GENTA INCORPORATED /DE/
SC 13D/A, 1998-11-09
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 8)*

                               Genta Incorporated
                               ------------------
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
                         (Title of Class of Securities)

                                  372 45 M 20 7
                                  -------------
                                 (CUSIP Number)

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:
David R. Walner, Esq.                                  Monica C. Lord, Esq.
Paramount Capital Asset                                Kramer Levin
   Management, Inc.                                      Naftalis & Frankel LLP
787 Seventh Avenue                                     919 Third Avenue
New York, NY 10019                                     New York, NY  10022
(212) 554-4372                                         (212) 715-9100

(Name,  Address and Telephone Number of Person Authorized to Receive Notices and
Communications)

                                 November 1, 1998
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:
   [_]

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                               Page 1 of 20 Pages


<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 2 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Paramount Capital Asset Management, Inc.
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|

- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER    
           REPORTING                                                           
             PERSON                                     16,716,858
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER 
                                                                               
                                                        None                   
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        16,716,858
- --------------------------------------------------------------------------------

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           16,716,858
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           69.5% (44.5% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON*
           CO
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of November 1, 1998,  Paramount  Capital
Asset Management,  Inc. may be deemed beneficially to own (within the meaning of
Rule 13d-3 under the  Securities  Exchange Act of 1934, as amended) 44.5% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.


<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 3 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Aries Domestic Fund, L.P.
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|

- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER     
           REPORTING                                                            
             PERSON                                     5,660,284              
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        None
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        5,660,284
- --------------------------------------------------------------------------------
11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           5,660,284
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           40.2% (17.3% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON*
           PN
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders  of the Issuer.  As of November 1, 1998, the Aries Domestic
Fund,  L.P. may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934, as amended)  17.3% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>


- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 4 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           The Aries Trust
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|
- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Cayman Islands

- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER     
           REPORTING                                                            
             PERSON                                     11,056,575              
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        None                    
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER

                                                        11,056,575
- --------------------------------------------------------------------------------

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           11,056,575
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           59.0% (31.6% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON* OO (see Item 2)
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of November 1, 1998, The Aries Trust may
be deemed  beneficially  to own  (within  the  meaning of Rule  13d-3  under the
Securities Exchange Act of 1934, as amended) 31.6% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>



- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 5 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Lindsay A. Rosenwald, M.D.
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      |_|
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 OO (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                    7         SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            2,866,393
                  OWNED BY                  ------------------------------------
                    EACH                      8         SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               16,716,858              
                    WITH                    ------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        2,866,393
                                            ------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        16,716,858              
- --------------------------------------------------------------------------------
      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 19,583,252
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 72.8% (48.5% of the outstanding voting power)**
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON*
                 IN

- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote  of  stockholders  of the  Issuer.  As of  November  1,  1998,  Lindsay  A.
Rosenwald,  M.D. may be deemed  beneficially  to own (within the meaning of Rule
13d-3  under the  Securities  Exchange  Act of 1934,  as  amended)  48.5% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.

<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 6 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Hawkins Group, LLC
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      [x]
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 00 (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                      7       SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            None
                  OWNED BY              ----------------------------------------
                    EACH                        8       SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               526,737 
                    WITH                ----------------------------------------
                                                9       SOLE DISPOSITIVE POWER
                                                                              
                                                        None             
                                        ----------------------------------------
                                               10       SHARED DISPOSITIVE POWER
                                                                              
                                                        526,737
- --------------------------------------------------------------------------------

      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 526,737
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 5.7% (1.7% of the outstanding voting power)**
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON
                 00 (see Item 2)
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer. As of November 1, 1998, Mr. Michael S. Weiss
may be deemed  beneficially  to own  (within the meaning of Rule 13d-3 under the
Securities  Exchange Act of 1934, as amended) 1.7% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>


- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 7 of 20 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Mr. Michael S. Weiss
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      [x]
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 PF (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                      7       SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            148,327
                  OWNED BY              ----------------------------------------
                    EACH                        8       SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               526,737                 
                    WITH                ----------------------------------------
                                                9       SOLE DISPOSITIVE POWER
                                                                              
                                                        148,327              
                                        ----------------------------------------
                                               10       SHARED DISPOSITIVE POWER
                                                                              
                                                        526,737
- --------------------------------------------------------------------------------

      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 675,064
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 7.1% (2.2% of the outstanding voting power)**
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON*
                 IN
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer. As of November 1, 1998, Mr. Michael S. Weiss
may be deemed  beneficially  to own  (within the meaning of Rule 13d-3 under the
Securities  Exchange Act of 1934, as amended) 2.2% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>



                                  SCHEDULE 13D


         This  Amendment  No. 8  amends  and  restates  the  Reporting  Persons'
Statement on Schedule 13D,  dated  February 24, 1997,  as amended to date,  (the
"Schedule") in its entirety.

Item 1. Security and Issuer.

         (a) This  Statement  on Schedule 13D (the  "Statement")  relates to the
Common  Stock,  $.001 par value (the "Common  Stock") of Genta  Incorporated,  a
Delaware  corporation  (the "Issuer").  The principal  executive  offices of the
issuer are located at 3550 General Atomics Court, San Diego, California 92121.

Item 2. Identity and Background.


