INVESCO GLOBAL HEALTH SCIENCES FUND
N-2/A, 1999-05-24
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            AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 24, 1999

                                          1933 ACT FILE NO.  33-75831
                                          1940 ACT FILE NO.  811-06476


                     U.S. SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM N-2
                        (CHECK APPROPRIATE BOX OR BOXES)


[X] REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
[X] Pre-Effective Amendment No. 1
[ ] Post-Effective Amendment No.


                                       AND

[X]  REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940
[X]  Amendment No. 1

                       INVESCO GLOBAL HEALTH SCIENCES FUND
                             7800 EAST UNION AVENUE
                             DENVER, COLORADO 80237
                     ADDRESS OF PRINCIPAL EXECUTIVE OFFICES

                                 1-303-930-6300
               REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE

                               Glen A. Payne, Esq.
                                 General Counsel
                            INVESCO Funds Group, Inc.
                         7800 E. Union Avenue, Suite 800
                             Denver, Colorado 80237
     NAME AND ADDRESS (NUMBER, STREET, STATE, ZIP CODE) OF AGENT FOR SERVICE

                                   COPIES TO:


             Thomas A. Hale                       Clifford J. Alexander
         Skadden, Arps, Slate,                 Kirkpatrick & Lockhart LLP
       Meagher & Flom (Illinois)                1800 Massachusetts Avenue
   333 West Wacker Drive, Suite 2100                  Second Floor
        Chicago, Illinois 60606                   Washington, DC 20036


APPROXIMATE  DATE OF PROPOSED  PUBLIC  OFFERING:  As soon as  practicable  after
the effective date of this Registration Statement.

      If any  securities  being  registered  on this form will be  offered  on a
delayed or continuous  basis in reliance on Rule 415 under the Securities Act of
1933, other than securities  offered in connection with a dividend  reinvestment
plan, check the following box. [ ]




<PAGE>


        CALCULATION OF REGISTRATION FEE UNDER THE SECURITIES ACT OF 1933
<TABLE>
<CAPTION>
<S>                        <C>            <C>               <C>          <C>

                                                            PROPOSED
                                             PROPOSED       MAXIMUM
                                             MAXIMUM        AGGREGATE      AMOUNT OF
TITLE OF SECURITIES        AMOUNT BEING   OFFERING PRICE    OFFERING     REGISTRATION
 BEING REGISTERED          REGISTERED(1)   PER UNIT(2)      PRICE(2)        FEE(2)
- -------------------------------------------------------------------------------------


Shares of Beneficial
Interest Issuable Upon
Exercise of Rights to
Subscribe for Such Shares  7,601,529 shares   $17 19/32     $133,739,400   $37,179.55(3)
- ----------------------------------------------------------------------------------------
</TABLE>

(1) Includes 1,20,306  shares of beneficial interest to cover an increase by the
    Registrant of 25% of the number  of shares of beneficial interest subject to
    subscriptions.

(2) Estimated  solely  for the  purpose of  calculating the  registration fee in
    accordance with Rule 457(c) under the Securities Act of 1933 on the basis of
    the average of the high and  low sales prices for the Fund's shares reported
    on the New York Stock Exchange on May 19, 1999.

(3) A  $5,334.13  registration   fee  accompanied  the  Fund's  April  7,   1999
    Registration Statement  that was  submitted to the  Securities and  Exchange
    Commission.


THE REGISTRANT HEREBY AMENDS THIS  REGISTRATION  STATEMENT ON SUCH DATE OR DATES
AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE  DATE UNTIL  REGISTRANT  SHALL FILE A
FURTHER AMENDMENT WHICH  SPECIFICALLY  STATES THAT THIS  REGISTRATION  STATEMENT
SHALL  THEREAFTER  BECOME  EFFECTIVE  IN  ACCORDANCE  WITH  SECTION  8(a) OF THE
SECURITIES ACT OF 1933, AS AMENDED,  OR UNTIL THE  REGISTRATION  STATEMENT SHALL
BECOME EFFECTIVE ON SUCH DATE AS THE SECURITIES AND EXCHANGE COMMISSION,  ACTING
PURSUANT TO SECTION 8(a), MAY DETERMINE.














                                       ii
<PAGE>

                       INVESCO GLOBAL HEALTH SCIENCES FUND
                              CROSS-REFERENCE SHEET

PART A

ITEM NO.   CAPTION                                LOCATION IN PROSPECTUS
- --------   -------                                ----------------------

1.         Outside Front Cover                    Front Cover Page.
2.         Inside Front and Outside Back Cover    Front Cover Page.
           Page
3.         Fee Table and Synopsis                 Prospectus Summary; and Fee
                                                  Table.
4.         Financial Highlights                   Financial Highlights.
5.         Plan of Distribution                   Front Cover Page; Prospectus
                                                  Summary; The Offer; Dividends
                                                  and Other Distributions; and
                                                  Dividend Reinvestment and
                                                  Cash Purchase Plan.
6.         Selling Shareholders                   Not Applicable.
7.         Use of Proceeds                        Prospectus Summary; and Use
                                                  of Proceeds.
8.         General Description of the Registrant  Front Cover Page; Prospectus
                                                  Summary; Financial Highlights
                                                  - Portfolio Characteristics
                                                  and Composition; Trading and
                                                  Net Asset Value Information;
                                                  The Fund; The Offer;
                                                  Description of Shares of
                                                  Beneficial Interest;
                                                  Investment Objective and
                                                  Policies; Risk Factors and
                                                  Special Considerations;
                                                  Investment Restrictions; and
                                                  Special Investment Practices.
9.         Management                             Prospectus Summary;
                                                  Management of the Fund; and
                                                  Custodian, Transfer Agent,
                                                  Dividend Disbursing Agent,
                                                  and Registrar.
10.        Capital Stock, Long-Term Debt, and     Front Cover Page; Description
           Other Securities                       of Shares of Beneficial
                                                  Interest; Dividends and Other
                                                  Distributions; Dividend
                                                  Reinvestment and Cash Purchase
                                                  Plan; and Federal Taxation Of
                                                  The Fund And Its Shareholders.
11.        Defaults and Arrears on Senior         Not Applicable.
           Securities
12.        Legal Proceedings                      Not Applicable.
13.        Table of Contents of the Statement of  Table of Contents of
           Additional Information                 Statement of Additional
                                                  Information.

PART B

ITEM NO.   CAPTION                                 LOCATION IN STATEMENT OF
- --------   -------                                 ADDITIONAL INFORMATION
                                                   ----------------------

14.        Cover Page                              Cover Page.
15.        Table of Contents                       Table of Contents.
16.        General Information and History         General Information.


                                       iii
<PAGE>

ITEM NO.   CAPTION                                 LOCATION IN STATEMENT OF
- --------   -------                                 ADDITIONAL INFORMATION
                                                   ----------------------
17.        Investment Objective and Policies       Additional Information About
                                                   Its Investment Objective and
                                                   Policies; Investment
                                                   Restrictions.
18.        Management                              Management.

19.        Control Persons and Principal Holders   Ownership of Shares; and
           of Securities                           Prospectus: Description of
                                                   Shares of Beneficial
                                                   Interest.
20.        Investment Advisory and Other Services  Management; Financial
                                                   Statements; Prospectus:
                                                   Management of the Fund;
                                                   Prospectus: Custodian,
                                                   Transfer Agent, Dividend
                                                   Disbursing Agent, and
                                                   Registrar; and Prospectus:
                                                   Independent Accountants.
21.        Brokerage Allocation and Other          Portfolio Transactions;
           Practices                               Prospectus: Portfolio
                                                   Trading; and Prospectus:
                                                   Special Investment Practices.
22.        Tax Status                              Taxation.
23.        Financial Statements                    Financial Statements.

PART C

Information required to be included in Part C is set forth under the appropriate
item, so numbered, in Part C of this Registration Statement.




                                       iv
<PAGE>


                       INVESCO GLOBAL HEALTH SCIENCES FUND
              6,081,223 SHARES OF BENEFICIAL INTEREST ISSUABLE UPON
                 EXERCISE OF RIGHTS TO SUBSCRIBE FOR SUCH SHARES

INVESCO  Global Health  Sciences  Fund (the "Fund") is issuing  non-transferable
rights ("Rights") to its shareholders of record ("Record Date  Shareholders") as
of the close of business on May 25, 1999 (the "Record Date").  These Rights will
allow Record Date  Shareholders to subscribe for 6,081,223  shares of beneficial
interest of the Fund  ("Shares"),  subject to the limitations  discussed in this
prospectus (the  "Prospectus").  Record Date Shareholders will receive one Right
for every five  outstanding  Shares they own on the Record Date. Each Right that
Record Date Shareholders  receive may be exercised to buy one new Share.  Record
Date  Shareholders who exercise all of their Rights may request to subscribe for
the Shares  not  acquired  by other  Record  Date  Shareholders  in this  Rights
offering (the "Offer" or this  "Offering").  The Fund may increase the number of
Shares that may be  subscribed  for in this  Offering by up to 25% of the Shares
offered or up to an  additional  1,520,306  Shares,  for an  aggregate  total of
7,601,529 Shares, to honor requests for additional  Shares. On MAY 21, 1999, the
last reported net asset value ("NAV") per Share was $18.63 and the last reported
sales  price of a Share on the New York  Stock  Exchange  ("NYSE")  was  $16.69.
Unless extended by the Fund, this Offer will expire at 5:00 p.m. Eastern time on
June 18, 1999 ("Expiration Date"). The currently  outstanding Shares are listed,
and the Shares  issued in this  Offering  will be listed,  on the NYSE under the
symbol "GHS."


THE PURCHASE PRICE PER SHARE (THE "SUBSCRIPTION PRICE") WILL BE 95% OF THE LOWER
OF: (1) THE  AVERAGE OF THE LAST  REPORTED  SALES PRICE PER SHARE ON THE NYSE ON
THE  EXPIRATION  DATE AND ON THE PRECEDING  FOUR  BUSINESS  DAYS; OR (2) THE NET
ASSET VALUE ("NAV") PER SHARE ON THE EXPIRATION DATE.

                   -----------------------------------------

NEITHER THE SECURITIES AND EXCHANGE  COMMISSION (THE "SEC" OR "COMMISSION")  NOR
ANY STATE SECURITIES  COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES
OR DETERMINED THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO
THE CONTRARY IS A CRIMINAL OFFENSE.

<TABLE>
<CAPTION>


                              PER SHARE  TOTAL


<S>                               <C>    <C>           <C>
Estimated Subscription Price      $16.53               Calculated as of May 21, 1999, using the Subscription Price
                                                       formula rounded to the $0.05.


Sales Load                        3.75%  3.75%
                                  $15.69 $95,436,172
                                  $15.69 $119,295,219

Net Proceeds to the Fund*                        Purchase of all 6,081,223 Shares in the Primary Subscription

Net Proceeds to the Fund*                        Full Primary Subscription and 25% Over-Allotment (7,601,529 Shares)
</TABLE>





*TOTAL OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.............$ 596,200

Record Date  Shareholders  who do not exercise  their Rights  should expect that
they will, at the completion of the Offer, own a smaller  proportional  interest
in the Fund than they would if they  exercised  their Rights.  In addition,  the
Subscription  Price  per  Share  will be less  than  the  NAV per  Share  on the
Expiration  Date.  Therefore,  the  completion  of the Offer  will  result in an
immediate  dilution  of  NAV  per  Share,  that  may  be  significant,  for  all
shareholders.  This will disproportionately affect those shareholders who do not
exercise  their Rights in full.  The Fund cannot state  precisely  the extent of
this  dilution  at this time,  because  certain  terms of the  Offer,  which are
specified  within this Prospectus,  have not been determined.  See "Risk Factors
and Special Considerations--Dilution."

This  Prospectus  sets forth  concisely  the  information  about the Fund that a
prospective  investor ought to know before  investing.  Investors are advised to
read and retain it for future reference.  A Statement of Additional  Information
(the "SAI") dated May 25, 1999 containing additional  information about the Fund
has been filed with the SEC and is  incorporated  by  reference  in its entirety
into this Prospectus.  A copy of the SAI, the table of contents of which appears
on page 51 of this  Prospectus,  may be obtained  without  charge by calling the
Fund at 1-800-528-8765 or by contacting the Fund at 7800 E. Union Avenue,  Suite
800, Denver,  Colorado 80237. In addition, a copy of the SAI, and other material
incorporated  herein by  reference,  may be obtained  from the SEC's  website at
http://www.sec.gov.


                              --------------------
                            PAINEWEBBER INCORPORATED
                              --------------------


                  THE DATE OF THIS PROSPECTUS IS MAY 24, 1999.




<PAGE>

                               PROSPECTUS SUMMARY

THIS SUMMARY  HIGHLIGHTS SOME INFORMATION THAT IS DESCRIBED MORE FULLY ELSEWHERE
IN THIS PROSPECTUS.  IT MAY NOT CONTAIN ALL OF THE INFORMATION THAT IS IMPORTANT
TO YOU. TO  UNDERSTAND  THE OFFER  FULLY,  YOU SHOULD  READ THE ENTIRE  DOCUMENT
CAREFULLY,  INCLUDING  THE RISK  FACTORS  UNDER THE  HEADING  "RISK  FACTORS AND
SPECIAL CONSIDERATIONS."


PURPOSE OF THE OFFER       The  Board of  Trustees  of the Fund  (the  "Board of
                           Trustees"  or the  "Board")  has  determined  that it
                           would  be in the best  interests  of the Fund and its
                           existing  shareholders  to increase the Fund's assets
                           so  that  it  may be in a  better  position  to  take
                           advantage of  investment  opportunities  and increase
                           the  diversification of its portfolio while achieving
                           other net benefits to the Fund.

                           In reaching  its  decision to approve the Offer,  the
                           Board of Trustees  considered,  among  other  things,
                           advice by INVESCO Funds Group,  Inc. (the "Investment
                           Manager" or "INVESCO"),  that the availability of new
                           assets  would  enable  the Fund to pursue  attractive
                           investments without selling portfolio securities.  In
                           addition,  the Board of  Trustees  considered  that a
                           rights  offering  could result in more  liquidity for
                           the Shares,  would give  shareholders the opportunity
                           to purchase  Shares at a price below market value per
                           Share  and/or NAV per Share,  and might  increase the
                           level of market  interest in the Fund. The Board also
                           believes  that  this  Offer  may  result in a nominal
                           decrease in the Fund's operating  expense ratio. This
                           is because the Fund's  fixed costs can be spread over
                           a larger asset base.  In  addition,  the Fund and the
                           Investment   Manager   recently   agreed   to  add  a
                           breakpoint to the investment management agreement for
                           assets  in  excess  of $500  million.  At the  Fund's
                           current asset size, substantially all of the Proceeds
                           of the Offer  would be  managed  at this  lower  fee,
                           which  would have the effect of  lowering  the Fund's
                           overall expense ratio.


                           In  determining  that  the  Offer  was  in  the  best
                           interests of the Fund and its shareholders, the Board
                           of Trustees  retained  PaineWebber  Incorporated (the
                           "Dealer  Manager") to provide the Fund with financial
                           advisory  and  marketing  services  relating  to  the
                           Offer,  including the structure,  timing and terms of
                           the Offer. In addition to the foregoing, the Board of
                           Trustees considered, among other things, the benefits
                           and drawbacks of conducting a non-transferable versus
                           a transferable  rights offering,  the possible impact
                           of the Offer on market price volatility, its dilutive
                           effect,  its effect on  non-exercising  shareholders,
                           the   effect   on   the   Fund   if  the   Offer   is
                           under-subscribed,  and the  experience  of the Dealer
                           Manager in conducting rights offerings.

                                       1
<PAGE>


IMPORTANT TERMS OF THE     Total number of Shares               7,539,029*
OFFER                      offered:

                           Number of non-transferable     One  Right  for  every
                           Rights issued to each Record   five Shares  owned  on
                           Date Shareholder:              the   Record      Date

                           Subscription ratio:            One  Share  for  every
                                                          one Right


                           Subscription Price:            95%  of  the lower  of
                                                          (1) the average of the
                                                          last   reported  sales
                                                          price per Share on the
                                                          NYSE on the Expiration
                                                          Date   and   on    the
                                                          preceding         four
                                                          business   days**   or
                                                          (2) the NAV per  Share
                                                          on the Expiration Date

                           Expiration Date:               The Offer will  expire
                                                          at 5:00  P.M.  Eastern
                                                          time  June  18,  1999,
                                                          unless  the  Offer  is
                                                          extended  to a date no
                                                          later  than  June  21,
                                                          1999

                           *  Includes 1,520,306 Shares  that the Fund may issue
                           to cover over-subscription requests.

                           **  "Business  Day" is any day on  which  the NYSE is
                           open for trading.

OVER-SUBSCRIPTION          Record Date  Shareholders  who fully  exercise all of
PRIVILEGE                  the Rights  issued to them are entitled to request to
                           subscribe for those Shares  offered  hereby that were
                           not  bought by other  Record  Date  Shareholders.  If
                           enough Shares are  available,  all such requests will
                           be  honored  in full.  If such  requests  for  Shares
                           exceed the  Shares  available,  the Fund may,  at the
                           discretion of the Board of Trustees,  issue Shares up
                           to an additional 25% of the Shares available pursuant
                           to the Offer (up to an additional  1,520,306  Shares)
                           in  order  to  cover  such  requests.  Regardless  of
                           whether the Fund issues such additional  Shares,  and
                           to the extent  Shares are not  available to honor all
                           requests,  the available Shares will be allocated PRO
                           RATA  among  those  who  over-subscribe  based on the
                           number  of  Rights  originally  issued to them by the
                           Fund.

IMPORTANT DATES TO         EVENT                              DATE
  REMEMBER

                           Record Date                        May 25, 1999

                           Subscription Period                May 25 - June 18,
                                                              1999*


                                       2
<PAGE>

                           Expiration Date and Pricing Date   June 18, 1999*

                           Subscription Certificates and      June 18, 1999*
                           Payment for Shares Due**

                           Notice of Guaranteed Delivery Due  June 18, 1999*

                           Payment for Guarantees of          June 23,  1999*
                           Delivery Due

                           Confirmation Mailed to             June 30, 1999*
                           Participants

                           Final Payment for Shares***        July 12, 1999*

                           *   Unless the Offer is  extended to a  date no later
                               than June 21, 1999.

                           **  A Record Date Shareholder  exercising Rights must
                               deliver  by  the  Expiration  Date  either  (i) a
                               Subscription   Certificate  (defined  below)  and
                               payment for Shares or (ii) a Notice of Guaranteed
                               Delivery (defined below).

                           *** Additional   amount   due  (in   the   event  the
                               Subscription    Price   exceeds   the   Estimated
                               Subscription Price).

NON-TRANSFERABILITY OF     The Rights are non-transferable  and, therefore,  may
  RIGHTS                   not be  purchased  or sold.  The  Rights  will not be
                           listed   for   trading  on  the  NYSE  or  any  other
                           securities exchange. However, the Shares to be issued
                           pursuant  to the Offer will be listed for  trading on
                           the NYSE, subject to notice of issuance.

METHOD OF EXERCISING       Except as described below,  subscription certificates
   RIGHTS                  evidencing    the    Rights    (the     "Subscription
                           Certificates")   will   be  sent   to   Record   Date
                           Shareholders  or  their  broker,  bank, custodian, or
                           other nominee.  If a  Record Date Shareholder  wishes
                           to exercise Rights, the shareholder may  do so in the
                           following ways:


                           (1) Record Date Shareholders or their nominees should
                               complete and  sign the  Subscription  Certificate
                               and  mail  it in the envelope provided or deliver
                               it  with  payment  in  full to EquiServe, Inc. at
                               the address indicated   on    the    Subscription
                               Certificate.  A completed and signed Subscription
                               Certificate  and payment  must be received by the
                               Expiration Date; or

                           (2) Contact  your  broker, banker or  trust  company,
                               which can guarantee,  on your behalf, payment and
                               delivery  of a properly  completed  and  executed
                               Subscription Certificate by the close of business
                               on the third  Business  Day after the  Expiration
                               Date pursuant to a notice of guaranteed  delivery
                               ("Notice of Guaranteed  Delivery").  A fee may be
                               charged   for  this   service.   The   Notice  of
                               Guaranteed Delivery, however, must be received on
                               or before the Expiration Date.


                                       3
<PAGE>


OFFERING FEES AND          The Fund  has agreed to pay  the Dealer Manager a fee
  EXPENSES                 ("Dealer Manager Fee") for its financial advisory and
                           marketing  services  equal to 1.25% of the  aggregate
                           Subscription  Price for each Share issued pursuant to
                           the  Offer,  and the  Fund  has  also  agreed  to pay
                           broker-dealers,  including the Dealer  Manager,  fees
                           for their solicitation efforts  ("Solicitation Fees")
                           of 2.50% of the Subscription Price per Share for each
                           Share issued pursuant to the Offer. Solicitation Fees
                           will be paid to the  broker-dealer  designated on the
                           applicable  portion of the  Subscription  Certificate
                           or, in the  absence of any such  designation,  to the
                           Dealer Manager.  Other offering  expenses incurred by
                           the Fund are estimated at $596,200, which includes up
                           to $100,000 that may be paid to the Dealer Manager as
                           partial  reimbursement  for its expenses  relating to
                           the Offer.


FOREIGN RESTRICTIONS       Record Date  Shareholders  whose record addresses are
                           outside  the  United  States  will  receive   written
                           notice   of   the   Offer;   however,    Subscription
                           Certificates    will   not   be    mailed   to   such
                           shareholders.    The    Rights    to   which    those
                           Subscription  Certificates relate will be held by the
                           subscription  agent  for  such  foreign  Record  Date
                           Shareholders'   accounts   until   instructions   are
                           received  in writing  with  payment to  exercise  the
                           Rights.  If no such  instructions are received by the
                           Expiration   Date,  such  Rights  will  expire.   See
                           "Subscription Agent."


USE OF PROCEEDS            The  Investment  Manager has advised the Fund that it
                           anticipates  that the proceeds ("Proceeds")  will  be
                           invested   in   accordance   with   its    investment
                           objective   and   the   policies   set  forth   under
                           "Investment   Objective  and Policies"  within  three
                           months from  the  date of this Prospectus  (but in no
                           event  later than six  months from  the date of  this
                           Prospectus),  depending  on market    conditions  and
                           the    availability   of     appropriate  securities.
                           Pending   such   investment, the  Proceeds   will  be
                           invested  in  certain  high  quality  short-term debt
                           instruments,  or  in   certain  other     investments
                           (including,  potentially,  futures  contracts  on the
                           Standard  & Poor's  500  Composite Stock Price  Index
                           ("S&P  500  futures")  as  described   herein   under
                           "Investment    Objective    and     Policies--Special
                           Investment Practices--Hedging."


                                       4
<PAGE>

INFORMATION AGENT          Please direct all questions or  inquiries relating to
                           the Offer to the Fund's information agent as follows:


                                 SHAREHOLDER COMMUNICATIONS CORP.
                                 17 STATE STREET
                                 NEW YORK, NY 10004
                                 (800) 722-4072
                                 BROKERS AND BANKS, PLEASE CALL (212)-805-7113


                           Shareholders may also contact their broker or nominee
                           for information.


INFORMATION REGARDING THE  The  Fund  is a  diversified,  closed-end  management
  FUND                     investment  company  registered  under the Investment
                           Company Act of 1940, as amended  ("1940 Act").  It is
                           managed  by  INVESCO.  The  Fund was  organized  as a
                           Massachusetts business trust on November 18, 1991 and
                           commenced investment  operations on January 24, 1992.
                           The Fund is aggressively managed for growth. It seeks
                           to achieve its objective by investing its assets in a
                           broad range of health care related  securities,  such
                           as market-leading  pharmaceutical companies,  medical
                           devices   manufacturers   and   suppliers,    biotech
                           companies,   health  care  delivery  companies,   and
                           various private placement  investments.  The Fund may
                           further  focus its  investments  in  certain of these
                           sectors. For example, at the date of this Prospectus,
                           approximately 60% of the Fund's portfolio is invested
                           in   equity   securities   of  large   pharmaceutical
                           companies.  The Fund may purchase and sell options on
                           equities.  See "The Fund" and  "Investment  Objective
                           and Policies." For  information  regarding the Fund's
                           portfolio characteristics and composition as of April
                           30,  1999,   see   "Portfolio   Characteristics   and
                           Composition."

INFORMATION REGARDING THE  INVESCO has served as the Fund's  investment  adviser
  MANAGER                  since  February  4,  1998.   INVESCO  determines  the
                           composition  of  the  Fund's  portfolio,  places  all
                           orders for the  purchase and sale of  securities  and
                           for other  transactions,  oversees the  settlement of
                           the   Fund's    securities   and   other    portfolio
                           transactions, and provides administrative services to
                           the  Fund  described  below  in  "Management  of  the
                           Fund--Investment Manager."

                           As compensation for its services to the Fund, INVESCO
                           receives an  investment  management  fee that accrues
                           daily at the applicable rate and is paid monthly.  On
                           February 3, 1998,  the Board of Trustees  and INVESCO
                           agreed  to  add  a  breakpoint   to  the   investment
                           management fee, such that the Fund pays INVESCO a fee
                           at the  annual  rate of  1.00% on the  Fund's  ending
                           daily net assets up to and  including  $500  million,
                           and 0.90% on the  Fund's  ending  daily net assets in
                           excess of $500 million.  Additionally,  in accordance
                           with  an  administrative  agreement,  the  Fund  pays
                           INVESCO a monthly  fee at the annual rate of 0.10% on
                           the Fund's ending daily net assets for administrative
                           services.  Prior to February 4, 1998,  INVESCO  Trust
                           Company  ("ITC"),  then a wholly owned  subsidiary of


                                       5
<PAGE>


                           INVESCO, served as the Fund's investment adviser.

RISK FACTORS AND SPECIAL   The following  summarizes some  of the  matters  that
  CONSIDERATIONS           you  should  consider  before investing  in the  Fund
                           through  this  Offer.  Please see "Risk  Factors  and
                           Special Considerations" of this Prospectus for a more
                           complete discussion of these matters.


                           DILUTION: NET ASSET VALUE AND OWNERSHIP.  Record Date
                           Shareholders  will experience an immediate  dilution,
                           which may be  significant,  of the  aggregate  NAV of
                           their  Shares  as a result of the  completion  of the
                           Offer.  This is because  the  Subscription  Price per
                           Share  will be less  than  the NAV per  Share  on the
                           Expiration  Date,  the Fund will  incur  expenses  in
                           connection  with the Offer,  and the number of Shares
                           outstanding  after  the  Offer  will  increase  in  a
                           greater  percentage  than the increase in the size of
                           the Fund's  assets.  This  dilution  also will affect
                           those shareholders to a greater extent if they do not
                           exercise  their  Rights  in  full.  In  addition,  if
                           shareholders do not fully exercise their Rights, they
                           will, as a result of the completion of the Offer, own
                           a  smaller  proportional  interest  in the Fund  than
                           would  otherwise  be  the  case.  Although  it is not
                           possible  to  state   precisely  the  amount  of  any
                           dilution,  either for NAV or in ownership  interests,
                           because it is not known at this time what the NAV per
                           Share will be on the Expiration Date, what proportion
                           of  the  Rights  will  be  exercised,   or  what  the
                           Subscription  Price will be, such  dilution  could be
                           significant.  For a  more  detailed  discussion,  see
                           "Risk Factors and Special Considerations--Dilution."

                           HEALTH   SCIENCE   COMPANIES.   Investment   in   the
                           securities  of companies  principally  engaged in the
                           development,  production or  distribution of products
                           or services  relating to the health sciences ("Health
                           Science  Companies")  entails special  considerations
                           and risks.  Among  these is the risk that many Health
                           Science  Companies  may be subject  to, and  possibly
                           adversely  affected  by,  some  of  the  same  trends
                           relating  to the demand for  health-related  products
                           and  services and the same  regulatory,  economic and
                           political factors.  Certain health science industries
                           and Health Science  Companies are  characterized by a
                           single product focus,  rapidly changing technology or
                           extensive  government   regulation.   Many  of  these
                           activities  are funded or  subsidized  by federal and
                           state   governments;   consequently,   withdrawal  or
                           curtailment  of this  support  could  have an adverse
                           impact on the  profitability,  and market prices,  of
                           such companies. Continuing technological advances may
                           mean rapid  obsolescence  of products  and  services.
                           These regulatory and research developments may result
                           in abrupt fluctuations in securities values of Health
                           Science  Companies.  In addition,  smaller developing
                           Health  Science  Companies  may  require   additional
                           capital  investments,  which may dilute the interests
                           of existing  investors,  such as the Fund. For a more
                           detailed discussion, see "Risk Factors-Health Science
                           Companies."


                                       6
<PAGE>

                           INVESTMENTS  IN  UNSEASONED  COMPANIES.  The Fund may
                           invest in the  securities  of smaller,  less seasoned
                           companies.  These  investments  may  present  greater
                           opportunities  for  growth but also  involve  greater
                           risks  than   those   customarily   associated   with
                           investments   in  securities   of  more   established
                           companies.  Some of the Health  Science  Companies in
                           which the Fund may invest will be start-up  companies
                           that may have  insubstantial  operational or earnings
                           history  or  may  have  limited  products,   markets,
                           financial  resources or  management  depth.  Some may
                           also  be  emerging  companies  at  the  research  and
                           development stage with no products or technologies to
                           market  or  approved  for  marketing.  Securities  of
                           emerging Health Science  Companies may lack an active
                           secondary market and may be subject to more abrupt or
                           erratic price  movements  than  securities of larger,
                           more  established  companies or stock market averages
                           in general.  Competitors  of certain  Health  Science
                           Companies,  which  may or may not be  Health  Science
                           Companies,  may have substantially  greater financial
                           resources  than  many of the  companies  in which the
                           Fund may  invest.  See "Risk  Factors-Investments  in
                           Unseasoned  Companies"  and  "Risk   Factors-Illiquid
                           Investments."

                           SUBSTANTIAL  COMPETITION.  Intense competition exists
                           within and among certain health  science  industries,
                           including   competition   to   obtain   and   sustain
                           proprietary  technology  protection.  Health  Science
                           Companies may be highly  dependent on the strength of
                           a patent to maintain  revenues and market share.  The
                           complex nature of the technologies  involved can lead
                           to patent disputes,  including  litigation that could
                           result in a company  losing an  exclusive  right to a
                           patent. See "Risk Factors-Substantial Competition."

                           PRODUCT  LIABILITY  EXPOSURE.  Certain Health Science
                           Companies and related companies in which the Fund may
                           invest will be exposed to potential  liability  risks
                           that  are   inherent   in   testing,   manufacturing,
                           marketing   and   selling   human   therapeutic   and
                           diagnostic   products.   See  "Risk   Factors-Product
                           Liability Exposure."


                           FOREIGN   SECURITIES.   The  Fund   will   invest  in
                           securities of foreign  issuers and securities  traded
                           in foreign markets ("Foreign Securities").  Investing
                           in Foreign  Securities  involves  considerations  and
                           risks not  typically  associated  with  investing  in
                           securities of U.S. issuers in U.S.  markets.  Foreign
                           Securities  of many  non-U.S.  companies  may be less
                           liquid and their prices more volatile than securities
                           of comparable U.S. companies. The issuance of Foreign
                           Securities and brokers are generally  subject to less
                           governmental   the  activities  of  supervision   and
                           regulation  than  U.S.  securities  and  brokers  and
                           foreign accounting,  auditing and financial reporting
                           standards  differ  from  U.S.  standards,   and  less
                           information may be available about Foreign Securities
                           than U.S. securities.  For a more detailed discussion
                           about  some  of  the  other  risks   associated  with
                           investments   in   Foreign   Securities,   see  "Risk
                           Factors-Foreign Securities."



                                       7
<PAGE>

                           CURRENCY  RISK. The Fund may receive a portion of its
                           income  and  gains  in  currencies  other  than  U.S.
                           dollars,  although the Fund will make  dividends  and
                           other  distributions in U.S. dollars.  A reduction in
                           the value of such foreign currencies  relative to the
                           U.S.  dollar prior to  conversion  into U.S.  dollars
                           would  adversely   affect  the  Fund's  NAV  and  net
                           investment  income and capital  gains,  if any, to be
                           distributed  to  shareholders  of the Fund. See "Risk
                           Factors-Currency Risk."

                           ILLIQUID  INVESTMENTS.  The Fund may invest up to 25%
                           of its total assets in securities  for which there is
                           no readily available secondary market. Therefore, the
                           Fund's  ability  to sell  such  securities  at a fair
                           price may be impaired or delayed. In addition,  these
                           securities may exhibit greater price  volatility than
                           securities for which a secondary market exists. Since
                           its inception,  the Fund has  consistently  made such
                           investments. See "Risk Factors-Illiquid Investments."


                           JUNK BONDS AND UNRATED DEBT SECURITIES.  The Fund may
                           invest  up  to  10%  of  its  total  assets,  in  the
                           aggregate,  in  non-convertible  debt  securities  of
                           Health Science Companies and related companies. These
                           securities  and other  investments  in such companies
                           may include securities that have been rated as low as
                           C in the rating categories  established by Standard &
                           Poor's, a division of The McGraw-Hill Companies, Inc.
                           ("Standard & Poor's"), and Moody's Investors Service,
                           Inc. ("Moody's") or may be unrated if deemed to be of
                           comparable credit quality by the Investment  Manager.
                           These  securities,  which are commonly referred to as
                           "junk   bonds,"  are   regarded,   on   balance,   as
                           predominantly  speculative in terms of the ability of
                           the  issuer to pay  interest  or repay  principal  in
                           accordance  with  the  terms  of the  obligation  and
                           accordingly  involve more credit risk than securities
                           rated in the  higher  rating  categories.  For a more
                           detailed  discussion,  see "Risk  Factors--Junk Bonds
                           and Unrated Debt  Securities." Such securities may be
                           illiquid. See "Risk Factors--Illiquid Investments."

                           SPECIAL INVESTMENT PRACTICES. The Fund may make short
                           sales,  engage in certain  currency and other hedging
                           transactions, purchase securities on a when-issued or
                           a  delayed  delivery  basis,  enter  into  repurchase
                           agreements,  lend its portfolio securities and borrow
                           money to  repurchase  or make  tender  offers for its
                           Shares or for temporary purposes.  These transactions
                           involve certain risks and may result in losses to the
                           Fund. See "Investment Objective and Policies--Special
                           Investment Practices," "Investment Restrictions," and
                           "Description of Shares of Beneficial Interest--Tender
                           Offer or Repurchase of Shares."

                           NET  ASSET  VALUE  DISCOUNT.   Shares  of  closed-end
                           investment  companies  frequently trade at a discount
                           from their NAV (that is,  the market  price per share
                           is less than the value per share of the net  assets).
                           This  characteristic  is a risk separate and distinct
                           from the risk that the Fund's NAV will  decrease as a
                           result  of  its  investment   activities.   Moreover,
                           investors  expecting to sell their Shares  during the
                           course of the Offering  should be aware that there is



                                       8
<PAGE>


                           a greater risk that this discount, which may increase
                           during the Offering, will adversely affect them. This
                           increased  risk is because,  among other things,  the
                           market  price per Share may reflect  the  anticipated
                           dilution  to the Shares  that will  result  from this
                           Offering.   See  "Risk   Factors--Net   Asset   Value
                           Discount" and "Special Combination--Dilution."


                           ANTI-TAKEOVER PROVISIONS OF THE FUND'S DECLARATION OF
                           TRUST AND BY-LAWS. The Fund's Declaration of Trust as
                           amended on December 5, 1991  ("Declaration of Trust")
                           and By-Laws and any  amendments  thereto  ("By-Laws")
                           (together,  the  "Charter  Documents")  have  certain
                           "anti-takeover" provisions that could have the effect
                           of  limiting  (i) the  ability of other  entities  or
                           persons  to  acquire  control  of the Fund,  (ii) the
                           Fund's freedom to engage in certain transactions, and
                           (iii)  the   ability  of  the  Board  or  the  Fund's
                           shareholders  to amend the  Charter  Documents  or to
                           effect  changes  in  the  Fund's   management.   Such
                           provisions  also  may  dissuade  third  parties  from
                           making  offers to purchase  Shares at a premium  over
                           market   price.   See   "Description   of  Shares  of
                           Beneficial Interest-Certain  Anti-Takeover Provisions
                           of the Declaration of Trust and By-Laws."

                           YEAR  2000.   INVESCO   has   committed   substantial
                           resources and made significant progress toward making
                           sure its computer  systems  will  continue to operate
                           smoothly  through the year 2000 and expects  that its
                           business  partners also will be prepared for the year
                           2000. While INVESCO does not anticipate interruptions
                           in its  business,  investors  should  be aware of the
                           possible risks. As is widely known, there is a chance
                           that some  computer  systems may not  function  after
                           December  31,  1999  because  they fail to  recognize
                           dates in the year  2000 and  beyond.  If a system  at
                           INVESCO or one of its business  partners should fail,
                           it could adversely affect the Fund. In addition,  the
                           markets  for, or values of,  securities  in which the
                           Fund invests  could be affected by computer  failures
                           on or after  January 1, 2000.  While  INVESCO  cannot
                           make  assurances  that  this  will  not  happen,   it
                           continues to  thoroughly  analyze the  securities  it
                           invests in,  including  the  possible  effects of the
                           year  2000  computer  problems  on a  company  or the
                           market the security  trades in. See "Risk Factors and
                           Special Considerations - Year 2000."

                           You should carefully  consider your ability to assume
                           the  foregoing  risks before  making an investment in
                           the Fund. An investment in Shares is not  appropriate
                           for all investors.



                                       9
<PAGE>


THE FOLLOWING  FEE TABLE AND THE EXAMPLE BELOW ARE INTENDED TO ASSIST  INVESTORS
IN  UNDERSTANDING  THE  VARIOUS  COSTS AND  EXPENSES  THAT AN  INVESTOR  IN THIS
OFFERING WILL BEAR, DIRECTLY OR INDIRECTLY.

                                    FEE TABLE

SHAREHOLDER TRANSACTION EXPENSES
Sales Load (as a percentage of Subscription Price)(1)......................3.75%
Dividend Reinvestment and Cash Purchase Plan Fees(2)........................None

ANNUAL FUND OPERATING EXPENSES (AS A PERCENTAGE OF NET ASSETS ATTRIBUTABLE TO
SHARES)(3)

Management and Administrative Fees(4)..................................... 0.99%

Interest Payments on Borrowed Funds ........................................None

Other Expenses(5)..........................................................0.27%

Total Annual Fund Expenses.................................................1.31%

- -------------


(1) The Fund has agreed to pay the Dealer  Manager a Dealer  Manager Fee for its
financial  advisory  and  marketing  services  equal to  1.25% of the  aggregate
Subscription Price for each Share issued pursuant to the Offer, and the Fund has
also agreed to pay  broker-dealers,  including the Dealer Manager,  Solicitation
Fees for their solicitation efforts of 2.50% of the Subscription Price per Share
for each Share issued pursuant to the Offer. Other offering expenses incurred by
the Fund are  estimated at $596,200,  which  includes up to $100,000 that may be
paid to the Dealer Manager as partial reimbursement for its expenses relating to
the Offer.  These fees and expenses will be borne by the Fund and  indirectly by
all of the Fund's shareholders, including those shareholders who do not exercise
their Rights.

(2)  Each  participant  in the  Dividend  Reinvestment  and Cash  Purchase  Plan
("Reinvestment  Plan")  will  pay a PRO  RATA  share  of  brokerage  commissions
incurred  in  connection  with   open-market   purchases  of  Shares  under  the
Reinvestment Plan.

(3) Amounts are estimated for the Fund's current fiscal year after giving effect
to  anticipated  Proceeds  of the  Offer,  assuming  that all of the  Rights are
exercised and that the Fund incurs the estimated $596,200 of offering expenses.

(4) The Fund pays an  annualized  management  fee in the  amount of 1.00% on the
first $500  million of the  Fund's  daily net assets and 0.90% on amounts  above
$500 million. The Fund also pays an annualized  administrative fee in the amount
of  0.10%  of the  Fund's  ending  daily  net  assets.  See  "Management  of the
Fund--Investment Management Agreement."

(5) This number includes the expenses of this Rights Offering. Total Annual Fund
Operating Expenses as a percentage of net assets attributable to Shares less the
expenses of this Right Offering would be ___%.



                                       10
<PAGE>

EXAMPLE


The  following  Example  demonstrates  the  projected  dollar  amount  of  total
cumulative expense that would be incurred over various periods with respect to a
hypothetical investment in the Fund through this Offering.

                                1 YEAR      3 YEARS      5 YEARS      10 YEARS

An investor would directly
or indirectly pay the
following expenses on a
$1,000 investment in the
Fund, assuming a 5% annual       $50          $77          $107         $190
return:






The Example set forth above  assumes  reinvestment  of all  dividends  and other
distributions  at NAV, payment of a 3.75% sales load and an annual expense ratio
of 1.31%.  However,  participants  in the  Reinvestment  Plan may receive Shares
purchased of issued at a price or value  different  from NAV. See "Dividends and
Other Distributions; Dividend Reinvestment and Cash Purchase Plan."


THE EXAMPLE SHOULD NOT BE CONSIDERED A REPRESENTATION  OF FUTURE  EXPENSES,  AND
THE FUND'S ACTUAL EXPENSES MAY BE MORE OR LESS THAN THOSE SHOWN.





















                                       11
<PAGE>

                              FINANCIAL HIGHLIGHTS

The table below sets forth certain specified information for a Share outstanding
throughout  each period  presented.  Except for the period from November 1, 1998
through April 30, 1999, the financial  highlights for each period presented have
been audited by PricewaterhouseCoopers  LLP, the Fund's independent accountants,
whose  unqualified  report is  included  in the Fund's  October  31, 1998 Annual
Report and is  incorporated  by reference in the SAI. The  financial  highlights
should be read in  conjunction  with the financial  statements and notes thereto
included  in the Fund's  October  31, 1998  Annual  Report,  which is  available
without charge by calling the Fund at  1-800-528-8765  or by contacting the Fund
at 7800 E. Union Avenue, Suite 800, Denver, Colorado 80237.

<TABLE>
<CAPTION>
<S>                                         <C>                       <C>        <C>       <C>


                                             Six Month Period              Year Ended October 31
                                            Ended April 30, 1999           ---------------------
                                            --------------------
                                                 (unaudited)          1998(f)       1997      1996
                                                 -----------          ----          ----      ----
PER SHARE DATA
Net Asset Value - Beginning of Period                     $21.08      $21.250    $22.230   $18.506
- --------------------------------------------------------------------------------------------------
INCOME FROM INVESTMENT
OPERATIONS

Net Investment Income (Loss)                             (0.015)        0.000    (0.071)   (0.097)

Net Gains or (Losses) on Securities
(Both Realized and Unrealized)                             1.487        3.755      3.564     3.821
- --------------------------------------------------------------------------------------------------
TOTAL FROM INVESTMENT
OPERATIONS                                                 1.472        3.755      3.493     3.724
- --------------------------------------------------------------------------------------------------
LESS DISTRIBUTIONS

Dividends from Net Investment Income                       0.000        0.000      0.000     0.000

Distributions from Net Capital Gains                       3.152        3.925      4.473     0.000
- --------------------------------------------------------------------------------------------------
TOTAL DISTRIBUTIONS                                        3.152        3.925      4.473     0.000
- --------------------------------------------------------------------------------------------------
Net Asset Value - End of Period                          $19.400      $21.080    $21.250   $22.230
- --------------------------------------------------------------------------------------------------
Share Market Price, End of Period                         17.313      $19.500    $17.313   $17.000
- --------------------------------------------------------------------------------------------------
TOTAL RETURN(b)                                         4.73%(c)       40.29%     32.98%    15.25%

RATIOS

Net Assets - End of Period ($000 Omitted)               $585,190     $586,263   $526,215  $455,842

Ratio of Expenses to Average Net Assets                 0.60%(c)     1.21%(d)   1.22%(d)     1.21%

Ratio of Net Investment Income (Loss)
to Average Net Assets                                 (0.08%)(c)      (0.17%)    (0.15%)   (0.44%)

Portfolio Turnover Rate                                   32%(c)          87%       145%       91%

                                                                       FOOTNOTES ON FOLLOWING PAGE
</TABLE>


                                       12
<PAGE>


                                             Year Ended October 31
                                             ---------------------
<TABLE>
<CAPTION>
<S>                                          <C>       <C>       <C>       <C>

                                                                           Period Ended
                                             1995      1994      1993       October 31,
                                             ----      ----      ----      ------------
                                                                                1992(a)
                                                                                ----
PER SHARE DATA

Net Asset Value - Beginning of Period     $12.378   $12.121   $12.643           $13.950
- ---------------------------------------------------------------------------------------
INCOME FROM INVESTMENT
OPERATIONS

Net Investment Income (Loss)              (0.107)   (0.085)     0.205             0.071


Net Gains or (Losses) on Securities
(Both Realized and Unrealized)              6.235     0.542   (0.652)           (1.345)
- ---------------------------------------------------------------------------------------
TOTAL FROM INVESTMENT
OPERATIONS                                  6.128     0.457   (0.447)           (1.274)
- ---------------------------------------------------------------------------------------
LESS DISTRIBUTIONS


Dividends from Net Investment Income        0.000     0.200     0.075             0.000


Distributions from Net Capital Gains        0.000     0.000     0.000             0.033
- ---------------------------------------------------------------------------------------
TOTAL DISTRIBUTIONS                         0.000     0.200     0.075             0.033
- ---------------------------------------------------------------------------------------
Net Asset Value - End of Period           $18.506   $12.378   $12.121           $12.643
- ---------------------------------------------------------------------------------------
Share Price, End of Period                $14.750   $10.000   $11.500           $11.500
- ---------------------------------------------------------------------------------------
TOTAL RETURN(b)                            47.50%  (11.49%)     0.67%       (17.56%)(c)


RATIOS

Net Assets - End of Period
($000 Omitted)                           $379,503  $253,834  $248,564          $259,279


Ratio of Expenses to Average
Net Assets                                  1.33%     1.41%     1.39%          1.35%(e)

Ratio of Net Investment Income
(Loss) to Average Net Assets              (0.72%)   (0.70%)     1.74%          0.72%(e)

Portfolio Turnover Rate                      105%      121%      226%           215%(c)
</TABLE>


(a) From January 24, 1992, commencement of investment operations, to October 31,
1998.

(b) Total  return is  calculated  assuming a purchase  of shares at the  current
market price on the first day and a sale at the current market price on the last
day of each period  reported.  Dividends  and other  distributions,  if any, are
assumed,  for purposes of this calculation,  to be reinvested at prices obtained
under the  Reinvestment  Plan.  Total return does not reflect  sales  charges or
brokerage commissions.

(c)  Based  on  operations  for  the  period  shown  and,  accordingly,  are not
representative of a full year.

(d) Ratio is based on total  expenses  of the Fund,  which is before any expense
offset arrangements.

(e) Annualized

(f) INVESCO has served as the Fund's investment  adviser since February 4, 1998.
Prior to February  4, 1998,  ITC,  then a wholly  owned  subsidiary  of INVESCO,
served as the Fund's investment adviser.


                                       13
<PAGE>

PORTFOLIO CHARACTERISTICS AND COMPOSITION

The  following  tables  set  forth  certain  information  with  respect  to  the
characteristics  and the  composition of the Fund's  investment  portfolio as of
April 30, 1999. Portfolio composition and weightings are subject to change.


PORTFOLIO COMPOSITION--TOP TEN HOLDINGS (unaudited)
DESCRIPTION                                  VALUE         % OF NET ASSETS

Medtronic Inc.                            $49,972,320              8.54%
Merck & Co.                                35,743,200              6.11
Guidant Corp.                              34,711,653              5.93
Johnson & Johnson                          33,364,500              5.70
Warner-Lambert Co.                         31,307,298              5.35
Bristol-Myers Squibb                       30,935,869              5.29
Pharmacia & Upjohn                         28,940,800              4.95
Schering-Plough Corp.                      28,117,875              4.80
Pfizer Inc.                                28,029,225              4.79
Lilly (Eli) & Co.                          26,245,472              4.48

Total                                    $327,368,212             55.94%
COMPOSITION OF HOLDINGS IS SUBJECT TO CHANGE.

PORTFOLIO COMPOSITION - DESCRIPTION OF HOLDINGS


COMMON STOCKS & WARRANTS                      92.61%
BIOTECHNOLOGY                                  6.82%
HEALTH CARE DELIVERY                           0.54%
MEDICAL DEVICES & SUPPLIES                    22.19%
PHARMACEUTICALS                               63.06%

PREFERRED STOCKS                               6.55%
BIOTECHNOLOGY                                  3.10%
HEALTH CARE DELIVERY                           0.68%
MEDICAL DEVICES & SUPPLIES                     2.77%

FIXED INCOME SECURITIES                        0.06%
HEALTH CARE DELIVERY                           0.06%

SHORT-TERM INVESTMENTS                         0.78%
CORPORATE BONDS                                0.78%
BIOTECHNOLOGY                                  0.78%

TOTAL INVESTMENT SECURITIES AT VALUE         100.00%
COMPOSITION OF HOLDINGS IS SUBJECT TO CHANGE.


                                       14
<PAGE>

                        CAPITALIZATION AT APRIL 30, 1999



                                     SHARES OUTSTANDING
                                      EXCLUSIVE OF AMOUNT
                         AMOUNT      HELD BY FUND FOR ITS   AMOUNT HELD BY FUND
   TITLE OF CLASS      AUTHORIZED         OWN ACCOUNT       FOR ITS OWN ACCOUNT
   --------------      ----------         -----------       -------------------
Common Shares of
Beneficial
Interest, par value    Unlimited          30,156,115                -0-
$0.01


                     INFORMATION REGARDING SENIOR SECURITIES

Subject to its investment restrictions,  the Fund has the right to use financial
leverage  to finance  the  repurchase  of or tender  offers for Shares or to pay
dividends and other  distributions  and may borrow for temporary  purposes.  The
Fund  expects it may use  financial  leverage  from time to time in the  future.
Currently,  however,  the  Fund has not  determined  the  timing  or  amount  of
financial leverage that it would utilize.

                     TRADING AND NET ASSET VALUE INFORMATION

In the past, the Shares have generally  traded at a discount in relation to NAV.
Shares of closed-end investment companies, such as the Fund, frequently trade at
a discount from NAV. See "Risk Factors and Special Considerations."

The Shares are listed and traded on the NYSE under the ticker  symbol "GHS." The
Rights will not be admitted for trading on the NYSE or any other stock exchange.
The  average  weekly  trading  volume of the Shares on the NYSE  during the year
ended  December 31, 1998 was 70,680  Shares.  The following  table shows for the
fiscal  quarters for the two most recent  fiscal  years and the fiscal  quarters
during the current fiscal year: (1) the high and low sale price of the Shares on
the NYSE  during  the  quarter;  (2) the high and low NAV per Share  during  the
quarter; and (3) the high and low premium or discount to NAV at which the Shares
were trading during the quarter.



                                                              DISCOUNT TO NET
     For the         NYSE PRICE        NET ASSET VALUE          ASSET VALUE
  Quarter Ended   High     Low        High        Low        High      Low
- --------------------------------------------------------------------------------
January 31, 1997  $18.8750 $14.3750   $22.87      $18.03    (23.677%) (17.360%)
April 30, 1997    $17.3750 $14.5000   $20.36      $17.94    (19.666%) (14.330%)
July 31, 1997     $18.1875 $14.8750   $21.87      $18.48    (21.411%) (14.907%)
October 31, 1997  $18.6250 $16.2500   $22.87      $20.39    (21.053%) (16.027%)
January 31, 1998  $18.750  $15.9375   $21.99      $17.88    (18.137%) (7.771%)
April 30, 1998    $19.8750 $18.0000   $21.82      $20.09    (13.338%) (6.064%)
July 31, 1998     $21.0625 $18.5000   $22.71      $20.15    (10.755%) (5.938%)
October 31, 1998  $19.5000 $15.7500   $21.35      $18.74    (16.578%) (7.495%)
January 31, 1999  $20.0625 $17.6875   $21.68      $18.77    (9.199%)  (2.927%)
April 30, 1999    $19.875  $17.25     $21.29      $18.79    (14.342%) (3.582%)
- --------------------------------------------------------------------------------


                                       15
<PAGE>


The NAV per Share at the close of business on April 6, 1999,  (the last  trading
date on which the Fund publicly  reported its NAV prior to the  announcement  of
the Offer) and on May 21, 1999, (the last trading date prior to the date of this
Prospectus  on which the Fund  publicly  reported its NAV per Share) were $20.60
and $18.63,  respectively,  and the last reported sales prices of a Share on the
NYSE on those dates were $18.94 and $16.69, respectively.  See "Net Asset Value"
in the SAI.


                                    THE FUND

The Fund is a diversified  closed-end  investment  management company registered
with the SEC. It is actively managed to seek capital appreciation.  Employing an
aggressive investment philosophy,  the Fund normally invests at least 80% of its
total  assets in equity  securities  of Health  Science  Companies.  There is no
guarantee  that the Fund will meet its  investment  objective.  See  "Investment
Objective and Policies" and "Risk Factors and Special Considerations."

The Fund's objective is to seek capital appreciation by investing  substantially
all of its assets in equity and related  securities  of U.S. and foreign  Health
Science Companies.  It seeks to achieve its objective by investing its assets in
a  broad  range  of  health  care  related  equities,   such  as  market-leading
pharmaceutical  companies,  medical  devices  manufacturers  and suppliers,  and
various  private  placement  investments.  The Fund may focus its investments in
these  sectors.  For  example,  at this  time  approximately  60% of the  Fund's
portfolio  is  invested  in stocks  of  pharmaceutical  companies.  The Fund may
purchase and sell  options on equities.  For  information  regarding  the Fund's
portfolio  characteristics  and composition as of April 30, 1999, see "Portfolio
Characteristics and Composition."

