<PAGE> PAGE 1
000 B000000 10/31/99
000 C000000 0000881780
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 3.0
000 J000000 U
001 A000000 DREYFUS GROWTH AND INCOME FUND, INC.
001 B000000 811-6474
001 C000000 2129226775
002 A000000 200 PARK AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10166
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
018 000000 Y
019 A000000 Y
019 B000000 162
019 C000000 DREYFUSFAM
020 A000001 BEAR, STEARNS & CO. INC.
020 B000001 13-3299429
020 C000001 203
020 A000002 ING BARINGS SECURITIES INC.
020 B000002 04-2455153
020 C000002 194
020 A000003 MERRILL LYNCH, PIERCE, FENNER & SMITH INC.
020 B000003 13-5674085
020 C000003 186
020 A000004 DONALDSON, LUFKIN & JENRETTE SECURITIES CORP
020 B000004 13-2741729
020 C000004 168
020 A000005 CIBC OPPENHEIMER
020 B000005 13-5942430
020 C000005 162
020 A000006 AUTRANET, INC.
020 B000006 13-2961507
020 C000006 157
020 A000007 MORGAN STANLEY DEAN WITTER & CO.
020 B000007 13-2655998
020 C000007 153
020 A000008 PAINEWEBBER INCORPORATED
020 B000008 13-2638166
020 C000008 145
020 A000009 SCHRODER, WERTHEIM & CO. INCORPORATED
<PAGE> PAGE 2
020 B000009 13-2697272
020 C000009 141
020 A000010 SANFORD C. BERSTEIN & CO., INC.
020 B000010 13-2625874
020 C000010 130
021 000000 3510
022 A000001 G.X. CLARKE & CO.
022 B000001 13-2969143
022 C000001 718885
022 D000001 1023881
022 A000002 CHASE SECURITIES, INC.
022 B000002 13-3112953
022 C000002 202469
022 D000002 0
022 A000003 DONALDSON, LUFKIN & JENRETTE SECURITIES CORP.
022 B000003 13-2741729
022 C000003 120774
022 D000003 41574
022 A000004 MORGAN STANLEY DEAN WITTER INCORPORATED
022 B000004 13-2655998
022 C000004 23927
022 D000004 61580
022 A000005 PAINEWEBBER INCORPORATED
022 B000005 13-2638166
022 C000005 65237
022 D000005 17561
022 A000006 ROBERT W. BAIRD & CO. INCORPORATED
022 B000006 39-6037917
022 C000006 49467
022 D000006 0
022 A000007 BEAR, STEARNS & CO. INC.
022 B000007 13-3299429
022 C000007 4512
022 D000007 22762
022 A000008 UBS AG
022 B000008 13-2932996
022 C000008 5791
022 D000008 25253
022 A000009 SALOMON SMITH BARNEY,INC.
022 B000009 13-1912900
022 C000009 9643
022 D000009 14826
022 A000010 ABN AMRO SECURITIES (USA) INC.
022 B000010 13-3227945
022 C000010 23349
022 D000010 0
023 C000000 1292844
023 D000000 1247062
024 000000 Y
025 A000001 CHASE SECURITIES, INC.
025 B000001 13-3112953
<PAGE> PAGE 3
025 C000001 E
025 D000001 22019
025 A000002 MORGAN STANLEY DEAN WITTER INCORPORATED
025 B000002 13-2655998
025 C000002 E
025 D000002 18036
025 D000003 0
025 D000004 0
025 D000005 0
025 D000006 0
025 D000007 0
025 D000008 0
028 A010000 59057
028 A020000 0
028 A030000 0
028 A040000 83667
028 B010000 37637
028 B020000 1143
028 B030000 0
028 B040000 93555
028 C010000 56793
028 C020000 0
028 C030000 0
028 C040000 81128
028 D010000 72291
028 D020000 0
028 D030000 0
028 D040000 91754
028 E010000 59724
028 E020000 1278
028 E030000 0
028 E040000 70503
028 F010000 58828
028 F020000 0
028 F030000 0
028 F040000 52257
028 G010000 344330
028 G020000 2421
028 G030000 0
028 G040000 472864
028 H000000 0
062 A000000 N
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
<PAGE> PAGE 4
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 0.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
071 A000000 1496442
071 B000000 1705740
071 C000000 1552083
071 D000000 96
072 A000000 12
072 B000000 3832
072 C000000 22513
072 D000000 0
072 E000000 0
072 F000000 12395
072 G000000 0
072 H000000 0
072 I000000 4239
072 J000000 131
072 K000000 0
072 L000000 79
072 M000000 76
072 N000000 32
072 O000000 1
072 P000000 53
072 Q000000 0
072 R000000 53
072 S000000 23
072 T000000 0
072 U000000 0
072 V000000 0
072 W000000 58
072 X000000 17140
072 Y000000 0
072 Z000000 9205
072AA000000 294311
072BB000000 119438
072CC010000 122581
072CC020000 0
072DD010000 10713
072DD020000 0
072EE000000 102071
073 A010000 0.1230
073 A020000 0.0000
073 B000000 1.1250
073 C000000 0.0000
074 A000000 5148
074 B000000 0
<PAGE> PAGE 5
074 C000000 77311
074 D000000 0
074 E000000 0
074 F000000 1480584
074 G000000 0
074 H000000 0
074 I000000 0
074 J000000 27474
074 K000000 0
074 L000000 2621
074 M000000 63
074 N000000 1593201
074 O000000 10609
074 P000000 1127
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 0
074 R040000 3570
074 S000000 0
074 T000000 1577895
074 U010000 78922
074 U020000 0
074 V010000 19.99
074 V020000 0.00
074 W000000 0.0000
074 X000000 68330
074 Y000000 20237
075 A000000 0
075 B000000 1652714
076 000000 0.00
077 A000000 Y
077 B000000 Y
080 A000000 VIGILANT INSURANCE COMPANY (CHUBB)
080 B000000 NATIONAL UNION FIRE INSURANCE COMPANY (AIG)
080 C000000 125000
081 A000000 Y
081 B000000 180
082 A000000 N
082 B000000 0
083 A000000 N
083 B000000 0
084 A000000 N
084 B000000 0
085 A000000 Y
085 B000000 N
SIGNATURE STEPHANIE PIERCE
TITLE ASSISTANT TREASURER
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000881780
<NAME> DREYFUS GROWTH AND INCOME FUND, INC.