     (a)  This  statement  is  filed  on  behalf  of  Paramount   Capital  Asset
          Management,  Inc.  ("Paramount  Capital"),  Aries Domestic Fund,  L.P.
          ("Aries  Domestic"),  The Aries Trust ("Aries Trust"),  Dr. Lindsay A.
          Rosenwald  (together with Paramount Capital,  Aries Domestic and Aries
          Trust,  the "Aries  Reporting  Persons")  Mr.  Michael S.  Weiss,  and
          Hawkins Group,  LLC ("Hawkins" and,  together with the Aries Reporting
          Persons and Mr. Weiss, the "Filing Persons").  See attached Exhibit AC
          which is a copy of their  agreement in writing to file this  statement
          jointly on behalf of each of them.  Mr.  Weiss,  Hawkins and the Aries
          Reporting  Persons  have made,  and will  continue to make,  their own
          investment decisions. The investment decisions of Mr. Weiss or Hawkins
          may or may not coincide with the decisions made by the Aries Reporting
          Persons.  Each  Filing  Person  expressly  disclaims  Mr.  Weiss'  and
          Hawkins'  membership  in a "group"  with the Aries  Reporting  Persons
          within the meaning of Rule 13d-5(b)(1) of the Securities  Exchange Act
          of 1934, as amended.

     (b)  The  business  address  of  Paramount  Capital,  Aries  Domestic,  Dr.
          Rosenwald,  Mr. Weiss and Hawkins is 787 Seventh  Avenue,  48th Floor,
          New York, New York, 10019. The business address for Aries Trust is c/o
          MeesPierson (Cayman) Limited,  P.O. Box 2003, British American Centre,
          Phase 3, Dr. Roy's Drive, George Town, Grand Cayman.

     (c)  Dr.  Rosenwald  is an  investment  banker,  venture  capitalist,  fund
          manager and sole  shareholder of Paramount  Capital,/1/ a Subchapter S
          corporation  incorporated in the State of Delaware.  Paramount Capital
          is the General Partner of Aries Domestic,/2/

  --------  
     /1/  Please see Exhibit B, filed herewith, indicating  the executive 
          officers and directors of Paramount Capital and providing information 
          called for by Items 2-6 of this  statement  as to said  officers and
          directors.  Exhibit B is herein  incorporated  by reference.  

     /2/  Please see Exhibit C indicating the general  partner of Aries Domestic
          and  the  general  partner's  executive  officers  and  directors  and
          providing  information called for by Items 2-6 of this statement as to
          said general  partners,  officers and  directors.  Exhibit C is herein
          incorporated by reference.


                               Page 8 of 20 Pages

<PAGE>

          a limited partnership organized under the laws of Delaware.  Paramount
          Capital is the Investment  Manager to Aries Trust,/3/ a Cayman Islands
          Trust. Mr. Weiss is the Managing Member of Hawkins,  a Senior Managing
          Director of Paramount Capital, Inc. ("PCI") and also is a Director and
          Vice Chairman of the Issuer's Board of Directors. Hawkins is a limited
          liability company organized under the laws of Delaware./4/

     (d)  Dr. Rosenwald,  Mr. Weiss, Hawkins,  Paramount Capital, Aries Domestic
          and Aries  Trust  and their  respective  managing  members,  officers,
          directors,  general partners,  investment managers,  and trustees have
          not, during the five years prior to the date hereof, been convicted in
          a  criminal  proceeding   (excluding  traffic  violations  or  similar
          misdemeanors).

     (e)  Dr. Rosenwald,  Mr. Weiss, Hawkins,  Paramount Capital, Aries Domestic
          and Aries  Trust  and their  respective  managing  members,  officers,
          directors,  general partners,  investment managers,  and trustees have
          not been, during the five years prior to the date hereof, parties to a
          civil  proceeding  of a judicial or  administrative  body of competent
          jurisdiction,  as a result of which such person was or is subject to a
          judgment,  decree or final order  enjoining  future  violations of, or
          prohibiting  or  mandating  activities  subject  to,  Federal or State
          securities laws or finding any violation with respect to such laws.

     (f)  Dr. Rosenwald and Mr. Weiss are citizens of the United States.


Item 3. Source and Amount of Funds or Other Consideration

         On February 13, 1997,  pursuant to Senior  Secured  Convertible  Bridge
Notes (the "Notes"), Aries Domestic used its general funds to lend $1,050,000 to
the Issuer and the Aries Trust used its general funds to lend  $1,950,000 to the
Issuer  (collectively,  the "Loans").  The Notes were  convertible  upon certain
events  into a number of shares of Series D  Convertible  Preferred  Stock at an
initial  conversion  price equal to five  dollars  ($5.00) per share  subject to
adjustment  upon the  occurrence  of certain  events.  Section 3 of the Note and
Warrant Purchase

- -------- 

     /3/  Please see Exhibit D indicating  the  investment  manager of the Aries
          Trust and the investment  manager's  executive  officers and directors
          and providing information called for by Items 2-6 of this statement as
          to said  investment  manager and officers and directors.  Exhibit D is
          herein incorporated by reference.

     /4/  Please see Exhibit AD  indicating  the managing  member of Hawkins and
          providing the information called for by Items 2-6 of this statement as
          to  said  managing  member.  Exhibit  AD  is  herein  incorporated  by
          reference.


