SCICLONE PHARMACEUTICALS INC
10-Q, 1996-05-15
PHARMACEUTICAL PREPARATIONS
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                                    FORM 10-Q




                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

(Mark One)

  X  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
- - -----             SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 1996

                                       OR

     TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
- - -----             SECURITIES EXCHANGE ACT OF 1934

For the transition period from ________________________to ______________________

Commission file number:  0-19825

                         SCICLONE PHARMACEUTICALS, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

       California                                     94-3116852
       ----------                                     ----------
(State or other jurisdiction                       (I.R.S. employer
of incorporation or organization)                 identification no.)


901 Mariners Island Blvd., Suite 315, San Mateo, California            94404
- - -----------------------------------------------------------            -----
         (Address of principal executive offices)                    (Zip code)

                                 (415) 358-3456
              (Registrant's telephone number, including area code)

                                 Not Applicable
                                 --------------
                    (Former name, former address and former
                   fiscal year, if changed since last report)

     Indicate by check mark whether the registrant (1) has filed all
reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days

         Yes    X          No
            --------         -------

         As of April 30, 1996, 17,436,561 shares of the registrant's Common
Stock, no par value, were issued and outstanding.


<PAGE>





                         SCICLONE PHARMACEUTICALS, INC.



                        INDEX

PART I.     FINANCIAL INFORMATION                                     PAGE NO.

Item 1.     Consolidated Financial Statements

            Consolidated Balance Sheets
                 March 31, 1996 and December 31, 1995                    3

            Consolidated Statements of Operations
                 Three months ended March 31, 1996 and 1995              4

            Consolidated Statements of Cash Flows                       
                 Three months ended March 31, 1996 and 1995              5

            Notes to Consolidated Financial Statements                   6

Item 2.     Management's Discussion and Analysis of Financial
                 Condition and Results of Operations                     7

PART II.    OTHER INFORMATION

Item 6.     Exhibits and Reports on Form 8-K                             10


Signatures                                                               11



                                       2
<PAGE>

PART I.  FINANCIAL INFORMATION

Item  1. Consolidated Financial Statements

<TABLE>

                         SCICLONE PHARMACEUTICALS, INC.

                           CONSOLIDATED BALANCE SHEETS

<CAPTION>
                                                ASSETS

                                                                                             March 31,                December 31,
                                                                                               1996                       1995
                                                                                           ==============             =============
                                                                                            (unaudited)
<S>                                                                                         <C>                       <C>          
Current assets:
    Cash and cash equivalents                                                               $   3,892,265             $   3,986,307
    Short-term investments                                                                     12,344,208                15,467,685
    Accounts receivable                                                                           120,833                   108,410
    Inventory                                                                                   2,532,746                 2,360,479
    Prepaid expenses and other current assets                                                   2,268,999                 1,955,930
                                                                                            -------------             -------------
Total current assets                                                                           21,159,051                23,878,811

Property and equipment, net                                                                       318,348                   313,703
Long-term investments                                                                          28,951,453                27,935,835
Notes receivable from officers                                                                  1,761,955                 1,964,065
Other assets                                                                                       58,386                    58,381
                                                                                            -------------             -------------
Total assets                                                                                $  52,249,193             $  54,150,795
                                                                                            =============             =============

                                  LIABILITIES AND SHAREHOLDERS' EQUITY

Current liabilities:
    Accounts payable                                                                        $     394,302             $     472,477
    Accrued compensation and benefits                                                             874,072                 1,086,904
    Accrued clinical trial expense                                                              1,668,696                 2,054,741
    Accrued professional fees                                                                   1,121,500                   765,000
    Other accrued expenses                                                                        320,184                   216,411
                                                                                            -------------             -------------
Total current liabilities                                                                       4,378,754                 4,595,533

Shareholders' equity:
    Preferred stock, no par value; 10,000,000 shares
        authorized ; no shares issued and outstanding                                                --                        --
     Common stock, no par value; 75,000,000 shares
        authorized; 17,386,590 and 16,807,257 shares
        issued and outstanding                                                                108,267,851               105,915,548
     Net unrealized gain on available-for-sale securities                                          76,612                   450,086
     Accumulated deficit                                                                      (60,344,021)              (56,605,519)
     Deferred compensation                                                                       (130,003)                 (204,853)
                                                                                            -------------             -------------
Total shareholders' equity                                                                     47,870,439                49,555,262
                                                                                            -------------             -------------
Total liabilities and shareholders' equity                                                  $  52,249,193             $  54,150,795
                                                                                            =============             =============

<FN>

                              See notes to consolidated financial statements

</FN>
</TABLE>


                                       3
<PAGE>

                         SCICLONE PHARMACEUTICALS, INC.

