PREFERRED INCOME OPPORTUNITY FUND INC
NSAR-B, 1997-01-29
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SIGNATURE   RICHARD H. ROSE                              
TITLE       ASSISTANT TREASURER 
 


<TABLE> <S> <C>

<ARTICLE>  6
<SERIES>
              <NUMBER> 001
              <NAME> PREFERRED INCOME OPPORTUNITY FUND INC.
       
<S>                                      <C>
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</TABLE>

 
 
REPORT OF INDEPENDENT ACCOUNTANTS 
 
To the Shareholders and Board of Directors 
of Preferred Income Opportunity Fund Incorporated: 
 
	In planning and performing our audit of the financial statements and
 financial highlights of Preferred Income Opportunity Fund Incorporated
 for the year ended November 30, 1996 we considered its internal 
control structure, including procedures for safeguarding securities,
 in order to determine our auditing procedures for the purpose of
 expressing an opinion on the financial statements and financial
 highlights and to comply with the requirements of Form N-SAR, not to
 provide assurance on the internal control structure. 
 
	The management of Preferred Income Opportunity Fund Incorporated is
 responsible for establishing and maintaining an internal control
 structure. In fulfilling this responsibility, estimates and judgments
 by management are required to assess the expected benefits and
 related costs of internal control structure policies and procedures.
  Two of the objectives of an internal control structure are to provide
 management with reasonable, but not absolute, assurance that assets
 are safeguarded against loss from unauthorized use or disposition and
 that transactions are executed in accordance with management's
 authorization and recorded properly to permit preparation of
 financial statements in conformity with generally accepted
 accounting principles. 
 
	Because of inherent limitations in any internal control structure,
 errors or irregularities may occur and not be detected.  Also,
 projection of any evaluation of the structure to future periods is
 subject to the risk that it may become inadequate because of
 changes in conditions or that the effectiveness of the design 
and operations may deteriorate. 
 
	Our consideration of the internal control structure would not
 necessarily disclose all matters in the internal control structure
 that might be material weaknesses under standards established by the
 American Institute of Certified Public Accountants.  A material weakness
 is a condition in which the design or operation of the specific internal
 control structure elements does not reduce to a relatively low level the
 risk that errors or irregularities in amounts that would be material
 in relation to the financial statements and financial highlights being
 audited may occur and not be detected within a timely period by
 employees in the normal course of performing their assigned functions. 
 However, we noted no matters involving the internal control structure,
 including procedures for safeguarding securities, that we consider to
 be material weaknesses, as defined above, as of November 30, 1996. 
 
	This report is intended solely for the information and use of
 management of Preferred Income Opportunity Fund Incorporated and
 the Securities and Exchange Commission. 
 
 
 
 
Boston, Massachusetts						COOPERS & LYBRAND L.L.P. 
January 3, 1997 




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