INSURED MUNS INCOME TR & INVS QUAL TX EXE TR MULTISERS 164
497J, 1998-05-27
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                              May 27, 1998
                                    
                                    
                                    
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

Attn:  Filing Desk - Stop 1-4
     
     Re:  Insured  Municipals  Income Trust and Investors'  Quality  Tax-
          Exempt Trust, Multi-Series 164
          File No. 33-43688   CIK #881297

Ladies/Gentlemen:
     
     In  accordance  with the provisions of Rule 497(j) of  Regulation  C
under  the  Securities  Act of 1933 (the "Securities  Act")  this  letter
serves to certify that the most recent amendment to the Post-Effective of
the  subject  Registration Statement on Form S-6 for the above  captioned
Trust  does not differ from that which would have been filed pursuant  to
Rule  497(b)  of  the  Securities Act.  Amendment  No.  6  to  the  Post-
Effective,  which was the most recent amendment to the Post-Effective  of
the  Registration Statement, was filed electronically with the Commission
on May 22, 1998.

                                    Very truly yours,
                                    
                                    
                                    
                                    
                                    Van Kampen American Capital
                                      Distributors, Inc.


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