                               Page 9 of 20 Pages

<PAGE>

Agreement  provides that if a Note were not paid in full at maturity or upon the
occurrence  of an Event of Default  referred  to in  Section 7 of the Notes,  in
addition to other  available  remedies,  the lesser of (i) the  then-outstanding
principal  amount of such Note or (ii) 10% of the original  principal  amount of
such Note would be convertible  into a number of shares of Common Stock equal to
the  amount  converted  divided  by $.001.  The  shares of Series D  Convertible
Preferred  Stock  initially  convertible  upon  conversion  of  the  Notes  were
initially  convertible  into 2,000,000 shares of Common Stock of the Issuer at a
conversion  price  equal  to $3.00  per  share  (as  adjusted  for the  Issuer's
one-for-ten reverse stock split effected on April 4, 1997 (the "Split")) subject
to adjustment upon the occurrence of certain events.  Additionally,  on February
13, 1997,  Aries Domestic  acquired (a) Class A Bridge Warrants for the purchase
of 273,000  shares of Common  Stock of the Issuer at an exercise  price equal to
$.01 per share (as adjusted  for the Split) and (b) Class B Bridge  Warrants for
the  purchase  of 427,000  shares of Common  Stock of the Issuer at an  exercise
price  equal to $5.50 (as  adjusted  for the split)  per share.  The Class A and
Class B Bridge Warrants were exchangeable,  and were eventually  exchanged,  for
New Warrants (as detailed  below) under certain  circumstances.  The Aries Trust
acquired  (a) Class A Bridge  Warrants  for the  purchase  of 507,000  shares of
Common  Stock of the  Issuer at an  exercise  price  equal to $.01 per share (as
adjusted  for the Split) and (b) Class B Bridge  Warrants  for the  purchase  of
793,000 shares of Common Stock of the Issuer at an exercise price equal to $5.50
per share (as adjusted for the Split).  In addition to the  foregoing,  prior to
February 13, 1997 the Aries Reporting  Persons acquired a total of 91,500 shares
(as adjusted for the Split) of Common Stock ("Purchased  Common  Stock") in
open market transactions. See Item 5.

         Pursuant to an Amended and Restated Amendment Agreement (the "Amendment
Agreement")  filed as Exhibit Q hereto,  Aries  Trust,  Aries  Domestic  and the
Issuer, inter alia, (i) agreed to postpone the maturity date of the Notes to the
earlier of (x)  December  31,  1997 and (y) the date of any  decision,  order or
other  determination  adverse to the Issuer or any of its directors by any court
or other tribunal in any lawsuit or other  proceeding  against the Issuer and/or
any of its directors by any of the Issuer's preferred stockholders,  (ii) agreed
that if Aries  Trust and Aries  Domestic  purchased  securities  in the  Private
Placement (as defined below), then Aries Trust and Aries Domestic would not vote
or dispose of such securities or convert any such  securities  into, or exercise
any such securities for, any shares of Common Stock of the Issuer,  for a period
of 90 days from the date of such purchase, (iii) changed the stated value of the
Series D  Preferred  Stock from ten  dollars  ($10.00)  per share to one hundred
dollars  ($100.00) per share,  and the  conversion  price of the Notes from five
dollars  ($5.00) to fifty  dollars  ($50.00) per share,  in each case subject to
adjustment  upon the occurrence of certain events and (iv) exchanged the Class A
and Class B Bridge  Warrants  for New Warrants in the forms filed as Exhibits T,
U, V and W  hereto.  The  New  Warrants  are  exercisable  for an  aggregate  of
6,357,616  shares of Common Stock at an exercise  price of $0.471875  per share,
subject to adjustment upon certain events.

         On May 29, 1997,  Aries Trust and Aries  Domestic each delivered to the
Issuer an  Irrevocable  Notice of  Conversion  pursuant to which Aries Trust and
Aries Domestic  converted  $422,500 and $227,500  principal  amount of the Notes
into  8,450 and  4,550  shares of Series D  Preferred  Stock,  respectively.  On
December 31, 1997 Aries Trust and Aries Domestic each converted the  outstanding
$1,703,488 and $917,263  aggregate  principal and interest amount of their Notes
into 34,070 and 18,345 shares of Series D Preferred Stock, respectively.


                               Page 10 of 20 Pages

<PAGE>

         On June 30,  1997,  the  Issuer  concluded  a  private  placement  (the
"Private  Placement") of its securities for which Paramount Capital,  Inc. acted
as placement agent in  consideration  for certain cash success fees and warrants
(the  "Placement  Warrants")  to  purchase up to 80,790  Class D Warrants  (each
"Class D Warrant"  being a warrant  to  purchase  one share of Common  Stock for
$.94375 at any time until June 30, 2002) and 16,158 shares of Series D Preferred
Stock, in each case subject to adjustment upon the occurrence of certain events,
for an aggregate of $1,777,380. Aries Domestic and Aries Trust used $304,500 and
$565,500 of their respective general funds to purchase  securities of the Issuer
in such private placement consisting, respectively, of 3,500 and 6,500 shares of
Series D  Preferred  Stock and  17,500 and  32,500  Class D  Warrants  which are
currently  convertible  for 370,861 and 688,742 and  exercisable  for 17,500 and
32,500  shares of Common  Stock of the  Issuer,  respectively.  Mr.  Weiss  used
$15,000  of his  personal  funds to  purchase  securities  of the Issuer in such
private  placement  consisting of 150 shares of Series D Preferred Stock and 750
Class D Warrants which are currently  convertible and exercisable for 15,894 and
750 shares of Common Stock of the Issuer, respectively.  Paramount Capital, Inc.
and the Issuer have entered an agreement, pursuant to which, in consideration of
Paramount Capital,  Inc.'s services as a financial  advisor,  Paramount Capital,
Inc.'s designees  received,  inter alia,  warrants (the "Advisory  Warrants") to
purchase up to an  aggregate of 121,185  Class D Warrants  and 24,237  shares of
Series D Preferred Stock, in each case subject to adjustment upon the occurrence
of certain events,  for an aggregate of $2,666,070.  The Placement  Warrants are
exercisable  between  December  31, 1997 and  December 30, 2007 and the Advisory
Warrants are  exercisable  between  December 31, 1998 and December 30, 2007.  On
December 29, 1997, PCI designated recipients (the "Paramount Warrant Designees")
of the Placement  Warrants and Advisory  Warrants.  Aries Trust, Aries Domestic,
Dr. Rosenwald  Mr.Weiss and Hawkins were among the Paramount  Warrant  Designees
and each received such Placement Warrants and/or Advisory Warrants in connection
with the Private Placement for which PCI acted as placement agent.

