DREYFUS GROWTH & INCOME FUND INC /NEW/
N-30D, 2000-12-27
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Dreyfus

Growth and Income

Fund, Inc.

ANNUAL REPORT October 31, 2000

(reg.tm)





The  views  expressed herein are current to the date of this report. These views
and  the  composition  of the fund's portfolio are subject to change at any time
based on market and other conditions.

           * Not FDIC-Insured * Not Bank-Guaranteed * May Lose Value


                                 Contents

                                 THE FUND
--------------------------------------------------

                             2   Letter from the President

                             3   Discussion of Fund Performance

                             6   Fund Performance

                             7   Statement of Investments

                            12   Statement of Securities Sold Short

                            13   Statement of Assets and Liabilities

                            14   Statement of Operations

                            15   Statement of Changes in Net Assets

                            16   Financial Highlights

                            17   Notes to Financial Statements

                            22   Report of Independent Auditors

                            23   Important Tax Information

                                 FOR MORE INFORMATION
---------------------------------------------------------------------------

                                 Back Cover

                                                                       The Fund

                                                                        Dreyfus

                                                   Growth and Income Fund, Inc.

LETTER FROM THE PRESIDENT

Dear Shareholder:

We are pleased to present this annual report for Dreyfus Growth and Income Fund,
Inc.,  covering  the  12-month  period from November 1, 1999 through October 31,
2000.  Inside,  you' ll find valuable information about how the fund was managed
during  the  reporting  period, including a discussion with the fund's portfolio
manager, Douglas D. Ramos, CFA.

The  Standard  & Poor' s  500  Composite  Stock  Price Index, a broad measure of
large-cap  stock  performance,  rose  more  than  6% over the 12-month reporting
period. Investor enthusiasm over technology stocks drove most major stock market
indices  to  new highs. Conversely, in the first nine months of 2000, the equity
investment  environment was marked by dramatic price fluctuations. Additionally,
the  moderating effects of the Federal Reserve Board's (the "Fed") interest-rate
hikes  during  the  first  half  of  2000  helped the Fed to achieve its goal of
slowing  the U.S. economy. Other factors such as higher energy prices and a weak
euro also served to slow economic growth.

Since  stocks  provided  returns well above their historical averages during the
second  half  of  the  1990s,  some  investors  may  have  developed unrealistic
expectations  in  equities. Recent volatility has reminded investors of both the
risks  of  investing  and  the importance of fundamental research and investment
selection.

For  more  information about the economy and financial markets, we encourage you
to visit the Market Commentary section of our website at www.dreyfus.com. Or, to
speak with a Dreyfus customer service representative, call us at 1-800-782-6620

Thank you for investing in Dreyfus Growth and Income Fund, Inc.

Sincerely,


Stephen E. Canter

President and Chief Investment Officer

The Dreyfus Corporation

November 15, 2000




DISCUSSION OF FUND PERFORMANCE

Douglas D. Ramos, CFA, Portfolio Manager

How did Dreyfus Growth and Income Fund, Inc. perform relative to its benchmark?

For  the  12-month  period  ended  October 31, 2000, the fund's total return was
8.10% .(1)  For  the  same period, the total return of the Standard & Poor's 500
Composite  Stock  Price Index ("S&P 500 Index"), the fund's benchmark, was 6.08%
 .(2)

We  believe  that  the  fund  outperformed  the S&P 500 Index largely due to our
effective management of the fund's technology holdings. During the first half of
the  period,  much  of  the  market' s  overall  advance  was driven by gains in
technology-related  stocks.  Although  the  fund held fewer technology stocks on
average  than the S&P 500 Index, our technology holdings produced higher returns
than those of the S&P 500 Index. During the second half of the period, when many
technology  stocks  slumped,  our relatively light exposure to technology stocks
helped us preserve most of the fund's earlier gains.

What is the fund's investment approach?

The  fund  focuses  primarily  on  low- and moderately-priced stocks with market
capitalizations  of  $1  billion  or more at the time of purchase. The fund uses
fundamental  analysis  to  create  a broadly diversified, value-tilted portfolio
typically  exhibiting  a weighted average price-to-earnings ratio less than that
of  the  S&P 500 Index and long-term projected earnings growth greater than that
of  the  S& P  500  Index.  We generally look to avoid the risks associated with
market    timing.

We  typically  measure  a  stock' s  relative  value  by looking at its price in
relation to the company's business prospects and intrinsic worth, as measured by
a  wide  range  of  financial  and  business  data.  By examining each company's
fundamentals,  together with economic and industry trends, we typically look for
factors  that could trigger a rise in the stock's price, such as new competitive
opportunities    or    internal    oper    The    Fund


DISCUSSION OF FUND PERFORMANCE (CONTINUED)

ational  improvements.  The  result  of  our approach was a portfolio containing
stocks from a variety of different market sectors and industries.

What other factors influenced the fund's performance?

The  U.S.  stock  market  experienced  high  levels of volatility throughout the
reporting  period,  largely  due to a sharp rise in technology stocks during the
first  half  and  a  severe decline in the second half. Although many technology
stocks  failed to meet our investment criteria for growth at a reasonable price,
we  identified and invested in several that met our standards, making technology
our  largest single area of investment. Our holdings included semiconductor chip
and  equipment  makers,  such  as  LSI  Logic and Applied Materials; diversified
telecommunications  companies,  such  as  Ericsson  (LM)  Telephone  and  Nortel
Networks;  and  business  and  Internet  software  developers,  such  as Oracle.
Overall,  our  selections performed much better than the technology component of
the  S&P 500 Index during the first half of the period, and were responsible for
virtually all of the fund's gains from November 1999 through mid-March 2000.

