PARACELSIAN INC /DE/
SC 13D, 1998-01-26
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D
                    Under the Securities Exchange Act of 1934


                                Paracelsian, Inc.
                                (Name of Issuer)

                               CUSIP No. 698898103

                           Biomar International, Inc.
                                 Nelson Campbell
                                100 Europa Drive
                                    Suite 599
                        Chapel Hill, North Carolina 27514
                           Telephone No. 919-933-2021
           (Name, address and telephone number of person authorized to
                       receive notices and communications)

                                    Copy to:
                                Ronald D. Raxter
                      The Sanford Holshouser Law Firm PLLC
                             234 Fayetteville Street
                                    Suite 100
                          Raleigh, North Carolina 27601

                                January 14, 1998
             (Date of event which requires filing of this statement)


              If the filing person has previously filed a statement
             on Schedule 13G to report the acquisition which is the
                subject of this Schedule 13D, and is filing this
                schedule because of Rule 13D, and is filing this
                  schedule because of Rule 13d-1(b)(3) or (4),
                          check the following box [ ].

                           Check the following box if
                               a fee is being paid
                            with this statement [ ].



<PAGE>


- - ---------------------                                        -------------------

CUSIP NO. 698898103                                                  PAGE 2 OF 6
- - ---------------------                                        -------------------

(1)      NAME OF REPORTING PERSONS.
         S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

         Biomar International, Inc.

(2)      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*             (a) [X]
                                                                       (b) [ ]
         -----------------------------------------------------------------------

(3)      SEC USE ONLY
         -----------------------------------------------------------------------

(4)      SOURCE OF FUNDS*                   BK
         -----------------------------------------------------------------------

(5)      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEM 2(d) or 2(e)                                     [ ]
         -----------------------------------------------------------------------

(6)      CITIZENSHIP OF PLACE OF ORGANIZATION
         Delaware
         -----------------------------------------------------------------------

                  NUMBER OF         (7)              SOLE VOTING POWER
                                                          3,571,429
                  SHARES            --------------------------------------------

                  BENEFICIALLY      (8)              SHARED VOTING POWER
                                                          4,113,764
                  OWNED BY          --------------------------------------------

                  EACH              (9)              SOLE DISPOSITIVE POWER
                                                          3,571,429
                  REPORTING         --------------------------------------------

                  PERSON WITH       (10)             SHARED DISPOSITIVE POWER
                                                          4,113,764
                                    --------------------------------------------


<PAGE>

- - ---------------------                                        -------------------

CUSIP NO. 698898103                                                  PAGE 3 OF 6
- - ---------------------                                        -------------------


(11)              AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
                  PERSON
                                                  4,113,764
                  --------------------------------------------------------------

(12)              CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
                  [ ] CERTAIN SHARES*

                  --------------------------------------------------------------

(13)              PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                  --------------------------------------------------------------

(14)              TYPE OF REPORTING PERSON*
                                    CO
                  --------------------------------------------------------------


(1)      NAME OF REPORTING PERSONS.
         S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

         T. Nelson Campbell

(2)      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*             (a) [X]
                                                                       (b) [ ]
         -----------------------------------------------------------------------

(3)      SEC USE ONLY
         -----------------------------------------------------------------------

(4)      SOURCE OF FUNDS*           BK
         -----------------------------------------------------------------------

(5)      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEM 2(d) or 2(e)                                     [ ]

         -----------------------------------------------------------------------


<PAGE>


- - ---------------------                                        -------------------

CUSIP NO. 698898103                                                  PAGE 4 OF 6
- - ---------------------                                        -------------------

(6)      CITIZENSHIP OF PLACE OF ORGANIZATION
         United States
         -----------------------------------------------------------------------

                  NUMBER OF         (7)              SOLE VOTING POWER
                                                              284,750
                  SHARES            --------------------------------------------

                  BENEFICIALLY      (8)              SHARED VOTING POWER
                                                            3,571,429
                  OWNED BY          --------------------------------------------

                  EACH              (9)              SOLE DISPOSITIVE POWER
                                                              284,750
                  REPORTING         --------------------------------------------

                  PERSON WITH       (10)             SHARED DISPOSITIVE POWER
                                                            3,571,429
                                    --------------------------------------------

(11)              AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
                  PERSON
                                                            3,856,179
                  --------------------------------------------------------------

(12)              CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
                  [ ] CERTAIN SHARES*

                  --------------------------------------------------------------

(13)              PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                  --------------------------------------------------------------

(14)              TYPE OF REPORTING PERSON*
                           IN
                  --------------------------------------------------------------


<PAGE>


- - -------------------                                          -------------------

CUSIP NO. 698898103                                                  PAGE 5 OF 6
- - -------------------                                          -------------------


(1)      NAME OF REPORTING PERSONS.
         S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

         T. Colin Campbell
         -----------------------------------------------------------------------

(2)      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*             (a)  [X]
                                                                       (b)  [ ]
         -----------------------------------------------------------------------

(3)      SEC USE ONLY
         -----------------------------------------------------------------------

(4)      SOURCE OF FUNDS*           BK
         -----------------------------------------------------------------------

(5)      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEM 2(d) or 2(e)                                      [ ]
         -----------------------------------------------------------------------

(6)      CITIZENSHIP OF PLACE OF ORGANIZATION
         United States
         -----------------------------------------------------------------------

                  NUMBER OF         (7)              SOLE VOTING POWER
                                                                111,667
                  SHARES            --------------------------------------------

                  BENEFICIALLY      (8)              SHARED VOTING POWER
                                                              3,717,347
                  OWNED BY          --------------------------------------------

                  EACH              (9)              SOLE DISPOSITIVE POWER
                                                                111,667
                  REPORTING         --------------------------------------------

                  PERSON WITH       (10)             SHARED DISPOSITIVE POWER
                                                              3,717,347
                                    --------------------------------------------


<PAGE>



- - -------------------                                          -------------------

CUSIP NO. 698898103                                                  PAGE 6 OF 6
- - -------------------                                          -------------------

(11)              AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
                  PERSON
                                                         3,829,014
                  --------------------------------------------------------------

(12)              CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
                  [ ] CERTAIN SHARES*

                  --------------------------------------------------------------

(13)              PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                  --------------------------------------------------------------

(14)              TYPE OF REPORTING PERSON*
                           IN
                  --------------------------------------------------------------



<PAGE>



Item 1.  Security and Issuer

         The reporting  persons  acquired the Common Stock of Paracelsian,  Inc.
("Paracelsian"),  par value $0.01 per share.  Principal address is: 222 Langmuir
Laboratories, Cornell Technology Park, Ithaca, New York 14850.

Item 2.  Identity and Background

         The reporting persons are Biomar  International,  Inc. ("Biomar"),  100
Europa Drive, Suite 599, Chapel Hill, North Carolina 27514 and its two principal
shareholders:

         T.  Colin  Campbell  -  Professor  of  Nutritional  Sciences,   Cornell
University, Ithaca, NY
26 Beckett Way
Ithaca, New York 14850

         T. Nelson  Campbell - Chairman and  Executive  Vice  President,  Biomar
International, Inc.,
Chapel Hill, North Carolina
100 Europa Drive, Suite 599
Chapel Hill, North Carolina 27514

(d)      None.

(e)      None.

(f)      United States.

Item 3.  Source and Amount of Funds or Other Consideration

         The source of the $500,000  consideration used by Biomar to acquire the
common stock of Paracelsian  was a line of credit made in the ordinary course of
business by a financial institution.

Item 4.  Purpose of Transaction

         The  purpose of the  transaction  is for  Biomar to acquire  control of
Paracelsian in an attempt to restore shareholder value. Under the Stock Purchase
Agreement,  Biomar  also  received  warrants  to  purchase  up to an  additional
$520,000 in common stock,  in increments  of at least  $100,000,  at a per share
price equal to $0.175.  The Purchase Agreement also provided for the resignation
of the Board of  Directors  serving on January 14, 1998 and the  appointment  of
Biomar's  nominees to the Board of Directors of the  Corporation  (the "Board").
Effective on January 14, 1998, all of the Board members other than the Chairman,
Mr.  Theodore P.  Nikolis,  resigned  immediately  and T. Nelson  Campbell,  the
chairman of the board of directors of Biomar,  was appointed to the Board.  Upon
satisfaction  of the  requirements  of the  SEC  rules  for the  appointment  of
Biomar's nominees, Mr. Nikolis will also resign as a director of the


<PAGE>


Corporation.

Item 5. Interest in Securities of the Issuer

         See responses (7) through (11) on the cover page.

Item 6. Contracts, Arrangements, Understandings or Relationships With Respect to
Securities of the Issuer

         Thomas D.  Livingston,  an officer of Biomar,  will be granted  200,000
shares of the Common Stock and Thomas H. Evans,  an employee of Biomar,  will be
granted  50,000  shares of the Common Stock.  Sylvestor  Johnson IV will also be
granted 2,997 shares of the Common Stock.

Item 7. Material to be Filed as Exhibits

        Stock Purchase Agreement dated January 14, 1998.



<PAGE>



                                    SIGNATURE

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.

Dated:   January 26, 1998                   /s/ T. NELSON CAMPBELL
                                            ----------------------
                                                T. Nelson Campbell

                                            /s/ T. COLIN CAMPBELL
                                            ----------------------
                                                T. Colin Campbell

                                            Biomar International, Inc

                                            BY:  /s/ T. NELSON CAMPBELL
                                            ---------------------------
                                                     T. Nelson Campbell
                                                     Chairman of the Board


<PAGE>



                                  EXHIBIT INDEX

Exhibit 1         Stock Purchase Agreement dated January 14, 1998.




                            STOCK PURCHASE AGREEMENT


         This Agreement  ("Agreement") is entered into this 14th day of January,
1998, by and between Biomar International, Inc., a Delaware corporation with its
principal   offices  in  Chapel  Hill,  North  Carolina  (the  "Purchaser")  and
Paracelsian, Inc., a Delaware corporation with its principal offices in New York
(the "Corporation").

         WHEREAS,  the  Purchaser  desires  to  purchase  from  the  Corporation
3,571,429  newly  issued  shares of the  common  stock of the  Corporation  (the
"Shares") on the terms and subject to the conditions set forth herein; and

         WHEREAS,  the  Board  of  Directors  of  the  Corporation,  due  to the
financial  condition of the  Corporation,  desires to sell to the  Purchaser the
Shares on the terms and subject to the conditions set forth herein.

