SCICLONE PHARMACEUTICALS INC
S-2/A, 1998-09-14
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
   AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 14, 1998
                                               REGISTRATION NO. 333-60425
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                AMENDMENT NO. 2
                                      to
                                    FORM S-2
             REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933


                         SCICLONE PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)


          CALIFORNIA                                            94-3116852
(State or other jurisdiction of                                (IRS Employer
incorporation or organization)                               Identification No.)

                    901 MARINERS ISLAND BOULEVARD, SUITE 205
                           SAN MATEO, CALIFORNIA 94404
                                 (650) 358-3456
                   (Address, including zip code, and telephone
                         number, including area code, of
                    registrant's principal executive offices)


                                DONALD R. SELLERS
                      PRESIDENT AND CHIEF EXECUTIVE OFFICER
                         SCICLONE PHARMACEUTICALS, INC.
                    901 MARINERS ISLAND BOULEVARD, SUITE 205
                           SAN MATEO, CALIFORNIA 94404
                                 (650) 358-3456
            (Name, address, including zip code, and telephone number,
                   including area code, of agent for service)

                                   Copies to:
                             J. HOWARD CLOWES, ESQ.
                        Gray Cary Ware & Freidenrich LLP
                         139 Townsend Street, Suite 400
                         San Francisco, California 94107
                                 (415) 836-2500

- --------------------------------------------------------------------------------

         APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: From
time to time as described in the Prospectus after the effective date of this
Registration Statement.

         If any of the securities being registered on this Form are to be
offered on a delayed or continuous basis pursuant to Rule 415 under the
Securities Act of 1933, check the following box. [X]

         If the registrant elects to deliver its latest annual report to
security holders, or a complete and legal facsimile thereof, pursuant to Item
11(a)(1) of this Form, check the following box. [X]

         If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, check the following box and
list the Securities Act registration statement number of the earlier effective
registration statement for the same offering. [ ] _______________

         If this Form is a post-effective amendment filed pursuant to Rule
462(b) under the Securities Act, check the following box and list the Securities
Act registration statement number of the earlier effective registration
statement for the same offering. [ ] _______________

         If this Form is a post-effective amendment filed pursuant to Rule
462(c) under the Securities Act, check the following box and list the Securities
Act registration statement number of the earlier effective registration
statement for the same offering. [ ] _______________

         If delivery of the prospectus is expected to be made pursuant to Rule
434, please check the following box. [ ]


THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR DATES
AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL FILE
A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION STATEMENT
SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(a) OF THE
SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME
EFFECTIVE ON SUCH DATE AS THE COMMISSION, ACTING PURSUANT TO SUCH SECTION 8(a),
MAY DETERMINE.

<PAGE>   2


EXPLANATORY NOTE

         Amendment No. 2 is being filed for the purpose of filing Exhibit 23.1
to the Registration Statement.  
<PAGE>   3

                                     PART II
                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.

         The following table sets forth the costs and expenses in connection
with the sale and distribution of the securities being registered, other than
underwriting discounts and commissions. All of the amounts shown are estimates
except the Securities and Exchange Commission registration fees and Nasdaq
filing fee.

<TABLE>
<CAPTION>
                                                                        To be Paid
                                                                          By The
                                                                        Registrant
                                                                        ----------
<S>                                                                      <C>    
SEC Registration Fee ..................................                  $ 2,544
Nasdaq filing fee .....................................                  $17,500
Accounting fees and expenses ..........................                  $ 7,000
Legal fees and expenses ...............................                  $15,000
Miscellaneous expenses ................................                  $ 2,956

         Total ........................................                  $45,000
                                                                         =======

</TABLE>

- -------------------

ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

         As permitted by Section 204 of the California Corporations Code (the
"CCC"), the Registrant's Articles of Incorporation provide that each person who
is or was or who had agreed to become a director or officer of the Registrant or
who had agreed at the request of the Registrant's Board of Directors or an
officer of the Registrant to serve as an employee or agent of the Registrant or
as a director, officer, employee or agent of another corporation, partnership,
joint venture, trust or other enterprise, shall be indemnified by the Registrant
to the full extent permitted by the CCC or any other applicable laws. Such
Articles of Incorporation also provide that no amendment or repeal of such
Articles shall apply to or have any effect on the right to indemnification
permitted or authorized thereunder for or with respect to claims asserted before
or after such amendment or repeal arising from acts or omissions occurring in
whole or in part before the effective date of such amendment or repeal.