The  Investment   Manager   believes  that  there  are   attractive   investment
opportunities  available  to the Fund in the  health  sciences  industries.  The
statements  below  relating to  demographics,  research and  development  of new
products, technological developments and economic outlook reflect the beliefs of
the Investment Manager and are based upon publicly available information.

Demographics  continue to indicate  growth in the health sciences  industry,  as
peoples' lives are extended.  The larger  proportion of our  population  over 65
years of age comprises a larger  proportion of our population  than ever before.
This  growing  population  segment  consumes  the largest  percentage  of health
sciences  products,  such as  pharmaceuticals.  In the United States, as persons
born in the late 1940's to early 1950's, known in the United States as the "baby
boomers,"  advance  in age,  they are likely to  consume  increasing  amounts of
chronic care drugs and other health science products.

The health sciences industry has increased research and development expenditures
to  develop  new  and  better   products.   Because  the  U.S.   Food  and  Drug
Administration in the 1900's has continued to expedite approval of new products,
newly-developed  health  products  reach  the  market  at an  accelerated  pace.
Simultaneously,  many Health  Science  Companies  face  relative low exposure to
patent litigation.  With more new products, a shorter  product-to-market period,
and reduced patent  litigation  risk, the health sciences  industry  anticipates
increased revenues and profitability.

The introduction of new technologies in the medical  equipment and biotechnology
sectors  has  contributed  significantly  to growth in the  hospital  supply and
medical  device   industries.   New  technologies  have  enabled  the  increased
development of sophisticated devices and procedures. In addition,  biotechnology
companies  are  offering  an  increasing  number  of  new  products.  Trends  in
demographics  and  potentially   accelerated  drug  approvals  could  result  in
significant growth in the pharmaceutical sector as well. Moreover, the favorable
outlook for the United States economy could benefit the health sciences industry
through more readily available capital for developing  proprietary  products and
by the increasing affluence of consumers of those products.

Closed-end funds, such as the Fund, differ from open-end  management  investment
companies  (commonly  referred to as "mutual  funds") in that  closed-end  funds
generally  list their  shares for trading on a  securities  exchange  and do not
redeem  their shares at the option of the  shareholder.  By  comparison,  mutual


                                       16
<PAGE>

funds issue  securities  redeemable at NAV at the option of the  shareholder and
typically  engage in a  continuous  offering of their  shares.  Mutual funds are
subject to continuous asset in-flows and out-flows that can complicate portfolio
management,  whereas  closed-end funds generally can stay more fully invested in
securities  consistent with their respective investment objectives and policies.
In addition,  in comparison  to open-end  funds,  closed-end  funds have greater
flexibility in the  employment of financial  leverage and in the ability to make
certain  types of  investments,  such as  investments  in  illiquid  securities.
However,  shares of closed-end  funds  frequently trade at a discount from their
NAV.


The Fund was organized as a business trust under the laws of the Commonwealth of
Massachusetts  on November  18, 1991 and has  registered  with the SEC under the
1940 Act. The Fund commenced investment operations on January 24, 1992 under the
name Global Health  Sciences  Fund. On April 30, 1997,  the name of the Fund was
changed to INVESCO Global Health Sciences Fund. The Fund's  principal  office is
located at 7800 E. Union Avenue, Suite 800, Denver, Colorado 80237. The Fund has
contracted  with  INVESCO  to serve as its  investment  adviser.  INVESCO  is an
investment management firm registered with the SEC under the Investment Advisers
Act of 1940, as amended.


                                    THE OFFER

PURPOSE OF THE OFFER


As discussed below, the Board of Trustees has determined that it would be in the
best  interests of the Fund and its  shareholders  to make the Offer.  The Board
considered the proposal for the Offer at several  meetings,  including a meeting
at which the independent  Trustees (as defined under the 1940 Act) ("Independent
Trustees") met with counsel and without management present to discuss the Offer.
The Board,  including all of the Independent Trustees,  unanimously approved the
Offer.  In its  deliberations,  the Board  considered  a number  of  issues  and
factors,  including the potential impact of the Offer on current  exercising and
non-exercising  shareholders;  the  potential  impact of the Offer on the Fund's
NAV, Share price,  present and potential  discount to NAV, and trading activity;
the potential  dilutive impact of the Offer on the Fund and its shareholders (in
particular non-exercising shareholders);  the revenue impact of the Offer on the
Investment  Manager and its  affiliates;  the value and quality of the  services
expected  to be  provided  by the Dealer  Manager  in light of the  relationship
between  the Dealer  Manager and  existing  shareholders;  the Dealer  Manager's
familiarity with the Fund and with the Investment Manager;  and the terms of the
Offer  compared to the terms of similar  offers  conducted  by other  closed-end
funds.  The Board of Trustees  concluded that  increasing the assets of the Fund
would be beneficial to the Fund and its shareholders.  However,  there can be no
assurance that any of the anticipated benefits discussed in this Prospectus will
be realized as a result of the Offer.


The Board  determined that it would be in the best interests of the Fund and its
existing  shareholders  to  increase  the  assets  of  the  Fund  available  for
investment,  thereby allowing the Fund more fully to take advantage of available
investment  opportunities  consistent with its investment objective. In reaching
its decision,  the Board of Trustees was advised by the Investment  Manager that
the  availability  of new  assets  would  give  the Fund  additional  investment
flexibility,  as well as an  enhanced  ability  to take  advantage  of what  the
Investment Manager believes to be timely investment opportunities.  It was noted
that,  to take  advantage  of these  opportunities  without an  infusion  of new
capital, the Fund would be required to sell current portfolio positions that the
Investment  Manager  believes  the Fund  should  retain,  which  could cause the
realization of significant  capital gains by the Fund and its shareholders.  The
Investment  Manager  provided  its views to the effect that while the Fund could
seek to obtain  shareholder  approval to borrow  money for  investment  purposes
under  current  market  conditions,  it would not be prudent  to do so,  because
raising  additional  money through the Offer would be less costly than borrowing
the same amount of money. With an increased asset base as a result of the Offer,

                                       17
<PAGE>

the  Investment  Manager  believes  the Fund would be able to invest in a larger
universe of securities that it believes would have the benefits described below.

The  Board  of  Trustees  considered  that the Fund  potentially  could  achieve
additional  economies  of scale  as a result  of an  increase  in total  assets,
resulting  in a nominal  decrease  in the Fund's  operating  expense  ratio.  In
addition,  the  Fund  and  the  Investment  Manager  recently  agreed  to  add a
breakpoint to the investment  management  agreement for assets in excess of $500
million. At the Fund's current asset size,  substantially all of the Proceeds of
the Offer  would be managed at this  lower fee,  which  could have the effect of
lowering the Fund's overall  expense ratio.  In addition,  the Board of Trustees
considered  that the  Offering  could  ultimately  result in a larger  number of
shareholders  and  daily  trading  volume  and  therefore  could  result  in  an
improvement  in the liquidity of the trading  market for the Shares on the NYSE,
where the Shares are listed and traded. The Board of Trustees also believes that
a larger number of outstanding  Shares and a larger number of beneficial  owners
of Shares could increase the level of market interest in the Fund.

In addition,  the Board of Trustees  considered that the Offer affords  existing
shareholders the opportunity to purchase  additional Shares at a price that will
be below the lower of market value or NAV. The Board of Trustees also considered
the  expenses  of the Offer and its  dilutive  effect,  including  the effect on
non-exercising shareholders. The Board, however, cannot determine precisely what
the extent of the dilution might be until the completion of the Offer.


The Board of Trustees  noted that the  Investment  Manager will benefit from the
Offer  because  its fees for  investment  management  services  are based on the
average daily net assets of the Fund. It is not possible to state  precisely the
amount of  additional  compensation  the  Investment  Manager  will receive as a
result of the Offer,  because it is not known how many Rights will be  exercised
and because the Proceeds of the Offer will be invested in  additional  portfolio
securities that may fluctuate in value. However, if all the Rights are exercised
in full,  including  the  additional  1,520,306  Shares  by  which  the Fund may
increase  the  Offer,  based  on the  Estimated  Subscription  Price  of $ , the
Investment  Manager  would receive  additional  fees for  investment  management
services of  approximately  $ per annum and additional  fees for  administrative
services of  approximately  $___ per annum as a result of the increase in assets
under management.


In  determining  that the  Offer is in the  best  interests  of the Fund and its
shareholders,  the Board of Trustees  retained the Dealer Manager to provide the
Fund with  financial  advisory  and  marketing  services  relating to the Offer,
including  the  structure,  timing and terms of the Offer.  In  addition  to the
foregoing,  the  Board of  Trustees  considered,  among  other  things,  using a
variable pricing versus fixed pricing  mechanism,  the benefits and drawbacks of
conducting a non-transferable  versus a transferable rights offering, the effect
on the Fund if the Offer is  undersubscribed  and the  experience  of the Dealer
Manager in conducting rights offerings. The Investment Manager advised the Board
that the  non-transferability  of the Rights may limit,  but will not eliminate,
the activity of arbitrageurs.


The Fund and the  Investment  Manager  have  received an order and an  amendment
thereto  (collectively  "Order") from the SEC  permitting the Fund to make up to
four  distributions of net long-term  capital gains in any taxable year, so long
as the Fund  maintains in effect a  distribution  policy  calling for  quarterly
distributions  of a fixed  percentage  of its NAV (the  "Quarterly  Distribution
Policy").  The Fund and the  Investment  Manager  agreed that, as a condition to
obtaining the Order,  the relief  granted by the Order shall  terminate upon the
effective date of a registration  statement under the Securities Act of 1933 for
any  future  public  offering  by the  Fund of  Shares.  The  Order  will not be
terminated,  however,  for (among other specified  reasons) a rights offering to
shareholders  of the Fund if (a) Shares will be issued only within the  six-week
period immediately  following the record date of a quarterly  dividend,  (b) the
prospectus for such rights offering makes it clear that shareholders  exercising


                                       18
<PAGE>

the Rights will not be entitled to receive such  dividend,  and (c) the Fund has
not engaged in more than one rights  offering  during any given  calendar  year.
Final  settlement  will occur and Shares will be delivered  on or about July 12,
1999.


The Fund may,  in the future and at its  discretion,  choose to make  additional
rights offerings of Shares from time to time for a number of Shares and on terms
that may or may not be similar to this Offer.  Any such future  offering will be
made in accordance with the 1940 Act.

TERMS OF THE OFFER


The  Fund  is  issuing  to  Record  Date  Shareholders  non-transferable  Rights
entitling the holders thereof to subscribe for an aggregate of 6,081,223 Shares,
par value $0.01 per Share (7,601,529  Shares if the Fund increases the number of
Shares available by up to 25% in connection with the Over-Subscription Privilege
described  below).  Each Record Date  Shareholder  is being issued one Right for
every five Shares  owned on the Record Date  (1-for-5).  The Rights  entitle the
holders  thereof  to  subscribe  for one Share  for  every  one Right  held (the
"Primary Subscription"). Fractional Shares will not be issued on the exercise of
fractional  Rights.  Accordingly,   Shares  may  be  purchased  in  the  Primary
Subscription  only pursuant to the exercise of whole Rights.  For example,  if a
Record Date  Shareholder  owns 102 Shares,  that  shareholder  will receive 20.4
Rights, but may only exercise 20 Rights for the purchase of 20 Shares,  with the
unexercised  fractional  Rights  expiring.  However,  Record  Date  Shareholders
holding  fewer than five Shares will be entitled to one Right to  subscribe  for
one Share pursuant to the Primary  Subscription.  Record Date  Shareholders  may
request additional Shares pursuant to the Over-Subscription  Privilege described
below.

Rights may be  exercised  at any time  during  the  subscription  period,  which
commences on May 25, 1999 and ends at 5:00 P.M., Eastern time, on the Expiration
Date (the "Subscription Period"). See "Expiration Date of the Offer." The Rights
are evidenced by  Subscription  Certificates  that will be mailed to Record Date
Shareholders, except as discussed below under "Foreign Restrictions."

Shares not subscribed for in the Primary  Subscription will be offered, by means
of the Over-Subscription  Privilege,  to those Record Date Shareholders who have
exercised all Rights issued to them and who wish to acquire more than the number
of whole Shares they are entitled to purchase  pursuant to the exercise of their
Rights  in  the  Primary   Subscription.   Shares   acquired   pursuant  to  the
Over-Subscription  Privilege  are  subject  to  allotment  and may be subject to
increase, as more fully discussed below under "Over-Subscription Privilege." For
purposes of determining  the maximum number of Shares a Record Date  Shareholder
may acquire  pursuant to the Offer,  Record Date  Shareholders  whose Shares are
held of record by Cede & Co.  ("Cede"),  as  nominee  for The  Depository  Trust
Company ("DTC"), or by any other depository or nominee, will be deemed to be the
holders  of the  Rights  that are  issued to Cede or such  other  depository  or
nominee on their behalf.


Because  fractional  Shares  will not be issued,  Record Date  Shareholders  who
receive or have  remaining  fractional  Rights will be unable to  exercise  such
remaining Rights for the purchase of fractional  Shares and will not be entitled
to receive any cash in lieu thereof.  Such shareholders  may,  however,  request
additional Shares pursuant to the Over-Subscription Privilege.


The  Board of  Trustees,  in  consultation  with  the  Investment  Manager,  has
implemented a Quarterly Distribution Policy, which entails quarterly payments of
dividends in an amount equal to 2.5% of the Fund's NAV. The first dividend to be
paid on Shares  acquired on  exercise of the Rights will be the first  quarterly


                                       19
<PAGE>

dividend,  the record date for which  occurs  after the  issuance of the Shares.
Assuming the Subscription Period is not extended,  it is expected that the first
dividend received by shareholders  acquiring Shares in the Offer will be paid on
August 24, 1999 (payable date).


There is no minimum  number of Rights  that must be  exercised  in order for the
Offer to close.

The record date for the Fund's most recent quarterly  dividend was May 11, 1999.
Record Date  Shareholders  will not be entitled to receive  that  dividend  with
respect to those Shares that they receive pursuant to the Offer.

OVER-SUBSCRIPTION PRIVILEGE


If Record Date  Shareholders  do not exercise all the Rights issued to them, any
Shares  represented  by  unexercised  Rights  will be  offered  by  means of the
Over-Subscription  Privilege to the Record Date  Shareholders who have exercised
all the Rights issued to them and who wish to subscribe for  additional  Shares.
Only Record Date  Shareholders  who exercise  all the Rights  issued to them may
indicate on the  Subscription  Certificate,  which they or their nominees submit
with respect to the exercise of the Rights issued to them,  how many Shares they
desire to purchase pursuant to the  Over-Subscription  Privilege.  If sufficient
Shares   remain   after   completion   of   the   Primary   Subscription,    all
over-subscription requests will be honored in full. If sufficient Shares are not
available   after   completion  of  the  Primary   Subscription   to  honor  all
over-subscription  requests,  the Fund may,  at the  discretion  of the Board of
Trustees,  issue up to an additional 25% of the Shares available pursuant to the
Offer  (up  to  an  additional   1,520,306   Shares)  in  order  to  cover  such
over-subscription   requests.   Regardless  of  whether  the  Fund  issues  such
additional  Shares,  and to the  extent  Shares are not  available  to honor all
over-subscription  requests,  the available Shares will be allocated among those
who over-subscribe so that the number of Shares issued to such shareholders will
generally be in proportion to the number of Shares owned by such shareholders on
the Record Date. The  allocation  process may involve a series of allocations in
order to assure that the total number of Shares available for  over-subscription
is distributed on a PRO RATA basis.

Banks, brokers, trustees and other nominee holders of Rights will be required to
certify   to  the   Subscription   Agent  (as   defined   below),   before   any
Over-Subscription  Privilege  may be exercised  with  respect to any  particular
beneficial owner, as to the aggregate number of Rights exercised pursuant to the
Primary  Subscription  and the number of Shares  subscribed  for pursuant to the
Over-Subscription  Privilege by such  beneficial  owner and that such beneficial
owner's   Primary   Subscription   was   exercised  in  full.   Nominee   Holder
Over-Subscription  Forms will be  distributed  to banks,  brokers,  trustees and
other nominee holders of Rights with the Subscription Certificates.


The Fund will not offer or sell in connection with the Offer any Shares that are
not subscribed for pursuant to the Primary Subscription or the Over-Subscription
Privilege.


                                       20
<PAGE>

SUBSCRIPTION PRICE


The Subscription Price for each Share to be issued pursuant to the Offer will be
95% of the lower of (1) the average of the last  reported  sales price per Share
on the NYSE on the  Expiration  Date and on the preceding  four Business Days or
(2) the  closing  NAV per Share on the  Expiration  Date.  For  example,  if the
average of the last reported sales price per Share on the NYSE on the Expiration
Date and on the four preceding  Business Days is $20.00, and the closing NAV per
Share on the Expiration Date is $19.00,  the  Subscription  Price will be $18.05
(95% of $19.00).  If, however,  the average of the last reported sales price per
Share on the NYSE on the Expiration Date and on the four preceding Business Days
is $18.00,  and the closing NAV per Share on the Expiration Date is $19.00,  the
Subscription Price will be $17.10 (95% of $18.00).

The Fund announced the Offer on April 7, 1999. The NAV per Share at the close of
business  on April 6,  1999 (the last  trading  date on which the Fund  publicly
reported its NAV per Share prior to the  announcement)  and on May 21, 1999 (the
last trading date on which the Fund publicly reported its NAV per Share prior to
the date of this Prospectus) was $20.60 and $18.63,  respectively,  and the last
reported  sale  price  per  Share on the NYSE on those  dates  was $18 15/16 and
$16.69, respectively.


NON-TRANSFERABILITY OF RIGHTS

The Rights are  non-transferable  and, therefore,  may not be purchased or sold.
The Rights  will not be listed for  trading on the NYSE or any other  securities
exchange.  However, the Shares to be issued pursuant to the Offer will be listed
for trading on the NYSE, subject to notice of issuance.


EXPIRATION DATE OF THE OFFER

The Offer will  expire at 5:00 P.M.,  Eastern  time,  on June 18,  1999,  unless
extended  by the Fund until 5:00 P.M.,  Eastern  time,  to a date not later than
June 21, 1999. The Rights will expire on the Expiration  Date and thereafter may
not be exercised. Because the Offer expires and the Shares will be priced on the
same date,  Record Date Shareholders who decide to acquire Shares in the Primary
Subscription  or pursuant to the  Over-Subscription  Privilege will not know the
Subscription Price of the Shares when they make their decision. Any extension of
the Offer will be followed as promptly as practicable by  announcement  thereof.
Such announcement  will be issued no later than 9:00 A.M.,  Eastern time, on the
next Business Day following the previously  scheduled  Expiration Date.  Without
limiting the manner in which the Fund may choose to make such announcement,  the
Fund will not, unless otherwise required by law, have any obligation to publish,
advertise or otherwise  communicate any such announcement other than by making a
release to the Dow Jones News Service or such other means of announcement as the
Fund deems appropriate.


SUBSCRIPTION AGENT


The subscription agent is EquiServe, Inc. (the "Subscription Agent" or "EI"). EI
will receive for its administrative, processing, invoicing and other services as
Subscription Agent, a fee estimated to be approximately  $70,334, which includes
reimbursement  for  all  out-of-pocket   expenses  related  to  the  Offer.  The
Subscription Agent is also the Fund's transfer agent,  dividend-paying agent and
registrar  for the Shares.  Questions  regarding the  Subscription  Certificates
should be directed to Shareholder  Communications  Corporation at 1-800-722-4072
(toll free);  shareholders may also consult their brokers or nominees. Banks and
broker-dealers   should  contact  Shareholder   Communications   Corporation  at
1-212-805-7113.



                                       21
<PAGE>

Completed Subscription Certificates must be sent together with proper payment of
the Subscription Price for all Shares subscribed for in the Primary Subscription
and pursuant to the  Over-Subscription  Privilege (for Record Date Shareholders)
to EI by one of the methods described below.


Alternatively, a Notice of Guaranteed Delivery may be sent by facsimile to (781)
575-4826 to be received by the  Subscription  Agent prior to 5:00 P.M.,  Eastern
time, on the  Expiration  Date.  Facsimiles  should be confirmed by telephone at
(781)  575-4816.  The Fund will  accept only  properly  completed  and  executed
Subscription  Certificates  actually  received  at any of the  addresses  listed
below,  prior to 5:00 P.M., Eastern time, on the Expiration Date or by the close
of business on the third Business Day after the Expiration Date following timely
receipt of a Notice of Guaranteed Delivery. See "Payment for Shares" below.



BY FIRST CLASS MAIL:      BY OVERNIGHT COURIER:      BY HAND:
EQUISERVE, INC.           EQUISERVE, INC.            EQUISERVE, INC.
c/o State Street Bank     c/o State Street Bank      Securities Transfer and
 and Trust Company         and Trust Company          Reporting Services, Inc.
Corporate Actions         Corporate Actions          100 William Street Galleria
P.O. Box 9573             40 Campanelli Drive        New York, NY 10038
Boston, MA 02205-9573     Braintree, MA 02184        U.S.A.
U.S.A.                    U.S.A.


             DELIVERY TO AN ADDRESS OTHER THAN ONE OF THE ADDRESSES
                LISTED ABOVE WILL NOT CONSTITUTE VALID DELIVERY.

METHOD FOR EXERCISING RIGHTS


Rights are  evidenced by  Subscription  Certificates  that,  except as described
below under "Foreign  Restrictions,"  will be mailed to Record Date Shareholders
or,  if a  shareholder's  Shares  are held by Cede or any  other  depository  or
nominee on their behalf,  to Cede or such  depository or nominee.  Rights may be
exercised  by  completing  and  signing  the   Subscription   Certificate   that
accompanies  this  Prospectus  and  mailing  it in  the  envelope  provided,  or
otherwise  delivering the completed and signed  Subscription  Certificate to the
Subscription  Agent,  together  with  payment  in  full  for the  Shares  at the
Estimated  Subscription  Price  by the  Expiration  Date.  Rights  may  also  be
exercised by contacting your broker, banker or trust company, which can arrange,
on your behalf,  to guarantee  payment and delivery of a properly  completed and
executed Subscription Certificate pursuant to a Notice of Guaranteed Delivery by
the close of business on the third Business Day after the Expiration Date. A fee
may be charged for this service.  Because  fractional Shares will not be issued,
Record Date Shareholders who receive or have remaining fractional Rights will be
unable to purchase  fractional  Shares on the exercise of such remaining  Rights
and will not be entitled to receive any cash in lieu thereof.  For example, if a
Record Date  Shareholder  owns 102 Shares,  that  shareholder  will receive 20.4
Rights, but may only exercise 20 Rights for the purchase of 20 Shares,  with the
unexercised  fractional  Rights  expiring.  However,  Record  Date  Shareholders
holding  fewer than five Shares will be entitled to one Right to  subscribe  for
one Share pursuant to the Primary  Subscription.  Record Date  Shareholders  who
exercise  all their  Rights  pursuant  to the Primary  Subscription  may request
additional  Shares  pursuant  to  the  Over-Subscription  Privilege.   Completed
Subscription  Certificates  must be received by the Subscription  Agent prior to
5:00 P.M.,  Eastern  time,  on the  Expiration  Date at one of the addresses set
forth above  (unless the  guaranteed  delivery  procedures  are complied with as
described below under "Payment for Shares").


SHAREHOLDERS  WHO ARE RECORD  OWNERS.  To  exercise  their  Rights,  Record Date
Shareholders may choose between either option to exercise their Rights set forth

                                       22
<PAGE>

under  "Payment for Shares" below.  If time is of the essence,  option (2) under
"Payment for Shares" below will permit delivery of the Subscription  Certificate
and payment after the Expiration Date.

SHAREHOLDERS  WHOSE SHARES ARE HELD BY A NOMINEE.  Shareholders whose Shares are
held by a nominee such as a bank, broker or trustee must contact that nominee to
exercise their Rights.  In that case, the nominee will complete the Subscription
Certificate on behalf of the  shareholder  and arrange for proper payment by one
of the methods set forth under "Payment for Shares" below.

NOMINEES.  Nominees who hold Shares for the account of others  should notify the
respective  beneficial  owners of such Shares as soon as  possible to  ascertain
such beneficial  owners'  intentions and to obtain  instructions with respect to
the Rights.  If the beneficial  owner so instructs,  the nominee should complete
the Subscription  Certificate and submit it to the  Subscription  Agent with the
proper payment as described under "Payment for Shares" below.

Trustees of the Fund who own Shares through their deferred fee arrangement  will
receive Rights and may  participate in the Offering.  Further  information  with
respect to the deferred  fee  arrangement  may be obtained  from the Fund or the
Investment Manager.

INFORMATION AGENT

Any questions or requests for  assistance  concerning  the method of subscribing
for  Shares  or  for  additional  copies  of  this  Prospectus  or  Subscription
Certificates  or  Notices  of  Guaranteed   Delivery  may  be  directed  to  the
Information Agent at its telephone number and address listed below:


                     Shareholder Communications Corporation
                                 17 State Street
                               New York, NY 10004
                                 1-800-722-4072
                  Brokers and banks, please call 212-805-7113.

Record  Date  Shareholders  may also  contact  their  brokers  or  nominees  for
information with respect to the Offer. The Information  Agent will receive a fee
estimated to be $63,639,  which  includes  reimbursement  for its  out-of-pocket
expenses related to the Offer.


PAYMENT FOR SHARES

Shareholders who wish to acquire Shares in the Primary Subscription and pursuant
to the  Over-Subscription  Privilege may choose between the following methods of
payment:


   (1) A shareholder may send the Subscription Certificate together with payment
   for the Shares acquired in the Primary Subscription and any additional Shares
   requested to be subscribed for pursuant to the Over-Subscription Privilege to
   the  Subscription  Agent.  Payment  should be  calculated on the basis of the
   Estimated  Subscription Price of [ ] per Share for all Shares  subscribed.  A
   subscription  will  be  accepted  when  payment,  together  with  a  properly
   completed  and  executed  Subscription   Certificate,   is  received  by  the
   Subscription  Agent's office at one of the addresses set forth above no later
   than 5:00 P.M.,  Eastern time, on the Expiration Date. The Subscription Agent
   will deposit all checks and money  orders  received by it for the purchase of
   Shares into a segregated  interest-bearing  account (the  interest from which
   will inure to the benefit of the Fund) pending  proration and distribution of
   Shares.  A PAYMENT  PURSUANT TO THIS METHOD MUST BE IN U.S.  DOLLARS BY MONEY


                                       23
<PAGE>

   ORDER OR CHECK DRAWN ON A BANK OR BRANCH LOCATED IN THE UNITED  STATES,  MUST
   BE PAYABLE TO "INVESCO  GLOBAL  HEALTH  SCIENCES  FUND" AND MUST  ACCOMPANY A
   PROPERLY COMPLETED AND EXECUTED SUBSCRIPTION  CERTIFICATE FOR SUCH PAYMENT TO
   BE  ACCEPTED.  EXERCISE  BY THIS  METHOD IS SUBJECT TO ACTUAL  COLLECTION  OF
   CHECKS  BY  5:00  P.M.,   EASTERN  TIME,  ON  THE  EXPIRATION  DATE.  BECAUSE
   UNCERTIFIED  PERSONAL  CHECKS MAY TAKE AT LEAST FIVE  BUSINESS DAYS TO CLEAR,
   SHAREHOLDERS ARE STRONGLY URGED TO PAY, OR ARRANGE FOR PAYMENT, BY MEANS OF A
   CERTIFIED OR CASHIER'S CHECK OR MONEY ORDER.

   (2) Alternatively, a bank, a trust company or a NYSE member subscription will
   be accepted by the Subscription  Agent if, prior to 5:00 P.M.,  Eastern time,
   on the  Expiration  Date,  the  Subscription  Agent has  received a Notice of
   Guaranteed Delivery by facsimile or otherwise from a bank, a trust company or
   a NYSE  member,  guaranteeing  delivery  of  (i)  payment  of  the  Estimated
   Subscription  Price of [$ ] per Share for the  Shares  subscribed  for in the
   Primary  Subscription  and any additional  Shares  requested  pursuant to the
   Over-Subscription  Privilege,  and (ii) a  properly  completed  and  executed
   Subscription  Certificate.  The Subscription Agent will not honor a Notice of
   Guaranteed  Delivery  unless a properly  completed and executed  Subscription
   Certificate  and full payment for the Shares is received by the  Subscription
   Agent by the close of business on the third Business Day after the Expiration
   Date (June 23, 1999, unless the Offer is extended (the "Protect Period")).



Within five  Business  Days after the end of the Protect  Period (June 30, 1999,
unless the Offer is extended) (the "Confirmation  Date"), a confirmation will be
sent by the  Subscription  Agent to each  subscribing  shareholder  (or,  if the
shareholder's Shares are held by Cede or any other depository or nominee on such
shareholder's  behalf,  to Cede or such depository or nominee),  showing (i) the
number  of Shares  acquired  in the  Primary  Subscription,  (ii) the  number of
Shares, if any, acquired pursuant to the Over-Subscription  Privilege, (iii) the
Subscription  Price per Share and total purchase  price of the Shares,  and (iv)
any additional  amount payable by such  shareholder to the Fund or any excess to
be  refunded  by the  Fund  to  such  shareholder,  in each  case  based  on the
Subscription  Price.  If any  shareholder  exercises his or her Right to acquire
Shares pursuant to the Over-Subscription Privilege, any such excess payment that
would  otherwise  be  refunded  to the  shareholder  will be applied by the Fund
toward   payment  for  Shares   acquired   pursuant  to  the   exercise  of  the
Over-Subscription  Privilege. Any additional payment required from a shareholder
must be received by the Subscription Agent within eighth Business Days after the
Confirmation  Date (July 12,  1999,  unless the Offer is  extended).  Any excess
payment  to be  refunded  by the Fund to a  shareholder  will be  mailed  by the
Subscription Agent to such shareholder as promptly as possible.  All payments by
a shareholder must be in U.S. dollars by money order or check drawn on a bank or
branch  located in the United  States and  payable  to  "INVESCO  GLOBAL  HEALTH
SCIENCES FUND."


The Subscription Agent will deposit all checks received by it prior to the final
payment date into a segregated  interest-bearing  account  (which  interest will
inure to the benefit of the Fund)  pending  proration  and  distribution  of the
Shares.

Whichever of the two methods  described above is used,  issuance and delivery of
certificates  for the Shares  purchased  are subject to collection of checks and
actual payment pursuant to any Notice of Guaranteed Delivery.





If a shareholder who acquires Shares pursuant to the Primary Subscription or the
Over-Subscription  Privilege does not make payment of any additional amounts due
by the tenth  Business Day after the  Confirmation  Date,  the Fund reserves the
right to take any or all of the following actions:  (i) sell such subscribed and


                                       24
<PAGE>

unpaid-for  Shares to other  Record  Date  Shareholders,  (ii) apply any payment
actually  received  toward the purchase of the  greatest  whole number of Shares
that could be  acquired  by such  shareholder  upon the  exercise of the Primary
Subscription and/or Over-Subscription  Privilege,  and/or (iii) exercise any and
all other rights or remedies to which the Fund may be entitled.


THE METHOD OF DELIVERY TO THE FUND OF SUBSCRIPTION  CERTIFICATES  AND PAYMENT OF
THE SUBSCRIPTION PRICE WILL BE AT THE ELECTION AND RISK OF THE EXERCISING RIGHTS
HOLDERS,  BUT IF SENT  BY MAIL IT IS  RECOMMENDED  THAT  SUCH  CERTIFICATES  AND
PAYMENTS BE SENT BY  REGISTERED  MAIL,  PROPERLY  INSURED,  WITH RETURN  RECEIPT
REQUESTED, AND THAT A SUFFICIENT NUMBER OF DAYS BE ALLOWED TO ENSURE DELIVERY TO
THE  SUBSCRIPTION  AGENT AND  CLEARANCE OF PAYMENT  PRIOR TO 5:00 P.M.,  EASTERN
TIME, ON THE EXPIRATION DATE.  BECAUSE  UNCERTIFIED  PERSONAL CHECKS MAY TAKE AT
LEAST FIVE BUSINESS DAYS TO CLEAR, YOU ARE STRONGLY URGED TO PAY, OR ARRANGE FOR
PAYMENT, BY MEANS OF CERTIFIED OR CASHIER'S CHECK OR MONEY ORDER.

All questions concerning the timeliness,  validity,  form and eligibility of any
exercise of Rights will be determined by the Fund, whose  determinations will be
final and  binding.  The Fund in its sole  discretion  may  waive any  defect or
irregularity,  or permit a defect or  irregularity  to be corrected  within such
time as it may  determine,  or  reject  the  purported  exercise  of any  Right.
Subscriptions  will not be deemed to have been  received or  accepted  until all
irregularities  have been waived or cured  within such time as the  Subscription
Agent  determines in its sole  discretion.  The  Subscription  Agent will not be
under any duty to give  notification of any defect or irregularity in connection
with the  submission  of  Subscription  Certificates  or incur any liability for
failure to give such notification.

EXERCISING RIGHTS HOLDERS WILL HAVE NO RIGHT TO RESCIND THEIR SUBSCRIPTION AFTER
RECEIPT  OF THEIR  PAYMENT  FOR  SHARES  BY THE  SUBSCRIPTION  AGENT,  EXCEPT AS
PROVIDED BELOW UNDER "NOTICE OF NET ASSET VALUE DECLINE."

DELIVERY OF SHARE CERTIFICATES

Certificates  representing  Shares acquired in the Primary  Subscription will be
mailed  promptly  after the  expiration  of the Offer once full payment for such
Shares has been received and cleared.  Certificates representing Shares acquired
pursuant  to  the  Over-Subscription   Privilege  will  be  mailed  as  soon  as
practicable after full payment for such Shares has been received and cleared and
all allocations have been completed.  Participants in the Reinvestment Plan will
have any  Shares  acquired  in the  Primary  Subscription  and  pursuant  to the
Over-Subscription  Privilege  credited to their accounts under the  Reinvestment
Plan.  Participants in the  Reinvestment  Plan wishing to exercise Rights issued
with respect to the Shares held in their  accounts under the  Reinvestment  Plan
must  exercise such Rights in accordance  with the  procedures  set forth above.
Shareholders  whose Shares are held of record by Cede or by any other depository
or nominee on their behalf or their broker-dealer's  behalf will have any Shares
acquired  in the  Primary  Subscription  credited to the account of Cede or such
other depository or nominee.  Shares acquired pursuant to the  Over-Subscription
Privilege will be certificated,  and certificates  representing such Shares will
be sent directly to Cede or such other depository or nominee. Share certificates
will not be issued for Shares credited to Reinvestment Plan accounts.

FOREIGN RESTRICTIONS

Subscription  Certificates will not be mailed to Record Date Shareholders  whose
record addresses are outside the United States. Foreign Record Date Shareholders
or their nominees will receive written notice of the Offer. The Rights issued to

                                       25
<PAGE>

foreign  Record Date  Shareholders  will be held by the  Subscription  Agent for
their accounts until  instructions  are received to exercise the Rights.  Rights
issued to foreign Record Date Shareholders will expire for the failure to submit
instructions to the Subscription Agent prior to or on the Expiration Date.

CERTAIN FEDERAL INCOME TAX CONSEQUENCES OF THE OFFER

The  following   discussion   summarizes   the  principal   federal  income  tax
consequences  of the  Offer  to  Record  Date  Shareholders.  It is based on the
Internal  Revenue  Code  of  1986,  as  amended  (the  "Code"),   U.S.  Treasury
regulations,   Internal  Revenue  Service  rulings  and  policies  and  judicial
decisions in effect on the date of this Prospectus,  all of which are subject to
change or differing  interpretation  possibl6y  with  retroactive  effect.  This
discussion does not address all federal income tax aspects of the Offer that may
be  relevant  to a  particular  shareholder  in light  of his or her  individual
circumstances  or to  shareholders  subject to special  treatment under the Code
(such as  insurance  companies,  financial  institutions,  tax-exempt  entities,
dealers in securities,  foreign corporations and persons who are not citizens or
residents  of the United  States),  and it does not address any state,  local or
foreign tax consequences.  Accordingly, each shareholder should consult his, her
or its own tax advisor as to the specific tax  consequences of the Offer to him,
her or it. Each  shareholder  should also review the  discussion  of certain tax
considerations  affecting the Fund and its shareholders set forth under "Federal
Taxation of the Fund and its  Shareholders"  below and under  "Taxation"  in the
SAI.

For federal  income tax  purposes,  neither the receipt nor the  exercise of the
Rights by Record Date  Shareholders  will result in taxable  income to them, and
they will realize no loss with respect to any Rights that expire  without  being
exercised.

A Record Date Shareholder's holding period for a Share acquired on exercise of a
Right will begin with the date of exercise.  A Record Date  Shareholder's  basis
for  determining  gain or loss on the sale of such a Share will equal the sum of
the  shareholder's  basis in the Right, if any, plus the  Subscription  Price. A
Record Date  Shareholder's  basis in a Right will be zero unless  either (1) the
fair market value of the Right on the date of distribution is 15% or more of the
fair market value on that date of the Shares with respect to which the Right was
distributed or (2) the shareholder elects, on his, her or its federal income tax
return for the taxable year in which the Right is received,  to allocate part of
the basis of those  Shares to the Right.  If either  clause (1) or (2)  applies,
then if the Right is exercised,  the Record Date  Shareholder will allocate his,
her or its basis in the Shares with  respect to which the Right was  distributed
between those Shares and the Right in proportion to their respective fair market
values on the date of  distribution.  A Record Date  Shareholder's  gain or loss
recognized  on a sale of a Share  acquired on the  exercise of a Right will be a
capital gain or loss (assuming the Share was held as a capital asset at the time
of sale)  and will be  long-term  capital  gain or loss if the Share was held at
that time for more than one year.


The foregoing is only a summary of certain federal income tax  consequences  and
does not describe  any state,  local or foreign tax  consequences  of the Offer.
Record Date  Shareholders  should consult their own tax advisors  concerning the
tax consequences of the Offer.


NOTICE OF NET ASSET VALUE DECLINE


As required by the SEC,  the Fund has  undertaken  to suspend the Offer until it
amends this Prospectus if, subsequent to May 24, 1999 (the effective date of the
Fund's  Registration  Statement of which this Prospectus is a part),  the Fund's
NAV  declines  more  than  10% from its NAV as of that  date.  Accordingly,  the
Expiration  Date  would  be  extended  and the Fund  would  notify  Record  Date
Shareholders  of any such  decline  and  permit  shareholders  to  cancel  their
exercise of Rights.


                                       26
<PAGE>

EMPLOYEE BENEFIT PLAN CONSIDERATIONS

Shareholders that are employee benefit plans subject to the Employee  Retirement
Income Security Act of 1974, as amended  ("ERISA")  (including  corporate profit
sharing/retirement  and savings plans,  plans for self-employed  individuals and
their employees,  and individual  retirement  accounts ("IRAs"))  (collectively,
"Retirement  Plans") should be aware that additional  contributions of cash to a
Retirement  Plan  (other  than  rollover   contributions  or  trustee-to-trustee
transfers  from other  Retirement  Plans) in order to exercise  Rights may, when
taken  together  with  contributions  previously  made,  be treated as excess or
nondeductible  contributions  subject to excise taxes. In the case of Retirement
Plans qualified under section 401(a) of the Code,  additional cash contributions
could cause violations of the maximum contribution limitations of section 415 of
the Code or other qualification  rules.  Retirement Plans in which contributions
are so limited should  consider  whether there is an additional  source of funds
available within the Retirement Plan,  including the liquidation of assets, with
which to exercise the Rights.  Because the rules  governing  plans are extensive
and  complex,  Retirement  Plans  contemplating  the  exercise of Rights  should
consult with their counsel prior to such exercise.

Retirement Plans and other tax exempt entities,  including  governmental  plans,
should  also be aware that if they borrow to finance  their  exercise of Rights,
they may become  subject to the tax on unrelated  business  taxable income under
section  511 of the Code.  If any  portion of an IRA is used as  security  for a
loan, that portion will be treated as a distribution to the IRA owner.

ERISA contains  fiduciary  responsibility  requirements,  and ERISA and the Code
contain prohibited  transactions  rules, that may impact the exercise of Rights.
Due to the  complexity  of these  rules  and the  penalties  for  noncompliance,
Retirement Plans should consult with their counsel regarding the consequences of
their exercise of Rights under ERISA and the Code.

DISTRIBUTION ARRANGEMENTS


PaineWebber  Incorporated,  1285 Avenue of the Americas,  New York,  New York, a
broker-dealer  and member of the National  Association  of  Securities  Dealers,
Inc., will act as the Dealer Manager for the Offer.  Under the terms and subject
to the  conditions  contained  in the Dealer  Manager  Agreement  dated the date
hereof,  the Dealer  Manager  will  provide  financial  advisory  and  marketing
services in  connection  with the Offer and will  solicit the exercise of Rights
and   participation   in  the   Over-Subscription   Privilege   by  Record  Date
Shareholders.  The Offer is not  contingent  upon any  number  of  Rights  being
exercised.  The Fund has  agreed to pay the Dealer  Manager a fee for  financial
advisory and marketing  services  equal to 1.25% of the  aggregate  Subscription
Price for each Share issued pursuant to the Offer,  and the Fund has also agreed
to pay broker-dealers, including the Dealer Manager, fees for their solicitation
efforts (the  "Solicitation  Fees") of 2.50% of the Subscription Price per Share
for each Share issued pursuant to the exercise of the Rights and pursuant to the
Over-Subscription   Privilege   as  a  result  of  their   soliciting   efforts.
Solicitation Fees will be paid to the broker-dealer designated on the applicable
portion of the Subscription Certificates or, in the absence of such designation,
to the Dealer Manager.

In  addition,  the Fund has  agreed to  reimburse  the  Dealer  Manager up to an
aggregate of $100,000 for its reasonable  expenses  incurred in connection  with
the Offer. The Fund and the Investment  Manger have each agreed to indemnify the
Dealer  Manager or  contribute  to losses  arising  out of  certain  liabilities
including  liabilities  under the Securities  Act. The Dealer Manager  Agreement
also  provides  that the Dealer  Manager will not be subject to any liability to
the Fund in rendering the services contemplated by such agreement except for any
act of bad faith,  willful  misconduct or gross negligence of the Dealer Manager
or  intentional  failure to perform  substantially  by the Dealer Manager of its
obligations and duties under such agreement.



                                       27
<PAGE>

The Fund has agreed not to offer or sell,  or enter into any  agreement to sell,
any equity or equity  related  securities of the Fund or securities  convertible
into  such  securities  for a period of 180 days  after  the date of the  Dealer
Manager Agreement,  except for the Shares issued in reinvestment of dividends or
other distributions or other limited circumstances.





IMPORTANT DATES TO         EVENT                          DATE
  REMEMBER
                           Record Date                    May 25, 1999

                           Subscription Period            May 25, 1999 to June
                                                          18, 1999*


                           Expiration Date and Pricing    June 18, 1999*
                           Date

                           Subscription Certificates and  June 18, 1999*
                           Payment for Shares Due**

                           Notice of Guaranteed Delivery  June 18, 1999*
                           Due

                           Payment for Guarantees of      June 23, 1999*
                           Delivery Due

                           Confirmation Mailed to         June 30, 1999*
                           Participants

                           Final Payment for Shares***    July 12, 1999*
- --------

 *  Unless the Offer is extended to a date no later than June 21.


** A Record Date  Shareholder  exercising  Rights must deliver by the Expiration
Date  either (i) a  Subscription  Certificate  and  payment for Shares or (ii) a
Notice of Guaranteed Delivery.

*** Additional  amount due from Record Date Shareholders (in the event the Final
Subscription Price exceeds the Estimated Subscription Price).

                                 USE OF PROCEEDS


If 6,081,223  Shares are sold at the Estimated  Subscription  Price of $____ per
Share,  the Proceeds of the Offer are estimated to be  approximately  $________,
after deducting  estimated expenses payable by the Fund,  including the fees and
expenses of the Dealer  Manager and other  offering  expenses  that in total are
estimated to be $596,200.  If the Fund increases the number of Shares subject to
subscription  by up to 25%,  or an  additional  1,520,306  Shares,  in  order to
satisfy   over-subscription   requests,   the   additional   Proceeds   will  be
approximately $________.

The  Investment  Manager  has  advised  the Fund  that it  anticipates  that the
Proceeds will be invested in accordance  with its  investment  objective and the
policies set forth under "Investment Objective and Policies" within three months
from the date of this Prospectus (but in no event later than six months from the
date of this Prospectus), depending on market conditions and the availability of
appropriate securities. The Proceeds of the Offer may be held in U.S. Government
securities and other  high-quality,  short-term money market  instruments  until
they are  invested  pursuant  to the  Fund's  investment  objective.  While  the
Proceeds are invested in such  securities,  the Proceeds will not be invested in
securities  consistent  with  the  Fund's  goal  of  seeking  long-term  capital
appreciation.  In addition,  consistent with the Fund's investment restrictions,
the  Proceeds of the Offer may be held  pending  permanent  investment  in other
instruments  including,   without  limitation,  S&P  500  futures.  These  other
investments may present a substantial  investment risk,  including the potential


                                       28
<PAGE>

that they may  decrease in value prior to the time they are  liquidated  and the
Proceeds are ultimately invested.


                        INVESTMENT OBJECTIVE AND POLICIES

The  investment  objective  of the  Fund  is to  seek  capital  appreciation  by
investing  substantially  all of its assets in equity and related  securities of
U.S.  and  foreign  Health  Science  Companies.  The Fund's  Investment  Manager
believes that the securities of Health Science Companies offer the potential for
capital   appreciation  based  upon  the  Investment   Manager's  projection  of
increasing  global   expenditures  for  health  science  products  and  services
resulting from enhanced consumer demand,  continuing  technological advances and
demographic trends indicating an aging population. The Fund's Investment Manager
also  believes that the  potential  for capital  appreciation  within the health
science  industries  will be driven by increased  focus on cost  containment and
productivity  enhancement.  An  investment  in the Fund  should  not  itself  be
considered   a  balanced   investment   program   and  is  intended  to  provide
diversification  for a more  complete  investment  program.  No assurance can be
given that the Fund will achieve its investment objective.

Under normal market conditions,  at least 80% of the Fund's total assets will be
invested in equity and  related  securities  of Health  Science  Companies.  The
principal industry groups of Health Science Companies are:


     o     Pharmaceuticals

     o     Biotechnology

     o     Medical equipment, devices and supplies

     o     Health care delivery


Health Science Companies also consist of those companies  principally engaged in
any other  industries  relating  to human  health or the growth or  survival  of
animals or plants and companies  principally  engaged in activities that utilize
technologies  that are the same as or similar to those  developed for or used by
Health   Science   Companies.   The  Fund  expects  to  invest  both  in  large,
well-established Health Science Companies with existing products and services as
well as in  smaller,  emerging  Health  Science  Companies,  including  start-up
companies and venture capital opportunities, which may offer limited products or
services or which are seeking to develop products, services or technologies.

Up to 20% of the Fund's  total  assets may be invested,  in the  aggregate,  in:
equity and related securities of companies  engaged,  but less than principally,
in the health  sciences or in  supplying  goods or  services  to Health  Science
Companies,  or of non-Health Science Companies which benefit from the growth and
development of Health Science Companies or in real estate investment trusts that
hold at least 50% of their  interests in facilities of Health Science  Companies
("Related  Companies");   non-convertible  debt  securities  of  Health  Science
Companies  and Related  Companies  that are not acquired as units  together with
equity  securities;   and  high  grade  U.S.  dollar  denominated  money  market
instruments having maturities of one year or less. Investment in non-convertible
debt  securities  (other  than  money  market  instruments)  of  Health  Science
Companies  and Related  Companies  (whether or not  acquired as units with other
securities)  is limited to 10% of the Fund's  total  assets.  Current  income is
generally not a consideration in the selection of investments.


                                       29
<PAGE>


The Fund has pending before the SEC an application  for an exemptive order that,
if  granted,  would  permit  the Fund to  participate  in an  interfund  lending
facility.  As  such,  the Fund may  lend  cash to  other  registered  investment
companies   (including   mutual  funds)  managed  by  the   Investment   Manager
("Affiliated  Funds"). If this application is granted, the Fund may from time to
time make such  loans to  Affiliated  Funds,  and may make such  loans  from the
Proceeds of the  Offering,  if such Proceeds  have not been  otherwise  invested
consistent with the Fund's objective.


The Fund may invest up to 25% of its total assets in securities  for which there
is no readily  available  secondary  market,  including  securities  acquired in
private   placements,   venture  capital   opportunities,   joint  ventures  and
partnerships.   Since  its  inception,  the  Fund  has  consistently  made  such
investments.

Up to 25% of the Fund's total assets,  measured at the time of purchase,  may be
invested in Foreign Securities.  Securities of Canadian issuers and ADRs are not
subject to this 25% limitation.

The Fund will, under normal conditions,  invest at least 65% of its total assets
in  issuers  that  are  organized  under  the laws of,  or that  maintain  their
principal  business  operations  in, at least three  countries,  one of which is
expected to be the United States.

"Equity and related  securities"  consist of: common,  preferred and convertible
preferred  stocks,  whether or not  voting;  partnership  interests;  securities
having equity  characteristics  such as rights,  warrants and  convertible  debt
securities,  whether  or not  issued by the same  issuer as the  security  to be
issued upon exercise or conversion;  non-convertible  debt  securities  that are
acquired  as  units  together  with  any  of  the  foregoing,   whether  or  not
transferable or separately  traded;  and short sale and hedge positions relating
to any of such securities.

The  Fund  may  utilize  certain  investment   practices,   such  as  repurchase
agreements,  when-issued and delayed delivery  transactions,  lending  portfolio
securities,  foreign  currency and other hedging  transactions  and short sales.
These investment  practices  involve certain risks. See "Additional  Information
About Its Investment Objective and Policies" located in the SAI.

For  temporary  purposes,  and  when,  in  the  Investment  Manager's  judgment,
conditions  in the  securities  markets  generally  or in  the  market  for  the
securities of Health  Science  Companies  would make  achievement  of the Fund's
investment objective  impracticable,  the Fund may assume a defensive investment
position.  During  these  periods,  the Fund may  without  limit  invest in U.S.
dollar-denominated, high grade money market instruments rated or, if unrated, in
the Investment  Manager's  opinion  comparable to instruments  rated, in the top
three rating categories utilized by at least one national recognized statistical
rating organization and having maturities at the time of purchase of one year or
less,  including securities issued or guaranteed by the United States Government
or one of its  agencies or  instrumentalities  ("U.S.  Government  Securities"),
certificates of deposit,  bankers'  acceptances,  commercial  paper,  short-term
corporate  securities,  and  repurchase  agreements  with  respect to any of the
foregoing. While the Fund is in a defensive position, the opportunity to achieve
capital  appreciation  will be limited,  and, to the extent that the  Investment
Manager's  assessment  of  market  conditions  is  incorrect,  the Fund  will be
foregoing the  opportunity to benefit from capital  appreciation  resulting from
increases in the value of equity investments; however, the ability to maintain a
defensive  investment  position provides the flexibility for the Fund to seek to
avoid capital loss during market downturns. It is impossible to predict when, or
for how long, any such investment position will be maintained.


                                       30
<PAGE>

INVESTMENT RESTRICTIONS

The Fund has adopted the following investment restrictions, which, together with
its investment  objective,  are  fundamental  policies  changeable only with the
approval of a "majority" of the Fund's outstanding voting securities. As defined
in the 1940 Act, this requires the  affirmative  vote of the holders of (a) more
than 50% of the outstanding Shares of the Fund, or (b) two-thirds or more of the
Shares  present at a meeting if more than 50% of the Fund's  outstanding  Shares
are represented at the meeting in person or by proxy,  whichever is less.  Under
these restrictions, the Fund may not:

      1. borrow  money or  issue senior  securities, except  that the  Fund  may
         borrow in an amount not  exceeding  15% of its total  assets to finance
         the  repurchase  of or tender offers for Shares or to pay dividends and
         other distributions, and may borrow for temporary purposes in an amount
         not  exceeding  5% of its total  assets (the Fund will not be deemed to
         have  issued a senior  security  by reason of  effecting  short  sales,
         lending securities,  purchasing  securities on a when-issued or delayed
         delivery basis, or engaging in hedging  transactions in accordance with
         its investment  policies,  or entering into collateral  arrangements or
         maintaining   margin   deposits   incident  to  any  of  the  foregoing
         practices);

      2. buy or sell commodities, commodity contracts, oil, gas or other mineral
         interests  or  exploration  programs  (however,  the Fund may  purchase
         securities  of companies  which invest in the  foregoing  and may enter
         into transactions in hedging instruments);

      3. buy or  sell  real  estate or  interests  therein  (however, securities
         issued by companies  which  invest in real estate or interests  therein
         may be purchased and sold);

      4. invest  in  any  company  for  the  purpose  of  exercising  control or
         management,  except  to the  extent  that  exercise  by the Fund of its
         rights under agreements related to portfolio securities would be deemed
         to constitute such control;

      5. engage in  the  underwriting of  any securities, except  insofar as the
         Fund may be deemed an  underwriter  under the Securities Act of 1933 in
         the sale of its Shares or in disposing of a portfolio security;

      6. make loans of money or  securities to any person, except  that the Fund
         may lend money through the purchase of securities (including repurchase
         agreements) in accordance with its investment policies,  and make loans
         of portfolio  securities  in an amount not  exceeding 25% of the Fund's
         total assets;

      7. with respect to 75% of its total assets, purchase the securities of any
         one issuer  (except U.S.  Government  Securities) if the purchase would
         cause the Fund to have  more  than 5% of the value of its total  assets
         invested  in the  securities  of such issuer or to own more than 10% of
         the outstanding voting securities of such issuer;

      8. invest in  the  securities of  other investment companies  in an amount
         exceeding  the  limitations  set  forth in the  1940 Act and the  rules
         thereunder;

      9. purchase a  security if such purchase  would cause more than 25% of its
         total assets to be invested in securities of issuers engaged in any one
         industry (as  determined by standard  industry  classification  codes),


                                       31
<PAGE>

         except that the Fund will, under normal market conditions,  invest more
         than 25% of its total  assets in the  securities  of  companies  in the
         groups of industries in which Health Science Companies are engaged; or

     10. pledge, hypothecate, mortgage or  otherwise encumber its assets, except
         to  secure   permitted   borrowings  or  for   collateral   and  margin
         arrangements associated with the Fund's investment practices.