         NOW THEREFORE, IT IS AGREED AS FOLLOWS:

         SECTION 1. PURCHASE OF SHARES.

         1.1 PURCHASE OF SHARES.  Subject to the terms and  conditions set forth
herein, on or before January 15, 1998 (the "Purchase Date"),  the Purchaser will
purchase 3,571,429 Shares and the Corporation will issue the Shares purchased by
the Purchaser,  said Shares constituting  approximately  thirty percent (30%) of
all of the then issued and  outstanding  capital stock of the  Corporation as of
the Purchase  Date. On the Closing Date (as  hereinafter  defined) the Purchaser
will also receive  warrants to purchase up to an  additional  $520,000 in common
stock, in increments of at least $100,000,  at a per share price equal to $0.175
(the "Warrants"). The Warrants are in the form attached as Exhibit 1.1A and will
be  exercisable at any time prior to their  expiration  which will occur 90 days
from the date the Shares and Warrants are  registered  with the  Securities  and
Exchange  Commission ("SEC") as provided under the Registration Rights Agreement
in the form  attached as Exhibit  1.1B.  To the extent that the  exercise of the
Warrants  will  require an  increase  in the number of  authorized  shares,  the
Corporation  will use its best  efforts  to obtain  shareholder  approval  of an
increase in the  authorized  shares  sufficient to  accommodate  issuance of the
shares under the Warrant.

         1.2 PURCHASE  PRICE.  The Purchaser will pay to the Corporation the sum
of five hundred thousand  dollars  ($500,000) for the Shares (referred herein to
as the "Purchase Price").

         1.3  PAYMENT OF  PURCHASE  PRICE.  The  Purchase  Price will be paid as
follows: (i) the Purchaser will pay to the Corporation the sum of fifty thousand
dollars  ($50,000) on the Closing Date;  and (ii) the Purchaser will deliver the
sum of four hundred and fifty thousand dollars ($450,000) on the Purchase Date.



<PAGE>


         SECTION 2. REPRESENTATIONS AND WARRANTIES OF CORPORATION. As a material
inducement  to the  Purchaser  to enter into this  Agreement  and  purchase  the
Shares,  the  Corporation  represents  and  warrants  that  to the  best  of the
knowledge of the Corporation:

         2.1  ORGANIZATION AND CORPORATE POWER. The Corporation is a corporation
duly  incorporated  and validly existing under the laws of the State of Delaware
and the  Corporation is qualified to do business in every  jurisdiction in which
its ownership of property or conduct of business requires it to qualify,  except
where any failure does not have a material  adverse  effect on the  Corporation.
The Corporation has all requisite corporate power and authority and all material
licenses,   permits,  and  authorizations  necessary  to  own  and  operate  its
properties  and to carry on its  business  as now  conducted,  except  where any
failure does not have a material adverse effect on the  Corporation.  The copies
of the Corporation's articles of incorporation and bylaws have been furnished to
the Purchaser and such copies  reflect all  amendments  made thereto at any time
prior to the date of this Agreement and such copies are correct and complete.

         2.2 CAPITAL STOCK AND RELATED MATTERS. (a) The authorized capital stock
of the  Corporation  consists  of twenty  million  (20,000,000)  Shares,  twelve
million, four thousand,  eight hundred and sixty seven (12,004,867) of which are
issued and outstanding  and are owned,  of record,  as shown on the books of the
Corporation  on December 31, 1997 and no other shares,  common or otherwise,  of
the  Corporation are issued and  outstanding.  Except as listed on Schedule 2.2,
the  Corporation  does not have  outstanding  and has not  agreed,  orally or in
writing,  to issue any shares or securities  convertible or exchangeable for any
shares, nor does it have outstanding nor has it agreed, orally or in writing, to
issue any  options or rights to purchase or  otherwise  acquire its shares.  The
Corporation  is not  subject to any  obligation  (contingent  or  otherwise)  to
repurchase or otherwise acquire or retire any of its shares. Except as listed on
Schedule 2.2, the Corporation has not violated any applicable securities laws or
regulations in connection  with the offer or sale of its  securities  other than
violations  that have been,  or will before the Closing have been,  corrected by
post-issuance  filings.  All  of the  outstanding  shares  of the  Corporation's
capital stock are validly issued,  fully paid, and nonassessable.  Upon purchase
thereof  pursuant to the terms of this Agreement,  the Purchaser will have, good
and marketable  title to the Shares,  free and clear of all security  interests,
liens,   encumbrances,   or  other  restrictions  or  claims,  subject  only  to
restrictions as to marketability  imposed by securities laws.  Assuming that the
representations  in Section 3.6 are true and correct,  the  Corporation  has not
violated or will not violate any applicable  securities  laws in connection with
the offer or sale of the Shares to the Purchaser hereunder.  (b) Except as noted
on  Schedule  2.2 or where the  failure  to file would not have had or could not
have a material and adverse effect on the Corporation, the Corporation has filed
all reports, registrations and statements, together with any amendments required
to be made with respect thereto,  that were required to be filed with the SEC or
any other governmental or regulatory  authorities  having  jurisdiction over the
Corporation.  All  such  reports,  registrations  and  statements  filed  by the
Corporation  with the SEC or other such  regulatory  authority are  collectively
referred to herein as the "Reports." As of their respective  dates,  each Report
complied in all material  respects with all the statutes,  rules and regulations
enforced or promulgated by the regulatory  authority with which it was filed and
did not contain any untrue


                                       -2-

<PAGE>


statement  of a material  fact or omit to state a material  fact  required to be
stated  therein or necessary  to make the  statements  therein,  in light of the
circumstances  under which they were made, not  misleading.  The Corporation has
not been notified that any such Report was deficient in any material  respect as
to form or content.

         2.3  SUBSIDIARIES.  The  Corporation  has no operating  subsidiaries or
affiliated  companies  and  does  not  otherwise  own or  control,  directly  or
indirectly, any equity interest in any operating corporation or entity.

         2.4 CONDUCT OF BUSINESS;  LIABILITIES.  Except as set forth in Schedule
2.4, the Corporation is not in default under,  and no condition exists that with
notice or lapse of time would constitute a default of the Corporation  under (i)
any mortgage,  loan agreement,  evidence of  indebtedness,  or other  instrument
evidencing  borrowed  money to which the  Corporation is a party or by which the
Corporation or the properties of the Corporation are bound or (ii) any judgment,
order, or injunction of any court, arbitrator, or governmental agency that would
reasonably  be  expected  to  affect  materially  and  adversely  the  business,
financial  condition,  or results of  operations of the  Corporation  taken as a
whole.

         2.5  FINANCIAL  STATEMENTS.  (a) The audited  balance  sheet and income
statement of the Corporation as of the 30th day of September,  1997, in the form
attached to this  Agreement as Exhibit  2.5(A) and the income  statement for the
period  ending the 30th day of  September,  1997,  in the form  attached to this
Agreement as Exhibit 2.5(B)  (collectively the "Audited Financial  Statements"),
fairly  presents  in  all  material  respects  the  financial  position  of  the
Corporation  as of the 30th day of  September,  1997  and has been  prepared  in
accordance with generally accepted accounting principles,  consistently applied,
and in a manner substantially  consistent with prior financial statements of the
Corporation.  The latest  unaudited,  balance sheet and income  statement of the
Corporation  as of the 31st day of December,  1997 and for the month then ended,
in the form attached hereto as Exhibit 2.5(C) ("Latest  Financial  Statements"),
fairly  presents  in  all  material  respects  the  financial  position  of  the
Corporation  as of the 31st day of December,  1997 and the results of operations
for the one month then ended and have been prepared in accordance with generally
accepted   accounting   principles   consistently   applied   and  in  a  manner
substantially  consistent  with the  Audited  Financial  Statements,  except for
differences resulting from normally occurring audit adjustments,  including, but
not  limited  to,  income tax and tax  accrual  adjustments,  or as noted in the
Latest Financial  Statements or the notes thereto.  Except as contemplated by or
permitted under this Agreement,  there are no adjustments that would be required
on review of the Latest Financial Statements that would,  individually or in the
aggregate,  have a material  negative  effect  upon the  Corporation's  reported
financial condition.  (b) The audited balance sheet of the Corporation as of the
30th day of September, 1997, reflects a tangible book value of not less than two
million two hundred  thousand  dollars  ($2,200,000).  The  unaudited  financial
statements  of the  Corporation  as of November 30, 1997,  reflect not less than
$500,000  in cash and cash  equivalents  and no more than  $275,000  in payables
(excluding  any  contingent  liabilities  arising out of any lawsuits which have
been


                                       -3-

<PAGE>



disclosed in the filings made with the SEC),  obligations and other liabilities.
Monthly,  recurring  operational  expenses  of the  Corporation  do  not  exceed
$75,000.

         2.6  NO  UNDISCLOSED  LIABILITIES.   Except  for  (i)  liabilities  and
obligations  incurred in the ordinary  course of business  since the 31st day of
December, 1997 ("Statement Date"), and (ii) liabilities or obligations described
in  Schedule  2.6,  neither  the  Corporation  nor  any of the  property  of the
Corporation is subject to any material liability or obligation that was required
to be included or adequately reserved against in the Latest Financial Statements
or described in the notes thereto and was not so included,  reserved against, or
described.

