TARGET THERAPEUTICS INC
DEL AM, 1996-07-19
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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<PAGE>   1
                                July 19, 1996

VIA EDGAR
- ---------

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

     Target Therapeutics, Inc.
     Registration No. 333-8075
     Registration Statement on Form S-3

Ladies and Gentlemen:

     We are writing to you on behalf of our client, Target
Therapeutics, Inc. (the "Registrant"), in connection with the proposed
registration of 143,775 shares of the Registrant's Common Stock under the
Securities Act of 1933, as amended (the "Act") pursuant to the Registration
Statement set forth above. Due to an administrative oversight, we inadvertently
omitted from the Registration Statement the following language pursuant to Rule
473 of the Act:

    "The  Registrant hereby amends this Registration Statement on such date
    or dates as may be necessary to delay its effective date until the
    Registrant shall file a further amendment which specifically states that
    this Registration Statement shall thereafter become effective in accordance
    with Section 8(A) of the Securities Act of 1933, as amended, or until the
    Registration Statement shall become effective on such date as the
    Commission, acting pursuant to said Section 8(A), may determine."

    We hereby would like this language incorporated by reference into the
Registrant's Registration Statement on Form S-3. We will include this language
in the first amendment to the Registration Statement.

    If you have any questions or comments, please feel free to call me at
(415) 233-8408.

                                          Sincerely, 

                                          VENTURE LAW GROUP
                                          A Professional Corporation

                                          /s/ Amy L. Custalow
                                          Amy L. Custalow

cc:  Kathleen Haller (SEC)
     Robert E. McNamara (Target)
     David A. Garcia (VLG)



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