Shares  registered in the name of the
Holder or its  designee,  provided  that the Company may require the holder,  by
notice given to the Holder promptly after receipt of the Conversion Notice, as a
condition to the delivery of such certificate or  certificates,  to present this
Note to the Company for the  placement  hereon of a legend  indicating  that the
Default  Conversion  Right  has been  exercised  to the  extent  of the  Default
Conversion  Amount,  and  this  Note  (unless  thereby  paid in  full)  shall be
immediately returned to the Holder.

                  (d) The  issuance of any shares or other  securities  upon the
exercise of the Default  Conversion  Right,  and the delivery of certificates or
other instruments  representing  such shares or other securities,  shall be made
without  charge to the  Holder  for any tax or other  charge in  respect of such
issuance.  The Company shall not, however,  be required to pay any tax which may
be payable in respect of any transfer  involved in the issue and delivery of any
certificate in a name other than that of the Holder and the Company shall not be
required to issue or deliver any such certificate unless and until the person or
persons  requesting  the issue thereof shall have paid to the Company the amount
of such tax or shall have  established to the  satisfaction  of the Company that
such tax has been paid.

                  (e) The  Holder  shall not have,  solely  on  account  of such
status as a Holder of this Note,  any rights of a  stockholder  of the  Company,
either at law or in equity,  or any notice of meetings of stockholders or of any
other proceedings of the Company except as provided in this Note.

                  (f) The  Company  shall at all times  following  the  Issuance
Date,  reserve and keep available out of its  authorized and unissued  shares of
Common  Stock,  solely for the  purpose of  providing  for the  exercise  of the
Default  Conversion  Right, such number of shares of Common Stock as shall, from
time to time, be sufficient for the exercise of the Default  Conversion Right in
full.  The  Company  covenants  that all shares of Common  Stock  issuable  upon
exercise of the Default Conversion Right shall be validly issued, fully paid and
nonassessable.

                  (g) The  anti-dilution  protections  set forth in Section 2(c)
hereof shall apply as well to the Default Conversion Right and the adjustment of
the Default Conversion Price hereunder,  provided, however, that for purposes of
such application all appropriate  references to Preferred Stock shall be read as
references to Common Stock and all references to the  Conversion  Price shall be
read as references to the Default Conversion Price, so as to give the Default



                                        8

<PAGE>



Conversion  Rights,  as  nearly  as  practicable,  the  anti-dilution  and other
protections provided for in section 2(c) with respect to the Optional Conversion
Right.

SECTION 4.         FRACTIONAL SHARES.

                  (a) The Company  shall not be required to issue  fractions  of
shares of Common Stock or other  capital  stock of the Company upon the exercise
of the Optional and Default  Conversion  Right. If any fraction of a share would
be issuable  on any  exercise of the  Optional or Default  Conversion  Right (or
specified  portions  thereof),  the Company shall  purchase such fraction for an
amount in cash equal to the same  fraction of the  closing  price for the Common
Stock on the  trading  date  immediately  preceding  the date of exercise of the
Optional or Default Conversion Right.

SECTION 5.        AFFIRMATIVE COVENANTS OF THE COMPANY.

                  The  Company  covenants  and agrees  that until the payment in
full of this Note, the Company shall:

                  (a) Existence; Business.  (i) Preserve, renew and keep in full
force and effect its legal existence and (ii) obtain,  preserve,  renew,  extend
and  keep in full  force  and  effect  the  licenses,  permits,  authorizations,
patents, trademarks and trade names material to its business.

                  (b) Use of  Proceeds.  Use the  proceeds  of the Notes of this
issue  solely  as set  forth in  Section  7.7 of the Note and  Warrant  Purchase
Agreement between the Company and various  purchasers dated the date hereof (the
"Purchase Agreement")

                  (c) Reports.  Furnish to the Holder,  at the time furnished to
the  Company's  stockholders,  reports  furnished  generally  to  the  Company's
stockholders, and copies of Current Reports on Form 8-K.

                  (d) Notice of Events of Default.  Furnish to the Holder prompt
written notice of any Event of Default, specifying the nature and extent thereof
and corrective action, if any, proposed to be taken with respect thereto.

                  (e) Authorization of Stock Issuable Upon Conversion.  No later
than the Maturity Date,  authorize and reserve a sufficient number of its shares
for exercise of the Default Conversion Right.

SECTION 6.        NEGATIVE COVENANTS OF THE COMPANY.

                  The  Company  covenants  and agrees with the Holder that until
the payment in full of this Note, the Company shall not:




                                        9

<PAGE>



                  (a) Indebtedness. Incur, create, assume or permit to exist any
indebtedness except (i) indebtedness represented by the Notes, (ii) indebtedness
which by its terms is  subordinated  to the Notes in an amount less than $25,000
in the  aggregate  (iii)  indebtedness  in an amount  less than  fifty  thousand
dollars  ($50,000)  incurred  in the  ordinary  course  of  business,  and  (iv)
indebtedness  for borrowed  money  existing on the date hereof and  disclosed in
writing to the Holder on or prior to the date  hereof,  but not any  extensions,
renewals or replacements of such indebtedness;

                  (b) Liens.  Create,  incur, assume or permit to exist any lien
on any property or assets  (including  stock or other  securities of any person)
now owned or hereafter  acquired by the Company,  except (i) liens for taxes not
yet due or which are being contested by appropriate proceedings; (ii) carriers',
warehousemen's,  mechanic's,  materialmen's,  repairmen's  or other  like  liens
arising in the ordinary course of business and securing obligations that are not
due or which are being  contested;  or (iii) liens of attachments,  judgments or
awards against the Company (X) which could not reasonably be expected to have an
adverse material effect on the Company or (Y) with respect to which an appeal or
proceeding  for review shall be pending or a stay of  execution  shall have been
obtained,  or  which  are  otherwise  being  contested  in  good  faith  and  by
appropriate  proceedings,  or (iv) purchase  money liens,  equipment  leases and
financings incurred in the ordinary course of business.

                  (c) Sale  and   Lease-Back   Transactions.   Enter  into  any
arrangement,  directly or  indirectly,  with any person whereby it shall sell or
transfer any property, real or personal, used or useful in its business, whether
now owned or hereafter  acquired,  and thereafter rent  (including  intellectual
property),  lease or license such property or other property which it intends to
use for substantially the same purpose or purposes as the property being sold or
transferred.

                  (d) Mergers, Consolidations, Sales of Assets and Acquisitions.
Merge into or consolidate  with any other person,  or permit any other person to
merge into or consolidate with it, or sell, transfer, lease or otherwise dispose
of (in one transaction or in a series of transactions) all or a substantial part
of its assets  (whether now owned or hereafter  acquired) or purchase,  lease or
otherwise  acquire (in one  transaction  or a series of  transactions)  all or a
substantial part of the assets of any other person.

                  (e) Dividends and  Distributions.  Declare or pay, directly or
indirectly, any dividend or make any other distribution (by reduction of capital
or otherwise),  whether in cash, property,  securities or a combination thereof,
with  respect to any  shares of its  capital  stock or  directly  or  indirectly
redeem, purchase,  retire or otherwise acquire for value any shares of any class
of its  capital  stock or set aside any amount for any such  purpose,  except as
permitted by Section 7.15 of the Note and Warrant Agreement.

                  (f) No  Impairment.  By  amendment  of its  charter or through
reorganization,  consolidation, merger, dissolution, sale of assets or any other
voluntary action, avoid or seek to avoid the observance or performance of any of
the  terms of this  Note,  but will at all  times in good  faith  assist  in the
carrying out of all such terms and in the taking of all such action as



                                       10

<PAGE>



may be necessary or  appropriate in order to protect the rights of the Holder of
this Note against impairment.


SECTION 7.        EVENTS OF DEFAULT DEFINED.

                  The  following  shall each  constitute  an "Event of  Default"
hereunder:

                  (a) the failure of the Company to make any payment of 
principal of or interest on this Note when due and payable;

                  (b) the  failure of the  Company  to  observe  or perform  any
covenant in this Note or in the Purchase Agreement,  and such failure shall have
continued unremedied for a period of five (5) days;

                  (c) if the Company shall:

                           (1)      admit in writing its inability to pay its 
                                    debts generally as they become due,

                           (2)      file a petition in bankruptcy or a petition 
                                    to take advantage of any insolvency act,

                           (3)      make an assignment for the benefit of its 
                                    creditors,

                           (4)      consent to the appointment of a receiver of 
                                    itself  or of the whole or any  substantial
                                    part of its property,

                           (5)      on a petition in bankruptcy filed against, 
                                    be adjudicated a bankrupt, or

                           (6)      file   a   petition   or   answer    seeking
                                    reorganization   or  arrangement  under  the
                                    federal   bankruptcy   laws  or  any   other
                                    applicable  law or  statute  of  the  United
                                    States of America or any state thereof;

                  (d) if a court of competent jurisdiction shall enter an order,
judgment or decree appointing, without the consent of the Company, a receiver of
the  Company  or of the  whole  or any  substantial  part  of its  property,  or
approving a petition filed against it seeking  reorganization  or arrangement of
the Company under the federal  bankruptcy  laws or any other  applicable  law or
statute of the United  States of America or any State  thereof,  and such order,
judgment  or decree  shall not be vacated or set aside or stayed  within  thirty
(30) days from the date of entry thereof;




                                       11

<PAGE>



                  (e) if, under the  provisions  of any other law for the relief
or aid of debtors,  any court of competent  jurisdiction shall assume custody or
control of the Company or the whole or any substantial  part of its property and
such custody or control  shall not be  terminated  or stayed  within thirty (30)
days from the date of assumption of such custody or control;

                  (f) the liquidation, dissolution or winding up of the Company;

                  (g) the failure of the  shareholders  to authorize and approve
the  issuance of these Notes or the  issuance of the shares of  Preferred  Stock
underlying  these Notes,  the Bridge Warrants or the New Warrants (as such terms
are defined in the  Purchase  Agreement),  or any Common  Stock  underlying  the
foregoing to the extent such authorization is necessary pursuant to the rules of
the Nasdaq National Market or any other applicable law, rule or regulation.

                  (h) A  default  or  event of  default  which  remains  uncured
following any applicable cure period under the Security Agreement; or

                  (i) A final  judgment or judgments for the payment of money in
excess of $1,000,000  in the aggregate  shall be rendered by one or more courts,
administrative or arbitral tribunals or other bodies having jurisdiction against
the Company and the same shall not be discharged (or provision shall not be made
for such  discharge),  or a stay of  execution  thereof  shall not be  procured,
within 30 days from the date of entry thereof and the Company shall not,  within
such 30-day  period,  or such longer period  during which  execution of the same
shall have been stayed,  appeal therefrom and cause the execution  thereof to be
stayed during such appeal; or

SECTION 8.        REMEDIES UPON EVENT OF DEFAULT.

                  (a) Upon the occurrence of an Event of Default, (i) the entire
principal  amount of, and all  accrued and unpaid  interest  on, this Note shall
automatically  become immediately due and payable without  presentment,  demand,
protest or other  formalities  of any kind,  all of which are  hereby  expressly
waived by the Company and (ii)  additional  interest shall begin to accrue,  and
shall be considered  immediately due and payable, on the unpaid principal amount
of this Note at the rate of eighteen  percent (18%) per annum and shall continue
to accrue  until the  initial  interest  and  additional  interest  is paid.  In
addition,  the  Holder may take any action  available  to it under the  Purchase
Agreement or at law or in equity or by statute or otherwise.