         On December  2, 1997,  Aries Trust and Aries  Domestic  entered  into a
Letter Agreement  whereby they purchased an aggregate of 54,000 shares of Series
A  Convertible  Preferred  Stock,  par value $.001 per share (Series A Preferred
Stock) of the  Issuer  from  various  holders  thereof.  Each  share of Series A
Preferred  Stock,  together  with  accrued but unpaid  interest  thereon,  has a
liquidation value of $60.00. The Series A Preferred Stock is convertible, at the
option of the  holder,  into  Common  Stock at a  conversion  price of $8.27 per
share.  Aries Trust used  $261,986.30  of its general  funds to purchase  36,000
shares of Series A Preferred  Stock,  which shares are convertible  into 261,185
shares of Common Stock.  Aries Domestic used $130,993.14 of its general funds to
purchase 18,000 shares of Series A Preferred Stock, which shares are convertible
into 130,593  shares of Common  Stock.  On July 27, 1998,  Aries Trust and Aries
Domestic entered into a Letter Agreement  whereby they purchased an aggregate of
40,000 shares of Series A Preferred Stock, from the holder thereof.  Aries Trust
used  $225,000  of its  general  funds to  purchase  30,000  shares  of Series A
Preferred  Stock,  which shares are  convertible  into 217,654  shares of Common
Stock.  Aries  Domestic  used  $75,000 of its general  funds to purchase  10,000
shares of Series A Preferred  Stock,  which shares are  convertible  into 72,551
shares of Common Stock.

         As of  November 1, 1998,  Dr.  Rosenwald,  Hawkins  and Michael  Weiss,
through  Hawkins,  may  be  deemed  the  beneficial  owners  of  the  securities
underlying the Advisory  Warrants which become  exerciseable  within 60 days of
November 1, 1998. Dr. Rosenwald acquired  beneficial  ownership of 1,951,801 and
92,101  shares of common  stock  issuable,  respectively,  upon  conversion  and
exercise of approximately 18,420 shares of Series D Preferred


                               Page 11 of 20 Pages

<PAGE>

Stock and Class D Warrants  issuable upon  conversion of the Advisory  Warrants.
Hawkins and Mr. Weiss,  through Hawkins,  each acquired beneficial  ownership of
502,993  and  23,735  shares  of  Common  Stock  issuable,   respectively,  upon
conversion  and  exercise of  approximately  4,747  shares of Series D Preferred
Stock and Class D Warrants issuable upon exercise of the Advisory Warrants.


         Between  August 19 and  October  30,  Aries  Trust  and Aries  Domestic
purchased  983,890 and 310,660  shares of Common  Stock  (additional  "Purchased
Common Stock"), respectively, on the open market. Aries Trust and Aries Domestic
used their respective general funds for such purchases.

         Aries Trust made the following purchases:

Date                       No. of Shares             Sales Price
- ----                       -------------             -----------
08/19/98                   17,800                    $0.625
08/20/98                   17,800                    $0.625
08/21/98                    2,000                    $0.688
08/24/98                   12,000                    $0.719
08/25/98                   11,100                    $0.730
08/27/98                   11,800                    $0.791
08/28/98                   11,900                    $0.813
08/31/98                   12,800                    $0.875
09/01/98                   12,800                    $0.939
09/02/98                   12,750                    $1.039
09/03/98                   12,770                    $1.000
09/04/98                   12,770                    $0.956
09/08/98                   18,900                    $1.017
09/09/98                   18,900                    $1.031
09/10/98                   18,900                    $0.957
09/11/98                   18,900                    $0.969
09/14/98                   21,100                    $0.969
09/15/98                   28,500                    $0.969
09/16/98                   20,000                    $0.969
09/17/98                   21,100                    $0.969
09/18/98                   21,100                    $0.991
09/21/98                   23,900                    $1.000
09/22/98                   24,000                    $1.000
09/23/98                   23,900                    $0.969
09/24/98                   24,000                    $0.969
09/25/98                   23,900                    $0.969
09/28/98                   32,000                    $0.938
09/29/98                   32,000                    $0.938
09/30/98                   24,300                    $0.969
10/01/98                   23,700                    $0.938
10/02/98                   23,700                    $0.938
10/05/98                   19,000                    $0.962


                               Page 12 of 20 Pages

<PAGE>

10/06/98                   19,000                    $0.938
10/07/98                   19,000                    $0.962
10/08/98                   57,500                    $0.969
10/09/98                   19,200                    $0.962
10/12/98                   18,100                    $0.969
10/13/98                   18,100                    $0.969
10/14/98                   18,100                    $0.988
10/15/98                   18,100                    $0.994
10/16/98                   18,100                    $0.997
10/19/98                   18,000                    $0.969
10/20/98                   18,000                    $0.969
10/21/98                   18,000                    $0.938
10/22/98                   18,000                    $0.963
10/23/98                   18,000                    $0.995
10/27/98                   15,700                    $0.938
10/28/98                   15,700                    $0.969
10/28/98                   15,600                    $0.938
10/29/98                   15,700                    $0.969
10/29/98                      200                    $0.938
10/30/98                   15,700                    $0.969

                  Aries Domestic made the following purchases:

