GENTA INCORPORATED /DE/
8-K, 1998-11-03
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                    FORM 8-K

                                 CURRENT REPORT


     PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934



Date of Report (Date of earliest event reported):  October 28, 1998


                               GENTA INCORPORATED
             (Exact name of registrant as specified in its charter)

                         Commission file number 0-19635

           Delaware                                      33-0326866
(State or other jurisdiction of             (IRS Employer Identification Number)
incorporation or organization)


                 3550 General Atomics Court, San Diego, CA 92121
                    (Address of principal executive offices)
                                   (Zip Code)


                                 (619) 455-2700
              (Registrant's telephone number, including area code)


<PAGE>



                               GENTA INCORPORATED

                                    FORM 8-K

                                 CURRENT REPORT

                                TABLE OF CONTENTS


Item 4.  Changes in Registrant's Certifying Accountant

Item 7.  Financial Statements, Pro Forma Financial Information and Exhibits

Signature


                                      - 2 -

<PAGE>

ITEM 4. CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT

         On  October  28,  1998,  Ernst  & Young  LLP  ("E&Y")  resigned  as the
principal independent accountant of Genta Incorporated (the "Registrant").

         E&Y's auditor's  reports on the financial  statements of the Registrant
for the years ended  December 31, 1997 and  December  31, 1996 each  contained a
separate  explanatory   paragraph  stating  that  the  Registrant  has  suffered
recurring losses which raise substantial doubt as to the Registrant's ability to
continue as a going concern.

         During the Registrant's two most recent fiscal years and the subsequent
interim period  preceding the  resignation  of E&Y, there were no  disagreements
with  E&Y on  any  matter  of  accounting  principles  or  practices,  financial
statement disclosure or auditing scope or procedures,  which  disagreements,  if
not resolved to the  satisfaction of E&Y, would have caused it to make reference
to the subject matter of the  disagreements in connection with its report.  None
of the reportable events listed in Item 304 (a)(1)(v) of Regulation S-K occurred
with respect to the Registrant  during the  Registrant's  two most recent fiscal
years and the subsequent interim period preceding the resignation of E&Y.

         The Registrant has begun the process of seeking to retain an accounting
firm to audit the Registrant's consolidated financial statements for the current
fiscal year ending December 31, 1998.

ITEM 7. FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS

(c) Exhibits

16. Letter of Ernst & Young LLP, dated October 28, 1998, to Genta Incorporated.

23. Letter of Ernst & Young LLP,  dated  November 2, 1998, to the Securities and
Exchange Commission.


                                      - 3 -

<PAGE>

                                    SIGNATURE

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.



                                                   GENTA INCORPORATED



Date: November 3, 1998                            /s/ Kenneth G. Kasses, Ph.D.
                                                  ----------------------------
                                                  Kenneth G. Kasses, Ph.D.
                                                  President, Chief 
                                                  Executive Officer and 
                                                  Chairman of the Board


                                      - 4 -



October 28, 1998


Mr. Kenneth G. Kasses
Chief Executive Officer
Genta Incorporated
3550 General Atomics Court
San Diego, California  92121


Dear Mr. Kasses:

This  is  to  confirm  that  the  client-auditor   relationship   between  Genta
Incorporated (Commission File Number 0-19635) and Ernst & Young LLP has ceased.

                                                      Very truly yours,

                                                      /s/ Ernst & Young LLP






cc:  Office of the Chief Accountant
     SECPS Letter File
     Securities and Exchange Commission
     Mail Stop 11-3
     450 Fifth Street, N.W.
     Washington, D.C.  20549



                       [Letterhead of Ernst & Young LLP]


November 2, 1998

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC 20549

Gentlemen:

We have read Item 4 of Form 8-K dated  October 28, 1998,  of Genta  Incorporated
and are in agreement with the statements contained in the first three paragraphs
therein.  We have no basis to agree or  disagree  with other  statements  of the
registrant contained therein.


                                                           /s/ Ernst & Young LLP




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