                  (b) No remedy herein conferred upon the Holder of this Note is
intended  to be  exclusive  of any other  remedy and each and every such  remedy
shall be  cumulative  and  shall be in  addition  to every  other  remedy  given
hereunder  or now or  hereafter  existing  at law or in equity or by  statute or
otherwise.





                                       12

<PAGE>



SECTION 9.         NOTE REGISTER.

                  (a) The Company shall keep at its principal executive office a
register  (herein  sometimes  referred  to as the  "Note  Register"),  in which,
subject to such reasonable  regulations as it may prescribe,  but at its expense
(other  than  transfer  taxes,  if  any),  the  Company  shall  provide  for the
registration and transfer of this Note.

                  (b) Whenever this Note shall be  surrendered  at the principal
executive  office of the Company  for  transfer or  exchange,  accompanied  by a
written  instrument of transfer in form  reasonably  satisfactory to the Company
duly executed by the Holder  hereof or his attorney duly  authorized in writing,
the Company shall execute and deliver in exchange  therefor a new Note or Notes,
as may be requested  by such  Holder,  in the same  aggregate  unpaid  principal
amount and payable on the same date as the principal amount of the Note or Notes
so  surrendered;  each  such  new  Note  shall  be dated as of the date to which
interest  has been paid on the unpaid  principal  amount of the Note or Notes so
surrendered and shall be in such principal amount and registered in such name or
names as such Holder may designate in writing.

                  (c)  Upon  receipt  by  the  Company  of  evidence  reasonably
satisfactory  to it of the loss,  theft,  destruction or mutilation of this Note
and of indemnity  reasonably  satisfactory to it, and upon  reimbursement to the
Company of all reasonable expenses  incidental  thereto,  and upon surrender and
cancellation  of this Note (in case of  mutilation)  the  Company  will make and
deliver  in lieu of this  Note a new Note of like  tenor  and  unpaid  principal
amount  and dated as of the date to which  interest  has been paid on the unpaid
principal  amount  of this  Note in lieu of  which  such  new  Note is made  and
delivered.

SECTION 10.       REGISTRATION UNDER SECURITIES ACT OF 1933.

                  The  Holder of this Note  shall  have  registration  rights as
provided in Section 8 of the Purchase  Agreement,  with respect to the shares of
Common Stock  underlying  the Preferred  Stock  issuable upon  conversion of the
Notes pursuant to the Optional and Default  Conversion  Right.  If the Holder is
not a party to the Purchase  Agreement,  by acceptance of this Note,  the Holder
agrees to comply with  provisions of Section 8 of the Purchase  Agreement to the
same extent as if it were a party thereto.

SECTION 11.       MISCELLANEOUS.

                  (a)  Amendments  and  Waivers.  The holders of  sixty-six  and
two-thirds percent (66 2/3%) or more in principal amount of outstanding Notes of
this  issue  may  waive or  otherwise  consent  to the  amendment  of any of the
provisions  hereof,  provided  that no such waiver or  amendment  may reduce the
principal  amount of or interest on any of the Notes of this issue or change the
stated maturity of the principal or reduce the percentage of holders of Notes of
this issue necessary to waive or amend the provisions of this Note,  without the
consent of each holder of any Note affected thereby.




                                       13

<PAGE>




                  (b)  Restrictions  on  Transferability.  In  addition  to  the
restrictions set forth in Section 9(a) of this Note, the securities  represented
by this Note have been  acquired  for  investment  and have not been  registered
under the  Securities  Act of 1933, as amended,  or the  securities  laws of any
state or other jurisdiction.  Without such registration, such securities may not
be sold,  pledged,  hypothecated  or otherwise  transferred,  except pursuant to
exemptions from the Securities Act of 1933, and the securities laws of any state
or other  jurisdiction.  Notwithstanding  the above, the holder of this Note has
been  provided the  registration  rights  contained in Section 8 of the Purchase
Agreement with respect to the shares of the Company's  Common Stock which may be
acquired upon exercise of the Optional and Default Conversion Right.

                  (c)  Forbearance  from Suit.  No holder of Notes of this issue
shall  institute any suit or proceeding  for the  enforcement  of the payment of
principal or interest unless the holders of at least fifty-one  percent (51%) in
principal amount of all of the outstanding Notes of this issue join in such suit
or proceeding.

                  (d)  Governing  Law.  This  Note  shall  be  governed  by  and
construed in  accordance  with the laws of the State of New York,  excluding the
body of law  relating  to  conflict  of laws.  Notwithstanding  anything  to the
contrary  contained  herein,  in no event  may the  effective  rate of  interest
collected or received by the Holder exceed that which may be charged,  collected
or received by the Holder under applicable law.

                  (e)  Interpretation.  If any term or  provision  of this  Note
shall be held invalid, illegal or unenforceable, the validity of all other terms
and provisions hereof shall in no way be affected thereby.

                  (f)  Successors and Assigns.  This Note shall be binding upon 
the Company and its successors and assigns and shall inure to the benefit of the
Holder and its successors and assigns.

                  (g) Notices. All notices, requests, consents and demands shall
be made in writing and shall be mailed postage prepaid, or delivered by hand, to
the Company or to the Holder  thereof at their  respective  addresses  set forth
below or to such other address as may be furnished in writing to the other party
hereto:

                  If to the Holder:  At the address shown on Schedule A 
                                     attached hereto.

                  with a copy to:       Paramount Capital, Inc.
                                        787 Seventh Avenue
                                        New York, NY 10019
                                        Attn: David R. Walner

                  If to the Company:    Genta Incorporated
                                        3350 General Atomics Court



                                       14

<PAGE>



                                         San Diego, CA 92121
                                         Attention: Chief Executive Officer

                  (h) Saturdays,  Sundays, Holidays. If any date that may at any
time be  specified  in this  Note as a date for the  making  of any  payment  of
principal or interest under this Note shall fall on Saturday, Sunday or on a day
which in New York shall be a legal holiday, then the date for the making of that
payment  shall be the next  subsequent  day which is not a  Saturday,  Sunday or
legal holiday.

                  (i)  Purchase  Agreement.  This Note is  subject  to the terms
contained in the Purchase  Agreement  dated the date hereof  between the Company
and certain  purchasers of the Senior Secured  Convertible  Bridge Notes and the
holder of this Note is entitled to the benefits of such  Purchase  Agreement and
may, in addition to any rights hereunder,  enforce the agreements of the Company
contained  therein and exercise  the remedies  provided for thereby or otherwise
available in respect thereof.




                                       15

<PAGE>


         IN WITNESS  WHEREOF,  this Note has been  executed  and  delivered as a
sealed  instrument  on the date  first  above  written  by the  duly  authorized
representative of the Company.


ATTEST:                                     GENTA INCORPORATED


_______________________             By:     ________________________________
                                            Name:
                                            Its:



(Corporate Seal)




                                       16

<PAGE>


                                    EXHIBIT T
 

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN EXEMPTION  THEREFROM.  ANY SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE
STATE SECURITIES LAWS.



                               GENTA INCORPORATED


            New Class A Bridge Warrant for the Purchase of Shares of
            --------------------------------------------------------
                                  Common Stock
                                  ------------


No. CA-1                                                          350,000 Shares


         FOR VALUE RECEIVED,  GENTA  INCORPORATED.,  a Delaware corporation (the
"COMPANY"),  hereby certifies that THE ARIES DOMESTIC FUND, LP or its registered
assigns (the "Holder") is entitled to purchase from the Company,  subject to the
provisions  of this  Warrant (the  "Warrant"),  at any time on or after the date
hereof (the  "INITIAL  EXERCISE  DATE"),  and prior to 5:00 P.M.,  New York City
time,  on January  27, 2002 (the  "TERMINATION  DATE"),  350,000  fully paid and
non-assessable  shares of the  Common  Stock,  $.001 par value,  of the  Company
("Common Stock"), at an exercise price of $1.50 per share of Common Stock for an
aggregate   exercise  price  of  FIVE  HUNDRED   TWENTY-FIVE   THOUSAND  DOLLARS
($525,000.00)  (the  aggregate  purchase  price  payable for the Warrant  Shares
hereunder  is  hereinafter  sometimes  referred  to as the  "AGGREGATE  EXERCISE
PRICE").  The number of shares of Common Stock to be received  upon  exercise of
this Warrant and the price to be paid for each share of Common Stock are subject
to possible adjustment from time to time as hereinafter set forth. The shares of
Common Stock or other  securities or property  deliverable upon such exercise as
adjusted from time to time is hereinafter  sometimes referred to as the "WARRANT
SHARES." The exercise price of a share of Common Stock in effect at any time and
as adjusted from time to time is hereinafter  sometimes  referred to as the "PER
SHARE EXERCISE  PRICE." The Per Share Exercise Price is subject to adjustment as
hereinafter provided; in the event of any such adjustment, the number of Warrant
Shares shall also be adjusted,  by dividing the Aggregate  Exercise Price by the
Per Share  Exercise  Price in effect  immediately  after  such  adjustment.  The
Aggregate Exercise Price is not subject to adjustment.


<PAGE>

                  1.       EXERCISE OF WARRANT.
                           --------------------

                  (a) This Warrant may be exercised in whole or in part,  at any
time by its holder  commencing  on the  Initial  Exercise  Date and prior to the
Termination  Date, by presentation and surrender of this Warrant,  together with
the duly executed  subscription  form attached at the end hereof, at the address
set forth in subsection  8(a) hereof,  together  with  payment,  by certified or
official bank check or wire transfer payable to the order of the Company, of the
Aggregate Exercise Price or the proportionate part thereof if exercised in part.

                  (b) If this  Warrant is  exercised  in part only,  the Company
shall, upon presentation of this Warrant upon such exercise, execute and deliver
(along with the  certificate  for the Warrant  Shares  purchased)  a new Warrant
evidencing  the  rights of the  Holder  hereof to  purchase  the  balance of the
Warrant  Shares  purchasable  hereunder  upon the same terms and  conditions  as
herein set forth.  Upon proper  exercise of this Warrant,  the Company  promptly
shall deliver certificates for the Warrant Shares to the Holder duly legended as
authorized by the subscription  form. No fractional shares or scrip representing
fractional  shares shall be issued upon exercise of this Warrant;  provided that
the  Company  shall  pay to the  holders  of the  Warrant  cash  in lieu of such
fractional shares.

                  2.  RESERVATION OF WARRANT SHARES;  FULLY PAID SHARES;  TAXES.
The Company hereby  represents that it has, and until expiration of this Warrant
agrees that it shall,  reserve for  issuance or delivery  upon  exercise of this
Warrant,  such  number of shares of the Common  Stock as shall be  required  for
issuance  and/or delivery upon exercise of this Warrant in full, and agrees that
all Warrant Shares so issued and/or delivered will be validly issued, fully paid
and non-assessable,  and further agrees to pay all taxes and charges that may be
imposed upon such issuance and/or delivery.

