CORVAS INTERNATIONAL INC
S-3, EX-5.1, 2000-09-29
PHARMACEUTICAL PREPARATIONS
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                                                                     EXHIBIT 5.1

                           [COOLEY GODWARD LETTERHEAD]

September 29, 2000


CORVAS INTERNATIONAL, INC.
3030 Science Park Road
San Diego, CA  92121

Ladies and Gentlemen:

You have requested our opinion with respect to certain matters in connection
with the filing by CORVAS INTERNATIONAL, INC., a Delaware corporation (the
"Company"), of a Registration Statement on Form S-3 (the "Registration
Statement") with the Securities and Exchange Commission, covering an
underwritten public offering of up to 5,750,000 shares of Common Stock (the
"Shares"), including 750,000 shares subject to the Underwriters' over-allotment
option.

In connection with this opinion, we have examined and relied upon the
Registration Statement and related Prospectus, the Company's Certificate of
Incorporation, as amended, and Bylaws, as amended, and the originals or copies
certified to our satisfaction of such records, documents, certificates,
memoranda and other instruments as in our judgment are necessary or appropriate
to enable us to render the opinion expressed below. We have assumed the
genuineness and authenticity of all documents submitted to us as originals, the
conformity to originals of all documents submitted to us as copies thereof and
the due execution and delivery of all documents where due execution and delivery
are a prerequisite to the effectiveness thereof.

On the basis of the foregoing, and in reliance thereon, we are of the opinion
that the Shares, when issued and sold in accordance with the Registration
Statement and related Prospectus, will be validly issued, fully paid and
nonassessable.

We consent to the reference to our firm under the caption "Legal Matters" in the
Prospectus included on the Registration Statement and to the filing of this
opinion as an exhibit to the Registration Statement.

Very truly yours,

COOLEY GODWARD LLP


/s/ Barbara Borden
Barbara L. Borden







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