During the second half of the period, market strength shifted from technology to
other  industry groups, including financial services, health care and utilities.
We  responded  by  moving  some  of our assets out of technology stocks and into
these  other  areas. These moves limited the impact of the technology decline on
the fund's performance.

In  particular,  we  increased  our  positions in financial services, the fund's
second-largest  group  of  holdings.  Our  financial  stocks  included  mortgage
lenders,  such  as  Federal  National  Home Mortgage Association ("Fannie Mae");
insurers,  such as John Hancock Financial Services; and fee-oriented banks, such
as  the  Bank  of  New  York. These stocks, which suffered in response to rising
interest  rates  during  the  first half of the period, rebounded sharply in the
second half, rising as a group more than 20% from their lows. Our diverse health
care holdings -- including hospital firms, such as HCA Healthcare; HMOs, such as
Wellpoint  Health  Networks;  pharmaceutical  firms,  such  as  Merck & Co.; and
generic    drug    makers,    such   as   ALZA   --   also   performed   well.

And  although  our  utility  holdings represented approximately 5% of the fund's
portfolio,  our  energy-oriented utilities rose even more sharply in response to
climbing    natural    gas    and    petroleum    prices.

On  the  other  hand,  slowing  revenue  growth  hurt  the fund's investments in
consumer  cyclicals  and  communications  services  companies during the period.
Communications  services  holdings,  such  as  AT& T  and  WorldCom,  faced  the
additional burden of rising competition in the long-distance market.

What is the fund's current strategy?

We remain committed to our value-tilted investment approach. From mid-March 2000
through  the  end  of  the  period, value-oriented stocks generally outperformed
growth-oriented  stocks,  the  first time they have done so on a sustained basis
since  late  1997.  While  we can't be sure this trend will continue, we believe
value-oriented  stocks  remain  attractively  priced relative to growth-oriented
stocks. Accordingly, as of October 31, 2000, the fund remains invested in a wide
range  of securities that we believe are attractively valued relative to the S&P
500 Index while offering above-average potential for growth.

November 15, 2000

(1)  TOTAL RETURN INCLUDES REINVESTMENT OF DIVIDENDS AND ANY CAPITAL GAINS PAID.
PAST PERFORMANCE IS NO GUARANTEE OF FUTURE RESULTS. SHARE PRICE AND INVESTMENT
RETURN FLUCTUATE SUCH THAT UPON REDEMPTION, FUND SHARES MAY BE WORTH MORE OR
LESS THAN THEIR ORIGINAL COST.

(2)  SOURCE: LIPPER INC. -- REFLECTS THE REINVESTMENT OF INCOME DIVIDENDS AND,
WHERE APPLICABLE, CAPITAL GAIN DISTRIBUTIONS. THE STANDARD & POOR'S 500
COMPOSITE STOCK PRICE INDEX IS A WIDELY ACCEPTED, UNMANAGED INDEX OF U.S. STOCK
MARKET PERFORMANCE.

<TABLE>
<CAPTION>
                                                             The Fund

FUND PERFORMANCE

Comparison of change in value of $10,000 investment in Dreyfus Growth and Income
Fund, Inc. and the Standard & Poor's 500 Composite Stock Price Index
--------------------------------------------------------------------------------

Average Annual Total Returns AS OF 10/31/00

                                          Inception                                                From

                                            Date             1 Year            5 Years           Inception
------------------------------------------------------------------------------------------------------------------------------------

<S>                                       <C>   <C>            <C>             <C>                <C>
FUND                                      12/31/91             8.10%           13.37%             13.09%

((+))  SOURCE: LIPPER INC.
</TABLE>

PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.

THE ABOVE GRAPH COMPARES A $10,000 INVESTMENT MADE IN DREYFUS GROWTH AND INCOME
FUND, INC. ON 12/31/91 (INCEPTION DATE) TO A $10,000 INVESTMENT MADE IN THE
STANDARD & POOR'S 500 COMPOSITE STOCK PRICE INDEX ON THAT DATE. ALL DIVIDENDS
AND CAPITAL GAIN DISTRIBUTIONS ARE REINVESTED.

THE FUND'S PERFORMANCE SHOWN IN THE LINE GRAPH TAKES INTO ACCOUNT ALL APPLICABLE
FEES AND EXPENSES.  UNLIKE THE FUND, WHICH CAN INVEST IN BOTH EQUITY AND DEBT
SECURITIES, THE STANDARD & POOR'S 500 COMPOSITE STOCK PRICE INDEX IS A WIDELY
ACCEPTED, UNMANAGED INDEX OF U.S. STOCK MARKET PERFORMANCE COMPRISED SOLELY OF
COMMON STOCKS.  THE INDEX DOES NOT TAKE INTO ACCOUNT CHARGES, FEES AND OTHER
EXPENSES.  FURTHER INFORMATION RELATING TO FUND PERFORMANCE, INCLUDING EXPENSE
REIMBURSEMENTS, IF APPLICABLE, IS CONTAINED IN THE FINANCIAL HIGHLIGHTS SECTION
OF THE PROSPECTUS AND ELSEWHERE IN THIS REPORT.
<TABLE>
<CAPTION>