                  3.       PROTECTION AGAINST DILUTION.
                           ---------------------------

                  (a) In the event the Company  shall,  at any time or from time
to time after the date of issuance of this  Warrant,  issue or distribute to all
of the holders of its shares of Common Stock evidence of its  indebtedness,  any
other securities of the Company or any cash,  property or other assets (any such
event being herein called a "SPECIAL  DIVIDEND"),  the Per Share  Exercise Price
shall be adjusted by multiplying  the Per Share Exercise Price then in effect by
a fraction,  the  numerator of which shall be the then Current  Market Price (as
defined in paragraph  3(k) below) of the Common Stock,  less the Current  Market
Price of the Special  Dividend  issued or distributed in respect of one share of
Common Stock,  and the denominator of which shall be the Current Market Price of
the Common Stock.  Such adjustment  shall be made  successively  whenever such a
record  date  is  fixed.  Such  adjustment  shall  be  made  whenever  any  such
distribution  is made and shall become  effective  immediately  after the record
date  for  the   determination   of   shareholders   entitled  to  receive  such
distribution.

         (b) In case the Company  shall  hereafter  (i) pay a dividend or make a
distribution on its capital stock in shares of Common Stock,  (ii) subdivide its
outstanding


                                        2

<PAGE>

shares of Common  Stock  into a greater  number of  shares,  (iii)  combine  its
outstanding shares of Common Stock into a smaller number of shares or (iv) issue
by  reclassification  of its Common  Stock any  shares of  capital  stock of the
Company,  the Per  Share  Exercise  Price  shall  be  adjusted  to be equal to a
fraction,  the numerator of which shall be the Aggregate  Exercise Price and the
denominator  of which  shall be the  number of  shares of Common  Stock or other
capital stock of the Company  issuable  upon  exercise of this Warrant  assuming
this Warrant had been exercised  immediately prior to such action. An adjustment
made pursuant to this subsection 3(b) shall become effective  immediately  after
the  record  date in the case of a dividend  or  distribution  and shall  become
effective  immediately  after the effective  date in the case of a  subdivision,
combination or reclassification.

                  (c)(i) Except as provided in subsections 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share  (determined  by  dividing  (i) the total  amount,  if any,
received or receivable by the Company in  consideration  of the issuance or sale
of such securities plus the  consideration,  if any, payable to the Company upon
exercise or conversion thereof (collectively, the "TOTAL CONSIDERATION") by (ii)
the number of additional  shares of Common Stock  issued,  sold or issuable upon
exercise or conversion of such  securities)  which is less than the then Current
Market  Price of the Common  Stock (as defined  below) but not below the current
Per Share Exercise Price (which event is governed by subsection  3(c)(ii)),  the
Per Share  Exercise  Price shall be adjusted as of the date of such  issuance or
sale by  multiplying  the Per Share Exercise Price then in effect by a fraction,
the  numerator  of which  shall be (x) the sum of (A) the  number  of  shares of
Common Stock  outstanding  on the record date of such  issuance or sale plus (B)
the Total Consideration divided by the Current Market Price of the Common Stock,
and the  denominator  of which shall be (y) the number of shares of Common Stock
outstanding  on the record date of such issuance or sale plus the maximum number
of additional  shares of Common Stock issued,  sold or issuable upon exercise or
conversion of such securities.

                  (c)(ii) Except as provided in subsection 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share (the "ISSUE PRICE"),  (determined by dividing (i) the Total
Consideration  by (ii) the number of additional  shares of Common Stock issuable
upon  exercise or  conversion  of such  securities)  which is less than the then
current Per Share  Exercise Price in effect on the record date of such issuance,
the Per Share Exercise Price shall be adjusted to equal the Issue Price.

                  (d)  In  the   event   of  any   capital   reorganization   or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or  substantially  as an entirety,  or in
the case of any statutory exchange of securities with another corporation


                                        3

<PAGE>

(including  any  exchange  effected  in  connection  with a  merger  of a  third
corporation  into the Company),  the Holder of this Warrant shall have the right
thereafter  to receive on the  exercise  of this  Warrant the kind and amount of
securities,  cash or other  property  which the Holder  would have owned or have
been   entitled   to   receive    immediately    after   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
had this Warrant been exercised  immediately prior to the effective date of such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or conveyance  and in any such case, if necessary,  appropriate  adjustment
shall be made in the  application  of the provisions set forth in this Section 3
with  respect  to the  rights  and  interests  thereafter  of the Holder of this
Warrant  to the end that  the  provisions  set  forth  in this  Section  3 shall
thereafter  correspondingly be made applicable,  as nearly as may reasonably be,
in relation to any shares of stock or other  securities  or property  thereafter
deliverable  on the  exercise  of this  Warrant.  The above  provisions  of this
subsection   3(e)  shall   similarly   apply  to   successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The issuer of any shares of stock or other  securities or property
thereafter  deliverable on the exercise of this Warrant shall be responsible for
all of the agreements and  obligations of the Company  hereunder.  Notice of any
such  reorganization,   reclassification,   consolidation,   merger,   statutory
exchange,  sale or  conveyance  and of said  provisions  so proposed to be made,
shall be mailed to the  Holders of the  Warrants  not less than 30 days prior to
such event. A sale of all or substantially  all of the assets of the Company for
a  consideration   consisting   primarily  of  securities   shall  be  deemed  a
consolidation or merger for the foregoing purposes.

                  (e) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (f)  Whenever  the  Per  Share  Exercise  Price  payable  upon
exercise of each  Warrant is adjusted  pursuant to this Section 3, the number of
shares of Common Stock underlying a Warrant shall  simultaneously be adjusted to
equal the number  obtained  by  dividing  the  Aggregate  Exercise  Price by the
adjusted Per Share Exercise Price.

                  (g) No  adjustment  in the Per Share  Exercise  Price shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.01 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  subsection  3(g) are not  required  to be made shall be
carried  forward  and taken  into  account  in any  subsequent  adjustment.  All
calculations under this Section 3 shall be made to the nearest


                                        4

<PAGE>

cent or to the nearest  1/100th of a share, as the case may be. Anything in this
Section 3 to the contrary notwithstanding, the Company shall be entitled to make
such  reductions in the Per Share Exercise  Price, in addition to those required
by this Section 3, as it in its  discretion  shall deem to be advisable in order
that any stock  dividend,  subdivision  of shares or  distribution  of rights to
purchase stock or securities  convertible or  exchangeable  for stock  hereafter
made by the Company to its stockholders shall not be taxable.

                  (h)  Whenever  the Per Share  Exercise  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants  in  accordance  with this  Section 3, the  Company  shall  promptly
obtain,  at  its  expense,  a  certificate  of  a  firm  of  independent  public
accountants of recognized  standing  selected by the Board of Directors (who may
be the regular  auditors of the Company)  setting  forth the Per Share  Exercise
Price and the number of Warrant  Shares after such  adjustment  or the effect of
such  modification,  a brief statement of the facts requiring such adjustment or
modification  and the  manner of  computing  the same and  cause  copies of such
certificate to be mailed to the Holders of the Warrants.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 30 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the allocation of the adjusted Per Share Exercise Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  (k) For the purpose of any computation  under Section 3 above,
the then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed,  or if not listed or admitted to trading
on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined by agreement between the Company's Board of Directors,  on the one
part, and the Holders of Warrants  representing the right to purchase a majority
of the Warrant Shares subject to all outstanding  Warrants,  on the second part.
If the Board of


                                        5

<PAGE>

Directors  and such Holders fail to agree on the Current  Market Price within 60
days of the date of the action  giving rise to any  adjustment  pursuant to this
Section 3, such  Holders  shall be  entitled  to  appoint a firm of  independent
public  accountants  or appraisers of recognized  national  standing  reasonably
acceptable  to the  Company,  which shall give their  opinion as to such Current
Market Price on a basis  consistent  with the  essential  intent and  principles
established herein. Upon receipt of such opinion, the Company will promptly mail
a copy  thereof to the  Holder of this  Warrant  and shall make the  adjustments
described therein.  The fees and expenses of such independent public accountants
or appraisers shall be borne by the Company.

                  4.  REGISTRATION  UNDER  SECURITIES ACT OF 1933. The resale of
the Warrant Shares shall be registered on the Shelf  Registration  Statement (as
defined in Article 8 of the Note and Warrant  Purchase  Agreement (the "Purchase
Agreement")  dated as of January 28, 1997,  by and among the Company,  The Aries
Trust,  a Cayman Island Trust,  and The Aries  Domestic  Fund,  L.P., a Delaware
limited partnership) and certain purchasers and the Holder of this Warrant shall
have the registration rights as provided in Article 8 of the Purchase Agreement.
If the Holder is not a party to the Purchase  Agreement,  by  acceptance of this
Warrant the Holder agrees to comply with provisions of Article 8 of the Purchase
Agreement to the same extent as if it were a party thereto.

                  5.  LIMITED  TRANSFERABILITY.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws,
and is so  transferable  only upon the books of the Company which it shall cause
to be maintained for such purpose.  The Company may treat the registered  Holder
of this  Warrant as he or it appears on the  Company's  books at any time as the
Holder for all purposes. The Company shall permit any Holder of a Warrant or his
duly authorized  attorney,  upon written request during ordinary business hours,
to inspect  and copy or make  extracts  from its books  showing  the  registered
holders of Warrants. All Warrants issued upon the transfer or assignment of this
Warrant  will be dated  the same  date as this  Warrant,  and all  rights of the
holder thereof shall be identical to those of the Holder.

                  6.  LOSS,   ETC.,   OF  WARRANT.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                   7. STATUS OF HOLDER.  This  Warrant  does not confer upon the
Holder any right to vote or to consent to or receive  notice as a stockholder of
the Company, as such, in respect of any matters whatsoever,  or any other rights
or liabilities as a stockholder, prior to the exercise hereof.

                   8.  NOTICES.  No  notice or other  communication  under  this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:


                                        6

<PAGE>

                   (a) the  Company  at 3550  General  Atomic  Corporation,  San
         Diego,  California  92121,  Attention:  Thomas H. Adams,  or such other
         address as the Company has designated in writing to the Holder; or

                   (b)  the  Holder  at the  address  indicated  in  the  notice
         provisions  to the  Purchase  Agreement,  or other such  address as the
         Holder has designated in writing to the Company.

                  9. SPECIAL EXERCISE PRICE  ADJUSTMENT.  The Per Share Exercise
Price shall be adjusted at the time of the Final  Closing  Date (as that term is
defined in the Letter  between Genta and Paramount  Capital Inc.,  dated January
28, 1997) if the exercise  price of the Offering  Warrants (as defined below) is
less  than the  exercise  price of the  Warrants.  In such  event  the Per Share
Exercise Price shall be reduced to equal 50% of the then current  exercise price
of the Offering Warrants (as hereafter defined).  "Offering Warrants" shall mean
the  warrants  described  in  paragraph 7 of the Letter  between the Company and
Paramount Capital, Inc. dated January 28, 1997.

                   10. HEADINGS. The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.

                   11.  APPLICABLE  LAW.  This Warrant  shall be governed by and
construed in  accordance  with the law of the State of New York  without  giving
effect to principles of conflicts of law thereof.

                  IN WITNESS  WHEREOF,  Dr.  Robert E.  Klem,  acting for and on
behalf of the  Company,  has  executed  this  Warrant  and caused the  Company's
corporate seal to be hereunto affixed and attested by its Secretary or Assistant
Secretary as of June 23, 1997.