The  percentage  limitations on  investments  set forth above,  as well as those
described  elsewhere  in this  Prospectus  and  SAI,  apply  only at the time of
investment  and require no action by the Fund as a result of subsequent  changes
in the value of investments or the total assets of the Fund.

SPECIAL INVESTMENT PRACTICES

The Fund may utilize the following special investment practices:

SHORT SALES. In furtherance of its objective of capital  appreciation,  the Fund
may effect  short sales of any  securities  which it has  authority to purchase,
subject  to the  limitation  that the Fund will not effect a short sale if, as a
result of such sale,  the current  market value of  securities  sold short would
exceed 25% of the Fund's total assets. Short sales are transactions in which the
Fund sells a security it does not own in anticipation of an expected  decline in
the price of that  security.  In such a  transaction,  the Fund must  borrow the
security to make  delivery to the buyer.  The Fund is  obligated  to replace the
borrowed  security  and may  realize a gain if it  purchases  the  security  for
replacement at a lower price. However, the price at which the Fund purchases the
security may be more or less than the price at which the security was sold.  The
Fund will incur a loss as a result of a short sale if the cost of purchasing the
borrowed security,  and transaction and carrying costs associated with the short
sale, are more than the amount realized from the short sale. Although the Fund's
potential  for gain as a result of a short sale is limited to the price at which
it sold the  security  short  less  the  cost of  borrowing  the  security,  its
potential for loss is theoretically  unlimited  because there is no limit to the
cost of replacing the borrowed security.

If the Fund borrows a security in order to enter into a short sale, the proceeds
of the short sale will be retained by a broker, as security for the borrowing to
the extent  necessary to meet margin  requirements,  until the short position is
closed out.  The Fund is also  required to pay to the lender of the security the
amount of any dividends or interest paid on the borrowed security. To borrow the
security,  the Fund also may be required to pay a premium,  which would increase
the cost of the security  sold short.  The amount of any gain will be decreased,
and the amount of any loss increased,  by the amount of any premium or dividends
or interest  paid on the borrowed  security that the Fund may be required to pay
in connection with the short sale.

A short sale "against the box" is a transaction  in which the Fund enters into a
short  sale of a  security  that the Fund owns or has the right to acquire at no
additional  cost.  The proceeds of the short sale are held by a broker until the
Fund delivers the security to close the short  position,  at which time the Fund
will receive the net proceeds from the sale.

When the Fund engages in short sales other than "against the box," the Fund will
"cover" its  position  in one of two ways.  The Fund may cover by holding a call
option on the security sold short having a strike price no higher than the price
at which the  security  was sold.  Alternatively,  the Fund may  maintain  in an
account  with its  custodian  a  segregated  amount  of cash or U.S.  Government
Securities  equal to the excess of (1) the market value of the  securities  sold
short at the time  they were sold  short,  over (2) any cash or U.S.  Government
Securities  required by the broker to be deposited as  collateral  in connection
with the short sale (not including the proceeds from the short sale).  Until the
borrowed security is replaced, the Fund will maintain this account at a level so
that the amount deposited in the account, plus the collateral deposited with the

                                       32
<PAGE>

broker,  will equal the current market value of the securities  sold short,  but
not less  than the  market  value of the  securities  at the time they were sold
short.


HEDGING.  For hedging  purposes,  the Fund may purchase and sell stock  options,
stock index futures, such as S&P 500 futures,  options on stock indices, options
on stock index futures,  forward foreign currency contracts and foreign currency
futures  contracts and related options  (collectively,  "Hedging  Instruments").
Hedging  Instruments may be used to attempt to reduce  investment risk by taking
an investment  position that is expected to move in the opposite  direction from
the  position  being  hedged.  The Fund may enter into hedging  transactions  in
connection with anticipated  purchases or sales of portfolio  securities or with
respect to anticipated  changes in the market prices for securities which are in
its portfolio.  To the extent the hedge is  successful,  a loss (or gain) on one
position will tend to be offset by a gain (or loss) on the other. The Investment
Manager will not engage in financial futures or related options transactions for
speculative purposes but only in an effort to hedge portfolio risks as described
above. The Fund will only invest in futures contracts and related options to the
extent that the Fund would not be required  thereby to register  with the United
States Commodity Futures Trading Commission as a commodity pool operator.  Under
current  regulations,  the Fund may not  purchase or sell  futures  contracts or
related  options if,  immediately  thereafter,  the sum of the amount of initial
margin deposits on the Fund's open regulated  options and futures  positions and
premiums  on open option  positions  thereon  that are not hedging  transactions
would exceed 5% of the market value of the Fund's total assets.


The  successful  use  of  Hedging  Instruments  depends  on the  ability  of the
Investment  Manager to  predict  the  direction  of the market and is subject to
various  additional risks. The investment  techniques and skills required to use
Hedging  Instruments  successfully  are different  from those required to select
equity securities for investment. The correlation between movements in the price
of the  Hedging  Instruments  and the price of the  securities  being  hedged is
imperfect and the risk from  imperfect  correlation  increases,  with respect to
stock  index  related  Hedging  Instruments,  as the  composition  of the Fund's
portfolio  diverges from the  composition of the index  underlying  such Hedging
Instruments.  If the Fund has  hedged  against  a  decline  in the  value of its
portfolio  securities,  the Fund  could  suffer a loss  which is only  partially
offset or not offset at all by an increase in the value of the Fund's  portfolio
securities. If the Fund has hedged an intended purchase of securities,  the Fund
could  suffer a loss  which is only  partially  offset or not offset at all by a
reduction in the price at which the securities are purchased. If the Fund hedges
a  proposed   purchase  of  securities  and  determines  not  to  purchase  such
securities,  any loss on the Hedging Instrument will not be offset. In addition,
the ability of the Fund to close out a position in a Hedging  Instrument depends
on a liquid  secondary  market.  There is no  assurance  that  liquid  secondary
markets will exist for any particular Hedging Instrument at any particular time.

The Fund may enter into  contracts to purchase or sell foreign  currencies  at a
future date ("forward contracts") foreign currency futures contracts, options on
such futures  contracts  and options on foreign  currencies  as a hedge  against
fluctuations in foreign exchange rates pending the settlement of transactions in
Foreign  Securities  or during the time the Fund  holds  Foreign  Securities.  A
forward foreign currency contract is an agreement between contracting parties to
exchange an amount of  currency at some future time at an agreed upon rate.  The
Fund will not attempt to hedge all of its foreign  portfolio  positions and will
enter into such transactions  only to the extent, if any, deemed  appropriate by
the Investment  Manager.  The Fund will not enter into a forward  contract for a
term of more than one year.  Investors  should be aware that  hedging  against a
decline in a currency  does not  eliminate  fluctuations  in the market value of
portfolio securities or prevent losses if the value of such securities declines.
Furthermore,  such hedging transactions preclude the opportunity for gain if the
hedged  currency should rise. No predictions can be made with respect to whether

                                       33
<PAGE>

the total of such  transactions will result in a better or a worse position than
had the Fund not entered into foreign currency hedges.

The Hedging  Instruments  that the Fund may use are described in the SAI,  which
contains  further  information  about  the  characteristics,   risks,   possible
benefits, and applicable limitations on the use of such Hedging Instruments.

REPURCHASE  AGREEMENTS.  In order to make  productive use of funds pending other
investments,  any of the types of high grade  debt  securities  permissible  for
purchase  by the Fund may be  acquired  subject to  repurchase  agreements  with
commercial banks with total assets in excess of $1 billion or securities dealers
with a net worth in excess of $50  million.  The  Investment  Manager  will also
consider  the  creditworthiness  of the  parties  with whom the Fund enters into
repurchase  agreements.  In a  repurchase  transaction,  at the  time  the  Fund
acquires a security, it simultaneously agrees to resell it to the bank or dealer
from which it was  purchased on a specific  future date.  The  repurchase  price
exceeds the purchase  price by an amount that  reflects an agreed upon  interest
rate  effective  for the period  during  which the  repurchase  agreement  is in
effect. Delivery pursuant to the resale typically will occur within one to seven
days of the purchase.  A repurchase  transaction is similar to a loan,  with the
security underlying the agreement serving as collateral.  The Fund requires that
securities  underlying  repurchase  agreements  be held by its  custodian  in an
amount having a value at least equal to the  repurchase  price.  The  Investment
Manager will monitor the  collateral  daily and, if its value declines below the
repurchase  price,  will  immediately  demand  that  additional   securities  be
transferred.  If such demand is not met within one day, the  securities  will be
sold by the Fund. If any party to a repurchase agreement fails to pay the agreed
upon resale price on the delivery  date, the Fund's risks include any decline in
the  value  of the  collateral  to an  amount  which  is less  than  100% of the
repurchase price, any costs of disposing of such collateral, and any loss from a
delay in  disposing  of the  collateral.  There is no limit on the amount of the
Fund's assets that may be subject to repurchase agreements.

                     RISK FACTORS AND SPECIAL CONSIDERATIONS


DILUTION:  NET ASSET VALUE AND  OWNERSHIP.  If you do not  exercise  all of your
Rights during the Subscription  Period, when the Offering is over you will own a
relatively  smaller percentage of the Fund than if you had exercised all of your
Rights.  The Fund cannot tell you precisely  how much smaller the  percentage of
the Fund  that you  would  own  because  the Fund  does not know how many of the
Fund's Record Date Shareholders will exercise their Rights and how many of their
Rights they will exercise.

Shareholders will experience an immediate dilution, which may be significant, of
the  aggregate  NAV of the  Shares  as a result of the  completion  of the Offer
because  the  Subscription  Price per Share will be less than the Fund's NAV per
Share on the Expiration  Date,  the Fund will incur expenses in connection  with
the Offer, and the number of Shares outstanding after the Offer will increase in
a greater  percentage  than the increase in the size of the Fund's assets.  This
dilution also will affect Record Date  Shareholders  to a greater extent if they
do not  exercise  their  Rights in full.  Although  it is not  possible to state
precisely the amount of any  decreases in either NAV or in ownership  interests,
because  it is not  known at this  time  what the NAV per  share  will be at the
Expiration  Date or what  proportion  of the  Shares  will be  subscribed,  such
dilution could be  significant.  Finally,  there may be dilution of earnings per
Share due to the increase in the number of shares  outstanding,  but only to the
extent  that  investments  of the  Proceeds of the Offer do not achieve the same
return as current  investments  held by the Fund. To the extent such investments
achieve a better  return  than  current  investments,  earnings  per Share  will
experience appreciation.


                                       34
<PAGE>

The following  example  assumes that all of the Shares are sold at the Estimated
Subscription  Price and after deducting all expenses  related to the issuance of
the Shares.

                      NAV per Share on  Dilution in Dollars  Percentage Dilution
                        May 21, 1999
Primary Subscription
or 6,081,223 Shares           18.63     $17,857,013          18.71%

Primary Subscriptions
and Over Allotment or
7,601,529 Shares              18.63     $22,321,267          15.76%


HEALTH SCIENCE COMPANIES.  Because the Fund intends to invest  substantially all
of its assets in equity and related securities of Health Science  Companies,  an
investor  should be aware of certain  special  considerations  and risk  factors
relating to  investment  in such  companies.  Investors  should also be aware of
considerations  and  risks  relating  to the  Fund's  investment  practices.  An
investment  in the Fund should not be considered a balanced  investment  program
and is  intended  to  provide  diversification  for a more  complete  investment
program. The Fund is not intended for investors seeking income.

Investment  in the  securities  of  Health  Science  Companies  entails  special
considerations  and risks. In addition to the risks associated with any strategy
seeking capital appreciation through investment in equity securities, the Fund's
portfolio will bear the additional  risk that many Health Science  Companies may
be subject to, and  possibly  adversely  affected  by, some of the same  general
trends relating to demand for health related  products and services and the same
regulatory,  economic, and political factors.  Certain health science industries
are  characterized  by single product focus and rapidly  changing  technologies.
These changes may render existing products and technologies  obsolete.  There is
also extensive government regulation of certain health science industries.  Many
of these  activities are funded or subsidized by federal and state  governments;
withdrawal or  curtailment  of this support could have an adverse  impact on the
profitability,  and market  prices,  of such  companies.  Changes in  government
regulation could also have an adverse impact.  Unanticipated  problems may arise
in connection  with the  development of new products or  technologies,  and many
such efforts may ultimately be unsuccessful.  In addition,  testing or marketing
products may require obtaining government approvals,  which may be a lengthy and
expensive process with an uncertain outcome.  Delays in generating  products may
result  in the  need  to  seek  additional  capital,  potentially  diluting  the
interests of existing  investors,  such as the Fund.  These various  factors may
result in abrupt  advances and declines in the  securities  prices of particular
companies  and,  in  some  cases,  may  have a broad  effect  on the  prices  of
securities of companies in  particular  health  science  industries or of Health
Science Companies generally.

INVESTMENTS  IN UNSEASONED  COMPANIES.  The Fund may invest in the securities of
smaller,  less  seasoned  companies.   These  investments  may  present  greater
opportunities  for growth but also involve  greater risks than  customarily  are
associated with investments in securities of more established companies. Some of
the  Health  Science  Companies  in which the Fund may invest  will be  start-up
companies which may have  insubstantial  operational or earnings  history or may
have limited products,  markets,  financial  resources or management depth. Some
may also be emerging  companies at the research  and  development  stage with no
products or  technologies  to market or approved for  marketing.  Securities  of
emerging Health Science Companies may lack an active secondary market and may be
subject to more abrupt or erratic  price  movements  than  securities of larger,
more established  companies or stock market averages in general.  Competitors of
certain  Health  Science  Companies,  which  may or may  not be  Health  Science
Companies,  may have substantially  greater financial resources than many of the
companies in which the Fund may invest.


                                       35
<PAGE>

SUBSTANTIAL  COMPETITION.  Intense  competition  exists within and among certain
health  science  industries,   including   competition  to  obtain  and  sustain
proprietary  technology  protection.  Health  Science  Companies  may be  highly
dependent on the strength of a patent to maintain  revenue and market share. The
complex  nature  of the  technologies  involved  can  lead to  patent  disputes,
including litigation that could result in a company losing an exclusive right to
a patent.  In addition,  there are numerous  Related  Companies and the Fund may
invest only a limited portion of its assets in the securities of such companies.
These  Related  Companies,  although  not  principally  engaged  in  the  health
sciences, may be large,  well-capitalized  companies that are engaged in certain
health  science  businesses.  Some of these  companies  may  have  substantially
greater capital, research and development,  manufacturing,  marketing, and human
resources  capabilities  than certain of the Health Sciences  Companies in which
the Fund may invest and may  represent  significant  long-term  competition  for
Health  Sciences  Companies.   Such  large  Related  Companies  may  succeed  in
developing technologies and products that are more effective or less costly than
any that may be developed by Health  Science  Companies and may also prove to be
more successful in production and marketing. Competition may increase further as
a result of potential  advances in the health sciences and greater  availability
of capital for investment in these fields.

PRODUCT  LIABILITY  EXPOSURE.  Certain  Health  Science  Companies  and  Related
Companies  in which the Fund may invest  will be exposed  to  potential  product
liability  risks that are  inherent in testing,  manufacturing,  marketing,  and
selling human  therapeutic  and diagnostic  products.  There can be no assurance
that a product  liability claim would not have a material  adverse effect on the
business, financial condition or securities prices of the companies in which the
Fund has invested.


FOREIGN  SECURITIES.  The Fund may  invest  substantially  all of its  assets in
Foreign Securities.  Many Foreign Securities may be less liquid and their prices
more volatile than  securities of  comparable  U.S.  companies.  The issuance of
Foreign  Securities and the activities of brokers are generally  subject to less
governmental  supervision and regulation than U.S.  securities and brokers,  and
commissions  on  Foreign   Securities  are  generally   higher  than  negotiated
commissions in the United States. In addition,  there may, in certain instances,
be delays in the settlement of transactions effected in foreign markets. Certain
countries  restrict  foreign  investments  in their  securities  markets.  These
restrictions may limit or preclude investment in certain countries or in certain
industries  or  market  sectors,  or may  increase  the  cost  of  investing  in
securities of particular companies.


Foreign companies are not generally subject to uniform accounting, auditing, and
financial reporting standards or to other regulatory  requirements comparable to
those  applicable  to  U.S.  companies.   Thus,  there  may  be  less  available
information  concerning non-U.S.  issuers of securities held by the Fund than is
available concerning U.S. companies.  In addition,  with respect to some foreign
countries  there  is  the  possibility  of  nationalization,   expropriation  or
confiscatory  taxation.  Income  earned in a foreign  nation  may be  subject to
taxation (including withholding taxes on interest and dividends), or other taxes
may be imposed with respect to  investments in Foreign  Securities.  Other risks
associated with  investments in Foreign  Securities  include  limitations on the
removal of  securities,  property or other assets of the Fund,  difficulties  in
pursuing legal remedies and obtaining judgments in foreign courts,  political or
social instability,  and diplomatic developments that could adversely affect the
Fund's investments in companies located in foreign countries.

CURRENCY  RISK.  The income and  capital  gains  received by the Fund on Foreign
Securities  generally  will  be in  non-U.S.  currencies.  The  computation  and
distribution of income and capital gains by the Fund,  however,  will be made in
U.S.  dollars.  Therefore,  the  Fund's  reported  NAV and its  computation  and
distribution  of  income  and  capital  gains in U.S.  dollars  will  vary  with
increases and decreases in the exchange rate between the currencies in which the
Fund has  invested and the U.S.  dollar.  A decline in any  particular  currency
against  the U.S.  dollar will cause a decline in the U.S.  dollar  value of the
Fund's holdings of securities  denominated in such currency and, therefore,  may

                                       36
<PAGE>

cause an overall decline in the Fund's NAV and net investment income and capital
gains, if any, to be distributed in U.S. dollars to shareholders by the Fund. In
addition,  the  computation of income and capital gains will be made on the date
of its accrual by the Fund  rather than on any later date on which the  proceeds
are converted into U.S. dollars. See "Taxation" in the SAI.


The rate of exchange  between the U.S. dollar and other currencies is determined
by many  factors,  including  the supply and demand for  particular  currencies,
central bank efforts to support particular currencies,  the movement of interest
rates,  the pace of activity in the industrial  countries,  including the United
States, and other economic and financial conditions affecting the world economy.
As discussed  above,  the Fund may enter into foreign  currency  related Hedging
Instruments  to seek to hedge against  fluctuations  in foreign  exchange  rates
pending the settlement of transactions in Foreign  Securities or during the time
the   Fund   holds   Foreign   Securities.   See   "Investment   Objective   and
Policies--Special Investment Practices--Hedging."


EURO CONVERSION.  The recent introduction of a new European currency,  the euro,
may result in future  uncertainties  for European  securities  in the markets in
which they trade and with respect to the operation of the Fund's portfolio.  The
euro was  introduced on January 1, 1999 by eleven  European  countries  that are
members of the European  Economic and Monetary Union. The transition to everyday
usage of the euro will  occur  during the period  from  January 1, 1999  through
December 31, 2001. The introduction of the euro will require the  redenomination
of European debt and equity  securities over a period of time,  which may result
in various accounting differences and/or tax treatments that otherwise would not
likely occur.  Additional questions are raised by the fact that certain European
Union  members,  including  the United  Kingdom,  did not  implement the euro on
January 1, 1999.  If the  remainder of the  transition to the euro does not take
place as  planned,  there  could be negative  effects,  such as severe  currency
fluctuations and market disruptions.

PORTFOLIO TURNOVER. There are no fixed limitations regarding portfolio turnover.
Frequency of portfolio turnover will, therefore, not be a limiting factor if the
Fund  considers  it  advantageous  to  purchase  or sell  securities.  The  Fund
anticipates  that its annual  portfolio  turnover rate will not exceed 200%. For
the year ended October 31, 1998, the Fund's  portfolio  turnover rate was 87%. A
higher rate of portfolio  turnover  involves  correspondingly  greater aggregate
payments for brokerage  commissions  than a lower rate,  which  expenses must be
borne by the Fund and its shareholders, while a lower rate of portfolio turnover
involves correspondingly lower aggregate payments and shareholder expenses.

ILLIQUID  INVESTMENTS.  The Fund is  permitted  to invest up to 25% of its total
assets in securities for which there is no readily  available  secondary market.
The risk of investing in such  securities  generally is greater than the risk of
investing in the securities of widely held,  publicly traded companies.  Certain
of these  securities may be restricted  securities and have legal or contractual
restrictions on resale.  Restricted  securities may not be sold except in exempt
transactions  or in a public  offering  registered  under the  Securities Act of
1933. Adverse conditions in the securities markets at certain times may preclude
a public  offering of an  issuer's  unregistered  securities.  Lack of an active
secondary market and resale restrictions may result in the inability of the Fund
to sell a  security  at a fair price and may  substantially  delay the sale of a
security that the Fund seeks to sell. In addition,  these securities may exhibit
greater price  volatility  than  securities for which  secondary  markets exist.
Companies  whose  securities are not publicly traded are not subject to the same
disclosure  and other legal  requirements  as are  applicable to companies  with
publicly  traded  securities.  Restricted  securities  eligible  for  resale  to
qualified institutional buyers pursuant to Rule 144A under the Securities Act of
1933 that are determined to be liquid by the Board, or by the Investment Manager
under  Board-approved  guidelines,  are  not  subject  to  this  25%  of  assets
limitation. Under guidelines to determine whether securities eligible for resale
under  Rule  144A  are  liquid,   factors  such  as  trading  activity  and  the

                                       37
<PAGE>

availability of price  quotations will be considered.  If trading  activity in a
Rule 144A security  purchased by the Fund  declines,  the Fund's holding in that
security may become illiquid.

Securities of many Health Science  Companies are traded in the  over-the-counter
market, on regional stock exchanges,  and on foreign securities exchanges.  Such
markets and exchanges may have low trading volume, and securities traded on such
markets  and  exchanges  may  experience  abrupt and  erratic  price  movements.
Determinations as to whether a "readily available secondary market" exists for a
particular security will be made by the Board or by the Investment Manager under
Board-approved  guidelines.  Since its inception, the Fund has consistently made
such investments.


                                       37
<PAGE>

JUNK BONDS AND  UNRATED  DEBT  SECURITIES.  The Fund may invest up to 10% of its
total assets in the  aggregate,  in  non-convertible  debt  securities of Health
Science Companies and Related Companies.  These securities and other investments
in such companies may be rated as low as C in the rating categories  established
by  Standard & Poor's and  Moody's or may be  unrated,  if deemed of  comparable
credit quality by the Investment Manager.  These securities,  which are commonly
referred  to as  "junk  bonds,"  are  regarded,  on  balance,  as  predominantly
speculative  in terms of the  capacity  of the issuer to pay  interest  or repay
principal in accordance with the terms of the obligation and accordingly involve
more credit risk than  securities  rated in the higher rating  categories.  Such
debt  securities are dependent upon  favorable  business,  financial or economic
conditions,  may be  subordinated  to senior  debt and can be regarded as having
extremely poor prospects of ever retaining any real investment standing.

The  market  prices of such  securities  tend to  reflect  individual  corporate
developments  to a greater extent than do securities  rated in the higher rating
categories,  which react  primarily  to  fluctuations  in the  general  level of
interest rates. Junk bonds also tend to be more sensitive to economic conditions
than higher  rated  securities.  Adverse  publicity  and  investor  perceptions,
whether or not based on fundamental  analysis,  regarding junk bonds may depress
the prices for such securities.  These and other factors adversely affecting the
market prices of such securities will adversely affect the Fund's NAV.  Although
some risk is inherent in all securities  ownership,  holders of debt  securities
have a claim  on the  assets  of the  issuer  prior  to the  holders  of  equity
securities.  Therefore,  an investment in debt securities generally entails less
risk than an investment in equity securities of the same issuer.

Junk bonds are frequently  issued by  corporations  in the growth stage of their
development.   They  may  also  be  issued  in   connection   with  a  corporate
reorganization  or a corporate  takeover.  Companies that issue such  securities
often are highly  leveraged and may not have available to them more  traditional
methods  of  financing.  Therefore,  the  risk  associated  with  acquiring  the
securities  of such  issuers  generally  is greater than is the case with higher
rated securities.  For example, during an economic downturn such issuers may not
have  sufficient  revenues  to meet  their  interest  payment  obligations.  The
issuer's ability to service its debt obligations may also be adversely  affected
by specific  corporate  developments,  the issuer's  inability to meet  specific
projected business forecasts or the unavailability of additional financing.  The
risk of loss from default by the issuer is significantly greater for the holders
of such securities  because such securities are often unsecured and subordinated
to other creditors of the issuer.

The Fund may have difficulty disposing of junk bonds and unrated debt securities
because they may not have an active secondary market.  The market for junk bonds
has been  subject  to periods of  illiquidity.  The lack of an active  secondary
market may have an  adverse  effect on market  prices and the Fund's  ability to
dispose of particular issues and may also make it more difficult for the Fund to
obtain accurate market quotations for purposes of valuing these securities.

                                       38
<PAGE>


NET  ASSET  VALUE  DISCOUNT.  Shares  of  closed-end  funds,  such as the  Fund,
frequently  trade at a discount  from their NAV;  that is, the market  price per
share is less  than the value  per  share of the net  assets  of the fund.  This
characteristic is a risk separate and distinct from the risk that the Fund's NAV
will  decrease as a result of its  investment  activities.  Moreover,  investors
expecting to sell their Shares during the course of the Offering should be aware
that there is a greater risk that this discount,  which may increase  during the
Offering,  will adversely  affect them.  This  increased risk is because,  among
other things,  the market price per Share may reflect the  anticipated  dilution
that will result from this Offering.  The Fund cannot predict whether the Shares
will trade at a discount or premium to NAV after completion of the Offering. SEE
"Trading and Net Asset Value Information above."



If, at any time, Shares are trading at a substantial discount from NAV, the Fund
may take action to seek to reduce or eliminate  the  discount  from NAV at which
Shares are trading. Such actions could include,  among other things,  purchasing
Shares in open market  transactions or pursuant to a cash tender offer. There is
no assurance that any such actions would be taken or that, if undertaken,  would
reduce or eliminate any such discount. In addition, the Board could recommend to
Fund shareholders that the Fund could convert to an open-end investment company.
Conversion to an open-end  investment  company would make the Shares  redeemable
upon  demand by  shareholders  at prices  based upon the then  current  NAV.  If
converted to an open-end  fund, the Shares would no longer be listed on the NYSE
and the Fund would be required to modify certain of its investment policies. See
"Conversion to Open-End Status."

DIVIDENDS & OTHER DISTRIBUTIONS.  Based on current market condition  information
provided by the  Investment  Manager,  the Board of Trustees  believes  that the
Offer will not result in a change in the Fund's  current  level of dividends per
Share for the foreseeable  future.  The Board of Trustees has agreed to maintain
an annual  dividend  of at least 10% until  February  19,  2001  pursuant to its
Quarterly  Distribution  Policy.  However,  after  that  date,  there  can be no
assurance  that the Fund will maintain its current level of dividends per Share,
and  thereafter  the Board of Trustees may, in its sole  discretion,  change the
Fund's  current  dividend  policy or its current level of dividends per Share in
response to market or other conditions.  Further, there can be no assurance that
the Fund's total return will exceed 10% on an annual basis and thus the Fund may
return a shareholder's capital investment in the form of a distribution.


YEAR 2000.  INVESCO has committed  substantial  resources  and made  significant
progress  toward  making  sure its  computer  systems  will  continue to operate
smoothly through the year 2000, and expects that its business partners also will
be prepared for the year 2000.  While INVESCO does not anticipate  interruptions
in its business,  investors  should be aware of the possible risks. As is widely
known,  there is a chance  that some  computer  systems may not  function  after
December  31, 1999  because  they fail to  recognize  dates in the year 2000 and
beyond.  If a system at INVESCO or one of its business  partners should fail, it
could  adversely  affect the Fund.  In addition,  the markets for, or values of,
securities in which the Fund invests  could be affected by computer  failures on
or after January 1, 2000.  While INVESCO cannot make  assurances  that this will
not happen,  it continues to  thoroughly  analyze the  securities  that the Fund
invests in, including the possible effects of the year 2000 computer problems on
a company or the market the security trades in.

WHEN-ISSUED AND FORWARD  DELIVERY  SECURITIES.  Securities may be purchased on a
"when-issued" or on a "forward delivery" basis, which means that the obligations
will be  delivered  at a future  date  beyond  customary  settlement  time.  The
commitment  to purchase a security  for which  payment  will be made on a future
date may be deemed a separate security.  Although the Fund is not limited in the
amount of  securities  for which it may have  commitments  to  purchase  on such
basis, it is expected that in normal circumstances the Fund will not commit more
than  30% of its  assets  to  such  purchases.  The  Fund  does  not pay for the
securities until received or start earning interest on them until it is notified
of the  settlement  date.  In order to  invest  its  assets  immediately,  while

                                       39
<PAGE>

awaiting delivery of securities  purchased on such basis, the Fund will normally
invest in short-term  securities that offer same-day settlement and earnings but
that may bear interest at a lower rate than longer-term securities.

These  transactions  are  subject  to  market  fluctuation;  the  value  of  the
securities at delivery may be more or less than their purchase price, and yields
generally available on comparable  securities when delivery occurs may be higher
than yields on the securities  obtained pursuant to such  transactions.  Because
the Fund relies on the buyer or seller,  as the case may be, to  consummate  the
transaction,  failure by the other party to complete the  transaction may result
in the Fund's missing the  opportunity of obtaining a price or yield  considered
to be  advantageous.  The Fund will make  commitments to purchase  securities on
such basis only with the intention of actually  acquiring these securities,  but
it may  sell  such  securities  prior  to the  settlement  date if such  sale is
considered to be advisable.  When the Fund engages in "when issued" and "forward
delivery"  transactions,  it will do so for the purpose of acquiring  securities
for its portfolio  consistent with its investment objective and policies and not
for the purpose of investment leverage.

The SEC generally  requires that when  investment  companies,  such as the Fund,
effect  transactions of the foregoing nature, they must either segregate cash or
liquid  portfolio  securities  in the  amount  of their  obligations  under  the
foregoing  transactions  or cover such  obligations by maintaining  positions in
portfolio  securities,  futures contracts or options that would serve to satisfy
or offset  the risk of such  obligations.  When  effecting  transactions  of the
foregoing  nature,  the Fund will comply with such segregation or asset coverage
requirements.  There is no limitation as to the  percentage of the Fund's assets
that may be invested in such transactions.

                             MANAGEMENT OF THE FUND

INVESTMENT MANAGER


INVESCO has served as the Fund's investment adviser since February 4, 1998 under
an investment advisory agreement ("Investment Management  Agreement").  Prior to
that time, INVESCO Trust Company ("ITC"),  then a wholly owned subsidiary of the
Investment  Manager,  served as the Fund's  investment  adviser.  The  principal
address of the Investment  Manager is 7800 E. Union Avenue,  Suite 800,  Denver,
Colorado 80237.  INVESCO is an indirect wholly owned  subsidiary of AMVESCAP PLC
("AMVESCAP"),  a publicly traded holding company that, through its subsidiaries,
engages in the business of investment  management on an international  basis. As
part of  AMVESCAP,  INVESCO  draws on the  organization's  global  presence  and
expertise  to  deliver  portfolio  management  and  investment  services  to its
clients.  AMVESCAP  maintains  offices  around the world,  including  the United
States,  London,  Eastern Europe, Latin America,  Hong Kong and Tokyo.  AMVESCAP
offers a broad array of products and services to  institutions  and  individuals
through all major  distribution  channels in over 30 countries.  Recent  mergers
with  major  firms  such as AIM  Management  Group  Inc.,  GT Global  Inc.,  and
Chancellor LGT Asset Management, Inc. (formerly the distributor of the GT Global
Funds and the asset  management  division of  Liechtenstein  Global  Trust,  AG,
respectively) have positioned AMVESCAP as one of the world's largest independent
fund management companies, adding to its already-significant presence in Europe,
Asia and North  America.  As of December  31, 1998,  aggregate  assets under the
management of AMVESCAP and its affiliates worldwide exceeded $275 billion. As of
that same  date,  INVESCO  managed  or  administered  assets of more than  $21.2
billion,  including 15 registered open-end investment companies with 53 separate
portfolios.  INVESCO has built a global  reputation  by  providing  professional
investment  management to some of the world's largest institutions and more than
a million individual investors.  INVESCO provides investors with the perspective
gained from more than 65 years of helping clients pursue their financial goals.


                                       40
<PAGE>

The  Investment  Manager  determines the  composition  of the Fund's  portfolio,
places  all  orders  for the  purchase  and  sale of  securities  and for  other
transactions,  and oversees the  settlement of the Fund's  securities  and other
portfolio  transactions.  The  Investment  Manager also provides  administrative
services to the Fund. These include, among other things,  providing officers and
office space, preparing or assisting in preparing materials for shareholders and
regulatory  bodies and  overseeing  the  provision to the Fund of custodial  and
accounting services.

John  Schroer is the  portfolio  manager for the Fund.  Mr.  Schroer  joined the
Investment  Manager in 1992 and  became a Senior  Vice  President  of INVESCO in
1996. In addition to Mr. Schroer's  responsibilities as portfolio manager of the
Fund, he also manages the INVESCO  Strategic  Health  Sciences Fund. Mr. Schroer
has been an officer of the Fund since January 1996.

Mr.  Schroer  received  his B.S.  and  M.B.A.  degrees  from the  University  of
Wisconsin-Madison.  He began his investment  management  career in 1990 with the
Trust  Company of the West as an investment  analyst.  He was  eventually  given
additional  responsibilities  by the Trust Company of the West in Los Angeles as
Assistant  Vice President with  analytical  responsibilities  in the health care
industry.

INVESTMENT MANAGEMENT AGREEMENT

Under the management agreement, the Investment Manager is responsible to provide
investment  advice to the Fund and, in general,  to conduct the  management  and
investment program of the Fund under the supervision and control of the Board of
Trustees.  In addition,  the  Investment  Manager is required to furnish  office
facilities  and  equipment  to the Fund and to supply  certain  other  services,
including  all  facilities  and  personnel  necessary  to provide  the  services
required to be rendered by the Investment Manager.


On February 3, 1998, the Board of Trustees and the Investment  Manager agreed to
add a breakpoint to the investment  management  fee, such that the Fund pays the
Investment  Manager a fee based on an annual rate of 1.00% on the Fund's  ending
daily net  assets up to and  including  $500  million,  and 0.90% on the  Fund's
ending  daily net assets in excess of $500  million.  For the fiscal  year ended
October  31,  1998,  the  Fund  paid  INVESCO  investment   management  fees  of
$5,556,255.  Additionally,  in accordance with an Administrative  Agreement, the
Fund pays the Investment Manager a monthly fee based on the annual rate of 0.10%
on the  Fund's  ending  daily net assets for  administrative  services.  For the
fiscal year ended October 31, 1998, the Fund paid INVESCO administrative fees of
$250,000. The fee for investment management and administrative  services are, in
the  aggregate,  higher  than  those  paid by most  U.S.  investment  companies,
including open-end investment companies,  although they are generally comparable
to those paid by other specialized equity, closed-end funds.

The Board of Trustees  noted that the  Investment  Manager will benefit from the
Offer  because  its fees for  investment  management  services  are based on the
average daily net assets of the Fund. It is not possible to state  precisely the
amount of  additional  compensation  the  Investment  Manager  will receive as a
result of the Offer  because it is not known how many Rights  will be  exercised
and because the Proceeds of the Offer will be invested in  additional  portfolio
securities  that may  fluctuate  in value.  However,  in the event  that all the
Rights are exercised in full, including the additional 1,520,306 Shares by which
the Board,  in its  discretion,  may increase the Offer,  based on the Estimated
Subscription Price of $___, the Investment Manager would receive additional fees
for investment  management  services of approximately $___ per annum as a result
of the increase in assets under management.


The  Chairman  of the Board of  Trustees,  Charles W. Brady,  as an  "interested
person"  of the  Fund  and of  other  funds  in the  INVESCO  complex,  receives

                                       41
<PAGE>

compensation as an officer of companies  affiliated  with INVESCO,  but does not
receive any trustee fees or other compensation from the Fund or from other funds
in the INVESCO complex for his service as a Trustee or Director.

Under the  management  agreement,  the Fund pays  certain of its other costs not
paid by the  Investment  Manager,  including  (i) interest and taxes,  including
issue and  transfer  taxes,  incurred by or levied on the Fund;  (ii)  insurance
premiums for  fidelity and other  coverage  requisite to its  operations;  (iii)
compensation  and  expenses  of its  Trustees  other  than those  associated  or
affiliated  with the  Investment  Manager;  (iv) legal and audit  expenses;  (v)
custodian, dividend paying agent, registrar and transfer agent fees and expenses
(including  charges and expenses of the Fund's  Reinvestment Plan) and brokerage
commissions,   if  any;  (vi)  certain  fees  and  expenses,   incident  to  the
registration,  under  Federal law, of the Shares for public sale;  (vii) certain
expenses  incidental  to holding  meetings  of the Fund's  shareholders;  (viii)
payments under the Fund's  administrative  services agreement with INVESCO; (ix)
fees and  expenses of listing and  maintaining  the listing of the Shares on any
national  securities  exchange;  (x) the cost of certificates  representing  the
Shares;  and (xi)  such  non-recurring  expenses  as may  arise,  including  any
litigation affecting the Fund and the legal obligation that the Fund may have to
indemnify its officers and Trustees with respect thereto.

The  management  agreement  provides  that the  Investment  Manager shall not be
liable for any error of judgment or mistake of law, or for any loss  suffered by
the Fund in  connection  with the  matters  to which  the  management  agreement
relates,  except a loss resulting from willful  misfeasance,  bad faith or gross
negligence  on the part of the  Investment  Manager  in the  performance  of its
obligations and duties or by reason of its reckless disregard of its obligations
and duties under the management agreement.

The management agreement may be terminated without penalty upon sixty (60) days'
written notice by either party, or by a vote of the majority of the Shares,  and
automatically terminates in the event of its assignment.

                                PORTFOLIO TRADING

The  Investment  Manager  places  orders for the purchase and sale of securities
with  brokers  and  dealers  based  upon  its  evaluation  of  their   financial
responsibility  subject to their  ability to effect  transactions  at  favorable
prices. The Investment Manager evaluates the overall reasonableness of brokerage
commissions and markups paid by reviewing the quality of executions  obtained on
the Fund's portfolio transactions,  viewed in terms of the size of transactions,
prevailing  market  conditions  in the security  purchased or sold,  and general
economic and market  conditions.  In seeking to ensure that the  commissions and
markups  charged  to the Fund are  consistent  with  prevailing  and  reasonable
brokerage  commissions  or markups,  the  Investment  Manager also  endeavors to
monitor brokerage  industry practices with regard to the commissions and markups
charged  by  broker/dealers  on  transactions   effected  for  other  comparable
institutional   investors.   While  the  Investment   Manager  seeks  reasonably
competitive  rates,  the Fund does not  necessarily  pay the lowest  commission,
spread or markup available.

Consistent  with the  standard  of  seeking  to obtain  favorable  execution  on
portfolio  transactions,  the Investment Manager may select brokers that provide
research  services to effect such  transactions.  Research  services  consist of
statistical and analytical reports relating to issuers,  industries,  securities
and  economic  factors and trends,  which may be of  assistance  or value to the
Investment Manager in making informed  investment  decisions.  Research services
prepared and  furnished  by brokers  through  which the Fund effects  securities
transactions  may be used by the  Investment  Manager  in  servicing  all of its
accounts  and not all such  services  may be used by the  Investment  Manager in
connection with the Fund.


                                       42
<PAGE>

In  recognition  of the  value of the  above-described  brokerage  and  research
services provided by certain brokers,  the Investment  Manager,  consistent with
the standard of seeking to obtain the best execution on portfolio  transactions,
may place orders with such brokers for the  execution  of Fund  transactions  on
which the  commissions  are in excess of those  which other  brokers  might have
charged for effecting the same transactions.

One or more of the other accounts which the Investment  Manager manages may own,
from time to time, the same  investments as the Fund.  Investment  decisions for
the Fund are made independently from those of such other accounts; however, from
time to time, the same investment decision may be made for more than one company
or  account,  including  the  Fund.  When  two or more  companies  or  accounts,
including the Fund, seek to purchase or sell the same securities, the securities
actually purchased or sold will be allocated among the companies and accounts on
a good faith  equitable  basis by the  Investment  Manager in its  discretion in
accordance with the accounts' various investment objectives. In some cases, this
system may adversely affect the price or size of the position obtainable for the
Fund. In other cases,  however, the ability of the Fund to participate in volume
transactions may produce better execution for the Fund. It is the opinion of the
Board that this advantage,  when combined with the other benefits  available due
to the Investment Manager's  organization,  outweighs any disadvantages that may
be said to exist from exposure to simultaneous transactions.

Transactions  in foreign  securities  markets  generally  involve the payment of
fixed  brokerage  commissions,  which are usually higher than  commission  rates
available  in the United  States.  In such  transactions,  the Fund will seek to
obtain prompt execution of orders at the most favorable net price.

                                 NET ASSET VALUE

The Fund  calculates  the NAV of its  Shares  daily and makes  that  information
available  for  publication.  Currently,  the WALL STREET  JOURNAL and  BARRON'S
publish NAVs for  closed-end  funds each week.  NAV per Share will be determined
each day on which the NYSE is open,  as of the close of trading on the NYSE that
day, and is calculated by dividing the aggregate value of all securities held by
the Fund and its other assets (including  dividends and interest accrued but not
collected) less its liabilities  (including  accrued  expenses) by the number of
outstanding  Shares. All assets and liabilities  initially  expressed in foreign
currencies  will be converted into U.S.  dollars at the mean between the bid and
offer prices of such currencies against U.S. dollars last quoted by a major bank
selected by the Fund's custodian.  Securities traded on securities exchanges are
valued at their last sale prices as of 4:00 P.M., Eastern time, on the exchanges
where  such  securities  are  primarily   traded.   Securities   traded  in  the
over-the-counter market and listed securities for which no sales are reported on
a particular  day are valued at their bid prices (or for debt  securities  yield
equivalents  thereof)  obtained from one or more dealers making markets for such
securities.  If market quotations are not readily available,  a security will be
valued at fair value as determined  in good faith by, or under the  supervision,
of the Board of Trustees.  Debt securities will be valued in accordance with the
procedures above, that may include the use of valuations  furnished by a pricing
service that employs a matrix to determine  valuations for normal  institutional
size trading units. Prior to utilizing a pricing service,  the Board of Trustees
will review the methods  used by such service to assure  itself that  securities
will  be  valued  at  their  fair  values.  The  Board  of  Trustees  also  will
periodically  monitor  the  methods  used  by any  such  pricing  service.  Debt
securities  with  remaining  maturities of 60 days or less will,  absent unusual
circumstances,  be  valued  at  amortized  cost,  so long as such  valuation  is
determined by the Board of Trustees to represent fair value.  Futures  contracts
and options thereon,  which are traded on commodities  exchanges,  are valued at
their settlement value as of the close of such commodities exchanges.


                                       43
<PAGE>

Trading in Foreign  Securities  generally is  completed,  and thus the values of
such securities are determined, prior to the close of the NYSE. Foreign currency
exchange rates are also generally  determined  prior to the primary close of the
NYSE. On occasion,  the values of such securities and such exchange rates may be
affected by events occurring between the time as of which determinations of such
values or such exchange  rates are made and the primary close of the NYSE.  When
such events  materially  affect the values of securities held by the Fund or its
liabilities,  such  securities and  liabilities  will be valued at fair value as
determined in good faith by, or under the supervision of, the Board of Trustees.

            DIVIDENDS AND OTHER DISTRIBUTIONS; DIVIDEND REINVESTMENT
                             AND CASH PURCHASE PLAN


Shareholders   who  have   Shares   registered   directly  in  their  own  names
automatically  participate in the Fund's  Reinvestment Plan, unless and until an
election  is made to withdraw  from the  Reinvestment  Plan as herein  provided.
EquiServe,  Inc.  (the  "Agent")  acts as agent under the  Reinvestment  Plan on
behalf  of  participating  shareholders.  Shareholders  who do not  wish to have
distributions  automatically  reinvested should so notify  EquiServe,  Inc., 150
Royall Street Mail Stop 45-02-61, Canton, MA 02021. Under the Reinvestment Plan,
all  of the  Fund's  dividends  and  other  distributions  to  shareholders  are
reinvested in full and fractional  Shares as described  below. A shareholder who
owns Shares  registered in his/her  broker's or nominee  name,  and whose broker
does not provide facilities for a dividend reinvestment program, may be required
to have his/her Shares registered in his/her own name in order to participate in
the Reinvestment Plan.  Shareholders  wishing to participate in the Reinvestment
Plan whose  Shares are held in the name of a broker or  nominee  should  consult
their brokers as to how to accomplish dividend reinvestment.


The Board  has  implemented  a  Quarterly  Distribution  Policy,  which  entails
quarterly  payments of  dividends  in an amount equal to 2.5% of the Fund's NAV.
The first dividend to be paid on Shares  acquired on exercise of the Rights will
be the first  quarterly  dividend,  the record date for which  occurs  after the
issuance of the Shares.

Whenever  the Fund  declares  an  income  dividend  or a  capital  gain or other
distribution  (collectively,  "Dividends")  in  cash,  non-participants  in  the
Reinvestment  Plan will receive cash and participants in the  Reinvestment  Plan
will receive the equivalent in Shares.  Whenever the Fund declares  Dividends in
additional   unissued  but  authorized  Shares  ("Newly  Issued  Shares"),   all
Shareholders (including  non-participants in the Reinvestment Plan) will receive
Newly  Issued  Shares and  participants  in the  Reinvestment  Plan will receive
Shares.   In  either  instance,   the  Shares  received  by  Reinvestment   Plan
participants  will be  acquired  by the  Agent  for the  participant's  account,
depending upon the circumstances  described below, either (i) through receipt of
Newly Issued  Shares or (ii) by the purchase of  outstanding  Shares on the open
market ("Open-Market Purchases") on the NYSE or elsewhere. Open-Market Purchases
will be made only if the Fund declares a Dividend payable only in cash.

If, on the payment  date for a  Dividend,  the NAV per Share is equal to or less
than the  market  price per Share plus  estimated  brokerage  commissions  (such

                                       44
<PAGE>

condition being referred to herein as "Market Premium"), the Agent will purchase
Newly Issued Shares from the Fund on behalf of the Reinvestment Plan participant
at a price per  Share  equal to the  greater  of the NAV per Share or 95% of the
then current market price per Share. This discount from the current market price
reflects  savings in underwriting  and other costs that the Fund would otherwise
incur to raise additional capital.

If, on the payment  date for a Dividend,  the NAV per Share is greater  than the
market  price per Share  (such  condition  being  referred  to herein as "Market
Discount"),  the Agent will  endeavor  to invest the  Dividend  amount in Shares
acquired on behalf of the participants in Open-Market Purchases. In the event of
a Market  Discount on the payment date,  the Agent will have up to 30 days after
the payment date to invest the Dividend amount in Shares acquired in Open-Market
Purchases.

Registered shareholders who acquire their Shares in open-market transactions and
who do not wish to have  their  Dividends  automatically  reinvested  should  so
notify the Fund in  writing.  If a  shareholder  has not  previously  elected to
receive cash  Dividends and the Agent does not receive  notice of an election to
receive cash Dividends prior to the record date of any Dividend, the shareholder
will automatically receive such Dividends in additional Shares.

Participants in the Reinvestment Plan may withdraw from the Reinvestment Plan by
providing  written  notice to the Agent at least 30 days prior to the applicable
Dividend payment date. When a participant  withdraws from the Reinvestment Plan,
or upon termination of the Reinvestment Plan as provided below, certificates for
whole Shares credited to his/her account under the Reinvestment  Plan will, upon
request, be issued.  Whether or not a participant requests that certificates for
whole Shares be issued,  a cash payment will be made for any fraction of a Share
credited to such account.

The Agent will maintain all shareholder  accounts in the  Reinvestment  Plan and
furnish written  confirmations  of all  transactions in the accounts,  including
information  needed by shareholders for personal and tax records.  Shares in the
account  of each  Reinvestment  Plan  participant  will be held by the  Agent in
non-certificated  form in the name of the  participant,  and each  shareholder's
proxy will include those Shares  purchased  pursuant to the  Reinvestment  Plan.
Each participant,  nevertheless, has the right to receive certificates for whole
Shares owned.  The Agent will  distribute  all proxy  solicitation  materials to
participating shareholders.

In the case of  shareholders,  such as banks,  brokers  or  nominees,  that hold
Shares  for  others  who  are  the  beneficial   owners   participating  in  the
Reinvestment  Plan, the Agent will administer the Reinvestment Plan on the basis
of the number of Shares certified from time to time by the record shareholder as
representing the total amount of Shares registered in the shareholder's name and
held for the account of  beneficial  owners  participating  in the  Reinvestment
Plan.

There will be no charge to  participants  for  reinvesting  Dividends other than
their share of brokerage  commissions as discussed  below.  The Agent's fees for
administering  the Reinvestment  Plan and handling the reinvestment of Dividends
will be paid by the Fund. Each participant's  account will be charged a PRO-RATA
share of brokerage  commissions incurred with respect to the Agent's Open-Market
Purchases in connection with the  reinvestment of Dividends.  Brokerage  charges
for  purchasing  small  amounts of Shares for  individual  accounts  through the
Reinvestment  Plan are expected to be less than the usual brokerage  charges for
such  transactions  because  the Agent  will be  purchasing  Shares  for all the
participants  in  blocks  and  prorating  the  lower   commission  that  may  be
attainable.


The automatic  reinvestment  of Dividends will not relieve  participants  of any
income tax that may be  payable  on such  Dividends.  Participants  who  receive
Shares  pursuant to the  Reinvestment  Plan as  described  above will  recognize
taxable  income in the amount of the fair market value of those  Shares.  In the
case of non-U.S.  participants  whose  Dividends are subject to U.S.  income tax
withholding  and in the case of any  participants  subject to 31% federal backup
withholding,  the Agent will reinvest  Dividends  after  deduction of the amount
required to be withheld.


The Fund  reserves  the right to amend or  terminate  the  Reinvestment  Plan by
written notice to participants.  All correspondence  concerning the Reinvestment
Plan should be  directed  to the Agent at the  address  referred to in the first
paragraph of this section.


                                       45
<PAGE>

                FEDERAL TAXATION OF THE FUND AND ITS SHAREHOLDERS

The following information is a brief, general summary for U.S. taxpayers. Please
see the SAI for additional  information.  Shareholders  should rely on their own
tax  advisors  for  advice  about the  particular  federal,  state and local tax
consequences of investing in the Fund.


The Fund  intends to operate so that it will not have to pay  federal  income or
excise tax. If the Fund were  required to pay federal  income or excise tax, its
investment performance would be adversely affected.


The Fund will distribute all or substantially  all of its net investment  income
and capital gains to its shareholders every year.  Shareholders will be taxed on
distributions  they  receive,  regardless  of  whether  they are paid in cash or
reinvested in Shares.  If the Fund declares a distribution in October,  November
or December of one year to  shareholders  of record in that year, but pays it in
January of the following year, shareholders will be taxed on the distribution as
if it was received on December 31 of the year in which it was declared.


The Fund will send shareholders a tax report each year, before February 1st. The
report will  designate the amount of dividends  that must be treated as ordinary
income  and  the  amount,   if  any,  that  must  be  treated  as  capital  gain
distributions.  If  the  Fund  designates  a  distribution  as  a  capital  gain
distribution,  shareholders will be required to pay tax thereon at the long-term
capital gains tax rate, no matter how long they held their Shares.


If a  shareholder  holds  Shares  in a  Retirement  Plan,  such as an  IRA,  the
shareholder  generally will not have to pay tax on Fund distributions until they
are distributed to the shareholder  from the Retirement  Plan.  Retirement Plans
are subject to complex tax rules,  and  shareholders  should  consult  their tax
advisors about investing in Shares through a Retirement Plan.

A  shareholder  generally  will have a capital gain or loss on a sale of Shares.
The amount of the gain or loss and the rate of tax will depend  primarily on how
much the shareholder paid for the Shares, how much the shareholder sold them for
and how long the Shares were held.


The Fund may be required to  withhold  federal  income tax at the rate of 31% of
all distributions  payable to an individual or other  non-corporate  shareholder
who fails to provide the Fund with a correct taxpayer  identification  number or
fails to make required  certifications,  or if the shareholder has been notified
by the IRS that he or she is subject to backup  withholding.  Backup withholding
is not an  additional  tax.  Any  amounts  withheld  may be  credited  against a
shareholder's federal income tax liability.


