GENTA INCORPORATED /DE/
PRER14A, 1997-03-07
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                   SCHEDULE A
                                  (Rule a-101)

                     INFORMATION REQUIRED IN PROXY STATEMENT

                             SCHEDULE A INFORMATION
Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. 1)

Filed by the Registrant [x]
Filed by a party other than the Registrant [ ]
Check the appropriate box:
[x]  Preliminary Proxy Statement
[ ]  Confidential, for Use of the Commission Only (as permitted by Rule a-6(e)
     (2))
[ ]  Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to Sec. 240.a-11(c) or Sec. 240.a -12
    

                               Genta Incorporated
                (Name of Registrant as Specified In Its Charter)

                                       N/A
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):
[x]      No fee required

   
[ ]      Fee computed on table below per Exchange Act Rules  a-6(i)(1) and 0-11.
         1) Title of each class of securities to which transaction applies:
    

            ---------------------------------------------------------------

         2) Aggregate number of securities to which transaction applies:

            ---------------------------------------------------------------

         3) Per unit price or other  underlying  value of  transaction  computed
            pursuant to Exchange Act Rule 0-11 (set forth the amount on which 
            the filing fee is calculated and state how it was determined):

            ---------------------------------------------------------------

         4) Proposed maximum aggregate value of transaction:


            ---------------------------------------------------------------


<PAGE>

         5) Total fee paid:

            ---------------------------------------------------------------
[ ]  Fee paid previously with preliminary materials.

[ ]  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2)  and identify the filing for which the  offsetting  fee was paid
     previously.  Identify the previous filing by registration statement number,
     or the Form or Schedule  and the date of its filing.  

     1) Amount Previously Paid:

     ---------------------------------------------------------------

     2) Form, Schedule or Registration Statement No.:

     ---------------------------------------------------------------

     3) Filing Party:

     ---------------------------------------------------------------

     4) Date Filed:

     ---------------------------------------------------------------


<PAGE>

                                 [Company Logo]


                           3550 GENERAL ATOMICS COURT
                               SAN DIEGO, CA 92121
                                 (619) 455-2700

   
                                                                  March 14, 1997
    


Dear Stockholder:

   
         You are cordially  invited to attend the Annual Meeting of Stockholders
which will be held on April 4, 1997, at 11:00 a.m., at the Hyatt  Regency,  3777
La Jolla Village Drive, La Jolla, California.

         The Board of Directors  unanimously  recommends adoption of a proposal,
referred to in The Proxy Statement, which would effectuate a one for ten reverse
stock split of the Company's  outstanding Common Stock. THE NASDAQ STOCK MARKET,
INC. HAS  INDICATED  THAT SHARES OF COMMON STOCK OF THE COMPANY WILL BE DELISTED
FROM THE NASDAQ STOCK MARKET UNLESS THIS  PROPOSAL IS APPROVED BY  STOCKHOLDERS.
SEE "THREAT OF NASDAQ  DELISTING"  ON PAGE 7. YOUR VOTE IS THEREFORE  ESPECIALLY
IMPORTANT.

         The formal notice of the Annual  Meeting and the Proxy  Statement  have
been made a part of this invitation.

         After reading the Proxy Statement,  please mark, date, sign and return,
at an early date,  the  enclosed  proxy in the  prepaid  envelope  addressed  to
ChaseMellon  Shareholder Services, our agent, to ensure that your shares will be
represented.  YOUR SHARES  CANNOT BE VOTED UNLESS YOU SIGN,  DATE AND RETURN THE
ENCLOSED PROXY OR ATTEND THE MEETING IN PERSON.

         A copy of the Company's  Form 10-K for the year ended December 31, 1996
is enclosed.
    

         The Board of Directors and Management look forward to seeing you at the
meeting.

                                                Sincerely yours,



                                                Thomas H. Adams
                                                Chairman of the Board and
                                                Chief Executive Officer


<PAGE>

                               GENTA INCORPORATED
                                  ------------

   
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                            TO BE HELD APRIL 4, 1997
    

                                  ------------

   
         The  Annual  Meeting  of  Stockholders   ("Annual  Meeting")  of  Genta
Incorporated  (the "Company")  will be held at the Hyatt Regency,  3777 La Jolla
Village  Drive,  La Jolla,  California,  on April 4, 1997 at 11:00 a.m., for the
following purposes:

         1.    To  consider  and vote upon a  proposal  to amend  the  Company's
               Certificate of  Incorporation to effectuate a one for ten reverse
               stock split (if approved,  each ten shares of outstanding  Common
               Stock will be  converted  into one share of Common  Stock and the
               conversion  ratios of the  outstanding  shares of Preferred Stock
               will be  commensurately  adjusted)  while reducing the authorized
               number of shares of Common Stock of the Company from  150,000,000
               to 70,000,000.

         2.    To elect one Class III director.

         3.    To ratify  the  selection  of Ernst & Young LLP as the  Company's
               independent auditors.

         4.    To transact  such other  business as may properly come before the
               Annual Meeting and any adjournment of the Annual Meeting.

         The Board of Directors has fixed the close of business on March 4, 1997
as the record date for determining the stockholders entitled to notice of and to
vote at the Annual  Meeting  and any  adjournment  thereof.  A complete  list of
stockholders  entitled to vote will be  available at the  Assistant  Secretary's
office, 3550 General Atomics Court, San Diego,  California,  for ten days before
the meeting.

March 14, 1997                           By Order of the Board of Directors,
    



                                         Thomas H. Adams
                                         Chairman of the Board and
                                         Chief Executive Officer

         IT IS IMPORTANT THAT YOUR SHARES ARE REPRESENTED AT THIS MEETING.  EVEN
IF YOU PLAN TO ATTEND IN PERSON, PLEASE PROMPTLY MARK, DATE, SIGN AND RETURN THE
ENCLOSED PROXY. THIS WILL NOT LIMIT YOUR RIGHT TO ATTEND OR VOTE AT THE MEETING.


<PAGE>



                               GENTA INCORPORATED
   
                           3550 GENERAL ATOMICS COURT
                           SAN DIEGO, CALIFORNIA 92121
                                 (619) 455-2700
    
                                  ------------

                                 PROXY STATEMENT

                                  ------------

   
         This Proxy Statement is furnished in connection  with the  solicitation
by the Board of Directors of Genta  Incorporated,  a Delaware  corporation  (the
"Company"), of proxies in the accompanying form to be used at the Annual Meeting
of Stockholders to be held at the Hyatt Regency, 3777 La Jolla Village Drive, La
Jolla, California,  on April 4, 1997 at 11 a.m. and any adjournment thereof (the
"Annual Meeting"). The shares represented by the proxies received in response to
this  solicitation and not revoked will be voted at the Annual Meeting.  A proxy
may be revoked at any time before it is exercised  by filing with the  Secretary
of the Company a written  revocation  or a duly  executed  proxy bearing a later
date or by voting in person at the Annual Meeting.  On the matters coming before
the Annual  Meeting for which a choice has been  specified by a  stockholder  by
means of the ballot on the proxy,  the shares will be voted  accordingly.  If no
choice is  specified,  the shares will be voted FOR the approval of Proposal One
described in this Proxy Statement, FOR the election of the nominee for Class III
director  listed in this Proxy  Statement and FOR the approval of Proposal Three
described in this Proxy Statement.

         Stockholders  of record of the  Company's  Common  Stock  (the  "Common
Stock")  at the  close of  business  on March 4, 1997 (the  "Record  Date")  are
entitled  to notice  of and to vote at the  Annual  Meeting.  As of the close of
business on the Record Date, the Company had  39,991,626  shares of Common Stock
outstanding and entitled to vote. Each holder of Common Stock is entitled to one
vote for each share held as of the Record  Date.  As of the close of business on
the Record  Date,  the Company also had 528,100  shares of Series A  Convertible
Preferred  Stock (the  "Series A Preferred  Stock") and 1,424 shares of Series C
Convertible  Preferred  Stock ("the Series C Preferred  Stock")  outstanding and
entitled to notice of the Annual  Meeting.  Holders of the Series A and Series C
Preferred Stock are not entitled to vote at the Annual Meeting.

         Proposal  One to be approved  will  require the  affirmative  vote of a
majority of the shares of outstanding  Common Stock.  Directors are elected by a
plurality  vote of shares present in person or represented by proxy and entitled
to vote on the  election  of  directors.  Proposal  Three and any other  matters
submitted for stockholder approval at this Annual Meeting will be decided by the
affirmative  vote of a majority of shares  present in person or  represented  by
proxy and entitled to vote on each such matter.  Abstentions with respect to any
matter are treated as shares present or represented and entitled to vote on that
matter and thus have the same effect as negative  votes.  Broker  non-votes  and
other  circumstances  in which proxy authority has been withheld with respect to
any  matter  are not  deemed  to be  present  or  represented  for  purposes  of
determining whether stockholder approval of that matter has been obtained.

         The entire expense of printing, preparing, assembling and mailing proxy
materials  and the cost of soliciting  proxies will be borne by the Company.  In
addition to the  solicitation  of proxies by mail,  solicitation  may be made by
certain  directors,  officers  and other  employees  of the  Company by personal
interview,  telephone, telegram or facsimile. No additional compensation will be
paid to such  persons  for such  solicitation.  In  addition,  the  Company  has
retained MacKenzie  Partners,  Inc. to assist in the solicitation of proxies for
an  estimated  cost not to exceed  $10,000,  plus  reimbursement  of  reasonable
out-of-pocket  expenses.  MacKenzie  Partners,  Inc.  will solicit  proxies from
individuals,   brokers,   banks,  nominees  and  other  institutional   holders.
Approximately 20 persons will be utilized by MacKenzie  Partners,  Inc. in their
solicitation efforts, which may be made by telephone, facsimile, telegram and in
person.
    