Date                       No. of Shares            Sales Price
- ----                       -------------            -----------
08/19/98                    6,200                    $0.625
08/20/98                    6,200                    $0.625
08/24/98                    4,000                    $0.719
08/25/98                    3,900                    $0.730
08/27/98                    4,200                    $0.791
08/28/98                    4,100                    $0.813
08/31/98                    4,450                    $0.875
09/01/98                    4,450                    $0.939
09/02/98                    4,500                    $1.039
09/03/98                    4,480                    $1.000
09/04/98                    4,480                    $0.956
09/08/98                    6,600                    $1.017
09/09/98                    6,600                    $1.031
09/10/98                    6,600                    $0.957
09/11/98                    6,600                    $0.969
09/14/98                    7,400                    $0.969
09/16/98                    8,500                    $0.969
09/17/98                    7,400                    $0.969
09/18/98                    7,400                    $0.991
09/21/98                    8,400                    $1.000
09/22/98                    8,300                    $1.000
09/23/98                    8,400                    $0.969


                               Page 13 of 20 Pages

<PAGE>

09/24/98                    8,300                    $0.969
09/25/98                    8,400                    $0.969
09/30/98                    8,000                    $0.969
10/01/98                    8,300                    $0.938
10/02/98                    8,300                    $0.938
10/05/98                    6,600                    $0.962
10/06/98                    6,600                    $0.938
10/07/98                    6,600                    $0.962
10/08/98                   20,100                    $0.969
10/09/98                    6,400                    $0.962
10/12/98                    6,300                    $0.969
10/13/98                    6,300                    $0.969
10/14/98                    6,300                    $0.988
10/15/98                    6,300                    $0.994
10/19/98                    6,200                    $0.969
10/20/98                    6,200                    $0.969
10/21/98                    6,200                    $0.938
10/22/98                    6,200                    $0.963
10/27/98                    5,500                    $0.938
10/28/98                    5,500                    $0.938
10/28/98                    5,400                    $0.938
10/29/98                    5,500                    $0.969
10/30/98                    5,500                    $0.969
                                            
         Finally,  on October 30, 1998,  Aries Trust acquired  39,205 shares and
Aries Domestic acquired 13,775 shares of Common Stock in a private placement.

         The Filing  Persons  disclaim  beneficial  ownership  of all the Common
Stock  except the  Purchased  Common  Stock.  Mr.  Weiss,  Hawkins and the Aries
Reporting Persons each disclaim  beneficial  ownership of the securities held by
each other.

Item 4. Purpose of Transaction.

         The Filing Persons  acquired  securities of the Issuer as an investment
in the Issuer.  Except as indicated  in this  Schedule  13D, the Filing  Persons
currently  have no plans or proposals that relate to, or would result in, any of
the matters  described  in  subparagraphs  (a) through (j) of Item 4 of Schedule
13D.  Pursuant to Section 7.20 of the Note and Warrant Purchase  Agreement,  the
Aries  Reporting  Persons have the right to designate  nominees  constituting  a
majority of the members of the Board of  Directors  of the Issuer.  In May 1997,
Thomas H. Adams resigned from the Board of Directors of the Issuer,  on which he
had  served as  Chairman  of the  Board of  Directors,  and the Aries  Reporting
Persons  designated  Mr. Weiss as a nominee for Director and he was appointed by
the Board and elected Interim Chairman of the Issuer's Board of Directors. David
R. Walner, an Associate  Director of PCI and an Associate Director and Secretary
of Paramount Capital,  was appointed  Secretary of the Issuer on May 5, 1997. On
September 11, 1997,  the Aries  Reporting  Persons  designated  Glenn L. Cooper,
M.D.,  Donald G. Drapkin,  Bobby W. Sandage,  Jr.,  Ph.D. and Andrew J. Stein as
nominees to the Board of  Directors  of the Company  (the  "Board").  Mr.  Weiss
stepped down as Interim  Chairman and the Board elected Mr. Drapkin Chairman and
Mr. Weiss Vice  Chairman.  On  September  21,  1997,  Dr.  Kenneth G. Kasses was
elected to the Issuer's Board


                               Page 14 of 20 Pages

<PAGE>

of Directors, and Dr. Kasses was appointed President and Chief Executive Officer
of the Issuer,  effective October 1, 1997.  Effective October 6, 1998, Donald G.
Drapkin  resigned as Chairman of the Board and Dr. Kasses was elected to replace
him as  Chairman.  In  connection  with the Loans and the  related  transactions
(collectively,  the  "Transactions"),  the Issuer amended its Shareholder Rights
Agreement  (the  "Plan")  dated as of October 1, 1993,  to provide that the Plan
would not be applicable  to the Aries  Reporting  Persons and the  Transactions.
Aries Trust and Aries Domestic  entered into a Line of Credit Agreement with the
Issuer pursuant to which Aries Trust and Aries Domestic provided the Issuer with
a  line  of  credit  of  up to  $500,000,  which  subsequently  was  repaid,  in
consideration for warrants (the "Line of Credit Warrants") in the forms filed as
Exhibits N and O hereto, to purchase 50,000 shares of Common Stock of the Issuer
exercisable  at $2.50 per share,  subject to adjustment  upon the  occurrence of
certain events. The Filing Persons may from time to time acquire, or dispose of,
Common  Stock  and/or  other  securities  of the Issuer if and when they deem it
appropriate. The Filing Persons may formulate other purposes, plans or proposals
relating to any of such securities of the Issuer to the extent deemed  advisable
in light of market conditions, investment policies and other factors.

Item 5.Interest in Securities of Issuer.

