SELIGMAN HENDERSON GLOBAL FUND SERIES INC
497, 2000-04-05
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    Supplement, dated April 4, 2000, to the Prospectus, dated March 1, 2000,
               of Seligman Global Fund Series, Inc. (the "Series")
                                on behalf of its
                         Seligman Global Technology Fund


     Effective  April  3,  2000,  the  following  supersedes  and  replaces  the
information set forth on pages 23-24 of the Series' Prospectus under the caption
"Global Technology Fund."

Seligman's Global Technology Team manages the Global Technology Fund. The Global
Technology Team is headed by Mr. Paul H. Wick, Vice President of Seligman Global
Fund Series,  Inc. and Co-Portfolio  Manager of the Global Technology Fund since
May 1994.  Mr. Wick has been a Managing  Director of Seligman since January 1995
and a Director of Seligman since November 1997. He joined Seligman in 1987 as an
Associate,  Investment Research.  Mr. Wick has been Vice President and Portfolio
Manager of Seligman Communications and Information Fund, Inc. since January 1990
and  December  1989,  respectively.  He  is  also  Vice  President  of  Seligman
Portfolios,  Inc.  and  Portfolio  Manager of its  Seligman  Communications  and
Information Portfolio and Co-Portfolio Manager of its Seligman Global Technology
Portfolio, and the Seligman New Technologies Fund, Inc.

Mr. Steven A. Werber,  who joined  Seligman on January 10, 2000 as a Senior Vice
President,  is Co-Portfolio  Manager of the Global Technology Fund. He is a Vice
President of Seligman Global Fund Series,  Inc. Prior to joining  Seligman,  Mr.
Werber  was  an  Analyst  and   Portfolio   Manager  at   Fidelity   Investments
International  since 1996.  Prior thereto,  he was an Associate at Goldman Sachs
International from 1992 to 1996. Mr. Werber is also a Vice President of Seligman
Portfolios,  Inc. and  Co-Portfolio  Manager of its Seligman  Global  Technology
Portfolio.


EQSGF1S2-4/00





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