                      CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (unaudited)


                                                     Three months ended
                                                          March 31,
                                                   1996                 1995
                                              =============       =============

Product sales                                 $    126,308         $         --

Cost of product sales                              199,800                   --
                                              ------------         ------------

Gross profit                                       (73,492)                  --

Operating expenses:
     Research and development                    2,534,601            2,319,184
     Marketing                                   1,070,817            1,146,389
     General and administrative                    775,698              789,964
                                              ------------         ------------
Total operating expenses                         4,381,116            4,255,537
                                              ------------         ------------

Loss from operations                            (4,454,608)          (4,255,537)

Interest and investment income, net                716,106              686,147
                                              ------------         ------------

Net loss                                      $ (3,738,502)        $ (3,569,390)
                                              ============         ============

Net loss per share                            $      (0.22)        $      (0.21)
                                              ============         ============

Weighted average shares used in
     computing per share amounts                17,051,546           17,086,780
                                              ============         ============


                 See notes to consolidated financial statements


                                       4
<PAGE>

<TABLE>

                         SCICLONE PHARMACEUTICALS, INC.

                      CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (unaudited)

<CAPTION>

                                                                                                       Three months ended
                                                                                                            March 31,
                                                                                                 1996                       1995
                                                                                            =============              ============
<S>                                                                                         <C>                        <C>          
Operating activities:
   Net loss                                                                                 $ (3,738,502)              $ (3,569,390)
   Adjustments to reconcile net loss to net
   cash used in operating activities:
      Depreciation and amortization                                                              116,111                    127,818
      Changes in operating assets and liabilities:
         Prepaid expenses and other assets                                                      (110,964)                  (593,189)
         Accounts receivable                                                                     (12,423)                      --
         Inventory                                                                              (172,267)                      --
         Accounts payable and other accrued expenses                                              25,598                    (45,952)
         Accrued clinical trial expense                                                         (386,045)                    19,051
         Accrued professional fees                                                               356,500                    305,750
         Accrued compensation and benefits                                                      (212,832)                  (660,821)
                                                                                            ------------               ------------
Net cash used in operating activities                                                         (4,134,824)                (4,416,733)
                                                                                            ------------               ------------

Investing activities:
   Purchase of property and equipment                                                            (45,906)                   (41,107)
   Sale of marketable securities, net                                                          1,734,385                  6,231,072
                                                                                            ------------               ------------
Net cash provided by investing activities                                                      1,688,479                  6,189,965
                                                                                            ------------               ------------

Financing activities:
   Proceeds from issuance of common stock, net                                                 2,352,303                       --
                                                                                            ------------               ------------
Net cash provided by financing activities                                                      2,352,303                       --
                                                                                            ------------               ------------
Net (decrease) increase in cash and cash equivalents                                             (94,042)                 1,773,232
Cash and cash equivalents, beginning of period                                                 3,986,307                  8,292,888
                                                                                            ------------               ------------
Cash and cash equivalents, end of period                                                    $  3,892,265               $ 10,066,120
                                                                                            ============               ============
Supplemental disclosures of noncash financing activities:
   Net unrealized (loss) gain on available-for-sale securities                              $   (373,474)              $    804,096

<FN>
                                                                 
                 See notes to consolidated financial statements
</FN>
</TABLE>


                                       5
<PAGE>

                         SCICLONE PHARMACEUTICALS, INC.

                   Notes to Consolidated Financial Statements


1.       The accompanying unaudited consolidated financial statements have been
         prepared in conformity with generally accepted accounting principles
         consistent with those applied in, and should be read in conjunction
         with, the audited financial statements for the year ended December 31,
         1995. The interim financial information reflects all normal recurring
         adjustments which are, in the opinion of management, necessary for a
         fair presentation of the results for the interim period presented. The
         interim results are not necessarily indicative of results for the full
         year.

2.       Net loss per share has been computed using the weighted average number
         of common shares outstanding during each period presented. Common
         equivalent shares for outstanding options and warrants were not
         included in the weighted average shares outstanding because the effect
         would be antidilutive.

<TABLE>

3.       The following is a summary of available-for-sale securities at March
         31, 1996:

                                                             Available-for-Sale Securities
                                              --------------------------------------------------------------
                                                                Gross            Gross           Estimated
                                               Amortized     Unrealized        Unrealized           Fair
                                                 Cost           Gains            Losses             Value
                                                 ----           -----            ------             -----
         <S>                                  <C>                <C>           <C>               <C>        
         U.S. government &
            agency obligations                $26,619,426        $ 20,771      $(231,886)        $26,408,311
         Corporate obligations                 14,059,333          28,777        (99,908)         13,988,202
         Corporate equity securities              540,290         358,858             --             899,148
                                              -----------        --------      ---------         -----------
                                              $41,219,049        $408,406      $(331,794)        $41,295,661
                                              ===========        ========       =========        ===========

</TABLE>

         The amortized cost and estimated fair value of debt and marketable
         securities at March 31, 1996 by contractual maturity are shown below.