STATEMENT OF INVESTMENTS

October 31, 2000

COMMON STOCKS--99.8%                                                                             Shares                Value ($)
------------------------------------------------------------------------------------------------------------------------------------

COMMERCIAL SERVICES--1.4%

<S>                                                                                              <C>                   <C>
Lamar Advertising                                                                                77,100  (a)           3,700,800

McGraw-Hill Cos.                                                                                261,400               16,778,612

                                                                                                                      20,479,412

CONSUMER NON-DURABLES--6.3%

Anheuser-Busch Cos.                                                                             192,000                8,784,000

Coca-Cola                                                                                       144,000                8,694,000

Flowers Industries                                                                              178,000                2,736,750

Intimate Brands                                                                                 276,000                6,589,500

Kimberly-Clark                                                                                  175,000               11,550,000

PepsiCo                                                                                         386,000               18,696,875

Philip Morris Cos.                                                                              425,000               15,565,625

Procter & Gamble                                                                                158,500               11,322,844

UST                                                                                             382,000                9,645,500

                                                                                                                      93,585,094

CONSUMER SERVICES--5.7%

Adelphia Communications, Cl. A                                                                  184,900  (a)           6,136,369

Cendant                                                                                       1,585,400  (a)          19,024,800

Clear Channel Communications                                                                    173,580  (a)          10,425,649

Disney (Walt)                                                                                   244,900                8,770,481

Infinity Broadcasting, Cl. A                                                                    141,250  (a)           4,696,562

Time Warner                                                                                     189,300               14,369,763

USA Networks                                                                                    347,000  (a)           7,026,750

Viacom, Cl. B                                                                                   259,315  (a)          14,748,541

                                                                                                                      85,198,915

ELECTRONIC TECHNOLOGY--16.3%

American Tower, Cl. A                                                                           305,100  (a)          12,490,031

Amkor Technology                                                                                358,000  (a)           8,055,000

Applied Materials                                                                               111,000  (a)           5,896,875

Cabletron Systems                                                                               346,900  (a)           9,409,663

Compaq Computer                                                                                 572,100               17,397,561

Gateway                                                                                         221,000  (a)          11,405,810

General Dynamics                                                                                100,000                7,156,250

Hewlett-Packard                                                                                 212,000                9,844,750

Intel                                                                                           886,200               39,879,000

International Business Machines                                                                 270,000               26,595,000

KLA-Tencor                                                                                      191,000  (a)           6,458,188

LSI Logic                                                                                       354,000  (a)          11,637,750

                                                                                                     The Fund

STATEMENT OF INVESTMENTS (CONTINUED)

COMMON STOCKS (CONTINUED)                                                                        Shares                Value ($)
------------------------------------------------------------------------------------------------------------------------------------

ELECTRONIC TECHNOLOGY (CONTINUED)

Lucent Technologies                                                                             123,000                2,867,438

Micron Technology                                                                               307,000  (a)          10,668,250

Motorola                                                                                        372,000                9,276,750

National Semiconductor                                                                          168,400  (a)           4,378,400

Nortel Networks                                                                                 241,000               10,965,500

Novellus Systems                                                                                145,900  (a)           5,972,781

Sun Microsystems                                                                                 75,000  (a)           8,315,625

Teradyne                                                                                        209,000  (a)           6,531,250

Texas Instruments                                                                               201,000                9,861,562

United Technologies                                                                              89,000                6,213,312

                                                                                                                     241,276,746

ENERGY MINERALS--6.2%

Anadarko Petroleum                                                                              321,000               20,560,050

Conoco, Cl. A                                                                                   203,000                5,239,938

Exxon Mobil                                                                                     403,831               36,016,677

Royal Dutch Petroleum, ADR                                                                      364,000               21,612,500

Texaco                                                                                          156,500                9,243,281

                                                                                                                      92,672,446

FINANCE--19.1%

American Express                                                                                186,000               11,160,000

American General                                                                                115,300                9,281,650

American International Group                                                                    331,156               32,453,288

Associates First Capital, Cl. A                                                                  81,000                3,007,125

Bank of America                                                                                 207,900                9,992,194

Bank of New York                                                                                230,000               13,239,375

Chase Manhattan                                                                                 150,500                6,847,750

Citigroup                                                                                       840,866               44,250,573

Federal Home Loan Mortgage                                                                      408,200               24,492,000

Federal National Mortgage Association                                                           360,500               27,758,500

FleetBoston Financial                                                                           155,036                5,891,368

Goldman Sachs Group                                                                              49,000                4,890,813

Hartford Financial Services Group                                                                92,000                6,848,250

Household International                                                                         160,800                8,090,250

John Hancock Financial Services                                                                 335,100  (a)          10,597,537

Knight Trading Group                                                                            227,300  (a)           6,804,794

MBNA                                                                                            135,000                5,070,937

Morgan (J.P.)                                                                                    42,000                6,951,000


COMMON STOCKS (CONTINUED)                                                                        Shares                Value ($)
------------------------------------------------------------------------------------------------------------------------------------

FINANCE (CONTINUED)

Morgan Stanley Dean Witter & Co.                                                                262,000               21,041,875