         The  Company  will  reimburse  brokerage  firms  and  others  for their
reasonable expenses in forwarding solicitation materials to beneficial owners of
the Company's Common Stock and Series A and Series C Preferred Stock.

   
         This  Proxy  Statement  and the  accompanying  form of proxy  are being
mailed to stockholders on or about March 14, 1997.
    


<PAGE>

                                    IMPORTANT

   
         PLEASE  MARK,  DATE AND SIGN THE  ENCLOSED  PROXY AND RETURN IT AT YOUR
EARLIEST  CONVENIENCE IN THE ENCLOSED  POSTAGE- PREPAID RETURN ENVELOPE SO THAT,
WHETHER  YOU INTEND TO BE PRESENT AT THE ANNUAL  MEETING OR NOT,  YOUR SHARES OF
COMMON  STOCK CAN BE VOTED.  THIS WILL NOT LIMIT YOUR RIGHT TO ATTEND OR VOTE AT
THE ANNUAL MEETING.
    


                                       -2-


<PAGE>
   
                                  PROPOSAL ONE

   APPROVAL FOR A ONE FOR TEN REVERSE STOCK SPLIT OF THE COMPANY'S OUTSTANDING
  COMMON STOCK AND DECREASE IN THE NUMBER OF AUTHORIZED SHARES OF COMMON STOCK

         The  Company's  Board  of  Directors  has   unanimously   approved  and
recommended  that the  stockholders  of the Company  approve an amendment to the
Company's  Certificate  of  Incorporation,   as  amended  (the  "Certificate  of
Incorporation")  , to effect a one for ten reverse  stock split of the Company's
outstanding Common Stock and to reduce the Company's authorized shares of Common
Stock to  70,000,000  (the  "Reverse  Split  Amendment").  If this  proposal  is
approved,  the Certificate of Incorporation will be amended in the form attached
hereto as Exhibit A.

ADVANTAGES

         Unless the Reverse  Split  Amendment is approved by  stockholders,  the
Nasdaq Stock Market,  Inc.  ("Nasdaq")  has  indicated  that the Company will be
delisted from the Nasdaq Stock Market. See "Threat of Nasdaq Delisting" below.

         The  Board of  Directors  believes  that  such a  delisting  is  likely
adversely to affect the liquidity of the Company's shares and the ability of the
Company to attract  investors.  In addition,  delisting of the Company's  Common
Stock from the Nasdaq SmallCap Market may be deemed to constitute a "Fundamental
Change" under the Company's  Certificate of  Incorporation.  The  Certificate of
Incorporation  currently  provides  that,  upon the occurrence of a "Fundamental
Change," each holder of Series A Preferred Stock has the option of requiring the
Company to repurchase all of such holder's shares of Series A Preferred Stock at
a redemption price of $50 per share plus accrued and unpaid dividends,  an event
that could result in the Company being  required to pay to the holders of Series
A Preferred Stock up to an aggregate of approximately $30,000,000 in cash. Given
the Company's current financial condition and market conditions,  it is unlikely
that the Company  would be able to make such  payment to the holders of Series A
Preferred  Stock and it is therefore  likely that the Company would be forced to
discontinue  operations  or  liquidate  part or all of its  assets  and may seek
protection from creditors under the federal bankruptcy laws.

         The increase in the portion of authorized shares that would be unissued
after the reverse  stock  split (the  "Increased  Available  Portion of Shares")
could be used for any proper  corporate  purpose  approved by the  Company.  The
Increased  Available  Portion  of Shares  will also  provide  the  Company  with
additional  flexibility  to issue  additional  shares in connection  with future
financings.  The Company has entered into a Letter of Intent,  dated January 28,
1997, with Paramount  Capital,  Inc. ("PCI") pursuant to which PCI confirmed its
interest in acting as placement  agent,  on a "best efforts" basis, of a private
placement of Company stock, convertible notes and warrants for proceeds of up to
$7,500,000 (plus an over-allotment  option),  subject to certain  conditions set
forth therein.  Additional  shares could also be used for employee benefit plans
or in connection  with  acquisitions  by the Company.  On February 13, 1997, the
Aries Funds (as  hereinafter  defined)  provided  $3,000,000 in financing to the
Company, arranged by PCI, through the purchase of Bridge Notes and warrants. See
footnote  2 under  the  caption  "Stock  Ownership  of  Management  and  Certain
Beneficial Owners."

DISADVANTAGES

         Because  the  Reverse  Split  Amendment  will  result in the  Increased
Available  Portion of Shares,  it may be  construed  as having an  anti-takeover
effect,  although  neither  the Board of  Directors  nor the  management  of the
Company views this proposal in that perspective.  However, the Company could use
the Increased Available Portion of Shares to frustrate persons seeking to effect
a takeover or otherwise  gain control of the Company by, for example,  privately
placing  shares with  purchasers  who might side with the Board of  Directors in
opposing a hostile  takeover  bid. In  addition,  shares of Common  Stock may be
issued in the event  that the rights  issued in  connection  with the  Company's
Stockholder  Rights  Plan are  exercised.  Shares of Common  Stock could also be
issued to a holder that would thereafter have sufficient  voting power to assure
that any  proposal to amend or repeal the By-Laws or certain  provisions  of the
Certificate of Incorporation  would not receive the requisite vote. Such uses of
the Common  Stock could  render more  difficult,  or  discourage,  an attempt to
acquire control of the Company, if such transaction were opposed by the Board of
Directors.  Further,  the  Increased  Available  Portion of Shares not otherwise
required  to  meet  the  Company's   obligations   under  its   Certificate   of
Incorporation  (including  shares of Common  Stock  which the  Company  could be
required to issue upon an Event of Default under the Bridge Notes) could
    


                                      -3-


<PAGE>
   
be issued by the  Company  without  further  stockholder  approval,  which could
result in further dilution to the holders of Common Stock.

         As of March 5, 1997 there were (i)  39,991,626  shares of Common  Stock
outstanding;  (ii) 528,100 shares of Series A Preferred  Stock,  par value $.001
per share outstanding; (iii) 1,424 shares of Series C Preferred Stock, par value
$.001 per share  outstanding;  (iv) 1,649,302  options  granted and not expired,
cancelled nor exercised;  and (v) warrants granted to purchase 21,557,685 shares
of Common  Stock.  As of March 5,  1997,  pursuant  to the terms of  outstanding
convertible instruments,  options,  warrants and other obligations,  the Company
may be  required  to issue up to  141,546,576  shares  of Common  Stock  plus an
additional  approximately  300,000,000  shares of Common  Stock  which  might be
issuable  upon an Event of Default  under the Bridge  Notes.  As the  conversion
rates and anti-dilution adjustments of some of these convertible instruments are
influenced by the market price of the Company's  Common Stock at any given time,
the  numbers  of  shares  of  Common  Stock  issuable  upon  conversion  of such
instruments  will  be  affected  by  fluctuations  in the  market  price  of the
Company's Common Stock.

REQUIRED VOTE

         In order to be adopted, this proposal must receive the affirmative vote
of the holders of a majority of the outstanding shares of Common Stock.


THREAT OF NASDAQ DELISTING

         Since October 22, 1996 the  Company's  Common Stock has been trading at
less than $1.00 per share. Effective February 7, 1997 the Company's Common Stock
was  removed  from the Nasdaq  National  Market and began  trading on the Nasdaq
SmallCap  Market under a  conditional  exception  from the bid price and capital
surplus  requirements of the Nasdaq SmallCap  Market.  Nasdaq has indicated that
unless the Company's Common Stock achieves a minimum bid price of at least $1.50
per share by April 7, 1997,  and maintains a minimum bid price of at least $1.50
per share for a period of ten consecutive days immediately following the reverse
stock split, the Company's  Common Stock will be delisted.  The Company believes
that,  if the Reverse  Split  Amendment  is  approved,  it can meet these terms;
however,  there can be no assurance that, even with the reverse stock split, the
Company will be able to maintain its listing on the Nasdaq SmallCap  Market.  To
maintain its Nasdaq listing,  the Company will also be required to make a public
filing  with the SEC and  Nasdaq  evidencing  minimum  capital  and  surplus  of
$6,000,000  on or before  April 7,  1997.  There can be no  assurances  that the
Company will succeed in timely  achieving this minimum capital and surplus level
or that even if successful the Company's Common Stock would not be delisted from
the Nasdaq  SmallCap  Market.  There can be no  assurances  that approval of the
Reverse Split  Amendment  will succeed in raising the bid price of the Company's
Common Stock above $1.50 per share, that such minimum price if achieved would be
maintained for the requisite  period, or that even if Nasdaq's minimum bid price
requirement were satisfied the Company's Common Stock would not be delisted from
the Nasdaq SmallCap Market for other reasons.

EXCHANGE OF STOCK CERTIFICATES

         If  the  Reverse   Split   Amendment  is  approved  by  the   Company's
stockholders,  the  Company  will  instruct  its  transfer  agent  to act as its
exchange agent (the "Exchange  Agent") and to act for holders of Common Stock in
implementing the exchange of their certificates.