                                                                    Estimated
                                                  Amortized            Fair
                                                     Cost             Value
                                                     ----             -----
         Due in one year or less                  $11,513,451      $11,445,060
         Due after one year through three years    12,280,755       12,205,216
         Due after three years                     16,884,553       16,746,237
                                                   ----------       ----------
                                                   40,678,759       40,396,513
         Corporate equity securities                  540,290          899,148
                                                   ----------       ----------
                                                  $41,219,049      $41,295,661
                                                  ===========      ===========

4.       The following is a summary of inventories at March 31, 1996:

         Raw materials                          $2,478,113
         Finished goods                             54,633
                                                ----------
                                                $2,532,746
                                                ==========


                                       6
<PAGE>


Item 2.  Management's Discussion and Analysis of Financial Condition 
         and Results  of Operations


         Except for historical information contained herein, the following
material is a forward-looking statement that is subject to certain risks and
uncertainties. These risks and uncertainties include the Company's reliance on a
single product, ZADAXIN(R) thymosin alpha 1, for its revenues, the absence of
regulatory approval for ZADAXIN in significant markets, uncertainties regarding
ZADAXIN's efficacy and outcome of ongoing clinical trials, risks associated with
the manufacture and supply of ZADAXIN and relationships with collaborative
partners, and competition from competing therapies, as well as other risks and
uncertainties described herein and in the Company's Annual Report on Form 10-K
and its other reports filed with the Securities Exchange Commission.

         The Company is an international biopharmaceutical company involved in
the acquisition, development and commercialization of pharmaceuticals worldwide.
The Company's focus is on therapeutics for diseases that are chronic and
life-threatening, including hepatitis B and C, cancer and immune system
disorders. To date, the Company's principal focus has been the development and
commercialization of ZADAXIN.

         From commencement of operations through March 31, 1996, the Company
incurred a cumulative net loss of approximately $60.3 million. The Company
expects its operating expenses to increase over the next several years as it
expands its research and development, clinical testing and marketing
capabilities. The Company's ability to achieve a profitable level of operations
currently is dependent in large part on obtaining additional favorable clinical
data on ZADAXIN (particularly from the Phase III trial in Taiwan), securing
regulatory approvals in additional countries, acquiring rights to additional
drugs, entering into and extending  agreements for product development and
commercialization, where appropriate, and expanding from development to
marketing. There can be no assurance that the Company will ever achieve a
profitable level of operations.

         The Company's operating results may fluctuate from period to period as
a result of, among other things, the timing and costs associated with clinical
trials and the regulatory approval process, and the acquisition of additional
product rights. The Company participates in a highly dynamic industry, which
often results in significant volatility of the Company's common stock price. Any
setbacks in clinical trials, in the regulatory approval process or in
relationships with collaborative partners, and any shortfalls in revenue or
earnings from levels expected by securities analysts, among other developments,
could have an immediate and significant adverse effect on the trading price of
the Company's common stock in any given period.

Results of Operations

         Product sales reached approximately $126,000 for the three month period
ended March 31, 1996. There were no product sales for the corresponding period
in 1995. The Company commenced shipment of ZADAXIN in the second quarter of 1995
and has been recording product sales under a named patient registration program.
The Company has filed for approval to market ZADAXIN in several countries and
anticipates additional filings in other countries. As a result, the Company
expects product sales to increase during 1996 and beyond if additional ZADAXIN
marketing approvals are obtained. Although the Company remains optimistic
regarding the prospects of ZADAXIN, there can be no assurance that the Company
will ever achieve significant levels of product sales.


                                       7
<PAGE>

         Cost of product sales was approximately $200,000 for the three month
period ended March 31, 1996. There was no cost of product sales for the
corresponding period in 1995. Cost of product sales relates to the Company's
commencement of ZADAXIN sales in the second quarter of 1995 and the fixed costs
associated with acquiring and warehousing product inventory. The Company expects
cost of product sales to vary from quarter to quarter, depending upon the level
of product sales and the absorption of fixed product-related costs.

