GENTA INCORPORATED /DE/
SC 13D/A, 1999-03-12
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                              AMENDED SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 13)*

                               Genta Incorporated 
                               ------------------ 
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
                     ---------------------------------------
                         (Title of Class of Securities)

                                 372 45 M 20 7 
                                 ------------- 
                                 (CUSIP Number)

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:
Michael S. Weiss                                     Monica C. Lord, Esq.
Paramount Capital Asset                              Kramer Levin
   Management, Inc.                                  Naftalis & Frankel LLP
787 Seventh Avenue                                   919 Third Avenue
New York, NY 10019                                   New York, NY  10022
(212) 554-4372                                       (212) 715-9100

   (Name, Address and Telephone Number of Person Authorized to Receive Notices
                              and Communications)

                                  March 9, 1999
                               -------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:
   | |

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


                               Page 1 of 11 Pages




<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 2 of 11 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Paramount Capital Asset Management, Inc.
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|

- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER    
           REPORTING                                                           
             PERSON                                     20,445,050
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER 
                                                                               
                                                        None                   
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        20,445,050
- --------------------------------------------------------------------------------

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           20,445,050
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          67.0% (53.0% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON*
           CO
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of March 9, 1999,  Paramount  Capital
Asset Management,  Inc. may be deemed beneficially to own (within the meaning of
Rule 13d-3 under the  Securities  Exchange Act of 1934, as amended) 53.0% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.



<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 3 of 11 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Aries Domestic Fund, L.P.
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|

- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER     
           REPORTING                                                            
             PERSON                                     6,741,008
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        None
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        6,741,008
- --------------------------------------------------------------------------------
11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           6,741,008
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           34.1% (20.4% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON*
           PN
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders  of the Issuer.  As of March 9, 1999, the Aries Domestic
Fund,  L.P. may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934, as amended)  20.4% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>


- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 4 of 10 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
1          NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           The Aries Trust
- --------------------------------------------------------------------------------
2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)      |_|
                                                                    (b)      |_|
- --------------------------------------------------------------------------------
3          SEC USE ONLY

- --------------------------------------------------------------------------------
4          SOURCE OF FUNDS*

           OO (see Item 3)
- --------------------------------------------------------------------------------
5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
           ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Cayman Islands

- --------------------------------------------------------------------------------
           NUMBER OF                          7         SOLE VOTING POWER
             SHARES
          BENEFICIALLY                                  None
            OWNED BY                  ------------------------------------------
              EACH                            8         SHARED VOTING POWER     
           REPORTING                                                            
             PERSON                                     13,704,042
              WITH                    ------------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        None                    
                                      ------------------------------------------
                                             10         SHARED DISPOSITIVE POWER

                                                        13,704,042
- --------------------------------------------------------------------------------

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           13,704,042
- --------------------------------------------------------------------------------
12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           55.0% (38.3% of the outstanding voting power)**
- --------------------------------------------------------------------------------
14         TYPE OF REPORTING PERSON* OO (see Item 2)
- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of March 9, 1999, The Aries Trust may
be deemed  beneficially  to own  (within  the  meaning of Rule  13d-3  under the
Securities Exchange Act of 1934, as amended) 38.3% of the aggregate voting power
of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 5 of 10 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Lindsay A. Rosenwald, M.D.
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      |_|
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 OO (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                    7         SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            2,866,393**
                  OWNED BY                  ------------------------------------
                    EACH                      8         SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               20,445,050
                    WITH                    ------------------------------------
                                              9         SOLE DISPOSITIVE POWER  
                                                                                
                                                        2,866,393**
                                            ------------------------------------
                                             10         SHARED DISPOSITIVE POWER
                                                                                
                                                        20,445,050
- --------------------------------------------------------------------------------
      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 23,311,443**
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 69.8% (56.3% of the outstanding voting power)**
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON*
                 IN