         Commencing on the effective  date of the Reverse Split  Amendment  (the
"Effective  Date"),  stockholders  will be notified  and  requested to surrender
their certificates  representing shares of Common Stock to the Exchange Agent in
exchange for certificates representing new Common Stock. One share of new Common
Stock will be issued in exchange for each ten presently  issued and  outstanding
shares of Common  Stock.  Beginning  on the  Effective  Date,  each  certificate
representing  shares  of the  Company's  Common  Stock  will be  deemed  for all
corporate purposes to evidence ownership of shares of new Common Stock.

LIQUIDATION OF FRACTIONAL SHARES

         No scrip or fractional  certificates  will be issued in connection with
the  reverse  stock  split.  Stockholders  who  ostensibly  would be entitled to
receive  fractional  shares because they hold a number of shares of Common Stock
not evenly  divisible  by ten will be entitled,  upon  surrender to the Exchange
Agent of certificates  representing such shares, to receive one additional share
of Common Stock for any fractional  share they may be entitled to.  Stockholders
may now hold "odd lots" as a result of the  reverse  stock split and as such may
be subject to increased transaction costs on the sale of their Common Stock.

         Stockholders  are  encouraged to surrender  their  certificates  to the
Exchange Agent for certificates  evidencing whole shares of the Common Stock due
them for fractional interests.  

FEDERAL INCOME TAX CONSEQUENCES

         The reverse stock split should not result in the recognition of gain or
loss (except in the case of additional  shares received for fractional shares as
described  below).  The  holding  period of the shares of new Common  Stock will
include the  stockholders'  respective  holding periods for the shares of Common
Stock exchanged therefore, provided that the shares of Common Stock were held as
a capital  asset.  The adjusted  basis of the shares of new Common Stock will be
the same as the adjusted basis of the Common Stock exchanged therefore,  reduced
by the  basis  applicable  to the  receipt  of  additional  shares  in  lieu  of
fractional shares described below.

         A  stockholder  who receives  additional  shares in lieu of  fractional
shares will be treated as if the Company would issue  additional  shares to him.
Such stockholder  should  generally  recognize gain or loss, as the case may be,
measured by the difference  between the number of additional shares received and
the basis of his old Common Stock applicable to such fractional  shares had they
actually been issued. Such gain or loss shall be a capital gain or loss (if such
stockholder's  Common Stock was held as a capital asset),  any such capital gain
or loss shall  generally  be  long-term  capital gain or loss to the extent such
stockholder's holding for his Common Stock exceeds twelve months.

NO DISSENTER'S RIGHTS

         Under Delaware law, stockholders are not entitled to dissenter's rights
of appraisal with respect to the reverse stock split.


THE BOARD OF DIRECTORS UNANIMOUSLY  RECOMMENDS A VOTE FOR PROPOSAL ONE.

    


                                       -4-


<PAGE>
   
                                  PROPOSAL TWO

                              ELECTION OF DIRECTOR

         The Company has three classes of directors serving staggered three-year
terms. Class I and Class II each consist of two directors and Class III consists
of three directors. Currently, there is one director vacancy in Class II and two
director  vacancies in Class III. One Class III director is to be elected at the
Annual  Meeting for a term of three years expiring at the Annual Meeting in 2000
or until such director's  successor  shall have been elected and qualified.  The
other directors of the Company will continue in office for their existing terms,
which expire in 1998 and 1999 for Class I and Class II directors, respectively.

         Unless authority to vote for directors is withheld, the Company intends
that the shares represented by the enclosed proxy will be voted for the election
of Robert E. Klem,  Ph.D, who is currently a member of the Board of Directors of
the Company, and a Class III Director.  In the event such nominee becomes unable
or unwilling to accept  nomination or election,  the shares  represented  by the
enclosed  proxy will be voted for the  election  of such  person as the Board of
Directors may select.  The Board of Directors has no reason to believe that such
nominee will be unable or unwilling to serve.

         The Board of Directors has not  nominated  anyone to fill the two Class
III  Director  vacancies.  Proxies  cannot  be voted for more than one Class III
Director.

         Set forth below is information  regarding the nominee for the Class III
director  and the  continuing  directors  of  Class I and  Class  II,  including
information  furnished by them as to their principal  occupations at present and
for the past five years,  certain  directorships  held by each, their ages as of
February, 1997 and the year in which each became a director of the Company.
    

         Name                                                                Age
         ----                                                                ---

         CLASS III

Robert E. Klem, Ph.D.  ....................................................   52

Dr.  Klem has been a director  of the  Company  since  February  1991 and a Vice
President of the Company since October 1991. Dr. Klem co-founded JBL Scientific,
Inc. ("JBL"), a wholly owned subsidiary of the Company, in 1973 and, since then,
has  been  Chairman  of the  Board  and  Chief  Technical  Officer  of JBL  with
responsibility for research,  development and marketing activities.  Previously,
Dr. Klem was the Plant Manager for E.I.  DuPont in Victoria,  Texas from 1970 to
1974.  Dr. Klem received his Ph.D. in Organic  Chemistry  from the University of
California at Riverside.

         CLASS I

Thomas H. Adams, Ph.D. ....................................................   53

   
Dr. Adams was the founder of the Company and has been  Chairman of the Board and
Chief Executive Officer of the Company since February 1989. He previously served
as Chairman of the Board and Chief Executive  Officer of Gen-Probe  Incorporated
("Gen-Probe"),  which he co-founded in 1984. Prior to joining Gen-Probe, he held
the  positions  of Senior Vice  President  of Research &  Development  and Chief
Technical Officer at Hybritech Incorporated ("Hybritech"),  a leading monoclonal
antibody  products  company which was acquired by Eli Lilly and Company in 1986.
He had previously  held senior  scientific  management  positions with Technicon
Instruments  Corp., the Hyland  Laboratories  Division of Baxter  Travenol,  and
DuPont.  Dr. Adams is a director of Life  Technologies,  Inc.,  a life  sciences
company,  and three  private  biotechnology  firms . He  received  his Ph.D.  in
Biochemistry from the University of California at Riverside.
    

Sharon B. Webster, Ph.D.  .................................................   59

   
Dr. Webster has been a director of the Company since February 1989. She has been
President,  Chief Executive Officer, Chairman of the Board and Managing Director
of A. A. Global, Inc., a consulting firm, since 1989. From 1988 to 1989,
    


                                       -5-


<PAGE>

she was a financial  consultant at Shearson Lehman Hutton Inc. From 1983 to 1988
Dr. Webster was an investment banker and account executive at Johnston,  Lemen &
Co.  Inc.  She  received  her Ph.D.  in  International  Political  and  Economic
Relations from the University of Virginia.


         CLASS II

Paul O.P. Ts'o, Ph.D.  ....................................................   67
   
Dr.  Ts'o has been a director  of the Company  since its  inception  in February
1988. Dr. Ts'o is currently Professor of Biophysics,  Department of Biochemistry
at The Johns Hopkins University ("Johns Hopkins"). Dr. Ts'o has been a professor
at Johns Hopkins since 1967, and was Director of the Division of Biophysics from
1973 to 1990. He received his Ph.D. from the California Institute of Technology.

         The Board of Directors held 27 meetings  during the year ended December
31,  1996.  All  directors  attended  at least  75% of the  aggregate  number of
meetings of the Board of Directors and of the committees on which such directors
had  served.  Directors  receive no fees for their  services,  but  non-employee
directors are eligible for stock options (see "Compensation of Directors").

         By letter dated October 8, 1996, James C. Blair,  Ph.D.  announced that
he would  be  resigning  as a  Director  and as Vice  Chairman  of the  Board of
Directors of the Company,  effective immediately.  Dr. Blair cited as the reason
for the  resignation  his perception that his views regarding the proper program
to  resolve  the  financial  and  strategic  issues  faced by the  Company  were
irreconcilably  different from those held by the Company's Chairman of the Board
and by a majority of the Company's Board of Directors.

         Effective  as of the close of business on October 22,  1996,  Samuel D.
Colella resigned from the Company's Board of Directors  without citing a reason.
Effective as of the close of business on January 28, 1997 David F. Hale resigned
from the Company's Board of Directors without citing a reason.

         The Board of Directors appointed an Executive Committee, a Compensation
Committee,  a Stock  Plan  Committee,  and an  Audit  Committee  in 1995 and the
designated members of such committees were designated to continue to serve until
such members'  respective  successors are duly designated and qualified or until
such members' earlier resignation or removal.

         The  Company  does  not  have  a  standing  Nominating  Committee.  The
functions  customarily  performed by a nominating committee are performed by the
Board of Directors as a whole.  Any  stockholder who wishes to make a nomination
at an  annual  or  special  meeting  for  election  of  directors  must do so in
compliance  with the applicable  procedures set forth in the Company's  By-laws.
The Company will furnish copies of such By-law provision upon written request to
the Company at the offices of the Company at 3550  General  Atomics  Court,  San
Diego, California 92121.

         The members of the Executive  Committee were Thomas H. Adams , James C.
Blair, David F. Hale and Samuel D. Colella.  The Executive  Committee held three
meetings during 1996. Subject to the ultimate direction and control of the Board
of Directors,  the Executive  Committee's function is to exercise,  with certain
exceptions,  all of the powers and  authority of the Board in the  management of
the business and affairs of the Company.

         The members of the Stock Plan  Committee  were James C. Blair and David
F. Hale.  The Stock Plan  Committee held one meeting during 1996. The Stock Plan
Committee's  functions are to supervise the administration of, and grant options
under, the 1991 Stock Plan of the Company (the "1991 Stock Plan").

