CHEMTRAK INC/DE
8-K, 1997-12-09
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
 
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM 8-K



               Current Report Pursuant to Section 13 or 15(d) of
                      The Securities Exchange Act of 1934



      Date of Report (Date of earliest event reported):  December 2, 1997



                             CHEMTRAK INCORPORATED
             (Exact name of registrant as specified in its charter)



           Delaware                       0-19749                77-0295388
- -------------------------------   ------------------------   ------------------
(State or other jurisdiction of   (Commission File Number)    (I.R.S. Employer
        incorporation)                                       Identification No.)


                              929 E. Arques Avenue
                            Sunnyvale, CA 94086-4520
                    (Address of principal executive offices)

                                (408) 773-8156
             (Registrant's telephone number, including area code)
<PAGE>
 
ITEM 4.   CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT
          ---------------------------------------------

     On December 2, 1997, the Board of Directors voted to change independent
public accountants, dismissing Ernst & Young LLP as the independent accountants
for ChemTrak, Inc. (the "Company") and engaging Coopers & Lybrand LLP.  Notice
of dismissal was delivered to Ernst & Young on December 4, 1997.

     During the Company's two most recent fiscal years and the subsequent
interim period preceding the dismissal of Ernst & Young, (i) there were no
disagreements with Ernst & Young on any matter of accounting principles or
practices, financial statement disclosure, or auditing scope or procedures,
which if not resolved to its satisfaction would have caused it to make reference
in connection with its reports, and (ii) Ernst & Young has not advised the
Company of any reportable events as defined in paragraph (A) through (D) of
Regulation S-K Item 304(a)(1)(v).

     During the Company's two most recent fiscal years and the subsequent
interim period prior to engaging Coopers & Lybrand, the Company has not
consulted Coopers & Lybrand with respect to any of the matters described in
Regulation S-K Item 304(a)(2)(i) or (ii).

ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS
         ---------------------------------

          A.   Exhibits.

               16.1 - Letter of Ernst & Young dated December 8, 1997 regarding
               the disclosure contained in Item 4 of this report on Form 8-K.
<PAGE>
 
                                   SIGNATURES



     Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                         CHEMTRAK INCORPORATED


Dated:    December 5, 1997               By:  /s/ Donald V. Fluken
                                              -----------------------------
                                              Donald V. Fluken
                                              Vice President, Secretary and
                                              Chief Financial Officer

<PAGE>
 
                                                                    EXHIBIT 16.1

                      [LETTERHEAD OF ERNST & YOUNG LLP]

December 8, 1997

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

Ladies and Gentlemen:

We have read Item 4 of Form 8-K dated December 2, 1997 of ChemTrak 
Incorporated and are in agreement with the statements contained in the first 
paragraph on page one therein. We have no basis to agree or disagree with 
other statements of the registrant contained therein.

                                Very truly yours,

                                /s/ Ernst & Young LLP
                                ---------------------------
                                Ernst & Young LLP


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