                                             GENTA INCORPORATED



                                             By:      _______________________
                                                      Name:  Dr. Robert E. Klem
                                                      Title: Vice President


ATTEST:



- --------------------------------
Secretary or Assistant Secretary

[Corporate Seal]


                                        7

<PAGE>

                                  SUBSCRIPTION
                                  ------------

         The   undersigned,   ____________________________,   pursuant   to  the
provisions  of the  foregoing  Warrant,  hereby  elects to  exercise  the within
Warrant to the extent of purchasing _____________________ shares of Common Stock
thereunder and hereby makes payment of $_______________ by certified or official
bank check in payment of the exercise price therefor.

Dated:_______________                  Signature:_____________________________

                                       Address:_______________________________


                                   ASSIGNMENT
                                   ----------

         FOR  VALUE  RECEIVED   _______________________________________   hereby
sells,  assigns and  transfers  unto  _____________________________________  the
foregoing  Warrant  and all  rights  evidenced  thereby,  and  does  irrevocably
constitute and appoint _____________________________, attorney, to transfer said
Warrant on the books of Genta, Inc.


Dated:_______________                    Signature:_____________________________

                                         Address:_______________________________


                               PARTIAL ASSIGNMENT
                               ------------------

         FOR  VALUE  RECEIVED   __________________________  hereby  assigns  and
transfers unto _________________________ the right to purchase __________ shares
of the Common  Stock,  no par value per  share,  of Genta,  Inc.  covered by the
foregoing  Warrant,  and a  proportionate  part of said  Warrant  and the rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
__________________________,  attorney,  to transfer that part of said Warrant on
the books of Genta, Inc.


Dated:_______________                      Signature:___________________________

                                           Address:_____________________________


                                        8

<PAGE>


                                    EXHIBIT U

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN EXEMPTION  THEREFROM.  ANY SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE
STATE SECURITIES LAWS.



                               GENTA INCORPORATED


            New Class A Bridge Warrant for the Purchase of Shares of
            --------------------------------------------------------
                                  Common Stock
                                  ------------


No. CA-2                                                       650,000 Shares


                  FOR VALUE RECEIVED, GENTA INCORPORATED., a Delaware
corporation  (the  "COMPANY"),  hereby  certifies  that THE  ARIES  TRUST or its
registered  assigns  (the  "Holder")  is entitled to purchase  from the Company,
subject to the  provisions  of this Warrant (the  "Warrant"),  at any time on or
after the date hereof (the "INITIAL EXERCISE DATE"), and prior to 5:00 P.M., New
York City time, on January 27, 2002 (the "TERMINATION DATE"), 650,000 fully paid
and  non-assessable  shares of the Common Stock, $.001 par value, of the Company
("Common Stock"), at an exercise price of $1.50 per share of Common Stock for an
aggregate  exercise  price  of  NINE  HUNDRED   SEVENTY-FIVE   THOUSAND  DOLLARS
($975,000.00)  (the  aggregate  purchase  price  payable for the Warrant  Shares
hereunder  is  hereinafter  sometimes  referred  to as the  "AGGREGATE  EXERCISE
PRICE").  The number of shares of Common Stock to be received  upon  exercise of
this Warrant and the price to be paid for each share of Common Stock are subject
to possible adjustment from time to time as hereinafter set forth. The shares of
Common Stock or other  securities or property  deliverable upon such exercise as
adjusted from time to time is hereinafter  sometimes referred to as the "WARRANT
SHARES." The exercise price of a share of Common Stock in effect at any time and
as adjusted from time to time is hereinafter  sometimes  referred to as the "PER
SHARE EXERCISE  PRICE." The Per Share Exercise Price is subject to adjustment as
hereinafter provided; in the event of any such adjustment, the number of Warrant
Shares shall also be adjusted,  by dividing the Aggregate  Exercise Price by the
Per Share  Exercise  Price in effect  immediately  after  such  adjustment.  The
Aggregate Exercise Price is not subject to adjustment.


<PAGE>

                  1.       EXERCISE OF WARRANT.
                           --------------------

                  (a) This Warrant may be exercised in whole or in part,  at any
time by its holder  commencing  on the  Initial  Exercise  Date and prior to the
Termination  Date, by presentation and surrender of this Warrant,  together with
the duly executed  subscription  form attached at the end hereof, at the address
set forth in subsection  8(a) hereof,  together  with  payment,  by certified or
official bank check or wire transfer payable to the order of the Company, of the
Aggregate Exercise Price or the proportionate part thereof if exercised in part.

                  (b) If this  Warrant is  exercised  in part only,  the Company
shall, upon presentation of this Warrant upon such exercise, execute and deliver
(along with the  certificate  for the Warrant  Shares  purchased)  a new Warrant
evidencing  the  rights of the  Holder  hereof to  purchase  the  balance of the
Warrant  Shares  purchasable  hereunder  upon the same terms and  conditions  as
herein set forth.  Upon proper  exercise of this Warrant,  the Company  promptly
shall deliver certificates for the Warrant Shares to the Holder duly legended as
authorized by the subscription  form. No fractional shares or scrip representing
fractional  shares shall be issued upon exercise of this Warrant;  provided that
the  Company  shall  pay to the  holders  of the  Warrant  cash  in lieu of such
fractional shares.

                  2.  RESERVATION OF WARRANT SHARES;  FULLY PAID SHARES;  TAXES.
The Company hereby  represents that it has, and until expiration of this Warrant
agrees that it shall,  reserve for  issuance or delivery  upon  exercise of this
Warrant,  such  number of shares of the Common  Stock as shall be  required  for
issuance  and/or delivery upon exercise of this Warrant in full, and agrees that
all Warrant Shares so issued and/or delivered will be validly issued, fully paid
and non-assessable,  and further agrees to pay all taxes and charges that may be
imposed upon such issuance and/or delivery.

                  3.       PROTECTION AGAINST DILUTION.
                           ----------------------------

                  (a) In the event the Company  shall,  at any time or from time
to time after the date of issuance of this  Warrant,  issue or distribute to all
of the holders of its shares of Common Stock evidence of its  indebtedness,  any
other securities of the Company or any cash,  property or other assets (any such
event being herein called a "SPECIAL  DIVIDEND"),  the Per Share  Exercise Price
shall be adjusted by multiplying  the Per Share Exercise Price then in effect by
a fraction,  the  numerator of which shall be the then Current  Market Price (as
defined in paragraph  3(k) below) of the Common Stock,  less the Current  Market
Price of the Special  Dividend  issued or distributed in respect of one share of
Common Stock,  and the denominator of which shall be the Current Market Price of
the Common Stock.  Such adjustment  shall be made  successively  whenever such a
record  date  is  fixed.  Such  adjustment  shall  be  made  whenever  any  such
distribution  is made and shall become  effective  immediately  after the record
date  for  the   determination   of   shareholders   entitled  to  receive  such
distribution.

                  (b) In case the Company shall  hereafter (i) pay a dividend or
make a  distribution  on its  capital  stock in  shares of  Common  Stock,  (ii)
subdivide its outstanding


                                        2

<PAGE>

shares of Common  Stock  into a greater  number of  shares,  (iii)  combine  its
outstanding shares of Common Stock into a smaller number of shares or (iv) issue
by  reclassification  of its Common  Stock any  shares of  capital  stock of the
Company,  the Per  Share  Exercise  Price  shall  be  adjusted  to be equal to a
fraction,  the numerator of which shall be the Aggregate  Exercise Price and the
denominator  of which  shall be the  number of  shares of Common  Stock or other
capital stock of the Company  issuable  upon  exercise of this Warrant  assuming
this Warrant had been exercised  immediately prior to such action. An adjustment
made pursuant to this subsection 3(b) shall become effective  immediately  after
the  record  date in the case of a dividend  or  distribution  and shall  become
effective  immediately  after the effective  date in the case of a  subdivision,
combination or reclassification.

                  (c)(i) Except as provided in subsections 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share  (determined  by  dividing  (i) the total  amount,  if any,
received or receivable by the Company in  consideration  of the issuance or sale
of such securities plus the  consideration,  if any, payable to the Company upon
exercise or conversion thereof (collectively, the "TOTAL CONSIDERATION") by (ii)
the number of additional  shares of Common Stock  issued,  sold or issuable upon
exercise or conversion of such  securities)  which is less than the then Current
Market  Price of the Common  Stock (as defined  below) but not below the current
Per Share Exercise Price (which event is governed by subsection  3(c)(ii)),  the
Per Share  Exercise  Price shall be adjusted as of the date of such  issuance or
sale by  multiplying  the Per Share Exercise Price then in effect by a fraction,
the  numerator  of which  shall be (x) the sum of (A) the  number  of  shares of
Common Stock  outstanding  on the record date of such  issuance or sale plus (B)
the Total Consideration divided by the Current Market Price of the Common Stock,
and the  denominator  of which shall be (y) the number of shares of Common Stock
outstanding  on the record date of such issuance or sale plus the maximum number
of additional  shares of Common Stock issued,  sold or issuable upon exercise or
conversion of such securities.

                  (c)(ii) Except as provided in subsection 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share (the "ISSUE PRICE"),  (determined by dividing (i) the Total
Consideration  by (ii) the number of additional  shares of Common Stock issuable
upon  exercise or  conversion  of such  securities)  which is less than the then
current Per Share  Exercise Price in effect on the record date of such issuance,
the Per Share Exercise Price shall be adjusted to equal the Issue Price.

                  (d)  In  the   event   of  any   capital   reorganization   or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or  substantially  as an entirety,  or in
the case of any statutory exchange of securities with another corporation


                                        3

<PAGE>

(including  any  exchange  effected  in  connection  with a  merger  of a  third
corporation  into the Company),  the Holder of this Warrant shall have the right
thereafter  to receive on the  exercise  of this  Warrant the kind and amount of
securities,  cash or other  property  which the Holder  would have owned or have
been   entitled   to   receive    immediately    after   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
had this Warrant been exercised  immediately prior to the effective date of such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or conveyance  and in any such case, if necessary,  appropriate  adjustment
shall be made in the  application  of the provisions set forth in this Section 3
with  respect  to the  rights  and  interests  thereafter  of the Holder of this
Warrant  to the end that  the  provisions  set  forth  in this  Section  3 shall
thereafter  correspondingly be made applicable,  as nearly as may reasonably be,
in relation to any shares of stock or other  securities  or property  thereafter
deliverable  on the  exercise  of this  Warrant.  The above  provisions  of this
subsection   3(e)  shall   similarly   apply  to   successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The issuer of any shares of stock or other  securities or property
thereafter  deliverable on the exercise of this Warrant shall be responsible for
all of the agreements and  obligations of the Company  hereunder.  Notice of any
such  reorganization,   reclassification,   consolidation,   merger,   statutory
exchange,  sale or  conveyance  and of said  provisions  so proposed to be made,
shall be mailed to the  Holders of the  Warrants  not less than 30 days prior to
such event. A sale of all or substantially  all of the assets of the Company for
a  consideration   consisting   primarily  of  securities   shall  be  deemed  a
consolidation or merger for the foregoing purposes.

                  (e) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (f)  Whenever  the  Per  Share  Exercise  Price  payable  upon
exercise of each  Warrant is adjusted  pursuant to this Section 3, the number of
shares of Common Stock underlying a Warrant shall  simultaneously be adjusted to
equal the number  obtained  by  dividing  the  Aggregate  Exercise  Price by the
adjusted Per Share Exercise Price.