- --------------------------------------------------------------------------------
** The outstanding shares of Series D Preferred Stock of the Issuer are entitled
to vote together with the holders of Common Stock on all matters  submitted to a
vote of stockholders of the Issuer.  As of March 9, 1999,  Lindsay A. Rosenwald,
M.D. may be deemed  beneficially  to own (within the meaning of Rule 13d-3 under
the Securities  Exchange Act of 1934, as amended) 56.3% of the aggregate  voting
power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 6 of 10 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Hawkins Group, LLC
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      [x]
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 OO (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                      7       SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            None
                  OWNED BY              ----------------------------------------
                    EACH                        8       SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               526,737
                    WITH                ----------------------------------------
                                                9       SOLE DISPOSITIVE POWER
                                                                              
                                                        None
                                        ----------------------------------------
                                               10       SHARED DISPOSITIVE POWER
                                                                              
                                                        526,737
- --------------------------------------------------------------------------------

      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 526,737
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 3.6% (1.7% of the outstanding voting power)***
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON*
                 OO (See Item 2)
- --------------------------------------------------------------------------------
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted to a vote of stockholders of the Issuer. As of March 9, 1999,  Hawkins
Group,  LLC may be deemed  beneficially to own (within the meaning of Rule 13d-3
under the  Securities  Exchange Act of 1934,  as amended)  1.7% of the aggregate
voting power of the Common Stock and Series D Preferred Stock outstanding.


<PAGE>

- --------------------------------------------------------------------------------
CUSIP No. 372 45 M 20 7                 13D                   Page 6 of 10 Pages
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------
      1          NAMES OF REPORTING PERSONS
                 S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                 Mr. Michael S. Weiss
- --------------------------------------------------------------------------------
      2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)      |_|
                                                                    (b)      [x]
- --------------------------------------------------------------------------------
      3          SEC USE ONLY

- --------------------------------------------------------------------------------
      4          SOURCE OF FUNDS*

                 PF (see Item 3)
- --------------------------------------------------------------------------------
      5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
                 PURSUANT TO ITEM 2(d) or 2(e)
                                                                             |-|
- --------------------------------------------------------------------------------
      6          CITIZENSHIP OR PLACE OF ORGANIZATION

                 United States
- --------------------------------------------------------------------------------
                 NUMBER OF                      7       SOLE VOTING POWER
                   SHARES
                BENEFICIALLY                            148,327
                  OWNED BY              ----------------------------------------
                    EACH                        8       SHARED VOTING POWER     
                 REPORTING                                                      
                   PERSON                               526,737
                    WITH                ----------------------------------------
                                                9       SOLE DISPOSITIVE POWER
                                                                              
                                                        148,327
                                        ----------------------------------------
                                               10       SHARED DISPOSITIVE POWER
                                                                              
                                                        526,737
- --------------------------------------------------------------------------------

      11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 675,064
- --------------------------------------------------------------------------------
      12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN 
                 SHARES*
                                                                             |_|
- --------------------------------------------------------------------------------
      13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                 4.6% (2.2% of the outstanding voting power)***
- --------------------------------------------------------------------------------
      14         TYPE OF REPORTING PERSON*
                 IN
- --------------------------------------------------------------------------------
*** The  outstanding  shares  of  Series D  Preferred  Stock of the  Issuer  are
entitled  to vote  together  with the  holders  of Common  Stock on all  matters
submitted  to a vote of  stockholders  of the Issuer.  As of March 9, 1999,  Mr.
Michael S. Weiss may be deemed  beneficially  to own (within the meaning of Rule
13d-3  under  the  Securities  Exchange  Act of 1934,  as  amended)  2.2% of the
aggregate  voting  power  of the  Common  Stock  and  Series D  Preferred  Stock
outstanding.


<PAGE>

                                  SCHEDULE 13D

                  This  Amendment  No. 13 amends and  supplements  the following
items of the Reporting  Persons'  Statement on Schedule 13D,  dated February 24,
1997, as amended to date (the "Schedule").