Washington Mutual                                                                               131,000                5,764,000

Wells Fargo                                                                                     398,000               18,432,375

                                                                                                                     282,865,654

HEALTH SERVICES--3.3%

HCA-Healthcare                                                                                  915,200               36,550,800

Wellpoint Health Networks                                                                        98,600  (a)          11,530,038

                                                                                                                      48,080,838

HEALTH TECHNOLOGY--9.7%

ALZA                                                                                             76,000  (a)           6,151,250

Abbott Laboratories                                                                             113,000                5,967,813

American Home Products                                                                          172,700               10,966,450

Baxter International                                                                            110,000                9,040,625

Bristol-Myers Squibb                                                                            221,000               13,467,188

Johnson & Johnson                                                                               104,000                9,581,000

King Pharmaceuticals                                                                            211,000  (a)           9,455,437

Merck & Co.                                                                                     402,000               36,154,875

Pfizer                                                                                          495,750               21,410,203

Pharmacia                                                                                       153,303                8,431,665

Schering-Plough                                                                                 254,000               13,128,625

                                                                                                                     143,755,131

INDUSTRIAL SERVICES--1.4%

Schlumberger                                                                                    189,000               14,387,625

Transocean Sedco Forex                                                                          129,000                6,837,000

                                                                                                                      21,224,625

NON-ENERGY MINERALS--.3%

Alcoa                                                                                           173,000                4,962,937

PROCESS INDUSTRIES--1.9%

Dow Chemical                                                                                    141,000                4,318,125

International Paper                                                                             216,000                7,911,000

Monsanto                                                                                        321,100  (a)           8,185,500

Rohm & Haas                                                                                     259,000                7,786,187

                                                                                                                      28,200,812

PRODUCER MANUFACTURING--6.8%

Emerson Electric                                                                                118,000                8,665,625

General Electric                                                                              1,160,000               63,582,500

Masco                                                                                           330,500                6,176,219

                                                             The Fund

STATEMENT OF INVESTMENTS (CONTINUED)

COMMON STOCKS (CONTINUED)                                                                        Shares                Value ($)
------------------------------------------------------------------------------------------------------------------------------------

PRODUCER MANUFACTURING (CONTINUED)

Tyco International                                                                              387,000               21,938,062

                                                                                                                     100,362,406

RETAIL TRADE--2.8%

Costco Wholesale                                                                                 69,500  (a)           2,545,437

Gap                                                                                             164,000                4,233,250

Lowe's                                                                                          116,600                5,327,163

May Department Stores                                                                           174,350                4,576,688

TJX Cos.                                                                                        490,200               13,357,950

Target                                                                                          412,000               11,381,500

                                                                                                                      41,421,988

TECHNOLOGY SERVICES--7.7%

Avaya                                                                                           295,250  (a)           3,967,422

Charter Communications, Cl. A                                                                   748,700  (a)          14,599,650

Computer Associates International                                                               169,900                5,415,563

Computer Sciences                                                                               205,600  (a)          12,952,800

Electronic Data Systems                                                                         342,300               16,066,706

Microsoft                                                                                       614,000  (a)          42,289,250

Network Associates                                                                              158,600  (a)           3,053,050

Oracle                                                                                          472,000  (a)          15,576,000

                                                                                                                     113,920,441

UTILITIES--10.9%

AT&T                                                                                            164,500                3,814,344

AT&T--Liberty Media Group, Cl. A                                                                344,000  (a)           6,192,000

BellSouth                                                                                       213,000               10,290,563

Coastal                                                                                         371,100               27,994,856

Duke Energy                                                                                     225,000               19,448,438

Dynegy, Cl. A                                                                                   123,200                5,705,700

Enron                                                                                           105,000  (a)           8,616,562

Niagara Mohawk Power                                                                            423,900  (a)           6,782,400

SBC Communications                                                                              466,600               26,916,987

Southern Energy                                                                                  81,100  (a)           2,209,975

TXU                                                                                             210,800                7,812,775

Telefonos de Mexico, Cl. L, ADR                                                                 137,000                7,389,437

Verizon Communications                                                                          416,220               24,062,719

WorldCom                                                                                        213,300  (a)           5,065,875

                                                                                                                     162,302,631

TOTAL COMMON STOCKS

   (cost $1,161,881,814)                                                                                           1,480,310,076


                                                                                               Principal

SHORT-TERM INVESTMENTS--.3%                                                                   Amount ($)               Value ($)
------------------------------------------------------------------------------------------------------------------------------------

U.S. TREASURY BILLS:

   5.94%,12/21/2000                                                                           1,125,000                1,115,089

   6.12%, 1/18/2001                                                                           3,800,000  (b)           3,749,346

TOTAL SHORT-TERM INVESTMENTS

   (cost $4,865,331)                                                                                                   4,864,435
------------------------------------------------------------------------------------------------------------------------------------

TOTAL INVESTMENTS (cost $1,166,747,145)                                                          100.1%            1,485,174,511

LIABILITIES, LESS CASH AND RECEIVABLES                                                            (.1%)              (1,487,154)

NET ASSETS                                                                                       100.0%            1,483,687,357

(A) NON-INCOME PRODUCING.

(B) PARTIALLY HELD BY BROKERS AS COLLATERAL FOR OPEN SHORT POSITIONS.

SEE NOTES TO FINANCIAL STATEMENTS.