         2.7 ABSENCE OF CERTAIN CHANGES.  Except as contemplated or permitted by
this  Agreement or as described in Schedule 2.7,  since the Statement Date there
has not been:

         2.7.1 Any material adverse change in the business, financial condition,
operations, or assets of the Corporation;

         2.7.2 Any damage, destruction, or loss, whether covered by insurance or
not   materially   adversely   affecting  the  properties  or  business  of  the
Corporation;

         2.7.3  Any sale or  transfer  by the  Corporation  of any  tangible  or
intangible asset other than in the ordinary course of business,  any mortgage or
pledge or the creation of any security  interest,  lien, or  encumbrance  on any
such asset, or any lease of property,  including equipment, other than tax liens
with respect to taxes not yet due and contract rights of customers in inventory;

         2.7.4 Any  declaration,  setting aside, or payment of a distribution in
respect of or the redemption or other repurchase by the Corporation of any stock
of the Corporation;

         2.7.5 Any material  transaction  not in the ordinary course of business
of the Corporation;

         2.7.6 The lapse of any material  trademark,  assumed name,  trade name,
service  mark,  copyright,  or license or any  application  with  respect to the
foregoing;

         2.7.7 The grant of any  increase  in the  compensation  of  officers or
employees  (including  any  such  increase  pursuant  to  any  bonus,   pension,
profit-sharing,  or other plan)  other than  customary  increases  on a periodic
basis or  required by  agreement  or  understanding  in the  ordinary  course of
business and in accordance with past practice;

         2.7.8 The discharge or satisfaction of any material lien or encumbrance
or the payment of any material  liability other than current  liabilities in the
ordinary course of business;

         2.7.9 The making of any material loan,  advance,  or guaranty to or for
the benefit of any person  except the  creation of  accounts  receivable  in the
ordinary course of business; or


                                       -4-

<PAGE>



         2.7.10  An agreement to do any of the foregoing.

         2.8 TITLE AND RELATED MATTERS. Except as set forth in Schedule 2.8, the
Corporation  has good and  marketable  title  to all of its  property,  real and
personal,  and other assets included in the Latest Financial  Statements (except
properties and assets sold or otherwise  disposed of subsequent to the Statement
Date in the ordinary course of business or as  contemplated in this  Agreement),
free and clear of all security interests,  mortgages,  liens, pledges,  charges,
claims, or encumbrances of any kind or character, except (i) statutory liens for
property  taxes not yet  delinquent  or payable  subsequent  to the date of this
Agreement and statutory or common law liens  securing the payment or performance
of any obligation of the Corporation, the payment or performance of which is not
delinquent,  or that is payable  without  interest or penalty  subsequent to the
date on which this  representation  is given,  or the validity of which is being
contested in good faith by the Corporation;  (ii) the rights of customers of the
Corporation with respect to inventory under orders or contracts  entered into by
the  Corporation in the ordinary  course of business;  (iii) claims,  easements,
liens, and other  encumbrances of record pursuant to filings under real property
recording  statutes;  and (iv) as described in the  Unaudited  Statements or the
notes thereto.

         2.9  LITIGATION.  Except as set  forth in  Schedule  2.9,  there are no
material actions, suits, proceedings, orders, investigations,  or claims pending
or, to the best of the Corporation's  knowledge,  overtly threatened against the
Corporation  or any of its  property,  at law or in equity,  or before or by any
governmental department,  commission, board, bureau, agency, or instrumentality;
the Corporation is not subject to any arbitration  proceedings  under collective
bargaining  agreements  or  otherwise  or,  to the  best  of  the  Corporation's
knowledge, any governmental investigations or inquiries; and the Corporation has
received in writing no threat of any of the foregoing.

         2.10 TAX  MATTERS.  Except  as set  forth  on  Schedule  2.10,  (i) the
Corporation  has prepared in a  substantially  correct  manner and has filed all
federal,  state,  local, and foreign tax returns and reports heretofore required
to be filed by them and have paid all taxes  shown as due  thereon;  and (ii) no
taxing  authority  has  asserted  any  deficiency  in the  payment of any tax or
informed the  Corporation  that it intends to assert any such  deficiency  or to
make any audit or other  investigation  of the  Corporation  for the  purpose of
determining   whether  such  a  deficiency   should  be  asserted   against  the
Corporation.

         2.11  COMPLIANCE  WITH LAWS.  Except as listed on  Schedule  2.11,  the
Corporation is, in the conduct of its business,  in substantial  compliance with
all laws,  statutes,  ordinances,  regulations,  orders,  judgments,  or decrees
applicable to them, the  enforcement  of which,  if the  Corporation  was not in
compliance therewith,  would have a materially adverse effect on the business of
the Corporation, taken as a whole. The Corporation has received no notice of any
asserted  present or past failure by the  Corporation  to comply with such laws,
statutes, ordinances, regulations, orders, judgments, or decrees.


                                       -5-

<PAGE>


         2.12  NO  BROKERS  OR  FINDERS.  There  are  no  claims  for  brokerage
commissions,  finders'  fees or  similar  compensation  in  connection  with the
transactions  contemplated  by  this  Agreement  based  on  any  arrangement  or
agreement made by or on behalf of the Corporation.

         2.13 INSURANCE.  Schedule 2.13 contains a list of each insurance policy
maintained  by the  Corporation  with  respect to its  properties,  assets,  and
businesses, and each such policy is in full force and effect. The Corporation is
not in material  default with respect to its  obligations  under any such policy
maintained by it. The Corporation  has not been notified of the  cancellation of
any of the  insurance  policies  listed  on  Schedule  2.13  or of any  material
increase in the premiums to be charged for such insurance policies.

         2.14  EMPLOYEES  AND LABOR  RELATIONS  MATTERS.  Except as set forth in
Schedule 2.14 or as provided in this  Agreement,  no employee or former employee
of the  Corporation  is in  violation  of any  material  term of any  employment
contract,  patent  disclosure  agreement  or any  other  contract  or  agreement
relating to the  relationship of such employee with the Corporation or any other
party because of the nature of the business  conducted or to be conducted by the
Corporation.  Each employee or former employee of the Corporation with access to
confidential or proprietary  information has executed, or in the ordinary course
will execute, a proprietary  information  agreement  obligating such employee to
hold confidential the Corporation's proprietary information. The Corporation has
in all material  respects  complied with all  applicable  state and federal laws
related to employment.

         2.15  DISCLOSURE.  Neither  this  Agreement  nor any of the  schedules,
attachments,  written  statements,  documents,   certificates,  or  other  items
prepared or supplied to the  Purchaser by or on behalf of the  Corporation  with
respect to this purchase contain any untrue statement of a material fact or omit
a material fact necessary to make each statement contained herein or therein not
misleading.  The Corporation has not  intentionally  concealed any fact known to
have a material  adverse  effect  upon the  Corporation's  existing  or expected
financial condition,  operating results,  assets,  customer relations,  employee
relations, or business prospects taken as a whole.

         2.16  POWER OF  ATTORNEY.  No  material  power of  attorney  or similar
authorization given by the Corporation is presently in effect.

         2.17 ACCOUNTS  RECEIVABLE.  All accounts  receivable of the Corporation
reflected in the Latest Financial  Statements represent bona fide sales actually
made in the ordinary course of business.

         2.18 AGREEMENTS AND COMMITMENTS.  Schedule 2.18 contains a complete and
accurate list of each agreement, contract, instrument, and commitment (including
license  agreements)  to which the  Corporation  is a party  that  provides  for
payments  in excess of  $10,000  per year or whose term is in excess of one year
and is not  cancelable  upon 30 or fewer days'  notice  without  any  liability,
penalty,  or premium,  other than a nominal  cancellation  fee or charge ("Third
Party  Agreements").  Except  as  otherwise  set  forth in  Schedule  2.18,  the
Corporation is not in material default under any Third Party Agreements, nor, to
the Corporation's best knowledge, does there


                                       -6-

<PAGE>


exist  any  event  that,  with  notice  or the  passage  of time or both,  would
constitute a material  default or event of default by the Corporation  under any
Third Party Agreements.

         2.19  PERSONAL  PROPERTY.  Without  material  exception,  Schedule 2.19
contains lists of all tangible personal property and assets owned or held by the
Corporation  and  used  or  useful  in  the  conduct  of  the  business  of  the
Corporation.  Except as set forth in Schedule 2.19, the Corporation owns and has
good  title to such  properties  and none of such  properties  is subject to any
security interest,  mortgage, pledge, conditional sales agreement, or other lien
or encumbrance  (except for liens for current taxes,  assessments,  charges,  or
other  governmental  levies  not yet  due  and  payable).  The  Corporation  has
delivered to the Purchaser copies of all leases and other agreements relating to
property  described in Schedule 2.19 (including any and all amendments and other
modifications  to such leases and other  agreements)  all of which are valid and
binding, and the Corporation is not in material default under any such leases or
agreements.  Except  as set  forth  in  Schedule  2.19  and to the  best  of the
Corporation's knowledge, all material properties listed therein are generally in
good  operating  condition and repair  (ordinary  wear and tear  excepted),  are
performing satisfactorily, and are available for immediate use in the conduct of
the business and operations of the Corporation. To the best of the Corporation's
knowledge,  all such tangible personal property is in compliance in all material
respects with all applicable statutes,  ordinances,  rules, and regulations. The
properties  listed in Schedule 2.19 include  substantially  all such  properties
necessary to conduct the  business  and  operations  of the  Corporation  as now
conducted.

         2.20 INTELLECTUAL  PROPERTY.  The Corporation (i) owns or has the right
to use, free and clear of all liens,  charges,  claims and  restrictions,  those
patents, trademarks, service marks, trade names, copyrights, licenses, and other
intellectual  property rights  necessary for the operation of its businesses now
conducted or presently proposed to be conducted,  and (ii) to its knowledge, and
except for the payments  required in connection with those patents,  trademarks,
service marks, trade names, copyrights, licenses and other intellectual property
rights  listed  on  Schedule  2.20,  is not  obligated  or under  any  liability
whatsoever  to make any payments by way of  royalties,  fees or otherwise to any
owner or licensee of, or other claimant to, any patent, trademark, service mark,
trade name, copyright or other intangible asset, with respect to the use thereof
or in connection with the conduct of its business or otherwise. To the knowledge
of the Corporation,  the Corporation has not infringed upon nor is it infringing
upon any  patent,  trademark,  service  mark,  trade  name,  copyright  or other
intellectual  property of any third party.  The  Corporation is not aware of any
violation  by a  third  party  of any of the  Corporation's  patents,  licenses,
trademarks,  service  marks,  trade names,  copyrights,  trade  secrets or other
proprietary rights.

         2.21 ERISA AND RELATED  MATTERS  Schedule 2.21 sets forth a description
of all "Employee Welfare Benefit Plans" and "Employee Pension Benefit Plans" (as
defined in ss.ss. 3(1) and 3(2), respectively, of the Employee Retirement Income
Security Act of 1974, as amended ("ERISA")) existing on the date hereof that are
or have been maintained or contributed to by the  Corporation.  Except as listed
on Schedule 2.21, the  Corporation  does not maintain any retirement or deferred
compensation plan, savings, incentive, stock option or stock purchase


                                       -7-

<PAGE>



plan,  unemployment  compensation  plan,  vacation pay,  severance pay, bonus or
benefit  arrangement,  insurance or hospitalization  program or any other fringe
benefit  arrangement for any employee,  consultant or agent of the  Corporation,
whether  pursuant to contract,  arrangement,  custom or informal  understanding,
which does not constitute an "Employee  Benefit Plan" (as defined in ss. 3(3) of
ERISA),  for which the Corporation may have any ongoing material liability after
Closing.  The Corporation  does not maintain nor has it ever  contributed to any
Multiemployer  Plan as defined by ss. 3(37) of ERISA.  The Corporation  does not
currently  maintain  any  Employee  Pension  Benefit Plan subject to Title IV of
ERISA. There have been no "prohibited  transactions" (as described in ss. 406 of
ERISA or ss. 4975 of the Code) with respect to any Employee Pension Benefit Plan
or Employee  Welfare  Benefit Plan maintained by the Corporation as to which the
Corporation has been a party. As to any employee  pension benefit plan listed on
Schedule  2.21 and subject to Title IV of ERISA,  there have been no  reportable
events (as such term is defined in ss. 4043 of ERISA).