         The Registrant's Bylaws provide that the Registrant shall indemnify to
the full extent authorized by law any person made or threatened to be made a
party to an action or a proceeding, whether criminal, civil, administrative or
investigative, by reason of the fact that he, his testator or intestate was or
is a director, officer or employee of the Registrant or any predecessor of the
Registrant or serves or served any other enterprise as a director, officer or
employee at the request of the Registrant or an predecessor of the Registrant.
The Registrant's Bylaws also provide that the Registrant may enter into one or
more agreements with any person which provides for indemnification greater or
different than that provided in such Articles of Incorporation.

         The Registrant has entered into indemnification agreements with its
directors and certain of its officers.

         The Registrant intends to purchase and maintain insurance on behalf of
any person who is a director or officer against any loss arising from any claim
asserted against him and incurred by him in any such capacity, subject to
certain exclusions.

         See also the undertakings set out in response to Item 17 herein.

                                      II-1

<PAGE>   4

ITEM 16.  EXHIBITS.

         The following exhibits are filed with this Registration Statement:

<TABLE>
<CAPTION>
      EXHIBIT NO.                 DESCRIPTION OF EXHIBIT
      ----------- --------------------------------------------------------------

<S>               <C>                                                  
          5.1**   Opinion of Gray Cary Ware & Freidenrich LLP.

         10.1*    Structured Equity Line Flexible Financing(SM) Agreement by and
                  between the Company and Cheyenne LLC dated as of June 30,
                  1998.

         10.2*    Warrant to purchase up to 200,000 shares of Common Stock of
                  the Company issued to Cheyenne LLC dated as of June 30, 1998.

         10.3*    Registration Rights Agreement by and between the Company and
                  Cheyenne LLC dated as of June 30, 1998.

         23.1     Consent of Ernst & Young LLP, independent auditors.

         23.2**   Consent of Gray Cary Ware & Freidenrich LLP (included in
                  Exhibit 5.1).

         24.1**   Power of Attorney (included in the Signature Page contained in
                  Part II of the Registration Statement).
</TABLE>

 *       Incorporated by reference from the Company's Report on Form 8-K filed
         with the Commission on July 23, 1998.

**       Previously filed.

ITEM 17.  UNDERTAKINGS.

         A. The undersigned Registrant hereby undertakes:

                  (1) To file, during any period in which offers or sales are
being made, a post-effective amendment to this registration statement:

                           (i) To include any prospectus required by section
10(a)(3) of the Securities Act of 1933 (the "Securities Act");

                           (ii) To reflect in the prospectus any facts or events
arising after the effective date of the registration statement (or the most
recent post-effective amendment thereof) which, individually or in the
aggregate, represent a fundamental change in the information set forth in the
registration statement. Notwithstanding the foregoing, any increase or decrease
in volume of securities offered (if the total dollar value of securities offered
would not exceed that which was registered) and any deviation from the low or
high end of the estimated maximum offering range may be reflected in the form of
prospectus filed with the Commission pursuant to Rule 424(b) if, in the
aggregate, the changes in volume and price represent no more than a 20% change
in the maximum aggregate offering price set forth in the "Calculation of
Registration Fee" table in the effective registration statement;

                           (iii) To include any material information with
respect to the plan of distribution not previously disclosed in the registration
statement or any material change to such information in the registration
statement; provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not
apply if the information required to be included in a post-effective amendment
by those paragraphs is contained in periodic reports filed by the Registrant


                                      II-2

<PAGE>   5

pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934
that are incorporated by reference in the registration statement.

                  (2) That, for the purpose of determining any liability under
the Securities Act, each such post-effective amendment shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

                  (3) To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of the offering.

         B. Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers, and controlling persons
of the Registrant pursuant to the foregoing provisions, or otherwise, the
Registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer, or controlling
person of the Registrant in the successful defense of any action, suit, or
proceeding) is asserted by such director, officer, or controlling person in
connection with the securities being registered, the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.