                  (g) No  adjustment  in the Per Share  Exercise  Price shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.01 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  subsection  3(g) are not  required  to be made shall be
carried  forward  and taken  into  account  in any  subsequent  adjustment.  All
calculations under this Section 3 shall be made to the nearest


                                       4

<PAGE>

cent or to the nearest  1/100th of a share, as the case may be. Anything in this
Section 3 to the contrary notwithstanding, the Company shall be entitled to make
such  reductions in the Per Share Exercise  Price, in addition to those required
by this Section 3, as it in its  discretion  shall deem to be advisable in order
that any stock  dividend,  subdivision  of shares or  distribution  of rights to
purchase stock or securities  convertible or  exchangeable  for stock  hereafter
made by the Company to its stockholders shall not be taxable.

                  (h)  Whenever  the Per Share  Exercise  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants  in  accordance  with this  Section 3, the  Company  shall  promptly
obtain,  at  its  expense,  a  certificate  of  a  firm  of  independent  public
accountants of recognized  standing  selected by the Board of Directors (who may
be the regular  auditors of the Company)  setting  forth the Per Share  Exercise
Price and the number of Warrant  Shares after such  adjustment  or the effect of
such  modification,  a brief statement of the facts requiring such adjustment or
modification  and the  manner of  computing  the same and  cause  copies of such
certificate to be mailed to the Holders of the Warrants.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 30 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the allocation of the adjusted Per Share Exercise Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  (k) For the purpose of any computation  under Section 3 above,
the then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed,  or if not listed or admitted to trading
on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined by agreement between the Company's Board of Directors,  on the one
part, and the Holders of Warrants  representing the right to purchase a majority
of the Warrant Shares subject to all outstanding  Warrants,  on the second part.
If the Board of


                                        5

<PAGE>

Directors  and such Holders fail to agree on the Current  Market Price within 60
days of the date of the action  giving rise to any  adjustment  pursuant to this
Section 3, such  Holders  shall be  entitled  to  appoint a firm of  independent
public  accountants  or appraisers of recognized  national  standing  reasonably
acceptable  to the  Company,  which shall give their  opinion as to such Current
Market Price on a basis  consistent  with the  essential  intent and  principles
established herein. Upon receipt of such opinion, the Company will promptly mail
a copy  thereof to the  Holder of this  Warrant  and shall make the  adjustments
described therein.  The fees and expenses of such independent public accountants
or appraisers shall be borne by the Company.

                  4.  REGISTRATION  UNDER  SECURITIES ACT OF 1933. The resale of
the Warrant Shares shall be registered on the Shelf  Registration  Statement (as
defined in Article 8 of the Note and Warrant  Purchase  Agreement (the "Purchase
Agreement")  dated as of January 28, 1997,  by and among the Company,  The Aries
Fund, a Cayman  Island  Trust,  and The Aries  Domestic  Fund,  L.P., a Delaware
limited partnership) and certain purchasers and the Holder of this Warrant shall
have the registration rights as provided in Article 8 of the Purchase Agreement.
If the Holder is not a party to the Purchase  Agreement,  by  acceptance of this
Warrant the Holder agrees to comply with provisions of Article 8 of the Purchase
Agreement to the same extent as if it were a party thereto.

                  5.  LIMITED  TRANSFERABILITY.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws,
and is so  transferable  only upon the books of the Company which it shall cause
to be maintained for such purpose.  The Company may treat the registered  Holder
of this  Warrant as he or it appears on the  Company's  books at any time as the
Holder for all purposes. The Company shall permit any Holder of a Warrant or his
duly authorized  attorney,  upon written request during ordinary business hours,
to inspect  and copy or make  extracts  from its books  showing  the  registered
holders of Warrants. All Warrants issued upon the transfer or assignment of this
Warrant  will be dated  the same  date as this  Warrant,  and all  rights of the
holder thereof shall be identical to those of the Holder.

                  6.  LOSS,   ETC.,   OF  WARRANT.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  7.  STATUS OF HOLDER.  This  Warrant  does not confer upon the
Holder any right to vote or to consent to or receive  notice as a stockholder of
the Company, as such, in respect of any matters whatsoever,  or any other rights
or liabilities as a stockholder, prior to the exercise hereof.

                  8.  NOTICES.  No  notice  or other  communication  under  this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:


                                        6

<PAGE>

                  (a) the Company at 3550 General Atomic Corporation, San Diego,
California  92121,  Attention:  Thomas H.  Adams,  or such other  address as the
Company has designated in writing to the Holder; or

                  (b)  the  Holder  at  the  address  indicated  in  the  notice
         provisions  to the  Purchase  Agreement,  or other such  address as the
         Holder has designated in writing to the Company.

                  9. SPECIAL EXERCISE PRICE  ADJUSTMENT.  The Per Share Exercise
Price shall be adjusted at the time of the Final  Closing  Date (as that term is
defined in the Letter  between Genta and Paramount  Capital Inc.,  dated January
28, 1997) if the exercise  price of the Offering  Warrants (as defined below) is
less  than the  exercise  price of the  Warrants.  In such  event  the Per Share
Exercise Price shall be reduced to equal 50% of the then current  exercise price
of the Offering Warrants (as hereafter defined).  "Offering Warrants" shall mean
the  warrants  described  in  paragraph 7 of the Letter  between the Company and
Paramount Capital, Inc. dated January 28, 1997.

                  10. HEADINGS.  The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.

                  11.  APPLICABLE  LAW.  This  Warrant  shall be governed by and
construed in  accordance  with the law of the State of New York  without  giving
effect to principles of conflicts of law thereof.

                  IN WITNESS  WHEREOF,  Dr.  Robert E.  Klem,  acting for and on
behalf of the  Company,  has  executed  this  Warrant  and caused the  Company's
corporate seal to be hereunto affixed and attested by its Secretary or Assistant
Secretary as of June 23, 1997.


                                        GENTA INCORPORATED


                                         By:  _______________________
                                                 Name:  Dr. Robert E. Klem
                                                 Title: Vice President


ATTEST:



- -------------------------
Secretary or Assistant Secretary

[Corporate Seal]


                                        7

<PAGE>


                                  SUBSCRIPTION
                                  ------------

                  The undersigned, ____________________________, pursuant to the
provisions  of the  foregoing  Warrant,  hereby  elects to  exercise  the within
Warrant to the extent of purchasing _____________________ shares of Common Stock
thereunder and hereby makes payment of $_______________ by certified or official
bank check in payment of the exercise price therefor.

Dated:_______________                   Signature:_____________________________

                                        Address:_______________________________


                                   ASSIGNMENT
                                   ----------

                  FOR  VALUE  RECEIVED   _______________________________________
hereby sells,  assigns and transfers unto  _____________________________________
the foregoing  Warrant and all rights  evidenced  thereby,  and does irrevocably
constitute and appoint _____________________________, attorney, to transfer said
Warrant on the books of Genta, Inc.


Dated:_______________                   Signature:_____________________________

                                         Address:______________________________


                               PARTIAL ASSIGNMENT
                               ------------------

                  FOR VALUE RECEIVED  __________________________  hereby assigns
and transfers unto  _________________________  the right to purchase  __________
shares of the Common Stock,  no par value per share, of Genta,  Inc.  covered by
the foregoing  Warrant,  and a proportionate part of said Warrant and the rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
__________________________,  attorney,  to transfer that part of said Warrant on
the books of Genta, Inc.


Dated:_______________                   Signature:___________________________

                                        Address:_____________________________


                                        8


<PAGE>

                                    EXHIBIT V

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN EXEMPTION  THEREFROM.  ANY SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE
STATE SECURITIES LAWS.


                               GENTA INCORPORATED

            New Class B Bridge Warrant for the Purchase of Shares of
            --------------------------------------------------------
                                  Common Stock
                                  ------------

No. CB-1                                                          350,000 Shares

                  FOR  VALUE   RECEIVED,   GENTA   INCORPORATED.,   a   Delaware
corporation (the  "COMPANY"),  hereby certifies that THE ARIES DOMESTIC FUND, LP
or its  registered  assigns  (the  "Holder")  is entitled  to purchase  from the
Company, subject to the provisions of this Warrant (the "Warrant"),  at any time
on or after the date hereof (the  "INITIAL  EXERCISE  DATE"),  and prior to 5:00
P.M., New York City time, on January 27, 2002 (the "TERMINATION DATE"),  350,000
fully paid and  non-assessable  shares of the Common Stock,  $.001 par value, of
the Company ("Common Stock"),  at an exercise price of $1.50 per share of Common
Stock for an  aggregate  exercise  price of FIVE  HUNDRED  TWENTY-FIVE  THOUSAND
DOLLARS  ($525,000.00)  (the  aggregate  purchase  price payable for the Warrant
Shares hereunder is hereinafter sometimes referred to as the "AGGREGATE EXERCISE
PRICE").  The number of shares of Common Stock to be received  upon  exercise of
this Warrant and the price to be paid for each share of Common Stock are subject
to possible adjustment from time to time as hereinafter set forth. The shares of
Common Stock or other  securities or property  deliverable upon such exercise as
adjusted from time to time is hereinafter  sometimes referred to as the "WARRANT
SHARES." The exercise price of a share of Common Stock in effect at any time and
as adjusted from time to time is hereinafter  sometimes  referred to as the "PER
SHARE EXERCISE  PRICE." The Per Share Exercise Price is subject to adjustment as
hereinafter provided; in the event of any such adjustment, the number of Warrant
Shares shall also be adjusted,  by dividing the Aggregate  Exercise Price by the
Per Share  Exercise  Price in effect  immediately  after  such  adjustment.  The
Aggregate Exercise Price is not subject to adjustment.


<PAGE>

                  1.       EXERCISE OF WARRANT.

                  (a) This Warrant may be exercised in whole or in part,  at any
time by its holder  commencing  on the  Initial  Exercise  Date and prior to the
Termination  Date, by presentation and surrender of this Warrant,  together with
the duly executed  subscription  form attached at the end hereof, at the address
set forth in subsection  8(a) hereof,  together  with  payment,  by certified or
official bank check or wire transfer payable to the order of the Company, of the
Aggregate Exercise Price or the proportionate part thereof if exercised in part.

                  (b) If this  Warrant is  exercised  in part only,  the Company
shall, upon presentation of this Warrant upon such exercise, execute and deliver
(along with the  certificate  for the Warrant  Shares  purchased)  a new Warrant
evidencing  the  rights of the  Holder  hereof to  purchase  the  balance of the
Warrant  Shares  purchasable  hereunder  upon the same terms and  conditions  as
herein set forth.  Upon proper  exercise of this Warrant,  the Company  promptly
shall deliver certificates for the Warrant Shares to the Holder duly legended as
authorized by the subscription  form. No fractional shares or scrip representing
fractional  shares shall be issued upon exercise of this Warrant;  provided that
the  Company  shall  pay to the  holders  of the  Warrant  cash  in lieu of such
fractional shares.

                  2.  RESERVATION OF WARRANT SHARES;  FULLY PAID SHARES;  TAXES.
The Company hereby  represents that it has, and until expiration of this Warrant
agrees that it shall,  reserve for  issuance or delivery  upon  exercise of this
Warrant,  such  number of shares of the Common  Stock as shall be  required  for
issuance  and/or delivery upon exercise of this Warrant in full, and agrees that
all Warrant Shares so issued and/or delivered will be validly issued, fully paid
and non-assessable,  and further agrees to pay all taxes and charges that may be
imposed upon such issuance and/or delivery.