Item 3.  Source and Amount of Funds or Other Consideration

                  The information  contained in Item 3 to the Schedule is hereby
amended by adding the following:

                  Between  February 9, and March 9, 1999,  Aries Trust and Aries
Domestic  used their respective  general  funds to purchase  890,090 and 115,600
shares of Common Stock (additional "Purchased Common Stock"),  respectively,  on
the open market.

                  Aries Trust made the following purchases:

Date                       No. of Shares             Purchase Price
- ----                       -------------             --------------

2/2/99                     20,000                    $2.281
2/3/99                     20,000                    $2.250
2/4/99                     20,000                    $2.250
2/5/99                     20,000                    $2.172
2/8/99                     20,000                    $2.172
2/9/99                     20,000                    $2.016
2/10/99                    90,000                    $1.898
2/11/99                    20,000                    $1.969
2/12/99                   146,340                    $2.075
2/16/99                    20,000                    $2.234
2/18/99                    20,000                    $2.141
2/19/99                    20,000                    $2.125
2/22/99                    20,000                    $2.125
2/23/99                    20,000                    $1.984
2/24/99                    66,800                    $2.011
2/25/99                    66,800                    $1.967
2/25/99                   106,350                    $1.938
2/26/99                    66,800                    $2.229
3/1/99                     30,000                    $2.229
3/2/99                     21,000                    $2.198
3/3/99                     14,000                    $2.156
3/4/99                     14,000                    $2.109
3/5/99                     14,000                    $2.125
3/9/99                     14,000                    $2.109



                               Page 8 of 11 Pages
<PAGE>

                  Aries Domestic made the following purchase:

Date                       No. of Shares             Purchase Price
- ----                       -------------             --------------

2/12/99                    62,600                    $2.075
3/2/99                      9,000                    $2.198
3/3/99                      6,000                    $2.156
3/4/99                      6,000                    $2.109
3/5/99                      6,000                    $2.125
3/8/99                     20,000                    $2.047
3/9/99                      6,000                    $2.109


         In addition, on March 3, 1999, Aries Trust and Aries Domestic purchased
an  aggregate  of  20,000  shares  of  Series A  Preferred  Stock  in a  private
placement.  Aries Trust used  $126,962.50 of its general funds to acquire 14,000
shares of Series A Preferred  Stock,  which are convertible  into  approximately
101,572 shares of Common Stock and Aries Domestic used $54,412.50 of its general
funds to acquire 6,000 shares of Series A Preferred Stock, which are convertible
into approximately 43,531 shares of Common Stock.


Item 5.  Interest in Securities of Issuer.

         The  information  contained in Item 5 to the Schedule is hereby amended
and supplemented to read as follows:

                  (a) As  of  March  9,  1998:  Dr.   Rosenwald,   as  the  sole
                      shareholder  of  Paramount  Capital  and as the  holder of
                      Placement  Warrants and Advisory  Warrants,  may be deemed
                      beneficially  to own  23,311,443  shares  or  69.8% of the
                      Issuer's  Common  Stock;  Paramount  Capital,  through the
                      acquisitions  of  securities  by  Aries  Trust  and  Aries
                      Domestic,  may be deemed  beneficially  to own  20,445,050
                      shares  or 67.0% of the  Issuer's  Common  Stock;  and Mr.
                      Weiss,  as Managing Member of Hawkins and as the holder of
                      securities of the Issuer,  may be deemed  beneficially  to
                      own 675,064  shares or 4.6% of the Issuer's  Common Stock.
                      Aries  Domestic,  Aries  Trust and  Hawkins  may be deemed
                      beneficially  to own the  following  numbers  of shares of
                      Common Stock:

                      Aries Domestic   6,741,008
                      Aries Trust     13,704,042
                      Hawkins            526,737

                      Pursuant to Rule 13d-4  promulgated  under the  Securities
                      Exchange  Act of 1934,  as  amended,  the  Filing  Persons
                      disclaim  beneficial  ownership  of all the  Common  Stock
                      except the Purchased Common Stock.  Pursuant to Rule 13d-4
                      promulgated under the Securities  Exchange Act of 1934, as
                      amended,  the  Aries  Reporting  Persons,  Mr.  Weiss  and
                      Hawkins  each   disclaim   beneficial   ownership  of  the
                      securities held by each other.