         Research and development expenses increased to approximately $2,535,000
for the three month period ended March 31, 1996 from approximately $2,319,000
for the corresponding period in 1995. This increase is primarily attributable to
increased payroll costs. The Company is currently reviewing its U.S. and
European ZADAXIN clinical trial strategy and the results of this review will
have a significant effect on the Company's research and development expenses.
In general,  the Company expects this research and development expenses to
increase over the next several years and to vary quarter to quarter as the
Company initiates additional clinical trials and testing acquires product
rights, initiates additional trials, and expands regulatory activities.

         Marketing expenses were approximately $1,071,000 for the three month
period ended March 31, 1996 as compared to $1,146,000 for the corresponding
period in the prior year. This decrease is primarily attributable to decreased
payroll costs related to an executive officer who left the Company in 1995
offset by increased professional services and travel expenses. The Company
expects marketing expenses to increase significantly in the next several years
as it expands its commercialization and marketing efforts and pursues other
strategic relationships.

         General and administrative expenses were approximately $776,000 for the
three month period ended March 31, 1996 as compared to approximately $790,000
for the corresponding period in the prior year. This decrease is primarily
attributable to decreased expenses for professional services, primarily legal
services associated with a 1994 securities class action lawsuit. In the near
term, the Company expects general and administrative expenses to increase as the
Company augments its general and administrative activities to support increased
expenditures on clinical trials and testing, and regulatory,
pre-commercialization and marketing activities.

         Net interest and investment income was approximately $716,000 for the
three month period ended March 31, 1996 as compared to approximately $686,000 in
the same period in 1994. This increase primarily resulted from overall increased
interest rates and gains from the sale of certain short-term investments.




                                       8
<PAGE>


Liquidity and Capital Resources

         At March 31, 1996, the Company had approximately $45,188,000 in cash,
cash equivalents and highly liquid short and long-term investments.

         Net cash used by the Company in operating activities amounted to
approximately $4,135,000 for the three month period ended March 31, 1996. Net
cash used in operating activities in the 1996 period is greater than the
Company's net loss for such period primarily due to cash used for inventory
purchases, the prepayment of certain future period expenses and decreases in
amounts owed to third parties for goods and services related to clinical trial
expenses and compensation and benefits. These uses were offset by increases in
amounts owed for accrued professional fees and noncash charges associated with
depreciation and amortization. Net cash used in operations amounted to
approximately $4,417,000 for the three month period ended March 31, 1995. Net
cash used in operating activities in the 1995 period is greater than the
Company's net loss for such period primarily due to cash used for the prepayment
of certain future period expenses and decreases in amounts owed to employees for
compensation and benefits. These uses of cash were offset by increases in
amounts owed for accrued professional fees and noncash charges associated with
depreciation and amortization.

         Net cash provided by investing activities for the three month period
ended March 31, 1996 related to the net sale of approximately $1,735,000 of
marketable securities offset by the purchase of $46,000 in equipment and
furniture. Net cash provided by investing activities for the comparable 1995
period primarily resulted from the net sale of $6,231,000 of marketable
securities offset by the purchase of $41,000 of equipment and furniture.

         Net cash provided by financing activities for the three month period
ending March 31, 1996 primarily consisted of approximately $2,352,000 in
proceeds received fro the issuance of common stock under the Company's stock
option plan. There were no financing activities for the three month period
ending March 31, 1995.

         Management believes its existing capital resources and interest on
funds available are adequate to maintain its current and planned operations for
at least through 1997. However, the Company's capital requirements may change
depending upon numerous factors, including the availability of complementary
products, technologies and businesses, the results of clinical trials and
testing, the timing of regulatory approvals, developments in relationships with
collaborative partners and the status of competitive products. If the Company
cannot eventually generate sufficient funds from operations, it will need to
raise additional financing. There can be no assurance that such financing will
be available on acceptable terms, or at all.

                                       9
<PAGE>

PART II.  OTHER INFORMATION

Item 6.   Exhibits and Reports on Form 8-K

(a)       Exhibits

          Exhibit
           Number                        Description
           ------                        -----------

          10.1    Compensation agreement dated January  19, 1996, between the
                  Registrant and Philip H. Vander Werf*

          10.2    Employment agreement, dated February 1, 1996, between the
                  Registrant and Donald R. Sellers*

          10.3    Sublease, dated January 1, 1996, between the Registrant
                  and Cord Blood Registry, Inc., concerning property located at
                  901 Mariners Island Boulevard, San Mateo, California

          27      Financial Data Schedule

(b)       Reports on Form 8-K

          None


*         Management Compensatory plan or arrangement


                                       10
<PAGE>


                                   SIGNATURES


         Pursuant to the requirements of the Securities and Exchange Act of
1934, the Registrant has duly caused this report to be signed on its behalf by
the undersigned thereunto duly authorized.