         The members of the Compensation  Committee were Thomas H. Adams , James
C. Blair and David F. Hale. The  Compensation  Committee held one meeting during
1996. The  compensation  of the officers was not addressed at this meeting.  The
Compensation  Committee's  functions are to assist in the implementation of, and
provide  recommendations  with  respect to,  general and  specific  compensation
policies and practices of the Company.
    


                                       -6-


<PAGE>
   
         The members of the Audit Committee were Thomas H. Adams, James C. Blair
and Samuel D.  Colella.  The Audit  Committee  did not hold any meetings  during
1996.  The Audit  Committee's  functions  are to review  the scope of the annual
audit, monitor the independent auditor's  relationship with the Company,  advise
and assist the Board of Directors in evaluating the auditor's review,  supervise
the Company's financial and accounting organization and financial reporting, and
nominate for stockholder  approval at the annual  meeting,  with the approval of
the Board of Directors,  a firm of certified public accountants whose duty it is
to audit the financial records of the Company for the fiscal year for which they
are appointed.

         THE BOARD OF DIRECTORS UNANIMOUSLY  RECOMMENDS A VOTE FOR THE CLASS III
NOMINEE FOR DIRECTOR LISTED ABOVE.
    


                                       -7-


<PAGE>

           STOCK OWNERSHIP OF MANAGEMENT AND CERTAIN BENEFICIAL OWNERS

   
         The following  table sets forth  information  as of March 5, 1997 as to
shares of Common Stock beneficially owned by (i) the Company's  directors,  (ii)
the Company's  executive  officers named in the Summary  Compensation  Table set
forth herein,  (iii) the  directors  and executive  officers of the Company as a
group and (iv) each person  known by the Company to be the  beneficial  owner of
more than five  percent of the  outstanding  shares of the  Common  Stock of the
Company.  As of March 5 , 1997,  each  share of  Series A  Preferred  Stock  was
convertible at the option of the holder, unless previously redeemed,  into 21.40
shares of Common Stock.  Each share of Series C Preferred  Stock is  convertible
into that number of shares of Common  Stock  determined  by dividing  the sum of
$1,000 plus accrued  dividends on each share of Series C Preferred  Stock by the
conversion  price of the Series C Preferred  Stock.  The conversion price of the
Series C  Preferred  Stock is equal to 75% of the  average  of the  closing  bid
prices of the Company's  Common Stock on the Nasdaq Stock Market for a specified
period  prior to the  conversion  date.  The  number of  shares of Common  Stock
issuable upon  conversion of the Series C Preferred  Stock included in the table
set forth below is based upon the Nasdaq Stock  Market  closing bid price of the
Company's Common Stock on March 5, 1997 which was $.4375.  Except as required by
law or with respect to the creation or amendment of senior  classes of preferred
stock or creation of different series or classes of Common Stock, and in certain
other  instances,  the holders of Series A and Series C  Preferred  Stock do not
have voting rights until  conversion into Common Stock. As the conversion  rates
and  anti-dilution   adjustments  of  these  convertible  preferred  stocks  are
influenced by the market price of the Company's  Common Stock at any given time,
the  numbers  of  shares  of  Common  Stock  issuable  upon  conversion  of such
instruments  will  be  affected  by  fluctuations  in the  market  price  of the
Company's Common Stock.


                                                  Amount and Nature
                                                     of Beneficial       Percent
Name and Address of Beneficial Owner                 Ownership(1)       of Class
- ------------------------------------                 ------------       --------

Paramount Capital Asset Management, Inc..........   40,915,000(2)        51.15%
    787 Seventh Avenue
    New York, New York  10019

Institutional Venture Partners IV................    2,543,783(3)         6.12%
    3000 Sand Hill Road
    
    Building 2, Suite 290
    Menlo Park, California 94025

   
 SkyePharma Plc
    105 Piccadilly
    London W1V 9FN, England......................    2,320,561(4)         5.48%

Paul O.P. Ts'o...................................      887,000(5)         2.22%
Thomas H. Adams..................................      635,397(6)         1.58%
Robert E. Klem...................................      283,154(7)             *
Guy Van de Winckel...............................       60,000(8)             *
Sharon B. Webster................................       24,000(5)             *
Zofia E. Dziewanowska............................       85,233(8)             *
Lauren Brown.....................................      213,443(9)             *
Robert Wang......................................      85,945(10)             *
    


                                       -8-


<PAGE>

All directors and executive officers
   
    as a group (8 persons).......................  2,274,172(11)          5.62%
    
- ---------------

*        Less than one percent

   
(1)      The  number of shares  beneficially  owned is  determined  under  rules
         promulgated by the Securities and Exchange  Commission (the "SEC"), and
         the information is not necessarily  indicative of beneficial  ownership
         for any other purpose. Under such rules,  beneficial ownership includes
         any shares as to which the  individual  has sole or shared voting power
         or investment  power and also any shares which the  individual  has the
         right to  acquire  within  60 days  after  March 5,  1997  through  the
         exercise of any stock option,  convertible  security,  warrant or other
         right.  The  inclusion  herein  of  such  shares,   however,  does  not
         constitute  an  admission  that the  named  stockholder  is a direct or
         indirect beneficial owner of such shares.  Unless otherwise  indicated,
         each  person or entity  named in the  table has sole  voting  power and
         investment  power (or shares  such power with his or her  spouse)  with
         respect to all shares of capital  stock  listed as owned by such person
         or entity.

(2)      Based on  information  as of February 24, 1996 contained in a Statement
         on  Schedule  13D  filed  with  the  SEC  by  Paramount  Capital  Asset
         Management,  Inc. ("PCAM"),  Dr. Lindsay A. Rosenwald,  The Aries Fund,
         and The Aries  Domestic Fund,  L.P.  According to the Schedule 13D, Dr.
         Rosenwald and PCAM may be deemed to have shared  voting and  investment
         power  over the  26,640,500  and  14,274,500  shares of  Common  Stock,
         respectively, which may be deemed to be beneficially owned by The Aries
         Fund  and  The  Aries  Domestic  Fund,  L.P.(collectively,  the  "Aries
         Funds"). According to the Schedule 13D, The Aries Fund owns (i) 640,500
         shares of Common Stock,  (ii) $1,950,000  principal  amount of a Senior
         Secured  Bridge Note (a "Bridge Note") which,  subject to  antidilution
         adjustments,  is initially  convertible into 390,000 shares of Series D
         Preferred  Stock (the  "Series D  Preferred  Stock"),  which,  in turn,
         subject to antidilution  adjustments,  are initially  convertible  into
         13,000,000  shares of Common  Stock,  and (iii)  five-year  warrants to
         purchase  13,000,000 shares of Common Stock.  According to the Schedule
         13D, The Aries  Domestic  Fund,  L.P. owns (i) 274,500 shares of Common
         Stock, (ii) $1,050,000 principal amount of a Bridge Note which, subject
         to  antidilution  adjustments,  is initially  convertible  into 210,000
         shares  of  Series  D  Preferred  Stock,  which,  in turn,  subject  to
         antidilution  adjustments,  are initially  convertible  into  7,000,000
         shares of  Common  Stock,  and (iii)  five-year  warrants  to  purchase
         7,000,000  shares  of  Common  Stock.  Pursuant  to a Note and  Warrant
         Purchase  Agreement dated January 28, 1997 with the Company,  the Aries
         Funds have the right to appoint a majority  of the members of the Board
         of Directors of the Company;  provided,  however, that in the event the
         Company has not obtained Future  Financings (as defined in the Note and
         Warrant  Purchase  Agreement) in excess of $3,500,000 on or before July
         28,  1997,  then the Aries  Funds shall have the  contractual  right to
         appoint only two directors or observers  and, if  additional  directors
         have been appointed,  they shall be required to resign.  As of the date
         of this Proxy Statement, the Aries Funds have not exercised such right.

(3)      Consists of: (i) 875,618 shares of Common Stock and 1,628,693 shares of
         Common Stock issuable upon the  conversion of Series C Preferred  Stock
         beneficially  owned by  Institutional  Venture  Partners  IV;  and (ii)
         13,334 shares of Common Stock , 22,138 shares of Common Stock  issuable
         upon the  conversion  of Series C  Preferred  Stock  and  4,000  vested
         options to purchase Common Stock  beneficially  owned by  Institutional
         Venture Management IV.

(4)      Based on  information  as of June 26, 1996  contained in a Statement on
         Schedule 13D filed with the SEC by Jagotec AG ("Jagotec"), Jago Finance
         Limited, Jago Holding AG and SkyePharma Plc. (the "Reporting Persons").
         According  to the  Schedule  13D,  as a  result  of  SkyePharma  Plc.'s
         acquisition of Jago Holding AG, SkyePharma Plc. has become a beneficial
         owner of the Common Stock held by Jagotec and Jago Finance Limited, and
         each of the Reporting  Persons has become a member of a "group"  within
         the meaning of Section 13(d)(3) of the Securities Exchange Act of 1934,
         as amended.

(5)      Includes  4,000 shares of Common Stock which Dr. Ts'o and Dr.  Webster
         may each  acquire  within 60 days after March 5, 1997  pursuant to the
         exercise of options.
    


                                       -9-


<PAGE>
   
(6)      Includes  115,000 shares of Common Stock held in several trusts for Dr.
         Adams' children, as to which Dr. Adams has shared voting and investment
         power.  Also  includes  217,075  shares  of Common  Stock  which may be
         acquired within 60 days after March 5, 1997 pursuant to the exercise of
         options.