         2.22 OPERATING  RIGHTS.  The Corporation  has all operating  authority,
licenses,  franchises,  permits,  certificates,  consents, rights and privileges
(collectively  "Licenses")  as are necessary or  appropriate to the operation of
its  business as now  conducted  and which the  failure to possess  would have a
material adverse effect on the assets,  operations or financial condition of the
Corporation.  Except where any failure would not have a material  adverse effect
on the  Corporation,  such Licenses are in full force and effect,  no violations
have been or are expected to have been recorded in respect of any such licenses,
and no proceeding is pending or, to the knowledge of the Corporation, threatened
that could result in the  revocation  or limitation  of any such  licenses.  The
Corporation has conducted its business so as to comply in all material  respects
with all such Licenses.

         2.23 TRANSACTIONS  WITH AFFILIATES.  Except for regular salary payments
and  fringe  benefits  under  an  individual's  compensation  package  with  the
Corporation, none of the officers, employees,  directors, or other affiliates of
the  Corporation,  or members of their  families  is a party to any  agreements,
understandings,  or proposed transactions with the Corporation.  The Corporation
has not  guaranteed or assumed any  obligations of the  Corporation's  officers,
directors, or employees.

         2.24 MINUTE  BOOKS.  Except as described on Schedule  2.24,  the minute
books of the Corporation  contain a materially  complete summary of all meetings
of directors and shareholders  since the time of  incorporation  and reflect all
transactions referred to in such minutes accurately in all material respects.

         2.25 KNOWLEDGE. Notwithstanding anything to the contrary herein, to the
extent that any of the representations and warranties  contained in this Section
2 shall have been breached and the fact or facts  constituting  such breach were
at the date hereof known to T. Colin Campbell and T. Nelson  Campbell,  then and
in such event, no breach shall be deemed to have occurred.


                                       -8-

<PAGE>



         SECTION 3.  REPRESENTATIONS AND WARRANTIES OF PURCHASER.  As a material
inducement to the  Corporation to enter into this Agreement and sell the Shares,
the Purchaser hereby represents and warrants to the Corporation that to the best
of the knowledge of the Purchaser:

         3.1   ORGANIZATION;   POWER.   The  Purchaser  is  a  corporation  duly
incorporated  and validly  existing  under the laws of the State of Delaware and
has all requisite corporate power and authority to enter into this Agreement and
perform its obligations hereunder.

         3.2  AUTHORIZATION.  The execution,  delivery,  and  performance by the
Purchaser of this  Agreement  and all other  agreements  contemplated  hereby to
which the  Purchaser  is a party have been duly and  validly  authorized  by all
necessary  corporate  action of the Purchaser,  and this Agreement and each such
other  agreement,  when  executed  and  delivered by the parties  thereto,  will
constitute the legal, valid, and binding obligation of the Purchaser enforceable
against it in accordance with its terms, except as enforceability may be limited
by applicable bankruptcy,  insolvency, and similar statutes affecting creditors'
rights generally and judicial limits on equitable remedies.

         3.3 NO CONFLICT WITH OTHER  INSTRUMENTS OR  AGREEMENTS.  The execution,
delivery,  and  performance  by the  Purchaser of this  Agreement  and all other
agreements contemplated hereby to which the Purchaser is a party will not result
in a breach or  violation  of, or  constitute a default  under,  its Articles of
Incorporation  or Bylaws or any material  agreement to which the  Purchaser is a
party or by which the Purchaser is bound.

         3.4 GOVERNMENTAL AUTHORITIES.  Except as set forth in Schedule 3.4, (i)
the Purchaser is not required to submit any notice, report, or other filing with
any  governmental  or regulatory  authority in connection with the execution and
delivery by the Purchaser of this Agreement and the consummation of the purchase
and  (ii)  no  consent,  approval,  or  authorization  of  any  governmental  or
regulatory  authority  is  required  to be  obtained  by  the  Purchaser  or any
affiliate  in  connection  with  the  Purchaser's   execution,   delivery,   and
performance of this Agreement and the consummation of this purchase.

         3.5  LITIGATION.   There  are  no  actions,  suits,   proceedings,   or
governmental  investigations  or inquiries  pending or, to the  knowledge of the
Purchaser,   threatened  against  the  Purchaser  or  its  properties,   assets,
operations,  or businesses that might delay, prevent, or hinder the consummation
of this purchase.

         3.6 INVESTMENT REPRESENTATIONS

         3.6.1  The  Purchaser  is  a   corporation   in  good  standing  and  a
sophisticated  investor  that  has  substantial  experience  in  evaluating  and
investing in private  placement  transactions of securities in companies similar
to the Corporation so that the Purchaser is capable of evaluating the merits and
risks of the  Purchaser's  investment in the Corporation and has the capacity to
protect the Purchaser's own interests.


                                       -9-

<PAGE>

         3.6.2 The  Purchaser is  acquiring  the Shares for  investment  for the
Purchaser's own account, not as a nominee or agent, and not with the view to, or
for  resale  in  connection  with,  any  distribution   thereof.  The  Purchaser
understands  that the Shares to be purchased have not been registered  under the
Securities Act of 1933 ("Securities Act") or the securities laws of any state by
reason  of  a  specific  exemption  from  the  registration  provisions  of  the
Securities Act and the applicable  state  securities  laws, the  availability of
which depends upon,  among other things,  the bona fide nature of the investment
intent and the accuracy of the Purchaser's  representations as expressed herein.
The Purchaser is acquiring the Shares without  expectation,  desire, or need for
resale  and not with the  view  toward  distribution,  resale,  subdivision,  or
fractionalization of the Shares except as provided under the Registration Rights
Agreement.

         3.6.3 The Purchaser  understands  that the Shares to be purchased  have
not been registered  under Securities Act, or under any state securities law and
will contain a legend to that effect.

         3.6.4 The Purchaser  understands  that the Shares cannot be resold in a
transaction to which the Securities Act and state  securities  laws apply unless
(i)  subsequently  registered  under the  Securities  Act and  applicable  state
securities laws or (ii) exemptions from such  registrations  are available.  The
Purchaser  is  aware  of the  provisions  of  Rule  144  promulgated  under  the
Securities  Act which  permit  limited  resale of shares  purchased in a private
transaction subject to the satisfaction of certain conditions.

         3.7 TAX LIABILITY.  To the extent the Purchaser  deems  necessary,  the
Purchaser has reviewed with the Purchaser's own tax advisors the federal, state,
local and foreign  tax  consequences  of this  investment  and the  transactions
contemplated by this Agreement. The Purchaser relies solely on such advisors and
not on any  statements  or  representations  of  the  Corporation  or any of its
agents.  The Purchaser  understands that the Purchaser (and not the Corporation)
shall be responsible  for the  Purchaser's own tax liability that may arise as a
result of this investment or the transactions contemplated by this Agreement.

         3.8 DISCLOSURE.  To the Purchaser's knowledge, this Agreement, with the
Exhibits hereto, when taken as a whole, does not contain any untrue statement of
a material  fact  concerning  the  Purchaser  or omit to state a  material  fact
necessary in order to make the  statements  concerning  the Purchaser  contained
herein not misleading in light of the circumstances under which they were made.

         3.9   LITIGATION.   There  are  no  actions,   suits,   proceedings  or
investigations  pending  against the  Purchaser  or the  Purchaser's  properties
before any court or governmental agency (nor, to the Purchaser's  knowledge,  is
there any threat thereof) which would impair in any way the Purchaser's  ability
to enter into and fully  perform the  Purchaser's  commitments  and  obligations
under this Agreement or the transactions contemplated hereby.

         3.10 COMPLIANCE  WITH OTHER  INSTRUMENTS.  The execution,  delivery and
performance of and compliance  with this  Agreement,  and the issuance of shares
will not result in any material


                                      -10-

<PAGE>



violation  of, or conflict  with, or constitute a material  default  under,  any
Purchaser's  articles  of  incorporation  or  bylaws  or any of the  Purchaser's
material  agreements nor result in the creation of any mortgage,  pledge,  lien,
encumbrance or charge against any of the assets or properties of the Corporation
or the Shares.

         SECTION 4.  COVENANTS OF  CORPORATION.  The  Corporation  covenants and
agrees with the  Purchaser  that upon the  reasonable  request of the  Purchaser
hereto after the Closing,  the Corporation will take all action and will execute
all documents  and  instruments  necessary or desirable to  consummate  and give
effect to this purchase. These include, by way of illustration and not by way of
limitation, the following:

         4.1 Various conditions relating to filing,  payment,  and collecting of
refunds relating to taxes;

         4.2  Prompt delivery of Corporate books and records;

         4.3  Provisions  relating  to  treatment  of  confidential  proprietary
information obtained in the acquisition process; and

         4.4 Dr. Thomas  Tachovsky  agrees to continue his  employment  with the
Corporation at not less than his present compensation for at least 30 days after
the Closing Date.

         SECTION 5. AGREEMENTS. 5.1 As a material inducement to the Purchaser to
enter into this Agreement and purchase the Shares, the Corporation agrees to:

         5.1.1 provide for the resignation of the current Board of Directors and
the  appointment  of the  Purchaser's  nominees to the Board of Directors of the
Corporation;

         5.1.2 take such actions as are necessary to qualify and  facilitate the
issuance of the Shares  without a shareholder  vote under any applicable law and
the rules and regulations of the applicable Nasdaq market system; and

         5.1.3 provide prompt  reimbursement by the Corporation to the Purchaser
for all reasonable legal and other out-of-pocket expenses incurred in connection
with the completion of this transaction.