                                           SCICLONE PHARMACEUTICALS, INC.
                                                     (Registrant)



Date:   May 14, 1996                          Donald R. Sellers 
                                       -------------------------------
                                              Donald R. Sellers
                                           Chief Executive Officer
                                        (Principal Executive Officer)


Date:   May 14, 1996                            Mark A. Culhane
                                       -------------------------------
                                                Mark A. Culhane
                                      Vice President, Finance and Administration
                                          and Chief Financial Officer
                                      (Principal Financial & Accounting Officer)





                                       11

<PAGE>

                                 EXHIBIT INDEX

Exhibit
Number                            Description
- - -------                           -----------

  10.1       Compensation Agreement dated January 19, 1996 between the
             Registrant and Philip H. Vander Werf*

  10.2       Employment Agreement dated February 1, 1996 between the
             Registrant and Donald R. Sellers

  10.3       Sublease dated January 1, 1996, between the Registrant and Cord
             Blood Registry, Inc., concerning property located at 901
             Mariner's Island Boulevard, San Mateo, California

  27         Financial Data Schedule**

- - -----------------

*        Management Compensatory plan or arrangement.

**       This exhibit shall not be deemed  filed  for  purposes of Section 11 of
         the Securities Act, Section 18 of the Exchange Act, and  Section 323 of
         the Trust Indenture Act, or otherwise be subject to the  liabilities of
         such sections.






                             COMPENSATION AGREEMENT


SciClone Pharmaceuticals ("SciClone") and Philip H. Vander Werf ("Vander Werf")
hereby agree as follows:

1.       SciClone will make payments in the amount of Thirty Two Thousand Five
         Hundred Dollars ($32,500) per month, less applicable withholding as
         required by law, for the period beginning January 1, 1996 and ending
         December 31, 1996. Such payments will be made by direct deposit on or
         before the fifteenth day and the last day of each month.

2.       On January 19, 1996, SciClone will make a one time payment in the
         amount of Twenty Thousand Seven Hundred Dollars ($20,700) as full and
         complete payment of accrued and unused personal time off, including,
         but not limited, to vacation and sick leave.

3.       SciClone will forgive outstanding loans previously made to Vander Werf
         totalling Three Hundred Eighty Thousand Dollars ($380,000). In
         addition, SciClone will make payments in the amount of Twenty Nine
         Thousand Dollars ($29,000) per month, less applicable withholding as
         required by law, for the period beginning January 1, 1996 and ending
         December 31, 1996 as full and complete payment of the income and
         payroll tax effects related to the forgiveness of the loans. Such
         payments will be made by direct deposit on or before the fifteenth day
         and the last day of each month. Vander Werf shall in no event be
         entitled to additional amounts hereunder regardless of the actual
         income and payroll taxes incurred by him.

4.       As of January 19, 1996, Vander Werf shall have the option, under the
         Consolidated Omnibus Budget Reconciliation Act of 1985 (COBRA), to
         continue medical and dental coverage at the same level of coverage as
         of January 19, 1996. SciClone shall pay for Vander Werf's purchase of
         the medical and dental coverage available to him upon his election to
         receive such continued health benefits under COBRA until December 31,
         1996 or until Vander Werf becomes employed by another employer that
         offers medical and dental coverage, whichever is first. Vander Werf is
         obligated to inform SciClone within five days of becoming eligible for
         such coverage by another employer.

5.       As of January 19, 1996, Vander Werf's options exercisable for Two
         Hundred Fifty Seven Thousand Three Hundred Thirty Four (257,334) shares
         of SciClone Common Stock shall be fully vested. The exercise period for
         such stock options shall terminate on January 18, 1997. At any time on
         or before January 18, 1997, Vander Werf may exercise his options at the
         following prices: One Hundred Ninety Four Thousand Three Hundred Thirty
         Four shares (194,334) at an exercise price of Three Dollars ($3.00) per
         share; Twenty Four Thousand shares (24,000) at an exercise price of
         Five Dollars and Fifty Cents ($5.50) per share; and Thirty Nine
         Thousand shares (39,000) at an exercise price of Twelve Dollars Fifty
         Cents ($12.50) per share. Vander Werf understands and acknowledges that
         the timing of his option exercise may effect the tax treatment of such
         exercise.


SCICLONE PHARMACEUTICALS



By:
     ---------------------------           -------------------------------------
         Thomas E. Moore                         Philip H. Vander Werf
         Chairman & CEO

Dated:                                     Dated:


                              EMPLOYMENT AGREEMENT


         This Employment Agreement (the "Agreement") is entered into February 1,
1996  between  SciClone  Pharmaceuticals,  Inc. a California  corporation,  (the
"Company"), and Donald R. Sellers, an individual ("Employee").