                  3.       PROTECTION AGAINST DILUTION.

                  (a) In the event the Company  shall,  at any time or from time
to time after the date of issuance of this  Warrant,  issue or distribute to all
of the holders of its shares of Common Stock evidence of its  indebtedness,  any
other securities of the Company or any cash,  property or other assets (any such
event being herein called a "SPECIAL  DIVIDEND"),  the Per Share  Exercise Price
shall be adjusted by multiplying  the Per Share Exercise Price then in effect by
a fraction,  the  numerator of which shall be the then Current  Market Price (as
defined in paragraph  3(k) below) of the Common Stock,  less the Current  Market
Price of the Special  Dividend  issued or distributed in respect of one share of
Common Stock,  and the denominator of which shall be the Current Market Price of
the Common Stock.  Such adjustment  shall be made  successively  whenever such a
record  date  is  fixed.  Such  adjustment  shall  be  made  whenever  any  such
distribution  is made and shall become  effective  immediately  after the record
date  for  the   determination   of   shareholders   entitled  to  receive  such
distribution.

                  (b) In case the Company shall  hereafter (i) pay a dividend or
make a  distribution  on its  capital  stock in  shares of  Common  Stock,  (ii)
subdivide its outstanding


                                        2

<PAGE>

shares of Common  Stock  into a greater  number of  shares,  (iii)  combine  its
outstanding shares of Common Stock into a smaller number of shares or (iv) issue
by  reclassification  of its Common  Stock any  shares of  capital  stock of the
Company,  the Per  Share  Exercise  Price  shall  be  adjusted  to be equal to a
fraction,  the numerator of which shall be the Aggregate  Exercise Price and the
denominator  of which  shall be the  number of  shares of Common  Stock or other
capital stock of the Company  issuable  upon  exercise of this Warrant  assuming
this Warrant had been exercised  immediately prior to such action. An adjustment
made pursuant to this subsection 3(b) shall become effective  immediately  after
the  record  date in the case of a dividend  or  distribution  and shall  become
effective  immediately  after the effective  date in the case of a  subdivision,
combination or reclassification.

                  (c)(i) Except as provided in subsections 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share  (determined  by  dividing  (i) the total  amount,  if any,
received or receivable by the Company in  consideration  of the issuance or sale
of such securities plus the  consideration,  if any, payable to the Company upon
exercise or conversion thereof (collectively, the "TOTAL CONSIDERATION") by (ii)
the number of additional  shares of Common Stock  issued,  sold or issuable upon
exercise or conversion of such  securities)  which is less than the then Current
Market  Price of the Common  Stock (as defined  below) but not below the current
Per Share Exercise Price (which event is governed by subsection  3(c)(ii)),  the
Per Share  Exercise  Price shall be adjusted as of the date of such  issuance or
sale by  multiplying  the Per Share Exercise Price then in effect by a fraction,
the  numerator  of which  shall be (x) the sum of (A) the  number  of  shares of
Common Stock  outstanding  on the record date of such  issuance or sale plus (B)
the Total Consideration divided by the Current Market Price of the Common Stock,
and the  denominator  of which shall be (y) the number of shares of Common Stock
outstanding  on the record date of such issuance or sale plus the maximum number
of additional  shares of Common Stock issued,  sold or issuable upon exercise or
conversion of such securities.

                  (c)(ii) Except as provided in subsection 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share (the "ISSUE PRICE"),  (determined by dividing (i) the Total
Consideration  by (ii) the number of additional  shares of Common Stock issuable
upon  exercise or  conversion  of such  securities)  which is less than the then
current Per Share  Exercise Price in effect on the record date of such issuance,
the Per Share Exercise Price shall be adjusted to equal the Issue Price.

                  (d)  In  the   event   of  any   capital   reorganization   or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or  substantially  as an entirety,  or in
the case of any statutory exchange of securities with another corporation


                                        3

<PAGE>

(including  any  exchange  effected  in  connection  with a  merger  of a  third
corporation  into the Company),  the Holder of this Warrant shall have the right
thereafter  to receive on the  exercise  of this  Warrant the kind and amount of
securities,  cash or other  property  which the Holder  would have owned or have
been   entitled   to   receive    immediately    after   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
had this Warrant been exercised  immediately prior to the effective date of such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or conveyance  and in any such case, if necessary,  appropriate  adjustment
shall be made in the  application  of the provisions set forth in this Section 3
with  respect  to the  rights  and  interests  thereafter  of the Holder of this
Warrant  to the end that  the  provisions  set  forth  in this  Section  3 shall
thereafter  correspondingly be made applicable,  as nearly as may reasonably be,
in relation to any shares of stock or other  securities  or property  thereafter
deliverable  on the  exercise  of this  Warrant.  The above  provisions  of this
subsection   3(e)  shall   similarly   apply  to   successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The issuer of any shares of stock or other  securities or property
thereafter  deliverable on the exercise of this Warrant shall be responsible for
all of the agreements and  obligations of the Company  hereunder.  Notice of any
such  reorganization,   reclassification,   consolidation,   merger,   statutory
exchange,  sale or  conveyance  and of said  provisions  so proposed to be made,
shall be mailed to the  Holders of the  Warrants  not less than 30 days prior to
such event. A sale of all or substantially  all of the assets of the Company for
a  consideration   consisting   primarily  of  securities   shall  be  deemed  a
consolidation or merger for the foregoing purposes.

                  (e) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (f)  Whenever  the  Per  Share  Exercise  Price  payable  upon
exercise of each  Warrant is adjusted  pursuant to this Section 3, the number of
shares of Common Stock underlying a Warrant shall  simultaneously be adjusted to
equal the number  obtained  by  dividing  the  Aggregate  Exercise  Price by the
adjusted Per Share Exercise Price.

                  (g) No  adjustment  in the Per Share  Exercise  Price shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.01 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  subsection  3(g) are not  required  to be made shall be
carried  forward  and taken  into  account  in any  subsequent  adjustment.  All
calculations under this Section 3 shall be made to the nearest


                                        4

<PAGE>

cent or to the nearest  1/100th of a share, as the case may be. Anything in this
Section 3 to the contrary notwithstanding, the Company shall be entitled to make
such  reductions in the Per Share Exercise  Price, in addition to those required
by this Section 3, as it in its  discretion  shall deem to be advisable in order
that any stock  dividend,  subdivision  of shares or  distribution  of rights to
purchase stock or securities  convertible or  exchangeable  for stock  hereafter
made by the Company to its stockholders shall not be taxable.

                  (h)  Whenever  the Per Share  Exercise  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants  in  accordance  with this  Section 3, the  Company  shall  promptly
obtain,  at  its  expense,  a  certificate  of  a  firm  of  independent  public
accountants of recognized  standing  selected by the Board of Directors (who may
be the regular  auditors of the Company)  setting  forth the Per Share  Exercise
Price and the number of Warrant  Shares after such  adjustment  or the effect of
such  modification,  a brief statement of the facts requiring such adjustment or
modification  and the  manner of  computing  the same and  cause  copies of such
certificate to be mailed to the Holders of the Warrants.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 30 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the allocation of the adjusted Per Share Exercise Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  (k) For the purpose of any computation  under Section 3 above,
the then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed,  or if not listed or admitted to trading
on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined by agreement between the Company's Board of Directors,  on the one
part, and the Holders of Warrants  representing the right to purchase a majority
of the Warrant Shares subject to all outstanding  Warrants,  on the second part.
If the Board of


                                        5

<PAGE>

Directors  and such Holders fail to agree on the Current  Market Price within 60
days of the date of the action  giving rise to any  adjustment  pursuant to this
Section 3, such  Holders  shall be  entitled  to  appoint a firm of  independent
public  accountants  or appraisers of recognized  national  standing  reasonably
acceptable  to the  Company,  which shall give their  opinion as to such Current
Market Price on a basis  consistent  with the  essential  intent and  principles
established herein. Upon receipt of such opinion, the Company will promptly mail
a copy  thereof to the  Holder of this  Warrant  and shall make the  adjustments
described therein.  The fees and expenses of such independent public accountants
or appraisers shall be borne by the Company.

                  4.  REGISTRATION  UNDER  SECURITIES ACT OF 1933. The resale of
the Warrant Shares shall be registered on the Shelf  Registration  Statement (as
defined in Article 8 of the Note and Warrant  Purchase  Agreement (the "Purchase
Agreement")  dated as of January 28, 1997,  by and among the Company,  The Aries
Fund, a Cayman  Island  Trust,  and The Aries  Domestic  Fund,  L.P., a Delaware
limited partnership) and certain purchasers and the Holder of this Warrant shall
have the registration rights as provided in Article 8 of the Purchase Agreement.
If the Holder is not a party to the Purchase  Agreement,  by  acceptance of this
Warrant the Holder agrees to comply with provisions of Article 8 of the Purchase
Agreement to the same extent as if it were a party thereto.

                  5.  LIMITED  TRANSFERABILITY.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws,
and is so  transferable  only upon the books of the Company which it shall cause
to be maintained for such purpose.  The Company may treat the registered  Holder
of this  Warrant as he or it appears on the  Company's  books at any time as the
Holder for all purposes. The Company shall permit any Holder of a Warrant or his
duly authorized  attorney,  upon written request during ordinary business hours,
to inspect  and copy or make  extracts  from its books  showing  the  registered
holders of Warrants. All Warrants issued upon the transfer or assignment of this
Warrant  will be dated  the same  date as this  Warrant,  and all  rights of the
holder thereof shall be identical to those of the Holder.

                  6.  LOSS,   ETC.,   OF  WARRANT.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  7.  STATUS OF HOLDER.  This  Warrant  does not confer upon the
Holder any right to vote or to consent to or receive  notice as a stockholder of
the Company, as such, in respect of any matters whatsoever,  or any other rights
or liabilities as a stockholder, prior to the exercise hereof.

                  8.  NOTICES.  No  notice  or other  communication  under  this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:


                                        6

<PAGE>

                  (a) the Company at 3550 General Atomic Corporation, San Diego,
         California 92121, Attention:  Thomas H. Adams, or such other address as
         the Company has designated in writing to the Holder; or

                  (b)  the  Holder  at  the  address  indicated  in  the  notice
         provisions  to the  Purchase  Agreement,  or other such  address as the
         Holder has designated in writing to the Company.

                  9. SPECIAL EXERCISE PRICE  ADJUSTMENT.  The Per Share Exercise
Price shall be adjusted at the time of the Final  Closing  Date (as that term is
defined in the Letter  between Genta and Paramount  Capital Inc.,  dated January
28, 1997) if the exercise  price of the Offering  Warrants (as defined below) is
less  than the  exercise  price of the  Warrants.  In such  event  the Per Share
Exercise Price shall be reduced to equal 50% of the then current  exercise price
of the Offering Warrants (as hereafter defined).  "Offering Warrants" shall mean
the  warrants  described  in  paragraph 7 of the Letter  between the Company and
Paramount Capital, Inc. dated January 28, 1997.

                  10. HEADINGS.  The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.

                  11.  APPLICABLE  LAW.  This  Warrant  shall be governed by and
construed in  accordance  with the law of the State of New York  without  giving
effect to principles of conflicts of law thereof.