         5.1.4  indemnify  the  Purchaser  from and against all losses,  claims,
expenses  and  liabilities  arising  out of any  breach of any  representations,
warranties,  covenants and agreements made by the Corporation in this Agreement.
Purchaser  understands  and agrees  that the  foregoing  indemnification  is the
Purchaser's  sole  and  exclusive  remedy  with  respect  to any  breach  of any
representations, warranties, covenants and agreements made by the Corporation in
this  Agreement,  except to the extent such  breach  could be expected to have a
material adverse effect on the future  operations or financial  condition of the
Corporation.


                                      -11-

<PAGE>



         5.2 As a  material  inducement  to the  Corporation  to enter into this
Agreement and issue the Shares,  the Purchaser agrees to use its best efforts to
cause the  Corporation to maintain  director and officer  liability  coverage in
substantially the same amounts and with substantially the same coverages as that
maintained by the Corporation on the Closing Date for at least three years.

         SECTION  6.  RELEASE.  Dr.  T.  Colin  Campbell,  a  principal  in  the
Purchaser,  agrees not to pursue his claims in C.A. No. 15072 BB in the Court of
Chancery in New Castle County,  State of Delaware (the "Lawsuit").  Dr. Campbell
understands that this Agreement is a full and final release of all claims stated
in the  Lawsuit,  including  any claims which he may have or may contend that he
may have, and Dr. Campbell  further  understands that he is releasing all claims
arising out of or related to the Lawsuit that are known, unknown,  suspected and
unsuspected.

         SECTION 7. CONDITIONS  PRECEDENT TO THE OBLIGATIONS OF PURCHASER.  Each
and every  obligation  of the Purchaser  under this  Agreement is subject to the
condition, at or before the Closing, that the Corporation will have furnished to
the Purchaser a certificate  of an officer of the  Corporation  that its present
legal counsel has been instructed to deliver all files of the Corporation in its
possession  to the  Purchaser  and, to the best of the knowledge of the officer,
all documents of the Corporation have been provided to the Purchaser.

         SECTION 8. CLOSING.

         8.1 TIME, PLACE, AND MANNER OF CLOSING. The closing ("Closing") will be
held at such time and place as the parties may agree,  on January 12,  1998.  At
the time of the  Closing,  the  parties to this  Agreement  will  exchange  such
instruments and documents in order to determine whether the terms and conditions
of this Agreement have been satisfied. Upon the determination of each party that
its conditions to consummate  this purchase have been  satisfied or waived,  the
Corporation  shall deliver to the Purchaser the  certificate(s)  evidencing  the
Shares,  and the Purchaser  shall deliver to the Corporation the monies referred
to in  Section  1.3,  in a manner to be agreed  upon by the  parties.  After the
Closing, the Corporation will execute, deliver, and acknowledge all such further
instruments  of transfer and  conveyance and will perform all such other acts as
the Purchaser may reasonably request to effectively transfer the Shares.

         8.2 CONSUMMATION OF CLOSING.  All acts,  deliveries,  and confirmations
comprising the Closing  regardless of chronological  sequence shall be deemed to
occur  contemporaneously and simultaneously upon the occurrence of the last act,
delivery, or confirmation of the Closing and none of such acts,  deliveries,  or
confirmations  shall be  effective  unless  and until the last of the same shall
have occurred. The time of the Closing has been scheduled to correspond with the
close of business at the principal office of the Corporation and,  regardless of
when the last act,  delivery,  or  confirmation of the Closing shall take place,
the  transfer of the Shares shall be deemed to occur as of the close of business
at the principal office of the Corporation on the date of the Closing.



                                      -12-

<PAGE>



         SECTION 10. MISCELLANEOUS PROVISIONS.

         10.1  AMENDMENT  AND  MODIFICATION.  Subject to  applicable  law,  this
Agreement may be amended,  modified, or supplemented only by a written agreement
signed by the parties.

         10.2 WAIVER OF COMPLIANCE; CONSENTS

         10.2.1  Any  failure  of any  party  to  comply  with  any  obligation,
covenant,  agreement, or condition herein may be waived by the party entitled to
the  performance  of such  obligation,  covenant,  or  agreement  or who has the
benefit of such  condition,  but such  waiver or failure to insist  upon  strict
compliance  with such  obligation,  covenant,  agreement,  or condition will not
operate as a waiver of, or estoppel  with  respect to, any  subsequent  or other
failure.

         10.2.2  Whenever this  Agreement  requires or permits  consent by or on
behalf of any party  hereto,  such consent will be given in a manner  consistent
with the requirements for a waiver of compliance as set forth above.

         SECTION  11.  WAIVER.  Failure  of either  party at any time to require
performance of any provision of this Agreement shall not limit the party's right
to enforce the provision, nor shall any waiver of any breach of any provision be
a waiver of any succeeding  breach of any provision or a waiver of the provision
itself for any other provision.

         SECTION  12. LAW  GOVERNING.  This  Agreement  shall be governed by and
construed in accordance with the laws of the State of North Carolina.

         SECTION 13.  ATTORNEY  FEES. In the event any suit or action is brought
by any party under this Agreement to enforce any of its terms,  or in any appeal
therefrom,  it is  agreed  that  the  prevailing  party  shall  be  entitled  to
reasonable  attorneys  fees to be fixed by the  trial  court,  and/or  appellate
court.

         SECTION 14.  PRESUMPTION.  This Agreement or any section  thereof shall
not be  construed  against any party due to the fact that said  Agreement or any
section thereof was drafted by said party.

         SECTION  15.  COMPUTATION  OF TIME.  In  computing  any  period of time
pursuant to this Agreement,  the day of the act, event or default from which the
designated  period  of time  begins  to run  shall be  included,  unless it is a
Saturday,  Sunday, or a legal holiday,  in which event the period shall begin to
run on the next day which is not a Saturday, Sunday or a legal holiday, in which
event the period shall run until the end of the next day thereafter which is not
a Saturday, Sunday or legal holiday.

         SECTION 15.  TITLES AND  CAPTIONS.  All article,  section and paragraph
titles or captions  contained in this  Agreement  are for  convenience  only and
shall not be deemed  part of the  context or affect the  interpretation  of this
Agreement.


                                      -13-

<PAGE>


         SECTION 16.  PRONOUNS  AND PLURALS.  All  pronouns  and any  variations
thereof shall be deemed to refer to the masculine, feminine, neuter, singular or
plural as the identity of the Person or Persons may require.

         SECTION  17.  ENTIRE  AGREEMENT.  This  Agreement  contains  the entire
understanding   between  and  among  the  parties  and   supersedes   any  prior
understandings  and agreements  among them respecting the subject matter of this
Agreement.

         SECTION 18. AGREEMENT BINDING. This Agreement shall not be binding upon
the successors and assigns of the parties hereto.

         SECTION 19.  FURTHER  ACTION.  The  parties  hereto  shall  execute and
deliver all documents, provide all information and take or forbear from all such
action as may be  necessary  or  appropriate  to achieve  the  purposes  of this
Agreement.

         SECTION 20. GOOD FAITH,  COOPERATION,  AND DUE  DILIGENCE.  The parties
hereto  covenant,  warrant  and  represent  to each other good  faith,  complete
cooperation,  due  diligence  and  honesty  in  fact in the  performance  of all
obligations  of the  parties  pursuant  to  this  Agreement.  All  promises  and
covenants are mutual and dependent.

         SECTION 21.  COUNTERPARTS.  This  Agreement  may be executed in several
counterparts and all so executed shall constitute one Agreement,  binding on all
the  parties  hereto even  though all the  parties  are not  signatories  to the
original or the same counterpart.

         SECTION 22.  PARTIES IN INTEREST.  Nothing herein shall be construed to
be the benefit of any third party,  nor is it intended that any provision  shall
be for the benefit of any third party.

         SECTION 23. SAVINGS CLAUSE. If any provision of this Agreement,  or the
application  of such  provision  to any  person or  circumstance,  shall be held
invalid,  the remainder of this Agreement,  or the application of such provision
to persons  or  circumstances  other than those as to which it is held  invalid,
shall not be affected thereby.


             [The remainder of this page left blank intentionally.]



                                      -14-

<PAGE>


         IN WITNESS WHEREOF,  the parties have executed this Agreement as of the
date and year first written above.


Biomar International, Inc.

By: ______________________
    T. Nelson Campbell
    Chairman of the Board


Paracelsian, Inc.

By:  _________________________________________
         Dr. Thomas Tachovsky
         President and Chief Executive Officer

Agreed and consented to by:

- - ----------------------------
Dr. T. Colin Campbell



                                      -15-

<PAGE>

                                PARACELSIAN, INC.

                               WARRANT CERTIFICATE

JANUARY 14, 1998                                              2,971,429 WARRANTS

                         COMMON STOCK PURCHASE WARRANTS

SECTION 1.     PURCHASE PRICE AND EXERCISE.

         This   Certificate   certifies   that,  for  value   received,   Biomar
International,  Inc. (the "Purchaser"), is the owner of 2,971,429 Warrants, each
of which  Warrants  entitles the owner  thereof to purchase in  increments of at
least one hundred thousand dollars ($100,000)

                                     ONE (1)

fully paid and nonassessable  share subject to adjustment as provided in Section
5 of the Common Stock (the "Common  Stock"),  of  Paracelsian,  Inc., a Delaware
corporation  with its  principal  office in New York (the  "Corporation"),  upon
surrender  of  this  Warrant  Certificate  and  payment  of the  Purchase  Price
specified herein, at the principal office of the Corporation.

         The purchase price per share (the "Purchase  Price") shall initially be
$0.175 per share (the  "Initial  Purchase  Price"),  and the number of shares of
Common Stock  initially  issuable per Warrant  shall be one (1) such share,  all
subject to adjustment as provided in Section 5.

         Warrants may be exercised within 90 days from the date the Common Stock
and these  Warrants are registered  with the Securities and Exchange  Commission
("SEC")  as  provided  under  the  Registration  Rights  Agreement  between  the
Corporation and the Purchaser of even date and are separately transferable, upon
issuance, from shares of Common Stock.

         Upon surrender of this Warrant Certificate, and payment of the Purchase
Price,  the  Corporation  shall issue and cause to be delivered to the holder of
this Warrant  Certificate a certificate for the number of shares of Common Stock
issuable for the Warrants then being exercised.

         Upon any exercise of Warrants evidenced hereby, the form of election to
purchase set forth as Exhibit A shall be properly completed and executed. In the
event that upon any exercise of Warrants evidenced hereby the number of Warrants
exercised  shall be less than the total  number of  Warrants  evidenced  hereby,
there shall be issued to the holder hereof a new Warrant Certificate, evidencing
the number of Warrants not exercised.