                               Page 9 of 11 Pages



<PAGE>

                      The outstanding  shares of Series D Preferred Stock of the
                      Issuer are entitled to vote  together  with the holders of
                      Common  Stock  on  all  matters  submitted  to a  vote  of
                      stockholders  of the Issuer.  As of December 28, 1998, Dr.
                      Rosenwald, Paramount Capital and Aries Trust may be deemed
                      beneficially  to own  (within  the  meaning  of Rule 13d-3
                      under the  Securities  Exchange  Act of 1934,  as amended)
                      56.3%,  53.0% and 38.3%,  respectively,  of the  aggregate
                      voting  power of the Common  Stock and Series D  Preferred
                      Stock outstanding.

                  (b) Dr.  Rosenwald  and  Paramount  Capital share the power to
                      vote or to direct the vote and to dispose or to direct the
                      disposition  of  those  shares  owned  by  each  of  Aries
                      Domestic and Aries Trust. Dr. Rosenwald has the sole power
                      to vote or to direct  the vote and to dispose or to direct
                      the  disposition  of the shares  underlying  the Placement
                      Warrants and Advisory  Warrants held by him. Mr. Weiss and
                      Hawkins  share the power to vote or to direct the vote and
                      to  dispose  or to direct  the  disposition  of the shares
                      owned by Hawkins.  Mr. Weiss has the sole power to vote or
                      to  direct  the  vote  and to  dispose  or to  direct  the
                      disposition of the shares that he owns.


                  (c) Other than certain of the open market  purchases of Common
                      Stock  reported in Item 3, the Reporting  Persons have not
                      engaged in any  transactions  in the  Common  Stock of the
                      Issuer in the past 60 days.

                  (d)&(e)  Not applicable.








                               Page 10 of 11 Pages



<PAGE>

                                   SIGNATURES
                                   ----------

                  After reasonable  inquiry and to the best knowledge and belief
of the  undersigned,  the undersigned  certify that the information set forth in
this statement is true, complete and correct.

                                    PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   March 12, 1999
         New York, NY           By: /s/ Lindsay A. Rosenwald, M.D.
                                    ---------------------------------------
                                             Lindsay A. Rosenwald, M.D.
                                             Chairman

                                    ARIES DOMESTIC FUND, L.P.
                                    By: Paramount Capital Asset Management, Inc.
                                         General Partner

Dated:   March 12, 1999
         New York, NY           By: /s/ Lindsay A. Rosenwald, M.D.
                                    ---------------------------------------
                                             Lindsay A. Rosenwald, M.D.
                                             Chairman


                                    THE ARIES TRUST
                                    By: Paramount Capital Asset Management, Inc.
                                        Investment Manager

Dated:   March 12, 1999
         New York, NY           By: /s/ Lindsay A. Rosenwald, M.D.
                                    ---------------------------------------

                                             Lindsay A. Rosenwald, M.D.
                                             Chairman


Dated:   March 12, 1999
         New York, NY               /s/ Lindsay A. Rosenwald, M.D.
                                    ---------------------------------------
                                             Lindsay A. Rosenwald, M.D.


Dated:   March 12, 1999
         New York, NY               /s/ Mr. Michael S. Weiss
                                    ---------------------------------------
                                             Mr. Michael S. Weiss


                                    HAWKINS GROUP, LLC

Dated:   March 12, 1999
         New York, NY          By:  /s/ Mr. Michael S. Weiss
                                    ---------------------------------------

                                                Mr. Michael S. Weiss
                                                Managing member



                               Page 11 of 11 Pages



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