GENTA INCORPORATED /DE/
SC 13D/A, 1999-01-05
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                              AMENDED SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 11)*

                               Genta Incorporated
                               ------------------
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
                     ---------------------------------------
                         (Title of Class of Securities)

                                  372 45 M 20 7
                                  -------------
                                 (CUSIP Number)

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:
Michael S. Weiss                                   Monica C. Lord, Esq.
Paramount Capital Asset                            Kramer Levin
   Management, Inc.                                  Naftalis & Frankel LLP
787 Seventh Avenue                                 919 Third Avenue
New York, NY 10019                                 New York, NY  10022
(212) 554-4372                                     (212) 715-9100

(Name, Address and Telephone Number of Person Authorized to Receive Notices and 
Communications)

                                December 28, 1998
                                -----------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:
   |_|

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                               Page 1 of 11 Pages




<PAGE>

<TABLE>
<CAPTION>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                            Page 2 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
<S>                                                                             <C>    

     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              Paramount Capital Asset Management, Inc.
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     |_|

- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              OO (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              Delaware

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            None
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    18,421,289
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    None
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    18,421,289
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              18,421,289
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              72.2% (48.3% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON*
              CO
- -----------------------------------------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of December 28, 1998,  Paramount Capital
Asset Management,  Inc. may be deemed beneficially to own (within the meaning of
Rule 13d-3 under the  Securities  Exchange Act of 1934, as amended) 48.3% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.




<PAGE>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                          Page 3 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              Aries Domestic Fund, L.P.
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     |_|

- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              OO (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              Delaware

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            None
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    6,091,816
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    None
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    6,091,816
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              6,091,816
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              40.7% (18.6% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON*
              PN
- -----------------------------------------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of December 28, 1998, the Aries Domestic
Fund,  L.P. may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934, as amended)  18.6% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.





<PAGE>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                          Page 4 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              The Aries Trust
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     |_|
- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              OO (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              Cayman Islands

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            None
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    12,329,472
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    None
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    12,329,472
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              12,329,472
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              61.6% (34.8% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON* OO (see Item 2)
- -----------------------------------------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer. As of December 28, 1998, The Aries Trust may
be deemed  beneficially  to own  (within  the  meaning of Rule  13d-3  under the
Securities Exchange Act of 1934, as amended) 34.8% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.




<PAGE>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                          Page 5 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              Lindsay A. Rosenwald, M.D.
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     |_|
- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              OO (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              United States

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            2,866,393**
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    18,421,289
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    2,866,393**
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    18,421,289
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              21,287,682**
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              75.0% (51.9% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON*
              IN
- -----------------------------------------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the  Issuer.  As of  December  28,  1998,  Lindsay  A.
Rosenwald,  M.D. may be deemed  beneficially  to own (within the meaning of Rule
13d-3  under the  Securities  Exchange  Act of 1934,  as  amended)  51.9% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.




<PAGE>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                          Page 6 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              Hawkins Group, LLC
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     [x]
- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              OO (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              United States

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            None
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    526,737
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    None
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    526,737
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              526,737
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              5.3% (1.7% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON* OO (See Item 2)
- -----------------------------------------------------------------------------------------------------------------

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the Issuer.  As of December 28, 1998,  Mr.  Michael S.
Weiss may be deemed  beneficially to own (within the meaning of Rule 13d-3 under
the  Securities  Exchange Act of 1934, as amended) 1.7% of the aggregate  voting
power of the Common Stock and Series D Preferred Stock outstanding.