SECTION 2.     TRANSFER.

         Upon  surrender  of  this  Warrant   Certificate  and  similar  Warrant
Certificates at the


<PAGE>



principal office of the transfer agent of the Corporation,  by the holder hereof
in  person  or  by  an  attorney  duly  authorized  in  writing,   such  Warrant
Certificates may be transferred or exchanged in minimum quantities of fifty (50)
Warrants, in the manner provided in this Warrant Certificate and without payment
of any service charge, for another Warrant  Certificate or Warrant  Certificates
of like tenor,  evidencing in the aggregate the number of Warrants  evidenced by
the Warrant  Certificates  so surrendered and registered in the name or names as
requested by the then registered owner thereof or by an attorney duly authorized
in writing.  The form of election to transfer  set forth as Exhibit B,  properly
completed and executed, may be used for this purpose.

         Warrants are, upon issuance, separately transferable from any shares of
Common Stock issued by the Corporation.

SECTION 3.     DURATION.

         Warrants may be exercised within 90 days from the date the Common Stock
and  these  Warrants  are  registered  with the SEC,  subject  to the  terms and
conditions   hereof,  at  which  time  all  rights  evidenced  by  this  Warrant
Certificate  shall cease and the Warrants shall become void,  subject to earlier
termination as described in Section 8.

SECTION 4.     MUTILATED OR MISSING WARRANT CERTIFICATE.

         In the event that this Warrant  Certificate  shall be mutilated,  lost,
stolen, or destroyed, the Corporation may, in its discretion,  issue and deliver
in exchange and substitution for and upon  cancellation of the mutilated Warrant
Certificate,  or in  lieu  of and in  substitution  for  the  lost,  stolen,  or
destroyed  Warrant  Certificate,  a new  Warrant  Certificate  of like tenor and
evidencing  the number of  Warrants  evidenced  by the  Warrant  Certificate  so
mutilated,  lost,  stolen,  or  destroyed,  but only upon  receipt  of  evidence
satisfactory  to the  Corporation.  The  applicant for such  substitute  Warrant
Certificate  shall also comply with such other  reasonable  regulations  and pay
such  other  reasonable  charges  as the  Corporation  may,  from  time to time,
prescribe.

SECTION 5.     ADJUSTMENTS TO PURCHASE PRICE AND NUMBER OF SHARES ISSUABLE UNDER
               WARRANTS.

         The Purchase  Price and the resulting  number of shares of Common Stock
issuable under each Warrant shall be subject to adjustment as follows:

         (a) If the Corporation  after the date of this Warrant  Certificate but
before its exercise:

                  (1) pays a  dividend  or any  other  distribution  payable  in
                  shares of its Common Stock  otherwise  than out of earnings or
                  earned surplus;

                  (2) subdivides its outstanding  shares of Common Stocks into a
                  greater number


<PAGE>

                  of shares;

                  (3)  combines  its  outstanding  shares of Common Stock into a
                  smaller number of shares;

                  (4) issues by  reclassification  of its shares of Common Stock
                  any shares of capital stock of the  Corporation  (other than a
                  change  in par value or from par value to no par value or from
                  no par value to par value); or

                  (5) issues rights,  options or warrants  entitling  holders of
                  shares of Common Stock to subscribe for shares of Common Stock
                  at less than the current market price, if any;

the Purchase Price in effect  immediately prior to such action shall be adjusted
so that the holder of each  Warrant  may  receive the number of shares of Common
Stock of the  Corporation  to which it would have been entitled upon such action
if such  holder had so  exercised  the Warrant  immediately  prior  thereto.  An
adjustment  made pursuant to this Section 5 shall become  effective  immediately
after the record date for the  determination  of owners of Common Stock entitled
thereto in the case of a dividend or  distribution,  and shall become  effective
immediately after the effective date in the case of a subdivision,  combination,
reclassification, or issuance of rights, options or warrants.

         (b) No  payment  or  adjustment  shall be made by or on  behalf  of the
Corporation on account of any cash dividends on the Common Stock issued upon any
exercise of a Warrant  which was  declared  for payment to the holders of Common
Stock  of  record  as of a date  prior  to the date on  which  such  Warrant  is
exercised.

         (c) Upon each  adjustment  of the Purchase  Price made pursuant to this
Section  5, each  Warrant  shall  thereafter  (until  another  such  adjustment)
evidence the right to purchase that number of shares of Common Stock (calculated
to the nearest hundredth) obtained by dividing the Initial Purchase Price by the
Purchase Price in effect after such adjustment.

         (d) Whenever  there is an adjustment in the Purchase  Price as provided
in this Section 5, the  Corporation  shall promptly cause a notice to be sent by
registered  or  certified  mail,  postage  prepaid,  to each holder of a Warrant
Certificate,  such notice  stating that such  adjustment  has been  effected and
stating  the  Purchase  Price  then in effect and the number of shares of Common
Stock issuable per Warrant as a result of such adjustment.

         (e)  The  Corporation  shall  reserve  and  keep  available  out of its
authorized  Common Stock and/or shares of its Common Stock then owned or held by
or for the account of the  Corporation,  solely for the purpose of delivery upon
exercise of the  Warrants as  provided  herein,  such number of shares of Common
Stock equal to the number of shares of Common Stock  issuable  upon  exercise of
all  Warrants  then  outstanding.  All shares of Common  Stock which shall be so
delivered upon such exercise shall be duly and validly issued and fully paid


<PAGE>



and nonassessable.

         (f) To the extent  that there are not  sufficient  shares of the Common
Stock  available to satisfy the  requirements  under  Paragraph  (e) above,  the
Corporation  shall use its best  efforts to obtain  shareholder  approval  of an
increase in the authorized  number of shares in an amount  sufficient to satisfy
the  deficiency in the number of shares.  The Purchaser  agrees and  understands
that these  Warrants may be exercised  only for the number of authorized  shares
available.

SECTION 6.     FRACTIONAL SHARES.

         As provided in Section 1 above,  each Warrant shall  initially  entitle
the holder  thereof to purchase  one (1) share of Common Stock upon the exercise
thereof,  but the number of shares of Common Stock  purchasable upon exercise of
each Warrant  shall be subject to  adjustment,  as provided in Section 5 hereof,
and  accordingly  the number of shares of Common Stock issuable upon exercise of
each Warrant may be expressed to include fractional  shares.  Upon exercise of a
Warrant,  the Corporation will not be obligated to issue fractional  shares, but
the number of  Warrants  being  exercised  at any one time by the holder will be
aggregated and multiplied by the number of shares of Common Stock issuable under
each Warrant (subject to the terms and conditions  hereof).  The total number of
full shares of Common Stock  issuable  under the total number of Warrants  being
exercised  at any one time by the holder  (subject  to the terms and  conditions
hereof)  will  forthwith  be issued to such holder,  and the  Corporation  shall
thereupon pay the cash value of any fractional  share of Common Stock at a price
equal to the product of (a) such  fraction of a share of Common  Stock,  and (b)
the Purchase Price as last adjusted.

SECTION 7.     NOTICES TO WARRANT HOLDER.

         Nothing  contained  in this Warrant  Certificate  shall be construed as
conferring  upon the holder hereof the right to vote or to consent or to receive
notice as a  stockholder  in  respect of the  meetings  of  stockholders  or the
election of  directors of the  Corporation  or any other  matter,  or any rights
whatsoever to which a stockholder of the Corporation may be entitled.

         In case the Corporation shall enter into any agreement or understanding
or the Board of Directors  shall adopt any  resolution  authorizing or proposing
any transaction of the type described in Section 8 hereof,  or with respect to a
voluntary  or  involuntary  dissolution,   liquidation  or  winding  up  of  the
Corporation,  then in any such event the Corporation  promptly shall cause to be
mailed, by registered or certified mail, postage prepaid,  to the holder of this
Warrant  certificate  at such holder's last address  appearing on the records of
the  Corporation at least thirty (30) days prior to such event, a notice stating
the expected  record date for  determining  holders of Common Stock  entitled to
exchange  their  shares with  respect to a  transaction  described  in Section 8
hereof, or the date on which such dissolution,  liquidation or winding up of the
Corporation is expected to occur; provided,  however, that the Corporation shall
not be liable or  responsible  if the actual  dates of any such events  shall be
different from the expected dates set forth in such notice.



<PAGE>



SECTION 8.     TERMINATION  OF  RIGHT OF  CONVERSION  ON  FUNDAMENTAL  CORPORATE
               CHANGES.

         Notwithstanding  anything  herein to the  contrary,  and subject to the
notice  requirements of Section 7 hereof, if the Corporation shall be a party to
any transaction  which involves any  consolidation  or merger of the Corporation
with, or any sale of all or  substantially  all of the assets of the Corporation
to, another  corporation,  which corporation does not control, is not controlled
by, and is not under common control with the Corporation,  and which transaction
is effected  in such a way that the holder of Common  Stock shall be entitled to
receive  stock,  securities  or other  assets with respect to or in exchange for
Common  Stock,  then the right to exercise  the Warrants and thereby to purchase
shares of Common  Stock shall  terminate at the close of business on the date as
of which the  holders of Common  Stock of record  shall be  entitled to exchange
their shares of Common Stock for  securities  or other assets  deliverable  upon
such consolidation, merger or sale.

SECTION 9.     NOTICES.

         Any notice to be given by the holder of this Warrant Certificate to the
Corporation shall be considered  sufficiently given if sent by first-class mail,
postage prepaid, addressed as follows:

                           Paracelsian, Inc.
                           95 Brown Road
                           Ithaca, New York 14850
                           Attn:  Chief Financial Officer

or such  other  address as the  Corporation  might  designate  in writing to the
holder.

         Any notice to be given to a holder of this Warrant  Certificate  by the
Corporation  shall be  considered  sufficiently  given if sent by  registered or
certified mail,  postage  prepaid,  return receipt  requested,  addressed to the
address of such  holder as it appears on the  records of the  Corporation.  Such
records of the Corporation  will be revised by the Corporation upon receipt of a
written notice from such holder specifying a new address.

SECTION 10.    SUPPLEMENTS AND AMENDMENTS.