(7)      Includes  18,750  shares of Common Stock held by a trust for Dr. Klem's
         children,  as to which Dr. Klem has shared voting and investment power.
         Includes  1,500 shares of Common Stock owned by Dr.  Klem's wife, as to
         which he disclaims beneficial ownership. Also includes 48,076 shares of
         Common  Stock which may be acquired  within 60 days after March 5, 1997
         pursuant to the exercise of options.

(8)      These  shares  may be  acquired  within  60 days  after  March 5, 1997
         pursuant to the exercise of options.

(9)      Includes 12,865 shares of Common Stock which may be acquired within 60
         days after March 5, 1997 pursuant to the exercise of options.

(10)     Includes 42,945 shares of Common Stock which may be acquired within 60
         days after March 5, 1997 pursuant to the exercise of options.

(11)     Includes  474,194 shares of Common Stock which may be acquired  within
         60 days after  March 5, 1997  pursuant  to the  exercise  of  options.
         Includes  133,750 shares of Common Stock held by family trusts for the
         benefit of family  members of directors  and officers as to which such
         directors and officers have voting and investment power .
    


                COMPENSATION OF EXECUTIVE OFFICERS AND DIRECTORS

   
         The  following  table  sets  forth  compensation  for  services  in all
capacities  to the  Company  and its  subsidiaries,  for the fiscal  years ended
December 31, 1994 , 1995 and 1996 of: (i) those persons who were,  respectively,
at December 31, 1996 the Company's  Chief  Executive  Officer and the other four
most highly  compensated  executive  officers of the Company  whose total annual
salary and bonus for fiscal year 1996 exceeded $100,000; and (ii) one additional
individual  who would have been one of such other four most  highly  compensated
executive officers if such individual had served as an executive officer for the
entire fiscal year (collectively, the "Named Officers").
    
<TABLE>
<CAPTION>

                                                 SUMMARY COMPENSATION TABLE
                                                                                                           Long-Term
                                                          Annual Compensation                            Compensation
                                                                                                            Awards
                                                                                                          Securities
Name and                                                                          Other Annual            Underlying
Principal Position                    Year      Salary ($)       Bonus ($)       Compensation($)           Options(#)
- ------------------                    ----      ----------       ---------       ---------------           ----------
<S>                                   <C>       <C>              <C>             <C>                       <C>
   
Thomas H. Adams, Ph.D.                1996      $285,000(5)         --                 --                  27,990(5)
Chairman of the                       1995       285,000            --                                    200,000(1)
Board and Chief                       1994       283,542            --                 --                     --
    
 Executive Officer

   
Zofia E. Dziewanowska,                 1996     $235,000(5)         --                 --                  15,735(5)
Ph.D., M.D., Senior Vice               1995      235,000            --             14,759(3)              120,000(1)
President, Global Clinical             1994      137,348(2)        10,000                                 14,362 (3)
Affairs
    


                                      -10-


<PAGE>
   
Guy Van de Winckel                     1996     $170,000            --                 --                     --
Vice President, European               1995      170,000            --                 --                 60,000(1)
Operations and President               1994      170,000            --             37,000(3)                  --
of Genta Pharmaceuticals
    
Europe, S.A.

   
Robert E. Klem, Ph.D.                  1996     $155,000(5)         --              2,580(4)               8,533(5)
Vice President, Chairman               1995      161,458(8)         --             2,580 (4)              45,000(1)
of the Board of JBL                    1994      154,292            --              2,580(4)                  --

 Robert Wang                           1996     $150,000            --                 --                     --
 Vice President                        1995      135,833(6)         --                 --                 60,000(1)
 Corporate Operations                  1994      130,000            --                 --                     --

Howard Sampson(7)                      1996     $175,000            --                 --                      --
Vice President and Chief               1995      132,671            --                 --                  65,000
Financial Officer                      1994      123,958            --                 --                      --
    

- ---------------
</TABLE>

   
(1)      These  options  (the  "New  Options")  were  granted  in  exchange  for
         unexercised  options  granted  prior to April 20, 1995 with an exercise
         price above $2.25 per share (the "Old  Options").  The New Options were
         granted  at fair  market  value at the date of grant  and have the same
         vesting schedule as the Old Options.  However, the New Options were not
         exercisable until after April 20, 1997,  regardless of the Old Option's
         vesting schedule, unless the holder is terminated involuntarily without
         cause prior to April 20, 1997. None of these option have been exercised
         to date.

(2)      Dr.  Dziewanowska  joined the Company in May 1994. Dr.  Dziewanowska's
         salary for 1994 reflects a partial year of service.
    

(3)      Represents   payments  for  expenses   incurred  in  connection   with
         relocation including applicable tax gross-ups.
   
(4)      Represents payments for an insurance policy covering Dr. Klem.

(5)      Options were granted to Named Officers  during the year ended December
         31, 1996 to compensate them for accepting deferral of the payment of a
         portion of base  salary.  The  portions of  salaries  so deferred  are
         included  in the 1996  salary  figures in this  table,  consisting  of
         $35,625,  $19,583 and $12,917 for Dr. Adams, Dr.  Dziewanowska and Dr.
         Klem, respectively.

(6)      Effective  September  1, 1995 Dr.  Wang  received a salary  increase of
         $20,000  and stock  options  exercisable  for  20,000  shares of Common
         Stock.  The  additional  40,000  options  are New  Options  granted  in
         exchange for Old Options.

(7)      On  September __, 1996,   Mr.   Sampson   entered  into  an  executive
         compensation  agreement  with  the  Company  which  requires  (i)  the
         continued  payment of Mr. Sampson's salary at his then current rate of
         $175,000 until October 18, 1997, the first  anniversary of the date of
         Mr. Sampson's voluntary resignation from the Company; (ii) eligibility
         for coverage under the Company's  health insurance plan; and (iii) the
         grant of 75,000 shares of the Company Stock at no cost to Mr. Sampson.
         As of the date of this  Proxy  Statement,  such  shares  have not been
         issued to Mr. Sampson.  In 1996, Mr. Sampson  received an aggregate of
         $37,522 in severance payments under the agreement.
    


                                      -11-


<PAGE>
   
(8)      Represents 25 bi-monthly pay periods during 1995 that resulted from Dr.
         Klem's having been transferred  from the Company's  payroll calendar to
         JBL's payroll calendar in September of 1995.
    


                                      -12-


<PAGE>

COMPENSATION OF DIRECTORS

   
         Directors  of the  Company  receive  no  fees  for  their  services  as
directors or committee  members.  Non-employee  directors are  reimbursed by the
Company for their  out-of-pocket  expenses incurred in attending meetings of the
Board of Directors and its committees.  In addition,  non-employee directors are
eligible to receive  automatic grants of nonstatutory  stock options pursuant to
the 1991 Stock Plan .

          During 1996, Dr. Ts'o, a non-employee director, received $38,333 under
a consulting  agreement  between Dr. Ts'o and the Company.  The agreement may be
terminated by either party upon giving written notice to that effect.
    

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

   
         For the Company's fiscal year ended December 31, 1996, Thomas H. Adams,
James C. Blair and David F. Hale were the members of the Company's  Compensation
Committee.  Mr. Blair  resigned  from the Board of Directors on October 8, 1996.
Mr. Hale resigned from the Board of Directors on January 28, 1997.  Dr. Adams is
Chairman of the Board of Directors and Chief  Executive  Officer of the Company.
None of the executive  officers of the Company had any "interlock"  relationship
to report during the Company's fiscal year ended December 31, 1996.

         The Company's  Relationship with Jagotec. In December 1992, the Company
and Jagotec  formed Genta Jago  Technologies  BV ("Genta  Jago"),  a 50/50 joint
venture to develop and commercialize products in six major therapeutic areas.
 In 1996,  SkyePharma Plc acquired Jagotec.  Dr. Adams is a managing director of
Genta Jago.

          Among other things,  the Company is required to provide loans to Genta
Jago pursuant to a working capital  agreement which expires in October 1998. The
loans are advanced up to a mutually agreed upon maximum commitment amount, which
amount is  established  by the parties on a periodic  basis.  As of December 31,
1996,  the Company had advanced  working  capital loans of  approximately  $15.3
million to Genta Jago,  net of principal  repayments  and credits,  which amount
fully satisfied the loan commitment  established by the parties through December
31, 1996.  Such loans bear  interest and are payable in full in October 1998, or
earlier in the event  certain  revenues  are  received  by Genta Jago from third
parties.  There can be no  assurance,  however,  that Genta Jago will obtain the
necessary financial resources to repay such loans to the Company.

         Under the terms of the joint venture,  Genta Jago has  contracted  with
the  Company to conduct  research  and  development  and provide  certain  other
services.  Revenues  associated  with  providing  such  services,  totaling $1.5
million in 1996,  were  recorded by the  Company as a  reduction  of the related
research and development and general and administrative  expenses.  Terms of the
arrangement also grant the Company an option to purchase  SkyePharma's  interest
in Genta Jago exercisable from December 1998 through 2000.

          Genta Jago's  Collaboration  with Gensia.  In January 1993, Genta Jago
entered  into  a  collaboration  agreement  with  Gensia  Pharmaceuticals,  Inc.
("Gensia")  for  the   development   and   commercialization   of  certain  oral
controlled-release  pharmaceutical  products  for  treatment  of  cardiovascular
disease.  Under the  agreement,  Gensia  provided  funding for  formulation  and
preclinical  development  to be conducted by Genta Jago and is  responsible  for
clinical development,  regulatory submissions and marketing. Genta Jago received
$2.2  million,  of  research  and  development  funding in 1996  pursuant to the
agreement.