                  DESCRIPTION OF SHARES OF BENEFICIAL INTEREST

GENERAL

The Board of Trustees of the Fund has authority to issue an unlimited  number of
Shares,  $0.01 par value.  The Shares  outstanding are, and those offered hereby
when issued will be, fully paid and  nonassessable  by the Fund. The Shares have
no preemptive,  conversion,  exchange or redemption  rights.  Each Share has one
vote,  with  fractional  Shares  voting   proportionately.   Shares  are  freely
transferable,  and holders  thereof are entitled to dividends as declared by the
Board of Trustees. If the Fund were liquidated, shareholders would receive their
PRO-RATA  portion of its net assets.  Under the rules of the NYSE  applicable to
listed  companies,  the Fund  will be  required  to hold an  annual  meeting  of
shareholders in each year. If the Fund were converted to an open-end  investment
company or, if for any other reason the Shares are no longer  listed on the NYSE
(or any other  national  securities  exchange the rules of which require  annual

                                       46
<PAGE>

meetings of  shareholders),  the Fund does not intend to hold annual meetings of
shareholders.

Under  Massachusetts law,  shareholders could, under certain  circumstances,  be
held personally liable for the obligations of the Fund. However, the Declaration
of Trust disclaims shareholder liability for acts or obligations of the Fund and
requires that notice of such  disclaimer be given in each agreement  obligation,
or instrument entered into or executed by the Fund or the Board of Trustees. The
Declaration of Trust provides for  indemnification  out of Fund property for all
loss and expense of any shareholder  held personally  liable for the obligations
of the Fund. Thus, the risk of a shareholder incurring financial loss on account
of shareholder  liability is limited to circumstances in which the Fund would be
unable to meet its obligations. The likelihood of such circumstances is remote.

The Fund has no present  intention  of offering  additional  Shares,  other than
under this Offering and under the  Reinvestment  Plan.  See "Dividends and Other
Distributions; Dividend Reinvestment and Cash Purchase Plan." Other offerings of
Shares, if made, will require approval of the Board of Trustees.  Any additional
offering will be subject to the requirements of the 1940 Act that Shares may not
be sold at a price  below  the  then  current  NAV,  exclusive  of  underwriting
discounts and  commissions,  except in  connection  with an offering to existing
shareholders  or with the  consent of the  holders  of a majority  of the Fund's
outstanding  Shares.  In addition,  the Fund  expects  that it would  commence a
continuous  offering  of its  Shares in the event it  converted  to an  open-end
investment company. See "Conversion to Open-End Status."

The Declaration of Trust further  provides that  obligations of the Fund are not
binding  upon the Trustees  individually  but only upon the property of the Fund
and that the  Trustees  will not be liable for errors of judgment or mistakes of
fact or law, but nothing in the  Declaration of Trust protects a Trustee against
any  liability  to which the  Trustee  would  otherwise  be subject by reason of
willful  misfeasance,  bad faith,  gross negligence or reckless disregard of the
duties involved in the conduct of office.

CERTAIN ANTI-TAKEOVER PROVISIONS OF THE DECLARATION OF TRUST AND BY-LAWS

The Fund's Declaration of Trust and By-laws (together,  the "Charter Documents")
could have the effect of limiting:  (i) the ability of other entities or persons
to  acquire  control of the Fund;  (ii) the Fund's  freedom to engage in certain
transactions;  or  (iii)  the  ability  of  the  Fund's  Board  of  Trustees  or
shareholders  to amend the  Charter  Documents  or effect  changes in the Fund's
management.  Those  provisions  of the  Charter  Documents  may be  regarded  as
"anti-takeover"  provisions.  Commencing with the first meeting of shareholders,
the Board of Trustees  was  divided  into three  classes,  each having a term of
three years. At the annual meeting of shareholders in each year thereafter,  the
term of one class of Trustees expires.  Accordingly,  only those Trustees in one
class may be changed in any one year,  and up to three  years may be required to
replace a majority of the Board.  Such system of electing  Trustees may have the
effect of maintaining the continuity of management. Under the Fund's Declaration
of Trust,  the  affirmative  vote of the holders of not less than two-thirds (66
2/3%) of the Fund's outstanding Shares entitled to vote is required to authorize
the  consolidation of the Fund with another entity, a merger of the Fund with or
into  another  entity  (except  for  certain  mergers  in which  the Fund is the
successor), a sale or transfer of all or substantially all of the Fund's assets,
the  termination  of the  Fund,  the  conversion  of  the  Fund  to an  open-end
investment  company,  and any amendment to the Fund's  Declaration of Trust that
would affect any of the other provisions requiring a two-thirds vote. However, a
"Majority  Shareholder  Vote," as defined  in the  Charter  Documents,  shall be
sufficient  to  approve  any  of  the  foregoing  transactions  that  have  been
recommended by two-thirds of the Trustees.  Notwithstanding the foregoing,  if a
corporation, person or entity is directly, or indirectly through its affiliates,
the  beneficial  owner of more  than 5% of the  outstanding  Shares of the Fund,
("Principal Shareholder") the affirmative vote of 80% (which is higher than that

                                       47
<PAGE>

required under the 1940 Act) of the outstanding  Shares is required generally to
authorize any of the following  transactions  or to amend the  provisions of the
Declaration of Trust relating to transactions involving:

            (i)   a  merger or consolidation of the Fund with  or into any  such
            Principal Shareholder;

            (ii)  the  issuance  of  any  securities  of  the  Fund  to any such
            Principal Shareholder for cash;

            (iii) the sale, lease or exchange of all or any substantial part of
            the  assets of the Fund to any such  Principal  Shareholder  (except
            assets having an aggregate market value of less than $1,000,000);

            (iv)  the sale, lease or  exchange  to the  Fund,  in  exchange  for
            securities  of  the  Fund,  of any  assets  of  any  such  Principal
            Shareholder  (except assets having an aggregate fair market value of
            less than $1,000,000);

            (v)   the liquidation or termination of the Fund;

            (vi)  a change in the nature of the business  of the Fund so that it
            would cease to be an investment  company  registered under 1940 Act;
            or

            (vii) the conversion  of the Fund to an "open-end  company," or any
            amendment  to the  Declaration  of Trust of the Fund that  makes the
            Shares a  "redeemable  security,"  as such terms are  defined in the
            1940 Act.

If two-thirds of the Board has approved a memorandum of understanding  with such
beneficial  owner,  however,  a  majority  shareholder  vote,  as defined in the
Charter  Documents,  will be sufficient  to approve the foregoing  transactions.
Reference is made to the Charter  Documents  of the Fund,  on file with the SEC,
for the full text of these provisions.

The overall effect of the provisions of the Charter Documents described above is
to render more  difficult the  accomplishment  of a merger or the  assumption of
control by a shareholder  or another entity or person and to make the removal of
management  more  difficult  than if such  provisions  were not in place.  These
provisions  may be beneficial  to  management in a hostile  tender offer for the
Shares  and  may  have  an  adverse  impact  on  shareholders  who  may  want to
participate in such a tender offer. In particular, they could have the effect of
depriving shareholders of the opportunity to sell their Shares at a premium over
prevailing  market prices by  discouraging  a third party from seeking to obtain
control of the Fund in a tender offer or similar  transaction.  Moreover,  these
provisions would apply to actions proposed by anyone, including management,  and
would make changes in the Fund's  structure  accomplished  through a transaction
covered by the provisions more difficult to achieve. The provisions may give the
holders of a minority of the Shares  entitled to vote a veto power over a merger
that  management  and a  majority  of the  Fund's  shareholders  may  believe is
desirable and beneficial.

In the  opinion of the  Board,  however,  the  anti-takeover  provisions  of the
Charter Documents provide the advantage of potentially requiring persons seeking
control of the Fund to negotiate with its management  regarding price to be paid
and facilitating the continuity of the Fund's management,  investment  objective

                                       48
<PAGE>

and policies.  The Board has considered the foregoing  anti-takeover  provisions
and  concluded  that  they  are in  the  best  interests  of the  Fund  and  its
shareholders.  The above  description is subject to the provisions  contained in
the Charter Documents.

REPURCHASE OF SHARES

Shares of closed-end  funds  frequently trade at a discount from NAV but in some
cases trade at a premium.  In  recognition  of the  possibility  that the Shares
might similarly trade at a discount, the Fund's Board of Trustees has determined
that it would be in the interest of shareholders  for the Fund to take action to
attempt to reduce or  eliminate a market value  discount  from NAV. To that end,
the Board of  Trustees  recognizes  that the Fund might from  time-to-time  take
action either to  repurchase  its Shares in the open market or to tender for its
own Shares at NAV. The Board of Trustees,  in  consultation  with the Investment
Manager, reviews on a quarterly basis the possibility of open market repurchases
and/or  tender  offers for  Shares.  There are no  assurances  that the Board of
Trustees  will,  in fact,  decide to  undertake  either of these  actions or, if
undertaken, that such actions will result in the Shares trading at a price which
is equal to or approximates  their NAV. In addition,  the Board of Trustees will
not necessarily  announce when it has given consideration to these matters.  See
"Repurchase of Shares" in the SAI for further information.

CONVERSION TO OPEN-END STATUS

The Fund's  Declaration  of Trust provides that the Fund may be converted at any
time from a "closed-end  company" to an "open-end  company" upon the approval of
the holders of not less than two-thirds (66 2/3%) of the Shares  outstanding and
entitled to vote. If a corporation,  person or entity is directly, or indirectly
through its affiliates,  the beneficial owner of more than 5% of the outstanding
Shares,  the  affirmative  vote of 80% (which is higher than that required under
the  1940  Act) of the  outstanding  Shares  is  required  to  authorize  such a
conversion.  Shareholders  of an  open-end  investment  company  may require the
company to redeem their shares at any time (except in certain  circumstances  as
authorized by or under the 1940 Act) at their NAV, less  redemption  charge,  if
any, as might be in effect at the time of redemption.  The  Declaration of Trust
of the Fund provides that from time to time the Board will consider recommending
to the  shareholders  a proposal  to convert  the Fund from a  closed-end  to an
open-end  investment  company.  The Board may, however,  determine that the Fund
should not take any action to convert the Fund to an open-end investment company
or that, due to the characteristics of the Fund's portfolio  securities,  it may
be inappropriate to convert the Fund to an open-end investment company.

                       CUSTODIAN, TRANSFER AGENT, DIVIDEND
                         DISBURSING AGENT, AND REGISTRAR

The Fund's  securities  and cash are held under a custodian  agreement  by State
Street  Bank and  Trust  Company  ("State  Street"),  whose  principal  place of
business is 225 Franklin Street, Boston,  Massachusetts,  02110. With respect to
the Fund's  investments in Foreign  Securities,  the custodian  employs  foreign
subcustodians  approved by the Board of Trustees in accordance  with  applicable
regulations after  consideration of, among other things,  the  qualifications of
proposed foreign  subcustodians  and the legal  constraints  under which foreign
subcustodians operate. State Street also serves as transfer agent, registrar and
dividend disbursing agent for the Shares.  Pursuant to a services agreement with
EquiServe,  Inc., an affiliate of State Street,  serves as  Shareholder  Service
Agent  for the Fund  and,  as such,  performs  all of State  Street's  duties as
transfer agent and dividend-paying agent.


                                       49
<PAGE>

                                  LEGAL MATTERS

Kirkpatrick & Lockhart LLP, Washington,  D.C., serves as counsel to the Fund and
to the  Independent  Trustees and as special counsel to the Fund with respect to
the Offer and will pass on the legality of the Shares  offered  hereby.  Certain
legal matters will be passed on for the Dealer Manager by Skadden,  Arps, Slate,
Meagher & Flom (Illinois) and its affiliated entities.

                             REPORTS TO SHAREHOLDERS

The  Fund  will  send  unaudited  semi-annual  and  audited  annual  reports  to
shareholders, including a list of the portfolio investments held by the Fund.

                             INDEPENDENT ACCOUNTANTS

The data in the "Financial Highlights" section of this Prospectus are based upon
financial  statements  that have been  audited  by  PricewaterhouseCoopers  LLP,
independent accountants, as indicated in their reports with respect thereto, and
are included in reliance  upon the authority of said firm as experts in auditing
and accounting.

                               FURTHER INFORMATION

This  Prospectus  does  not  contain  all of the  information  set  forth in the
Registration  Statement  that the  Fund has  filed  with the SEC.  The  complete
Registration  Statement  may be  obtained  from the SEC upon  payment of the fee
prescribed by its Rules and Regulations.








                                       50
<PAGE>


            TABLE OF CONTENTS OF STATEMENT OF ADDITIONAL INFORMATION

ITEM No.   CAPTION                                               LOCATION IN SAI
- --------   -------                                               ---------------


14.        General Information                                          Page   3
15.        Additional Information About Its Investment                  Page   3
           Objective and Policies
16.        Investment Restrictions                                SEE PAGE 30 OF
                                                                  THE PROSPECTUS
17.        Management                                                    Page 11
18.        Ownership of Fund Shares                                      Page 18
19.        Portfolio Transactions                                        Page 18
20.        Repurchase of Shares and Tender Offers                        Page 19
21.        Taxation                                                      Page 21
22.        Financial Statements                                          Page 25








                                       51
<PAGE>

===================================   ==========================================


No one has been  authorized to give
any  information  or  to  make  any
representations  other  than  those
contained  in  this  Prospectus  in
connection   with  this  Offer.  If
other information is given or other
representations   are  made,   such
information or representations must
not be relied  upon  since  neither
was  authorized  by the  Fund,  the
Investment  Manager  or the  Dealer    7,539,029 SHARES OF BENEFICIAL INTEREST
Manager. This Prospectus  does  not
constitute  an offer to sell or the                 INVESCO GLOBAL
solicitation  of any  offer  to buy                     HEALTH
any  security other than the Fund's                  SCIENCES FUND
Shares,   as   described  in   this            ISSUABLE UPON EXERCISE OF
Prospectus.  This  Prospectus  also                      RIGHTS
also does not  constitute  an offer             TO SUBSCRIBE FOR SUCH
to sell  or a  solicitation  of any         SHARES OF BENEFICIAL INTEREST
buy the Fund's Shares, as described
in this  Prospectus,  by  anyone in
any  state  in  which  such   offer
or solicitation is not  authorized,
or in which the person  making such
offer  or   solicitation   is   not
qualified to do so,  or to any such
person  to whom it is   illegal  to
make  such  offer  or solicitation.
The  information in this Prospectus
may  no  longer  be  correct  after
after the  date on  the Prospectus.
However,  if  any  material  change
occurs during the period  in  which
this Prospectus is legally required             __________________________
to  be  delivered,  the  Prospectus
will  be  amended  or  supplemented                    PROSPECTUS
accordingly.                                    __________________________
      _____________________


         TABLE OF CONTENTS


                              Page                   DEALER MANAGER
                              ----
Prospectus Summary ..............1
Fee Table ......................10
Financial Highlights ...........12               PAINEWEBBER INCORPORATED
The Fund .......................16
Use of Proceeds ................28
Investment Objective and
 Policies ......................28
Risk Factors and Special
 Considerations ................34
Management of the Fund .........40                     May 24, 1999
Portfolio Trading ..............42                   FILE # 811-06476
Net Asset Value ................43
Dividends and Other Distributions:
  Dividend Reinvestment and
  Cash Purchase Plan ...........43
Federal Taxation Of The Fund And
  Its Shareholders..............45
Description of Shares of
  Beneficial Interest...........46
Custodian, Transfer Agent,
  Dividend Disbursing Agent,
  and Registrar ................49
Legal Matters ..................49
Independent Accountants ........49




===================================   ==========================================


                                       52
<PAGE>


                                  May 24, 1999.


[GRAPHIC OMITTED]




                       INVESCO GLOBAL HEALTH SCIENCES FUND

                       STATEMENT OF ADDITIONAL INFORMATION

This SAI is not a prospectus but should be read in  conjunction  with the Fund's
Prospectus  dated  [EFFECTIVE  DATE],  1999.  This  SAI  does  not  include  all
information  that a  prospective  investor  should  consider  before  purchasing
Shares,  and investors should obtain and read the Prospectus prior to purchasing
Shares. A copy of the Prospectus may be obtained without charge,  by calling the
Fund at 1-800-528-8765 or by contacting the Fund at 7800 E. Union Avenue,  Suite
800,  Denver,  Colorado  80237.  This SAI  incorporates  by reference the entire
Prospectus.

The  Prospectus  and this SAI omit certain of the  information  contained in the
registration  statement  filed by the Fund with the SEC,  Washington,  D.C. That
registration  statement  may be  obtained  from the SEC upon  payment of the fee
prescribed or inspected at the SEC's office at no charge.  Capitalized terms not
defined herein have the meanings attributed to them in the Prospectus.

INFORMATION   CONTAINED  HEREIN  IS  SUBJECT  TO  COMPLETION  OR  AMENDMENT.   A
REGISTRATION STATEMENT RELATING TO THESE SECURITIES HAS BEEN FILED WITH THE SEC.
THESE  SECURITIES MAY NOT BE SOLD NOR MAY ANY OFFERS TO BUY BE ACCEPTED PRIOR TO
THE TIME  THE  REGISTRATION  STATEMENT  BECOMES  EFFECTIVE.  THIS  STATEMENT  OF
ADDITIONAL INFORMATION DOES NOT CONSTITUTE A PROSPECTUS.



<PAGE>


            TABLE OF CONTENTS OF STATEMENT OF ADDITIONAL INFORMATION

ITEM No.   CAPTION                                               LOCATION IN SAI
- --------   -------                                               ---------------


14.        General Information                                          Page   3
15.        Additional Information About Its Investment                  Page   3
           Objective and Policies
16.        Investment Restrictions                                SEE PAGE 30 OF
                                                                  THE PROSPECTUS
17.        Management                                                    Page 11
18.        Ownership of Fund Shares                                      Page 18
19.        Portfolio Transactions                                        Page 18
20.        Repurchase of Shares and Tender Offers                        Page 19
21.        Taxation                                                      Page 21
22.        Financial Statements                                          Page 25












                                       2
<PAGE>

                               GENERAL INFORMATION

INVESCO  Global Health  Sciences Fund is a  diversified,  closed-end  management
investment  company under the  Investment  Company Act of 1940, as amended.  The
Fund's investment manager is INVESCO Funds Group, Inc.

                   ADDITIONAL INFORMATION ABOUT ITS INVESTMENT
                             OBJECTIVE AND POLICIES

The Fund's  investment  objective is to seek capital  appreciation  by investing
substantially  all of its assets in equity and related  securities  of U.S.  and
foreign Health Science Companies.  The Fund is aggressively  managed for growth.
The Fund seeks to achieve its objective by investing its assets in a broad range
of health care related equity securities, such as market-leading  pharmaceutical
companies,  medical  devices  manufacturers  and suppliers,  and various private
placement investments.

Some of the different types of securities in which the Fund may invest,  subject
to its investment objective,  policies,  and restrictions,  are described in the
Prospectus  under  "Investment  Objective and Policies" and "Special  Investment
Practices."  Additional information concerning certain of the Fund's investments
and investment techniques is set forth below.

HEDGING -FUTURES AND OPTIONS TRANSACTIONS

GENERAL.  The Fund may engage in futures and options  transactions in accordance
with its investment  objective and policies.  The Fund intends to engage in such
transactions if it appears  advantageous  to the Investment  Manager to do so in
order to pursue its investment objective, to hedge against the effects of market
conditions  and to  stabilize  the value of its  assets.  The use of futures and
options,  possible benefits and attendant risks are discussed below,  along with
information concerning certain other investment policies and techniques.

OPTIONS ON SECURITIES.  The Fund is authorized to write covered call options and
secured put options and to purchase  put and call options on the  securities  in
which it may invest that are listed on domestic  exchanges  or on the  quotation
system operated by the National Association of Securities Dealers, Inc. ("listed
options"),  or that are privately  negotiated in  over-the-counter  transactions
("OTC  options").  OTC  options,  other than those  discussed  in the  following
sentence,  are deemed to be illiquid securities and are,  therefore,  subject to
the Fund's  limitation that a maximum of 25% of its total assets may be invested
in illiquid securities.  The Fund may engage in OTC options transactions on U.S.
Government  Securities with U.S. Government Securities dealers recognized by the
Federal  Reserve Bank of New York  subject to a forward  price at which the Fund
has the absolute  right to repurchase the OTC option which it has sold, in which
case the value of such OTC option purchased will not be considered illiquid.  In
OTC  options  transactions  with other  dealers or without  such  pre-negotiated
forward  repurchase  prices,  OTC options  purchased and the Fund assets used to
"cover" OTC options sold by the Fund will be  considered  "illiquid  securities"
and will be subject to the Fund's  limitation that a maximum of 25% of its total
assets may be  invested  in  illiquid  securities.  The  "formula"  on which the
forward  price will be based may vary among  contracts  with  different  primary
dealers,  although  generally  it will be based  on a  multiple  of the  premium
received by the Fund for  writing  the option  plus the  amount,  if any, of the
option's   intrinsic  value,  I.E.,  current  market  value  of  the  underlying
securities  minus the  option's  strike  price.  Listed  options are issued by a
clearing corporation, the Options Clearing Corporation ("OCC").

By purchasing a listed call option on a security, the Fund will obtain the right
to buy the securities underlying the option from the OCC at a specified exercise
price prior to or at the expiration of the option.  By selling (writing) such an


                                       3
<PAGE>

option,  the Fund will obligate  itself to sell the  securities  underlying  the
option to the OCC at the specified  exercise price prior to or at the expiration
if it is  assigned  an  exercise  notice.  A listed  put  option  on a  security
purchased by the Fund gives the Fund the right to sell the securities underlying
the option to the OCC at the exercise  price prior to or at the  expiration.  By
selling  (writing)  such  an  option,  the  Fund  obligates  itself  to buy  the
securities  underlying the option from the OCC at the exercise price prior to or
at the expiration if it is assigned an exercise notice.

OTC options operate in a similar manner but are purchased from or sold (written)
to dealers or financial institutions which enter into direct agreements with the
Fund. While listed options have "standardized" exercise prices, expiration dates
and other  features,  the features of OTC options can vary as agreed upon by the
Fund and by the other party to the option and there is no  intermediation of the
OCC.

The Fund may purchase call options to protect against  increases in the costs of
securities proposed to be acquired or to terminate ("close out") existing option
positions.  Put options may be purchased to seek to protect against  declines in
the  value of  securities  which  are held (or  which  the Fund has the right to
acquire) or to close out existing  option  positions.  When put and call options
are sold (written) by the Fund, the Fund receives  premiums as the writer of the
options,  which provide a partial hedge against adverse  movements in the prices
of the underlying  securities.  The income received from premiums will fluctuate
with varying economic market conditions.  Calls may also be written to close out
existing  option  positions.  Put options  may also be sold when the  Investment
Manager  wishes to purchase a security at a price lower than its current  market
price.  Call  options  written by the Fund must be  "covered."  A call option is
covered if the Fund owns or has the right to acquire the  securities  underlying
the option.  A call option is also  covered if the Fund holds a call on the same
security as the underlying  security of the written  option,  where the exercise
price of the call used for coverage is equal to or less than the exercise  price
of the call written or, if the  exercise  price of the call used for coverage is
greater than the exercise price of the call written,  by maintaining the mark to
market  difference in cash,  U.S.  Government  Securities or other liquid,  high
quality  short-term  debt  obligations  in a segregated  account with the Fund's
custodian.

In the  case of  listed  options  and  certain  OTC  options,  during  or at the
termination  of the option  period,  the Fund may be required,  at any time,  to
deliver the  underlying  security  against  payment of the exercise price on any
calls it has written.  Exercise of certain listed options and OTC options may be
limited to  specific  expiration  dates.  This  obligation  terminates  upon the
expiration of the option period.  The obligation can be terminated at an earlier
time by effecting a closing purchase transaction. A closing purchase transaction
is  accomplished  by  purchasing  an  option of the same  series  as the  option
previously written.  However, once assigned an exercise notice with respect to a
listed option, the Fund will be unable to effect a closing purchase transaction.

Closing purchases transactions are ordinarily effected to realize a profit on an
outstanding call option, to prevent an underlying security from being called, to
permit the sale of an  underlying  security or to enable  another call option on
the underlying  security  (with either a different  exercise price or expiration
date or both) to be written. Also, effecting a closing purchase transaction will
permit the cash or proceeds from the concurrent  sale of any securities  subject
to the option to be used for other investments.  The Fund may realize a net gain
or loss from a closing purchase transaction depending upon whether the amount of
the  premium  received  on the  call  option  is more or less  than  the cost of
effecting  the  closing  purchase  transaction.  Any loss  incurred in a closing
purchasing   transaction  may  be  wholly  or  partially  offset  by  unrealized
appreciation in the market value of the underlying security.  Conversely, a gain
resulting  from a closing  purchase  transaction  could be offset in whole or in
part or exceeded by a decline in the market value of the underlying security.


                                       4
<PAGE>

If a call option  written by the Fund expires  unexercised,  the Fund realizes a
gain in the amount of the premium on the option less the commission paid. Such a
gain,  however,  may be  offset  by  depreciation  in the  market  value  of the
underlying  security  during the option period.  If a call option written by the
Fund is  exercised,  it realizes a gain or loss from the sale of the  underlying
security  equal to the  difference  between the purchase price of the underlying
security and the proceeds of the sale of the security plus the premium  received
on the option less the commission paid.

Options written by the Fund normally have expiration  dates of up to nine months
from the date written.  The exercise price of a call option may be below,  equal
to or above the current market value of the underlying  security at the time the
option is written.

As a writer of a secured put option on securities, the Fund incurs an obligation
to buy the security  underlying the option from the purchaser of the put, at the
option's  exercise price at any time during, or at the expiration of, the option
period (certain listed and OTC put-options  will be exercisable by the purchaser
only on a specific  date).  A put is  "secured" if the Fund  maintains  with its
custodian in a segregated  account  cash,  U.S.  Government  Securities or other
liquid,  high quality short-term debt obligations in an amount equal to at least
the exercise price of the option.  Similarly, a put position could be covered by
purchase of a put option on the same  underlying  security,  where the  exercise
price of the option purchased is equal to or more than the exercise price of the
put  written or less than the  exercise  price of the put written if the mark to
market  difference is maintained in cash. In writing puts,  the Fund assumes the
risk of loss should the market value of the  underlying  security  decline below
the exercise price of the option (any loss being decreased by the receipt of the
premium on the option written).  The operation of and limitations on secured put
options in other respects are substantially identical to those of call options.

The Fund will  write put  options to obtain  income  from the  premiums  paid by
purchasers which provide a partial hedge. Puts may also be written when the Fund
wishes to purchase  securities at prices lower than their current market prices,
in which case the Fund will write the put at an exercise  price  reflecting  the
lower  purchase  price  sought.  The  potential  gain on a secured put option is
limited to the premium  received on the option (less the commissions paid on the
transaction) while the potential loss equals the difference between the exercise
price of the option and the current market price of the underlying securities at
the  time  the put is  exercised,  offset  by the  premium  received  (less  the
commissions  paid on the  transaction).  Puts may also be  written  to close out
existing option positions.

The Fund may purchase put options on securities which it holds (or has the right
to acquire) to protect against a decline in the value of its securities.  If the
value  of the  underlying  securities  were in such a case  to  fall  below  the
exercise  price of the put purchased in an amount  greater than the premium paid
for the  option,  the Fund would  incur no  additional  loss.  The Fund may also
purchase put options to close out written put  positions in a manner  similar to
call options closing  purchase  transactions.  Such a sale would result in a net
gain or loss  depending  on whether  the amount  received on the sale is more or
less than the premium and other  transaction  costs paid on the put option which
is sold.  If a put option  purchased by the Fund expires  without  being sold or
exercised, the premium will be lost.

During the option  period,  a covered call writer has, in return for the premium
on the  option,  given up the  opportunity  for capital  appreciation  above the
exercise price should the market price of the underlying security increase,  but
has  retained  the risk of loss  should  the  price of the  underlying  security
decline.  A secured put writer  also  retains the risk of loss should the market
value of the underlying  security decline below the exercise price of the option
less the premium  received on the sale of the option.  In both cases, the writer
has no control  over the  exercise  of the option and may be required to fulfill
its obligation as a writer of the option.  Once an option writer has received an
exercise  notice with  respect to a listed  option,  it cannot  effect a closing


                                       5
<PAGE>

purchase  transaction in order to terminate its obligation  under the option and
must deliver or receive the underlying securities at the exercise price.

Prior to exercise or  expiration,  an option  position can only be terminated by
entering into a closing purchase or sale  transaction.  If a covered call option
writer is unable to effect a closing transaction or enter into an offsetting OTC
option,  it cannot sell the underlying  security until the option expires or the
option  is  exercised  or the Fund  provides  an  alternative  means  of  cover.
Accordingly,  a covered call option writer may not be able to sell an underlying
security at a time when it might  otherwise be  advantageous to do so. A secured
put option writer who is unable to effect a closing transaction or an offsetting
OTC option would continue to bear the risk of decline in the market price of the
underlying security until the option expires or is exercised. In addition, a put
writer would be unable to utilize the amounts  securing the put option until the
exercise or expiration of the option.

The  Fund's  ability  to close  out its  position  as a writer  of an  option is
dependent upon the existence of a liquid secondary market. There is no assurance
that such a market will exist,  particularly in the case of OTC options, as such
options will generally only be closed out by entering into a closing transaction
with a dealer.  However, the Fund may be able to purchase or write an offsetting
option  which does not close out its  position  as a writer but  constitutes  an
asset  offsetting the risks of the obligation  under the option written.  If the
Fund is not able to enter into a closing transaction or an offsetting  position,
it will be required  to  maintain  the  securities  subject to the call,  or the
collateral  underlying the put, even though it might not be  advantageous  to do
so, until a closing  transaction can be entered into (or the option is exercised
or expires).

The  possible  reasons for the absence of a liquid  secondary  market for listed
options  include:  (i) insufficient  trading  interest in certain options;  (ii)
restrictions  on  transactions  imposed  by  exchanges;   (iii)  trading  halts,
suspensions or other restrictions  imposed with respect to particular classes or
series of options or  underlying  securities;  (iv)  interruption  of the normal
operations on an exchange;  (v)  inadequacy of the  facilities of an exchange or
the OCC to handle  current  trading  volume;  or (vi) a decision  by one or more
exchanges to discontinue the trading of options (or a particular class or series
of options),  in which event the  secondary  market on that exchange (or in that
class or series of options) would cease to exist,  although  outstanding options
on that  exchange  that had been issued by the OCC as a result of trades on that
exchange would  generally  continue to be  exercisable in accordance  with their
terms.  The inability to close out options  positions could also have an adverse
impact on the ability of the Fund to hedge its  positions.  In addition,  in the
event of the  bankruptcy  of a broker  through which the Fund engages in options
transactions, particularly a broker who sold an OTC option to the Fund, the Fund
could  experience  delays or losses in liquidating  open positions  purchased or
sold through such brokers or loss of all or part of the value of the options. It
should  also be noted that  exchanges  have  limitations  governing  the maximum
number of options of a particular type that may be written by a single investor.
Positions in excess of these limitations may be required to be liquidated. These
positions  limits may  operate  to  restrict  the number of options  that may be
written by the Fund.

The hours of trading for options may not conform to the hours  during  which the
underlying  securities  are traded.  To the extent that the option markets close
before the markets for the  underlying  securities,  significant  price and rate
movements can take place in the  underlying  markets that cannot be reflected in
the option markets.

STOCK INDEX  OPTIONS.  The Fund may purchase  and sell (write)  options on stock
indices  ("index  options").  These options are similar to options on securities
except that, rather than taking or making delivery of securities  underlying the
option at a specified price upon exercise,  an index option gives the holder the
right to  receive  cash upon  exercise  of the  option if the level of the stock
index  upon  which the  option is based is  greater,  in the case of a call,  or


                                       6
<PAGE>

lesser,  in  the  case  of a  put,  than  the  exercise  price  of  the  option.
Transactions  in index options will be effected to hedge  against  adverse price
movements in the stock market generally or in particular market segments.

Options  on stock  indices  provide  the Fund with a means of seeking to protect
against  the risk of market  wide price  movements.  If the  Investment  Manager
anticipates a market decline,  the Fund could purchase a stock index put option.
If the expected market decline materialized, the resulting decrease in the value
of the Fund's  securities  would be offset to the extent of the  increase in the
value of the put option.  If the Investment  Manager  anticipates a market rise,
the  Fund  may  purchase  a stock  index  call  option  to  enable  the  Fund to
participate  in such rise  until  completion  of  anticipated  stock  purchases.
Purchases and sales of stock index options also enable the Investment Manager to
more efficiently achieve changes in equity positions.

Stock index options  involve risks similar to those  associated  with options on
securities.  However,  because  exercise of stock  index  options are settled in
cash,  call  writers  such as the Fund  cannot  provide  in  advance  for  their
potential  settlement  obligations  by  acquiring  and  holding  the  underlying
securities.  A call write can offset some of the risk of its writing position by
holding  a  diversified  portfolio  of  stocks  similar  to those  on which  the
underlying  index is based.  However,  most  investors  cannot,  as a  practical
matter,  acquire and hold a portfolio  containing exactly the same stocks as the
underlying index and, as a result,  bear a risk that the value of the securities
held  will  vary  from the value of the  index.  For a  discussion  of the risks
associated  with imperfect  correlation of the stock index and the securities in
the Fund's portfolio, see "Investment Objective and Policies--Special Investment
Practices--Hedging."  Even if an index call  writer  could  assemble a portfolio
that exactly  replicated the  composition of the  underlying  index,  the writer
still would not be fully covered from a risk  standpoint  because of the "timing
risk" inherent in writing index options.  When a index option is exercised,  the
amount of cash that the  holder is  entitled  to receive  is  determined  by the
difference  between the exercise  price and the closing  index level on the date
when the option is exercised.  As with other kinds of listed options, the writer
will not learn  that it has been  assigned  an  exercise  notice  until the next
Business Day, at the  earliest.  By the time it learns that it has been assigned
an exercise notice, the index may have declined,  with a corresponding  decrease
in the  value  of  its  stock  portfolio.  This  "timing  risk"  is an  inherent
limitation  on the ability of index call writers to cover their risk exposure by
holding stock positions.  In addition, a holder of an index option who exercises
it before the closing  index value for that day is available  runs the risk that
the level of the  underlying  index may  subsequently  change.  If such a change
causes  the  exercise  price of the option to exceed  the  current  value of the
underlying  securities at the time the option is written,  the exercising holder
will be required to pay the  difference  between the closing index value and the
exercise price of the option (times the  applicable  multiplier) to the assigned
writer.

If dissemination of the current level of an underlying index is interrupted,  or
if trading is interrupted in stocks  accounting for a substantial  percentage of
the value of an index,  the trading of options on that index will  ordinarily be
halted.  If the trading of options on an  underlying  index is halted,  the Fund
would not be able to close out positions and an exchange may impose restrictions
prohibiting the exercise of such options.  If trading in options on the index is
not halted,  the prices of the options may be  distorted.  These  results  could
result in losses to the Fund. It should also be recognized  that the markets for
certain stock index options may be relatively  illiquid,  which could impair the
ability of the Fund to close out positions on such options.


FUTURES  CONTRACTS.  The Fund may enter into  contracts for the purchase or sale
for future  delivery  of baskets of  securities,  financial  indices,  financial
instruments or foreign currencies.  The Fund will not purchase or sell a futures
contract or purchase an option on a futures contract if, immediately thereafter,
the sum of the amount of initial margin deposits on the Fund's existing  futures
positions,  and premiums  paid on options on futures  contracts  which are still



                                       7
<PAGE>

outstanding  and which do not constitute bona fide hedging  transactions,  would
exceed 5% of the value of the Fund's assets.  U.S.  futures  contracts have been
designed by  exchanges  which have been  designated  "contracts  markets" by the
Commodity  Futures  Trading  Commission  and must be  executed  on the  relevant
contract market.  Futures contracts trade on a number of exchange markets,  and,
through their clearing corporations,  the exchanges guarantee performance of the
contracts as between the clearing members of the exchange.

At the same time a futures contract is purchased or sold, the Fund must allocate
cash or securities as a good faith deposit payment  ("initial margin  deposit").
It is expected that the initial  deposit would be  approximately  5% to 15% of a
contract's face value.  Thereafter,  the Fund must make additional deposits with
the applicable financial intermediary, and will be credited with an amount equal
to any net gains due to favorable price movements.  These additional deposits or
credits are calculated  and required daily and are known as "variation  margin."
The amount of the initial  margin  deposit  required  for a  particular  futures
contract  may be revised  from time to time by the  applicable  exchange  as the
volatility of the contract fluctuates.

Futures  contracts by their terms call for delivery of the underlying  financial
instruments  or,  in the case of index  contracts,  for cash  settlement  at the
delivery  date  of  the  contract.  In  most  cases,  however,  the  contractual
obligation  is  fulfilled  before  the date of  delivery  under the terms of the
contract  through  offset.  The  offsetting  of  a  contractual   obligation  is
accomplished  by  buying  (or  selling,  as the  case  may be) on a  commodities
exchange an identical  futures  contract calling for delivery in the same month.
Such a transaction,  which is effected through a member of an exchange,  cancels
the obligation to make or take delivery  under the terms of the contract.  Since
all transactions in the futures market are made,  offset or fulfilled  through a
clearing house  associated  with the exchange on which the contracts are traded,
the Fund will incur brokerage fees when it purchases or sells futures contracts.

The purpose of the  acquisition  or sale of a futures  contract is to attempt to
protect the Fund from  fluctuations  in the value of the securities  held by the
Fund.  For  example,  if the Fund owns equity  securities  which are expected to
decline in value  temporarily,  the Fund might enter into futures  contracts for
the sale of an index of equity securities. If the Fund's portfolio and the index
tended to  fluctuate  in common,  such a sale would have much the same effect as
selling  an  equivalent  value  of the  securities  owned  by the  Fund.  If the
securities in the portfolio  declined as expected,  the futures contracts to the
Fund would increase at  approximately  the same rate,  thereby  keeping the next
asset value of the Fund from  declining as much as it otherwise  would have. The
Fund could accomplish similar results by selling its securities.  However, since
the  futures  market is more  liquid  than the cash  market,  the use of futures
contracts  as an  investment  technique  allows the Fund to maintain a defensive
position without having to sell its portfolio  securities.  The Fund's portfolio
and the index  will not  necessarily  fluctuate  in  common.  The Fund bears the
additional  risk  that  any  divergence  resulting  from  the  Fund's  portfolio
appreciating  or depreciating  more or less than the index operates  unfavorably
toward the Fund, resulting in a correlation risk similar to that discussed under
"Investment Objective and Policies--Special Investment Practices--Hedging."

Similarly,  when the Fund has a quantity of short  positions in securities  that
are expected to increase in value  temporarily,  or anticipates  the purchase of
such securities,  futures contracts may be purchased to attempt to hedge against
anticipated  losses to the Fund. To the extent that the  fluctuations in futures
contracts  are similar to that of the Fund's short  positions or the  securities
the Fund anticipates acquiring, the Fund could take advantage of the anticipated
rise in value without actually buying the securities.

To the extent the Fund has a short position in a futures contract,  the Fund may
cover by holding the  instruments  or currency  underlying  the  contract or may
maintain  assets in a segregated  account to cover the Fund's  obligations  with


                                       8
<PAGE>

respect to such  futures  contracts.  The assets in such account will consist of
cash, cash equivalents or high quality debt securities in an amount equal to the
difference  between the fluctuating  market value of such futures  contracts and
the  aggregate  value of the initial and variation  margin  payments made by the
Fund with respect to such futures contracts.

The ordinary  spreads  between  prices in the cash and futures  markets,  due to
differences in the nature of those markets,  are subject to distortions.  First,
all  participants  in the  futures  market are  subject to initial  deposit  and
variation margin  requirements.  Rather than meeting additional variation margin
requirements,   investors  may  close  futures  contracts   through   offsetting
transactions  which could distort the normal  relationship  between the cash and
futures  markets.  Second,  the  liquidity  of the  futures  market  depends  on
participants entering into offsetting  transactions rather than making or taking
delivery. To the extent participants decide to make or take delivery,  liquidity
in the future market could be reduced,  thus producing  distortion.  Third, from
the point of view of speculators, the margin deposit requirements in the futures
market are less  onerous  than margin  requirements  in the  securities  market.
Therefore,  increased  participation  by  speculators  in the futures market may
cause  temporary  price  distortions.  Due to the  possibility of distortion,  a
correct  forecast of price  movements  by the  Investment  Manager may still not
result in a successful transaction.

In addition,  futures  contracts entail risks.  Although the Investment  Manager
will only enter into futures contracts if it believes that use of such contracts
will benefit the Fund, if the Investment Manager's investment judgment about the
general  direction of  securities or currency  prices is  incorrect,  the Fund's
overall  performance  would be poorer than if it had not  entered  into any such
contract.  For  example,  if the Fund has hedged  against the  possibility  of a
decline in securities  prices and prices  increase  instead,  the Fund will lose
part or all of the benefit of the increased  value of the securities that it has
hedged  because it will have  offsetting  losses in its  futures  positions.  In
addition, in such situations,  if the Fund has insufficient cash, it may have to
sell securities from its portfolio to meet daily variation margin  requirements.
Such sales of  securities  may be,  but will not  necessarily  be, at  increased
prices which reflect the rising market.  The Fund may have to sell securities at
a time when it may be disadvantageous to do so.

Exchanges may limit the amount by which the price of many futures  contracts may
move on any day. If the price moves equal to the daily limit on successive  days
then it may prove  impossible  to liquidate a futures  position  until the daily
limit moves have ceased.

OPTIONS ON FUTURES  CONTRACTS.  The Fund is  authorized  to  purchase  and write
options on futures contracts for hedging purposes. The purchase of a call option
on a futures  contract  is similar in some  respects  to the  purchase of a call
option on an individual  security.  Upon the exercise of a call option, the Fund
receives a long position in the underlying  futures  contract.  Depending on the
pricing of the option compared to either the price of the futures  contract upon
which it is based or the price of the underlying financial  instruments,  it may
or may not be less risky than  ownership  of the futures  contract.  As with the
purchase  of  futures  contracts,  when the Fund is not  fully  invested  it may
purchase a call option on a futures  contract to hedge against a market  advance
in which it would not otherwise  participate.  The purchase of a put option on a
futures  contract is similar in some respects to the purchase of protective  put
options  on  portfolio  securities.  Upon  exercise  of a put  option,  the Fund
receives a short position in the underlying futures contract.  For example,  the
Fund may  purchase  a put  option on a  futures  contract  to hedge  the  Fund's
portfolio against the risk of declining securities values.

The writing of a call option on a futures  contract  constitutes a partial hedge
against  declining  prices of the  components  of the futures  contract.  If the
futures price at expiration of the call option is below the exercise price,  the
Fund will retain the full amount of the option  premium that  provides a partial
hedge  against  any  decline  that may have  occurred  in the  Fund's  portfolio


                                       9
<PAGE>

holdings.  The  writing  of a put  option on a futures  contract  constitutes  a
partial hedge against  increasing  prices of the  financial  instrument  that is
deliverable  upon termination of the futures  contract.  If the futures price at
expiration  of the put option is higher than the exercise  price,  the Fund will
retain  the full  amount of the option  premium  that  provides a partial  hedge
against  any  increase  in the  price of  securities  that the Fund  intends  to
purchase.  If a put or call option the Fund has written is  exercised,  the Fund
will incur a loss that will be reduced by the amount of the premium it receives.
Depending  on the  degree  of  correlation  between  changes  in  its  portfolio
securities and changes in its futures positions, the Fund's losses from existing
options  may to some  extent be reduced  or  increased  by changes in  portfolio
securities.

The amount of risk the Fund  assumes  when it  purchased  an option on a futures
contract is the premium paid for the option plus related  transaction  costs. In
addition to the  correlation  risks discussed  above,  the purchase of an option
also entails the risk that changes in the underlying  futures  contract will not
be fully reflected in the option purchased.

The Fund's  ability to engage in the options and  futures  strategies  described
above will depend on the availability of liquid markets in such instruments.  It
is  impossible  to  predict  the amount of  trading  interest  that may exist in
various  types of options or futures.  Therefore no assurance  can be given that
the Fund will be able to utilize these instruments  effectively for the purposes
set forth  above.  Furthermore,  the Fund's  ability  to engage in  options  and
futures transactions may be limited by tax considerations.

FOREIGN MARKET  TRANSACTIONS.  In addition,  options on  securities,  options on
indices,  futures  contracts,  and options on futures contracts may be traded on
foreign  exchanges.  Such  transactions  are subject to the risk of governmental
actions affecting trading in or the prices of such options or futures contracts.
Such positions also could be adversely  affected by: (i) other complex  foreign,
political,  and economic  factors;  (ii) lesser  availability than in the United
States of data on which to make  trading  decisions;  (iii) delays in the Fund's
ability  to act  upon  economic  events  occurring  in  foreign  markets  during
non-business  hours in the  United  States;  (iv) the  imposition  of  different
exercise and settlement terms and procedures and margin requirements than in the
United States; and (v) lesser trading volume.


FORWARD CONTRACTS. The Fund may enter into forward contracts to purchase or sell
foreign  currencies as a hedge against  possible  variations in foreign exchange
rates.  A  forward  foreign  currency  contract  is  an  agreement  between  the
contracting  parties to exchange an amount of currency at some future time at an
agreed upon rate. The rate can be higher or lower than the spot rate between the
currencies that are the subject of the contract.  A forward  contract  generally
has no deposit requirement, and such transactions do not involve commissions. By
entering  into a forward  contract  for the  purchase  or sale of the  amount of
foreign  currency  invested in a Foreign  Securities  transaction,  the Fund can
hedge against  possible  variations  in the dollar  versus the subject  currency
either  between the date the Foreign  Security is purchased or sold and the date
on which payment is made or received  during the time the Fund holds the Foreign
Security. The Fund will not speculate in forward currency contracts. If the Fund
enters  into a sale of forward  foreign  currency  with  respect to a  portfolio
security  denominated  in such foreign  currency,  its custodian bank will place
cash or liquid equity or debt securities in a separate account of the Fund in an
amount equal to the Fund's total assets  committed to the  consummation  of such
forward contract.  If the securities placed in the account declines,  additional
cash or securities  will be placed in the account so that the account will equal
the amount of the Fund's  commitment  with respect to such  contracts.  The Fund
will purchase or sell  currency  futures or options on such futures for the same
reasons as set forth above for entering into forward foreign currency contracts.
The Fund does not  anticipate  attempting to hedge all of its foreign  portfolio
positions  and will enter into such  transactions  only to the  extent,  if any,



                                       10
<PAGE>

deemed  appropriate  by the Investment  Manager.  The Fund will not enter into a
forward contract for a term of more than one year.

FUTURE  DEVELOPMENTS.  The Fund may,  following  written  notice  thereof to its
shareholders,  take advantage of opportunities  in the area of options,  futures
contracts,  options on futures contracts,  and other derivative instruments that
are not  currently  contemplated  for use by the Fund or that are not  currently
available but that may be developed,  to the extent such  opportunities are both
consistent with the Fund's investment  objective and legally permissible for the
Fund.  Such  opportunities,  if they arise,  may involve risks that exceed those
involved in the options and futures activities described above.

REGULATORY  RESTRICTIONS.  To the extent required to comply with SEC Release No.
10666, when purchasing a futures contract or writing a put option, the Fund will
maintain,  in a segregated account, cash or liquid securities equal to the value
of such contracts.

The Fund will typically enter into a futures  contract or related option only if
it  constitutes  a bona fide  hedging  position  under  applicable  regulations.
Otherwise the Fund will limit its  investments in futures  contracts and related
options so that, immediately after such investment, the sum of the amount of its
initial  margin  deposits on open  futures  contracts  and its  premiums on open
options  contracts  will not  exceed 5% of the  Fund's  total  assets at current
value.

ACCOUNTING  AND TAX  CONSIDERATIONS.  When the Fund writes an option,  an amount
equal to the premium it receives  is  included  in its  Statement  of Assets and
Liabilities as a liability.  The amount of the liability is subsequently  marked
to market to reflect  the  current  market  value of the  option.  When the Fund
purchases  an  option,  the  premium  it pays is  recorded  as an  asset  and is
subsequently adjusted to the current market value of the option.

In the case of a regulated  futures  contract  purchased or sold by the Fund, an
amount equal to the initial margin  deposit is recorded as an asset.  The amount
of the asset is  subsequently  adjusted to reflect  changes in the amount of the
deposit as well as changes in the value of the contract.

For a discussion of the tax treatment of investments in certain options, futures
and foreign currency contracts, see "Taxation" below.

                                   MANAGEMENT

INVESTMENT MANAGEMENT AGREEMENT

The Investment  Management  Agreement  provides that the Investment Manager will
provide  portfolio   management  services,   place  portfolio   transactions  in
accordance with policies expressed in the Fund's registration statement, pay the
Fund's office rent, and render significant  administrative services on behalf of
the Fund (not  otherwise  provided by third  parties)  necessary  for the Fund's
operation  as a  closed-end  fund,  including  preparing  reports to and meeting
materials  for the Fund's  Board of  Trustees  and  reports  and notices to Fund
shareholders;  supervising,  negotiating  contractual  arrangements with, to the
extent  appropriate,  and monitoring the performance of various  third-party and
affiliated  service  providers  to the Fund  (such as the  Fund's  transfer  and
pricing  agents,  custodian,  accountants  and others) and other  persons in any
capacity deemed necessary or desirable to Fund operations;  preparing and making
filings with the SEC and other  regulatory  and  self-regulatory  organizations,
including preliminary and definitive proxy materials,  post-effective amendments
to the Registration Statement and semi-annual reports on Form N-SAR;  overseeing
the  tabulation  of proxies  by the  Fund's  transfer  agent;  assisting  in the
preparation  and  filing of the  Fund's  federal,  state and local tax  returns;
preparing and filing the Fund's federal excise tax returns; providing assistance


                                       11
<PAGE>

with  investor  and  public  relations  matters;  monitoring  the  valuation  of
portfolio  securities and the calculation of NAV; monitoring the registration of
Shares  under  applicable  federal and state  securities  laws;  maintaining  or
causing to be  maintained  for the Fund all books,  records  and reports and any
other information required under the 1940 Act, to the extent such books, records
and reports and other  information are not maintained by the Fund's custodian or
other agents of the Fund;  assisting in establishing  accounting policies of the
Fund;  assisting  in the  resolution  of  accounting  issues that may arise with
respect to the Fund's  operations  and  consulting  with the Fund's  independent
accountants,   legal  counsel  and  other  agents  as  necessary  in  connection
therewith;  establishing  and monitoring the Fund's  operating  expense budgets;
reviewing  the  Fund's  bills;  processing  the  payment of bills that have been
approved by an authorized  person;  assisting the Fund in determining the amount
of  dividends  and other  distributions  available to be paid by the Fund to its
shareholders,  preparing and  arranging for the printing of dividend  notices to
shareholders,  and  providing  the  transfer  and  dividend  paying  agent,  the
custodian,  and the  accounting  agent with such  information as is required for
such parties to effect the payment of  dividends  and other  distributions;  and
otherwise  assisting  the Fund in the  conduct of its  business,  subject to the
direction and control of the Fund's Board of Trustees.

Under the Investment  Management  Agreement,  the Fund is responsible  for other
expenses,  including  organizational expenses (including out-of-pocket expenses,
but not including the Investment Manager's overhead or employee costs); brokers'
commissions or other costs of acquiring or disposing of any portfolio securities
of the Fund;  legal,  auditing and  accounting  expenses;  payment for portfolio
pricing or valuation services to pricing agents, accountants,  bankers and other
specialists,  if any; taxes and governmental  fees; the fees and expenses of the
Fund's transfer agent;  expenses of preparing share  certificates  and any other
expenses,  including clerical  expenses,  of issuance,  offering,  distribution,
sale,  redemption  or  repurchase  of  Shares;  the  expenses  of and  fees  for
registering  or qualifying  securities  for sale; the fees and expenses of those
Trustees  who are not  "interested  persons" of the Fund (as defined in the 1940
Act); the cost of printing and  distributing  reports,  notices and dividends to
current  shareholders;  and the  fees and  expenses  of the  Fund's  custodians,
subcustodians,  dividend disbursing agents and registrars.  The Fund may arrange
to have third parties  assume all or part of the expenses of sale,  underwriting
and  distribution  of  Shares.  The Fund is also  responsible  for  expenses  of
shareholders'  and other meetings and its expenses  incurred in connection  with
litigation  and the  legal  obligation  it may have to  indemnify  officers  and
Trustees of the Fund with respect thereto.  The Fund is also responsible for the
maintenance  of books and records  which are  required to be  maintained  by the
Fund's  custodian  or other  agents of the Fund;  telephone,  telex,  facsimile,
postage and other communications  expenses; any fees, dues and expenses incurred
by  the  Fund  in  connection  with  membership  in  investment   company  trade
organizations;  expenses of printing and mailing  prospectuses and statements of
additional   information  of  the  Fund  and  supplements   thereto  to  current
shareholders; costs of stationery; fees payable to the Investment Manager and to
any other Fund advisers or consultants; expenses relating to investor and public
relations; interest charges, bond premiums and other insurance expense; freight,
insurance  and other  charges  in  connection  with the  shipment  of the Fund's
portfolio securities; and other expenses.

The Investment  Manager is responsible for the payment of the  compensation  and
expenses  of  all  Trustees,  officers  and  executive  employees  of  the  Fund
(including  the Fund's share of payroll  taxes)  affiliated  with the Investment
Manager and making available,  without expense to the Fund, the services of such
Trustees,  officers and  employees as may duly be elected  officers of the Fund,
subject to their individual  consent to serve and to any limitations  imposed by
law. The Fund is responsible for the fees and expenses  (specifically  including
travel  expenses  relating to Fund business) of Trustees not affiliated with the
Investment Manager  ("Non-Interested  Trustees") Under the Investment Management
Agreement,  the Investment  Manager also pays the Fund's share of payroll taxes.
During the Fund's most recent fiscal year, no compensation,  direct or otherwise
(other than through  fees paid to the  Investment  Manager),  was paid or became


                                       12
<PAGE>

payable by the Fund to any of its officers or Trustees who were  affiliated with
the Investment Manager.