                                                             The Fund

STATEMENT OF SECURITIES SOLD SHORT

October 31, 2000

COMMON STOCKS                                                                                   Shares                Value ($)
------------------------------------------------------------------------------------------------------------------------------------

Nortel                                                                                          120,000                5,460,000

Oracle                                                                                          245,000                8,085,000

TOTAL SECURITIES SOLD SHORT (proceeds $13,408,102)                                                                    13,545,000

SEE NOTES TO FINANCIAL STATEMENTS.

</TABLE>

STATEMENT OF ASSETS AND LIABILITIES

October 31, 2000

                                                             Cost         Value
--------------------------------------------------------------------------------

ASSETS ($):

Investments in securities--See Statement of
Investments                                         1,166,747,145  1,485,174,51

Receivable from brokers for proceeds on securities sold short        13,408,102

Receivable for investment securities sold                             3,681,301

Dividends receivable                                                    848,362

Receivable for shares of Common Stock subscribed                        235,851

Receivable for futures variation margin--Note 4(a)                       55,430

Prepaid expenses                                                          9,165

                                                                  1,503,412,722
--------------------------------------------------------------------------------

LIABILITIES ($):

Due to The Dreyfus Corporation and affiliates                         1,194,322

Cash overdraft due to Custodian                                       1,291,635

Securities sold short, at value (proceeds $13,408,102)
  --see Statement of Securities Sold Short                           13,545,000

Payable for investment securities purchased                           2,849,187

Payable for shares of Common Stock redeemed                             560,902

Accrued expenses                                                        284,319

                                                                     19,725,365
--------------------------------------------------------------------------------

NET ASSETS ($)                                                    1,483,687,357
--------------------------------------------------------------------------------

COMPOSITION OF NET ASSETS ($):

Paid-in capital                                                   1,075,882,566

Accumulated undistributed investment income--net                        728,247

Accumulated net realized gain (loss) on investments                  88,786,076

Accumulated net unrealized appreciation (depreciation)
  on investments and securities sold short--Note 4(b)               318,290,468
--------------------------------------------------------------------------------

NET ASSETS ($)                                                    1,483,687,357
--------------------------------------------------------------------------------

SHARES OUTSTANDING

(300 million shares of $.001 par value Common Stock authorized)      76,904,079

NET ASSET VALUE, offering and redemption price per share ($)              19.29

SEE NOTES TO FINANCIAL STATEMENTS.

                                                             The Fund

STATEMENT OF OPERATIONS

Year Ended October 31, 2000

--------------------------------------------------------------------------------

INVESTMENT INCOME ($):

INCOME:

Cash dividends (net of $111,845 foreign taxes withheld at source)   16,412,890

Interest                                                             2,537,024

TOTAL INCOME                                                        18,949,914

EXPENSES:

Management fee--Note 3(a)                                           11,561,659

Shareholder servicing costs--Note 3(b)                               2,799,452

Directors' fees and expenses--Note 3(c)                                113,052

Custodian fees--Note 3(b)                                              102,478

Prospectus and shareholders' reports                                    89,938

Professional fees                                                       68,327

Registration fees                                                       25,256

Miscellaneous                                                           35,219

TOTAL EXPENSES                                                      14,795,381

INVESTMENT INCOME--NET                                               4,154,533
--------------------------------------------------------------------------------

REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS--NOTE 4 ($):

Net realized gain (loss) on investments:

  Long transactions                                                 89,239,083

  Short sale transactions                                             (997,956)

Net realized gain (loss) on financial futures                        5,257,942

NET REALIZED GAIN (LOSS)                                            93,499,069

Net unrealized appreciation (depreciation) on investments
  and securities sold short [including ($3,879,202) net
  unrealized (depreciation) on financial futures]                   26,437,342

NET REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS             119,936,411

NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS               124,090,944

SEE NOTES TO FINANCIAL STATEMENTS.



STATEMENT OF CHANGES IN NET ASSETS

                                                     Year Ended October 31,
                                            ------------------------------------

                                                     2000               1999
--------------------------------------------------------------------------------

OPERATIONS ($):

Investment income--net                          4,154,533           9,205,307

Net realized gain (loss) on investments        93,499,069         174,872,620

Net unrealized appreciation (depreciation)
   on investments                              26,437,342         122,580,859

NET INCREASE (DECREASE) IN NET ASSETS
   RESULTING FROM OPERATIONS                  124,090,944         306,658,786
--------------------------------------------------------------------------------

DIVIDENDS TO SHAREHOLDERS FROM ($):

Investment income--net                        (3,839,868)         (10,712,803)

Net realized gain on investments            (169,987,626)        (102,070,849)

TOTAL DIVIDENDS                             (173,827,494)        (112,783,652)
--------------------------------------------------------------------------------

CAPITAL STOCK TRANSACTIONS ($):

Net proceeds from shares sold                651,194,432          718,800,250

Dividends reinvested                         166,158,765          107,345,114

Cost of shares redeemed                     (861,824,779)      (1,103,206,818)

INCREASE (DECREASE) IN NET ASSETS FROM
   CAPITAL STOCK TRANSACTIONS                (44,471,582)        (277,061,454)

TOTAL INCREASE (DECREASE) IN NET ASSETS      (94,208,132)         (83,186,320)
--------------------------------------------------------------------------------

NET ASSETS ($):

Beginning of Period                         1,577,895,489        1,661,081,809

END OF PERIOD                               1,483,687,357        1,577,895,489

Undistributed investment income--net              728,247              413,582
--------------------------------------------------------------------------------

CAPITAL SHARE TRANSACTIONS (SHARES):

Shares sold                                    34,109,871           37,570,438

Shares issued for dividends reinvested          8,835,349            6,074,347

Shares redeemed                               (44,963,245)         (57,679,437)

NET INCREASE (DECREASE) IN SHARES OUTSTANDING  (2,018,025)         (14,034,652)

SEE NOTES TO FINANCIAL STATEMENTS.