          Gensia in turn in 1994 entered into a  collaboration  with  Boehringer
Mannheim  Pharmaceuticals  Corporation  ("Boehringer") to develop and co-promote
Genta Jago's potential  nifedipine product.  Gensia transferred its rights under
this  collaboration  to Brightstone,  SkyePharma's  U.S.  subsidiary in October,
1996.

         Dr. Adams is a member of Gensia's  Scientific Advisory Board. Mr. Hale,
a former outside director, is Chairman of the Board of Directors,  President and
Chief  Executive  Officer of Gensia.  See  "Certain  Relationships  and  Related
Transactions" below.
    


                                      -13-


<PAGE>

PENSION AND LONG-TERM INCENTIVE PLANS

         The Company has no pension or long-term incentive plans.


                                      -14-


<PAGE>


                                  STOCK OPTIONS

   
         The  following  tables  summarize the option grants to and exercises by
the Named  Officers  and the value of these  options held by such persons at the
end of fiscal 1996. The Company does not grant Stock Appreciation Rights. Grants
of options to  purchase a total of 128,323  shares  were made in 1996  solely to
compensate employees for accepting deferral of a portion of their salaries.  The
Company  granted  options to purchase a total of 128,323  shares to employees in
fiscal 1996.

<TABLE>
<CAPTION>

                                             OPTION GRANTS IN FISCAL YEAR  1996
    
                                                                                              POTENTIAL REALIZABLE VALUE
                                                                                                AT ASSUMED ANNUAL RATES
                                                                                               STOCK PRICE APPRECIATION
   
                                                        INDIVIDUAL GRANTS                          FOR OPTION TERM(1)
    
                                           NUMBER OF       % OF
                                          SECURITIES   TOTAL OPTIONS   EXERCISE
                                          UNDERLYING    GRANTED TO      OR BASE
                                            OPTIONS    EMPLOYEES IN      PRICE       EXPIRATION
NAME                                      GRANTED (#)   FISCAL YEAR     ($/SH)          DATE         5%($)        10%($)
- ----                                      -----------   -----------     ------        --------     ---------    --------
<S>                                          <C>          <C>           <C>              <C>          <C>          <C>
   
Thomas H. Adams, Ph.D.................      27,990          22%      17,812 2.06         2006       23,156        58,601
                                                                     10,178 1.75         2006       11,196        28,396

Zofia E. Dziewanowska, Ph.D., M.D.....      15,735          12%       7,343 2.06         2006        9,546        24,158
                                                                      8,392 1.75         2006        9,231        23,414

Guy Van De Winckel....................          --           --            --             --           --            --

Robert E. Klem, Ph.D..................       8,533           6%       4,843 2.06         2006        6,296        15,933
                                                                      3,690 1.75         2006        4,059        10,295

 Robert Wang..........................          --           --            --             --           --            --

 Howard Sampson.......................          --           --            --             --           --            --
    
</TABLE>
- ---------------
   
(1)      Assumes that the stock prices on the relevant  grant dates ($2.0625 and
         $1.75 on February 8, 1996 and June 18, 1996,  respectively) have grown,
         as  indicated,  at:  (a) 5% per annum over the term of the  option,  to
         $3.3596 and $2.8506,  respectively;  or (b) 10% per annum over the term
         of the option,  to $5.3496 and  $4.5390,  respectively.  The 5% and 10%
         assumed  rates  of   appreciation   are  calculated   pursuant  to  the
         regulations  promulgated  by the SEC and do not represent the Company's
         estimate or projection of the future Common Stock price.
    


                                      -15-


<PAGE>

<TABLE>
<CAPTION>
                    OPTION EXERCISES IN LAST FISCAL YEAR AND
                          FISCAL YEAR END OPTION VALUES

                                                                            Number of
                                                                           Securities                 Value of
                                                                           Underlying                Unexercised
                                                                           Unexercised              In-the-Money
                                                                           Options at                Options at
                                                                       Fiscal Year End(#)       Fiscal Year End($)(1)
                                  Shares Acquired       Value
Name                              On Exercise (#)   Realized ($)     Exercisable Unexercisable  Exercisable Unexercisable
- ----                              ---------------   ------------     ----------- -------------  ----------- -------------
<S>                                     <C>              <C>             <C>          <C>            <C>         <C>
   
Thomas H. Adams, Ph.D.                   --             --             217,075       10,915          --           --

Zofia E. Dziewanowska, Ph.D., M.D.       --             --              95,908       39,827          --           --

Guy Van de Winckel                       --             --              60,000         --            --           --

Robert E. Klem, Ph.D.                    --             --              48,076        5,457          --           --

 Howard Sampson                          --             --              82,624       32,376          --           --

Robert Wang                              --             --              42,945       17,055          --           --
    
</TABLE>
- ---------------------

   
(1)      Calculated  on the basis of the fair  market  value of the  underlying
         securities  as of  December  31, 1996  ($.4375  per share),  minus the
         exercise price.


                  BOARD REPORT TO STOCKHOLDERS ON COMPENSATION

 OVERVIEW

         Although the Board of  Directors  appointed a  Compensation  Committee,
each of its independent  members resigned from the Board of Directors before the
Committee had met to make any  determinations or recommendations to the Board of
Directors as to the  compensation of the Company's  Chief Executive  Officer and
other executive  officers .  Accordingly,  this Report is being made by the full
Board of Directors.

         The Company seeks to achieve three objectives which serve as guidelines
in making compensation decisions :
    

         o        Providing a total  compensation  package which is  competitive
                  and, therefore,  enables the Company to attract and retain, on
                  a long-term basis, high-caliber executive personnel;

         o        Integrating   compensation   programs   with  the  Company's
                  short-term   and  long-term   strategic  plan  and  business
                  objectives; and

         o        Encouraging achievement of business objectives and enhancement
                  of  stockholder  value  by  providing   executive   management
                  long-term incentive through equity ownership.

   
         In making its compensation  determinations,  the Board of Directors and
prior years'  Compensation  Committees  have  relied,  in part,  on  independent
surveys  and   analyses  of   management   compensation   of  companies  in  the
biotechnology and pharmaceutical  industries  (including companies in the Nasdaq
Pharmaceutical  Stock Index used in the Company's Stock Price  Performance Graph
set forth in this Proxy Statement) and recommendations of management.  The Board
of Directors believes it has established executive compensation levels which are
competitive with companies in the  biotechnology and  pharmaceutical  industries
when taking into account relative company size, stage of development, individual
responsibilities  and experience,  individual and overall corporate  performance
and geographic location.
    


                                      -16-


<PAGE>

COMPONENTS OF EXECUTIVE COMPENSATION

         The Company's potential  therapeutic  products are in various stages of
research  and  development,  and no  revenues  have as yet been  generated  from
therapeutic  product  sales.  As a result,  the use of  traditional  performance
standards,  such as corporate profitability,  are not believed to be appropriate
in  the  evaluation  of  the  performance  of  the  Company  or  its  individual
executives.  The compensation of the Company's  executive  officers is based, in
substantial  part,  on the  achievement  of  individual  and  overall  corporate
objectives. Such objectives are established and modified as necessary to reflect
changes  in  market  conditions,  and  other  factors.  Individual  and  overall
corporate   performance  is  measured  by  reviewing   whether  these  corporate
objectives have been achieved.

         The Company's  compensation  package for executive  officers  generally
consists of annual cash  compensation and long-term  compensation in the form of
stock  options.  In light of the Company's  stage of  development,  considerable
emphasis is placed on equity-based compensation in an effort to preserve cash to
finance the Company's research and development efforts.

ANNUAL CASH COMPENSATION

   
         Compensation   levels  for  the   Company's   executive   officers  are
determined, in part, through comparisons with companies of a similar size, stage
of development and level of complexity in the biotechnology  and  pharmaceutical
industries,  and other companies with which the Company  competes for personnel.
In addition,  the  compensation  level for each  executive  officer  reflects an
evaluation  of the  responsibilities  required  for  each  respective  position,
individual  experience  levels,  and individual  performance  and  contributions
toward achievement of the Company's business objectives. The compensation levels
for the Company's executive officers, including the Chief Executive Officer, are
designed  to be  competitive  within  a range  that the  Compensation  Committee
determines to be reasonable in light of the aforementioned factors. Compensation
levels are generally set at the midrange of the comparable companies in order to
remain  competitive  and  attract  key  personnel.  The  salary  levels  of each
executive  officer are reviewed on an annual basis and  adjustments  are made as
deemed necessary.
    

STOCK OPTIONS

   
         The Board of Directors of the Company  believes  that by providing  all
full-time  employees,  including  executive officers who have responsibility for
the  management  and growth of the  Company,  with an  opportunity  to obtain an
equity  interest  in  the  Company,  the  best  interests  of  stockholders  and
executives  will be  closely  aligned.  Accordingly,  all  full-time  employees,
including executive  officers,  are eligible to receive stock option grants from
time to time,  giving them the right to purchase shares of the Company's  Common
Stock at a specified price.