On February 3, 1998, the Board of Trustees and the Investment  Manager agreed to
add a breakpoint to the investment  management  fee, such that the Fund pays the
Investment  Manager a fee based on an annual rate of 1.00% on the Fund's  ending
daily net  assets up to and  including  $500  million,  and 0.90% on the  Fund's
ending  daily net assets in excess of $500  million.  For the fiscal  year ended
October  31,  1998,  the Fund paid  investment  management  fees of  $5,556,255.
Additionally,  in accordance with an Administrative Agreement, the Fund pays the
Investment Manager a monthly fee based on the annual rate of 0.10% on the Fund's
ending daily net assets for administrative services.


The Investment Management Agreement further provides that the Investment Manager
shall not be liable for any error of  judgment or mistake of law or for any loss
suffered by any Fund in connection with matters to which such agreement relates,
except a loss resulting from willful misfeasance,  bad faith or gross negligence
on the part of the Investment  Manager in the  performance of its duties or from
reckless disregard by the Investment Manager of its obligations and duties under
such agreement.  The Investment Management Agreement also provides that purchase
and sale  opportunities,  which are  suitable  for more  than one  client of the
Investment Manager,  will be allocated by the Investment Manager in an equitable
manner. Lastly, the Investment Management Agreement contains a provision stating
that it supersedes all prior agreements.

The Investment Management Agreement may be terminated without penalty upon sixty
days' written notice by either party.  The Fund may agree to the  termination of
its  Investment  Management  Agreement  either by the vote of a majority  of the
outstanding  voting  securities  of the  Fund,  or by a vote  of  the  Board  of
Trustees. The Investment Management Agreement may also be terminated at any time
without penalty by the vote of a majority of the outstanding  voting  securities
of the Fund or by a vote of the Board of  Trustees if a court  establishes  that
the Investment  Manager or any of its officers or directors has taken any action
resulting in a breach of the Investment Manager's covenants under the Investment
Management  Agreement.  As stated above,  the  Investment  Management  Agreement
automatically terminates in the event of its assignment.

For the fiscal years ended  October 31, 1998,  1997,  and 1996,  the  Investment
Manager or its predecessor  was paid  investment  management fees of $5,556,255,
$4,880,120, and $4,517,293, respectively.

TRUSTEES AND OFFICERS

The Fund has a Board  composed  of four  Trustees  which  supervises  the Fund's
investment  activities and reviews contractual  arrangements with companies that
provide the Fund with  services.  The Trustees and officers and their  positions
with the Fund and their present and principal  occupations  during the past five
years are listed below.  Each Trustee who is an "interested  person" of the Fund
(as defined in the 1940 Act) is indicated by an asterisk (*).  Each  Independent
Trustee serves on the Audit Committee of the Board.

All of the officers and Trustees of the Fund hold comparable  positions with the
15 mutual funds,  consisting of 53 separate portfolios,  managed or administered
by INVESCO and distributed by INVESCO Distributors,  Inc. (the "INVESCO Funds"),
excluding the Fund.


                                       13
<PAGE>

The Trustees and Executive  Officers of the Fund and their principal occupations
during the last five years are set forth below.

NAME AND AGE          POSITION WITH    PRINCIPAL OCCUPATIONS DURING THE PAST
                      THE FUND         FIVE YEARS
- -----------           ------------     ------------------
CHARLES W. BRADY,     CHAIRMAN OF THE  Chief  Executive  Officer and Director of
Age 64*               BOARD SINCE      AMVESCAP  PLC,  London,  England,  and of
                      1991(MR.  BRADY  various  subsidiaries  thereof;  Chairman
                      DID NOT SERVE    of the Boards of the INVESCO Funds.
                      AS A TRUSTEE
                      BETWEEN
                      2/28/1997 AND
                      8/3/1998)

FRED A. DEERING,      TRUSTEE SINCE    Vice   Chairman  of  the  Boards  of  the
Age 71                1992             INVESCO  Funds;  formerly Chairman of the
                                       Executive  Committee  and Chairman of the
                                       Board of  Directors  of Security  Life of
                                       Denver   Insurance    Company,    Denver,
                                       Colorado;   Director   of  ING   American
                                       Holdings   Company  and  First  ING  Life
                                       Insurance Company of New York.

JOHN W. McINTYRE,     TRUSTEE SINCE    Retired.   Formerly,   Vice  Chairman  of
Age 68                1991             the  Board of  Directors  of the Citizens
                                       and Southern  Corporation and Chairman of
                                       the Board and Chief Executive  Officer of
                                       the Citizens and Southern  Georgia  Corp.
                                       and Citizens and Southern  National Bank.
                                       Director/Trustee of the INVESCO Funds and
                                       Kaiser Foundation Health Plan of Georgia,
                                       Inc.,    Gables     Residential    Trust,
                                       Employee's Retirement System of GA, Emory
                                       University,   and  J.M.  Tull  Charitable
                                       Foundation.

DR.  LARRY SOLL,      TRUSTEE SINCE    Retired.   Formerly,   Chairman   of  the
Age 56                1991             Board  (1987 to 1994),   Chief  Executive
                                       Officer (1982 to 1989;  1993 to 1994) and
                                       President (1982 to 1989) of Synergen Inc.
                                       (a   biotechnology   company),   Boulder,
                                       Colorado. Director/Trustee of the INVESCO
                                       Funds.  Director  of  Synergen  since its
                                       incorporation  in 1982.  Director of Isis
                                       Pharmaceuticals, Inc.

MARK H.  WILLIAMSON,  PRESIDENT AND    President,  Chief  Executive Officer, and
Age 47                CHIEF OPERATING  Director,   INVESCO   Distributors  Inc.;
                      OFFICER SINCE    President,  Chief  Executive  Officer and
                      1998             Chairman,  INVESCO;   Formerly,  Chairman
                                       of the Board and Chief Executive Officer,
                                       NationsBanc  Advisors,  Inc. (1995-1997);
                                       Chairman   of  the   Board,   NationsBanc
                                       Investments, Inc. (1997-1998).


                                       14
<PAGE>

RONALD L.  GROOMS,    TREASURER SINCE  Senior  Vice  President  and Treasurer of
Age 52                1991             INVESCO    Funds   Group,   Inc.   (since
                                       1988).    Senior   Vice   President   and
                                       Treasurer of INVESCO  Distributors,  Inc.
                                       (since 1997).

GLEN A.  PAYNE,       SECRETARY SINCE  Senior  Vice  President,  General Counsel
Age 52                1991             and  Secretary  of  INVESCO  Funds Group,
                                       Inc.    (since    1995),    and   INVESCO
                                       Distributors,  Inc.  (since  1997);  Vice
                                       President,  Secretary and General Counsel
                                       of INVESCO Funds Group, Inc. (May 1989 to
                                       April 1995); formerly, employee of a U.S.
                                       regulatory agency, Washington, D.C. (June
                                       1973 through May 1989).

JOHN R.  SCHROER,     VICE PRESIDENT   Senior  Vice  President of INVESCO  Funds
Age 32                SINCE 1996       Group,  Inc.  and  portfolio  manager  of
                                       the Fund (since 1996).  Portfolio manager
                                       of the INVESCO  Strategic Health Sciences
                                       Fund.


Unless otherwise  indicated, the address of each Trustee and officer of the Fund
is Post Office Box 173706, Denver, Colorado 80217-3706.
- --------
*Because of  Mr. Brady's  affiliation with INVESCO, or with companies affiliated
with INVESCO, he is deemed to be an "interested person" of INVESCO Global Health
Sciences Fund, as that term is defined in the 1940 Act.

The Board has an Audit Committee that is composed of Messrs.  Deering,  Soll and
McIntyre.  The  Committee  makes  recommendations  regarding  the  selection  of
independent  auditors  for the  Fund,  confers  with  the  independent  auditors
regarding  the Fund's  financial  statements,  the results of audits and related
matters, and performs other tasks as the Board assigns.










                                       15
<PAGE>

COMPENSATION OF TRUSTEES

The  Trustees  and officers who are  "interested  persons" as  designated  above
receive no  compensation  from the Fund.  The table below shows  amounts paid or
accrued to those Trustees who are not designated "interested persons" during the
Fund's fiscal year ended October 31, 1998, except that the information regarding
the total  compensation from the Fund and Fund Complex in the last column is for
the calendar year 1998.

The  following  table  shows  the  compensation  paid by the  Fund to its  three
Independent  Trustees  for their  services as Trustees of the Fund in the fiscal
year  ended  October  31,  1998.  The  following  table  also  shows  the  total
compensation paid by the Fund and the INVESCO Funds (collectively,  the 54 funds
of the  "INVESCO  Complex",  including  the  Fund) to these  Trustees  for their
services as Directors or Trustees during the year ended December 31, 1998.

COMPENSATION TABLE

                       AMOUNTS PAID DURING THE MOST RECENT
                       FISCAL YEAR BY THE FUND TO TRUSTEES
                                                                    TOTAL
                                                                COMPENSATION
                    AGGREGATE      BENEFITS      ESTIMATED     FROM THE FUND
                  COMPENSATION    ACCRUED AS      ANNUAL        AND INVESCO
                    FROM THE     PART OF FUND  BENEFITS UPON   FUNDS PAID TO
NAME OF TRUSTEE       FUND        EXPENSES(2)  RETIREMENT(3)     TRUSTEES
- ---------------       ----        -----------  -------------     --------


FRED A. DEERING      $19,000         $0.00          $0.00         $103,700
JOHN W. MCINTYRE(1)  $20,000         $0.00          $0.00         $ 98,500
DR.  LARRY SOLL      $19,000         $0.00          $0.00         $ 96,000
                     -------         -----          -----         --------

TOTAL                $58,000         $0.00          $0.00         $298,200
- -----
AS A PERCENTAGE OF NET
ASSETS              0.0099%(4)                                    0.0014%(5)
- ------


1 The chairman of the audit committee receives  compensation for serving in such
capacity in addition to the compensation paid to all Independent Trustees.

2  Represents  benefits  accrued with  respect to the Defined  Benefit  Deferred
Compensation Plan discussed below, and not compensation deferred at the election
of the  Trustees.  This Plan was adopted by the Board of Trustees on October 12,
1998,  and as of October 31, 1998,  the Fund's fiscal year end, no benefits have
begun accruing to eligible Trustees.

3 These figures  represent the Fund's estimated annual benefits payable upon the
trustee's  retirement.  These estimated benefits assume retirement at age 72 and
that the basic  retainer  payable to the Trustees will be adjusted  periodically
for  inflation.  This results in lower  estimated  benefits for Trustees who are
closer to retirement and higher estimated  benefits for Trustees who are farther
from  retirement.  Each of these  Trustees has served as Trustee for the minimum
five-year  period  required to be eligible to participate in the Defined Benefit
Deferred Compensation Plan.

4 Total as a percentage of the Fund's net assets as of October 31, 1998.

5 Total as a percentage  of the INVESCO  Complex's net assets as of December 31,
1998.


The Fund's Independent Trustees (as defined under the 1940 Act) and of the other
funds in the INVESCO Complex  establish their own compensation from the Fund and
other funds in the INVESCO Complex and are not paid by INVESCO or any affiliated
company.  Mr. Brady, as an "interested person" of the Fund and of other funds in
the INVESCO Complex, receives compensation as an officer of companies affiliated
with INVESCO,  but does not receive any trustee fees or other  compensation from
the Fund or from other funds in the INVESCO Complex for his service as a Trustee
or Director.

The  Board of  Trustees  of the Fund has  adopted  a  Defined  Benefit  Deferred
Compensation Plan (the "Benefit Plan") for the Independent Trustees of the Fund.
Under the Benefit Plan, each Trustee who is not an interested person of the Fund
(as  defined in  Section  2(a)(19)  of the 1940 Act),  and who has served for at
least five years (a "Qualified  Trustee") is entitled to receive four  quarterly
payments during the first twelve months after his or her  retirement,  with each
payment to be equal to 25 percent of the sum of the annual  basic  retainer  and


                                       16
<PAGE>

annualized  quarterly  board meeting fees payable by the Fund to the Independent
Trustee on his or her retirement (the "First Year Retirement Payment"). Trustees
normally  retire at age 72, 73, 74 or 75 if the  retirement  date is extended by
the  Board.  In no event may a  Trustee  retire  later  than the last day of the
calendar quarter in which the Trustee's seventy-fifth birthday occurs.

Beginning with the first anniversary of the Qualified Trustee's retirement,  and
beginning as of the  retirement of an  Independent  Trustee whose  retirement is
after the date of the last day of the calendar  quarter in which such  Trustee's
seventy-fifth  birthday occurred,  the Independent Trustee will receive, for the
remainder of his or her life, a benefit (the "Benefit"), payable quarterly, with
each  quarterly  payment  to be equal to 12.50% of the sum of the  annual  basic
retainer and annualized quarterly Board meeting fees payable by the Trust to the
Independent Trustee on his or her retirement.

If an Independent Trustee's service as a Trustee is terminated because of his or
her death  after the last day of the  calendar  quarter in which such  Trustee's
seventy-second birthday occurred and before the last day of the calendar quarter
in  which  such  Trustee's   seventy-fifth   birthday  occurs,   the  designated
beneficiary of the  Independent  Trustee will receive the First Year  Retirement
Payments and will, beginning with the quarter following the quarter in which the
last First Year Retirement  Payment is made, receive the Benefit for a period of
ten years, with quarterly payments to be made to the designated beneficiary.

If an Independent Trustee's service as a Trustee is terminated because of his or
her death  before the last day of the calendar  quarter in which such  Trustee's
seventy-second  birthday occurs or after the last day of the calendar quarter in
which such Trustee's seventy-fifth birthday occurred, the designated beneficiary
of the  Independent  Trustee will receive the Benefit for a period of ten years,
with quarterly  payments to be made to the designated  beneficiary  beginning in
the first quarter following the Trustee's death.

If an Independent Trustee's service as a Trustee is terminated because of his or
her  disability  after  the  last day of the  calendar  quarter  in  which  such
Trustee's  seventy-second  birthday  occurred  and  before  the  last day of the
calendar  quarter in which such Trustee's  seventy-fifth  birthday  occurs,  the
Independent  Trustee will receive the First Year  Retirement  Payments and will,
beginning  with the quarter  following  the quarter in which the last First Year
Retirement  Payment is made, receive the Benefit for the remainder of his or her
life, with quarterly payments to be made to the disabled Independent Trustee. If
the disabled  Independent  Trustee  should die before the First Year  Retirement
Payments are completed  and before forty  quarterly  Benefit  payments are made,
such payments will continue to be made to the Independent  Trustee's  designated
beneficiary until the aggregate of the First Year Retirement  Payments and forty
quarterly  Benefit payments have been made to the disabled  Independent  Trustee
and the Trustee's designated beneficiary.

If an Independent Trustee's service as a Trustee is terminated because of his or
her  disability  before  the  last day of the  calendar  quarter  in which  such
Trustee's  seventy-second  birthday occurs or after the last day of the calendar
quarter in which such Trustee's seventy-fifth birthday occurred, the Independent
Trustee  will  receive the Benefit for the  remainder  of his or her life,  with
quarterly payments to be made to the disabled  Independent  Trustee beginning in
the first quarter  following the Trustee's  termination for  disability.  If the
disabled  Independent  Trustee  should die before forty  quarterly  payments are
made, payments will continue to be made to the Independent  Trustee's designated
beneficiary until the aggregate of forty quarterly payments has been made to the
disabled Independent Trustee and the Trustee's designated beneficiary.


                                       17
<PAGE>

Any question  involving  entitlement to payments under or the  administration of
the Benefit Plan will be referred to a four-person  committee (the  "Committee")
composed of three  Independent  Trustees  designated  by all of the  Independent
Trustees and one Trustee who is not an  Independent  Trustee,  designated by the
non-Independent  Trustee.  Except as otherwise provided, the Committee will make
all  interpretations  and determinations  necessary or desirable for the Benefit
Plan's administration, and such interpretations and determinations will be final
and conclusive. Committee members will be elected annually.

The  Committee  will  represent and act on behalf of the Trust in respect of the
Benefit  Plan and,  subject to the other  provisions  of the Benefit  Plan,  the
Committee may adopt, amend or repeal bylaws or other regulations relating to the
administration of the Benefit Plan, the conduct of the Committee's  affairs, its
rights or powers,  or the rights or powers of its members.  The  Committee  will
report to the  Independent  Trustees  and to the Board  from time to time on its
activities in respect of the Benefit Plan.  The Committee or persons  designated
by it  will  cause  such  records  to be  kept  as  may  be  necessary  for  the
administration  of the Benefit Plan. The cost of the Benefit Plan is paid by the
Trust.

On October 12, 1998,  the Board of Trustees  adopted a Deferred  Fee  Agreement,
pursuant to which the Independent Trustees may defer receipt of a portion of the
compensation  which they would otherwise have been paid as Trustees of the Fund.
The deferred amount is invested in Shares. Each Independent Trustee,  therefore,
may be an indirect owner of Shares,  in addition to any Shares that may be owned
directly.

OWNERSHIP OF FUND SHARES


As of March 26, 1999, no persons owned,  beneficially or of record, more than 5%
of the outstanding  Shares.  Also on that date, the Trustees and officers of the
Fund, as a group,  beneficially  owned less than one percent of the  outstanding
shares of the Fund.


                             PORTFOLIO TRANSACTIONS

The  Investment  Manager  places  orders for the purchase and sale of securities
with  brokers  and  dealers   based  upon  its   evaluation   of  the  financial
responsibility  of the brokers and  dealers,  and  considering  the brokers' and
dealers'  ability  to effect  transactions  at the best  available  prices.  The
Investment Manager evaluates the overall reasonableness of brokerage commissions
paid by reviewing the quality of executions  obtained on portfolio  transactions
of the Fund,  viewed  in terms of the size of  transactions,  prevailing  market
conditions in the security  purchased or sold,  and general  economic and market
conditions.  In seeking to ensure that any commissions or discounts  charged the
Fund are consistent with prevailing and reasonable  commissions,  the Investment
Manager also endeavors to monitor  brokerage  industry  practices with regard to
the commissions  charged by  broker-dealers  on transactions  effected for other
comparable   institutional   investors.   While  the  Investment  Manager  seeks
reasonably  competitive  rates,  the Fund does not  necessarily  pay the  lowest
commission, spread or discount available.

Consistent  with the  standard  of  seeking  to  obtain  the best  execution  on
portfolio  transactions,  the Investment Manager may select brokers that provide
research  services to effect such  transactions.  Research  services  consist of
statistical and analytical reports relating to issuers,  industries,  securities
and  economic  factors and trends,  which may be of  assistance  or value to the
Investment Manager in making informed  investment  decisions.  Research services
prepared and  furnished  by brokers  through  which the Funds effect  securities
transactions  may be used by the  Investment  Manager  in  servicing  all of its
accounts  and not all such  services  may be used by the  Investment  Manager in
connection with the Fund.


                                       18
<PAGE>


In  recognition  of the  value of the  above-described  brokerage  and  research
services provided by certain brokers,  the Investment  Manager,  consistent with
the standard of seeking to obtain the best execution on portfolio  transactions,
may place orders with such brokers for the  execution  of  transactions  for the
Fund on which the  commissions  are in excess of those which other brokers might
have charged for effecting the same transactions.

Portfolio  transactions may be effected through  qualified  broker-dealers  that
recommend  the Fund to their  clients or who act as agent in the purchase of the
Shares for their  clients.  When a number of brokers  and  dealers  can  provide
comparable best price and execution on a particular transaction,  the Investment
Manager may consider the sale of Shares by a broker or dealer in selecting among
qualified broker-dealers.


The Fund paid $1,511,837,  $1,746,140,  and $1,685,692 in brokerage  commissions
during the fiscal  years  ended  October  31,  1998,  1997,  and 1996.  Of these
amounts, $5,812, $64,276, and $19,426 were paid to the Dealer Manager.


PORTFOLIO TURNOVER

Generally, the Fund will not purchase securities for short-term trading profits.
However, the Fund may dispose of securities without regard to the time they have
been held when such actions, for defensive or other reasons, appear advisable to
the Investment  Manager.  (The portfolio turnover rate is calculated by dividing
the lesser of  purchases  or sales of portfolio  securities  for the  particular
fiscal  year by the  monthly  average of the value of the  portfolio  securities
owned by the Fund during the particular fiscal year. For purposes of determining
this rate, all securities  whose  maturities at the time of acquisition  are one
year or less are  excluded.)  The  annual  rate of the  Fund's  total  portfolio
turnover for the years ended  December 31, 1998,  1997,  and 1996 was 87%, 145%,
and 91%, respectively.

                     REPURCHASE OF SHARES AND TENDER OFFERS

Shares of closed-end funds frequently trade at a discount from NAV per share but
in some cases trade at a premium.  In  recognition of the  possibility  that the
Shares  might  similarly  trade at a discount,  the Fund's Board of Trustees has
determined that it would be in the interest of shareholders for the Fund to take
action to attempt to reduce or  eliminate a market value  discount  from NAV. To
that end,  the Board  contemplates  that the Fund  could  from time to time take
action either to  repurchase  its Shares in the open market or to tender for its
own Shares at NAV. The Board, in consultation with the Investment Manager,  will
review on a quarterly  basis the possibility of open market  repurchases  and/or
tender offers for Shares.  There are no assurances that the Board will, in fact,
decide to undertake either of these actions or, if undertaken, that such actions
will result in the Shares  trading at a market  price per Share that is equal to
or approximates their NAV per Share. In addition, the Board will not necessarily
announce when it has given consideration to these matters.

Subject to the Fund's  investment  policies  and  restrictions  with  respect to
borrowings,  the Fund may incur debt to finance repurchases and/or tenders.  See
"Investment   Objective  and  Policies"  in  the  Prospectus   and   "Investment
Restrictions" herein. Interest on any such borrowings will reduce the Fund's net
investment income.

The Fund  anticipates that the market price of its Shares will from time to time
vary from their NAV per Share.  The market  price of the per Share  will,  among
other  things,  be  determined  by the  relative  demand for and supply of those
Shares in the market, the Fund's investment performance, its dividends and yield
and  investor  perception  of its overall  attractiveness  as an  investment  as
compared with other  investment  alternatives.  Nevertheless,  the fact that the


                                       19
<PAGE>

Shares may be repurchased or be the subject of tender offers at NAV from time to
time may reduce the spread  between  market  price and NAV that might  otherwise
exist. In the opinion of the Investment Manager, sellers may be more inclined to
accept a  significant  discount if they have a reasonable  expectation  of being
able to recover NAV in conjunction with a possible repurchase or tender offer.

Although the Board of Trustees believes that share repurchases and tender offers
generally would have a favorable effect on the market price per Share, it should
be recognized that the acquisition of Shares by the Fund will decrease its total
assets and, therefore,  have the effect of increasing its expense ratio. Because
of the nature of the Fund's investment objective and policies and its portfolio,
the Investment  Manager does not anticipate  that  repurchases and tender offers
should have a materially adverse effect on the Fund's investment performance and
does not anticipate any material difficulty in disposing of portfolio securities
in order to consummate share repurchases and tender offers.

It is the Board of Trustees' announced policy,  which the Board may change, that
the Fund cannot accept tenders or effect  repurchases if (1) such  transactions,
if consummated, would (a) result in delisting the Shares from the NYSE (the NYSE
having advised the Fund that it would consider delisting if the aggregate market
value of the outstanding Shares is less than $5,000,000,  the number of publicly
held Shares falls below  600,000 or the number of round-lot  holders falls below
1,200) or (b)  terminate  the Fund's  status as a regulated  investment  company
under the Code  (which  would  cause the Fund's  income to be taxed at the trust
level in addition to being taxed when the  shareholders  receive  dividends from
the Fund),  (2) the amount of securities  tendered would require  liquidation of
such a substantial portion of the Fund's securities that it would not be able to
liquidate  portfolio  securities  in an orderly  manner in light of the existing
market  conditions and such liquidation  would have an adverse effect on the NAV
of the Fund to the detriment of  nontendering  shareholders  or (3) there is, in
the Board of Trustees'  judgment,  any  material (a) legal action or  proceeding
instituted or threatened  challenging such transactions or otherwise  materially
adversely  affecting  the Fund,  (b)  suspension  of or limitation on prices for
trading  securities  generally  on the  NYSE or any  foreign  exchange  on which
portfolio  securities  of the Fund are  traded,  (c)  declaration  of a  banking
moratorium by federal, state or foreign authorities or any suspension of payment
by banks in the United States,  New York State or foreign countries in which the
Fund invests,  (d) limitation affecting the Fund or the issuers of its portfolio
securities imposed by federal,  state or foreign authorities on the extension of
credit by lending  institutions  or on the  exchange  of foreign  currency,  (e)
commencement  of war,  armed  hostilities  or other  international  or  national
calamity  directly or indirectly  involving the United States or other countries
in which the Fund  invests  or (f) other  event or  condition  that would have a
material  adverse  effect  on  the  Fund  or its  shareholders  if  Shares  were
repurchased.  The Board of  Trustees  may modify  these  conditions  in light of
experience.


Any tender  offer made by the Fund will be at a price equal to the NAV per Share
on a date  subsequent to the Fund's receipt of all tenders.  During the pendency
of any tender offer by the Fund, it will  calculate  daily the NAV of the Shares
and will  establish  procedures  that  will be  specified  in the  tender  offer
documents, to enable shareholders to ascertain readily such NAV. Each offer will
be made and shareholders will be notified in accordance with the requirements of
the Securities  Exchange Act of 1934 and the 1940 Act,  either by publication or
mailing or both. Each offering document will contain the information  prescribed
by those  laws and the  rules and  regulations  promulgated  thereunder.  When a
tender offer is  authorized  to be made by the Fund's  Trustees,  a  shareholder
wishing to accept the offer  will be  required  to tender all (but not less than
all) of the Shares owned by the shareholder (or  constructively  owned by him or
her for federal  income tax purposes  under  section 318 of the Code).  The Fund
will not  specify a record  date for the  tender  offer  that will not  permit a
shareholder of record on the effective date of the tender offer to tender his or
her Shares.  The Fund will purchase all Shares  tendered in accordance  with the
terms of the offer unless it  determines  to accept none of them (based upon one
of the conditions set forth above). Each person tendering Shares will pay to the



                                       20
<PAGE>

Fund a reasonable  service charge to help defray  certain  costs,  including the
processing of tender forms,  effecting payment,  postage and handling. It is the
position  of the staff of the SEC that such  service  charge may not be deducted
from the proceeds of the purchase.  The Fund's  transfer  agent will receive the
fee as an  offset  to these  costs.  The Fund  expects  the costs to the Fund of
effecting  a tender  offer will  exceed the  aggregate  of all  service  charges
received from those who tender their Shares.  Costs  associated  with the tender
will be charged against capital.

Tendered  Shares that have been  accepted and purchased by the Fund will be held
in treasury and may be retired by the Trustees. Treasury Shares will be recorded
and reported as an offset to  shareholders'  equity and accordingly  will reduce
the Fund's  total  assets.  If treasury  Shares are retired,  Shares  issued and
outstanding and capital in excess of par value will be reduced.

If the Fund must liquidate  portfolio  securities in order to purchase  tendered
Shares, it may realize gains and losses. The portfolio turnover rate of the Fund
may or may not be affected  by the Fund's  repurchases  of Shares  pursuant to a
tender offer.

                                    TAXATION


Set  forth  below  is  a  discussion   of  certain  U.S.   federal   income  tax
considerations affecting the Fund and the purchase, ownership and disposition of
Shares.  This  discussion  does not  purport to be  complete or to deal with all
aspects of federal income taxation that may be relevant to shareholders in light
of  their  particular  circumstances.   This  discussion  is  based  on  current
provisions  of  the  Code,  the  regulations  promulgated  thereunder,  judicial
decisions and administrative pronouncements,  all of which are subject to change
(some of which may be retroactive).  Prospective  investors should consult their
own tax  advisors  with regard to the  federal  income tax  consequences  of the
purchase,  ownership and disposition of Shares,  as well as the tax consequences
arising under the laws of any state, foreign or other taxing jurisdiction.


TAX TREATMENT OF THE FUND


GENERAL.  The Fund has  elected,  qualified,  and intends to continue to qualify
each  year for  treatment  as a  regulated  investment  company  under  the Code
("RIC").  For each  taxable  year  that it so  qualifies,  the Fund (but not its
shareholders)  will  be  relieved  of  federal  income  tax on the  part  of its
investment  company  taxable  income  (consisting  generally  of net  investment
income,  net short-term capital gain and net gains from certain foreign currency
transactions)  and net capital  gain (the excess of net  long-term  capital gain
over net short-term capital loss) that it distributes to its shareholders.


To qualify for treatment as a RIC, the Fund must distribute to its  shareholders
for each  taxable year at least 90% of its  investment  company  taxable  income
("Distribution  Requirement")  and must meet  several  additional  requirements.
These requirements include the following:  (1) the Fund must derive at least 90%
of its gross income each taxable year from  dividends,  interest,  payments with
respect  to  securities  loans and gains from the sale or other  disposition  of
securities or foreign currencies, or other income (including gains from options,
futures or forward  contracts) derived with respect to its business of investing
in securities or those currencies  ("Income  Requirement");  (2) at the close of
each quarter of the Fund's  taxable year, at least 50% of the value of its total
assets must be represented by cash and cash items, U.S.  government  securities,
securities of other RICs and other  securities  that are limited,  in respect of
any one issuer,  to an amount that does not exceed 5% of the value of the Fund's
total  assets  and  that  does  not  represent  more  than  10% of the  issuer's
outstanding  voting  securities;  and (3) at the  close of each  quarter  of the
Fund's  taxable year,  not more than 25% of the value of its total assets may be


                                       21
<PAGE>

invested in securities of any one issuer (other than U.S. government  securities
or the securities of other RICs). If the Fund failed to qualify for treatment as
a RIC for any taxable year, it would be taxed as an ordinary  corporation on the
full  amount of its  taxable  income  for that  year  (even if that  income  was
distributed to its  shareholders)  and all distributions out of its earnings and
profits,  including  distributions  of net capital gain, would be taxable to its
shareholders as dividends (I.E.,  ordinary income). In addition,  the Fund could
be required to recognize  unrealized  gains, pay substantial  taxes and interest
and make substantial distributions before requalifying for RIC treatment.

The Fund will be subject to a non-deductible 4% excise tax ("Excise Tax") to the
extent it fails to distribute by the end of any calendar year  substantially all
of its  ordinary  income  for that  year and  capital  gain net  income  for the
one-year period ending on October 31st of that year, plus certain other amounts.
For these  purposes,  any such income retained by the Fund, and on which it pays
federal income tax, will be treated as having been distributed.

FOREIGN  SECURITIES.  The Fund may  invest  in the  stock  of  "passive  foreign
investment companies" ("PFICs"). A PFIC is any foreign corporation (with certain
exceptions) that, in general,  meets either of the following tests: (1) at least
75% of its gross  income is passive  income or (2) an average of at least 50% of
its assets  produce,  or are held for the production of, passive  income.  Under
certain  circumstances,  the Fund will be  subject  to  federal  income tax on a
portion of any "excess  distribution"  received on the stock of a PFIC or of any
gain on disposition of the stock  (collectively  "PFIC  income"),  plus interest
thereon,  even if the Fund  distributes  the PFIC  income as a  dividend  to its
shareholders.  The  balance of the PFIC  income  will be  included in the Fund's
investment company taxable income and, accordingly, will not be taxable to it to
the extent it distributes that income to its shareholders.

In lieu of the foregoing tax and interest obligation,  the Fund may, and intends
to,  elect to "mark to market"  its stock in any PFIC.  "Marking-to-market,"  in
this context,  means  including in ordinary income each taxable year the excess,
if any, of the fair  market  value of the stock over the Fund's  adjusted  basis
therein  as of the end of that year.  Pursuant  to the  election,  the Fund also
would be allowed to deduct (as an ordinary,  not capital,  loss) the excess,  if
any, of its adjusted  basis in PFIC stock over the fair market value  thereof as
of the taxable year-end,  but only to the extent of any net mark-to-market gains
with  respect to that  stock  included  in income by the Fund for prior  taxable
years under the election (and under regulations proposed in 1992 that provided a
similar  election  with  respect  to the stock of  certain  PFICs).  The  Fund's
adjusted basis in each PFIC's stock subject to the election would be adjusted to
reflect the amounts of income included and deductions taken thereunder.

Gains from the  disposition of foreign  currencies will be treated as qualifying
income under the Income Requirement. Gains or losses (1) from the disposition of
foreign  currencies,  including forward  contracts,  (2) on the disposition of a
foreign-currency-denominated debt security that are attributable to fluctuations
in the  value of the  foreign  currency  between  the dates of  acquisition  and
disposition  of the  security  and (3) that are  attributable  to exchange  rate
fluctuations  between the time the Fund  accrues  interest,  dividends  or other
receivables, or accrues expenses or other liabilities,  denominated in a foreign
currency and the time the Fund  actually  collects the  receivables  or pays the
liabilities,  generally  are treated as ordinary  income or loss.  These  gains,
referred  to under  the Code as  "section  988"  gains or  losses,  increase  or
decrease the amount of the Fund's investment company taxable income available to
be distributed to its shareholders as ordinary income, rather than increasing or
decreasing  the amount of its net capital gain.  In the case of overlap  between
sections  988 and 1256  (see  below  under  "Derivatives"),  special  provisions
determine the character and timing of any income, gain or loss.


Income received by the Fund from investments in Foreign Securities, and gains it
derives from the disposition thereof,  may be subject to income,  withholding or
other taxes imposed by foreign countries and U.S.  possessions that would reduce



                                       22
<PAGE>


the total return on its investments.  Tax conventions  between certain countries
and the United  States may reduce or eliminate  those taxes,  however,  and many
foreign countries do not impose taxes on capital gains in respect of investments
by foreign  investors.  Foreign taxes  withheld from or paid by the Fund will be
treated  as a Fund  expense  unless  it meets  the  requirements,  and  makes an
election,  to  enable  it,  in  effect,  to  pass  these  taxes  through  to its
shareholders  for  use by  them as a  foreign  tax  credit  or  deduction.  Each
shareholder will be notified annually whether the foreign taxes paid by the Fund
will "pass through" for that year and, if so, the  shareholder's  portion of (1)
the  foreign  taxes  paid by the Fund and (2)  dividends  paid by the Fund  that
represent income derived from foreign sources. Individuals who have no more than
$300 ($600 for married  persons  filing  jointly) of  creditable  foreign  taxes
included  on Forms 1099 and all of whose  foreign  source  income is  "qualified
passive income" may elect each year to be exempt from the extremely  complicated
foreign  tax  credit  limitation,  in which  event they would be able to claim a
foreign  tax  credit  without  having  to file the  detailed  IRS Form 1116 that
otherwise is required.


DERIVATIVES.  The use of  certain  derivatives,  such as selling  (writing)  and
purchasing  options and futures and entering  into forward  contracts,  involves
complex rules that will  determine  for federal  income tax purposes the amount,
character and timing of recognition of the gains and losses the Fund realizes in
connection therewith.  These rules also may require the Fund to "mark to market"
(that is, treat as sold for their fair market  value) at the end of each taxable
year certain  positions in its portfolio,  which may cause the Fund to recognize
income or gain without receiving cash with which to make distributions necessary
to satisfy the Distribution  Requirement and avoid imposition of the Excise Tax.
Gains from  options,  futures  and  forward  contracts  derived by the Fund with
respect to its business of investing in securities or foreign currencies will be
treated as qualifying income under the Income Requirement.


Certain futures and foreign currency  contracts in which the Fund may invest may
be subject to section 1256 of the Code ("section 1256  contracts").  Any section
1256  contracts  the Fund holds at the end of each taxable year (other than such
contracts that are part of a "mixed straddle" with respect to which the Fund has
elected   not  to  have  the   following   rules   apply)   generally   must  be
marked-to-market for federal income tax purposes.  Sixty percent of any net gain
or loss  recognized on these deemed  sales,  and 60% of any net realized gain or
loss from any  actual  sales of  section  1256  contracts,  will be  treated  as
long-term  capital gain or loss,  and the balance will be treated as  short-term
capital  gain or loss.  These rules may operate to increase  the amount that the
Fund must distribute to satisfy the Distribution Requirement (I.E., with respect
to the portion treated as short-term capital gain), which will be taxable to the
shareholders as ordinary income, to increase the net capital gain it recognizes,
and to increase  the amount it must  distribute  to avoid Excise Tax without any
corresponding receipt of cash by the Fund. The Fund may elect to exclude certain
transactions from the operation of section 1256,  although doing so may have the
effect of  increasing  the relative  proportion of net  short-term  capital gain
(taxable as ordinary  income) and thus  increasing  the amount of dividends that
must be distributed.


Gain or loss  realized by the Fund on the  expiration or sale of certain OTC put
and call options it holds will be either long-term or short-term capital gain or
loss,  depending  on its holding  period for the option.  However,  gain or loss
realized on the  expiration  or closing out of such  options that are written by
the Fund will be treated as short-term capital gain or loss. In general,  if the
Fund  exercises an option,  or an option that the Fund has written is exercised,
gain or loss on the option will not be  separately  recognized,  but the premium
received  or  paid  will  be  included  in the  calculation  of  gain or loss on
disposition of the property underlying the option.

Offsetting positions in any actively traded security, option, futures or forward
contract  entered  into or held by the  Fund may  constitute  a  "straddle"  for
federal  income tax  purposes.  Straddles  are subject to certain rules that may
affect the  amount,  character  and timing of the Fund's  gains and losses  with
respect to positions of the straddle by requiring,  among other things, that (1)


                                       23
<PAGE>

loss  realized on  disposition  of one position of a straddle be deferred to the
extent  of any  unrealized  gain in an  offsetting  position  until  the  latter
position  is  disposed  of, (2) the Fund's  holding  period in certain  straddle
positions not begin until the straddle is terminated (possibly resulting in gain
being treated as short-term  rather than long-term  capital gain) and (3) losses
recognized  with respect to certain  straddle  positions,  that otherwise  would
constitute  short-term  capital losses,  be treated as long-term capital losses.
Applicable  regulations  also provide certain "wash sale" rules,  which apply to
transactions where a position is sold at a loss and a new offsetting position is
acquired  within a  prescribed  period,  and "short  sale" rules  applicable  to
straddles. Different elections are available to the Fund, which may mitigate the
effects of the straddle rules, particularly with respect to any "mixed straddle"
(I.E., a straddle of which at least one, but not all, positions are section 1256
contracts).


If the Fund has an "appreciated  financial  position" -- generally,  an interest
(including an interest  through an option,  futures or forward contract or short
sale) with respect to any stock, debt instrument (other than "straight debt") or
partnership  interest the fair market value of which exceeds its adjusted  basis
- -- and  enters  into a  "constructive  sale" of the  position,  the Fund will be
treated as having made an actual sale thereof, with the result that gain will be
recognized at that time. A constructive sale generally consists of a short sale,
an  offsetting  notional  principal  contract  or a futures or forward  contract
entered  into by the  Fund or a  related  person  with  respect  to the  same or
substantially  identical  property.  In addition,  if the appreciated  financial
position  is  itself  a  short  sale  or  such a  contract,  acquisition  of the
underlying  property  or  substantially  identical  property  will be  deemed  a
constructive  sale. The foregoing will not apply,  however,  to any  transaction
during any taxable year that otherwise  would be treated as a constructive  sale
if the  transaction  is closed within 30 days after the end of that year and the
Fund holds the appreciated  financial  position  unhedged for 60 days after that
closing  (I.E.,  at no time during that 60-day period is the Fund's risk of loss
regarding that position reduced by reason of certain specified transactions with
respect to substantially identical or related property, such as having an option
to sell, being contractually  obligated to sell, making a short sale or granting
an option to buy substantially identical stock or securities).


TAX TREATMENT OF SHAREHOLDERS


Dividends from the Fund's investment company taxable income (whether received in
cash  or  reinvested  in  additional   Shares)  generally  are  taxable  to  its
shareholders  as  ordinary  income to the extent of its  earnings  and  profits.
Distributions  of the Fund's  net  capital  gain  (whether  received  in cash or
reinvested in additional Shares), when designated as capital gain distributions,
are taxable to its  shareholders  as long-term  capital gain,  regardless of how
long they have held their Shares. A participant in the Dividend Reinvestment and
Cash Purchase Plan  ("Reinvestment  Plan") will be treated as having  received a
distribution  in the  amount of the cash used to  purchase  Shares on his or her
behalf, including a PRO RATA portion of the brokerage fees incurred by the agent
under the  Reinvestment  Plan.  Distributions by the Fund to its shareholders in
any year that exceed its earnings and profits  generally  may be applied by each
shareholder  against  the basis for his or her  Shares  and will be  taxable  at
capital  gains  rates  (assuming  the Shares  are held as a capital  asset) to a
shareholder  to the  extent  the  distributions  to the  shareholder  exceed the
shareholder's  basis for his or her Shares.  Shareholders who are not liable for
tax on their income and whose  Shares are not  debt-financed  generally  are not
required to pay tax on  dividends or other  distributions  they receive from the
Fund.


A portion of the dividends  from the Fund's  investment  company  taxable income
(whether paid in cash or  reinvested  in additional  Shares) may be eligible for
the dividends-received  deduction allowed to corporations.  The eligible portion
may  not  exceed  the  aggregate  dividends  the  Fund  receives  from  domestic
corporations.  However,  dividends  received  by  a  corporate  shareholder  and
deducted  by  it  pursuant  to  the  dividends-received  deduction  are  subject


                                       24
<PAGE>

indirectly  to the  federal  alternative  minimum  tax.  The  Fund  will  notify
shareholders  of the amount of any dividends  that may be taken into account for
purposes of the  dividends-received  deduction  not later than 60 days after the
close of its taxable year.


The Fund may retain its net capital gain for investment  rather than  distribute
it to shareholders as capital gain distributions.  If the Fund does so, however,
it will be subject to a tax of 35% on the retained  amount.  In that event,  the
Fund expects to designate the retained amount as undistributed  capital gains in
a notice to its  shareholders,  who (1) will be  required  to  include  in their
taxable income,  as long-term  capital gain, their  proportionate  shares of the
retained amount,  (2) will be entitled to credit their  proportionate  shares of
the tax paid by the Fund against their federal income tax  liabilities  and, for
any shareholder  whose share of that tax exceeds his or her tax liabilities,  to
claim a  refund,  and (3) will  increase  the tax  basis of their  Shares by the
difference  between  the  included  income and such share of the tax paid by the
Fund.


The Fund will notify its shareholders following the end of each calendar year of
the amounts of dividends  and capital gain  distributions  paid (or deemed paid)
that year and undistributed capital gain designated for that year.

Investors should be aware that if Shares are purchased shortly before the record
date for any  dividend or other  distribution,  they will pay full price for the
Shares and will receive  some  portion of the  purchase  price back as a taxable
distribution.

On the  sale  or  exchange  of  Shares  (including  a sale  pursuant  to a Share
repurchase or tender offer by the Fund), a shareholder  generally will recognize
a taxable gain or loss equal to the difference between his or her adjusted basis
for the Shares and the amount received. Any such gain or loss will be treated as
a capital  gain or loss if the  Shares  are held by the  shareholder  as capital
assets and will be  long-term  capital gain or loss if the Shares have been held
for more than one year. Any loss recognized on a sale or exchange of Shares that
were held for six  months or less will be  treated  as  long-term,  rather  than
short-term,  capital  loss  to the  extent  of any  capital  gain  distributions
previously  received  thereon.  A loss  realized on a sale or exchange of Shares
will be  disallowed  to the extent  those  Shares are  replaced by other  Shares
within a period of 61 days beginning 30 days before and ending 30 days after the
date of disposition of the Shares (which could occur,  for example,  as a result
of  participation  in the  Reinvestment  Plan). In that event,  the basis of the
replacement Shares will be adjusted to reflect the disallowed loss.


Net capital gain recognized by individuals and other non-corporate  taxpayers on
the sale or  exchange of capital  assets held for one year or less,  and all net
capital gain recognized by corporations,  is taxed at the same rates as ordinary
income. The maximum tax rate applicable to non-corporate  taxpayers' net capital
gain for capital  assets held longer than one year is 20% (10% for  taxpayers in
the 15% marginal tax bracket);  this rate applies to capital gain  distributions
by the Fund as well as to gains from sales and exchanges of Shares.


                              FINANCIAL STATEMENTS

PricewaterhouseCoopers  LLP are the  Fund's  independent  accountants  providing
audit and tax return  preparation  services and assistance and  consultation  in
connection   with  the  review  of  various   SEC   filings.   The   address  of
PricewaterhouseCoopers  LLP is 950 Seventeenth Street, Denver, Colorado,  80202.
The  financial  statements  incorporated  by  reference in this SAI have been so
incorporated and the financial  highlights  included in the Prospectus have been
so included, in reliance upon the report of PricewaterhouseCoopers  LLP given on
the authority of said firm as experts in accounting and auditing.


                                       25
<PAGE>

                           INCORPORATION BY REFERENCE

The Fund's  Annual  Report  for the fiscal  year  ended  October  31,  1998 (the
"Report"),  which either accompanies this SAI or has previously been provided to
the person to whom this SAI is being sent, is  incorporated  herein by reference
with  respect to all  information  other than the  information  set forth in the
Letter to Shareholders included therein. The Fund will furnish,  without charge,
a copy of its Report upon  written  request to INVESCO  Global  Health  Sciences
Fund, 7800 East Union Avenue, Denver, Colorado 80237, or call 1-800-528-8765, or
visit our website at http://ghs.invesco.com.




                                       26
<PAGE>

                            PART C OTHER INFORMATION

ITEM 24.  FINANCIAL STATEMENTS AND EXHIBITS

1.  Financial Statements

      (a) Financial Highlights - Contained in Part A

      (b) Incorporated in Part B by reference to Registrant's October 31, 1998
          Annual Report:


            1.  Statement of Investments Securities as of October 31, 1998


            2.  Statement of Assets and Liabilities as of October 31, 1998


            3.  Statement of Operations for the year ended October 31, 1998

            4.  Statement of Cash Flows for the year ended October 31, 1998

            5.  Statements of Changes in Net Assets for the years ended October
                31, 1998 and October 31, 1997


            6.  Notes to Financial Statements


            7.  Report of Independent Accountants dated December 8, 1998

            8.  Financial Highlights for each of the five years in the period
                ended October 31, 1998

2.  Exhibits


     (a)(1) Declaration of Trust of the Registrant (1)

     (a)(2) Amendment of the Declaration of Trust of the Registrant (1)

     (b)    By-Laws of the Registrant (1)

     (c)    Not Applicable


     (d)(1) Specimen Certificate for Shares of Beneficial Interest of the
            Registrant - Filed herewith

     (d)(2) Form of Subscription Certificate - Filed herewith

     (d)(3) Form of Notice of Guaranteed Delivery - Filed herewith

     (d)(4) Form of Nominee Holder Over-Subscription Exercise Form - Filed
            herewith


     (e)    Dividend Reinvestment and Cash Purchase Plan of the Registrant (1)

     (f)    Not Applicable

     (g)(1) Investment Management Agreement between the Registrant and INVESCO
            Funds Group, Inc. (1)


                                       27
<PAGE>

     (g)(2) Amendment to Investment Management Agreement (1)


     (h)    Underwriter Agreement between the Registrant and PaineWebber
            Incorporated - Filed herewith


     (i)(1) Deferred Fee Agreement (1)

     (i)(2) Defined Benefit Deferred Compensation Plan for Non-Interested
            Directors and Trustees (1)

     (j)(1) Custody Agreement between the Registrant and State Street Bank and
            Trust Company (1)

     (j)(2) Special Custody Account Agreement between the Registrant and Bear
            Stearns Securities Corporation (1)

     (j)(3) Special Custody Account Agreement between the Registrant and Herzog,
            Heine, Geduld (1)

     (k)(1) Form of Agency Agreement between the Registrant and State Street
            Bank and Trust Company (1)

     (k)(2) Administration Agreement between the Registrant and INVESCO Funds
            Group, Inc. (1)

     (k)(3) Amendment to Administration Agreement (1)


     (k)(4) Subscription Agreement with INVESCO Funds Group, Inc. - Filed
            herewith

     (l)    Opinion and Consent of Kirkpatrick & Lockhart LLP - Filed herewith


     (m)    Not Applicable


     (n)    Consent of PricewaterhouseCoopers LLP - Filed herewith


     (o)    Not Applicable


     (p)    Not Applicable


     (q)    Not Applicable


     (r)    Not Applicable

     (s)    Powers of Attorney - Filed herewith

___________________

(1)  Incorporated by reference from Registrant's Registration Statement (File
     No. 33-75831) filed on April 7, 1999.

ITEM 25.  MARKETING AGREEMENTS

      See Form of  Dealer Manager  Agreement to be  filed as Exhibit (h) to this
Registration Statement.

ITEM 26.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION


      Registration Fees.........................................35,000
      Printing and Engraving Expenses...........................38,453
      Rating Agency Fees and Expenses................................0
      Trustees' Fees and Expenses....................................0
      Legal Fees and Expenses..................................259,674



                                       28
<PAGE>


      New York Stock Exchange Listing Fees...........................0
      National Association of Securities Dealers, Inc. Fees.....11,100
      Accounting Fees and Expenses..............................17,500
      Dealer Manager Expense Reimbursement.....................100,000
      Subscription Agent Fees and Expenses......................70,334
      Information Agent's Fees and Expenses.....................63,639
      Federal Taxes..................................................0
      State Taxes....................................................0
      State Fees.....................................................0
      Miscellaneous Expenses.........................................0
      Total....................................................596,200


ITEM 27.  PERSONS CONTROLLED BY OR UNDER COMMON CONTROL

      Not Applicable.

ITEM 28.  NUMBER OF HOLDERS OF SECURITIES


      TITLE OF CLASS                    AS OF APRIL 30, 1999
      ----------------------------      ------------------------
      Shares of Beneficial Interest.....1687 RECORD HOLDERS


ITEM 29.  INDEMNIFICATION

Section 5.3 of the Registrant's  Declaration of Trust (Exhibit (a) hereto, which
is incorporated by reference herein) provides in effect that the Registrant will
indemnify its officers and Trustees  under certain  circumstances.  However,  in
accordance  with Section 17(h) and 17(i) of the  Investment  Company Act of 1940
and its own terms,  said Article of the Agreement and  Declaration of Trust does
not  protect  any  person  against  any  liability  to  the  Registrant  or  its
shareholders  to which he would  otherwise  be  subject  by reason of bad faith,
willful  misfeasance,  gross  negligence,  or reckless  disregard  of the duties
involved in the conduct of his office.

Insofar as indemnification  for liabilities  arising under the Securities Act of
1933 may be  permitted  to Trustees,  officers  and  controlling  persons of the
Registrant,  pursuant to the foregoing  provisions or otherwise,  the Registrant
has been advised that in the opinion of the SEC, such indemnification is against
public policy as expressed in the Act and is, therefore,  unenforceable.  In the
event that a claim for indemnification  against such liabilities (other than the
payment by the Registrant of expenses incurred or paid by a Trustee,  officer or
controlling  person of the Registrant in the  successful  defense of any action,
suit or proceeding) is asserted by such Trustee,  officer or controlling  person
in connection with the securities being registered,  the Registrant will, unless
in the  opinion  of its  counsel  the matter  has been  settled  by  controlling
precedent,  submit to a court of  appropriate  jurisdiction  the  question as to
whether such  indemnification by it is against public policy as expressed in the
Act and will be governed by the final adjudication of such issue.

ITEM 30.  BUSINESS AND OTHER CONNECTIONS OF INVESTMENT MANAGER

The description of the business of INVESCO Funds Group,  Inc. is set forth under
the caption  "Management  of the Fund" in the Prospectus and SAI forming part of
this Registration Statement.


                                       29
<PAGE>

The  information  as to the Directors and officers of INVESCO Funds Group,  Inc.
set forth in  INVESCO  Funds  Group's  Form ADV filed  with the  Securities  and
Exchange  Commission (File No. 811-6476) as amended through the date hereof,  is
incorporated herein by reference.

ITEM 31.  LOCATION OF ACCOUNTS AND RECORDS

INVESCO Global Health  Sciences Fund, 7800 East Union Avenue,  Denver,  Colorado
80237, or call  1-800-528-8765.  Accounts and Records of the Fund are maintained
at (i) the Fund's office at 7800 East Union, Avenue, Denver, Colorado, 80237 and
(ii) the  offices of INVESCO  Funds  Group,  Inc.  at 7800 East  Union,  Avenue,
Denver, Colorado, 80237.

In addition,  EquiServe, Inc., 150 Royall Street, Canton, MA 02021 maintains all
the  required  records  in  its  capacity  as  transfer,  dividend  paying,  and
shareholder service agent of the Registrant.

ITEM 32.  MANAGEMENT SERVICES

      Not Applicable.

ITEM 33.  UNDERTAKINGS


1.  The Registrant  undertakes  to suspend  the Offer  until the  Prospectus  is
amended if (1) subsequent to the effective date of this registration  statement,
the NAV declines more than ten percent from its NAV as of the effective  date of
this registration statement or (2) the NAV of the Shares exercisable pursuant to
the Rights that are the subject of this registration  statement  increases to an
amount  greater than the Proceeds as stated in the  Prospectus  included in this
registration statement.


2.  Not Applicable.

3.  Not Applicable.

4.  Not Applicable.

5.  The Registrant undertakes:

      a. for the purpose of determining  any liability  under the Securities Act
      of 1933, the information omitted from the form of prospectus filed as part
      of this registration statement in reliance upon Rule 430A and contained in
      a form of prospectus  filed by the Registrant  under Rule 497(h) under the
      Securities  Act of 1933  shall be deemed  to be part of this  registration
      statement as of the time it was declared effective; and

      b. for the purpose of determining  any liability under the Securities Act,
      each post-effective  amendment that contains a form of prospectus shall be
      deemed  to be a new  registration  statement  relating  to the  securities
      offered therein,  and the offering of the securities at that time shall be
      deemed to be the initial bona fide offering thereof.