         The  Corporation  may,  from  time to time,  supplement  or amend  this
Warrant  Certificate  without the approval of the holder hereof in order to cure
any ambiguity or to correct or supplement any provision  contained  herein which
may be defective or  inconsistent  with any other provision  herein,  or to make
changes  in any other  provisions  in regard to  matters  or  questions  arising
hereunder which the Corporation may deem necessary and desirable,  provided that
no supplement or amendment shall adversely affect the interests of the holder.



<PAGE>



SECTION 11.    SUCCESSORS.

         All of the provisions of this Warrant Certificate by or for the benefit
of the  Corporation  shall bind and inure to the benefit of its  successors  and
assigns.

SECTION 12.    GOVERNING LAW.

         This Warrant  Certificate  shall be deemed to be a contract  made under
the laws of the State of Delaware  and for all  purposes  shall be  construed in
accordance with such laws.

         IN  WITNESS  WHEREOF,  Paracelsian,   Inc.,  has  caused  this  Warrant
Certificate to be signed by its President and its corporate seal to be impressed
hereon attested to by the signature of its Secretary.

Dated:  January 12, 1998

                                       PARACELSIAN, INC.


                                       By:______________________________________
                                          Dr. Thomas Tachovsky
                                          President and Chief Executive Officer


[Corporate Seal]

Attest:


_____________ Secretary



<PAGE>

                                    Exhibit A

                              ELECTION TO PURCHASE

TO:      PARACELSIAN, INC.
         222 Langmuir Laboratories
         Ithaca, New York 14850
         Attn:  Chief Financial Officer

         The undersigned hereby irrevocably elects to exercise  ________________
Warrants  represented by the attached Warrant  Certificate,  and to purchase the
shares of Common Stock issuable upon the exercise of said Warrants, and requests
that certificates for such shares be issued in the name of


- - --------------------------------------------------------------------------------
                                     (name)

- - --------------------------------------------------------------------------------
                                    (address)

- - --------------------------------------------------------------------------------
                                (Taxpayer number)
and be delivered to

 ................................................................................
                                     (name)
 ................................................................................
                                    (address)

and, if said number of Warrants  shall not be all the Warrants  evidenced by the
attached  Warrant  Certificate,  that a new Warrant  Certificate for the balance
remaining  of such  Warrants  be issued in the name of,  and  delivered  to, the
undersigned at the address stated below.

Payment is to be made as follows:

         Cash.......................................................$___________

Name of holder of Warrant Certificate:


____________________________________
          (Please print)

Address:  __________________________

          __________________________


Signature:__________________________


NOTE: The above signature must correspond with the name as written upon the face
of  this  Warrant  Certificate  in  every  particular,   without  alteration  or
enlargement or any change.


<PAGE>


EXHIBIT B

                                   ASSIGNMENT

         FOR VALUE  RECEIVED  the  undersigned  hereby  sell(s),  assign(s)  and
transfer(s)
to______________________________________________________________________________
________________________________________________________________________________
(Please print or type name and address, including zip code, of assignee)

PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF
ASSIGNEE:____________________________

________________________  Common  Stock  purchase  Warrants  represented  by the
attached    Certificate,    and   do   hereby    irrevocably    constitute   and
appoint:____________________,  Attorney,  to transfer said Warrants on the books
of the within named corporation with full power of substitution in the premises.

Dated:__________________________________

Sign Here:______________________________

Notice:  The  signature  to this  assignment  must  correspond  with the name as
written upon the face of the certificate in every particular, without alteration
or enlargement or any change.

SIGNATURE GUARANTEED


_________________________________________
Notice:  Signature(s) must be guaranteed.

         The following  abbreviations,  when used in the inscription on the face
of this certificate,  shall be construed as though they were written out in full
according to applicable laws or regulations:

TEN COM--as  tenants in common
TEN ENT--as  tenants by the entireties 
JT TEN--as joint tenants with right of
        survivorship and not as tenants
        in common
UNIF GIFT MIN ACT--Uniform Gifts to Minors Act ___________
CUST--custodian                                  (State)

Additional abbreviations may also be used although not listed above.


<PAGE>

                          REGISTRATION RIGHTS AGREEMENT

         This Registration  Rights Agreement,  dated as of January 14, 1998 (the
"Agreement"),  is by and between PARACELSIAN,  INC., a Delaware corporation with
its principal  offices in New York (the  "Company"),  and BIOMAR  INTERNATIONAL,
INC., a Delaware  corporation with its principal  offices in North Carolina (the
"Investor").

                                   WITNESSETH:

         WHEREAS,  pursuant  to the  terms of a Stock  Purchase  Agreement  (the
"Purchase  Agreement"),  dated the date  hereof,  between  the  Company  and the
Investor,  the Investor is investing in newly issued  shares of the common stock
of the Company;

         WHEREAS, it is a condition to the obligations of the Investor under the
Purchase  Agreement that this Agreement be executed by the parties  hereto,  and
the  parties  are  willing  to  execute  this  Agreement  and to be bound by the
provisions hereof;

         NOW, THEREFORE,  in consideration of the foregoing,  the agreements set
forth below,  and the parties'  desire to provide for continuity of ownership of
the Company to further the  interests  of the Company and its present and future
stockholders, the parties hereby agree with each other as follows:

         1. CERTAIN DEFINITIONS.  As used in this Agreement, the following terms
shall have the following respective meanings:

         "Commission" shall mean the Securities and Exchange Commission,  or any
other federal agency at the time administering the Securities Act.

         "Common  Stock"  shall  mean  the  common  stock  of  the  Company,  as
constituted as of the date of this Agreement.

         "Exchange  Act"  shall mean the  Securities  Exchange  Act of 1934,  as
amended,  or any similar federal  statute,  and the rules and regulations of the
Commission thereunder, all as the same shall be in effect at the time.

         "Holder"  shall mean an Investor  owning or having the right to acquire
Restricted  Stock or any transferee of rights under this Agreement under Section
13.

         "Registration  Expenses" shall mean all expenses incurred in connection
with a registration statement,  including,  without limitation, all registration
and filing  fees,  printing  expenses,  fees and  disbursements  of counsel  and
independent  public  accountants for the Company,  fees and expenses  (including
counsel fees) incurred in connection with complying with


                                        1

<PAGE>

state  securities  or "blue  sky"  laws,  fees of the  National  Association  of
Securities   Dealers,   Inc.,  transfer  taxes,  fees  of  transfer  agents  and
registrars,  costs of insurance,  and fees and  disbursements of one counsel for
the sellers of Restricted Stock, but excluding any Selling Expenses.

         "Restricted  Stock" shall mean the mean the  "Shares,"  the  "Warrants"
(both as defined in the  Purchase  Agreement)  and the Common Stock to be issued
under the Warrants.

         "Securities Act" shall mean the Securities Act of 1933, as amended,  or
any similar  federal  statute,  and the rules and  regulations of the Commission
thereunder, all as the same shall be in effect at the time.

         "Selling  Expenses" shall mean all  underwriting  discounts and selling
commissions  applicable  to the sale of  Restricted  Stock which are incurred in
connection  with a  registration  statement,  plus any  portion of  Registration
Expenses required by law to be paid by the selling shareholder.

         2. RESTRICTIVE LEGEND. Each certificate  representing  Restricted Stock
shall be stamped  or  otherwise  imprinted  with a legend  substantially  in the
following form:

         THIS CERTIFICATE HAS NOT BEEN REGISTERED UNDER THE SECURITIES
         ACT  OF  1933.  THE   CORPORATION   WILL  NOT  TRANSFER  THIS
         CERTIFICATE  UNLESS  (i) THERE IS AN  EFFECTIVE  REGISTRATION
         COVERING THE SHARES REPRESENTED BY THIS CERTIFICATE UNDER THE
         SECURITIES  ACT OF 1933 AND ALL APPLICABLE  STATE  SECURITIES
         LAWS,  (ii) IT  FIRST  RECEIVES  A LETTER  FROM AN  ATTORNEY,
         ACCEPTABLE  TO THE BOARD OF DIRECTORS OR ITS AGENTS,  STATING
         THAT IN THE OPINION OF THE ATTORNEY THE PROPOSED  TRANSFER IS
         EXEMPT FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933 AND
         UNDER ALL  APPLICABLE  STATE  SECURITIES  LAWS,  OR (iii) THE
         TRANSFER IS MADE  PURSUANT  TO RULE 144 UNDER THE  SECURITIES
         ACT OF 1933.

         3. NOTICE OF PROPOSED  TRANSFER.  Prior to any proposed transfer of any
Restricted  Stock or other  shares of capital  stock of the Company  (other than
under the circumstances  described in Sections 4 or 5), the Holder thereof shall
give written  notice to the Company of its  intention  to effect such  transfer.
Each such notice  shall  describe the manner of the  proposed  transfer  and, if
requested  by the  Company,  shall  be  accompanied  by an  opinion  of  counsel
reasonably  satisfactory to the Company to the effect that the proposed transfer
may be effected  without  registration  under the Securities Act,  whereupon the
Holder of such stock shall be entitled to transfer such stock in accordance with
the terms of its notice; PROVIDED, HOWEVER, that

                                   2

<PAGE>

no such  opinion  of counsel  shall be  required  for a transfer  to one or more
partners of the transferor  (in the case of a transferor  that is a partnership)
or to a parent corporation,  subsidiary corporation or to a corporation which is
under common  control with a transferor  (in the case of a transferor  that is a
corporation,  to  a  member  of  the  transferor's  immediate  family  or  other
descendant  of the  transferor  or to a trust or other entity for the benefit of
the transfer  and/or such person  provided  that in such case the  transferee(s)
remain bound hereby).

         4. REQUIRED  REGISTRATION.  (a) At any time within six months following
the date of this Agreement, one or more Holders of Restricted Stock constituting
at least  sixty  percent  (60%) of the total  shares of  Restricted  Stock  then
outstanding  may request the Company to register under the Securities Act all or
any portion of the shares of Restricted Stock held by such requesting  Holder or
Holders ("Initiating Holders").

         (b) Notwithstanding  anything to the contrary contained in this Section
4, no request may be made under this  Section 4 within one hundred  eighty (180)
days after the effective date of a registration  statement  filed by the Company
other than on Form S-4 or S-8 or their successor forms.