COMPENSATION OF EXECUTIVE OFFICERS

         In making compensation  decisions for 1996, the Board of Directors took
into account the Company's limited cash resources,  weakened financial condition
and general  financial  performance  during 1996 and the importance of retaining
the Company's cash to finance its development programs,  but also considered the
importance to the Company of retaining highly qualified key personnel due to the
complex and technologically  sophisticated nature of the Company's business.  In
light of these  factors,  it was decided to increase  the base  salaries of Drs.
Klem and Brown to  competitive  levels in the  industry  and not to increase the
base salary of any other executive  (other than Mr. Sampson) beyond 1995 levels,
not to award any bonuses and to request that certain  executives defer a portion
of their base salary. The Board granted stock options in 1996 only to compensate
the executives for such deferral of base salary.  The above  disclosure does not
apply to Mr.  Sampson,  the former Chief Financial  Officer of the Company,  who
informed  the Company in  September,  1996 that he would not continue to perform
essential  duties for the  Company  unless  the  Company  entered an  employment
contract,  effective  as of January 1, 1996,  on terms  acceptable  to him.  See
footnote  7 to the  Summary  Compensation  Table  set forth  under  the  caption
"Compensation  of  Executive  Officers and  Directors."  In light of the serious
economic  issues  faced by the Company at that time the  Company  felt it had no
alternative but to enter into such employment contract.
    


                                      -17-


<PAGE>
   
         This Compensation  Report shall not be deemed incorporated by reference
by any general  statement  incorporating  by reference this Proxy Statement into
any filing under the Securities Act of 1933 or under the Securities Exchange Act
of 1934, except to the extent the Company specifically  incorporates this report
by reference, and shall not otherwise be deemed filed under such Acts.

                                                   Thomas H. Adams, Ph.D.

                                                   Robert E. Klem, Ph. D.

                                                   Paul O.P. Ts'o, Ph.D.

                                                   Sharon B. Webster, Ph.D.
    


                                      -18-


<PAGE>

                          STOCK PRICE PERFORMANCE GRAPH

   
         The  following   graph   illustrates  a  comparison  of  the  five-year
cumulative  total  stockholder  return  (change in stock  price plus  reinvested
dividends)  of the  Company's  Common Stock with the CRSP Total Return Index for
The Nasdaq National Market (U.S. and Foreign) (the "Nasdaq Composite Index") and
the CRSP  Total  Return  Index for Nasdaq  Pharmaceutical  Stocks  (the  "Nasdaq
Pharmaceutical  Index")/1/. The comparisons in the graph are required by the SEC
and are not intended to forecast or be indicative of possible future performance
of the Company's Common Stock.
    



[GRAPHIC OMITTED]



   
<TABLE>
<CAPTION>
                                     December 31,   December 31,    December 31,   December  30,   December 29,    December 31,
                                         1991           1992            1993            1994           1995            1996
                                     -----------    ------------    -----------    -------------   ------------    ------------
<S>                                       <C>          <C>             <C>              <C>             <C>             <C>

Genta Incorporated..................     $100          $92.31          $75.69          $52.56          $25.64          $4.99
 Nasdaq Composite...................      100          116.03          134.32          130.28          182.96         224.06
Nasdaq Pharmaceutical...............      100           83.22           74.17           55.83          102.05         102.44
</TABLE>
         Assumes a $100 investment on December 31, 1991 in each of the Company's
Common Stock,  the securities  comprising the Nasdaq  Composite  Index,  and the
securities comprising the Nasdaq Pharmaceutical Index.
    
- -------- 
/1/ The Nasdaq  Pharmaceutical Index includes all companies on Nasdaq within SIC
code  283.  A  copy  of  the  list  of  companies   which  comprise  the  Nasdaq
Pharmaceutical   Index  may  be  obtained  upon  request  by  contacting   Genta
Incorporated,  Investor  Relations,  3550  General  Atomics  Court,  San  Diego,
California 92121 (619) 455-2700.


                                      -19-


<PAGE>
   
                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         In February  1989.  the Company  entered into a license  agreement with
Drs. Paul Ts'o and Paul Miller (the "Ts'o/Miller  Agreement")  pursuant to which
Drs.  Ts'o and Miller  granted an  exclusive  license to the  Company to certain
issued patents,  patent applications and related technology regarding the use of
nucleic   aids   and   oligonucleotides,    including   methylphosphonates,   as
pharmaceutical  agents. Dr. Ts'o is a Director of the Company and a Professor of
Biophysics,  Department of  Biochemistry  at Johns Hopkins,  and Dr. Miller is a
Professor of  Biochemistry,  at the School of Public  Health and Hygiene,  Johns
Hopkins.  In May 1990, the Company  entered into a license  agreement with Johns
Hopkins  (the  "Johns  Hopkins  Agreement"  and the  Ts'o/Miller  Agreement  are
together referred to as the "Ts'o/Miller/Hopkins  Agreements") pursuant to which
Johns Hopkins granted the Company an exclusive  license to its rights in certain
issued patents, patent applications and related technology developed as a result
of research  conducted at Johns  Hopkins by Drs.  Ts'o and Miller and related to
the use of nucleic acids and  obligonucleotides  as  pharmaceutical  agents.  In
addition,  Johns  Hopkins  has  granted  the  Company  certain  rights  of first
negotiation to inventions made by Drs. Ts'o and Miller in their  laboratories in
the area of  oligonucleotides  and  inventions  made by  investigators  at Johns
Hopkins in the course of research  funded by the Company,  which  inventions are
not otherwise included in the  Ts'o/Miller/Hopkins  Agreements.  The Company has
agreed to pay Dr. Ts'o,  Dr. Miller and Johns Hopkins  royalties on net sales of
products  covered by the issued  patents  and patent  applications,  but not the
related  technology,  licensed  to the  Company  under  the  Ts'o/Miller/Hopkins
Agreement. The Company has also agreed to pay certain minimum royalties prior to
commencement  of  commercial  sales of such  products,  which  royalties  may be
credited under certain conditions against royalties payable on subsequent sales.
Subject  to  certain  rights  of  early  termination,   the  Ts'o/Miller/Hopkins
Agreements remain in effect for the life of the  last-to-expire  patent licensed
under the respective  agreements or until abandonment of the last-pending patent
application licensed under the respective agreements.

         As of  December  31, 1996 the Company  owed Johns  Hopkins  $627,271 of
which  $200,000 is for the royalty  payments due for 1995 and 1996. In February,
1997 the Company paid Johns Hopkins $100,000 towards the 1995 royalties due. The
Company is in the process of  negotiations  with Johns Hopkins as to the payment
of a portion of the balance in securities rather than cash.

         In July 1991, a trust as to which Mr. Hale, a former Board member,  has
shared  voting  and  investment  power  acquired  25,000  shares of  convertible
preferred  stock of the  Company  (which  converted  into  12,500  shares of the
Company's Common Stock upon the closing of the Company's initial public offering
in December 1991) at a purchase price of $50,000, including a promissory note of
$49,975,  secured by the shares of stock.  The note, which bears interest at the
rate of 8% per annum (compounded annually), had an outstanding balance including
accrued interest of approximately $76,380 at December 31, 1996, and, as amended,
was  forgiven by the Board of  Directors  on December 30, 1996 in return for the
cancellation  of the 12,500 shares of Common Stock which secured the note. As of
March 5, 1997 this cancellation has not yet been effected.

         In February  1991,  in  connection  with the  acquisition  of JBL,  the
Company  assumed  certain leases  between JBL and Granada  Associates and Sueldo
Associates,  both of which are  affiliates of Drs.  Brown and Klem. Dr. Brown is
currently  Vice  President of the Company and President of JBL. Dr. Klem is Vice
President of the Company and Chairman of the Board of JBL. The current aggregate
monthly payment under such leases is approximately $32,000.

         In January 1993, Genta Jago entered into a collaboration agreement with
Gensia   for   the   development   and   commercialization   of   certain   oral
controlled-release  pharmaceutical  products  for  treatment  of  cardiovascular
disease  (the  "Gensia  Agreement").  Under  the  Gensia  Agreement,  Gensia  is
responsible for clinical development,  regulatory submissions and marketing, and
funds Genta Jago's formulation and preclinical development.  Genta Jago received
$2.2  million,  $1.9  million,  $4.9  million and $2.0  million of research  and
development funding in 1996, 1995, 1994 and 1993, respectively,  pursuant to the
Gensia Agreement.  Terms of the Gensia Agreement provide Gensia exclusive rights
to market and distribute the products in North America, Europe and certain other
territories. In connection with the Gensia Agreement and a collaboration between
Boehringer  and  Gensia  to  develop  and  co-promote   Genta  Jago's  potential
nifedipine  product,  Genta Jago  received  $1.1 million in revenues in November
1994 and may receive  additional  milestone  payments  triggered upon regulatory
submissions  and approvals,  as well as royalties or profit sharing ranging from
10 to 21 percent of product sales, if any.  Genta's Chairman and Chief Executive
Officer is a member of  Gensia's  Scientific  Advisory  Board.  In October  1996
SkyePharma  Plc signed a letter of intent  with  Gensia and  Boehringer  whereby
Brightstone, SkyePharma's U.S. subsidiary
    


                                      -20-


<PAGE>
   
would assume  Gensia's rights to develop an AB rated  bio-equivalent  version of
Pfizer's procardia XL in collaboration with Boehringer.
    


                                      -21-


<PAGE>
   
                                 PROPOSAL THREE
               RATIFICATION OF APPOINTMENT OF INDEPENDENT AUDITORS

         The Board of  Directors  has  selected the firm of Ernst & Young LLP as
the Company's  independent auditors for the fiscal year ended December 31, 1997,
subject to ratification by the stockholders at the Annual Meeting. Ernst & Young
LLP has audited the Company's financial statements since the Company's inception
in  February  1988.  Representatives  of Ernst & Young  LLP are  expected  to be
present  at the  Annual  Meeting.  They  will  have  an  opportunity  to  make a
statement,  if they desire to do so, and are expected to be available to respond
to appropriate questions.