                                                             The Fund
<TABLE>
<CAPTION>

FINANCIAL HIGHLIGHTS

The  following table describes the performance for the fiscal periods indicated.
Total return shows how much your investment in the fund would have increased (or
decreased)  during  each  period,  assuming you had reinvested all dividends and
distributions.  These  figures  have  been  derived  from  the  fund's financial
statements.

                                                                                           Year Ended October 31,
                                                                 -------------------------------------------------------------------

                                                                 2000           1999           1998           1997          1996
------------------------------------------------------------------------------------------------------------------------------------

PER SHARE DATA ($):

<S>                                                             <C>            <C>            <C>            <C>           <C>
Net asset value, beginning of period                            19.99          17.87          19.82          20.53         17.96

Investment Operations:

Investment income--net                                            .05(a)         .11(a)         .18            .34           .35

Net realized and unrealized
   gain (loss) on investments                                    1.51            3.26          1.14           1.97          3.05

Total from Investment Operations                                 1.56            3.37          1.32           2.31          3.40

Distributions:

Dividends from investment income--net                            (.05)          (.12)          (.18)         (.37)          (.32)

Dividends from net realized gain
   on investments                                               (2.21)         (1.13)         (3.09)        (2.65)          (.51)

Total Distributions                                             (2.26)         (1.25)         (3.27)        (3.02)          (.83)

Net asset value, end of period                                  19.29          19.99          17.87         19.82          20.53
------------------------------------------------------------------------------------------------------------------------------------

TOTAL RETURN (%)                                                 8.10          19.79           7.23         12.97          19.41
------------------------------------------------------------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA (%):

Ratio of operating expenses to
   average net assets                                             .96           1.03           1.10          1.01          1.02

Ratio of interest expense and
   dividends on securities sold short
   to average net assets                                           --            .00(b)          --           .01           .01

Ratio of net investment income
   to average net assets                                          .27            .56            .97          1.67          1.78

Portfolio Turnover Rate                                         54.80          96.42         101.87        129.48        131.30
------------------------------------------------------------------------------------------------------------------------------------

Net Assets, end of period ($ x 1,000)                       1,483,687      1,577,895      1,661,082     1,912,408     2,068,453

(A)  BASED ON AVERAGE SHARES OUTSTANDING AT EACH MONTH END.

(B) AMOUNT REPRESENTS LESS THAN .01%.

SEE NOTES TO FINANCIAL STATEMENTS.
</TABLE>


NOTES TO FINANCIAL STATEMENTS

NOTE 1--Significant Accounting Policies:

Dreyfus  Growth  and  Income  Fund,  Inc.  (the  "fund") is registered under the
Investment  Company  Act  of  1940, as amended (the "Act"), as a non-diversified
open-end  management  investment  company. The fund's investment objective is to
provide  investors  with  long-term capital growth, current income and growth of
income, consistent with reasonable investment risk. The Dreyfus Corporation (the
" Manager" ) serves  as  the  fund's investment adviser. The Manager is a direct
subsidiary  of  Mellon Bank, N.A. ("Mellon"), which is a wholly-owned subsidiary
of  Mellon  Financial  Corporation.  Effective  March  22, 2000, Dreyfus Service
Corporation  (the  "Distributor" ), a  wholly-owned  subsidiary  of the Manager,
became  the  distributor  of  the  fund' s  shares, which are sold to the public
without  a  sales charge. Prior to March 22, 2000, Premier Mutual Fund Services,
Inc. was the distributor.

The  fund' s  financial  statements  are  prepared in accordance with accounting
principles generally accepted in the United States, which may require the use of
management  estimates  and  assumptions.  Actual results could differ from those
estimates.

(a)  Portfolio  valuation:  Investments  in  securities  (including  options and
financial futures) are valued at the last sales price on the securities exchange
on  which such securities are primarily traded or at the last sales price on the
national securities market. Securities not listed on an exchange or the national
securities  market,  or  securities  for  which  there were no transactions, are
valued  at  the average of the most recent bid and asked prices, except for open
short positions, where the asked price is used for valuation purposes. Bid price
is used when no asked price is available. Securities for which there are no such
valuations  are  valued  at  fair  value  as  determined in good faith under the
direction  of  the  Board  of  Directors.  Investments  denominated  in  foreign
currencies  are  translated to U.S. dollars at the prevailing rates of exchange.
Forward currency exchange contracts are valued at the forward rate.

(b) Foreign currency transactions: The fund does not isolate that portion of the
results   of   operations   resulting   from   changes   in  foreign   The  Fun

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

exchange  rates  on  investments  from  the fluctuations arising from changes in
market  prices  of  securities held. Such fluctuations are included with the net
realized and unrealized gain or loss from investments.