     (a)  As of November 1, 1998:  Dr.  Rosenwald,  as the sole  shareholder  of
          Paramount Capital and as the holder of Placement Warrants and Advisory
          Warrants, may be deemed beneficially to own 19,583,252 shares or 72.8%
          of  the  Issuer's  Common  Stock;   Paramount  Capital,   through  the
          acquisitions of securities by Aries Trust and Aries  Domestic,  may be
          deemed  beneficially to own 16,716,858 shares or 69.5% of the Issuer's
          Common Stock;  and Mr. Weiss, as Managing Member of Hawkins and as the
          holder of securities of the Issuer,  may be deemed to beneficially own
          675,064 shares or 7.1% of the Issuer's  Common Stock.  Aries Domestic,
          Aries  Trust  and  Hawkins  may be  deemed  beneficially  to  own  the
          following numbers of shares of Common Stock:


          Aries Domestic       5,660,284
          Aries Trust         11,056,575
          Hawkins                526,737

          Pursuant to Rule 13d-4 promulgated  under the Securities  Exchange Act
          of 1934, as amended,  the Filing Persons disclaim beneficial ownership
          of all the Common Stock except the Purchased Common Stock. Pursuant to
          Rule 13d-4 promulgated  under the Securities  Exchange Act of 1934, as
          amended,  the Aries  Reporting  Persons,  Mr.  Weiss and Hawkins  each
          disclaim beneficial ownership of the securities held by each other.

          The  outstanding  shares of Series D Preferred Stock of the Issuer are
          entitled  to vote  together  with the  holders of Common  Stock on all
          matters  submitted  to a vote of  stockholders  of the  Issuer.  As of
          November 1, 1998,  Dr.  Rosenwald and Paramount  Capital may be deemed
          beneficially  to own  (within  the  meaning  of Rule  13d-3  under the
          Securities   Exchange  Act  of  1934,  as  amended)  48.5%  and 44.5%,
          respectively, of the


                               Page 15 of 20 Pages

<PAGE>

          aggregate  voting  power of the Common  Stock and  Series D  Preferred
          Stock outstanding.

     (b)  Dr.  Rosenwald  and  Paramount  Capital  share the power to vote or to
          direct the vote and to dispose or to direct the  disposition  of those
          shares owned by each of Aries Domestic and Aries Trust.  Dr. Rosenwald
          has the sole  power to vote or to direct the vote and to dispose or to
          direct the disposition of the shares underlying the Placement Warrants
          and Advisory  Warrants  held by him.  Mr. Weiss and Hawkins  share the
          power to vote or to direct  the vote and to  dispose  or to direct the
          disposition  of the shares  owned by Hawkins.  Mr.  Weiss has the sole
          power to vote or to direct  the vote and to  dispose  or to direct the
          disposition of the shares that he owns.

     (c)  Other than certain of the open market and private placement  purchases
          of Common  Stock  reported in Item 3, the  Reporting  Persons have not
          engaged in any  transactions  in the Common Stock of the Issuer in the
          past 60 days.

     (d)&(e) Not applicable.

Item 6.   Contracts, Arrangements, Understandings or Relationships With Respect
          to Securities of the Issuer.

         Paramount  Capital is the  investment  manager  of Aries  Trust and the
General  Partner of Aries  Domestic and in such  capacities has the authority to
make  certain  investment  decisions  on  behalf  of  such  entities,  including
decisions  relating to the  securities  of the Issuer.  In  connection  with its
investment management duties, Paramount Capital receives certain management fees
and performance  allocations from Aries Trust and Aries Domestic.  Dr. Rosenwald
is the sole shareholder of Paramount Capital. Additionally, on January 28, 1997,
the Issuer entered into a Letter of Intent with Paramount Capital, Inc. pursuant
to which it was contemplated that Paramount Capital, Inc. would act as financial
advisor and investment banker for the Issuer in future capital raising and other
strategic  transactions for the Issuer.  Dr.  Rosenwald is the chairman and sole
shareholder of Paramount Capital,  Inc. On June 30, 1997, the Issuer concluded a
private placement of its securities for which Paramount  Capital,  Inc. acted as
placement  agent in  consideration  for certain cash success fees and  Placement
Warrants (see Item 3). In addition,  Paramount Capital, Inc. and the Issuer have
entered an agreement,  pursuant to which, in consideration of Paramount Capital,
Inc.'s services as a financial advisor, Paramount Capital, Inc.'s designees have
received,  inter alia,  Advisory  Warrants (see Item 3). On June 6, 1997,  Aries
Trust and Aries Domestic entered into a Line of Credit Agreement with the Issuer
pursuant to which Aries Trust and Aries Domestic advanced a line of credit of up
to  $500,000  in  consideration  of the Line of  Credit  Warrants  (see Item 4).
Certain directors and officers of Paramount Capital and Paramount Capital,  Inc.
are now also directors and/or officers of the Issuer (see Item 4).

         Except as indicated in this Schedule 13D and the exhibits hereto, there
is no contract,  arrangement,  understanding or relationship  between the Filing
Persons and any other person, with respect to any securities of the Issuer.


                               Page 16 of 20 Pages


<PAGE>

Item 7. Material to be Filed as Exhibits.


         Exhibit A/1/:              Agreement of Joint Filing of Schedule 13d 
                                    dated as of February 13, 1997.

         Exhibit B/6/:              List of executive officers and directors
                                    of Paramount Capital and information  called
                                    for by Items 2-6 of this statement  relating
                                    to said officers and directors.

         Exhibit C/1/:              List of executive officers and directors
                                    of Aries Domestic and information called for
                                    by items 2-6 of this  statement  relating to
                                    said officers and directors.