         THE  BOARD OF  DIRECTORS  UNANIMOUSLY  RECOMMENDS  A VOTE FOR  PROPOSAL
THREE.
    


                                      -22-


<PAGE>

                              STOCKHOLDER PROPOSALS

   
         Proposals of  stockholders  intended to be presented at the 1998 annual
meeting of  stockholders  of the Company  must be received by the Company at the
offices of the Company,  at 3550 General  Atomics Court,  San Diego,  California
92121 no later  than  November  14,  1997 in order to be  included  in the proxy
statement and form of proxy relating to such annual meeting.

             SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

         Under Section 16(a) of the Securities Exchange Act of 1934, as amended,
the Company's  directors,  executive  officers and any persons holding more than
10% of the Company's Common Stock are required to report their initial ownership
of the Company's  Common Stock and any  subsequent  changes in that ownership to
the SEC.  Specific  due dates for these  reports have been  established  and the
Company is required to identify in this proxy statement those persons who failed
to timely file these  reports.  All of the filing  requirements  were  satisfied
except  for an Annual  Statement  on Form 5 for  Robert  Wang.  In  making  this
disclosure,  the Company  has relied  solely on written  representations  of its
directors and executive  officers and copies of the reports that have been filed
with the SEC.
    

                                  OTHER MATTERS

   
         The  Board  of  Directors  knows  of no  other  business  that  will be
presented  at the Annual  Meeting.  If any other  business is  properly  brought
before the Annual Meeting, it is intended that proxies in the enclosed form will
be voted in accordance with the judgment of the persons voting the proxies.



         Whether you intend to be present at the Annual  Meeting or not, we urge
you to return your signed proxy promptly.
    

                                      By order of the Board of Directors,


                                      Thomas H. Adams
                                      Chairman of the Board and
                                      Chief Executive Officer

   
Dated:   March 14, 1997
    


                                      -23-


<PAGE>

                                                                      EXHIBIT A

                            CERTIFICATE OF AMENDMENT
                                       OF
                      RESTATED CERTIFICATE OF INCORPORATION
                                       OF
                               GENTA INCORPORATED

         GENTA INCORPORATED,  a corporation  organized and existing under and by
virtue of the General Corporation Law of the State of Delaware,

         DOES HEREBY CERTIFY:

         FIRST:   That  at  a  meeting  of  the  Board  of  Directors  of  Genta
Incorporated,  resolutions were duly adopted setting forth a proposed  amendment
of the Restated  Certificate of Incorporation of the corporation,  and declaring
that such amendment is advisable and that such amendment  should be submitted to
the stockholders of the corporation for approval.  The resolution  setting forth
the proposed amendment is as follows:

                  RESOLVED,  that the first paragraph of Section A of Article IV
of the Restated Certificate of Incorporation, as amended, of this corporation be
amended to substantially read as follows:

   
                  "A.  Classes  of  Stock.  The  total  number  of shares of all
         classes of capital stock which the corporation  shall have authority to
         issue is  seventy-five  million  (75,000,000)  of which seventy million
         (70,000,000)  shares of the par value of One Tenth of One Cent  ($.001)
         each  shall be Common  Stock  (the  "Common  Stock")  and Five  Million
         (5,000,000)  shares of the par  value of One Tenth of One Cent  ($.001)
         each shall be Preferred Stock (the "Preferred Stock"). At the time this
         amendment becomes  effective,  each ten shares of the Common Stock, par
         value  of  One  Tenth  of  One  Cent  ($.001)  per  share,  issued  and
         outstanding  at such  time  shall  be,  and  hereby  are,  reduced  and
         converted into one fully paid and nonassessable  share of Common Stock,
         par  value  of  One  Tenth  of  One  Cent  ($.001)  per  share,  of the
         corporation as herein authorized. Each outstanding stock certificate of
         this  corporation  which  immediately  prior to the time this amendment
         becomes  effective  represented one or more shares of Common Stock, par
         value of One Tenth of One Cent  ($.001)  per  share,  shall  thereafter
         represent the number of whole shares of Common Stock,  par value of One
         Tenth of One Cent ($.001) per share,  determined by dividing the number
         of shares represented by such certificate immediately prior to the time
         this amendment  becomes effective by ten and rounding such number up to
         the nearest whole integer. The amount of capital represented by the new
         shares in the  aggregate  at the time  this  Certificate  of  Amendment
         becomes effective shall be adjusted by the transfer of One Tenth of One
         Cent  ($.001)  from the  capital  account  of the  Common  Stock to the
         additional  paid in capital  account for each new share issued  (except
         for new shares issued as the result of rounding up fractional shares in
         which case no capital  adjustment  shall be made),  such transfer to be
         made at such time.  The  corporation  shall not be required to issue or
         deliver  any  fractional  shares  of  Common  Stock.   There  shall  be
         designated  as capital in respect of such new shares an amount equal to
         the aggregate par value of such shares.  Upon  surrender by a holder of
         Common Stock of a certificate  or  certificates  for Common Stock,  par
         value of One Tenth of One Cent ($.001), duly endorsed, at the office of
         the  corporation,   the  corporation  shall,  as  soon  as  practicable
         thereafter,  issue and  deliver at such office to such holder of Common
         Stock,  or to the nominee or nominees of such holder,  a certificate or
         certificates for the number of shares of Common Stock, par value of One
         Tenth of One Cent  ($.001)  per share,  to which such  holder  shall be
         entitled as aforesaid."
    

         SECOND: Thereafter,  pursuant to resolutions of the corporation's Board
of Directors, the amendment was submitted to the stockholders of the corporation
for approval at a Meeting of Stockholders,  and such meeting was called and held
upon notice in accordance with Section 222 of the General Corporation Law of the
State of Delaware.  The  necessary  number of shares as required by statute were
voted in favor of the amendment.


                                       -1-


<PAGE>

         THIRD:  The said  amendment  was duly  adopted in  accordance  with the
provisions  of  Section  242 of the  General  Corporation  Law of the  State  of
Delaware.
   
                  IN  WITNESS   WHEREOF,   said   corporation  has  caused  this
certificate to be signed by Thomas H. Adams,  its Chairman of the Board,  and by
Robert Wang, its Vice President, as of this ____ day of ________, 1997.
    

                                                  GENTA INCORPORATED



                                                  By ___________________________
                                                         Thomas H. Adams
                                                       Chairman of the Board

Attest:



- ------------------------------
           Robert Wang
          Vice President


                                       -2-


<PAGE>

                               GENTA INCORPORATED
               PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
   
                      FOR ANNUAL MEETING ON APRIL 4, 1997.

         The  undersigned  stockholder  of Genta  Incorporated  (the  "Company")
acknowledges  receipt  of Notice  of  Annual  Meeting  of  Stockholders  and the
Stockholders'  Proxy  Statement  each dated March 14,  1997 and the  undersigned
revokes all prior proxies and appoints  Thomas H. Adams , Robert Wang, or either
of them,  proxies for the  undersigned to vote all shares of Common Stock of the
Company  which the  undersigned  would be  entitled  to vote at the  Meeting  of
Stockholders  to be held at the Hyatt Regency,  3777 La Jolla Village Drive,  La
Jolla,  California  at  11:00  a.m.  on April 4,  1997 and any  postponement  or
adjournment thereof, and instructs said proxies to vote as follows:

         1.    APPROVAL  FOR A ONE  FOR  TEN  REVERSE  SPLIT  OF  THE  COMPANY'S
               OUTSTANDING COMMON STOCK AND DECREASE IN THE NUMBER OF AUTHORIZED
               SHARES OF COMMON STOCK:
    

         [ ]      FOR              [ ]      AGAINST             [ ]      ABSTAIN


   
         2.    ELECTION OF DIRECTORS:

         [ ]  FOR the Class III nominee listed below


         [ ]  WITHHOLD AUTHORITY  to vote for the Class III nominee listed below

         Robert E. Klem, Ph.D.


         3.    TO RATIFY THE APPOINTMENT OF ERNST & YOUNG LLP AS THE INDEPENDENT
               AUDITORS OF THE COMPANY:


         [ ]      FOR              [ ]      AGAINST             [ ]      ABSTAIN


         4 .   In their discretion, the proxies are authorized to vote upon such
               other business as may properly come before the meeting.
    


<PAGE>

   
THIS PROXY  WILL BE VOTED IN  ACCORDANCE  WITH THE  SPECIFICATIONS  MADE.  IF NO
SPECIFICATIONS  ARE MADE,  THIS PROXY WILL BE VOTED FOR  APPROVAL OF THE REVERSE
STOCK SPLIT AND REDUCTION IN THE NUMBER OF AUTHORIZED  SHARES OF COMPANY  COMMON
STOCK,  FOR THE  ELECTION  OF THE CLASS III NOMINEE  FOR  DIRECTOR,  AND FOR THE
RATIFICATION OF THE APPOINTMENT OF ERNST & YOUNG LLP AS INDEPENDENT AUDITORS.
    

                                   GENTA INCORPORATED
                                   BOARD OF DIRECTORS PROXY
   
                                   Meeting of Stockholders  April 4, 1997



                                   Dated :
    



                                   -------------------------------------------- 
                                            (Signature of Stockholder)



                                   ---------------------------------------------
                                            (Signature of Stockholder)

         Please sign exactly as your name or names appear  hereon.  When signing
as attorney,  executor,  administrator,  trustee or  guardian,  please give full
title as such. If shares are held jointly, each holder must sign.

           PLEASE MARK, SIGN, DATE AND MAIL THIS PROXY CARD PROMPTLY,
                          USING THE ENCLOSED ENVELOPE.



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