         In consideration of the promises and the terms and conditions set forth
in this Agreement, the parties agree as follows:

1.  Position.  During  the  term of this  Agreement,  the  Company  will  employ
Employee,  and Employee  will serve the Company as its  President  and will have
such other  responsibilities,  authority  and titles as may from time to time be
assigned to Employee by the Board of Directors of the Company.

2.  Duties.  Employee  will  have  the  duties  and  responsibilities  generally
associated  with the positions held by Employee and as the Board of Directors of
the Company may from time to time  determine.  Employee  will comply with and be
bound by Company's  operating policies,  procedures,  and practices from time to
time in effect during  Employee's  employment.  Employee  hereby  represents and
warrants that he is free to enter into and fully perform this  Agreement and the
agreements  referred to herein  without  breach of any  agreement or contract to
which he is a party or by which he is bound.

3.       Compensation and Benefits.

         3.1 Base  Salary.  The Company  agrees to pay Employee a base salary of
$400,000.  The base  salary  shall be  payable  as  earned  in  accordance  with
Company's  customary payroll practice.  If this Agreement is renewed pursuant to
Section 4,  Employee's  base salary for future years shall be  negotiated by the
Company and Employee.

         3.2 Cash Bonus.  The Company agrees to pay Employee a bonus of $200,000
upon the full  achievement  of  specified  goals agreed upon by Employee and the
Company.  The bonus shall be payable in accordance with the Company's  customary
bonus payment practices unless otherwise agreed by the Company and Employee.  If
this Agreement is renewed pursuant to Section 5, Employee's future bonus targets
and goals shall be negotiated by the Company and Employee.

         3.3 Cost-of-Living Assistance Payments. The Company (or a subsidiary of
the Company) agrees to continue the cost-of-living  assistance payments Employee
received as Managing  Director,  Pacific Rim  Operations of the Company at their
current level through July 31, 1996.

         3.4 Car  Allowance.  Employee  will receive a car allowance of $850 per
month.

         3.5  Additional  Benefits.  Employee will be eligible to participate in
the Company's employee benefit plans of general  application,  including without
limitation  those plans covering  pension and profit sharing,  stock  purchases,
stock options,  and those plans covering life,  health,



<PAGE>

and dental  insurance in accordance  with the rules  established  for individual
participation  in any such plan and applicable  law.  Employee will receive such
other  benefits,  including  vacation,  holidays and sick leave,  as the Company
generally provides to its employees holding similar executive  positions as that
of Employee.

         3.6 Expenses.  The Company will  reimburse  Employee for all reasonable
and necessary  expenses  incurred by Employee in  connection  with the Company's
business,  provided  that such  expenses are in  accordance  with the  Company's
applicable  policy and are properly  documented  and accounted for in accordance
with the requirements of the Internal Revenue Service.

4.       Term and Termination.

         4.1 Term.  This Agreement shall terminate 12 months from the date first
entered into above (the  "Anniversary  Date") unless  renewed by the Company and
Employee.

         4.2  Events of  Termination.  The  Agreement  may  terminated  upon the
occurrence of any one of the following events:

                  (a) The Company's  determination made in good faith that it is
terminating Employee for "cause" (as defined herein) ("Termination for Cause").

                  (b)  The  Company's   determination  that  it  is  terminating
Employee without "cause" (as defined herein), which determination may be made by
the Company at any time at the Company's sole discretion,  for any reason or for
no reason ("Termination Without Cause").

                  (c) The effective date of a written notice sent to the Company
from Employee stating that Employee is electing to terminate his employment with
the Company ("Voluntary Termination").

         4.3  "Cause"  Defined.  For  purposes  of this  Agreement,  "cause" for
Employee's termination will exist at any time after the happening of one or more
of the following events:

                  (a)  Employee's  willful  misconduct  or gross  negligence  in
performance of his duties hereunder,  inducing  Employee's  refusal to comply in
any  material  respect  with the  legal  directives  of the  Company's  Board of
Directors so long as such  directives are not  inconsistent  with the Employee's
position and duties,  and such refusal to comply is not remedied within ten (10)
working days after written notice from Company, which written notice shall state
that failure to remedy such conduct may result in Termination for Cause.

                  (b) Dishonest or fraudulent  conduct,  a deliberate attempt to
do an injury to the Company,  or conduct that materially  discredits the Company
or is materially detrimental to the reputation of the Company.

                  (c) Employee's incurable material breach of any element of the
Company's Proprietary  Information and Inventions  Agreement,  including without
limitation,   Employee's  theft  or  other  misappropriation  of  the  Company's
proprietary information.