         Exhibit D/1/:              List of executive officers and directors
                                    of Aries Trust and information called for by
                                    items 2-6 of this statement relating to said
                                    officers and directors.

         Exhibit E/1/:              Notes and Warrant Purchase Agreement dated 
                                    as of January 28, 1997.

         Exhibit F/1/:              Senior Convertible Bridge Note for 
                                    $1,050,000 issued to Aires Domestic 
                                    dated January 28, 1997.

         Exhibit G/1/:              Senior Secured Convertible Bridge Note for 
                                    $1,950,000 issued to Aries Trust dated 
                                    January 28, 1997.

         Exhibit H/1/:              Class A Bridge  Warrant for the purchase
                                    of  2,730,000  shares of Common Stock issued
                                    to Aries Domestic dated January 28, 1997.

         Exhibit I/1/:              Class A Bridge  Warrant for the purchase
                                    of  5,070,000  shares if Common Stock issued
                                    to Aries domestic dated January 28, 1997.


         Exhibit J/1/:              Class B Bridge  Warrant for the Purchase
                                    of  4,270,000  shares of Common Stock issued
                                    to Aries domestic dated January 28, 1997.

         Exhibit K/1/:              Class B Bridge Warrant for the Purchase of 
                                    7,930,000 shares of Common Stock issued to 
                                    Aries Trust dated January 28, 1997.

         Exhibit L/1/:              Letter of Intent dated January 28, 1997.

         Exhibit M/2/:              Agreement of Joint Filing of Schedule 13D.

         Exhibit N/2/:              Warrant for the purchase of 32,500 shares of
                                    Common Stock of the Issuer, issued to Aries 
                                    Trust pursuant to the


                               Page 17 of 20 Pages

<PAGE>



                                    Senior Secured Line of Credit Agreement 
                                    between the Issuer, Aries Trust and Aries 
                                    Domestic.

         Exhibit O/2/:              Warrant  for  the  purchase  of
                                    17,500 shares of Common Stock of the
                                    Issuer,  issued  to  Aries  Domestic
                                    pursuant to the Senior  Secured Line
                                    of  Credit  Agreement   between  the
                                    Issuer,   Aries   Trust   and  Aries
                                    Domestic.

         Exhibit P/2/:              Amended Certificate of Designation for 
                                    Series D Convertible Preferred Stock of 
                                    Genta Incorporated.

         Exhibit Q/2/:              Amended and Restated Amendment Agreement 
                                    between the Issuer, Aries Trust and Aries 
                                    Domestic.

         Exhibit R/2/:              Amended and Restated Senior Secured 
                                    Convertible Bridge Note for $1,050,000 
                                    issued to Aries Domestic.

         Exhibit S/2/:              Amended and Restated Senior Secured 
                                    Convertible Bridge Note for 
                                    $1,950,000 issued to Aries Trust.

         Exhibit T/2/:              New Class A Bridge Warrant for the Purchase 
                                    of 350,000 shares of Common Stock issued to 
                                    Aries Domestic.

         Exhibit U/2/:              New Class A Bridge Warrant for the Purchase 
                                    of 650,000 shares of Common Stock issued 
                                    to Aries Trust.

         Exhibit V/2/:              New Class B Bridge Warrant for the Purchase 
                                    of 350,000 shares of Common Stock issued to 
                                    Aries Domestic.

         Exhibit W/2/:              New Class B Bridge Warrant for the Purchase 
                                    of 650,000 shares of Common Stock issued to 
                                    Aries Trust.

         Exhibit X/3/:              Agreement of Joint Filing of Schedule 13D 
                                    dated as of November 5, 1993.

         Exhibit Y/3/:              List of  executive  officers and
                                    directors  of  PCI  and  information
                                    called  for by  Items  2-6  of  this
                                    statement  relating to said officers
                                    and directors.

         Exhibit Z/4/               Letter  Agreement  between Aries Trust,
                                    mestic and third parties relating to
                                    hase of Series A Preferred Stock.

         Exhibit AA/5/:             Agreement of Joint Filing of Schedule 13D 
                                    dated as of July 31, 1998.

         Exhibit AB/5/:             Letter Agreement between Aries Trust, Aries 
                                    Domestic and Highbridge Capital Corporation 
                                    relating to the purchase of Series A 
                                    Preferred Stock.


                                  Page 18 of 20 Pages

<PAGE>


         Exhibit AC/6/:             Agreement of Joint Filing of schedule 13D 
                                    dated as of November 4, 1998.

         Exhibit AD/6/:             List  of  managing  members  of  Hawkins
                                    and  information  called  for  by
                                    Items 2-6 of this statement  relating to
                                    said managing members.

         (1)  Exhibits  A, C,  D,  E,  F, G, H, I, J, K and L were  filed  on
February 24, 1997 with the original Schedule.

         (2)  Exhibits M, N, O, P, Q, R, S, T, U, V and W were filed on July 28,
1997,  with  Amendment  No. 1 to the  Schedule.

         (3) Exhibits X and Y were filed on November 7, 1997 with  Amendment No.
4 to the Schedule.

         (4) Exhibit Z was filed on December 31, 1997,  with  Amendment No. 4 to
the Schedule.

         (5) Exhibits AA and AB were filed on August 5, 1998 with  Amendment No.
5 to the original Schedule.

         (6) Exhibits B, AC, and AD are filed herewith.


                               Page 19 of 20 Pages

<PAGE>

                                   SIGNATURES

         After  reasonable  inquiry and to the best  knowledge and belief of the
undersigned,  the  undersigned  certify that the  information  set forth in this
statement is true, complete and correct.