6.  The  Registrant  undertakes  to  send  by  first  class  mail or other means
designed to ensure equally prompt delivery,  within two Business Days of receipt
of a written or oral request, any SAI.




                                       30
<PAGE>




SIGNATURES  Pursuant to the  requirements  of the Securities Act of 1933 and the
Investment Company Act of 1940, the Registrant has duly caused this Registration
Statement  to  be  signed  on  its  behalf  by  the  undersigned,  thereto  duly
authorized, in the City of Denver, State of Colorado on May 24, 1999.


INVESCO GLOBAL HEALTH SCIENCES FUND


By:     /s/  Mark H. Williamson     May 24, 1999
      ------------------------------------------
      Mark H. Williamson            DATE
      President


Pursuant to the  requirements of the Securities Act of 1933,  this  Registration
Statement  has been  signed  below by the  following  persons in the  capacities
indicated on the dates indicated.  The undersigned hereby constitute and appoint
Glen A. Payne, James F. Lummanick,  and Ronald L. Grooms, and each of them, with
full power to act without the other, his or her true and lawful attorney-in-fact
and agent, with full power and substitution and resubstitution,  for him or her,
and in his or her  name,  place  and  stead,  in any and all  capacities  (until
revoked in writing) to sign any and all amendments to the Registration Statement
of the INVESCO Global Health Sciences Fund (including  post-effective amendments
thereto),  and to file the same, with all exhibits thereto,  and other documents
in connection therewith,  with the SEC, granting unto said attorneys-in fact and
agents,  and each of them,  full power and  authority to do and perform each and
every act and thing ratifying and confirming all that said attorneys-in fact and
agents or any of them,  or their or his or her  substitute or  substitutes,  may
lawfully do or cause to be done by virtue hereof.


 By:    /s/  Mark H. Williamson     May 24, 1999
      ------------------------------------------
      Principal Executive Officer   DATE
      Mark H.  Williamson, President


By:     /s/  Ronald L. Grooms       May 24, 1999
      ------------------------------------------
      Principal Financial Officer   DATE
      Ronald L. Grooms Vice President and Treasurer


By:     /s/  John R. Schroer        May 24, 1999
      ------------------------------------------
      Vice President                DATE
      John R.  Schroer


By:     /s/  Glen A. Payne          May 24, 1999
      ------------------------------------------
      Secretary                     DATE
      Glen A.  Payne


By:   *                             May 24, 1999
      ------------------------------------------
      Trustee                       DATE
      Charles W.  Brady


                                       31
<PAGE>



 By:  *                             May 24, 1999
      ------------------------------------------
      Trustee                       DATE
      Fred A.  Deering


 By:  *                             May 24, 1999
      ------------------------------------------
      Trustee                       DATE
      John W.  McIntyre


 By:  *                             May 24, 1999
      ------------------------------------------
      Trustee                       DATE
      Dr.  Larry Soll

*By:    /s/  Glen A. Payne   May 24, 1999
      -----------------------------------
      Glen A.  Payne                DATE
      Attorney in Fact for the Trustees


                                       32
<PAGE>

                               INDEX OF EXHIBITS



(2)(a)(1) Declaration of Trust of the Registrant (1)
(2)(a)(2) Amendment to the Declaration of Trust of the Registrant (1)
(2)(b)    By-Laws of the Registrant (1)
(2)(d)(1) Specimen Certificate for Shares of Beneficial Interest of The
          Registrant - Filed herewith
(2)(d)(2) Form of Subscription Certificate - Filed herewith
(2)(d)(3) Form of Notice of Guaranteed Delivery - Filed herewith
(2)(d)(4) Form of Nominee Holder Over-Subscription Exercise Form - Filed
          herewith
(2)(e)    Dividend Reinvestment and Cash Purchase Plan of the Registrant (1)
(2)(g)(1) Investment Advisory Agreement between the Registrant and INVESCO
          Fund Group, Inc. (1)
(2)(g)(2) Amendment to Investment Management Agreement (1)
(2)(h)    Underwriter Agreement between the Registrant and PaineWebber
          Incorporated - Filed herewith
(2)(i)(1) Deferred Fee Agreement (1)
(2)(i)(2) Defined Benefit Deferred Compensation Plan for Non-Interested
          Directors and Trustees (1)
(2)(j)(1) Custody Agreement between the Registrant and State Street Bank and
          Trust Company (1)
(2)(j)(2) Special Custody Account Agreement between the Registrant and Bear
          Stearns Securities Corporation (1)
(2)(j)(3) Special Custody Account Agreement between the Registrant and Herzog,
          Heine, Geduld (1)
(2)(k)(1) Form of Agency Agreeement between the Registrant and State Street Bank
          and Trust Company (1)
(2)(k)(2) Administration Agreement between the Registrant and INVESCO Funds
          Group, Inc. (1)
(2)(k)(3) Amendment to Administration Agreement (1)
(2)(k)(4) Subscription Agreement with INVESCO Funds Group, Inc.
          - Filed herewith
(2)(l)    Opinion and Consent of Kirkpatrick & Lockhart LLP - Filed herewith
(2)(n)    Consent of PricewaterhouseCoopers LLP - Filed herewith
(2)(s)    Power of Attorney - Filed herewith


_______________

(1)  Incorporated by reference from Registrant's Registration Statement (File
     No. 33-75831) filed on April 7, 1999.


                                   [SPECIMEN]

SHARES OF BENEFICIAL INTEREST
PAR VALUE $.01

THIS  CERTIFICATE IS TRANSFERABLE IN BOSTON,  MASSACHUSETTS  OR IN NEW YORK, NEW
YORK.

[GRAPHIC OMITTED]

SEE REVERSE SIDE FOR CERTAIN DEFINITIONS.
CUSIP 46128N   10   9

SEE REVERSE FOR CERTAIN DEFINITIONS

                        THE GLOBAL HEALTH SCIENCES FUND

          ORGANIZED UNDER THE LAWS OF THE COMMONWEALTH OF MASSACHUSETTS

THIS CERTIFIES THAT ________________________
IS THE OWNER OF     ________________________
          FULLY PAID AND NON-ASSESSABLE SHARES OF BENEFICIAL INTEREST.

OF THE GLOBAL HEALTH SCIENCES FUND (HEREINAFTER CALLED THE FUND) TRANSFERABLE ON
THE BOOKS OF THE FUND BY THE  HOLDER  HEREOF,  IN  PERSON OR BY DULY  AUTHORIZED
ATTORNEY, UPON SURRENDER OF THIS CERTIFICATE PROPERLY ENDORSED. THIS CERTIFICATE
AND THE SHARES  REPRESENTED  THEREBY ARE ISSUED AND SHALL BE HELD SUBJECT TO ALL
OF THE  PROVISIONS  OF THE  DECLARATION  OF TRUST AND THE  BY-LAWS OF THE GLOBAL
HEALTH  SERVICES  FUND (A COPY OF  EACH  OF  WHICH  IS ON FILE AT THE  PRINCIPAL
OFFICES OF THE FUND), AND ALL AMENDMENTS  THERETO, TO ALL OF WHICH THE HOLDER BY
ACCEPTANCE HEREOF ASSENTS. THIS CERTIFICATE IS NOT VALID UNTIL COUNTERSIGNED AND
REGISTERED BY THE TRANSFER AGENT AND REGISTRAR. WITNESS THE SEAL OF THE FUND AND
THE SIGNATURES OF ITS DULY AUTHORIZED OFFICERS.

       [THE NAME HAS BEEN CHANGED TO INVESCO GLOBAL HEALTH SCIENCES FUND]

DATED:    _____________________
/S/ GLEN A. PAYNE
SECRETARY
/S/ JOHN J. [ILLEGIBLE]
PRESIDENT

[SEAL]

COUNTERSIGNED AND REGISTERED
BY:  STATE STREET BANK & TRUST COMPANY
     (BOSTON, MASSACHUSETTS)
     TRANSFER AGENT AND REGISTRAR
     ____________________________
     AUTHORIZED SIGNATURE

<PAGE>
                         THE GLOBAL HEALTH SCIENCES FUND

     THE FOLLOWING ABBREVIATIONS, WHEN USED IN THE INSCRIPTION ON THE FACE OF
THIS CERTIFICATE, SHALL BE CONSTRUED AS THOUGH THEY WERE WRITTEN OUT IN FULL
ACCORDING TO APPLICABLE LAWS OR REGULATIONS.

TEN COM  - as tenants in common
TEN ENT  - as tenants by the entireties
JT TEN   - as joint tenants with right of survivorship and not as tenants in
           common
UNIF GIFT MIN ACT - Custodian
                  (Cust)            (Minor)
               under Uniform Gifts to Minors
         Additional abbreviations may also be used though not in the above list.

For value  received,  _________________  hereby sell,  assign and transfer  unto
Please insert Social Security or Other Identifying Number of Assignee
__________________________

________________________________________________________________________________
Please print or typewrite name and address including postal zip code of assignee

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________ Shares
represented by the within Certificate, and do hereby irrevocably constitute and

appoint ________________________________________________________________________
Attorney to transfer the said shares on the books of the within-named Trust with
full power of substitution in the premises.

Dated,  _________________

                              __________________________________________________
     NOTICE:  The signature to this  assignment must correspond with the name as
written  upon  the  face  of  the  Certificate,  in  every  particular,  without
alteration or enlargement or any change whatever.




         THE OFFER EXPIRES AT 5:00 P.M., EASTERN TIME, ON JUNE 18, 1999*
                       INVESCO GLOBAL HEALTH SCIENCES FUND
                 TO SUBSCRIBE FOR SHARES OF BENEFICIAL INTEREST
                            SUBSCRIPTION CERTIFICATE
INVESCO Global Health  Sciences Fund (the "Fund") issued to its  shareholders of
record (the "Record Date Shareholders"),  as of the close of business on May 25,
1999 (the "Record Date"), non-transferable rights ("Rights") on the basis of one
Right for every five whole Shares held on the Record Date,  generally  entitling
the holders  thereof to subscribe for shares of beneficial  interest of the Fund
("Shares")  at a rate of one  Share  for each one  Right  held.  The  terms  and
conditions  of the  rights  offer  (the  "Offer")  are set  forth in the  Fund's
Prospectus, dated May 25, 1999 (the "Prospectus"),  which is incorporated herein
by  reference.  The owner of this  Subscription  Certificate  is entitled to the
number of Rights  shown on this  Subscription  Certificate  and is  entitled  to
subscribe  for the  number of  Shares  shown on this  Subscription  Certificate.
Record Date  Shareholders  who have fully exercised their Rights pursuant to the
Primary Subscription are entitled to subscribe for additional Shares pursuant to
the Over-Subscription  Privilege,  subject to certain limitations and allotment,
as described in the  Prospectus.  Capitalized  terms not defined herein have the
meanings  attributed to them in the Prospectus.  The Fund will not offer or sell
in connection with the Offer any Shares which are not subscribed for pursuant to
the Primary Subscription or the Over-Subscription Privilege.
<TABLE>
<CAPTION>

                               SAMPLE CALCULATION
                FOR A RECORD DATE SHAREHOLDER WHO OWNS 500 SHARES
- -------------------------------------------------------------------------------------------------------------
                   PRIMARY SUBSCRIPTION ENTITLEMENT (1-FOR-5)
<S>                                     <C>           <C>
No. of Shares owned on the Record Date  500 / 5 = 100  Rights (one Right for every five Shares)
No. of Rights issued on the Record Date 100 / 1 = 100  new Shares (if the Rights are fully exercised in the
                                                       Primary Subscription)
- -------------------------------------------------------------------------------------------------------------
</TABLE>

                         THE RIGHTS ARE NON-TRANSFERABLE
The Rights are  non-transferable,  and therefore may not be transferred or sold.
The Rights will not be admitted for trading on the New York Stock  Exchange (the
"NYSE")  or any other  stock  exchange.  The  shares  provided  to  Record  Date
Shareholders  who  exercise  their Rights will be listed for trading on the NYSE
under the symbol "GHS."
                          ESTIMATED SUBSCRIPTION PRICE
The Estimated Subscription Price is ______ per Share.
                            FINAL SUBSCRIPTION PRICE
The Final  Subscription  Price per  Share  will be 95% of the lower of:  (1) the
average of the last reported sales price per Share on the NYSE on the Expiration
Date of the Offer and on the preceding four business days, (i.e., the average of
the closing  prices on the NYSE on June 14, 15, 16, 17, and 18); or (2) the last
reported net asset value per Share on the Expiration Date.
                          METHOD OF EXERCISE OF RIGHTS
IN ORDER TO EXERCISE  YOUR  RIGHTS,  YOU MUST EITHER (i)  COMPLETE AND SIGN THIS
SUBSCRIPTION  CERTIFICATE  ON THE BACK AND  RETURN IT IN THE  ENVELOPE  PROVIDED
TOGETHER  WITH PAYMENT OF AN AMOUNT EQUAL TO THE  ESTIMATED  SUBSCRIPTION  PRICE
MULTIPLIED BY THE TOTAL NUMBER OF SHARES FOR WHICH YOU HAVE  SUBSCRIBED  AND ARE
ISSUED (INCLUDING PURSUANT TO THE OVER-SUBSCRIPTION  PRIVILEGE), OR (ii) PRESENT
A  PROPERLY  COMPLETED  NOTICE OF  GUARANTEED  DELIVERY,  IN EITHER  CASE TO THE
SUBSCRIPTION AGENT, EQUISERVE, INC., BEFORE 5:00 P.M., EASTERN TIME, ON JUNE 18,
1999, OR SUCH LATER DATE AS MAY BE DETERMINED BY THE FUND ("EXPIRATION DATE").

Full  payment  of the  Estimated  Subscription  Price per  Share for all  Shares
subscribed   for   pursuant   to  both   the   Primary   Subscription   and  the
Over-Subscription  Privilege must accompany this  Subscription  Certificate  and
must be made payable in United States dollars by money order or check drawn on a
bank or branch  located  in the United  States  payable to  Equiserve,  Inc.  No
third-party  checks will be accepted.  Because  uncertified  personal checks may
take at least five business days to clear,  we recommend you pay, or arrange for
payment, by means of certified or cashier's check or money order. Alternatively,
if a Notice of  Guaranteed  Delivery is used, a properly  completed and executed
Subscription Certificate, and full payment, as described in such Notice, must be
received by the Subscription Agent no later than 5:00 P.M., Eastern Time, on the
third business day after the Expiration Date, June 23, 1999, unless the offer is
extended by the Fund. For additional information, see the Prospectus.


<PAGE>

Certificates for the Shares acquired  pursuant to both the Primary  Subscription
and the Over-Subscription Privilege will be mailed promptly after the expiration
of the Offer and full payment for the Shares  subscribed  for has been  received
and cleared. Because shareholders must only pay the Estimated Subscription Price
per  Share to  exercise  their  Rights  pursuant  to this  Offer,  and the Final
Subscription Price may be higher or lower than the Estimated  Subscription Price
(and  because  a  shareholder  may not  receive  all the  Shares  for  which  it
subscribes  pursuant  to  the  Over-Subscription  Privilege),  shareholders  may
receive  a refund or be  required  to pay an  additional  amount  equal to:  the
difference  between the Estimated  Subscription Price and the Final Subscription
Price,  multiplied by the total number of Shares for which they have  subscribed
and been issued (including  pursuant to the  Over-Subscription  Privilege).  Any
excess payment to be refunded by the Fund to a shareholder will be mailed by the
Subscription  Agent  to  such  shareholder  as  promptly  as  practicable.   Any
additional  amounts due from  shareholders (in the event the Final  Subscription
Price exceeds the Estimated  Subscription  Price) must be received  within eight
(8) business days after the Confirmation  Date, July 12, 1999,  unless the offer
is extended by the Fund.

*UNLESS EXTENDED BY THE FUND
                                                        Account #:
                                                        Control #:
                                                        CUSIP #:  ___________
                                                        NUMBER OF RIGHTS ISSUED:


<PAGE>

- --------------------------------------------------------------------------------
                PLEASE PRINT ALL INFORMATION CLEARLY AND LEGIBLY
- --------------------------------------------------------------------------------
SECTION 1:  OFFERING INSTRUCTIONS (CHECK THE APPROPRIATE BOXES)

IF YOU WISH TO SUBSCRIBE FOR YOUR FULL ENTITLEMENT:

|_|  I  apply  for  ALL  of my entitlement of new Shares pursuant to the Primary
     Subscription

__________________________    x   $____________   =   $_____________________
(no. of new Shares)           (per share)*

|_|  In addition, I apply for new Shares pursuant to the Over-Subscription
     Privilege**
__________________________    x   $____________   =   $_____________________
(no. of additional Shares)         (per share)*

IF YOU DO NOT WISH TO APPLY FOR YOUR FULL ENTITLEMENT:

|_|  I apply for _____________________   x   $____________   =  $____________
                   (no. of new Shares)        (per share)*
                                  Amount of check enclosed  $_______________.___
IF YOU DO NOT WISH TO EXERCISE YOUR RIGHT TO SUBSCRIBE:
Please disregard this mailing.
- --------------------------------------------------------------------------------
SECTION 2:  SUBSCRIPTION AUTHORIZATION:

         I acknowledge  that I have received the Prospectus for this Offer and I
hereby  irrevocably  subscribe for the number of Shares  indicated  above on the
terms  and  conditions  specified  in the  Prospectus  relating  to the  Primary
Subscription and the Over-Subscription  Privilege. I understand and agree that I
will be obligated to pay an  additional  amount to the Fund if the  Subscription
Price as determined on the Expiration Date is in excess of the $_____  Estimated
Subscription Price per Share.

         I hereby agree that if I fail to pay in full for the Shares for which I
have subscribed,  the Fund may exercise any of the remedies set forth for in the
Prospectus.

Signature of Subscriber(s)
________________________________________________________________________________
(and address if different than that listed on this Subscription  Certificate***)
________________________________________________________________________________

________________________________________________________________________________
Telephone number (including area code)
________________________________________________________________________________
*** If you wish to have your Shares and refund  check (if any)  delivered  to an
address other than that listed on this  Subscription  Certificate  you must have
your signature guaranteed.  Appropriate signature guarantors include:  banks and
savings  associations,  credit  unions,  member  firms of a national  securities
exchange, municipal securities dealers and government securities dealers. Please
provide  the  delivery  address  above  and  note if it is a  permanent  change.
________________________________________________________________________________

SECTION 3: DESIGNATION OF BROKER-DEALER

The following  broker-dealer is hereby designated as having been instrumental in
the exercise of the Rights hereby exercised:
FIRM:_______________________________________________________________
REPRESENTATIVE NAME:________________________________________________
REPRESENTATIVE NUMBER:______________________________________________
________________________________________________________________________________
*        $____ per share is an  estimated  price  only.  The Final  Subscription
         Price will be determined on the Expiration Date, and could be higher or
         lower  depending on any changes in the net asset value and market price
         of the Shares.
**       You can participate in the Over-Subscription Privilege only if you have
         subscribed  for your full  entitlement  of new shares  pursuant  to the
         Primary Subscription.


<PAGE>

         Please complete all applicable information and return to:
                                 EQUISERVE, INC.

<TABLE>
<CAPTION>

<S>                                   <C>                                   <C>
- --------------------------------------------------------------------------------------------------------------------
BY FIRST CLASS MAIL                   BY HAND                               BY EXPRESS MAIL OR OVERNIGHT COURIER
- -------------------                   -------                               ------------------------------------
STATE STREET BANK & TRUST COMPANY     SECURITIES TRANSFER & REPORTING       STATE STREET BANK & TRUST COMPANY
CORPORATE REORGANIZATION              SERVICES, INC.                        CORPORATE REORGANIZATION
P.O. BOX 9573                         100 WILLIAM STREET GALLERIA           40 CAMPANELLI DRIVE
BOSTON, MA 02205-9573                 NEW YORK, NY 10038                    BRAINTREE, MA 02184
U.S.A.                                U.S.A.                                U.S.A.
- --------------------------------------------------------------------------------------------------------------------
</TABLE>

    DELIVERY OF THIS SUBSCRIPTION CERTIFICATE TO AN ADDRESS OTHER THAN AS SET
                FORTH ABOVE DOES NOT CONSTITUTE A VALID DELIVERY.

   ANY QUESTIONS REGARDING THIS SUBSCRIPTION CERTIFICATE AND THE OFFER MAY BE
 DIRECTED TO THE INFORMATION AGENT, SHAREHOLDER COMMUNICATIONS CORPORATION,
                          TOLL FREE AT (800) 722-4072.


<PAGE>

            INSTRUCTIONS FOR COMPLETING THE SUBSCRIPTION CERTIFICATE
                       INVESCO GLOBAL HEALTH SCIENCES FUND

         The  enclosed  Subscription  Certificate  contains the number of Rights
held by the registered holder of such Rights (the "Rights  Holder").  The Rights
Holder has been  issued  one (1) Right for every  five (5) shares of  beneficial
interest ("Share") of the INVESCO Global Health Sciences Fund (the "Fund").  The
Rights  Holder is entitled to acquire one (1) Share for every one (1) Right held
(except  that a Rights  Holder who holds less than one (1) Right is  entitled to
acquire one (1) Share).

         To subscribe  for Shares,  the Rights Holder must present to Equiserve,
Inc.  (the  "Subscription  Agent"),  prior to 5:00 p.m.,  Eastern  time,  on the
Expiration Date, either:

         (1) a properly  completed and executed  Subscription  Certificate and a
         money order or check drawn on a bank or branch of a bank located in the
         United States of America and payable to  EquiServe,  Inc. for an amount
         equal  to the  number  of  Shares  subscribed  for  under  the  Primary
         Subscription  (and,  if such Rights  Holder is electing to exercise the
         Over-Subscription  Privilege,  under the  Over-Subscription  Privilege)
         multiplied by the Estimated Subscription Price; or

         (2) a Notice of  Guaranteed  Delivery  guaranteeing  delivery  of (i) a
         properly  completed and executed  Subscription  Certificate  and (ii) a
         money order or check drawn on a bank or branch of a bank located in the
         United States of America and payable to  EquiServe,  Inc. for an amount
         equal  to the  number  of  Shares  subscribed  for  under  the  Primary
         Subscription  (and,  if such Rights  Holder is electing to exercise the
         Over-Subscription  Privilege,  under the  Over-Subscription  Privilege)
         multiplied by the Estimated  Subscription  Price (which certificate and
         money  order or check  must then be  delivered  on or before  the third
         business day after the Expiration Date).

         If the  Rights  Holder  desires  to  subscribe  for  additional  Shares
pursuant  to the  Over-Subscription  Privilege,  Section  1 of the  Subscription
Certificate must be completed to indicate the maximum number of Shares for which
such  privilege is being  exercised.  A Rights Holder may not receive the entire
number  of Shares  for which it  subscribes  pursuant  to the  Over-Subscription
Privilege.

         On a date within eight (8) business days following the Expiration  Date
(the  "Confirmation  Date"),  June 30, 1999, unless the offer is extended by the
Fund,  subscribers  will be  notified  as to (i) the number of Shares  purchased
under  the  Primary  Subscription  and,  if  applicable,  the  Over-Subscription
Privilege,  and (ii) any additional amount payable by subscribers to the Fund or
any excess to be refunded by the Fund to such  subscribers,  in each case, based
on the Final Subscription Price as determined on the Expiration Date. The Rights
Holder  should  note that the  amount  payable  for the  Shares  subscribed  for
pursuant  to  the  Subscription  Certificate  may be  more  than  the  Estimated
Subscription  Price and that additional  amounts in respect of the  Subscription
Price may be payable  following the  Expiration  Date.  Any  additional  payment
required  from  subscribers  must be received by the  Subscription  Agent within
eight (8) business days after the Confirmation  Date, July 12, 1999,  unless the
offer is extended by the Fund.

         If the Rights Holder does not make timely payment of any amounts due in
respect of Shares  subscribed  for pursuant to the Primary  Subscription  or the
Over-Subscription  Privilege,  the Subscription  Agent and the Fund reserves the
right to (i) sell such  subscribed  and  unpaid-for  Shares to other Record Date
Shareholders,  (ii) apply any payment  actually  received toward the purchase of
the greatest  whole number of Shares that could be acquired by such  shareholder
upon  the  exercise  of  the  Primary   Subscription  and/or   Over-Subscription
Privilege,  and/or (iii)  exercise any and all other rights or remedies to which
the Fund may be entitled.

         Capitalized terms used but not defined in the Subscription  Certificate
shall have the meanings assigned to them in the Prospectus,  dated May 25, 1999,
relating to the Offer.

         ANY QUESTIONS REGARDING THE SUBSCRIPTION  CERTIFICATE AND THE OFFER MAY
BE  DIRECTED  TO  THE  FUND'S  INFORMATION  AGENT,  SHAREHOLDER   COMMUNICATIONS
CORPORATION, TOLL FREE AT (800) 722-4072.

<PAGE>

            INSTRUCTIONS FOR COMPLETING THE SUBSCRIPTION CERTIFICATE
                       INVESCO GLOBAL HEALTH SCIENCES FUND


      The enclosed  Subscription  Certificate contains the number of Rights held
by the registered holder of such Rights (the "Rights Holder"). The Rights Holder
has been issued one (1) Right for every five (5) shares of  beneficial  interest
("Share") of the INVESCO  Global Health  Sciences Fund (the "Fund").  The Rights
Holder is entitled to acquire one (1) Share for every one (1) Right held (except
that a Rights  Holder who holds less than one (1) Right is  entitled  to acquire
one (1) Share).

      To subscribe for Shares, the Rights Holder must present to Equiserve, Inc.
(the "Subscription  Agent"), prior to 5:00 p.m., Eastern time, on the Expiration
Date, either:

      (1) a properly completed and executed Subscription Certificate and a money
      order or check  drawn on a bank or branch of a bank  located in the United
      States of America and payable to  EquiServe,  Inc.  for an amount equal to
      the number of Shares subscribed for under the Primary  Subscription  (and,
      if such  Rights  Holder is  electing  to  exercise  the  Over-Subscription
      Privilege,  under  the  Over-Subscription  Privilege)  multiplied  by  the
      Estimated Subscription Price; or

      (2) a  Notice  of  Guaranteed  Delivery  guaranteeing  delivery  of  (i) a
      properly completed and executed Subscription  Certificate and (ii) a money
      order or check  drawn on a bank or branch of a bank  located in the United
      States of America and payable to  EquiServe,  Inc.  for an amount equal to
      the number of Shares subscribed for under the Primary  Subscription  (and,
      if such  Rights  Holder is  electing  to  exercise  the  Over-Subscription
      Privilege,  under  the  Over-Subscription  Privilege)  multiplied  by  the
      Estimated  Subscription  Price (which certificate and money order or check
      must then be  delivered  on or before  the  third  business  day after the
      Expiration Date).

      If the Rights Holder desires to subscribe for additional  Shares  pursuant
to the Over-Subscription  Privilege,  Section 1 of the Subscription  Certificate
must be  completed  to  indicate  the  maximum  number of Shares  for which such
privilege is being exercised.  A Rights Holder may not receive the entire number
of Shares for which it subscribes pursuant to the Over-Subscription Privilege.

      On a date within eight (8) business  days  following the  Expiration  Date
(the  "Confirmation  Date"),  June 30, 1999, unless the offer is extended by the
Fund,  subscribers  will be  notified  as to (i) the number of Shares  purchased
under  the  Primary  Subscription  and,  if  applicable,  the  Over-Subscription
Privilege,  and (ii) any additional amount payable by subscribers to the Fund or
any excess to be refunded by the Fund to such  subscribers,  in each case, based
on the Final Subscription Price as determined on the Expiration Date. The Rights
Holder  should  note that the  amount  payable  for the  Shares  subscribed  for
pursuant  to  the  Subscription  Certificate  may be  more  than  the  Estimated
Subscription  Price and that additional  amounts in respect of the  Subscription
Price may be payable  following the  Expiration  Date.  Any  additional  payment
required  from  subscribers  must be received by the  Subscription  Agent within
eight  (8) business days after the Confirmation Date, July 12, 1999, unless the
offer is extended by the Fund.

      If the Rights  Holder does not make  timely  payment of any amounts due in
respect of Shares  subscribed  for pursuant to the Primary  Subscription  or the
Over-Subscription  Privilege,  the Subscription  Agent and the Fund reserves the
right to (i) sell such  subscribed  and  unpaid-for  Shares to other Record Date
Shareholders,  (ii) apply any payment  actually  received toward the purchase of
the greatest  whole number of Shares that could be acquired by such  shareholder
upon  the  exercise  of  the  Primary   Subscription  and/or   Over-Subscription
Privilege,  and/or (iii)  exercise any and all other rights or remedies to which
the Fund may be entitled.

      Capitalized  terms used but not  defined in the  Subscription  Certificate
shall have the meanings assigned to them in the Prospectus,  dated May 25, 1999,
relating to the Offer.

      ANY QUESTIONS REGARDING THE SUBSCRIPTION  CERTIFICATE AND THE OFFER MAY BE
DIRECTED   TO  THE  FUND'S   INFORMATION   AGENT,   SHAREHOLDER   COMMUNICATIONS
CORPORATION, TOLL FREE AT (800) 722-4072.




                      FORM OF NOTICE OF GUARANTEED DELIVERY
                      FOR SHARES OF BENEFICIAL INTEREST OF
                       INVESCO GLOBAL HEALTH SCIENCES FUND
                               ------------------

  THIS FORM IS TO BE USED ONLY BY NEW YORK STOCK EXCHANGE MEMBER FIRMS, BANKS,
                OR TRUST COMPANIES, AS NOMINEE HOLDERS OF RIGHTS.
                               -------------------

INVESCO Global Health  Sciences Fund (the "Fund") issued to its  shareholders of
record,  as of the  close of  business  on May 25,  1999  (the  "Record  Date"),
non-transferable  rights  ("Rights")  in the ratio of one  Right for every  five
whole shares held on the Record Date, generally entitling the holders thereof to
subscribe for one share  ("Shares") of beneficial  interest of the Fund for each
Right held.  The terms and  conditions of the rights offer (the "Offer") are set
forth in the Fund's Prospectus, dated May 25, 1999 (the "Prospectus"),  which is
incorporated  herein  by  reference.  As set forth in the  Prospectus  under the
heading  "The  Offer--Payment  for  Shares,"  this  form  or  one  substantially
equivalent  hereto  may be used as a means of  effecting  the  subscription  and
payment for all Shares  subscribed for pursuant to the Primary  Subscription and
the  Over-Subscription  Privilege,  as such terms are defined in the Prospectus.
This form may be delivered by hand or sent by facsimile transmission,  overnight
courier or mail to the Subscription Agent.

                           The Subscription Agent is:

                                 EQUISERVE, INC.
<TABLE>
<CAPTION>

<S>                                   <C>                                    <C>

BY FIRST CLASS MAIL                    BY HAND                                BY EXPRESS MAIL OR OVERNIGHT COURIER
EQUISERVE, INC.                        EQUISERVE, INC.                        EQUISERVE, INC.
C/O STATE STREET BANK & TRUST          C/O SECURITIES TRANSFER & REPORTING    C/O STATE STREET BANK & TRUST
    COMPANY                            SERVICES, INC.                             COMPANY
CORPORATE ACTIONS                      100 WILLIAM STREET GALLERIA            CORPORATE ACTIONS
P.O. BOX 9573                          NEW YORK, NY 10038                     40 CAMPANELLI DRIVE
BOSTON, MA 02205-9573                  U.S.A.                                 BRAINTREE, MA 02184
U.S.A.                                                                          U.S.A.
</TABLE>

                                  BY FACSIMILE
                                 (781) 575-4826

                           CONFIRMED BY TELEPHONE TO:
                                 (781) 575-4816

             DELIVERY OF THIS INSTRUMENT TO AN ADDRESS OTHER THAN AS
              SET FORTH ABOVE DOES NOT CONSTITUTE A VALID DELIVERY.

         The bank,  trust  company or New York Stock  Exchange  member firm,  or
other nominee holder that completes this form must communicate the guarantee and
the number of Shares  subscribed for (pursuant to both the Primary  Subscription
and the Over-Subscription  Privilege) to the Subscription Agent and must deliver
this Notice of Guaranteed Delivery to the Subscription Agent prior to 5:00 p.m.,
Eastern  time,  on the  Expiration  Date,  June 18,  1999,  unless  the offer is
extended.  This  Notice  of  Guaranteed  Delivery  guarantees  delivery  to  the
Subscription  Agent  of  (i) a  properly  completed  and  executed  Subscription
Certificate  and (ii) delivery of payment in full of the Estimated  Subscription
Price for all  subscribed  Shares and payment in full of any  additional  amount
required to be paid if the  Subscription  Price as determined on the  Expiration
Date is in excess of the Estimated  Subscription  Price (which payment,  if any,
must then be delivered no later than the close of business on July 12, 1999, the
eighth  business day after the Confirmation  Date of June 30, 1999,  unless  the
offer is  extended).  Failure to  deliver  this  Notice or to make the  delivery
Guaranteed herein will result in a forfeiture of the Rights.

                                    GUARANTEE

         The  Undersigned,   a  bank  or  trust  company  having  an  office  or
correspondent  in the United States,  or a New York Stock Exchange  member firm,
hereby  guarantees  delivery  to the  Subscription  Agent  of (a) by 5:00  p.m.,
Eastern time on the third business day after the Expiration  Date (i) a properly
completed  and executed  Subscription  Certificate  and (ii) payment of the full
Estimated  Subscription  Price for Shares subscribed for pursuant to the Primary
Subscription  and,  if  applicable,  the  Over-Subscription  Privilege,  as such
subscription for Shares is indicated herein and in the Subscription  Certificate
and (b) by no later than 5:00 p.m., Eastern time, on  July 12, 1999, the  eighth
business day after the Confirmation  Date of June 30, 1999,  unless the offer is
extended, of any additional amount required to be paid if the Subscription Price
as determined on the Expiration Date is in excess of the Estimated  Subscription
Price.

<PAGE>

                                               Broker Assigned Control # _______

                       INVESCO GLOBAL HEALTH SCIENCES FUND

<TABLE>
<CAPTION>

<S>                       <C>                      <C>                                <C>
Primary Subscription      Number of Rights to      Number of Shares subscribed        Payment to be made in
                          be exercised             for pursuant to the Primary        connection with Shares
                                                   Subscription  for  which  you      subscribed for pursuant to
                                                   are guaranteeing delivery          the Primary  Subscription  at
                                                   of Rights and Payment              Estimated Subscription Price.

                          _________Rights   =      _________ Shares                   $___________


Over-Subscription                                  Number of Shares subscribed        Payment to be made in
                                                   for pursuant to the                connection with Shares
                                                   Over-Subscription Privilege        subscribed for pursuant to the
                                                   for which you are                  Over-Subscription Privilege at
                                                   guaranteeing payment               the Estimated Subscription
                                                                                      Price
                                                   _________ Shares                   $___________


Totals                    Total Number of          Total number of Shares             Total Payment
                          Rights to be             requested
                          delivered
                          _________Rights          _________Shares                    $__________
</TABLE>


Method of delivery (circle one)
A.       Through The Depository Trust Company ("DTC")
B.       Direct to Equiserve, Inc., as Subscription Agent. Please indicate below
         how the Rights to be delivered should be registered.

                             -----------------------
                             -----------------------
                             -----------------------


PLEASE ASSIGN A UNIQUE CONTROL NUMBER FOR EACH GUARANTEE SUBMITTED.  This number
needs to be referenced on any direct delivery of Rights or any delivery  through
DTC. In addition, please note that if you are guaranteeing for Shares subscribed
for pursuant to the Over-Subscription  Privilege and are a DTC participant,  you
must  also   execute  and   forward  to   Equiserve,   Inc.  a  Nominee   Holder
Over-Subscription Form.


- ---------------------------------      ----------------------------------------
Name of Firm                           Authorized Signature

- ---------------------------------      ----------------------------------------
DTC Participant Number                 Title

- ---------------------------------      ----------------------------------------
Address                                Name (Please Type or Print)

- ---------------------------------      ----------------------------------------
Zip Code                               Phone Number


- ---------------------------------      ----------------------------------------
Contact Name                           Date


<PAGE>


                   NOTICE OF GUARANTEED DELIVERY INSTRUCTIONS

         A Notice of  Guaranteed  Delivery  may be  submitted  if the  Notice is
received by the Subscription Agent by 5:00 p.m., Eastern Time, on the Expiration
Date or as directed in the Prospectus.

BROKER ASSIGNED CONTROL NUMBER:

         In order to properly track incoming  guarantees on the Expiration Date,
we are  requiring  that each  guarantee  submitted be assigned a unique  control
number.  Each person in the  Reorganization  Department  of a securities  broker
should  assign his or her own unique  number (e.g.  the sixth item  delivered by
Paul in the  Reorganization  Department at XYZ Securities,  could have a control
number of XYZPaul6).  It is the individual firm's  responsibility to ensure that
the control numbers are not duplicated as the firm will be held  responsible for
any losses incurred due to duplication.

ITEM 1.  THE PRIMARY SUBSCRIPTION

         Indicate  the  Rights   exercised   and  Shares   requested   with  the
corresponding  dollar  amount.  Please  note,  by  completing  Item  1  you  are
exercising  Primary  Subscription  Rights.  If the  Rights had  previously  been
exercised through DTC do not complete this portion.

ITEM 2.  THE OVER-SUBSCRIPTION PRIVILEGE

         Indicate the Shares requested and the corresponding dollar amount.

ITEM 3.  TOTALS

         Total the Rights and payment which the Subscription  Agent will receive
from you on the designated dates.

METHOD OF DELIVERY

         Indicate how the Rights will be delivered to the Subscription Agent. If
Subscription  Certificates  are to be  delivered  directly  to the  Subscription
Agent, please provide the registration of such Certificates.



                      NOMINEE HOLDER OVER-SUBSCRIPTION FORM
                       INVESCO GLOBAL HEALTH SCIENCES FUND
                                 RIGHTS OFFERING


         THIS  FORM  IS  TO  BE  USED  ONLY  BY   NOMINEES   TO   EXERCISE   THE
OVER-SUBSCRIPTION  PRIVILEGE,  AS ISSUED BY INVESCO GLOBAL HEALTH  SCIENCES FUND
(THE "FUND"), FOR THE ACCOUNT OR ACCOUNTS OF PERSONS ON WHOSE BEHALF ALL PRIMARY
SUBSCRIPTION  RIGHTS  ("PRIMARY  SUBSCRIPTION  RIGHTS") HAVE BEEN  EXERCISED AND
DELIVERED  THROUGH THE  FACILITIES OF THE DEPOSITORY  TRUST  COMPANY.  ALL OTHER
EXERCISES OF  OVER-SUBSCRIPTION  PRIVILEGES  MUST BE EFFECTED BY THE DELIVERY OF
THE SUBSCRIPTION CERTIFICATES.

                              --------------------

         THE TERMS AND  CONDITIONS  OF THE RIGHTS  OFFERING ARE SET FORTH IN THE
FUND'S PROSPECTUS,  DATED MAY 25, 1999 (THE "PROSPECTUS"),  AND ARE INCORPORATED
HEREIN BY REFERENCE.  COPIES OF THE  PROSPECTUS  ARE AVAILABLE UPON REQUEST FROM
SHAREHOLDER COMMUNICATIONS  CORPORATION,  THE FUND'S INFORMATION AGENT, AT (800)
722-4072.

                              --------------------

         THIS FORM WILL BE DEEMED TO BE VOID UNLESS RECEIVED BY EQUISERVE,  INC.
(THE  "SUBSCRIPTION  AGENT"),  BY 5:00 P.M.,  EASTERN TIME, ON JUNE 18, 1999, OR
SUCH LATER DATE AS MAY BE DETERMINED BY THE FUND (THE "EXPIRATION DATE").

         Please complete all applicable information and return to:
<TABLE>
<CAPTION>

                                 EQUISERVE, INC.

     By First Class Mail:                By Hand:                         By Overnight Courier:
     -------------------                 -------                          --------------------

<S>                                <C>                                   <C>
 State Street Bank & Trust         Securities Transfer & Reporting       State Street Bank & Trust
       Company                            Services, Inc.                          Company
 Corporate Reorganization                 c/o EquiServe                  Corporate Reorganization
     P.O. Box 9573                   100 William Street Galleria            40 Campanelli Drive
 Boston, MA 02205-9573                    New York, NY 10038                Braintree, MA 02184
</TABLE>

                                  By Facsimile:
                                 (781) 575-4826

                           Confirmed by Telephone to:
                                 (781) 575-4816

         1. The undersigned  hereby  certifies to the Fund and the  Subscription
Agent that it is a participant in The Depository  Trust Company ("DTC") and that
it has  either  (i)  exercised  the  Primary  Subscription  Rights  in full  and
delivered such exercised Primary  Subscription  Rights to the Subscription Agent
by  means of  transfer  to the DTC  account  of the  Subscription  Agent or (ii)
delivered to the Subscription  Agent a Notice of Guaranteed  Delivery in respect
of the exercise of the Primary  Subscription  Rights and will deliver the Rights
called for in such Notice of Guaranteed  Delivery to the  Subscription  Agent by
means of transfer to the DTC account of the Subscription Agent.


<PAGE>

         2. The undersigned hereby exercises the Over-Subscription  Privilege to
purchase,  to the extent  available,  ________  shares of  beneficial  ownership
("Shares") of the Fund and certifies to the Fund and the Subscription Agent that
such Over-Subscription  Privilege is being exercised for the account or accounts
of persons  (which may  include  the  undersigned)  on whose  behalf all Primary
Subscription Rights have been exercised.*

         3. The  undersigned  hereby  agrees to make  payment  of the  estimated
subscription price ("Estimated  Subscription Price") of $_________ per share for
each Share  subscribed  for pursuant to the  Over-Subscription  Privilege to the
Subscription  Agent at or before 5:00 p.m., Eastern Time, on the Expiration Date
and hereby represents that (check appropriate box)**:

         [ ]   payment of the final  subscription  price ("Final  Subscription
               Price") will be delivered to the  Subscription  Agent pursuant to
               the  Notice  of  Guaranteed  Delivery  (Broker  Assigned  Control
               #____________);

         [ ]   payment of the Estimated  Subscription Price is being delivered
               to the  Subscription  Agent herewith,  in the aggregate amount of
               $_____________;

         [ ]   payment of the Estimated  Subscription Price has been delivered
               separately to the Subscription  Agent, in the aggregate amount of
               $_____________;

         and,  in the case of  funds  not  delivered  pursuant  to a  Notice  of
Guaranteed  Delivery,  is or was  delivered in the manner set forth below (check
appropriate box and complete information relating thereto):

         |_|      uncertified check

         |_|      certified check

         |_|      bank draft

         ----------------------------------------
         Primary Subscription Confirmation Number


         -----------------------------
         Depository Participant Number


         ------------------------------
         Name of Depository Participant


         * PLEASE  ATTACH A BENEFICIAL  OWNER LISTING  CONTAINING  THE NUMBER OF
RIGHTS OWNED BY EACH  BENEFICIAL  OWNER,  THE NUMBER OF RIGHTS  EXERCISED IN THE
PRIMARY  SUBSCRIPTION  ON BEHALF OF EACH SUCH OWNER AND THE NUMBER OF ADDITIONAL
SHARES REQUESTED ON BEHALF OF EACH SUCH OWNER PURSUANT TO THE  OVER-SUBSCRIPTION
PRIVILEGE.

         ** Because shareholders must only pay the Estimated  Subscription Price
per  Share to  exercise  their  Rights  pursuant  to this  Offer,  and the Final
Subscription Price may be higher or lower than the Estimated  Subscription Price
(and  because  a  shareholder  may not  receive  all the  Shares  for  which  it
subscribes  pursuant  to  the  Over-Subscription  Privilege),  shareholders  may
receive  a refund or be  required  to pay an  additional  amount  equal to:  the
difference  between the Estimated  Subscription Price and the Final Subscription

<PAGE>

Price,  multiplied by the total number of Shares for which they have  subscribed
and been issued (including  pursuant to the  Over-Subscription  Privilege).  Any
excess payment to be refunded by the Fund to a shareholder will be mailed by the
Subscription  Agent  to  such  shareholder  as  promptly  as  practicable.   Any
additional  amounts due from  shareholders (in the event the Final  Subscription
Price exceeds the Estimated  Subscription  Price) must be received  within seven
(7) business days after the Confirmation Date.

         Registration into which Shares and/or refund checks should be issued:

         Name(s): ______________________________________

         Address  ______________________________________

                  ______________________________________


<PAGE>


         Certified TIN:    ______________________________________

         By:      ______________________________________
                  Name:
                  Title:

         Contact Name:     ______________________________________

         Phone Number:     ______________________________________

         Dated:            ________________, 1999




                       INVESCO GLOBAL HEALTH SCIENCES FUND

                     6,081,223 Shares of Beneficial Interest
                Issuable Upon Exercise of Non-Transferable Rights
               to Subscribe for Such Shares of Beneficial Interest


                            DEALER MANAGER AGREEMENT




                                          New York, New York
                                          May 24, 1999


PaineWebber Incorporated
1285 Avenue of the Americas
New York, New York 10019


Ladies and Gentlemen:

     Each of INVESCO Global Health Sciences Fund, a Massachusetts business trust
(the  "Fund"),  and INVESCO  Funds  Group,  Inc.,  a Delaware  corporation  (the
"Investment  Manager"),  hereby  confirms the agreement with and  appointment of
PaineWebber  Incorporated  to act as dealer  manager (the  "Dealer  Manager") in
connection  with  the  issuance  by the  Fund  to the  holders  of  record  (the
"Holders")  of common  shares of  beneficial  interest of the Fund (the  "Common
Shares") at the close of business on the record date set forth in the Prospectus
(as defined herein) (the "Record Date")  non-transferable  rights entitling such
Holders  to  subscribe  for up to  6,081,223  new  shares  (each a "Share"  and,
collectively,  the  "Shares")  of the Common  Shares of the Fund (the  "Offer").
Pursuant  to the  terms  of the  Offer,  the Fund is  issuing  each  Holder  one
non-transferable  right (each a "Right" and,  collectively,  the  "Rights")  for
every five Common  Shares held by such Holder on the Record Date.  The Fund will
issue one Right to Holders  owning  less than five  Common  Shares on the Record
Date. Such Rights entitle Holders to acquire during the subscription  period set
forth in the Prospectus (the "Subscription  Period"),  at the price set forth in
such Prospectus (the "Subscription  Price"),  one Share for each Right exercised
on the terms and conditions set forth in such Prospectus.  No fractional  rights
or shares will be issued.  Any Holder who fully  exercises all Rights  initially
issued to such Holder (other than those Rights that cannot be exercised  because
they  represent  the right to acquire  less than one Share)  will be entitled to
subscribe for, subject to allocation,  additional Shares (the "Over-Subscription
Privilege") on the terms and conditions set forth in the Prospectus. Pursuant to

<PAGE>

the Over-Subscription  Privilege, the Fund may, at its discretion,  increase the
number of Shares subject to subscription by up to 25%, or 1,520,306 Shares,  for
an aggregate total of 7,601,529 Shares.

     The Fund has  filed  with  the  Securities  and  Exchange  Commission  (the
"Commission")  a  registration   statement  on  Form  N-2  (Nos.  333-75831  and
811-06476) and a related  preliminary  prospectus and  preliminary  statement of
additional information under the Investment Company Act of 1940, as amended (the
"Investment  Company  Act"),  the  Securities  Act  of  1933,  as  amended  (the
"Securities  Act"),  and the rules and  regulations of the Commission  under the
Investment Company Act and the Securities Act (the "Rules and Regulations"), and
has filed such  amendments to such  registration  statement on Form N-2, if any,
and  such  amended  preliminary   prospectuses  and  preliminary  statements  of
additional  information  as may have been  required to the date  hereof.  If the
registration  statement has not become  effective,  a further  amendment to such
registration  statement,  including  forms  of  a  final  prospectus  and  final
statement  of  additional  information,  necessary  to permit such  registration
statement  to  become  effective  will  promptly  be filed by the Fund  with the
Commission.   If  the  registration  statement  has  become  effective  and  any
prospectus  or statement  of  additional  information  contained  therein  omits
certain  information at the time of  effectiveness  pursuant to Rule 430A of the
Rules and  Regulations,  a final  prospectus  and final  statement of additional
information  containing such omitted  information  will promptly be filed by the
Fund  with the  Commission  in  accordance  with  Rule  497(h)  of the Rules and
Regulations. The term "Registration Statement" means the registration statement,
as  amended,  at the time it becomes or became  effective,  including  financial
statements and all exhibits and all documents,  if any,  incorporated therein by
reference,  and any  information  deemed to be included  by Rule 430A.  The term
"Prospectus"  means  the final  prospectus  and final  statement  of  additional
information in the forms filed with the Commission pursuant to Rule 497(c), (e),
(h) or (j) of the  Rules  and  Regulations,  as the case may be, as from time to
time amended or supplemented  pursuant to the Securities Act. The Prospectus and
letters  to  beneficial  owners  of  Common  Shares  of the  Fund,  subscription
certificates and other forms used to exercise rights,  brochures,  wrappers, any
letters from the Fund to securities dealers, commercial banks and other nominees
and any newspaper announcements, press releases and other offering materials and
information  that the Fund may use,  approve,  prepare or  authorize  for use in


                                       2
<PAGE>

connection  with the Offer,  are  collectively  referred to  hereinafter  as the
"Offering Materials".

            1.  REPRESENTATIONS AND WARRANTIES.

                  (a) Each of the Fund and the Investment Manager represents and
warrants to, and agrees with,  the Dealer  Manager as of the date hereof,  as of
the date of the  commencement  of the Offer (such  later date being  hereinafter
referred  to as the  "Representation  Date") and as of the  Expiration  Date (as
defined below) that:

                         (i) the Fund  meets  the  requirements  for use of
                    Form N-2 under the  Securities  Act and the  Investment
                    Company Act and the Rules and Regulations.  At the time
                    the Registration Statement became or becomes effective,
                    the  Registration  Statement  did or will  contain  all
                    statements  required to be stated therein in accordance
                    with and did or will  comply in all  material  respects
                    with  the  requirements  of  the  Securities  Act,  the
                    Investment  Company  Act and the Rules and  Regulations
                    and did not or will not contain an untrue  statement of
                    a  material  fact  or omit to  state  a  material  fact
                    required to be stated  therein or necessary to make the
                    statements  therein not  misleading.  From the time the
                    Registration  Statement  became  or  becomes  effective
                    through the  expiration  date of the Offer set forth in
                    the Prospectus (the "Expiration  Date"), the Prospectus
                    and the other  Offering  Materials  will not contain an
                    untrue  statement  of a material  fact or omit to state
                    any  material  fact  required  to be stated  therein or
                    necessary in order to make the statements  therein,  in
                    the light of the  circumstances  under  which they were
                    made,  not  misleading;  PROVIDED,  HOWEVER,  that  the
                    representations and warranties in this subsection shall
                    not apply to statements  relating to the Dealer Manager
                    in,  or  omissions  from  the  Registration  Statement,
                    Prospectus or Offering Materials relating to the Dealer
                    Manager,  made in reliance upon and in conformity  with
                    information  furnished  to the Fund in  writing  by the
                    Dealer  Manager  expressly for use in the  Registration
                    Statement,   Prospectus  or  Offering  Materials,  such
                    information being as set forth in Section 7(h) hereof.

                         (ii)  the  Fund has  been  duly  organized  and is
                    validly  existing as a business trust under the laws of


                                     3
<PAGE>

                    the Commonwealth of  Massachusetts,  has full power and
                    authority  (corporate  and other) to own its properties
                    and  to  conduct  its  business  as  described  in  the
                    Registration  Statement and the  Prospectus,  currently
                    maintains all governmental licenses, permits, consents,
                    orders,     approvals    and    other    authorizations
                    (collectively, the "Licenses and Permits") necessary to
                    carry  on  its   business   as   contemplated   in  the
                    Prospectus,  and is duly  qualified  to do  business in
                    each  jurisdiction  wherein  it  owns  or  leases  real
                    property  or in  which  the  conduct  of  its  business
                    requires such  qualification,  except where the failure
                    to be so  qualified  would  not  result  in a  material
                    adverse  change  to the  Fund's  business,  properties,
                    financial  position or results of operations.  The Fund
                    has no subsidiaries.

                         (iii) the  Fund  is  duly   registered   with  the
                    Commission  under  the  Investment  Company  Act  as  a
                    closed-end,  diversified management investment company,
                    no  order  of   suspension   or   revocation   of  such
                    registration  has been issued or  proceedings  therefor
                    initiated  or,  to the  best of the  Fund's  knowledge,
                    threatened by the  Commission,  all required action has
                    been taken under the  Securities  Act,  the  Investment
                    Company Act to make the public  offering and consummate
                    the issuance of the Rights and the issuance and sale of
                    the Shares by the Fund upon exercise of the Rights, and
                    the  provisions of the Fund's  declaration of trust and
                    by laws comply as to form in all material respects with
                    the requirements of the Investment  Company Act and the
                    rules and regulations thereunder.

                         (iv)  PricewaterhouseCoopers  LLP, the independent
                    accountants who audited the financial statements of the
                    Fund set  forth or  incorporated  by  reference  in the
                    Registration   Statement   and  the   Prospectus,   are
                    independent  public  accountants  as  required  by  the
                    Securities  Act,  the  Investment  Company  Act and the
                    Rules and Regulations.

                         (v) the financial statements of the Fund set forth
                    or  incorporated  by  reference  in  the   Registration
                    Statement  and the  Prospectus  present  fairly  in all
                    material  respects the financial  condition of the Fund
                    as of  the  dates  or  for  the  periods  indicated  in


                                     4
<PAGE>

                    conformity   with   generally    accepted    accounting
                    principles  applied  on a  consistent  basis;  and  the
                    information  set  forth  in the  Prospectus  under  the
                    headings   "Fee  Table"  and   "Financial   Highlights"
                    presents   fairly   in  all   material   respects   the
                    information stated therein.