                                      -2-
<PAGE>

         4.4 "Disability" Defined. For purposes or this Agreement,  "disability"
will mean that the Board of Directors has determined, based on competent medical
evidence,  that the Employee has become  incapable,  mentally or physically,  of
substantially performing his services and discharging his duties hereunder for a
period in excess of six (6) months.

5.       Effect of Termination.

         5.1 Termination for Cause or Voluntary Termination. In the event of any
termination of this Agreement pursuant to Sections 4.2(a) or 4.2(c), the Company
shall pay Employee the compensation and benefits  otherwise  payable to Employee
under  Section 3 through the date of  termination.  Employee's  rights under the
Company's  benefit plans of general  application  shall be determined  under the
provisions of those plans.

         5.2 Termination  Without Cause. In the event of any termination of this
Agreement pursuant to Section 4.2(b), or as a result of a material diminution of
Employee's  duties  and  responsibilities  by the  Company,  or as a  result  of
Employee's death or disability (as defined herein),

                  (a) the  Company  shall  pay  Employee  the  compensation  and
benefits  otherwise  payable to  Employee  under  Section 3 through  the date of
termination,  except that  health-related  benefits  shall continue for one year
beyond the effective date of termination.

                  (b) within seven (7) days of  termination,  Company  shall pay
Employee  a  severance  payment  equal to the sum of one  year of the  Employees
then-current base salary, car allowance and the bonus Employee could have earned
had he  continued  employment  with the Company  through the end of the calendar
year in which termination occurs,

                  (c) the Company shall cause all of the Employee's  outstanding
stock  options  to become  immediately  vested and the  exercise  period of such
options will be extended for a period of one year, provided,  however, that such
extension shall not exceed the original term of such options, and

                  (d)  Employee's  rights under the  Company's  benefit plans of
general application shall be determined under the provisions of those plans.

6.       Miscellaneous.

         6.1 Severability.  If any provision of this Agreement shall be found by
any   arbitrator   or  court  of  competent   jurisdiction   to  be  invalid  or
unenforceable,  then the parties  hereby waive such provision to the extent that
it is found to be invalid or unenforceable and to the extent that to do so would
not deprive one of the parties of the substantial  benefit of its bargain.  Such
provision shall, to the extent allowable by law and the preceding  sentence,  be
modified by such arbitrator or court so that it becomes  enforceable  consistent
with the intent of this  Agreement  and, as  modified,  shall be enforced as any
other provision  hereof,  all the other provisions  continuing in full force and
effect.

                                      -3-
<PAGE>

         6.2 No  Waiver.  The  failure  by either  party at any time to  require
performance  or compliance by the other of any of its  obligations or agreements
shall in no way affect the right to require such  performance  or  compliance at
any time  thereafter.  The waiver by either  party of a breach of any  provision
hereof shall not be taken or held to be a waiver of any  preceding or succeeding
breach of such  provision or as a waiver of the provision  itself.  No waiver of
any kind shall be effective or binding, unless it is in writing and is signed by
the party against whom such waiver is sought to be enforced.

         6.3 Assignment. This Agreement and all rights hereunder are personal to
Employee  and may not be  transferred  or assigned by Employee at any time.  The
Company may assign its rights,  together with its obligations hereunder,  to any
parent,  subsidiary,  affiliate or successor,  or in  connection  with any sale,
transfer or other  disposition of all or  substantially  all of its business and
assets,  provided,  however,  that  any  such  assignee  assumes  the  Company's
obligations hereunder.

         6.4  Withholding.  All sums  payable  to  Employee  hereunder  shall be
reduced by all federal, state, local and other withholding and similar taxes and
payments required by applicable law.

         6.5  Amendment.  This Agreement may be amended,  modified,  superseded,
canceled,  renewed or extended only by an agreement in writing  executed by both
parties hereto.

         6.6 Notices. All notices and other communications required or permitted
under this Agreement shall be in writing and hand delivered, sent by telecopier,
sent by certified  first class mail,  postage  pre-paid,  or sent by  nationally
recognized express courier service.  Such notices and other communications shall
be effective upon receipt if hand delivered or sent by telecopier, five (5) days
after mailing if sent by mail, and one (1) day after dispatch if sent by express
courier, to the following addresses, or such other addresses as any party, shall
notify the other parties:

        If to the Company:        SciClone Pharmaceuticals, Inc.
                                  901 Mariners Island Blvd.
                                  San Mateo, CA 94404
                                  Attention:  Chairman of the Board of Directors
                                  Telecopier: (415) 358-3469

        If to Employee:           Donald R. Sellers
                                  c/o SciClone Pharmaceuticals, Inc.
                                  901 Mariners Island Boulevard
                                  San Mateo, CA 94404
                                  Telecopier: (415) 358-3469

         6.7 Binding Nature.  This Agreement shall be binding upon, and inure to
the benefit of, the  successors and personal  representatives  of the respective
parties hereto.