                                   PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.    
                                                                               
Dated:   November 4, 1998                                                     
         New York, NY              By: /s/ Lindsay A. Rosenwald                
                                       --------------------------------------- 
                                       Lindsay A. Rosenwald, M.D.              

                                                                               
                                   ARIES DOMESTIC FUND, L.P.                   
                                   By: Paramount Capital Asset Management, Inc.
                                   General Partner                             
Dated:   November 4, 1998                                                     
         New York, NY              By: /s/ Lindsay A. Rosenwald                
                                       --------------------------------------- 
                                       Lindsay A. Rosenwald, M.D.              

                                                                               
                                                                               
                                   THE ARIES TRUST                             
                                   By: Paramount Capital Asset Management, Inc.
Dated:   November 4, 1998         General Partner                             
         New York, NY              
                                   By: /s/ Lindsay A. Rosenwald                
                                       --------------------------------------- 
                                       Lindsay A. Rosenwald, M.D.              

                                   
                                   
Dated:   November 4, 1998         /s/ Lindsay A. Rosenwald                   
         New York, NY              ---------------------------------------     
                                        Lindsay A. Rosenwald, M.D.             
                                                                               
                                    
Dated:   November 4, 1998          /s/ Michael S. Weiss                   
         New York, NY               ---------------------------------------    
                                        Mr. Michael S. Weiss                  
                                                                               
                                                                               
                                  HAWKINS GROUP, LLC 


Dated:   November 4, 1998        
         New York, NY             By: /s/ Michael S. Weiss 
                                      ---------------------------------------
                                          Mr. Michael S. Weiss
                                          Managing Member             

                               Page 20 of 20 Pages


<PAGE>
                                                     EXHIBIT B

         The name and principal occupation or employment, which in each instance
is with Paramount Capital Asset Management,  Inc. ("Paramount  Capital") located
at 787 Seventh Avenue,  48th Floor, New York, New York, 10019, of each executive
officer and director of Paramount Capital is as follows:

<TABLE>
<CAPTION>

                                                                       PRINCIPAL OCCUPATION
         NAME                                                          OR EMPLOYMENT
         ----                                                          -------------
<S>                                                              <C>    


Lindsay A. Rosenwald, M.D.                                             Chairman of the Board of Paramount
                                                                       Capital Asset Management, Inc.,
                                                                       Paramount Capital Investments LLC
                                                                       and Paramount Capital, Inc.

Mark C. Rogers, M.D.                                                   President of Paramount Capital Asset
                                                                       Management, Inc., Paramount
                                                                       Capital Investments LLC and
                                                                       Paramount Capital, Inc.

Peter Morgan Kash
                                                                       Director of Paramount Capital
                                                                       Asset Management, Inc.,
                                                                       Inc., Senior Managing
                                                                       Director,  Paramount Capital,
                                                                       Inc.

Dr. Yuichi Iwaki                                                       Director of Paramount Capital Asset
                                                                       Management, Inc., Inc., Professor,
                                                                       University of Southern California
                                                                       School of Medicine
</TABLE>


Item 2.

         During  the five  years  prior to the date  hereof,  none of the  above
persons  (to the best of  Paramount  Capital's  knowledge)  was  convicted  in a
criminal  proceeding  (excluding traffic violations or similar  misdemeanors) or
was a party  to a civil  proceeding  of a  judicial  or  administrative  body of
competent jurisdiction,  as a result of which such person was or is subject to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, Federal or State securities laws or finding
any violation with respect to such laws.

Items 3-6.

         Please refer to Items 3-6 herein reporting the beneficial ownership.

<PAGE>

                                   EXHIBIT AC

                                    AGREEMENT

                          JOINT FILING OF SCHEDULE 13D


         The  undersigned   hereby  agree  jointly  to  prepare  and  file  with
regulatory  authorities  a  Schedule  13D  and  any  future  amendments  thereto
reporting   each  of  the   undersigned's   ownership  of  securities  of  Genta
Incorporated  and hereby  affirm that such Schedule 13D is being filed on behalf
of each of the undersigned.

                                 PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   November 4, 1998
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.


                                 ARIES DOMESTIC FUND, L.P.
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   November 4, 1998
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.



                                 THE ARIES TRUST
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   November 4, 1998
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.



Dated:   November 4, 1998
         New York, NY                 /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.


Dated:   November 4, 1998
         New York, NY                 /s/ Michael S. Weiss
                                     ---------------------------------------
                                     Mr. Michael S. Weiss


                                  HAWKINS GROUP, LLC

Dated:   November 4, 1998                                  
         New York, NY             By: /s/ Michael S. Weiss                   
                                     --------------------------------------- 
                                     Mr. Michael S. Weiss                    
                                     Managing Member                         
                                                                             

<PAGE>


                                   EXHIBIT AD

         The name and principal  occupation or employment of the Managing Member
of  Hawkins,which  is located at 787 Seventh Avenue,  44th Floor,  New York, NY,
10019, is as follows:

         NAME                                  PRINCIPAL OCCUPATION
                                               OR EMPLOYMENT

Michael S. Weiss                               (See Item 2(c) of the Schedule)


Item 2.

         During the five years prior to the date  hereof,  the above  person has
not been convicted in a criminal  proceeding  (excluding  traffic  violations or
similar misdemeanors) and was not a party to a civil proceeding of a judicial or
administrative body of competent jurisdiction,  as a result of which such person
was or is  subject  to a  judgment,  decree  or  final  order  enjoining  future
violations  of, or prohibiting  or mandating  activities  subject to, Federal or
State securities laws or finding any such violations with respect to such laws.

Items 3-6

         Please  refer to Items 3-6 of the  Schedule  reporting  the  beneficial
ownership.




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