<PAGE>

- --------------------------------------                                   ----------------------------------------
      CUSIP No. 372 45 M 20 7                          13D                          Page 7 of 11 Pages
- --------------------------------------                                   ----------------------------------------

- -----------------------------------------------------------------------------------------------------------------
     1        NAMES OF REPORTING PERSONS
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

              Mr. Michael S. Weiss
- -----------------------------------------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                        (a)     |_|
                                                                                      (b)     [x]
- -----------------------------------------------------------------------------------------------------------------
     3        SEC USE ONLY

- -----------------------------------------------------------------------------------------------------------------
     4        SOURCE OF FUNDS*

              PF (see Item 3)
- -----------------------------------------------------------------------------------------------------------------
     5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
              ITEM 2(d) or 2(e)
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
     6        CITIZENSHIP OR PLACE OF ORGANIZATION

              United States

- -------------------------------------------------------------------------------------------------------------------
             NUMBER OF                      7       SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            148,327
              OWNED BY
                EACH
             REPORTING
               PERSON
                WITH
                                     ------------------------------------------------------------------------------
                                            8       SHARED VOTING POWER

                                                    526,737
                                     ------------------------------------------------------------------------------
                                            9       SOLE DISPOSITIVE POWER

                                                    148,327
                                     ------------------------------------------------------------------------------
                                           10       SHARED DISPOSITIVE POWER

                                                    526,737
- -------------------------------------------------------------------------------------------------------------------

    11        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              675,064
- -----------------------------------------------------------------------------------------------------------------
    12        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                                              |_|
- -----------------------------------------------------------------------------------------------------------------
    13        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

              6.7%(2.2% of the outstanding voting power)**
- -----------------------------------------------------------------------------------------------------------------
    14        TYPE OF REPORTING PERSON*
              IN
- -----------------------------------------------------------------------------------------------------------------

</TABLE>

** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of  stockholders  of the Issuer.  As of December 28, 1998,  Mr.  Michael S.
Weiss may be deemed  beneficially to own (within the meaning of Rule 13d-3 under
the  Securities  Exchange Act of 1934, as amended) 2.2% of the aggregate  voting
power of the Common Stock and Series D Preferred Stock outstanding.




<PAGE>

                                         SCHEDULE 13D

               This Amendment No. 11 amends and  supplements the following items
of the Reporting Persons' Statement on Schedule 13D, dated February 24, 1997, as
amended to date (the "Schedule").

Item 3.        Source and Amount of Funds or Other Consideration

               The  information  contained  in Item 3 to the  Schedule is hereby
amended by adding the following:

               Between  December 11 and December 28, 1998, Aries Trust and Aries
Domestic  used their  respective  general  funds to purchase  201,557 and 72,014
shares of Common Stock (additional "Purchased Common Stock"),  respectively,  on
the open market.

                    Aries Trust made the following purchases:

Date                   No. of Shares               Sales Price
- ----                   -------------               -----------

12/11/98               16,000                      $1.219
12/14/98               40,457                      $1.327
12/15/98               14,800                      $1.297
12/16/98               20,300                      $1.313
12/17/98               19,800                      $1.301
12/18/98                7,400                      $1.313
12/21/98                9,000                      $1.313
12/22/98               27,200                      $1.296
12/28/98               46,600                      $1.224

                  Aries Domestic made the following purchases:

Date                  No. of Shares                Sales Price
- ----                  -------------                -----------

12/11/98               6,500                       $1.219
12/14/98              14,214                       $1.327
12/15/98               5,200                       $1.297
12/16/98               7,000                       $1.313
12/17/98               7,500                       $1.301
12/18/98               2,600                       $1.313
12/21/98               3,100                       $1.313
12/22/98               9,600                       $1.296
12/28/98              16,300                       $1.224




                               Page 8 of 11 Pages



<PAGE>

Item 5.        Interest in Securities of Issuer.

        The  information  contained in Item 5 to the Schedule is hereby  amended
and supplemented to read as follows:

               (a)  As  of  December  28,  1998:  Dr.  Rosenwald,  as  the  sole
                    shareholder  of  Paramount  Capital  and  as the  holder  of
                    Placement  Warrants  and  Advisory  Warrants,  may be deemed
                    beneficially  to  own  21,287,682  shares  or  75.0%  of the
                    Issuer's  Common  Stock;  Paramount  Capital,   through  the
                    acquisitions   of   securities  by  Aries  Trust  and  Aries
                    Domestic,  may be  deemed  beneficially  to  own  18,421,289
                    shares or 72.2% of the Issuer's Common Stock; and Mr. Weiss,
                    as  Managing   Member  of  Hawkins  and  as  the  holder  of
                    securities of the Issuer,  may be deemed to beneficially own
                    675,064 shares or 6.7% of the Issuer's  Common Stock.  Aries
                    Domestic, Aries Trust and Hawkins may be deemed beneficially
                    to own the following numbers of shares of Common Stock:

                    Aries Domestic                  6,091,816
                    Aries Trust                    12,329,472
                    Hawkins                           526,737

                    Pursuant  to Rule  13d-4  promulgated  under the  Securities
                    Exchange  Act  of  1934,  as  amended,  the  Filing  Persons
                    disclaim beneficial ownership of all the Common Stock except
                    the  Purchased   Common   Stock.   Pursuant  to  Rule  13d-4
                    promulgated  under the  Securities  Exchange Act of 1934, as
                    amended,  the Aries Reporting Persons, Mr. Weiss and Hawkins
                    each disclaim beneficial ownership of the securities held by
                    each other.

                    The  outstanding  shares of Series D Preferred  Stock of the
                    Issuer are  entitled  to vote  together  with the holders of
                    Common  Stock  on  all  matters   submitted  to  a  vote  of
                    stockholders  of the Issuer.  As of December 28,  1998,  Dr.
                    Rosenwald,  Paramount  Capital and Aries Trust may be deemed
                    beneficially  to own (within the meaning of Rule 13d-3 under
                    the  Securities  Exchange  Act of 1934,  as amended)  51.9%,
                    48.3% and 34.8%, respectively, of the aggregate voting power
                    of  the   Common   Stock  and  Series  D   Preferred   Stock
                    outstanding.

               (b)  Dr. Rosenwald and Paramount  Capital share the power to vote
                    or to  direct  the  vote and to  dispose  or to  direct  the
                    disposition  of those shares owned by each of Aries Domestic
                    and Aries Trust. Dr. Rosenwald has the sole power to vote or
                    to  direct  the  vote  and  to  dispose  or  to  direct  the
                    disposition of the shares underlying the Placement  Warrants
                    and  Advisory  Warrants  held by him.  Mr. Weiss and Hawkins
                    share the power to vote or to direct the vote and to dispose
                    or to direct the disposition of the shares owned by Hawkins.
                    Mr.  Weiss has the sole  power to vote or to direct the vote
                    and to dispose or to direct  the  disposition  of the shares
                    that he owns.

                               Page 9 of 11 Pages



<PAGE>

               (c)  Other than certain of the open market and private  placement
                    purchases of Common Stock  reported in Item 3, the Reporting
                    Persons have not engaged in any  transactions  in the Common
                    Stock of the Issuer in the past 60 days.

               (d)&(e)       Not applicable.


                               Page 10 of 11 Pages



<PAGE>

                                   SIGNATURES
                                   ----------

               After reasonable  inquiry and to the best knowledge and belief of
the undersigned,  the undersigned certify that the information set forth in this
statement is true, complete and correct.

                                    PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:  January 5, 1999
        New York, NY             By: 
                                     -------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     Chairman



                                    ARIES DOMESTIC FUND, L.P.
                                    By: Paramount Capital Asset Management, Inc.
                                          General Partner

Dated:  January 5, 1999
        New York, NY             By: /s/ Lindsay A. Rosenwald
                                     -------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     Chairman



                                    THE ARIES TRUST
                                    By: Paramount Capital Asset Management, Inc.
                                    Investment Manager

Dated:  January 5, 1999
        New York, NY             By: /s/ Lindsay A. Rosenwald
                                     -------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     Chairman



Dated:  January 5, 1999
        New York, NY             /s/ Lindsay A. Rosenwald
                                 ---------------------------------
                                 Lindsay A. Rosenwald, M.D.



Dated:  January 5, 1999
        New York, NY             /s/ Mr. Michael S. Weiss
                                 ---------------------------------
                                 Mr. Michael S. Weiss



                                    HAWKINS GROUP, LLC

Dated:  January 5, 1999
        New York, NY         By:  /s/ Mr. Michael S. Weiss
                                  ---------------------------------
                                  Mr. Michael S. Weiss
                                  Managing member


                               Page 11 of 11 Pages





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