                  IN WITNESS  WHEREOF,  Dr.  Robert E.  Klem,  acting for and on
behalf of the  Company,  has  executed  this  Warrant  and caused the  Company's
corporate seal to be hereunto affixed and attested by its Secretary or Assistant
Secretary as of June 23, 1997.


                                              GENTA INCORPORATED



                                              By: _____________________
                                                       Name:  Dr. Robert E. Klem
                                                       Title: Vice President


ATTEST:



- -------------------------
Secretary or Assistant Secretary

[Corporate Seal]


                                        7

<PAGE>


                                  SUBSCRIPTION
                                  ------------

                  The undersigned, ____________________________, pursuant to the
provisions  of the  foregoing  Warrant,  hereby  elects to  exercise  the within
Warrant to the extent of purchasing _____________________ shares of Common Stock
thereunder and hereby makes payment of $_______________ by certified or official
bank check in payment of the exercise price therefor.

Dated:_______________                  Signature:_____________________________

                                       Address:_______________________________


                                   ASSIGNMENT
                                   ----------

                  FOR  VALUE  RECEIVED   _______________________________________
hereby sells,  assigns and transfers unto  _____________________________________
the foregoing  Warrant and all rights  evidenced  thereby,  and does irrevocably
constitute and appoint _____________________________, attorney, to transfer said
Warrant on the books of Genta, Inc.


Dated:_______________                  Signature:_____________________________

                                       Address:______________________________


                               PARTIAL ASSIGNMENT
                               ------------------

                  FOR VALUE RECEIVED  __________________________  hereby assigns
and transfers unto  _________________________  the right to purchase  __________
shares of the Common Stock,  no par value per share, of Genta,  Inc.  covered by
the foregoing  Warrant,  and a proportionate part of said Warrant and the rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
__________________________,  attorney,  to transfer that part of said Warrant on
the books of Genta, Inc.


Dated:_______________                  Signature:___________________________

                                       Address:_____________________________




                                        8


<PAGE>

                                    EXHIBIT W

THESE  SECURITIES HAVE NOT BEEN  REGISTERED  UNDER THE SECURITIES ACT OF 1933 OR
ANY APPLICABLE STATE  SECURITIES  LAWS. THEY MAY NOT BE SOLD,  OFFERED FOR SALE,
PLEDGED  OR  HYPOTHECATED   OR  OTHERWISE   TRANSFERRED  IN  THE  ABSENCE  OF  A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN EXEMPTION  THEREFROM.  ANY SUCH TRANSFER MAY ALSO BE SUBJECT TO APPLICABLE
STATE SECURITIES LAWS.



                               GENTA INCORPORATED


            New Class B Bridge Warrant for the Purchase of Shares of
            --------------------------------------------------------
                                  Common Stock
                                  ------------

No. CB-2                                                          650,000 Shares


                  FOR VALUE RECEIVED, GENTA INCORPORATED., a Delaware
corporation  (the  "COMPANY"),  hereby  certifies  that THE  ARIES  TRUST or its
registered  assigns  (the  "Holder")  is entitled to purchase  from the Company,
subject to the  provisions  of this Warrant (the  "Warrant"),  at any time on or
after the date hereof (the "INITIAL EXERCISE DATE"), and prior to 5:00 P.M., New
York City time, on January 27, 2002 (the "TERMINATION DATE"), 650,000 fully paid
and  non-assessable  shares of the Common Stock, $.001 par value, of the Company
("Common Stock"), at an exercise price of $1.50 per share of Common Stock for an
aggregate  exercise  price  of  NINE  HUNDRED   SEVENTY-FIVE   THOUSAND  DOLLARS
($975,000.00)  (the  aggregate  purchase  price  payable for the Warrant  Shares
hereunder  is  hereinafter  sometimes  referred  to as the  "AGGREGATE  EXERCISE
PRICE").  The number of shares of Common Stock to be received  upon  exercise of
this Warrant and the price to be paid for each share of Common Stock are subject
to possible adjustment from time to time as hereinafter set forth. The shares of
Common Stock or other  securities or property  deliverable upon such exercise as
adjusted from time to time is hereinafter  sometimes referred to as the "WARRANT
SHARES." The exercise price of a share of Common Stock in effect at any time and
as adjusted from time to time is hereinafter  sometimes  referred to as the "PER
SHARE EXERCISE  PRICE." The Per Share Exercise Price is subject to adjustment as
hereinafter provided; in the event of any such adjustment, the number of Warrant
Shares shall also be adjusted,  by dividing the Aggregate  Exercise Price by the
Per Share  Exercise  Price in effect  immediately  after  such  adjustment.  The
Aggregate Exercise Price is not subject to adjustment.


<PAGE>

                  1.       EXERCISE OF WARRANT.
                           --------------------

                  (a) This Warrant may be exercised in whole or in part,  at any
time by its holder  commencing  on the  Initial  Exercise  Date and prior to the
Termination  Date, by presentation and surrender of this Warrant,  together with
the duly executed  subscription  form attached at the end hereof, at the address
set forth in subsection  8(a) hereof,  together  with  payment,  by certified or
official bank check or wire transfer payable to the order of the Company, of the
Aggregate Exercise Price or the proportionate part thereof if exercised in part.

                  (b) If this  Warrant is  exercised  in part only,  the Company
shall, upon presentation of this Warrant upon such exercise, execute and deliver
(along with the  certificate  for the Warrant  Shares  purchased)  a new Warrant
evidencing  the  rights of the  Holder  hereof to  purchase  the  balance of the
Warrant  Shares  purchasable  hereunder  upon the same terms and  conditions  as
herein set forth.  Upon proper  exercise of this Warrant,  the Company  promptly
shall deliver certificates for the Warrant Shares to the Holder duly legended as
authorized by the subscription  form. No fractional shares or scrip representing
fractional  shares shall be issued upon exercise of this Warrant;  provided that
the  Company  shall  pay to the  holders  of the  Warrant  cash  in lieu of such
fractional shares.

                  2.  RESERVATION OF WARRANT SHARES;  FULLY PAID SHARES;  TAXES.
The Company hereby  represents that it has, and until expiration of this Warrant
agrees that it shall,  reserve for  issuance or delivery  upon  exercise of this
Warrant,  such  number of shares of the Common  Stock as shall be  required  for
issuance  and/or delivery upon exercise of this Warrant in full, and agrees that
all Warrant Shares so issued and/or delivered will be validly issued, fully paid
and non-assessable,  and further agrees to pay all taxes and charges that may be
imposed upon such issuance and/or delivery.

                  3.       PROTECTION AGAINST DILUTION.
                           ----------------------------

                  (a) In the event the Company  shall,  at any time or from time
to time after the date of issuance of this  Warrant,  issue or distribute to all
of the holders of its shares of Common Stock evidence of its  indebtedness,  any
other securities of the Company or any cash,  property or other assets (any such
event being herein called a "SPECIAL  DIVIDEND"),  the Per Share  Exercise Price
shall be adjusted by multiplying  the Per Share Exercise Price then in effect by
a fraction,  the  numerator of which shall be the then Current  Market Price (as
defined in paragraph  3(k) below) of the Common Stock,  less the Current  Market
Price of the Special  Dividend  issued or distributed in respect of one share of
Common Stock,  and the denominator of which shall be the Current Market Price of
the Common Stock.  Such adjustment  shall be made  successively  whenever such a
record  date  is  fixed.  Such  adjustment  shall  be  made  whenever  any  such
distribution  is made and shall become  effective  immediately  after the record
date  for  the   determination   of   shareholders   entitled  to  receive  such
distribution.

                  (b) In case the Company shall  hereafter (i) pay a dividend or
make a  distribution  on its  capital  stock in  shares of  Common  Stock,  (ii)
subdivide its outstanding


                                        2

<PAGE>

shares of Common  Stock  into a greater  number of  shares,  (iii)  combine  its
outstanding shares of Common Stock into a smaller number of shares or (iv) issue
by  reclassification  of its Common  Stock any  shares of  capital  stock of the
Company,  the Per  Share  Exercise  Price  shall  be  adjusted  to be equal to a
fraction,  the numerator of which shall be the Aggregate  Exercise Price and the
denominator  of which  shall be the  number of  shares of Common  Stock or other
capital stock of the Company  issuable  upon  exercise of this Warrant  assuming
this Warrant had been exercised  immediately prior to such action. An adjustment
made pursuant to this subsection 3(b) shall become effective  immediately  after
the  record  date in the case of a dividend  or  distribution  and shall  become
effective  immediately  after the effective  date in the case of a  subdivision,
combination or reclassification.

                  (c)(i) Except as provided in subsections 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share  (determined  by  dividing  (i) the total  amount,  if any,
received or receivable by the Company in  consideration  of the issuance or sale
of such securities plus the  consideration,  if any, payable to the Company upon
exercise or conversion thereof (collectively, the "TOTAL CONSIDERATION") by (ii)
the number of additional  shares of Common Stock  issued,  sold or issuable upon
exercise or conversion of such  securities)  which is less than the then Current
Market  Price of the Common  Stock (as defined  below) but not below the current
Per Share Exercise Price (which event is governed by subsection  3(c)(ii)),  the
Per Share  Exercise  Price shall be adjusted as of the date of such  issuance or
sale by  multiplying  the Per Share Exercise Price then in effect by a fraction,
the  numerator  of which  shall be (x) the sum of (A) the  number  of  shares of
Common Stock  outstanding  on the record date of such  issuance or sale plus (B)
the Total Consideration divided by the Current Market Price of the Common Stock,
and the  denominator  of which shall be (y) the number of shares of Common Stock
outstanding  on the record date of such issuance or sale plus the maximum number
of additional  shares of Common Stock issued,  sold or issuable upon exercise or
conversion of such securities.

                  (c)(ii) Except as provided in subsection 3(a) and 3(b)(i),  in
the event the  Company  shall  hereafter  issue or sell any  Common  Stock,  any
securities  convertible into Common Stock or any rights,  options or warrants to
purchase Common Stock or securities  convertible into Common Stock, in each case
for a price per share or entitling the holders  thereof to purchase Common Stock
at a price per share (the "ISSUE PRICE"),  (determined by dividing (i) the Total
Consideration  by (ii) the number of additional  shares of Common Stock issuable
upon  exercise or  conversion  of such  securities)  which is less than the then
current Per Share  Exercise Price in effect on the record date of such issuance,
the Per Share Exercise Price shall be adjusted to equal the Issue Price.