                        (vi)  the Fund has an authorized  capitalization as
                    set forth in the  Prospectus;  the  outstanding  Common
                    Shares  have  been  duly  authorized  and  are  validly
                    issued,  fully paid and  non-assessable  and conform in
                    all material respects to the description thereof in the
                    Prospectus under the heading  "Description of Shares of
                    Beneficial   Interest";   the  Rights  have  been  duly
                    authorized by all  requisite  action on the part of the
                    Fund for  issuance  pursuant  to the Offer;  the Shares
                    have been duly  authorized by all  requisite  action on
                    the part of the Fund for issuance and sale  pursuant to
                    the terms of the Offer and,  when issued and  delivered
                    by the Fund  pursuant to the terms of the Offer against
                    payment   of  the   consideration   set  forth  in  the
                    Prospectus,  will be  validly  issued,  fully  paid and
                    non-assessable;  the Shares  and the Rights  conform in
                    all  material  respects  to  all  statements   relating
                    thereto  contained in the Registration  Statement,  the
                    Prospectus  and the other Offering  Materials;  and the
                    issuance  of each of the  Rights  and the Shares is not
                    subject to any preemptive rights.

                         (vii)  except  as set  forth  in  the  Prospectus,
                    subsequent  to  the   respective   dates  as  of  which
                    information is given in the Registration  Statement and
                    the  Prospectus,  (A) the  Fund  has not  incurred  any
                    liabilities or  obligations,  direct or contingent,  or
                    entered  into  any  transactions,  other  than  in  the
                    ordinary  course of business,  that are material to the
                    Fund, (B) there has not been any material change in the
                    Common Shares or long-term debt of the Fund, if any, or
                    any  material   adverse  change,   or  any  development
                    involving a prospective material adverse change, in the
                    condition  (financial or other),  business,  prospects,
                    net  worth  or  results  of   operations  of  the  Fund
                    (excluding  fluctuations  in the Fund's net asset value
                    due to investment  activities in the ordinary course of
                    business)  and (C)  there  have  been no  dividends  or
                    distributions paid or declared in respect of the Fund's
                    Common Shares.

                                     5
<PAGE>

                         (viii)  there is no pending  or, to the best of the
                    Fund's knowledge, threatened action, suit or proceeding
                    that may  materially  affect  the Fund or to which  the
                    Fund is a party before or by any court or  governmental
                    agency,  authority or body or any  arbitrator,  whether
                    foreign or domestic, which might result in any material
                    adverse  change in the Fund's  condition  (financial or
                    other),  business  prospects,  net worth or  results of
                    operations,  or which might  materially  and  adversely
                    affect the  properties or assets thereof of a character
                    required to be disclosed in the Registration  Statement
                    or the Prospectus.

                         (ix) there are no  franchises,  contracts or other
                    documents  of the Fund  required to be described in the
                    Registration  Statement  or  the  Prospectus,  or to be
                    filed or  incorporated  by reference as exhibits  which
                    are not described or filed or incorporated by reference
                    therein  as  permitted  by  the  Securities   Act,  the
                    Investment Company Act or the Rules and Regulations.

                         (x)  each of this agreement (the "Agreement"), the
                    Subscription Agency Agreement (the "Subscription Agency
                    Agreement")  dated as of May 24, 1999  between the Fund
                    and EquiServe,  Inc. (the  "Subscription  Agent"),  the
                    Information  Agent  Agreement (the  "Information  Agent
                    Agreement")  dated as of May 24, 1999  between the Fund
                    and Shareholder  Communications Corp. (the "Information
                    Agent"),  the Investment  Management Agreement dated as
                    of February 4, 1988 between the Fund and the Investment
                    Manager (the  "Management  Agreement"),  the  Custodian
                    Agreement dated as of January 23, 1992 between the Fund
                    and  State  Street  Bank  and  Trust  Company   ("State
                    Street")  (the  "Custodian  Agreement"),  the  Transfer
                    Agency and  Service  Agreement  dated as of January 16,
                    1992 between the Fund and State  Street (the  "Transfer
                    Agency  Agreement"),  and the Administration  Agreement
                    between the Fund and the Investment Manager dated as of
                    February 28, 1997 and as amended  November 1, 1998 (the
                    "Administration  Agreement")  (collectively,   all  the
                    foregoing  are the  "Fund  Agreements")  has been  duly
                    authorized, executed and delivered by the Fund; each of
                    the  Fund  Agreements   complies  with  all  applicable
                    provisions  of  the  Investment  Company  Act  and  the
                    Investment Advisers Act

                                     6
<PAGE>

                    of 1940, as amended (the "Advisers  Act") and the rules
                    and  regulations  under such Acts;  and,  assuming  due
                    authorization,  execution  and  delivery  by the  other
                    parties   thereto,   each   of  the   Fund   Agreements
                    constitutes  a legal,  valid,  binding and  enforceable
                    obligation  of the Fund,  subject to the  qualification
                    that  the  enforceability  of  the  Fund's  obligations
                    thereunder  may be limited by  bankruptcy,  insolvency,
                    reorganization,  moratorium  and other  similar laws of
                    general   applicability   relating   to  or   affecting
                    creditors'  rights, and to general principles of equity
                    (regardless of whether  enforceability is considered in
                    a proceeding in equity or at law).

                         (xi) neither the  issuance of the Rights,  nor the
                    issuance and sale of the Shares,  nor the execution and
                    delivery  by the Fund of the Fund  Agreements,  nor the
                    performance  and  consummation by the Fund of any other
                    of the transactions contemplated in the Fund Agreements
                    or any sub-custodial arrangements entered into pursuant
                    to the Custodian Agreement, nor the consummation of the
                    transactions    contemplated    therein   or   in   the
                    Registration Statement nor the fulfillment of the terms
                    thereof  will  conflict  with,  result  in a breach  or
                    violation  of, or  constitute  a default or an event of
                    default under,  or result in the creation or imposition
                    of any lien,  charge or encumbrance upon any properties
                    or assets of the Fund under the declaration of trust or
                    bylaws of the Fund or the terms and  provisions  of any
                    agreement,   indenture,   mortgage,   lease   or  other
                    instrument  to which the Fund is a party or by which it
                    may be bound or to which any of the  property or assets
                    of the Fund is subject,  nor will such action result in
                    any violation of any order,  law, rule or regulation of
                    any  court or  governmental  agency  or  body,  whether
                    foreign or domestic,  having jurisdiction over the Fund
                    or any of its properties.

                         (xii)   no   consent,   approval,   authorization,
                    notification  or order of, or filing with, any court or
                    governmental   agency  or  body,   whether  foreign  or
                    domestic,  is required for the consummation by the Fund
                    of the transactions contemplated by the Fund Agreements

                                     7
<PAGE>

                    or the Registration Statement, except such as have been
                    obtained,  or if the registration  statement filed with
                    respect  to the  Shares  is  not  effective  under  the
                    Securities Act as of the time of execution hereof, such
                    as may be  required  (and shall be obtained as provided
                    in this  Agreement)  under the Investment  Company Act,
                    the Securities Act, and the Securities  Exchange Act of
                    1934, as amended (the "Exchange Act").

                         (xiii)  the Common Shares have been duly listed on
                    the New York Stock Exchange and prior to their issuance
                    the Shares will have been duly  approved  for  listing,
                    subject to official notice of issuance, on the New York
                    Stock Exchange.

                         (xiv)  the Fund  (A) has not  taken,  directly  or
                    indirectly,  any action  designed to cause or to result
                    in, or that has  constituted or which might  reasonably
                    be  expected  to  constitute,   the   stabilization  or
                    manipulation  of the price of any  security of the Fund
                    to facilitate the issuance of the Rights or the sale or
                    resale of the  Shares,  (B) has not since the filing of
                    the Registration  Statement sold, bid for or purchased,
                    or  paid  anyone  any   compensation   for   soliciting
                    purchases of, Common Shares of the Fund (except for the
                    solicitation  of  exercises  of the Rights  pursuant to
                    this  Agreement)  and (C) will not,  until the later of
                    the  expiration of the Rights or the  completion of the
                    distribution     (within    the    meaning    of    the
                    antimanipulation  rules under the Exchange  Act) of the
                    Shares, sell, bid for or purchase,  pay or agree to pay
                    to any person any compensation  for soliciting  another
                    to purchase  any other  securities  of the Fund (except
                    for  the   solicitation  of  the  exercises  of  Rights
                    pursuant to this  Agreement);  PROVIDED THAT any action
                    in connection with the Fund's dividend reinvestment and
                    cash  purchase plan will not be deemed to be within the
                    terms of this Section 1(a)(xiv).

                         (xv) the Fund has  complied  in all  previous  tax
                    years,  and  intends  to direct the  investment  of the
                    proceeds of the offering  described in the Registration
                    Statement  and the  Prospectus  in such a manner  as to
                    continue to comply with the  requirements of Subchapter
                    M of the  Internal  Revenue  Code of 1986,  as  amended
                    ("Subchapter  M of the Code"),  and has  qualified  and


                                     8
<PAGE>

                    intends  to   continue   to  qualify  as  a   regulated
                    investment company under Subchapter M of the Code.

                  (b) The  Investment  Manager  represents  and warrants to, and
agrees with, the Dealer Manager as of the date hereof, as of the  Representation
Date and as of the Expiration Date that:

                    (i) the Investment  Manager has been duly  incorporated
               and is validly  existing as a  corporation  in good standing
               under the laws of the State of Delaware,  has full power and
               authority (corporate and other) to own its properties and to
               conduct  its  business  as  described  in  the  Registration
               Statement  and  the  Prospectus,   currently  maintains  all
               governmental licenses,  permits, consents, orders, approvals
               and other authorizations  necessary to carry on its business
               and  to  enable  the  Investment   Manager  to  continue  to
               supervise  investments in securities as  contemplated in the
               Prospectus,  and  is  duly  qualified  to do  business  as a
               foreign corporation in each jurisdiction  wherein it owns or
               leases real property or in which the conduct of its business
               requires such qualification,  except where the failure to be
               so qualified  would not result in a material  adverse change
               to the Investment Manager's business, properties,  financial
               position or results of operations.

                    (ii) the  Investment  Manager is duly  registered as an
               investment  adviser  under  the  Advisers  Act  and  is  not
               prohibited  by the  Investment  Company Act or the  Advisers
               Act,  or the rules and  regulations  under such  Acts,  from
               acting as an investment adviser for the Fund as contemplated
               in the Prospectus and the Management Agreement.

                    (iii)  each  of  this   Agreement  and  the  Management
               Agreement has been duly  authorized,  executed and delivered
               by the Investment Manager, complies in all material respects
               with all applicable provisions of the Investment Company Act
               and the  Advisers  Act and the rules and  regulations  under
               such Acts, and is, assuming due authorization, execution and
               delivery  by the  other  parties  thereto,  a legal,  valid,
               binding  and   enforceable   obligation  of  the  Investment
               Manager,    subject   to   the   qualification    that   the


                                     9
<PAGE>

               enforceability  of  the  Investment  Manager's   obligations
               thereunder  may  be  limited  by   bankruptcy,   insolvency,
               reorganization, moratorium and other similar laws of general
               applicability  relating to or affecting  creditors'  rights,
               and to general  principles of equity  (regardless of whether
               enforceability is considered in a proceeding in equity or at
               law).

                    (iv)   neither  the   execution   or  delivery  by  the
               Investment  Manager  of  this  Agreement  or the  Management
               Agreement,  nor  the  performance  and  consummation  by the
               Investment  Manager of its obligations  under this Agreement
               or the Management  Agreement,  nor the  consummation  of the
               transactions  contemplated  therein  or in the  Registration
               Statement  nor the  fulfillment  of the terms  thereof  will
               conflict  with,  result  in a breach  or  violation  of,  or
               constitute a default or an event of default under, or result
               in the  creation  or  imposition  of  any  lien,  charge  or
               encumbrance  upon any properties or assets of the Investment
               Manager  under  the  charter  or  bylaws  of the  Investment
               Manager  or the  terms  and  provisions  of  any  agreement,
               indenture,  mortgage, lease or other instrument to which the
               Investment Manager is a party or by which it may be bound or
               to which any of the  property  or  assets of the  Investment
               Manager  is  subject,  nor will  such  action  result in any
               violation of any order, law, rule or regulation of any court
               or governmental agency or body, whether foreign or domestic,
               having  jurisdiction  over the Investment  Manager or any of
               its properties.

                    (v)  there  is no  pending  or,  to  the  best  of  the
               Investment Manager's  knowledge,  threatened action, suit or
               proceeding  affecting the Investment Manager or to which the
               Investment  Manager  is a party  before  or by any  court or
               governmental  agency,  authority or body or any  arbitrator,
               whether foreign or domestic that would materially affect the
               Investment  Manager's  ability  to perform  its  obligations
               under this Agreement or under the Management Agreement.

                    (vi) no consent, approval, authorization,  notification
               or order of, or any filing with,  any court or  governmental
               agency or body, whether foreign or domestic, is required for


                                    10
<PAGE>

               the   consummation   by  the   Investment   Manager  of  the
               transactions   contemplated   by  this   Agreement   or  the
               Management Agreement.

                    (vii)  the  Investment   Manager  (A)  has  not  taken,
               directly or indirectly,  any action  designed to cause or to
               result in, or that has constituted or which might reasonably
               be expected to constitute, the stabilization or manipulation
               of the price of any security of the Fund to  facilitate  the
               issuance  of the Rights or the sale or resale of the Shares,
               (B) has not since the filing of the  Registration  Statement
               sold, bid for or purchased,  or paid anyone any compensation
               for  soliciting  purchases of, Common Shares (except for the
               solicitation   of  exercises  of  Rights  pursuant  to  this
               Agreement)  and  (C)  will  not,  until  the  later  of  the
               expiration   of  the  Rights  or  the   completion   of  the
               distribution  (within  the  meaning of the  antimanipulation
               rules under the Exchange Act) of the Shares,  sell,  bid for
               or purchase, pay or agree to pay any person any compensation
               for soliciting  another to purchase any other  securities of
               the Fund (except for the solicitation of exercises of Rights
               pursuant  to this  Agreement);  PROVIDED  THAT any action in
               connection  with the Fund's dividend  reinvestment  and cash
               purchase  plan will not be deemed to be within  the terms of
               this Section 1(b)(vii).

                  (c) Any certificate  required by this Agreement that is signed
by any  officer of the Fund and the  Investment  Manager  and  delivered  to the
Dealer   Manager  or  counsel  for  the  Dealer   Manager   shall  be  deemed  a
representation and warranty by the Fund and the Investment  Manager, as the case
may be, to the Dealer Manager, as to the matters covered thereby.

            2. AGREEMENT TO ACT AS DEALER MANAGER.

                  (a)  On  the  basis  of  the  representations  and  warranties
contained herein, and subject to the terms and conditions of the Offer:

                    (i) The Fund  hereby  appoints  the Dealer  Manager and
               other soliciting  dealers entering into a Soliciting  Dealer
               Agreement,  in the form  attached  hereto as Exhibit A, with
               the  Dealer  Manager  (the  "Soliciting  Dealers"),  and the


                                    11
<PAGE>

               Dealer  Manager  hereby  agrees to solicit  the  exercise of
               Rights,   in  accordance   with  the  Securities   Act,  the
               Investment  Company  Act  and  the  Exchange  Act,  and  its
               customary practice,  the exercise of the Rights,  subject to
               the terms and conditions of this  Agreement,  the procedures
               described in the Registration Statement, the Prospectus and,
               where   applicable,   the  terms  and   conditions  of  such
               Soliciting Dealer Agreement; and

                    (ii)  The  Fund  agrees  to  furnish,  or  cause  to be
               furnished,  to the Dealer Manager, lists, or copies of those
               lists,  showing  the names and  addresses  of, and number of
               Common  Shares held by,  Holders as of the Record Date,  and
               the Dealer  Manager agrees to use such  information  only in
               connection   with  the  Offer,   and  not  to  furnish   the
               information to any other person except to securities brokers
               and dealers that have been  requested by the Dealer  Manager
               to solicit exercises of Rights.

                  (b) The  Dealer  Manager  agrees to  provide  to the Fund,  in
addition to the services described in paragraph (a) of this Section 2, financial
advisory and marketing  services in connection  with the Offer. No advisory fee,
other  than  the  fees  provided  for in  Section  3 of this  Agreement  and the
reimbursement  of the Dealer  Manager's  out-of-pocket  expenses as described in
Section 5 of this  Agreement,  will be payable by the Fund,  or any other  party
hereto,  to the Dealer  Manager in connection  with the  financial  advisory and
marketing services provided by the Dealer Manager pursuant to this Section 2(b).

                  (c) The Fund and the  Dealer  Manager  agree  that the  Dealer
Manager is an independent  contractor  with respect to the  solicitation  of the
exercise of Rights and the  performance  of  financial  advisory  and  marketing
services for the Fund contemplated by this Agreement.

                  (d) In rendering the services  contemplated by this Agreement,
the  Dealer  Manager  will not be subject  to any  liability  to the Fund or the
Investment  Manager or any of their  affiliates,  for any act or omission on the
part of any  soliciting  broker or dealer  (except  with  respect  to the Dealer
Manager  acting in such  capacity) or any other person,  and the Dealer  Manager
will not be liable for acts or omissions in  performing  its  obligations  under
this Agreement, except for any losses, claims, damages, liabilities and expenses
that are finally judicially  determined by a court of competent  jurisdiction to
have  resulted  primarily  from  the bad  faith,  willful  misconduct  or  gross
negligence  of the  Dealer  Manager or by reason of the  intentional  failure to


                                    12
<PAGE>

perform  substantially  the  obligations  and duties of the Dealer Manager under
this Agreement.

            3. DEALER  MANAGER AND  SOLICITATION  FEES.  In full payment for the
solicitation,  financial  advisory  and  marketing  services  rendered and to be
rendered  hereunder  by the Dealer  Manager,  the Fund  agrees to pay the Dealer
Manager  a fee (the  "Dealer  Manager  Fee")  equal  to  3.75% of the  aggregate
Subscription  Price for the Shares issued pursuant to the exercise of Rights and
the Over-Subscription  Privilege.  In full payment for the soliciting efforts to
be  rendered,  the  Dealer  Manager  agrees to  reallow  solicitation  fees (the
"Solicitation  Fees") to Soliciting  Dealers equal to 2.50% of the  Subscription
Price per Share for each Share issued pursuant to the exercise of Rights and the
Over-Subscription   Privilege.   The  Dealer   Manager  agrees  to  reallow  the
Solicitation Fees to the broker-dealer  designated on the applicable  portion of
the  form  used by the  Holder  to  exercise  Rights  and the  Over-Subscription
Privilege, provided that such broker-dealer has entered into a Soliciting Dealer
Agreement,  and if no  broker-dealer  is so  designated  or a  broker-dealer  is
otherwise  not  entitled  to receive  compensation  pursuant to the terms of the
Soliciting  Dealer  Agreement,   then  the  Dealer  Manager  shall  retain  such
Solicitation  Fees for Shares issued  pursuant to the exercise of Rights and the
Over-Subscription  Privilege.  Payment to the Dealer Manager by the Fund will be
in the form of a wire  transfer  of same day  funds to an  account  or  accounts
identified  by the Dealer  Manager.  Such  payment  will be made on each date on
which the Fund issues Shares after the Expiration Date.  Payment to a Soliciting
Dealer will be made by the Dealer Manager directly to such Soliciting  Dealer by
check to an address identified by such Soliciting Dealer. Such payments shall be
made on or before the tenth  business day following the day of final payment for
Shares as set forth in the Prospectus.

            4.  OTHER AGREEMENTS.

                    (a) The Fund covenants with the Dealer Manager as follows:

                    (i) The Fund  will use its best  efforts  to cause  the
               Registration  Statement to become  effective and to maintain
               its effectiveness  under the Securities Act, and will advise
               the  Dealer  Manager  promptly  as to the time at which  the
               Registration Statement and any amendments thereto (including
               any post-effective amendment) becomes so effective.


                                    13
<PAGE>

                    (ii) The Fund will  notify,  and  confirm the notice in
               writing  to,  the  Dealer  Manager  immediately  (A)  of the
               effectiveness   of  the   Registration   Statement  and  any
               amendment thereto (including any post-effective  amendment),
               (B) of the receipt of any comments from the Commission,  (C)
               of any request by the  Commission  for any  amendment to the
               Registration Statement or any amendment or supplement to the
               Prospectus  or  for  additional  information,   (D)  of  the
               issuance by the Commission of any stop order  suspending the
               effectiveness   of  the   Registration   Statement   or  the
               initiation of any proceedings  for that purpose,  and (E) of
               the  suspension  of the  qualification  of the Shares or the
               Rights for  offering or sale in any  jurisdiction.  The Fund
               will make every reasonable effort to prevent the issuance of
               any stop order described in subsection (D) hereunder and, if
               any such stop order is issued, to obtain the lifting thereof
               at the earliest possible moment.

                    (iii) The Fund will give the Dealer  Manager  notice of
               its  intention  to file any  amendment  to the  Registration
               Statement  (including any  post-effective  amendment) or any
               amendment or supplement  to the  Prospectus  (including  any
               revised  prospectus  which the Fund  proposes for use by the
               Dealer Manager in connection  with the Offer,  which differs
               from the  prospectus  on file at the  Commission at the time
               the Registration Statement becomes effective, whether or not
               such revised  prospectus is required to be filed pursuant to
               Rule  497(c),  (e) or (h) of  the  Rules  and  Regulations),
               whether   pursuant  to  the  Investment   Company  Act,  the
               Securities  Act, or  otherwise,  and will furnish the Dealer
               Manager with copies of any such  amendment  or  supplement a
               reasonable  amount of time prior to such proposed  filing or
               use,  as the  case  may be,  and  will  not  file  any  such
               amendment  or  supplement  to which the  Dealer  Manager  or
               counsel for the Dealer Manager shall reasonably object.

                    (iv) The Fund  will,  without  charge,  deliver  to the
               Dealer Manager, as soon as practicable, the number of copies
               (one of  which is  manually  executed)  of the  Registration
               Statement as originally filed and of each amendment  thereto
               as it may reasonably request, in each case with the exhibits
               filed therewith.

                                    14
<PAGE>

                    (v) The  Fund  will,  without  charge,  furnish  to the
               Dealer Manager, from time to time during the period when the
               Prospectus is required to be delivered  under the Securities
               Act, such number of copies of the  Prospectus (as amended or
               supplemented)  as the Dealer Manager may reasonably  request
               for the purposes  contemplated  by the Securities Act or the
               Rules and Regulations.

                    (vi) If any event  shall  occur as a result of which it
               is necessary,  in the reasonable  opinion of counsel for the
               Dealer  Manager,  to amend or  supplement  the  Registration
               Statement or the  Prospectus in order to make the Prospectus
               not misleading in the light of the circumstances existing at
               the  time  it  is  delivered  to a  Holder,  the  Fund  will
               forthwith  amend or supplement  the  Prospectus by preparing
               and filing with the Commission (and furnishing to the Dealer
               Manager a  reasonable  number of copies of) an  amendment or
               amendments of the Registration  Statement or an amendment or
               amendments  of  or  a  supplement  or   supplements  to  the
               Prospectus  (in form and substance  satisfactory  to counsel
               for the Dealer Manager),  at the Fund's expense,  which will
               amend  or  supplement  the  Registration  Statement  or  the
               Prospectus so that the Prospectus will not contain an untrue
               statement  of a  material  fact or omit to state a  material
               fact required to be stated  therein or necessary in order to
               make  the   statements   therein,   in  the   light  of  the
               circumstances   existing  at  the  time  the  Prospectus  is
               delivered to a Holder, not misleading.

                    (vii) The Fund will  cooperate in  connection  with the
               Dealer  Manager's and its counsel's  endeavor to qualify the
               Rights  and the  Shares  for  offering  and sale  under  the
               applicable   securities   laws  of  such  states  and  other
               jurisdictions of the United States as the Dealer Manager may
               designate   and  cooperate  in  the   maintenance   of  such
               qualifications  in effect  for the  duration  of the  Offer;
               PROVIDED,  HOWEVER,  that the Fund will not be  obligated to
               file any  general  consent  to  service  of  process,  or to
               qualify  as  a  foreign   corporation  or  as  a  dealer  in
               securities  in any  jurisdiction  in  which it is not now so
               qualified. The Fund will file such statements and reports as
               may be  required by the laws of each  jurisdiction  in which


                                    15
<PAGE>

               the  Rights  and the  Shares  have been  qualified  as above
               provided.

                   (viii) The  Fund will make  generally  available  to its
               security  holders as soon as practicable,  but no later than
               60 days after the end of the Fund's  fiscal  semi-annual  or
               fiscal   year-end  period  covered   thereby,   an  earnings
               statement  (which  need not be audited)  (in form  complying
               with the provisions of Rule 158 of the Rules and Regulations
               of  the  Securities  Act)  covering  a  twelve-month  period
               beginning  not later than the first day of the Fund's fiscal
               semi-annual  period next following the "effective"  date (as
               defined in said Rule 158) of the Registration Statement.

                    (ix)  For a period  of 180  days  from the date of this
               Agreement,  the Fund will not,  without the prior consent of
               the Dealer  Manager,  which consent will not be unreasonably
               withheld,  offer or sell,  or enter  into any  agreement  to
               sell, any equity or equity related securities of the Fund or
               securities convertible into such securities,  other than the
               Rights  and the  Shares  and the  Common  Shares  issued  in
               reinvestment of dividends or distributions.

                    (x) The Fund will use the net  proceeds  from the Offer
               as set forth under "Use of Proceeds" in the Prospectus.

                    (xi) The Fund  will use its best  efforts  to cause the
               Shares to be duly  authorized  for  listing  by the New York
               Stock Exchange prior to the time the Shares are issued.

                    (xii) The Fund will use its best  efforts  to  maintain
               its  qualification as a regulated  investment  company under
               Subchapter M of the Code.

                   (xiii) The  Fund will  advise or cause the  Subscription
               Agent to  advise  the  Dealer  Manager  and each  Soliciting
               Dealer  from day to day during  the period of, and  promptly
               after the  termination  of, the  Offer,  as to the names and
               addresses of all Holders exercising Rights, the total number
               of Rights  exercised by each Holder  during the  immediately
               preceding  day,   indicating  the  total  number  of  Rights


                                    16
<PAGE>

               verified to be in proper  form for  exercise,  rejected  for
               exercise and being processed and, for the Dealer Manager and
               each Soliciting  Dealer,  the number of Rights  exercised on
               subscription  certificates  indicating the Dealer Manager or
               such  Soliciting   Dealer,  as  the  case  may  be,  as  the
               broker-dealer with respect to such exercise,  and as to such
               other  information  as the  Dealer  Manager  may  reasonably
               request;  and  will  notify  the  Dealer  Manager  and  each
               Soliciting  Dealer,  not later than 5:00 P.M., New York City
               time, on the first  business day  following  the  Expiration
               Date,  of the total  number of Rights  exercised  and Shares
               related  thereto,  the total number of Rights verified to be
               in proper form for exercise, rejected for exercise and being
               processed  and, for the Dealer  Manager and each  Soliciting
               Dealer,  the  number of  Rights  exercised  on  subscription
               certificates   indicating   the   Dealer   Manager  or  such
               Soliciting  Dealer, as the case may be, as the broker-dealer
               with  respect  to  such  exercise,  and  as  to  such  other
               information as the Dealer Manager may reasonably request.

                  (b) Neither of the Fund nor the Investment  Manager will take,
directly or  indirectly,  any action  designed to cause or to result in, or that
has  constituted  or which  might  reasonably  be expected  to  constitute,  the
stabilization  or  manipulation  of the  price  of any  security  of the Fund to
facilitate  the  issuance  of the  Rights or the sale or  resale of the  Shares;
PROVIDED that any action in connection with the Fund's dividend reinvestment and
cash  purchase  plan will not be deemed to be within the meaning of this Section
4(b).

            5.  PAYMENT OF EXPENSES.

                  (a) The Fund will pay all expenses incident to the performance
of its obligations under this Agreement, including, but not limited to, expenses
relating  to (i) the  printing  and  filing  of the  Registration  Statement  as
originally filed and of each amendment thereto,  (ii) the preparation,  issuance
and delivery of the certificates  for the Shares and  subscription  certificates
relating to the Rights,  (iii) the fees and  disbursements of the Fund's counsel
(including the fees and  disbursements of local counsel) and  accountants,  (iv)
the  qualification  of the  Rights  and  the  Shares  under  securities  laws in
accordance with the provisions of Section 4(a)(vii) of this Agreement, including


                                    17
<PAGE>

filing  fees,  (v) the printing or other  production  and delivery to the Dealer
Manager of copies of the Registration  Statement as originally filed and of each
amendment  thereto  and of the  Prospectus  and any  amendments  or  supplements
thereto,  (vi) the fees and  expenses  incurred  with respect to filing with the
National  Association of Securities  Dealers,  Inc., (vii) the fees and expenses
incurred  in  connection  with the  listing  of the Shares on the New York Stock
Exchange, (viii) the printing or other production, mailing and delivery expenses
incurred in connection  with  Offering  Materials and (ix) the fees and expenses
incurred with respect to the Subscription Agent and Information Agent.

                  (b) In  addition to any fees that may be payable to the Dealer
Manager under this  Agreement,  the Fund agrees to reimburse the Dealer  Manager
upon  request  made from time to time for its  reasonable  expenses  incurred in
connection with its activities  under this  Agreement,  including the reasonable
fees and  disbursements  of its legal  counsel  (excluding  Blue Sky filing fees
which are paid directly by the Fund), in an amount up to $100,000.

                  (c) If this  Agreement is terminated by the Dealer  Manager in
accordance  with the  provisions  of Section 6 or Section  9(a)(i),  9(a)(ii) or
9(a)(iii),  the Fund  agrees to  reimburse  the  Dealer  Manager  for all of its
reasonable  out-of-pocket  expenses  incurred in connection with its performance
hereunder,  including the reasonable fees and  disbursements  of counsel for the
Dealer Manager.  In the event the  transactions  contemplated  hereunder are not
consummated,  the Fund agrees to pay all of the costs and  expenses set forth in
paragraphs  (a) and (b) of this Section 5 which the Fund would have paid if such
transactions had been consummated.

            6. CONDITIONS OF THE DEALER MANAGER'S  OBLIGATIONS.  The obligations
of the Dealer  Manager  hereunder are subject to the accuracy of the  respective
representations  and warranties of the Fund and the Investment Manager contained
herein,  to the  performance  by the Fund and the  Investment  Manager  of their
respective obligations hereunder, and to the following further conditions:

                  (a) The Registration Statement shall have become effective not
later than 5:30 P.M.,  New York City time,  on the Record Date, or at such later
time and date as may be approved by the Dealer  Manager;  the Prospectus and any
amendment or supplement thereto shall have been filed with the Commission in the
manner and within the time period  required by Rule 497(c),  (e), (h) or (j), as


                                    18
<PAGE>

the  case may be,  under  the  Securities  Act;  no stop  order  suspending  the
effectiveness of the Registration  Statement or any amendment thereto shall have
been issued,  and no proceedings  for that purpose shall have been instituted or
threatened  or, to the  knowledge  of the Fund,  the  Investment  Manager or the
Dealer Manager, shall be contemplated by the Commission; and the Fund shall have
complied with any request of the Commission for  additional  information  (to be
included in the Registration Statement, the Prospectus or otherwise).

                  (b) On the  Representation  Date and the Expiration  Date, the
Dealer Manager shall have received:

                         (1)   The    favorable    opinions,    dated   the
                    Representation   Date  and  the  Expiration   Date,  of
                    Kirkpatrick  & Lockhart  LLP,  counsel for the Fund, in
                    form and  substance  satisfactory  to  counsel  for the
                    Dealer Manager to the effect that:

                         (i)  the  Fund  has  been  duly  organized  and is
                    validly  existing as a business trust under the laws of
                    the Commonwealth of  Massachusetts,  has full power and
                    authority  (corporate  and other) to own its properties
                    and  to  conduct  its  business  as  described  in  the
                    Registration  Statement and the  Prospectus,  currently
                    maintains,  to the best knowledge of such counsel,  all
                    Licenses and Permits necessary to carry on its business
                    as contemplated in the Prospectus  (except that counsel
                    need express no opinion as to  securities or "blue sky"
                    laws  of  any  state),  and  is  duly  qualified  to do
                    business in each jurisdiction wherein it owns or leases
                    real  property or in which the conduct of its  business
                    requires such  qualification,  except where the failure
                    to be so  qualified  would  not  result  in a  material
                    adverse  change  to the  Fund's  business,  properties,
                    financial position or results of operations.

                         (ii)  the  Fund  is  duly   registered   with  the
                    Commission  under  the  Investment  Company  Act  as  a
                    closed-end,  diversified management investment company,
                    no  order  of   suspension   or   revocation   of  such
                    registration  has been issued or  proceedings  therefor
                    initiated or, to the best of knowledge of such counsel,
                    threatened by the  Commission,  all required action has
                    been taken under the  Securities Act and the Investment


                                    19
<PAGE>

                    Company Act to make the public  offering and consummate
                    the issuance of the Rights and the issuance and sale of
                    the Shares by the Fund upon exercise of the Rights, and
                    the  provisions of the Fund's  declaration of trust and
                    by laws comply as to form in all material respects with
                    the requirements of the Investment  Company Act and the
                    rules and regulations thereunder.

                         (iii) the Fund's  authorized  capitalization is as
                    set forth in the  Prospectus;  the  outstanding  Common
                    Shares  have  been  duly  authorized  and  are  validly
                    issued,  fully paid and  non-assessable  and conform in
                    all material respects to the description thereof in the
                    Prospectus under the heading  "Description of Shares of
                    Beneficial   Interest";   the  Rights  have  been  duly
                    authorized by all  requisite  action on the part of the
                    Fund for  issuance  pursuant  to the Offer;  the Shares
                    have been duly  authorized by all  requisite  action on
                    the part of the Fund for issuance and sale  pursuant to
                    the terms of the Offer and,  when issued and  delivered
                    by the Fund  pursuant to the terms of the Offer against
                    payment   of  the   consideration   set  forth  in  the
                    Prospectus,  will be  validly  issued,  fully  paid and
                    non-assessable;  the Shares  and the Rights  conform in
                    all  material  respects  to  all  statements   relating
                    thereto  contained in the Registration  Statement,  the
                    Prospectus  and the other Offering  Materials;  and the
                    issuance  of each of the  Rights  and the Shares is not
                    subject to any preemptive rights.

                         (iv) there is no pending or, to the best knowledge
                    of such counsel,  threatened action, suit or proceeding
                    affecting  the  Fund or to  which  the  Fund is a party
                    before  or  by  any  court  or   governmental   agency,
                    authority or body or any arbitrator  which might result
                    in  any  material   adverse  change  in  the  condition
                    (financial or other), business prospects,  net worth or
                    results  of  operations  of the  Fund,  or which  might
                    materially  and  adversely  affect  the  properties  or
                    assets thereof of a character  required to be disclosed
                    in the Registration Statement or the Prospectus.

                         (v) there are no  franchises,  contracts  or other
                    documents  of the Fund  required to be described in the


                                    20
<PAGE>

                    Registration  Statement  or  the  Prospectus,  or to be
                    filed or  incorporated  by reference as exhibits  which
                    are not described or filed or incorporated by reference
                    therein  as  permitted  by  the  Securities   Act,  the
                    Investment Company Act or the Rules and Regulations.

                         (vi)  each of the Fund  Agreements  has been  duly
                    authorized,   executed  and   delivered  by  the  Fund;
                    complies   with  all   applicable   provisions  of  the
                    Investment  Company  Act and the  Advisers  Act and the
                    rules and regulations  under such Acts;  and,  assuming
                    due authorization,  execution and delivery by the other
                    parties   thereto,   each   of  the   Fund   Agreements
                    constitutes  a legal,  valid,  binding and  enforceable
                    obligation  of the Fund,  subject to the  qualification
                    that  the  enforceability  of  the  Fund's  obligations
                    thereunder  may be limited by  bankruptcy,  insolvency,
                    reorganization,  moratorium  or other  similar  laws of
                    general   applicability   relating   to  or   affecting
                    creditors' rights and general principles of equity.

                         (vii) neither the issuance of the Rights,  nor the
                    issuance and sale of the Shares,  nor the execution and
                    delivery  by the Fund of the Fund  Agreements,  nor the
                    performance  and  consummation by the Fund of any other
                    of  the   transactions   contemplated   in   the   Fund
                    Agreements,  nor the  consummation of the  transactions
                    contemplated  therein or in the Registration  Statement
                    nor the  fulfillment of the terms thereof will conflict
                    with, result in a material breach or material violation
                    of, or  constitute  a default  or a  material  event of
                    default under,  or result in the creation or imposition
                    of any material lien,  charge or  encumbrance  upon any
                    properties or assets of the Fund under the  declaration
                    of  trust  or  bylaws  of the  Fund  or the  terms  and
                    provisions  of  any  material   agreement,   indenture,
                    mortgage,  lease or other  instrument to which the Fund
                    is a party or by which it may be bound or to which  any
                    of the  property or assets of the Fund is subject,  nor
                    will such action  result in any  material  violation of
                    any  order,  law,  rule or  regulation  of any court or
                    governmental  agency or body having  jurisdiction  over
                    the Fund or any of its properties.

                         (viii)  no consent,    approval,    authorization,
                    notification  or order of, or filing with, any court or


                                    21
<PAGE>

                    governmental   agency  or  body  is  required  for  the
                    consummation   by  the   Fund   of   the   transactions
                    contemplated by the Fund Agreements or the Registration
                    Statement,  except (A) such as have been  obtained  and
                    (B) such as may be required  under the blue sky laws of
                    any  jurisdiction in connection  with the  transactions
                    contemplated hereby.

                         (ix) the Common  Shares  have been duly  listed on
                    the New York Stock  Exchange  and the Shares  have been
                    duly approved for listing,  subject to official  notice
                    of issuance, on the New York Stock Exchange.

                         (x) the Registration  Statement is effective under
                    the  Securities   Act;  any  required   filing  of  the
                    Prospectus or any supplement  thereto  pursuant to Rule
                    497(c), (e), (h) or (j) required to be made to the date
                    hereof  has been made in the manner and within the time
                    period required by Rule 497(c), (e), (h) or (j), as the
                    case may be; no stop order suspending the effectiveness
                    of the Registration  Statement has been issued,  and no
                    proceedings  for that purpose have been  instituted or,
                    to the best knowledge of such counsel,  threatened; and
                    the  Registration  Statement,  the  Prospectus and each
                    amendment thereof or supplement thereto (other than the
                    financial statements,  schedules, the notes thereto and
                    the  schedules  and  other   financial,   economic  and
                    statistical data contained or incorporated by reference
                    therein or omitted therefrom,  as to which such counsel
                    need  express  no  opinion)  as  to  their   respective
                    effective  or  issue  dates  comply  as to  form in all
                    material  respects with the applicable  requirements of
                    the Securities  Act and the Investment  Company Act and
                    the Rules and Regulations.

                         (xi) the  statements in the  Prospectus  under the
                    headings   "THE   OFFER-Certain   Federal   Income  Tax
                    Consequences of the Offer" and "FEDERAL TAXATION OF THE
                    FUND  AND  ITS   SHAREHOLDERS"   fairly   present   the
                    information disclosed therein in all material respects.

In rendering  such opinion,  such counsel may rely as to matters of fact, to the
extent such counsel deems proper, on certificates of responsible officers of the
Fund, the Investment Manager and public officials.


                                    22
<PAGE>

            Such  counsel  shall  also have  stated  that,  while  they have not
themselves checked the accuracy and completeness of or otherwise  verified,  and
are  not  passing  upon  and  assume  no  responsibility  for  the  accuracy  or
completeness of, the statements  contained in the Registration  Statement or the
Prospectus,  in the course of their review and discussion of the contents of the
Registration Statement and Prospectus with certain officers and employees of the
Fund and its  independent  accountants,  no facts  have come to their  attention
which  cause them to believe  that the  Registration  Statement,  on the date it
became  effective,  contained any untrue statement of a material fact or omitted
to state any material  fact  required to be stated  therein or necessary to make
the statements  contained  therein not misleading or that the Prospectus,  as of
its date and on the Representation  Date or the Expiration Date, as the case may
be,  contained  any untrue  statement of a material fact or omitted to state any
material fact required to be stated  therein or necessary to make the statements
therein,  in the light of the  circumstances  under  which they were  made,  not
misleading  (except that such  counsel need not express any  statement of belief
with  respect to the  financial  statements,  schedules  or other  financial  or
statistical  data included in or incorporated  by reference in the  Registration
Statement, Prospectus or the Offering Materials).

                              (2)   The  favorable  opinions,   dated   the
                    Representation Date and the Expiration Date, of Glen A.
                    Payne, Esq., counsel for the Investment Manager, to the
                    effect that:

                         (i)  the  Investment   Manager   has   been   duly
                    incorporated  and is validly  existing as a corporation
                    in  good  standing  under  the  laws  of the  State  of
                    Delaware,  has full power and authority  (corporate and
                    other)  to  own  its  properties  and  to  conduct  its
                    business as described in the Registration Statement and
                    the Prospectus,  currently  maintains all  governmental
                    licenses,  permits,  consents,  orders,  approvals  and
                    other authorizations necessary to carry on its business
                    and to enable the  Investment  Manager to  continue  to
                    supervise  investments in securities as contemplated in
                    the Prospectus, and is duly qualified to do business as
                    a foreign  corporation in each jurisdiction  wherein it
                    owns or leases real property or in which the conduct of
                    its business requires such qualification,  except where


                                    23
<PAGE>

                    the  failure to be so  qualified  would not result in a
                    material  adverse  change to the  Investment  Manager's
                    business, properties,  financial position or results of
                    operations.

                         (ii) the Investment  Manager is duly registered as
                    an investment adviser under the Advisers Act and is not
                    prohibited  by  the  Investment   Company  Act  or  the
                    Advisers Act, or the rules and  regulations  under such
                    Acts, from acting as an investment adviser for the Fund
                    as  contemplated  in the  Prospectus and the Management
                    Agreement.

                         (iii) each of this  Agreement  and the  Management
                    Agreement  has  been  duly  authorized,   executed  and
                    delivered by the Investment Manager,  complies with all
                    applicable provisions of the Investment Company Act and
                    the  Advisers Act and the rules and  regulations  under
                    such Acts and is, assuming due authorization, execution
                    and  delivery by the other  parties  thereto,  a legal,
                    valid,  binding  and  enforceable   obligation  of  the
                    Investment  Manager,  subject to the qualification that
                    the   enforceability   of  the   Investment   Manager's
                    obligations  thereunder  may be limited by  bankruptcy,
                    insolvency,   reorganization,   moratorium   and  other
                    similar  laws of general  applicability  relating to or
                    affecting  creditors' rights and to general  principles
                    of equity.

                         (iv)  neither the  execution  nor  delivery by the
                    Investment  Manager of this Agreement or the Management
                    Agreement,  nor the performance and consummation by the
                    Investment   Manager  of  its  obligations  under  this
                    Agreement  or  the   Management   Agreement,   nor  the
                    consummation of the transactions  contemplated  therein
                    or in the Registration Statement nor the fulfillment of
                    the terms thereof will materially conflict with, result
                    in a  material  breach  or  material  violation  of, or
                    constitute a default or an event of default  under,  or
                    result  in the  creation  or  imposition  of any  lien,
                    charge or encumbrance  upon any properties or assets of
                    the  Investment  Manager under the charter or bylaws of
                    the  Investment  Manager or the terms and provisions of
                    any material agreement,  indenture,  mortgage, lease or


                                    24
<PAGE>

                    other  instrument to which the Investment  Manager is a
                    party or by  which  it may be bound or to which  any of
                    the  property  or assets of the  Investment  Manager is
                    subject,  nor will such action  result in any violation
                    of any order,  law,  rule or regulation of any court or
                    governmental  agency or body having  jurisdiction  over
                    the Investment Manager or any of its properties.

                         (v) there is no pending or, to the best  knowledge
                    of such counsel,  threatened action, suit or proceeding
                    affecting  the  Investment  Manager  or  to  which  the
                    Investment Manager is a party before or by any court or
                    governmental   agency,   authority   or   body  or  any
                    arbitrator  which might result in any material  adverse
                    change in the Investment Manager's condition (financial
                    or other), business prospects,  net worth or results of
                    operations  or which  might  materially  and  adversely
                    affect the  properties or assets thereof of a character
                    required to be disclosed in the Registration  Statement
                    or Prospectus.

                         (vi)   no   consent,   approval,    authorization,
                    notification or order of, or any filing with, any court
                    or  governmental  agency  or body is  required  for the
                    consummation   by  the   Investment   Manager   of  the
                    transactions  contemplated  by  this  Agreement  or the
                    Management Agreement.

                         (vii) nothing has come to such counsel's attention
                    that would lead them to believe that the description of
                    the Investment  Manager in the Registration  Statement,
                    on the date it became  effective,  contained any untrue
                    statement  of a  material  fact or omitted to state any
                    material  fact   required  to  be  stated   therein  or
                    necessary to make the statements  contained therein not
                    misleading.

                        (viii) nothing has come to such counsel's attention
                    that would lead them to believe that the description of
                    the  Investment  Manager in the  Prospectus,  as of its
                    date and on the  Representation  Date or the Expiration
                    Date,  as  the  case  may  be,   contained  any  untrue
                    statement  of a  material  fact or omitted to state any
                    material  fact   required  to  be  stated   therein  or
                    necessary to make the statements  therein, in the light
                    of the  circumstances  under which they were made,  not
                    misleading.


                                    25
<PAGE>

In rendering  such opinion,  such counsel may rely as to matters of fact, to the
extent such counsel deems proper, on certificates of responsible officers of the
Investment Manager and public officials.

           Such  counsel  shall  also  have  stated  that,  while  they have not
themselves checked the accuracy and completeness of or otherwise  verified,  and
are  not  passing  upon  and  assume  no  responsibility  for  the  accuracy  or
completeness of, the statements  contained in the Registration  Statement or the
Prospectus,  in the course of their review and discussion of the contents of the
Registration Statement and Prospectus with certain officers and employees of the
Fund, the Investment  Manager and their affiliates,  no facts have come to their
attention which cause them to believe that the  Registration  Statement,  on the
date it became  effective,  contained any untrue statement of a material fact or
omitted to state any material fact required to be stated therein or necessary to
make the statements contained therein not misleading or that the Prospectus,  as
of its date and on the  Representation  Date or the Expiration Date, as the case
may be,  contained  any untrue  statement of a material fact or omitted to state
any  material  fact  required  to be stated  therein  or  necessary  to make the
statements  therein,  in the light of the  circumstances  under  which they were
made, not misleading.

                  (c) The Dealer Manager shall have received from Skadden, Arps,
Slate, Meagher & Flom (Illinois),  counsel for the Dealer Manager,  such opinion
or opinions, dated the Representation Date and the Expiration Date, with respect
to the Offer,  the  Registration  Statement,  the  Prospectus  and other related
matters as the  Dealer  Manager  may  reasonably  require,  and the Fund and the
Investment  Manager shall have  furnished to such counsel such documents as they
reasonably request for the purpose of enabling them to pass upon such matters.

                  (d) The  Fund  shall  have  furnished  to the  Dealer  Manager
certificates of the Fund, signed by the President, the Treasurer, the Secretary,
or a Vice  President  of  the  Fund,  dated  the  Representation  Date  and  the
Expiration Date, to the effect that the signer(s) of such certificate  carefully
examined the  Registration  Statement,  the  Prospectus,  any  supplement to the
Prospectus and this Agreement and that, to the best knowledge of such signer(s):

                    (i) the  representations  and warranties of the Fund in
               this Agreement are true and correct in all material respects


                                    26
<PAGE>

               on and as of the Representation Date or the Expiration Date,
               as the case may be,  with the same  effect as if made on the
               Representation  Date or the Expiration Date, as the case may
               be, and the Fund has complied  with all the  agreements  and
               satisfied all the  conditions on its part to be performed or
               satisfied  at or  prior  to the  Representation  Date or the
               Expiration Date, as the case may be;

                    (ii) no stop order suspending the  effectiveness of the
               Registration  Statement  has been issued and no  proceedings
               for that  purpose  have been  instituted  or, to the  Fund's
               knowledge, threatened; and

                    (iii) since the date of the most recent  balance  sheet
               included or  incorporated  by reference  in the  Prospectus,
               there has been no material  adverse  change in the condition
               (financial or other),  earnings,  business,  prospects,  net
               worth  or  results  of  operations  of the  Fund  (excluding
               fluctuations in the Fund's net asset value due to investment
               activities in the ordinary  course of  business),  except as
               set forth in or contemplated in the Prospectus.

                  (e) The Investment  Manager shall have furnished to the Dealer
Manager  certificates of the Investment  Manager,  signed by the President,  the
Treasurer,  the Secretary or a Vice President of the Investment  Manager,  dated
the  Representation  Date  and the  Expiration  Date,  to the  effect  that  the
signer(s)  of  such  certificates  has  read  the  Registration  Statement,  the
Prospectus, any supplement to the Prospectus and this Agreement and, to the best
knowledge  of  such  signer(s),   the  representations  and  warranties  of  the
Investment  Manager  in this  Agreement  are true and  correct  in all  material
respects on and as of the  Representation  Date or the  Expiration  Date, as the
case may be, with the same effect as if made on the  Representation  Date or the
Expiration Date, as the case may be.

                  (f)  PricewaterhouseCoopers  LLP shall have  furnished  to the
Dealer Manager letters,  dated the Representation  Date and the Expiration Date,
in form and  substance  satisfactory  to the Dealer  Manager,  stating in effect
that:

                    (i) they are  independent  accountants  with respect to
               the Fund  within the  meaning  of the  Securities  Act,  the
               Investment Company Act and the Rules and Regulations;


                                    27
<PAGE>

                    (ii) in their opinion, the audited financial statements
               examined by them and included or  incorporated  by reference
               in the  Registration  Statement  comply  as to  form  in all
               material    respects   with   the   applicable    accounting
               requirements  of  the  Securities  Act  and  the  Investment
               Company Act and the respective  Rules and  Regulations  with
               respect to registration statements on Form N-2;

                    (iii) they have  performed  specified  procedures,  not
               constituting an audit in accordance with generally  accepted
               auditing  standards,  including  a  reading  of  the  latest
               available  unaudited  financial  information  of the Fund, a
               reading of the minute  books of the Fund,  and  inquiries of
               officials  of  the  Fund   responsible   for  financial  and
               accounting  matters and on the basis of such  inquiries  and
               procedures  nothing came to their attention that caused them
               to  believe  that at a  specified  date not more  than  five
               business  days  prior  to  the  Representation  Date  or the
               Expiration Date, as the case may be, there was any change in
               the  Common  Shares,  any  decrease  in  net  assets  or any
               increase  in  long-term  debt of the Fund as  compared  with
               amounts  shown in the most  recent  statement  of assets and
               liabilities  included or  incorporated  by  reference in the
               Registration Statement, except as the Registration Statement
               discloses has occurred or may occur, or they shall state any
               specific changes, increases or decreases;

                    (iv)  in  addition  to the  procedures  referred  to in
               clause  (iii)  above,  they  have  compared  certain  dollar
               amounts (or percentages as derived from such dollar amounts)
               and other financial  information regarding the operations of
               the Fund appearing in the Registration Statement, which have
               previously  been  specified by the Dealer  Manager and which
               shall be specified in such letter, and have found such items
               to be in agreement with the accounting and financial records
               of the Fund.

                  (g) Subsequent to the respective dates as of which information
is given in the Registration Statement and the Prospectus,  there shall not have
been (i) any change,  increase or  decrease  specified  in the letter or letters


                                    28
<PAGE>

referred  to in  paragraph  (f) of this  Section 6, or (ii) any  change,  or any
development  involving a  prospective  change,  in or affecting  the business or
properties of the Fund,  the effect of which,  in any case referred to in clause
(i) or (ii) above,  is, in the  reasonable  judgment of the Dealer  Manager,  so
material and adverse as to make it  impractical  or  inadvisable to proceed with
the Offer as contemplated by the Registration Statement and the Prospectus.



                  (h)  Prior  to the  Representation  Date,  the  Fund  and  the
Investment  Manager  shall have  furnished  to the Dealer  Manager  such further
information,  certificates  and documents as the Dealer  Manager may  reasonably
request.

            If any of the conditions  specified in this Section 6 shall not have
been  fulfilled in all material  respects when and as provided in this Agreement
or waived by the Dealer  Manager,  or if any of the  opinions  and  certificates
mentioned  above or  elsewhere  in this  Agreement  shall not be in all material
respects  satisfactory  in form and  substance  to the  Dealer  Manager  and its
counsel,  this Agreement and all obligations of the Dealer Manager hereunder may
be  canceled  at, or at any time  prior to,  the  Expiration  Date by the Dealer
Manager. Notice of such cancellation shall be given to the Fund in writing or by
telephone confirmed in writing.