<MULTIPLIER> 1000
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-END> OCT-31-1999
<INVESTMENTS-AT-COST> 1269921
<INVESTMENTS-AT-VALUE> 1557895
<RECEIVABLES> 30095
<ASSETS-OTHER> 5211
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 1593201
<PAYABLE-FOR-SECURITIES> 10609
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 4697
<TOTAL-LIABILITIES> 15306
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 1120354
<SHARES-COMMON-STOCK> 78922
<SHARES-COMMON-PRIOR> 92957
<ACCUMULATED-NII-CURRENT> 413
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 165275
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 291853
<NET-ASSETS> 1577895
<DIVIDEND-INCOME> 22513
<INTEREST-INCOME> 3832
<OTHER-INCOME> 0
<EXPENSES-NET> 17140
<NET-INVESTMENT-INCOME> 9205
<REALIZED-GAINS-CURRENT> 174873
<APPREC-INCREASE-CURRENT> 122581
<NET-CHANGE-FROM-OPS> 306659
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (10713)
<DISTRIBUTIONS-OF-GAINS> (102071)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 37570
<NUMBER-OF-SHARES-REDEEMED> (57679)
<SHARES-REINVESTED> 6074
<NET-CHANGE-IN-ASSETS> (83186)
<ACCUMULATED-NII-PRIOR> 1921
<ACCUMULATED-GAINS-PRIOR> 92473
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 12395
<INTEREST-EXPENSE> 53
<GROSS-EXPENSE> 17140
<AVERAGE-NET-ASSETS> 1652714
<PER-SHARE-NAV-BEGIN> 17.87
<PER-SHARE-NII> .11
<PER-SHARE-GAIN-APPREC> 3.26
<PER-SHARE-DIVIDEND> (.12)
<PER-SHARE-DISTRIBUTIONS> (1.13)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 19.99
<EXPENSE-RATIO> .010
[AVG-DEBT-OUTSTANDING] 1015
[AVG-DEBT-PER-SHARE] .012
</TABLE>
Report of Independent Auditors
To the Shareholders and Board of Directors of
Dreyfus Growth and Income Fund, Inc.
In planning and performing our audit of the financial statements of Dreyfus
Growth and Income Fund, Inc. for the year ended October 31, 1999, we
considered its internal control, including control activities for
safeguarding securities, in order to determine our auditing procedures for
the purpose of expressing our opinion on the financial statements and to
comply with the requirements of Form N-SAR, not to provide assurance on
internal control.
The management of Dreyfus Growth and Income Fund, Inc. is responsible for
establishing and maintaining internal control. In fulfilling this
responsibility, estimates and judgments by management are required to assess
the expected benefits and related costs of controls. Generally, controls that
are relevant to an audit pertain to the entity's objective of preparing
financial statements for external purposes that are fairly presented in
conformity with generally accepted accounting principles. Those controls
include the safeguarding of assets against unauthorized acquisition, use or
disposition.
Because of inherent limitations in internal control, error or fraud may occur
and not be detected. Also, projection of any evaluation of internal control
to future periods is subject to the risk that it may become inadequate
because of changes in conditions or that the effectiveness of the design and
operation may deteriorate.
Our consideration of internal control would not necessarily disclose all
matters in internal control that might be material weaknesses under standards
established by the American Institute of Certified Public Accountants. A
material weakness is a condition in which the design or operation of one or
more of the internal control components does not reduce to a relatively low
level the risk that misstatements caused by error or fraud in amounts that
would be material in relation to the financial statements being audited may
occur and not be detected within a timely period by employees in the normal
course of performing their assigned functions. However, we noted no matters
involving internal control and its operation, including controls for
safeguarding securities, that we consider to be material weaknesses as
defined above at October 31, 1999.
This report is intended solely for the information and use of management, the
Board of Directors of Dreyfus Growth and Income Fund, Inc., and the
Securities and Exchange Commission and is not intended to be and should not
be used by anyone other than these specified parties.
ERNST & YOUNG LLP
December 1, 1999