         6.8  Headings.  The  headings  contained  in  this  Agreement  are  for
reference purposes only and shall in no way affect the meaning or interpretation
of this Agreement.  In this 

                                      -4-
<PAGE>


Agreement,  the singular includes the plural,  the plural included the singular,
the masculine gender includes both male and female referents,  and the word "or"
is used in the inclusive sense.

         6.9  Counterparts.  This  Agreement  may be  executed  in  two or  more
counterparts,  each of which shall be deemed to be an original but all of which,
taken together, constitute one and the same agreement.

         6.10 Governing  Law. This  Agreement and the rights and  obligations of
the parties  hereto shall be construed in accordance  with the laws of the State
of California, without giving effect to the principles of conflict of laws.


         IN WITNESS  WHEREOF,  the  Company  and  Employee  have  executed  this
Agreement as of the date first above written.

SCICLONE PHARMACEUTICALS, INC.              EMPLOYEE


By: ____________________________            ______________________________
                                            Donald R. Sellers

Name:___________________________


Title:__________________________



                                      -5-



                               SUBLEASE AGREEMENT


         This sublease agreement ("Agreement") for 901 Mariner's Island Blvd.,
Suite 275, San Mateo, CA 94404 (the "Office Space"), dated and effective as of
January 1, 1996, is by and between SciClone Pharmaceuticals, Inc. ("SCLN") and
Cord Blood Registry, Inc. ("CBR").

         WHEREAS, SCLN wishes to sublease the Office Space to CBR; and

         WHEREAS, CBR wishes to sublease the Office Space from SCLN.

         NOW, THEREFORE, BE IT RESOLVED, that CBR and SCLN agree as follows:

         1. Rent. CBR shall pay directly to SCLN on a month-to-month basis, rent
for the Office Space at the rate stated in the attached Appendix A.

         2. Termination.  Upon 120 days written notice to the other,  either CBR
or SCLN may terminate this Agreement.

                   In the event SCLN terminates this Agreement, CBR shall vacate
the Office Space within 120 days from its receipt of SCLN's termination notice.

                   If this Agreement is not otherwise terminated then it shall
terminate on April 30, 1998.

         3.  Improvements.  CBR will have the right to improve the Office Space,
upon its receipt of SCLN's and Spieker  Properties'  ("Spieker")  prior  written
approval,  including  opening wall space and the  installation  of telephone and
data equipment lines and jacks, as necessary and appropriate.  Such improvements
and/or  modifications  to the Office Space,  shall become  SCLN's  property upon
termination of this Agreement.

         4. Use. CBR will maintain the Office Space as per SCLN's agreement with
Spieker, as stated in the original lease agreement, dated September 10, 1991
("Original Lease"), as amended.

         5.  Expenses.  CBR  will  pay,  on a  pass-through  basis,  incremental
operating expenses charged to SCLN by Spieker,  as stated in Appendix A attached
hereto.


<PAGE>



         6. Notices. Any notice or other communication required or permitted to
be given to either party hereto shall be in writing and shall be deemed to have
been properly given and to be effective on the date of delivery if delivered in
person or by facsimile or five (5) days after mailing by registered or certified
mail, postage paid, to the other party at the following address:

                   In the case of SciClone Pharmaceuticals:

                           SciClone Pharmaceuticals, Inc.
                           901 Mariners Island Boulevard, #315
                           San Mateo, California 94404
                           Telephone:  415/358-3456
                           FAX:  415/358-3469
                           Attention:  Mark A. Culhane, CFO

                   In the case of Cord Blood Registry:

                           Cord Blood Registry, Inc.
                           901 Mariners Island Boulevard, #275
                           San Mateo, California 94404
                           Telephone:  415/______________________
                           FAX:  415/_________________________
                           Attention:  President



         To the  extent  not  otherwise  modified  herein,  all other  terms and
conditions of the Original Lease, as amended, shall apply to this Agreement,  as
agreed to this 3rd day of January, 1996.

<PAGE>



         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the date set forth in the first paragraph hereof.


SCICLONE PHARMACEUTICALS, INC.           CORD BLOOD REGISTRY, INC.



______________________________________   _______________________________________
Signature                                Signature


______________________________________   _______________________________________
Printed Name                             Printed Name


______________________________________   _______________________________________
Title                                    Title


______________________________________   _______________________________________
Date                                     Date




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<NAME>                        SCICLONE PHARMACEUTICALS, INC.
       
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