                  (d)  In  the   event   of  any   capital   reorganization   or
reclassification, or any consolidation or merger to which the Company is a party
other than a merger or  consolidation  in which the  Company  is the  continuing
corporation,  or in case of any sale or  conveyance  to  another  entity  of the
property of the Company as an entirety or  substantially  as an entirety,  or in
the case of any statutory exchange of securities with another corporation


                                        3

<PAGE>

(including  any  exchange  effected  in  connection  with a  merger  of a  third
corporation  into the Company),  the Holder of this Warrant shall have the right
thereafter  to receive on the  exercise  of this  Warrant the kind and amount of
securities,  cash or other  property  which the Holder  would have owned or have
been   entitled   to   receive    immediately    after   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
had this Warrant been exercised  immediately prior to the effective date of such
reorganization,  reclassification,  consolidation,  merger,  statutory exchange,
sale or conveyance  and in any such case, if necessary,  appropriate  adjustment
shall be made in the  application  of the provisions set forth in this Section 3
with  respect  to the  rights  and  interests  thereafter  of the Holder of this
Warrant  to the end that  the  provisions  set  forth  in this  Section  3 shall
thereafter  correspondingly be made applicable,  as nearly as may reasonably be,
in relation to any shares of stock or other  securities  or property  thereafter
deliverable  on the  exercise  of this  Warrant.  The above  provisions  of this
subsection   3(e)  shall   similarly   apply  to   successive   reorganizations,
reclassifications,   consolidations,  mergers,  statutory  exchanges,  sales  or
conveyances.  The issuer of any shares of stock or other  securities or property
thereafter  deliverable on the exercise of this Warrant shall be responsible for
all of the agreements and  obligations of the Company  hereunder.  Notice of any
such  reorganization,   reclassification,   consolidation,   merger,   statutory
exchange,  sale or  conveyance  and of said  provisions  so proposed to be made,
shall be mailed to the  Holders of the  Warrants  not less than 30 days prior to
such event. A sale of all or substantially  all of the assets of the Company for
a  consideration   consisting   primarily  of  securities   shall  be  deemed  a
consolidation or merger for the foregoing purposes.

                  (e) In case  any  event  shall  occur as to  which  the  other
provisions  of this  Section 3 are not strictly  applicable  but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by this  Warrant  in  accordance  with  the  essential  intent  and
principles hereof then, in each such case, the Holders of Warrants  representing
the  right  to  purchase  a  majority  of  the  Warrant  Shares  subject  to all
outstanding  Warrants may appoint a firm of  independent  public  accountants of
recognized national standing reasonably  acceptable to the Company,  which shall
give their opinion as to the adjustment,  if any, on a basis consistent with the
essential intent and principles  established  herein,  necessary to preserve the
purchase rights represented by the Warrants.  Upon receipt of such opinion,  the
Company  will  promptly  mail a copy  thereof to the Holder of this  Warrant and
shall make the  adjustments  described  therein.  The fees and  expenses of such
independent public accountants shall be borne by the Company.

                  (f)  Whenever  the  Per  Share  Exercise  Price  payable  upon
exercise of each  Warrant is adjusted  pursuant to this Section 3, the number of
shares of Common Stock underlying a Warrant shall  simultaneously be adjusted to
equal the number  obtained  by  dividing  the  Aggregate  Exercise  Price by the
adjusted Per Share Exercise Price.

                  (g) No  adjustment  in the Per Share  Exercise  Price shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.01 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  subsection  3(g) are not  required  to be made shall be
carried  forward  and taken  into  account  in any  subsequent  adjustment.  All
calculations under this Section 3 shall be made to the nearest


                                        4

<PAGE>

cent or to the nearest  1/100th of a share, as the case may be. Anything in this
Section 3 to the contrary notwithstanding, the Company shall be entitled to make
such  reductions in the Per Share Exercise  Price, in addition to those required
by this Section 3, as it in its  discretion  shall deem to be advisable in order
that any stock  dividend,  subdivision  of shares or  distribution  of rights to
purchase stock or securities  convertible or  exchangeable  for stock  hereafter
made by the Company to its stockholders shall not be taxable.

                  (h)  Whenever  the Per Share  Exercise  Price is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants  in  accordance  with this  Section 3, the  Company  shall  promptly
obtain,  at  its  expense,  a  certificate  of  a  firm  of  independent  public
accountants of recognized  standing  selected by the Board of Directors (who may
be the regular  auditors of the Company)  setting  forth the Per Share  Exercise
Price and the number of Warrant  Shares after such  adjustment  or the effect of
such  modification,  a brief statement of the facts requiring such adjustment or
modification  and the  manner of  computing  the same and  cause  copies of such
certificate to be mailed to the Holders of the Warrants.

                  (i) If the Board of Directors of the Company shall declare any
dividend or other  distribution  with respect to the Common  Stock,  the Company
shall mail notice  thereof to the Holders of the  Warrants not less than 30 days
prior  to the  record  date  fixed  for  determining  stockholders  entitled  to
participate in such dividend or other distribution.

                  (j) If, as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the allocation of the adjusted Per Share Exercise Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  (k) For the purpose of any computation  under Section 3 above,
the then Current  Market Price per share (the "CURRENT  MARKET  PRICE") shall be
deemed to be the last sale price of the Common Stock on the trading day prior to
such date or, in case no such reported sales take place on such day, the average
of the last  reported  bid and asked  prices of the Common Stock on such day, in
either case on the principal  national  securities  exchange on which the Common
Stock is admitted to trading or listed,  or if not listed or admitted to trading
on any such exchange,  the representative  closing bid price of the Common Stock
as reported by the National  Association of Securities  Dealers,  Inc. Automated
Quotations  System  ("NASDAQ"),  or other similar  organization  if NASDAQ is no
longer  reporting such  information,  or, if the Common Stock is not reported on
NASDAQ,   the  high  per  share  bid   price  for  the   Common   Stock  in  the
over-the-counter  market as reported by the National Quotation Bureau or similar
organization,  or if not so available, the fair market value of the Common Stock
as determined by agreement between the Company's Board of Directors,  on the one
part, and the Holders of Warrants  representing the right to purchase a majority
of the Warrant Shares subject to all outstanding  Warrants,  on the second part.
If the Board of


                                        5

<PAGE>

Directors  and such Holders fail to agree on the Current  Market Price within 60
days of the date of the action  giving rise to any  adjustment  pursuant to this
Section 3, such  Holders  shall be  entitled  to  appoint a firm of  independent
public  accountants  or appraisers of recognized  national  standing  reasonably
acceptable  to the  Company,  which shall give their  opinion as to such Current
Market Price on a basis  consistent  with the  essential  intent and  principles
established herein. Upon receipt of such opinion, the Company will promptly mail
a copy  thereof to the  Holder of this  Warrant  and shall make the  adjustments
described therein.  The fees and expenses of such independent public accountants
or appraisers shall be borne by the Company.

                  4.  REGISTRATION  UNDER  SECURITIES ACT OF 1933. The resale of
the Warrant Shares shall be registered on the Shelf  Registration  Statement (as
defined in Article 8 of the Note and Warrant  Purchase  Agreement (the "Purchase
Agreement")  dated as of January 28, 1997,  by and among the Company,  The Aries
Fund, a Cayman  Island  Trust,  and The Aries  Domestic  Fund,  L.P., a Delaware
limited partnership) and certain purchasers and the Holder of this Warrant shall
have the registration rights as provided in Article 8 of the Purchase Agreement.
If the Holder is not a party to the Purchase  Agreement,  by  acceptance of this
Warrant the Holder agrees to comply with provisions of Article 8 of the Purchase
Agreement to the same extent as if it were a party thereto.

                  5.  LIMITED  TRANSFERABILITY.  This  Warrant  may not be sold,
transferred,  assigned or  hypothecated  by the Holder except in compliance with
the provisions of the Act and the applicable  state  securities "blue sky" laws,
and is so  transferable  only upon the books of the Company which it shall cause
to be maintained for such purpose.  The Company may treat the registered  Holder
of this  Warrant as he or it appears on the  Company's  books at any time as the
Holder for all purposes. The Company shall permit any Holder of a Warrant or his
duly authorized  attorney,  upon written request during ordinary business hours,
to inspect  and copy or make  extracts  from its books  showing  the  registered
holders of Warrants. All Warrants issued upon the transfer or assignment of this
Warrant  will be dated  the same  date as this  Warrant,  and all  rights of the
holder thereof shall be identical to those of the Holder.

                  6.  LOSS,   ETC.,   OF  WARRANT.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  7.  STATUS OF HOLDER.  This  Warrant  does not confer upon the
Holder any right to vote or to consent to or receive  notice as a stockholder of
the Company, as such, in respect of any matters whatsoever,  or any other rights
or liabilities as a stockholder, prior to the exercise hereof.

                  8.  NOTICES.  No  notice  or other  communication  under  this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:


                                        6

<PAGE>

                  (a) the Company at 3550 General Atomic Corporation, San Diego,
         California 92121, Attention:  Thomas H. Adams, or such other address as
         the Company has designated in writing to the Holder; or

                  (b)  the  Holder  at  the  address  indicated  in  the  notice
         provisions  to the  Purchase  Agreement,  or other such  address as the
         Holder has designated in writing to the Company.

                  9. SPECIAL EXERCISE PRICE  ADJUSTMENT.  The Per Share Exercise
Price shall be adjusted at the time of the Final  Closing  Date (as that term is
defined in the Letter  between Genta and Paramount  Capital Inc.,  dated January
28, 1997) if the exercise  price of the Offering  Warrants (as defined below) is
less  than the  exercise  price of the  Warrants.  In such  event  the Per Share
Exercise Price shall be reduced to equal 50% of the then current  exercise price
of the Offering Warrants (as hereafter defined).  "Offering Warrants" shall mean
the  warrants  described  in  paragraph 7 of the Letter  between the Company and
Paramount Capital, Inc. dated January 28, 1997.

                  10. HEADINGS.  The headings of this Warrant have been inserted
         as a matter  of  convenience  and  shall not  affect  the  construction
         hereof.

                  11.  APPLICABLE  LAW.  This  Warrant  shall be governed by and
         construed in  accordance  with the law of the State of New York without
         giving effect to principles of conflicts of law thereof.

                  IN WITNESS  WHEREOF,  Dr.  Robert E.  Klem,  acting for and on
behalf of the  Company,  has  executed  this  Warrant  and caused the  Company's
corporate seal to be hereunto affixed and attested by its Secretary or Assistant
Secretary as of June 23, 1997.


                                          GENTA INCORPORATED



                                          By:      _______________________
                                                      Name:  Dr. Robert E. Klem
                                                      Title:    Vice President


ATTEST:



- -------------------------
Secretary or Assistant Secretary

[Corporate Seal]


                                        7

<PAGE>

                                  SUBSCRIPTION
                                  ------------

                  The undersigned, ____________________________, pursuant to the
provisions  of the  foregoing  Warrant,  hereby  elects to  exercise  the within
Warrant to the extent of purchasing _____________________ shares of Common Stock
thereunder and hereby makes payment of $_______________ by certified or official
bank check in payment of the exercise price therefor.

Dated:_______________                  Signature:_____________________________

                                       Address:_______________________________


                                   ASSIGNMENT
                                   ----------

                  FOR  VALUE  RECEIVED   _______________________________________
hereby sells,  assigns and transfers unto  _____________________________________
the foregoing  Warrant and all rights  evidenced  thereby,  and does irrevocably
constitute and appoint _____________________________, attorney, to transfer said
Warrant on the books of Genta, Inc.


Dated:_______________                  Signature:_____________________________

                                       Address:______________________________


                               PARTIAL ASSIGNMENT
                               ------------------

                  FOR VALUE RECEIVED  __________________________  hereby assigns
and transfers unto  _________________________  the right to purchase  __________
shares of the Common Stock,  no par value per share, of Genta,  Inc.  covered by
the foregoing  Warrant,  and a proportionate part of said Warrant and the rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
__________________________,  attorney,  to transfer that part of said Warrant on
the books of Genta, Inc.


Dated:_______________                  Signature:___________________________

                                       Address:_____________________________


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