AMYLIN PHARMACEUTICALS INC
SC 13G, 1997-02-13
PHARMACEUTICAL PREPARATIONS
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CUSIP No. 00062936P1                                      Page 1 of 6 Pages


                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C.  20549


                         ________________________


                               SCHEDULE 13G

          Information Statement pursuant to Rules 13d-1 and 13d-2
                 Under the Securities Exchange Act of 1934

                             (Final Amendment)


                NPS Pharmaceuticals, Inc. (Name of Issuer)


                      Common Stock, $.001 par value 
______________________________________________________________________
                      (Title of Class of Securities)



                                00062936P1
______________________________________________________________________
                              (CUSIP Number)













                         ________________________


                                     <PAGE>
CUSIP No. 00062936P1                                      Page 2 of 6 Pages

_________________________________________________________________
1)   Name of Reporting Person                 Biotechnology
     S.S. or I.R.S. Identification            Investments
     No. of Above Person                      Limited
_________________________________________________________________
2)   Check the Appropriate Box                  (a) [   ]
     if a Member of a Group                     (b) [   ]
_________________________________________________________________
3)   SEC Use Only
_________________________________________________________________
4)   Citizenship or Place                     Guernsey,
     of Organization                          Channel Islands
_________________________________________________________________
Number of                5)   Sole Voting    405,938 shares of Shares
                              Beneficially   Power Common Stock, $.001
Owned by Each                                par value ("Common
Reporting Person                             Stock")
                         ________________________________________
                         6)   Shared Voting 
                              Power               -0-
                         ________________________________________
                         7)   Sole Disposi-  405,938 shares of 
                              tive Power     Common Stock
                         ________________________________________
                         8)   Shared Dis-
                              positive Power       -0-
                         ________________________________________

9)   Aggregate Amount Beneficially           405,938 shares of 
     Owned by Each Reporting Person          Common Stock
_________________________________________________________________

10)  Check if the Aggregate
     Amount in Row (9)
     Excludes Certain Shares
_________________________________________________________________
11)  Percent of Class
     Represented by                           3.4%
     Amount in Row (9)
_________________________________________________________________
12)  Type of Reporting 
     Person                                  CO
<PAGE>
CUSIP No. 00062936P1                                      Page 3 of 6 Pages
Final Amendment to Schedule13G
______________________________

          Reference is hereby made to the statement on Schedule 13G
originally filed with the Securities and Exchange Commission on February
14, 1995, as amended by Amendment No. 1 thereto filed on February 9, 1996.

Item 1(a) -    Name of Issuer:  NPS Pharmaceuticals, Inc.

Item 1(b) -    Address of Issuer's Principal Executive Offices:

               420 Chipeta Way            
               Salt Lake City, Utah  84108-1256        
               
Item 2(a) -    Name of Person Filing:

               This statement is being filed on behalf of Biotechnology
               Investments Limited ("BIL" or the "Reporting Person").  BIL
               is a Guernsey, Channel Islands corporation.

Item 2(b) -    Address of Principal Business Office:

               P.O. Box 58
               St. Julian's Court
               St. Peter Port
               Guernsey, Channel Islands  GYI 3BP

Item 2(c) -    Place of Organization:

               Guernsey, Channel Islands

Item 2(d) -    Title of Class of Securities:

               Common Stock, $.001 par value ("Common Stock")

Item 2(e) -    CUSIP Number:  00062936P1 

Item 3 -       Statements Filed Pursuant to Rules 13d-1(b) or 13d-2(b):

               Not applicable.

Item 4 -       Ownership.

          (a)  Amount Beneficially Owned:

               405,938 shares of Common Stock
<PAGE>
CUSIP No. 00062936P1                                      Page 4 of 6 Pages

          (b)  Percent of Class:

               3.4%

          (c)  Number of shares as to which such person has:

               (i)       sole power to vote or to direct the vote:  405,938
                         shares

               (ii)      shared power to vote or to direct the vote:  -0-

               (iii)     sole power to dispose or to direct the disposition
                         of:  405,938 shares

               (iv)      shared power to dispose or to direct the
                         disposition of:  -0-

Item 5 -       Ownership of Five Percent or Less of a Class:

               This statement is being filed to report that as of 
               the date hereof the Reporting Person has ceased to be the
               beneficial owner of more than five percent of the Common
               Stock.

Item 6 -       Ownership of More than Five Percent on Behalf of Another
               Person:

               Not applicable.

Item 7 -       Identification and Classification of the Subsidiary Which
               Acquired the Security Being Reported on By the Parent
               Company:

               Not applicable.

Item 8 -       Identification and Classification of Members of the Group:

               Not applicable.

Item 9 -       Notice of Dissolution of Group:

               Not applicable.

Item 10 -      Certification:

               Not applicable.
<PAGE>
CUSIP No. 00062936P1                                      Page 5 of 6 Pages


Signature:

          After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.

                              BIOTECHNOLOGY INVESTMENTS LIMITED
                              By:  Old Court Limited     
                                                   

                              By  /s/ Kathleen K. Schoemaker
                              _________________________________
                                      Attorney-in-Fact


Date: February 12, 1997
<PAGE>
CUSIP No. 00062936P1                                      Page 6 of 6 Pages

                             OLD COURT LIMITED
         P.O. Box 58, St. Julian's Court, St. Peter Port,
                Guernsey, Channel Islands GYI 3BP

Our Ref:  PF/domain/POA173

12 February 1997

Domain Associates
One Palmer Square
Princeton, New Jersey  08542
USA

Dear Sirs

Biotechnology Investments Limited

We, Old Court Limited hereby authorise you to execute on behalf of Old
Court Limited a Schedule 13G to be filed with the Securities and Exchange
Commission regarding Biotechnology Investments Limited's holdings of NPS
Pharmaceuticals, Inc.

Yours very truly
per pro Old Court Limited

/s/ S.H. Down                           /s/ S.E. Shaw
_________________________               _________________________
S.H. Down, Director                     S.E. Shaw, Director

We confirm that we have authorised Old Court Limited to grant the above
Power of Attorney.

Yours very truly
per pro Biotechnology Investments Limited

/s/ P.A.S. Firth
__________________________________
P.A.S. Firth, Authorised Signatory



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