Net realized foreign exchange gains or losses arise from sales and maturities of
short-term  securities,  sales  of  foreign currencies, currency gains or losses
realized  on  securities  transactions and the difference between the amounts of
dividends,  interest, and foreign withholding taxes recorded on the fund's books
and  the  U.S.  dollar  equivalent of the amounts actually received or paid. Net
unrealized  foreign exchange gains and losses arise from changes in the value of
assets  and  liabilities  other  than  investments in securities, resulting from
changes  in exchange rates. Such gains and losses are included with net realized
and unrealized gain or loss on investments.

(c)  Securities  transactions and investment income: Securities transactions are
recorded  on  a  trade  date  basis.  Realized  gain  and  loss  from securities
transactions  are  recorded  on  the  identified  cost basis. Dividend income is
recognized  on  the  ex-dividend  date  and  interest  income,  including, where
applicable,  amortization  of  discount  on  investments,  is  recognized on the
accrual  basis.  Under the terms of the custody agreement, the fund received net
earnings  credits  of  $11,985 during the period ended October 31, 2000 based on
available cash balances left on deposit. Income earned under this arrangement is
included in interest income.

(d)  Dividends  to shareholders: Dividends are recorded on the ex-dividend date.
Dividends from investment income-net are declared and paid on a quarterly basis.
Dividends  from  net  realized  capital  gain  are  normally  declared  and paid
annually, but the fund may make distributions on a more frequent basis to comply
with  the  distribution  requirements  of  the Internal Revenue Code of 1986, as
amended (the "Code"). To the extent that net realized capital gain can be offset
by  capital  loss  carryovers,  if  any,  it  is  the  policy of the fund not to
distribute such gain.


(e) Federal income taxes: It is the policy of the fund to continue to qualify as
a  regulated  investment company, if such qualification is in the best interests
of  its  shareholders,  by complying with the applicable provisions of the Code,
and  to  make  distributions  of  taxable  income  sufficient to relieve it from
substantially all Federal income and excise taxes.

NOTE 2--Bank Lines of Credit:

The fund may borrow up to $10 million for leveraging purposes under a short-term
unsecured  line of credit and participates with other Dreyfus-managed funds in a
$100  million unsecured line of credit primarily to be utilized for temporary or
emergency  purposes, including the financing of redemptions. Interest is charged
to  the  fund  at rates which are related to the Federal Funds rate in effect at
the  time  of borrowings. During the period ended October 31, 2000, the fund did
not borrow under the line of credit.

NOTE 3--Management Fee and Other Transactions With Affiliates:

(a)  Pursuant  to a management agreement with the Manager, the management fee is
computed  at  the  annual  rate  of .75 of 1% of the value of the fund's average
daily net assets and is payable monthly.

(b) Under the Shareholder Services Plan, the fund reimburses the Distributor, an
amount  not  to  exceed  an  annual rate of .25 of 1% of the value of the fund's
average  daily  net  assets for certain allocated expenses of providing personal
services  and/or  maintaining  shareholder  accounts.  The services provided may
include  personal  services  relating to shareholder accounts, such as answering
shareholder  inquiries  regarding  the  fund  and  providing  reports  and other
information,  and  services  related to the maintenance of shareholder accounts.
During  the  period  ended  October  31,  2000,  the fund was charged $1,588,985
pursuant to the Shareholder Services Plan.

The  fund  compensates  Dreyfus Transfer, Inc., a wholly-owned subsidiary of the
Manager,   under   a   transfer   agency   agreement   for   provid   The   Fun

NOTES TO FINANCIAL STATEMENTS (CONTINUED)

ing  personnel  and facilities to perform transfer agency services for the fund.
During the period ended October 31, 2000, the fund was charged $827,668 pursuant
to the transfer agency agreement.

The  fund  compensates  Mellon under a custody agreement for providing custodial
services  for  the  fund. During the period ended October 31, 2000, the fund was
charged $102,478 pursuant to the custody agreement.

(c)  Each  Board  member also serves as a Board member of other funds within the
Dreyfus  complex  (collectively,  the  "Fund Group"). Effective January 1, 2000,
each  Board  member  who  is  not  an  "affiliated person" as defined in the Act
receives  an  annual  fee  of  $40,000  and an attendance fee of $6,000 for each
meeting attended and $500 for telephone meetings. These fees are allocated among
the  funds  in  the Fund Group. The Chairman of the Board receives an additional
25%  of  such  compensation. Prior to January 1, 2000, each Board member who was
not  an  "affiliated  person"  as  defined  in the Act received from the fund an
annual  fee of $4,500 and an attendance fee of $500 per meeting. The Chairman of
the Board received an additional 25% of such compensation. Subject to the fund's
Emeritus  Program Guidelines, Emeritus Board Members, if any, receive 50% of the
fund's annual retainer fee and per meeting fee paid at the time the Board member
achieves emeritus status.

(d)  During the period ended October 31, 2000, the fund incurred total brokerage
commissions  of  $1,733,779  of  which  $73,642  was  paid  to Dreyfus Brokerage
Services, a wholly-owned subsidiary of Mellon Financial Corporation.