            7.  INDEMNIFICATION AND CONTRIBUTION.

                  (a) Each of the Fund and the Manager,  jointly and  severally,
will indemnify and hold harmless the Dealer  Manager,  the directors,  officers,
employees and agents of the Dealer Manager and each person, if any, who controls
the Dealer  Manager  within the meaning of Section 15 of the  Securities Act and
Section 20 of the  Exchange  Act from and against  any and all  losses,  claims,
liabilities,  expenses and damages  (including,  but not limited to, any and all
investigative,  legal and other expenses reasonably incurred in connection with,
and any and all amounts paid in  settlement  of, any action,  suit or proceeding
between any of the indemnified  parties and any indemnifying  parties or between
any indemnified party and any third party, or otherwise, or any claim asserted),
as and when incurred to which the Dealer Manager, or any such person, may become
subject under the Securities Act, the Exchange Act, the Investment  Company Act,
the Advisers  Act or other  federal or state  statutory  law or  regulation,  at
common law or otherwise,  insofar as such losses, claims, liabilities,  expenses
or  damages  arise out of or are based on (i) any  untrue  statement  or alleged
untrue statement of a material fact contained in the Registration Statement, the


                                    29
<PAGE>

Prospectus  or  Offering  Materials,  or  any  amendment  or  supplement  to the
Registration  Statement,  the  Prospectus  or  Offering  Materials,  or  in  any
documents  filed  under  the  Exchange  Act and  deemed  to be  incorporated  by
reference into the Registration Statement, the Prospectus, or in any application
or other  document  executed  by or on  behalf  of the Fund or based on  written
information  furnished  by or on behalf of the Fund filed  with the  Commission,
(ii) the omission or alleged  omission to state in such document a material fact
required  to be  stated  in it or  necessary  to make the  statements  in it not
misleading  or (iii) any act or failure to act or any  alleged act or failure to
act by the Dealer Manager in connection  with, or relating in any manner to, the
Rights or the Shares or the offering  contemplated hereby, and which is included
as part of or  referred  to in any loss,  claim,  liability,  expense  or damage
arising  out of or based  upon  matters  covered  by  clause  (i) or (ii)  above
(provided  that  neither  the Fund nor the  Manager  shall be liable  under this
clause  (iii) to the extent it is finally  judicially  determined  by a court of
competent  jurisdiction  that such  loss,  claim,  liability,  expense or damage
resulted directly from any such acts or failures to act undertaken or omitted to
be taken by such Dealer Manager through its bad faith, willful misconduct, gross
negligence or intentional  failure to perform  substantially the obligations and
duties of the Dealer  Manager under this  Agreement);  provided that neither the
Fund nor the  Manager  will be  liable to the  extent  that  such  loss,  claim,
liability,  expense or damage  arises  from the sale of the Shares in the public
offering to any person by the Dealer Manager and is based on an untrue statement
or omission or alleged  untrue  statement or omission made in reliance on and in
conformity with information  relating to the Dealer Manager furnished in writing
to the Fund by the Dealer  Manager  expressly for inclusion in the  Registration
Statement or the Prospectus. This indemnity agreement will be in addition to any
liability that the Fund or the Manager might otherwise have.

                  (b) The Dealer  Manager will  indemnify  and hold harmless the
Fund and the Investment  Manager,  each person, if any, who controls the Fund or
the Investment Manager within the meaning of Section 15 of the Securities Act or
Section 20 of the Exchange Act, each trustee of the Fund and each officer of the
Fund who signs the  Registration  Statement to the same extent as the  foregoing
indemnity from the Fund or the Manager to the Dealer  Manager,  but only insofar
as losses, claims, liabilities, expenses or damages arise out of or are based on
any untrue statement or omission or alleged untrue statement or omission made in
reliance on and in conformity  with  information  relating to the Dealer Manager


                                    30
<PAGE>

furnished in writing to the Fund by the Dealer Manager  expressly for use in the
Registration  Statement or Prospectus,  such  information  being as set forth in
Section 7(h) hereof.  This  indemnity  will be in addition to any liability that
the Dealer Manager might  otherwise  have;  provided,  however,  that in no case
shall the Dealer  Manager be liable or  responsible  for any amount in excess of
the fees and commissions received by the Dealer Manager.

                  (c)  Any  party  that  proposes  to  assert  the  right  to be
indemnified  under  this  Section 7 will,  promptly  after  receipt of notice of
commencement  of any action against such party in respect of which a claim is to
be made against an  indemnifying  party or parties  under this Section 7, notify
each such  indemnifying  party of the  commencement of such action,  enclosing a
copy of all papers served, but the omission to so notify such indemnifying party
will not relieve it from any liability that it may have to any indemnified party
under the foregoing  provision of this Section 7 unless,  and only to the extent
that, such omission results in the forfeiture of substantive  rights or defenses
by the indemnifying party. If any such action is brought against any indemnified
party  and  it  notifies  the  indemnifying  party  of  its  commencement,   the
indemnifying party will be entitled to participate in and, to the extent that it
elects by delivering  written  notice to the  indemnified  party  promptly after
receiving notice of the  commencement of the action from the indemnified  party,
jointly with any other  indemnifying  party  similarly  notified,  to assume the
defense of the action,  with counsel  satisfactory to the indemnified party, and
after  notice  from  the  indemnifying  party  to the  indemnified  party of its
election to assume the defense, the indemnifying party will not be liable to the
indemnified  party for any legal or other expenses  except as provided below and
except for the reasonable  costs of investigation  subsequently  incurred by the
indemnified  party in connection with the defense.  The  indemnified  party will
have the right to  employ  its own  counsel  in any such  action,  but the fees,
disbursements  and other  charges of such counsel will be at the expense of such
indemnified  party unless (1) the employment of counsel by the indemnified party
has been authorized in writing by the  indemnifying  party,  (2) the indemnified
party has reasonably  concluded  (based on the advice of counsel) that there may
be  legal  defenses  available  to it or  other  indemnified  parties  that  are
different from or in addition to those available to the indemnifying party (3) a
conflict  or  potential  conflict  exists  (based on advice  of  counsel  to the
indemnified  party) between the indemnified party and the indemnifying party (in


                                    31
<PAGE>

which case the indemnifying  party will not have the right to direct the defense
of such action on behalf of the indemnified party) or (4) the indemnifying party
has not in fact  employed  counsel to assume the defense of such action within a
reasonable time after  receiving  notice of the  commencement of the action,  in
each of which cases the  reasonable  fees,  disbursements  and other  charges of
counsel  will be at the  expense of the  indemnifying  party or  parties.  It is
understood that the indemnifying  party or parties shall not, in connection with
any proceeding or related  proceedings in the same  jurisdiction,  be liable for
the reasonable fees,  disbursements  and other charges of more than one separate
firm  admitted  to practice  in such  jurisdiction  at any one time for all such
indemnified  party or parties.  All such fees,  disbursements  and other charges
will be reimbursed by the indemnifying  party promptly as they are incurred.  An
indemnifying  party will not be liable for any settlement of any action or claim
effected  without its written  consent (which  consent will not be  unreasonably
withheld).  No  indemnifying  party shall,  without the prior written consent of
each  indemnified  party,  settle or  compromise  or consent to the entry of any
judgment in any pending or threatened  claim,  action or proceeding  relating to
the matters contemplated by this Section 7 (whether or not any indemnified party
is a party thereto),  unless such settlement,  compromise or consent includes an
unconditional  release of each indemnified  party from all liability  arising or
that may arise out of such  claim,  action or  proceeding.  Notwithstanding  any
other provision of this Section 7(c), if at any time an indemnified  party shall
have  requested an  indemnifying  party to reimburse the  indemnified  party for
fees, disbursements and other charges of counsel, such indemnifying party agrees
that it shall be liable for any settlement  effected without its written consent
if (i) such  settlement  is entered into more than 45 days after receipt by such
indemnifying party of the aforesaid request,  (ii) such indemnifying party shall
have received  notice of terms of such settlement at least 30 days prior to such
settlement being entered into and (iii) such  indemnifying  party shall not have
reimbursed such  indemnified  party in accordance with such request prior to the
date of such settlement.

                  (d) In order to provide for just and equitable contribution in
circumstances  in  which  the  indemnification  provided  for in  the  foregoing
paragraph of this Section 7 is applicable  in accordance  with its terms but for
any reason is held to be unavailable  from the Fund,  the Investment  Manager or
the Dealer Manager, the Fund, the Investment Manager and the Dealer Manager will

                                    32
<PAGE>

contribute  to the total  losses,  claims,  liabilities,  expenses  and  damages
(including any investigative,  legal and other expenses  reasonably  incurred in
connection  with,  and any amount paid in  settlement  of, any  action,  suit or
proceeding or any claim asserted,  but after deducting any contribution received
by the Fund and the  Investment  Manager  from  persons  other  than the  Dealer
Manager,  such as persons who control the Fund or the Investment  Manager within
the meaning of the Securities Act or the Exchange Act,  officers of the Fund who
signed the  Registration  Statement  and  trustees of the Fund,  who may also be
liable for  contribution)  to which the Fund,  the  Investment  Manager  and the
Dealer  Manager may be subject in such  proportion  as shall be  appropriate  to
reflect the relative benefits received by the Fund and the Investment Manager on
the one hand and the Dealer Manager on the other. The relative benefits received
by the Fund and the Investment  Manager (treated jointly for this purpose as one
person) on the one hand and the Dealer Manager on the other hand shall be deemed
to be in the same proportion as the total net proceeds from the Offering (before
deducting  expenses) received by the Fund bear to the total fees received by the
Dealer  Manager,  in each case as set forth on the cover page of the Prospectus.
If,  but only if, the  allocation  provided  by the  foregoing  sentence  is not
permitted by applicable  law, the  allocation of  contribution  shall be made in
such  proportion as is  appropriate  to reflect not only such relative  benefits
referred to in the  foregoing  sentence but also the relative  fault of the Fund
and the Investment  Manager  (treated jointly for this purpose as one person) on
the one hand and the  Dealer  Manager  on the  other  hand with  respect  to the
statements or omissions which resulted in such loss, claim,  liability,  expense
or  damage  in  respect  thereof,  as  well  as  any  other  relevant  equitable
considerations with respect to the Offering.  Such relative fault of the parties
shall be  determined  by  reference  to whether  the  untrue or  alleged  untrue
statement  of a material  fact or the  omission  or alleged  omission to state a
material  fact  relates to  information  supplied  by the Fund,  the  Investment
Manager or the Dealer  Manager,  the intent of the  parties  and their  relative
knowledge,  access to  information  and  opportunity  to correct or prevent such
statement or omission.  The Fund, the Investment  Manager and the Dealer Manager
agree that it would not be just and equitable if contributions  pursuant to this
Section 7(d) were to be determined by pro rata allocation or by any other method
of  allocation  which does not take into  account the  equitable  considerations
referred  to herein.  The amount  paid or payable by an  indemnified  party as a
result of the loss,  claim,  liability,  expense or damage, or action in respect
thereof,  referred to above in this Section 7(d) shall be deemed to include, for


                                    33
<PAGE>

purposes of this Section 7(d) any legal or other expenses reasonably incurred by
such  indemnified  party in connection with  investigating or defending any such
action or claim. Notwithstanding the provisions of this Section 7(d), the Dealer
Manager  shall not be  required to  contribute  any amount in excess of the fees
received  by it and no  person  found  guilty  of  fraudulent  misrepresentation
(within the meaning of Section 11(f) of the Securities  Act) will be entitled to
contribution   from  any  person   who  was  not   guilty  of  such   fraudulent
misrepresentation.  For purposes of this Section 7(d), any person who controls a
party to this  Agreement  within the meaning of the Securities Act will have the
same rights to contribution as that party, and each trustee of the Fund and each
officer  of the Fund who signed the  Registration  Statement  will have the same
rights to  contribution  as the  Fund,  subject  in each case to the  provisions
hereof. Any party entitled to contribution,  promptly after receipt of notice of
commencement  of any action  against  such party in respect of which a claim for
contribution  may be made under this  Section  7(d),  will  notify such party or
parties from whom contribution may be sought, but the omission so to notify will
not relieve the party or parties from whom  contribution  may be sought from any
other  obligation  it or they may have under  this  Section  7(d).  Except for a
settlement entered into pursuant to the last sentence of Section 7(c) hereof, no
party  will be liable  for  contribution  with  respect  to any  action or claim
settled  without its written  consent (which  consent shall not be  unreasonably
withheld).

                  (e) The indemnity  and  contribution  agreements  contained in
this  Section  7 and the  representations  and  warranties  of the  Fund and the
Investment  Manager  contained in this Agreement  shall remain  operative and in
full force and effect regardless of (i) any  investigation  made by or on behalf
of the Dealer Manager,  (ii) acceptance of Shares and payment therefore or (iii)
any termination of this Agreement.

                  (f) Notwithstanding any other provisions in this Section 7, no
party shall be entitled to  indemnification or contribution under this Agreement
against any loss, claim, liability,  expense or damage arising by reason of such
person's willful  misfeasance,  bad faith or gross negligence in the performance
of its duties hereunder,  or by reason of such person's  intentional  failure to
perform such person's obligations and duties hereunder.

                  (g) The Fund and the  Investment  Manager  agree to  indemnify
each Soliciting Dealer and controlling persons to the same extent and subject to


                                    34
<PAGE>

the same  conditions  and to the same  agreements,  including  with  respect  to
contribution,  provided for in subsections  7(a),  7(b),  7(c),  7(d), 7(e), and
7(f).

                  (h) The Fund and the Investment  Manager  acknowledge that the
statements  under  the  caption  "THE  OFFER-Distribution  Arrangements"  in the
Prospectus  constitute the only information  furnished in writing to the Fund by
the Dealer Manager  expressly for use in such  document,  and the Dealer Manager
confirms that such statements are correct in all material respects.

            8.  REPRESENTATIONS,  WARRANTIES AND AGREEMENTS TO SURVIVE DELIVERY.
The respective agreements,  representations,  warranties,  indemnities and other
statements of the Fund or its  officers,  of the  Investment  Manager and of the
Dealer Manager set forth in or made pursuant to this Agreement shall survive the
Expiration  Date and will  remain in full force and  effect,  regardless  of any
investigation  made by or on behalf of Dealer  Manager or the Fund or any of the
officers,  directors or controlling persons referred to in Section 7 hereof, and
will survive  delivery of and payment for the Shares pursuant to the Offer.  The
provisions  of  Sections  5  and 7  hereof  shall  survive  the  termination  or
cancellation of this Agreement.

            9.  TERMINATION OF AGREEMENT.

                  (a) This  Agreement  shall be  subject to  termination  in the
absolute  discretion of the Dealer Manager, by notice given to the Fund prior to
the  expiration of the Offer,  if prior to such time (i)  financial,  political,
economic, currency, banking or social conditions in the United States shall have
undergone any material change the effect of which on the financial markets makes
it, in the Dealer  Manager's  judgment,  impracticable or inadvisable to proceed
with the Offer,  (ii) there has occurred any outbreak or material  escalation of
hostilities  or other  calamity  or crisis the effect of which on the  financial
markets  of the  United  States is such as to make it, in the  Dealer  Manager's
judgment,  impracticable or inadvisable to proceed with the Offer, (iii) trading
in the Common Shares shall have been suspended by the Commission or the New York
Stock  Exchange,  (iv)  trading in  securities  generally  on the New York Stock
Exchange shall have been suspended or limited or (v) a banking  moratorium shall
have been declared either by Federal or New York State authorities.

                  (b) If this Agreement is terminated  pursuant to this Section,
such  termination  shall be without  liability  of any party to any other  party
except as provided in Section 5.

                                    35
<PAGE>

            10.  NOTICES.  All  communications  hereunder will be in writing and
effective only on receipt,  and, if sent to the Dealer Manager,  will be mailed,
delivered or  telegraphed  and  confirmed  to  PaineWebber  Incorporated,  Attn:
Corporate Finance  Department,  1285 Avenue of the Americas,  New York, New York
10019;  or if sent to the Fund or the  Investment  Manager  will be  mailed,  or
delivered or  telegraphed  and  confirmed to them at:  INVESCO Funds Group Inc.,
Attn. Glen Payne, 7800 East Union Avenue, Denver, Colorado 80237, Facsimile No.:
(303) 930-6307.

            11.  SUCCESSORS.  This Agreement will inure to the benefit of and be
binding upon the parties hereto and their  respective  successors and will inure
to the benefit of the officers and directors and controlling persons referred to
in  Section  7 hereof,  and no other  person  will have any right or  obligation
hereunder.

            12. APPLICABLE LAW. This Agreement will be governed by and construed
in accordance with the laws of the State of New York.

            13.  COUNTERPARTS.  This  Agreement  may be  executed in one or more
counterparts,  each of which shall be deemed to be an original, but all of which
together shall constitute one and the same instrument.

            14. LIMITATION OF LIABILITY.  Consistent with the Fund's Declaration
of Trust,  notice is hereby given and the parties hereto  acknowledge  and agree
that  this  Agreement  is  executed  on behalf  of the  Trustees  of the Fund as
Trustees and not  individually  and that the  obligations of the Fund under this
Agreement are not binding upon any of the Trustees or  shareholders  of the Fund
individually but are binding only against the assets and property of the Fund.


                                    36
<PAGE>


            If the foregoing is in  accordance  with your  understanding  of our
agreement,  please so indicate  in the space  provided  below for that  purpose,
whereupon this letter shall  constitute a binding  agreement among the Fund, the
Investment Manager and the Dealer Manager.

                              Very truly yours,

                              INVESCO GLOBAL HEALTH SCIENCES FUND

                              By: ____________________________________
                                  Name:
                                  Title:


                              INVESCO FUNDS GROUP, INC.

                              By: ____________________________________
                                  Name:
                                  Title:


The  foregoing  Agreement is hereby  confirmed and accepted as of the date first
above written.

PAINEWEBBER INCORPORATED


By: /s/ Oscar J. Junquera
    ------------------------
    Name:  Oscar J. Junquera
    Title: Managing Director

<PAGE>

                                                            EXHIBIT A

                    INVESCO GLOBAL HEALTH SCIENCES FUND

             Rights Offering for Shares of Beneficial Interest

                        SOLICITING DEALER AGREEMENT

          THE OFFER WILL EXPIRE AT 5:00 P.M., NEW YORK CITY TIME,
                     June 18, 1999. UNLESS EXTENDED


To Securities Dealers and Brokers:

            INVESCO  Global Health  Sciences Fund (the "Fund") is issuing to its
shareholders of record ("Record Date  Shareholders") as of the close of business
on May 25,  1999 (the  "Record  Date")  non-transferable  rights  ("Rights")  to
subscribe  for  an  aggregate  of up  to  6,081,223  shares  (the  "Shares")  of
beneficial  interest,  par value $0.01 per share (the "Common  Shares"),  of the
Fund  upon the terms  and  subject  to the  conditions  set forth in the  Fund's
Prospectus (the "Prospectus") dated May 25, 1999 (the "Offer"). Each such Record
Date  Shareholder  is being  issued one Right for each five full  Common  Shares
owned on the Record Date. The Rights entitle the Record Date Shareholder, during
the Subscription Period (as hereinafter  defined) to acquire at the Subscription
Price (as  hereinafter  defined),  one Share for each Right held in the  primary
subscription.  No fractional Shares will be issued.  The Subscription Price will
be __________________. The Subscription Period will commence on May 25, 1999 and
end on the Expiration  Date.  (With respect to the Offer,  the term  "Expiration
Date" means 5:00 p.m.,  New York City time,  on June 18, 1999,  unless and until
the Fund shall, in its sole  discretion,  have extended the period for which the
Offer is open,  in which event the term  "Expiration  Date" with  respect to the
Offer will mean the latest  time and date on which the Offer,  as so extended by
the Fund,  will  expire.) Any Record Date  Shareholder  who fully  exercises all
Rights  issued to such  shareholder  (other  than those  Rights  that  cannot be
exercised  because they  represent  the right to acquire less than one Share) is
entitled to subscribe  for Shares  which were not  otherwise  subscribed  for by
others on  primary  subscription  (the  "Over-Subscription  Privilege").  Shares
acquired pursuant to the Over-Subscription  Privilege are subject to allocation,
as more fully discussed in the Prospectus.

            For the  duration  of the  Offer,  the Fund has  authorized  and the
Dealer Manager has agreed to reallow Solicitation Fee to any qualified broker or


<PAGE>

dealer  executing a  Soliciting  Dealer  Agreement  who solicits the exercise of
Rights and the Over-Subscription  Privilege in connection with the Offer and who
complies with the  procedures  described  below (a  "Soliciting  Dealer").  Upon
timely delivery to EquiServe, Inc., the Fund's Subscription Agent for the Offer,
of payment  for Shares  purchased  pursuant  to the  exercise  of Rights and the
Over-Subscription Privilege and of properly completed and executed documentation
as set forth in this Soliciting  Dealer  Agreement,  a Soliciting Dealer will be
entitled  to receive  the  Solicitation  Fee equal to 2.50% of the  Subscription
Price per Share so purchased;  provided,  however,  that no payment shall be due
with respect to the issuance of any Shares  until  payment  therefor is actually
received.  A qualified  broker or dealer is a broker or dealer which is a member
of a  registered  national  securities  exchange  in the  United  States  or the
National Association of Securities Dealers,  Inc. ("NASD") or any foreign broker
or dealer not eligible for membership who agrees to conform to the Rules of Fair
Practice of the NASD,  including Sections 2730, 2740, 2420 and 2750 thereof,  in
making  solicitations  in the United  States to the same  extent as if it were a
member thereof.

            The Fund has authorized and the Dealer Manager has agreed to reallow
Solicitation Fee payable to the undersigned  Soliciting  Dealer and the Fund has
agreed to indemnify such Soliciting  Dealer on the terms set forth in the Dealer
Manager  Agreement,  dated May 25, 1999, among  PaineWebber  Incorporated as the
dealer manager (the "Dealer Manager"),  the Fund and others (the "Dealer Manager
Agreement").  Solicitation  and other  activities by  Soliciting  Dealers may be
undertaken only in accordance  with the applicable  rules and regulations of the
Securities  and  Exchange   Commission  and  only  in  those  states  and  other
jurisdictions  where such  solicitations  and other  activities  may lawfully be
undertaken  and in accordance  with the laws thereof.  Compensation  will not be
paid for  solicitations in any state or other  jurisdiction in which the opinion
of counsel to the Fund or counsel to the Dealer Manager,  such  compensation may
not lawfully be paid. No Soliciting  Dealer shall be paid Solicitation Fees with
respect  to  Shares  purchased  pursuant  to  an  exercise  of  Rights  and  the
Over-Subscription  Privilege  for its own  account  or for  the  account  of any
affiliate of the Soliciting Dealer, except that the Dealer Manager shall receive
the Solicitation  Fees with respect to Shares purchased  pursuant to an exercise
of Rights and the Over-Subscription  Privilege for its own account provided that
such  Shares are  offered  and sold by the Dealer  Manager  to its  clients.  No
Soliciting  Dealer or any other person is  authorized  by the Fund or the Dealer
Manager to give any information or make any  representations  in connection with
the Offer other than those  contained  in the  Prospectus  and other  authorized

                                    A-2
<PAGE>

solicitation  material  furnished  by the Fund  through the Dealer  Manager.  No
Soliciting  Dealer  is  authorized  to act as agent  of the  Fund or the  Dealer
Manager in any connection or transaction.  In addition, nothing herein contained
shall constitute the Soliciting Dealers partners with the Dealer Manager or with
one  another,  or agents of the  Dealer  Manager  or of the Fund,  or create any
association between such parties, or shall render the Dealer Manager or the Fund
liable for the obligations of any Soliciting Dealer. The Dealer Manager shall be
under no liability to make any payment to any  Soliciting  Dealer,  and shall be
subject to no other liabilities to any Soliciting  Dealer, and no obligations of
any sort shall be implied.

            In order for a Soliciting Dealer to receive  Solicitation  Fees, the
Subscription  Agent must have received from such Soliciting Dealer no later than
5:00 p.m.,  New York City time, on the  Expiration  Date,  either (i) a properly
completed  and duly  executed  Subscription  Certificate  with respect to Shares
purchased pursuant to the exercise of Rights and the Over-Subscription Privilege
and full  payment  for such  Shares;  or (ii) a Notice  of  Guaranteed  Delivery
guaranteeing  delivery  to the  Subscription  Agent by close of  business on the
third  business  day after the  Expiration  Date,  of (a) full  payment for such
Shares and (b) a properly completed and duly executed  Subscription  Certificate
with  respect  to  Shares   purchased   pursuant  to  the  exercise  of  Rights.
Solicitation Fees will only be paid after receipt by the Subscription Agent of a
properly  completed  and  duly  executed   Soliciting  Dealer  Agreement  and  a
Subscription  Certificate  designating  the Soliciting  Dealer in the applicable
portion  hereof.  In the case of a Notice of Guaranteed  Delivery,  Solicitation
Fees  will  only be paid  after  delivery  in  accordance  with  such  Notice of
Guaranteed  Delivery has been  effected.  Solicitation  Fees will be paid by the
Dealer Manager  (through the  Subscription  Agent) to the  Soliciting  Dealer by
check to an address  designated by the Soliciting  Dealer below on or before the
tenth business day following the day of final payment for Shares as set forth in
the Prospectus.

            All questions as to the form,  validity and  eligibility  (including
time of receipt) of this Soliciting  Dealer  Agreement will be determined by the
Fund, in its sole discretion,  which  determination  shall be final and binding.
Unless  waived,  any  irregularities  in  connection  with a  Soliciting  Dealer
Agreement  or delivery  thereof must be cured within such time as the Fund shall
determine.  None of the Fund, the Dealer Manager,  the  Subscription  Agent, the
Information Agent for the Offer, Shareholder  Communications Corp., or any other
person  will  be  under  any  duty  to  give  notification  of  any  defects  or
irregularities  in any  Soliciting  Dealer  Agreement or incur any liability for
failure to give such notification.

                                    A-3
<PAGE>


            The acceptance of Solicitation Fees from the Fund by the undersigned
Soliciting Dealer shall constitute a representation by such Soliciting Dealer to
the  Fund  that:  (i) it has  received  and  reviewed  the  Prospectus;  (ii) in
soliciting  purchases  of Shares  pursuant to the exercise of the Rights and the
Over-Subscription Privilege, it has complied with the applicable requirements of
the  Securities  Exchange Act of 1934,  as amended  (the  "Exchange  Act"),  the
applicable rules and regulations  thereunder,  any applicable securities laws of
any state or jurisdiction where such solicitations were made, and the applicable
rules and regulations of any self-regulatory organization or registered national
securities  exchange;  (iii) in soliciting  purchases of Shares  pursuant to the
exercise  of  the  Rights  and  the  Over-Subscription  Privilege,  it  has  not
published, circulated or used any soliciting materials other than the Prospectus
and any other authorized solicitation material furnished by the Fund through the
Dealer  Manager;  (iv) it has not  purported  to act as agent of the Fund or the
Dealer Manager in any connection or transaction  relating to the Offer;  (v) the
information  contained  in this  Soliciting  Dealer  Agreement  is,  to its best
knowledge,  true and complete; (vi) it is not affiliated with the Fund; (vii) it
will not accept  Solicitation Fees paid by the Fund pursuant to the terms hereof
with  respect  to Shares  purchased  by the  Soliciting  Dealer  pursuant  to an
exercise  of Rights and the  Over-Subscription  Privilege  for its own  account;
(viii) it will not remit, directly or indirectly,  any part of Solicitation Fees
paid by the Fund pursuant to the terms hereof to any beneficial  owner of Shares
purchased  pursuant  to the  Offer;  (ix) it has  agreed  to the  amount  of the
Solicitation  Fees and the terms and conditions set forth herein with respect to
receiving such  Solicitation  Fees, and (x) it will not engage in short sales of
the Common Shares during the Offering Period.  By returning a Soliciting  Dealer
Agreement and accepting Solicitation Fees, a Soliciting Dealer will be deemed to
have agreed to indemnify the Fund and the Dealer Manager against losses, claims,
damages and  liabilities to which the Fund may become subject as a result of the
breach of such  Soliciting  Dealer's  representations  made herein and described
above. In making the foregoing representations,  Soliciting Dealers are reminded
of the possible  applicability of the antimanipulation  rules under the Exchange
Act if they have  bought,  sold,  dealt in or traded in any Shares for their own
account since the commencement of the Offer.

            Upon expiration of the Offer,  no Solicitation  Fees will be payable
to Soliciting Dealers with respect to Shares purchased thereafter.


                                    A-4
<PAGE>

            Capitalized  terms  not  otherwise  defined  herein  shall  have the
meanings  ascribed to them in the Dealer  Manager  Agreement  or, if not defined
therein, in the Prospectus.

            This Soliciting Dealer Agreement will be governed by the laws of the
State of New York.

            Please execute this Soliciting  Dealer Agreement below accepting the
terms and  conditions  hereof and  confirming  that you are a member firm of the
NASD or a foreign broker or dealer not eligible for membership who has conformed
to the Rules of Fair Practice of the NASD,  including  Sections 2730, 2740, 2420
and 2750 thereof, in making  solicitations of the type being undertaken pursuant
to the Offer in the  United  States  to the same  extent as if you were a member
thereof,  and  certifying  that you have  solicited  the  purchase of the Shares
pursuant to exercise of the Rights,  all as described  above, in accordance with
the terms and conditions set forth in this Soliciting Dealer  Agreement.  Please
forward two executed copies of this Soliciting  Dealer  Agreement to PaineWebber
Incorporated,  Attn: Jose Aldeanueva,  1285 Avenue of the Americas, New York, NY
10019; (Tel. No.: (212) 713-3343  Facsimile No.: (212) 713-4205).  A signed copy
of this Soliciting  Dealer Agreement will be promptly returned to the Soliciting
Dealer at the address set forth below.

                                        Very truly yours,

                                        PaineWebber Incorporated


                                        By: _________________________________
                                            Name:
                                            Title:


PLEASE COMPLETE THE INFORMATION BELOW

__________________________________   ________________________________________
Printed Firm Name                    Address

_____________________________________________________________________________
Contact at Soliciting Dealer

__________________________________   ________________________________________
Authorized Signature                 Area Code and Telephone Number



                                    A-5
<PAGE>

__________________________________   ________________________________________
Name and Title                       Facsimile Number


Dated: ___________________________


Payment of the Solicitation Fee
shall be mailed by check to the
following address:

                         __________________________________

                         __________________________________

                         __________________________________


                          SUBSCRIPTION AGENT AGREEMENT

      This Subscription Agent Agreement (the "Agreement") is made as of May __,
1999 between INVESCO Global Health Sciences Fund (the "Fund") and State Street
Bank and Trust Fund as subscription agent (the "Agent"). All terms not defined
herein shall have the meaning given in the prospectus (the "Prospectus")
included in the (Registration Statement on Form N-2 (File No. 811-06476) filed
by the Fund with the Securities and Exchange Commission on April 7, 1999, as
amended by any amendment filed with respect thereto (the "Registration
Statement").

      WHEREAS, the Fund proposes to make a subscription offer by issuing
certificates or other evidences of subscription rights, in the form designated
by the Fund (the "Subscription Certificates") to shareholders of record (the
"Shareholders") of its shares of beneficial interest, par value $0.01 per share
("Shares"), as of a record date specified by the Fund (the "Record Date"),
pursuant to which each Shareholder will have certain rights (the "Rights") to
subscribe for Shares, as described in and upon such terms as are set forth in
the Prospectus, a final copy of which has been or, upon availability will
promptly be, delivered to the Agent; and

      WHEREAS, the Fund wishes the Agent to perform certain acts on behalf of
the Fund, and the Agent is willing to so act, in connection with the
distribution of the Subscription Certificates and the issuance and exercise of
the Rights to subscribe therein set forth, all upon the terms and conditions set
forth herein.

      NOW, THEREFORE, in consideration of the foregoing and of the mutual
agreements set forth herein, the parties agree as follows:

1.    Appointment. The Fund hereby appoints the Agent to act as subscription
agent in connection with the distribution of Subscription Certificates and the
issuance and exercise of the Rights in accordance with the terms set forth in
this Agreement and the Agent hereby accepts such appointment.

2.    Form and Execution of Subscription Certificates.

      (a) Each Subscription Certificate shall be irrevocable and
non-transferable. The Agent shall, in its capacity as Transfer Agent of the
Fund, maintain a register of Subscription Certificates and the holders of record
thereof (each of whom shall be deemed a "Shareholder" hereunder for purposes of
determining the rights of holders of Subscription Certificates). Each
Subscription Certificate shall, subject to the provisions thereof, entitle the
Shareholder in whose name it is recorded to the following:

            (1) With respect to Record Date Shareholders only, the right to
acquire during the Subscription Period, as defined in the Prospectus, at the
Subscription Price, as defined in the Prospectus, a number of shares of Shares
equal to one share of Shares for every one Right (the "Primary Subscription
Right"); and

            (2) With respect to Record Date Shareholders only, the right to
subscribe for additional Shares, subject to the availability of such Shares and
to the allotment of such Shares as may be available among Record Date
Shareholders who exercise Over-Subscription Rights on the basis specified in the
Prospectus; provided, however, that such Record Date Shareholder has exercised
all Primary Subscription Rights issued to him or her (the "Over-Subscription
Privilege").

3.    Rights and Issuance of Subscription Certificates.

      (a) Each Subscription Certificate shall evidence the Rights of the
Shareholder therein named to purchase Shares upon the terms and conditions
therein and herein set forth.



<PAGE>

      (b) Upon the written advice of the Fund, signed by any of its duly
authorized officers, as to the Record Date, the Agent shall, from a list of the
Fund Shareholders as of the Record Date to be prepared by the Agent in its
capacity as Transfer Agent of the Fund, prepare and record Subscription
Certificates in the names of the Shareholders, setting forth the number of
Rights to subscribe for the Fund's Shares calculated on the basis of one Right
for five shares of Shares recorded on the books in the name of each such
Shareholder as of the Record Date. The number of Rights that are issued to
Record Date Shareholders will be rounded down, by the Agent, to the nearest
number of Full Rights as Fractional Rights will not be issued. Each Subscription
Certificate shall be dated as of the Record Date and shall be executed manually
or by facsimile signature of a duly authorized officer of the Subscription
Agent. Upon the written advice, signed as aforesaid, as to the effective date of
the Registration Statement, the Agent shall promptly countersign and deliver the
Subscription Certificates, together with a copy of the Prospectus, instruction
letter and any other document as the Fund deems necessary or appropriate, to all
Shareholders with record addresses in the United States (including its
territories and possessions and the District of Columbia). Delivery shall be by
first class mail (without registration or insurance), except for those
Shareholders having a registered address outside the United States (who will
only receive copies of the Prospectus, instruction letter and other documents as
the Fund deems necessary or appropriate, if any), delivery shall be by air mail
(without registration or insurance) and by first class mail (without
registration or insurance) to those Shareholders having APO or FPO addresses. No
Subscription Certificate shall be valid for any purpose unless so executed.

      (c) The Agent will mail a copy of the Prospectus, instruction letter, a
special notice and other documents as the Fund deems necessary or appropriate,
if any, but not Subscription Certificates to Record Date Shareholders whose
record addresses are outside the United States (including its territories and
possessions and the District of Columbia ) ("Foreign Record Date Shareholders").
The Rights to which such Subscription Certificates relate will be held by the
Agent for such Foreign Record Date Shareholders' accounts until instructions are
received to exercise the Rights.

4.    Exercise.

      (a) Record Date Shareholders may acquire Shares offered in the Primary
Subscription and pursuant to the Over-Subscription Privilege by delivery to the
Agent, as specified in the Prospectus, of (i) the Subscription Certificate with
respect thereto, duly executed by such Shareholder in accordance with and as
provided by the terms and conditions of the Subscription Certificate, together
with (ii) the estimated purchase price, of as disclosed in the Prospectus, for
each Share subscribed for by exercise of such Rights, in U.S. dollars by money
order or check drawn on a bank in the United States, in each case payable to the
order of the Fund or the Agent.

      (b) Rights may be exercised at any time after the date of issuance of the
Subscription Certificates with respect thereto but no later than 5:00 P.M. New
York time on such date as the Fund shall designate to the Agent in writing (the
"Expiration Date"). For the purpose of determining the time of the exercise of
any Rights, delivery of any material to the Agent shall be deemed to occur when
such materials are received at the Shareholder Services Division of the Agent
specified in the Prospectus.

      (c) Notwithstanding the provisions of Section 4 (a) and 4 (b) regarding
delivery of an executed Subscription Certificate to the Agent prior to 5:00 P.M.
New York time on the Expiration Date, if prior to such time the Agent receives a
Notice of Guaranteed Delivery by facsimile (telecopy) or otherwise from a bank,
a trust Fund or a New York Stock Exchange member guaranteeing delivery of (i)
payment of the full Subscription Price for the shares of Shares subscribed for
on Primary Subscription and any additional shares of Shares subscribed for
pursuant to the Over-Subscription Privilege, and (ii) a properly completed and
executed Subscription Certificate, then such exercise of Primary Subscription


<PAGE>

Rights and Over-Subscription Rights shall be regarded as timely, subject,
however, to receipt of the duly executed Subscription Certificate and full
payment for the Shares by the Agent within three Business Days (as defined
below) after the Expiration Date (the "Protect Period") and full payment for
their Shares within ten Business Days after the Confirmation Date (as defined in
Section 4(d)). For the purposes of the Prospectus and this Agreement, "Business
Day" shall mean any day on which trading is conducted on the New York Stock
Exchange.

      (d) The Fund will determine the Subscription Price by taking the lower of
95% of (i) the average of the last reported sale prices of shares of Shares on
the New York Stock Exchange on the Expiration Date (the "Pricing Date") and the
four Business Days prior thereto, or (ii) the NAV on the Pricing Date. As soon
as practicable, but no later than eight Business Days following the Pricing Date
(the "Confirm Date"), the Agent shall send to each exercising shareholder (or,
if Shares on the Record Date are held by Cede & Co. or any other depository or
nominee, to Cede & Co. or such other depository or nominee) a confirmation
showing the number of Shares acquired pursuant to the Primary Subscription, and,
if applicable, the Over-Subscription Privilege, the per Share and total purchase
price for such Shares, and any additional amount payable to the Fund by such
Shareholder or any excess to be refunded by the Fund to such Shareholder in the
form of a check and stub, along with a letter explaining the allocation of
Shares pursuant to the Over-Subscription Privilege.

      (e) Any additional payment required from a Shareholder must be received by
the Agent within ten Business Days after the Confirmation Date and any excess
payment to be refunded by the Fund to a shareholder will be mailed by the Agent
within seven Business Days after the Confirmation Date. If a Shareholder does
not make timely payment of any additional amounts due in accordance with Section
4(d), the Agent will consult with the Fund in accordance with Section 5 as to
the appropriate action to be taken. The Agent will not issue or deliver
certificates for Shares subscribed for until payment in full therefore has been
received, including collection of checks and payment pursuant to notices of
guaranteed delivery.

5.    Validity of Subscriptions.  Irregular subscriptions not otherwise covered
by specific instructions herein shall be submitted to an appropriate officer of
the Fund and handled in accordance with his or her instructions.  Such
instructions will be documented by the Agent indicating the instructing officer
and the date thereof.

6.    Over-Subscription. If, after allocation of Shares to Record Date
Shareholders, there remain unexercised Rights, then the Agent shall allot the
shares issuable upon exercise of such unexercised Rights (the "Remaining
Shares") to Shareholders who have exercised all the Rights initially issued to
them and who wish to acquire more than the number of Shares for which the Rights
issued to them are exercisable. Shares subscribed for pursuant to the
Over-Subscription Privilege will be allocated in the amounts of such
over-subscriptions. If the number of shares for which the Over-Subscription
Privilege has been exercised is greater than the Remaining Shares, the Agent
shall allocate the Remaining Shares to Record Date Shareholders exercising
Over-Subscription Privilege in a PRO RATE manner based on the number of Shares
owned by them on the Record Date. The percentage of Remaining Shares each
over-subscribing Shareholder may acquire will be rounded up or down to result in
delivery of whole Shares. The Agent shall advise the Fund immediately upon the
completion of the allocation set forth above as to the total number of Shares
subscribed and distributable.

7.    Delivery of Certificates. The Agent will deliver (i) certificates
representing those Shares purchased pursuant to exercise of Primary Subscription
Rights as soon as practicable after the corresponding Rights have been validly
exercised and full payment for such shares has been received and cleared based
on the Estimated Subscription Price and (ii) certificates representing those
Shares purchased pursuant to the exercise of the Over-Subscription Privilege as


<PAGE>

soon as practicable after the Expiration Date and after all allocations have
been effected.

8.    Holding Proceeds of Rights Offering

      (a) All proceeds received by the Agent from Shareholders in respect of the
exercise of Rights shall be held by the Agent, on behalf of the Fund, in a
segregated interest bearing account (the "Account"). All interest that accrues
in the Account pending disbursement in the manner described in Section 4(e)
above will inure to the benefit of the Fund.

      (b) The Agent shall deliver all proceeds received in respect of the
exercise of Rights to the Fund as promptly as practicable, but in no event later
than ten business days after the Confirmation Date. Proceeds held in respect of
Excess Payments (including interest earned thereon) shall belong to the Fund.

9.    Reports.

      (a) Daily, during the period commencing not less than seven (7) business
days prior to the Expiration Date and until termination of the Subscription
Period, the Agent will report by telephone or telecopier (by 2:00 p.m., New York
time), confirmed by letter, to an Officer of the Fund and an Officer of the
PaineWebber Incorporated, data regarding Rights exercised, the total number of
Shares subscribed for, and payments received therefor, bringing forward the
figures from the previous day's report in each case so as to show the cumulative
totals and any such other information as may be mutually determined by the Fund
and the Agent.

10.   Loss or Mutilation. If any Subscription Certificate is lost, stolen,
mutilated or destroyed, the Agent may, on such terms which will indemnify and
protect the Fund and the Agent may in its discretion impose (which shall, in the
case of a mutilated Subscription Certificate include the surrender and
cancellation thereof), issue a new Subscription Certificate of like denomination
in substitution for the Subscription Certificate so lost, stolen, mutilated or
destroyed.

11.   Compensation for Services. The Fund agrees to pay to the Agent
compensation for its services as such in accordance with its Fee Schedule to act
as Agent, dated May 10, 1999 and set forth attached hereto as Exhibit A. The
Fund further agrees that it will reimburse the Agent for its reasonable
out-of-pocket expenses incurred in the performance of its duties as such.

12.   Instructions and Indemnification. The Agent undertakes the duties and
obligations imposed by this Agreement upon the following terms and conditions:

      (a) The Agent shall be entitled to rely upon any instructions or
directions furnished to it by an appropriate officer of the Fund, whether in
conformity with the provisions of this Agreement or constituting a modification
hereof or a supplement hereto. Without limiting the generality of the foregoing
or any other provision of this Agreement, the Agent, in connection with its
duties hereunder, shall not be under any duty or obligation to inquire into the
validity or invalidity or authority or lack thereof of any instruction or
direction from an officer of the Fund which conforms to the applicable
requirements of this Agreement and which the Agent reasonably believes to be
genuine and shall not be liable for any delays, errors or loss of data occurring
by reason of circumstances beyond the Agent's control.

      (b) The Fund will indemnify the Agent and its nominees against, and hold
it harmless from, all liability and expense which may arise out of or in
connection with the services described in this Agreement or the instructions or


<PAGE>

directions furnished to the Agent relating to this Agreement by an appropriate
officer of the Fund, except for any liability or expense which shall arise out
of the failure to perform its duties under this Agreement or the negligence, bad
faith, willful misconduct, of the Agent or such nominees.

13.   Changes in Subscription Certificate. The Agent may, without the consent or
concurrence of the Shareholders in whose names Subscription Certificates are
registered, by supplemental agreement or otherwise, concur with the Fund in
making any changes or corrections in a Subscription Certificate that it shall
have been advised by counsel (who may be counsel for the Fund) is appropriate to
cure any ambiguity or to correct any defective or inconsistent provision or
clerical omission or mistake or manifest error therein or herein contained, and
which shall not be inconsistent with the provision of the Subscription
Certificate except insofar as any such change may confer additional rights upon
the Shareholders.

14.   Assignment, Delegation.

      (a) Except as provided in Section 14(c) below, neither this Agreement nor
any rights or obligations hereunder may be assigned or delegated by either party
without the written consent of the other party.

      (b) This Agreement shall inure to the benefit of and be binding upon the
parties and their respective permitted successors and assigns. Nothing in this
Agreement is intended or shall be construed to confer upon any other person any
right, remedy or claim or to impose upon any other person any duty, liability or
obligation.

      (c) The Agent may, without further consent on the part of the Fund, (i)
subcontract for the performance hereof with Boston EquiServe Limited Partnership
or (ii) subcontract with other subcontractors for systems, processing, and
telephone and mailing services as may be required from time to time; provided,
however, that the Agent shall be as fully responsible to the Fund for the acts
and omissions of any subcontractor as it is for its own acts and omissions.

15.   Governing Law. The validity, interpretation and performance of this
Agreement shall be governed by the law of the Commonwealth of Massachusetts.

16.   Third Party Beneficiaries. This Agreement does not constitute an agreement
for a partnership or joint venture between the Agent and the Fund. Neither party
shall make any commitments with third parties that are binding on the other
party without the other party's prior written consent.

17.   Force Majeure. In the event either party is unable to perform its
obligations under the terms of this Agreement because of acts of God, strikes,
equipment or transmission failure or damage reasonably beyond its control, or
other cause reasonably beyond its control, such party shall not be liable for
damages to the other for any damages resulting from such failure to perform or
otherwise from such causes. Performance under this Agreement shall resume when
the affected party or parties are able to perform substantially that party's
duties.

18.   Consequential Damages. Neither party to this Agreement shall be liable to
the other party for any consequential, indirect, special or incidental damages
under any provisions of this Agreement or for any consequential, indirect,
special or incidental damages arising out of any act or failure to act hereunder
even if that party has been advised of or has foreseen the possibility of such
damages.



<PAGE>

19.   Severability. If any provision of this Agreement shall be held invalid,
unlawful, or unenforceable, the validity, legality, and enforceability of the
remaining provisions shall not in any way be affected or impaired.

20.   Counterparts. This Agreement may be executed in one or more counterparts,
each of which shall be deemed an original and all of which together shall be
considered one and the same agreement.

21.   Captions. The captions and descriptive headings herein are for the
convenience of the parties only. They do not in any way modify, amplify, alter
or give full notice of the provisions hereof.

22.   Facsimile Signatures. Any facsimile signature of any party hereto shall
constitute a legal, valid and binding execution hereof by such party.

23.   Confidentiality. The Agent and the Fund agree that all books, records,
information and data pertaining to the business of the other party which are
exchanged or received pursuant to the negotiation or the carrying out of this
Agreement including the fees for services set forth in the attached schedule
shall remain confidential, and shall not be voluntarily disclosed to any other
person, except as may be required by law.

24.   Term. This Agreement shall remain in effect until terminated on July 30,
1999 (the "Termination Date") or, prior to the Termination Date, upon 30 days'
written notice by either party to the other. Upon termination of the Agreement,
the Exchange Agent shall retain all canceled Certificates and related
documentation as required by applicable law.

25.   Merger of Agreement. This Agreement constitutes the entire agreement
between the parties hereto and supersedes any prior agreement with respect to
the subject matter hereof whether oral or written.

      IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their respective officers, hereunto duly authorized, as of the day
and year first above written.

STATE STREET BANK AND TRUST         INVESCO GLOBAL HEALTH SCIENCES FUND
COMPANY

Charles Rossi                       Ronald L.
- ----------------------------------- -------------------------------
Signature                           Signature


Vice President                      Treasurer
- ----------------------------------- -------------------------------
Title                               Title


May 24, 1999                        May 24, 1999
- ----------------------------------- -------------------------------
Date                                Date






                                  May 24, 1999

Securities and Exchange Commission
450 Fifth Street, N.W.
Judiciary Plaza
Washington, D.C. 20549

Dear Sir or Madam:

         We serve as counsel for the INVESCO  Global  Health  Sciences  Fund,  a
Massachusetts business trust (the "Fund"), in connection with the issuance of up
to 7,539,029  additional  shares of beneficial  interest of the Fund,  par value
$.01  per  share  ("Shares")   pursuant  to  the  Fund's  rights  offering  (the
"Offering") as described in its Registration Statement filed with the Securities
and Exchange  Commission  on Form N-2,  Securities  Act File No.  333-75831  and
Investment  Company Act File No. 811-06476 (the "Registration  Statement").  All
capitalized  terms not otherwise defined herein shall have the meaning set forth
in the Registration Statement.

         As counsel for the Fund, we are familiar with its  Declaration of Trust
and Bylaws, as amended, and we are familiar with the actions taken by the Fund's
board  of  trustees  in  connection  with the  Offering.  We have  examined  its
Registration   Statement,    including   the   prospectus   contained   therein,
substantially  in the form in which it is to become  effective.  We have further
examined and relied upon a certificate of the Secretary of the  Commonwealth  of
Massachusetts to the effect that the Fund is duly established and existing under
the laws of the Commonwealth of  Massachusetts  and is in good standing and duly
authorized to transact business in the Commonwealth of Massachusetts.

         We have also  examined  and relied upon such  corporate  records of the
Fund and other documents and certificates  with respect to factual matters as we
have deemed necessary to render the opinion  expressed  herein. We have assumed,
without  independent  verification,  the  genuineness  of  all  signatures,  the
authenticity of all documents  submitted to us as originals,  and the conformity
with originals of all documents  submitted to us as copies. We also have assumed
that:  at a meeting of the Fund's board of trustees  that is  anticipated  to be
held on or about June 23rd,  1999,  the   Shares  will be duly
authorized; and the Subscription Agent and the Fund, in issuing the Shares, will
act in  compliance  with the  Registration  Statement,  the  Prospectus  and the
Subscription Agent Agreement.

         Based on such examination, we are of the opinion that:

1.             The Fund is duly  organized  and  validly  existing as a business
               trust in good  standing  under  the laws of the  Commonwealth  of
               Massachusetts.


<PAGE>
PaineWebber Incorporated
May 24, 1999
Page 2



2.             The issuance and sale of the Shares pursuant to the Offering have
               been duly  authorized by all necessary  corporate  actions on the
               part of the Fund.

3.             Upon  the  issuance  and  sale  of  the  Shares  pursuant  to the
               Offering,  the  Shares  will be  validly  issued,  fully paid and
               nonassessable.

         We hereby  consent to the filing of this  opinion  in  connection  with
Pre-Effective  Amendment No. 1 to the Company's  Registration  Statement on Form
N-2  (File  No.   333-75831)  being  filed  with  the  Securities  and  Exchange
Commission.  We also  consent to the  reference  to our firm  under the  caption
"Legal Matters" in the Prospectus filed as part of the Registration Statement.


                                   Sincerely,

                                   /s/ KIRKPATRICK & LOCKHART LLP

                                   KIRKPATRICK & LOCKHART LLP



                       CONSENT OF INDEPENDENT ACCOUNTANTS


We hereby  consent to the  incorporation  by  reference  in the  Prospectus  and
Statement of Additional  Information  constituting  parts of this  Pre-Effective
Amendment  No. 1 to the  registration  statement on Form N-2 (the  "Registration
Statement")  of our report  dated  December 8, 1998,  relating to the  financial
statements  and  financial  highlights  appearing in the October 31, 1998 Annual
Report to  Shareholders  of INVESCO Global Health  Sciences Fund,  which is also
incorporated by reference into the  Registration  Statement.  We also consent to
the references to us under the headings "Financial  Highlights" and "Independent
Accountants" in the Prospectus and under the heading  "Financial  Statements" in
the Statement of Additional Information.



PricewaterhouseCoopers LLP
Denver, Colorado
May 19, 1999


                             POWER OF ATTORNEY

         INVESCO  GLOBAL  HEALTH  SCIENCES FUND (the  "Fund"),  a  Massachusetts
business  trust,  and  each  of  its  undersigned   trustees  hereby  nominates,
constitutes,  and  appoints  Glenn A.  Payne,  Ronald  L.  Grooms,  and James F.
Lummanick  with full  power to each of them to act alone as his true and  lawful
attorney-in-fact and agent, for him and on his behalf and in his name, place and
stead in any and all capacities, to make, execute, and sign any and all pre- and
post-effective amendments to the Fund's Form N-2 Registration Statement filed on
April 7, 1999 under the Securities Act of 1933 and the Investment Company Act of
1940,  and to file with the Securities  and Exchange  Commission,  and any other
regulatory  authority having  jurisdiction  over the offer and sale of shares of
beneficial interest of the Fund, any such amendment, and any and all supplements
thereto or to any  prospectus or statement of additional  information  forming a
part  thereof,  and any and all  exhibits,  and  other  documents  requisite  in
connection therewith, granting unto said attorneys, and each of them, full power
and  authority  to do and  perform  each and every act and thing  requisite  and
necessary  to be done in and  about the  premises  as fully to all  intents  and
purposes as the Fund and the undersigned trustees themselves might or could do.

         In addition,  the trustees  hereby  reaffirm  their grant of a power of
attorney  unto Glenn A. Payne  authorizing  him to make,  execute,  and sign the
Registration  Statement  filed on April 7, 1999 with the Securities and Exchange
Commission  on behalf of the  undersigned  trustees and hereby ratify his having
done so in accordance with that power of attorney.

         IN WITNESS WHEREOF, INVESCO GLOBAL HEALTH SCIENCES FUND has caused this
power of attorney to be executed in its name by its  trustees,  and  attested by
its Secretary,  and the  undersigned  trustees have hereunto set their hands and
seals as of the 10th day of May, 1999.

                             INVESCO GLOBAL HEALTH SCIENCES FUND


                             By:  /s/ Charles W. Brady             May 10, 1999
                                  ----------------------------   ---------------
                                   Charles W. Brady, Trustee          DATE



                             By:  /s/ Fred A. Deering              May 10, 1999
                                  ----------------------------   ---------------
                                   Fred A. Deering, Trustee           DATE



                             By:  /s/ John W. McIntyre             May 10, 1999
                                  ----------------------------   ---------------
                                 John W.  McIntyre, Trustee           DATE



                             By:  /s/ Larry Soll                   May 10, 1999
                                  ----------------------------   ---------------
                                   Dr.  Larry Soll, Trustee           DATE
ATTEST:


/s/ Glen A. Payne             May 10, 1999
- --------------------------    ------------
Glen A. Payne, Secretary           DATE



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