         C. The undersigned Registrant hereby undertakes that:

                  (1) For the purposes of determining any liability under the
Securities Act, the information omitted from the form of prospectus filed as
part of this registration statement in reliance upon Rule 430A and contained in
a form of prospectus filed by the Registrant pursuant to Rule 424(b)(1) or (4)
or 497(h) under the Securities Act shall be deemed to be part of the
registration statement as of the time it was declared effective.

                  (2) For the purposes of determining any liability under the
Securities Act, each post-effective amendment that contains a form of prospectus
shall be deemed to be a new registration statement relating to the securities
offered therein, and the offering of such securities at that time shall be
deemed to be the initial bona fide offering thereof.


                                      II-3

<PAGE>   6

                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-2 and has duly caused this Amendment
No. 2 to registration statement to be signed on its behalf by the undersigned,
thereunto duly authorized in the City of San Mateo, State of California on
September 14, 1998.

                                        SCICLONE PHARMACEUTICALS, INC.



                                        By: /s/ Donald R. Sellers
                                           -------------------------------------
                                           Donald R. Sellers
                                           President and Chief Executive Officer


         Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated:


<TABLE>
<CAPTION>
      SIGNATURE                                              TITLE                                 DATE
      ---------                                              -----                                 ----
<S>                                           <C>                                               <C> 
 /s/ Donald R. Sellers
- --------------------------------------
Donald R. Sellers                             President, Chief Executive Officer and            September 14, 1998
                                              Director (Principal Executive Officer)
 /s/ Jere E. Goyan
- --------------------------------------
Jere E. Goyan, Ph.D.*                         Chairman of the Board and Director                September 14, 1998

 /s/ Diane Lee
- --------------------------------------
Diane Lee*                                    Director, Corporate Finance and Administration    September 14, 1998
                                              (Principal Financial and Accounting Officer)
 /s/ John D. Baxter
- --------------------------------------
John D. Baxter, M.D.*                         Director                                          September 14, 1998

 /s/ Edwin C. Cadman
- --------------------------------------
Edwin C. Cadman, M.D.*                        Director                                          September 14, 1998

/s/ Rolf H. Henel
- --------------------------------------
Rolf H. Henel*                                Director                                          September 14, 1998


*By:  /s/ Donald R. Sellers
      --------------------------------
      Donald R. Sellers,                                                                        September 14, 1998    
      Attorney-in-fact

</TABLE>

                                      II-4

<PAGE>   7






                               INDEX TO EXHIBITS

<TABLE>
<CAPTION>
      EXHIBIT NO.                 DESCRIPTION OF EXHIBIT
      ----------- --------------------------------------------------------------

<S>               <C>                                                  
          5.1**   Opinion of Gray Cary Ware & Freidenrich LLP.

         10.1*    Structured Equity Line Flexible Financing(SM) Agreement by and
                  between the Company and Cheyenne LLC dated as of June 30,
                  1998.

         10.2*    Warrant to purchase up to 200,000 shares of Common Stock of
                  the Company issued to Cheyenne LLC dated as of June 30, 1998.

         10.3*    Registration Rights Agreement by and between the Company and
                  Cheyenne LLC dated as of June 30, 1998.

         23.1     Consent of Ernst & Young LLP, independent auditors.

         23.2**   Consent of Gray Cary Ware & Freidenrich LLP (included in
                  Exhibit 5.1).

         24.1**   Power of Attorney (included in the Signature Page contained in
                  Part II of the Registration Statement).
</TABLE>

 *       Incorporated by reference from the Company's Report on Form 8-K filed
         with the Commission on July 23, 1998.

**       Previously filed.



<PAGE>   1
                                                                    EXHIBIT 23.1


               CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS

We consent to the reference to our firm under the caption "Experts" in the
Registration Statement on Form S-2, Amendment No. 1 and related Prospectus of
SciClone Pharmaceuticals, Inc. for the registration of 3,000,000 shares of its
Common Stock and to the incorporation by reference therein of our report dated
January 16, 1998, except Note 10, as to which date is April 2, 1998, with
respect to the consolidated financial statements and schedule of SciClone
Pharmaceuticals, Inc. included in its Annual Report on Form 10-K/A for the year
ended December 31, 1997 filed with the Securities and Exchange Commission.


/s/ Ernst & Young LLP

Palo Alto, California
September 8, 1998








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