NOTE 4--Securities Transactions:

(a)  The  following  summarizes  the  aggregate amount of purchases and sales of
investment   securities   and   securities   sold  short,  excluding  short-term
securities, during the period ended October 31, 2000:

                                      Purchases ($)               Sales ($)
--------------------------------------------------------------------------------

Long transactions                       819,991,032             939,898,938

Short sale transactions                   5,673,323              18,083,469

     TOTAL                              825,664,355             957,982,407


The  fund  is  engaged  in short-selling which obligates the fund to replace the
security  borrowed  by purchasing the security at current market value. The fund
would  incur  a  loss if the price of the security increases between the date of
the  short  sale  and the date on which the fund replaces the borrowed security.
The  fund  would  realize  a  gain if the price of the security declines between
those  dates.  Until  the  fund  replaces  the  borrowed security, the fund will
maintain daily, a segregated account with a broker and custodian, of permissible
liquid assets sufficient to cover its short position.

The  fund may invest in financial futures contracts in order to gain exposure to
or  protect against changes in the market. The fund is exposed to market risk as
a  result  of  changes  in  the  value  of the underlying financial instruments.
Investments in financial futures require the fund to "mark to market" on a daily
basis,  which  reflects  the  change  in the market value of the contract at the
close of each day's trading. Accordingly, variation margin payments are received
or  made  to  reflect  daily  unrealized gains or losses. When the contracts are
closed,  the  fund recognizes a realized gain or loss. These investments require
initial  margin  deposits  with  a  custodian,  which  consist  of  cash or cash
equivalents, up to approximately 10% of the contract amount. The amount of these
deposits  is  determined by the exchange or Board of Trade on which the contract
is traded and is subject to change. At October 31, 2000, there were no financial
futures outstanding.

(b)  At October 31, 2000, accumulated net unrealized appreciation on investments
and  securities  sold  short  was $318,290,468, consisting of $383,282,207 gross
unrealized appreciation and $64,991,739 gross unrealized depreciation.

At October 31, 2000, the cost of investments for Federal income tax purposes was
substantially  the  same  as  the cost for financial reporting purposes (see the
Statement of Investments).

                                                             The Fund

REPORT OF INDEPENDENT AUDITORS

Shareholders and Board of Directors

Dreyfus Growth and Income Fund, Inc.

We  have audited the accompanying statement of assets and liabilities of Dreyfus
Growth  and  Income  Fund,  Inc.,  including  the  statements of investments and
securities  sold  short  as  of  October  31, 2000, and the related statement of
operations  for  the year then ended, the statement of changes in net assets for
each  of  the  two  years in the period then ended, and financial highlights for
each  of  the  years indicated therein. These financial statements and financial
highlights  are  the responsibility of the Fund's management. Our responsibility
is  to express an opinion on these financial statements and financial highlights
based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to  obtain  reasonable  assurance  about  whether  the  financial statements and
financial  highlights  are  free  of  material  misstatement.  An audit includes
examining,  on  a test basis, evidence supporting the amounts and disclosures in
the  financial  statements  and  financial  highlights.  Our procedures included
verification  by  examination  of securities held by the custodian as of October
31,   2000  and  confirmation  of  securities  not  held  by  the  custodian  by
correspondence  with  others.  An  audit  also includes assessing the accounting
principles  used  and  significant  estimates  made  by  management,  as well as
evaluating  the  overall  financial  statement presentation. We believe that our
audits provide a reasonable basis for our opinion.

In  our  opinion,  the financial statements and financial highlights referred to
above  present  fairly,  in  all  material  respects,  the financial position of
Dreyfus  Growth  and  Income  Fund, Inc. at October 31, 2000, the results of its
operations  for  the  year then ended, the changes in its net assets for each of
the two years in the period then ended, and the financial highlights for each of
the indicated years, in conformity with accounting principles generally accepted
in the United States.


New York, New York

December 8, 2000



IMPORTANT TAX INFORMATION (Unaudited)

For  Federal  tax  purposes,  the  fund  hereby designates $1.560 per share as a
long-term  capital gain distribution of the $2.222 per share paid on December 3,
1999.

The  fund  also  designates  35.905%  of  the ordinary dividends paid during the
fiscal  year  ended  October  31, 2000 as qualifying for the corporate dividends
received  deduction.  Shareholders  will receive notification in January 2001 of
the percentage applicable to the preparation of their 2000 income tax returns.

                                                             The Fund

NOTES

                                                           For More Information

                        Dreyfus Growth and Income Fund, Inc.

                        200 Park Avenue

                        New York, NY 10166

                      Manager

                        The Dreyfus Corporation

                        200 Park Avenue

                        New York, NY 10166

                      Custodian

                        Mellon Bank, N.A.

                        One Mellon Bank Center

                        Pittsburgh, PA 15258

                      Transfer Agent &

                      Dividend Disbursing Agent

                        Dreyfus Transfer, Inc.

                        P.O. Box 9671

                        Providence, RI 02940

                      Distributor

                        Dreyfus Service Corporation

                        200 Park Avenue

                        New York, NY 10166

To obtain information:

BY TELEPHONE Call 1-800-645-6561

BY MAIL  Write to:  The Dreyfus Family of Funds 144 Glenn Curtiss Boulevard
Uniondale, NY 11556-0144

BY E-MAIL  Send your request to [email protected]

ON THE INTERNET  Information can be viewed online or downloaded from:

http://www.dreyfus.com

(c) 2000 Dreyfus Service Corporation                                  010AR0010




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