         (c) If at the time of any request to register Restricted Stock pursuant
to this Section 4 (i) the Company is engaged or has fixed plans to engage within
sixty (60) days of the time of the request in a  registered  public  offering of
its  securities,  (ii) the  Company  is in  possession  of  material  non-public
information the public  disclosure of which, in the good faith  determination of
the Company's  Board of Directors,  would  materially  and adversely  affect the
Company,  (iii) the Company  shall have  delivered to the Holders of  Restricted
Stock that have  requested a  registration  a  certificate  of an officer of the
Company to the effect that, on the advice of counsel,  the Company believes such
delay is necessary to comply with  Regulation M under the Exchange  Act, or (iv)
the  Company  is  engaged  in  any  other  activity  which,  in the  good  faith
determination of the Company's Board of Directors,  would be adversely  affected
by the requested registration to the material detriment of the Company, then the
Company may at its option  direct that such  request be delayed for a reasonable
period  not in excess of one  hundred  twenty  (120)  days from the time of such
request to  register  Restricted  Stock  pursuant to this  Section 4;  provided,
however,  that such right to delay a request may be exercised by the Company not
more than once in any twelve-month period. Such delay, however, shall not in any
way restrict the Holders from  exercising  piggyback  registration  rights under
Section 5 during such period.

         (d)  Following  receipt of any notice under this Section 4, the Company
shall  immediately  notify all Holders of Restricted  Stock from whom notice has
not been  received,  and such Holders shall be entitled  within thirty (30) days
thereafter to request the Company to include in the requested  registration  all
or any portion of their shares of  Restricted  Stock.  The Company shall use its
best efforts to register under the Securities Act, for public sale in accordance
with the method of disposition  specified in the notice from requesting Holders,
the number of shares of  Restricted  Stock  specified in such notice (and in all
notices received by the Company from other Holders within thirty (30) days after
the giving of such notice by the


                                        3

<PAGE>

Company).  If  such  method  of  disposition  shall  be an  underwritten  public
offering, the Holders of a majority of the shares of Restricted Stock to be sold
in such  offering may  designate  the  managing  underwriter  of such  offering,
subject to the approval of the Company, which approval shall not be unreasonably
withheld or delayed.  Notwithstanding  any other provision of this Section 4, if
the underwriter advises the Initiating Holders in writing that marketing factors
require a  limitation  of the  number of  shares  to be  underwritten,  then the
Initiating  Holders shall so advise all Holders of Restricted  Stock which would
otherwise  be  underwritten  pursuant  hereto,  and  the  number  of  shares  of
Restricted  Stock that may be included in the  underwriting  shall be  allocated
among all Holders thereof,  including the Initiating  Holders, in proportion (as
nearly as practicable) to the amount of Restricted Stock of the Company owned by
each Holder; PROVIDED, HOWEVER, that the number of shares of Restricted Stock to
be  included  in  such  underwriting  shall  not be  reduced  unless  all  other
securities are first entirely excluded from the underwriting.

         (e) The  Company  shall  be  obligated  to  register  Restricted  Stock
pursuant to this Section 4, on only one (1) occasion;  PROVIDED,  HOWEVER,  that
such  obligation  shall be deemed  satisfied only when a registration  statement
covering  all  shares of  Restricted  Stock  specified  in notices  received  as
aforesaid,  for sale in accordance  with the method of disposition  specified by
the  requesting  Holders  shall have  become  effective  and,  if such method of
disposition is a firm commitment  underwritten public offering,  all such shares
shall have been sold pursuant thereto, unless a failure was caused by a Holder.

         (f)  Except  for  registration  statements  on  Form  S-4,  S-8  or any
successor  forms thereto,  and unless the Company (i) has  previously  given the
notice  referred  to in  Section 5 or (ii) has  exercised  its rights to delay a
requested  registration  under  Section  4(c)(i)  and  within  the  time  period
prescribed  in Section  4(c) files a  registration  statement  with respect to a
registered public offering of it securities,  the Company will not file with the
Commission any other registration  statement with respect to a registered public
offering of its  securities,  the Company will not file with the  Commission any
other  registration  statement  under the  Securities Act with respect to Common
Stock, whether for its own account or that of other stockholders,  from the date
of receipt of a notice from requesting  Holders pursuant to this Section 4 until
the completion of the period of  distribution of the  registration  contemplated
thereby.

         5. PIGGYBACK  REGISTRATION.  (a) If the Company at any time (other than
pursuant to Section 4 or Section 13) proposes to register any of its  securities
under the Securities Act for sale to the public,  whether for its own account or
for the  account of other  security  holders  or both  (except  with  respect to
registration  statements on Forms S-4, S-8 or any successor forms thereto), each
such time it will give written notice to all Holders of  outstanding  Restricted
Stock of its intention so to do;  PROVIDED  HOWEVER that no such notice shall be
required  after  such  time  that  the  Company  ceases  to  have   registration
obligations  under this Section 5. Upon the written  request of any such Holder,
received by the Company within ten (10) days after the giving of any such notice
by the Company,  to register any of its  Restricted  Stock (which  request shall
state the intended method of disposition thereof), the Company will use its best
efforts to cause the Restricted Stock as to which  registration  shall have been
so requested to be included in the


                                        4

<PAGE>


securities to be covered by the registration  statement  proposed to be filed by
the Company,  all to the extent required to permit the sale or other disposition
by the Holder (in accordance with its written  request) of such Restricted Stock
so registered.

         (b) If any  registration  pursuant to this Section 5 shall be, in whole
or in part,  an  underwritten  public  offering of Common  Stock,  the number of
shares of Restricted Stock to be included in such an underwriting may be reduced
pro rata  among  the  requesting  Holders  based  upon the  number  of shares of
Restricted  Stock owned by such  Holders if and to the extent that the  managing
underwriter  shall be of the opinion that such inclusion would adversely  affect
the  marketing of the  securities to be sold by the Company  therein;  PROVIDED,
HOWEVER,  that:  (1) if the Company  registers any of its securities for its own
account in such  underwriting,  such number of shares of Restricted  Stock shall
not be reduced if any shares are to be  included  in such  underwriting  for the
account of any person other than the Company or requesting Holders of Restricted
Stock or (2) if the Company does not register any of its  securities for its own
account in such  underwriting,  the number of shares of  Restricted  Stock to be
included in such  underwriting  shall not be reduced unless all other securities
are first  entirely  excluded from the  underwriting  unless the Holders of more
than 60% of the  Restricted  Securities  consent to the  inclusion of such other
securities.

         (c)  Notwithstanding  the  foregoing  provisions of this Section 5, the
Company may withdraw any  registration  statement  referred to in this Section 5
without thereby incurring any liability to the Holders of Restricted Stock.

         6. OBLIGATIONS OF THE COMPANY.  If and whenever the Company is required
by the  provisions  of  Section 4 or 5 to use its best  efforts  to  effect  the
registration  of any shares of Restricted  Stock under the  Securities  Act, the
Company will, as expeditiously as possible:

         (a)  prepare  and file with the  Commission  a  registration  statement
(which,  in the case of an underwritten  public offering  pursuant to Section 4,
shall be on Form S-1 or other form of general applicability  satisfactory to the
managing  underwriter  selected  as  therein  provided)  with  respect  to  such
securities  and use its best  efforts to cause such  registration  statement  to
become and remain  effective  for the  period of the  distribution  contemplated
thereby (determined as hereinafter provided);

         (b)  prepare  and  file  with  the  Commission   such   amendments  and
supplements to such registration statement and the prospectus used in connection
therewith  as may be  necessary to keep such  registration  statement  effective
until completion of the period of distribution and comply with the provisions of
the  Securities  Act with respect to the  disposition  of all  Restricted  Stock
covered by such registration  statement in accordance with the sellers' intended
method of disposition set forth in such registration statement for such period;

         (c) furnish to each seller of Restricted  Stock and to each underwriter
such number of copies of the registration  statement and the prospectus included
therein  (including each preliminary  prospectus) as such person  reasonably may
request in order to facilitate the public


                                        5

<PAGE>

sale or other  disposition of the Restricted Stock covered by such  registration
statement;

         (d) use its best  efforts to register or qualify the  Restricted  Stock
covered by such  registration  statement under the securities or "blue sky" laws
of such  jurisdictions  as the sellers of Restricted Stock or, in the case of an
underwritten public offering, the managing underwriter reasonably shall request;
PROVIDED,  HOWEVER,  that the Company shall not for any such purpose be required
to qualify  generally  to  transact  business  as a foreign  corporation  in any
jurisdiction  where it is not so qualified  or to consent to general  service of
process in any such jurisdiction;

         (e) use its best efforts to list the  Restricted  Stock covered by such
registration statement with any securities exchange on which the Common Stock of
the Company is then listed;

         (f)  immediately  notify  each  seller  of  Restricted  Stock  and each
underwriter  under such  registration  statement,  at any time when a prospectus
relating  thereto is required to be delivered  under the Securities  Act, of the
happening  of any event of which the Company has  knowledge as a result of which
the  prospectus  contained in such  registration  statement,  as then in effect,
includes  an untrue  statement  of a material  fact or omits to state a material
fact required to be stated therein or necessary to make the  statements  therein
not misleading in light of the circumstances then existing;

         (g) if the offering is underwritten and at the request of any seller of
Restricted  Stock,  use its best efforts to furnish on the date that  Restricted
Stock is delivered to the underwriters  for sale pursuant to such  registration:
(i) an opinion  dated  such date of counsel  representing  the  Company  for the
purposes of such registration, addressed to the underwriters and to such seller,
stating  that  such  registration  statement  has  become  effective  under  the
Securities Act and that (A) to the best knowledge of such counsel, no stop order
suspending the effectiveness thereof has been issued and no proceedings for that
purpose have been instituted or are pending or contemplated under the Securities
Act, (B) the registration  statement,  the related prospectus and each amendment
or  supplement  thereof  comply  as to form in all  material  respects  with the
requirements  of the  Securities  Act (except that such counsel need not express
any opinion as to financial  statements contained therein) and (C) to such other
effects as  reasonably  may be requested by counsel for the  underwriters  or by
such  seller  or its  counsel,  and  (ii) a  letter  dated  such  date  from the
independent  public  accountants  retained  by  the  Company,  addressed  to the
underwriters  and to such  seller,  stating  that  they are  independent  public
accountants within the meaning of the Securities Act and that, in the opinion of
such  accountants,  the  financial  statements  of the  Company  included in the
registration  statement  or the  prospectus,  or  any  amendment  or  supplement
thereof,  comply  as to  form  in all  material  respects  with  the  applicable
accounting   requirements   of  the  Securities   Act,  and  such  letter  shall
additionally cover such other financial matters (including information as to the
period  ending  no more than five (5)  business  days  prior to the date of such
letter) with respect to such  registration as such  underwriters  reasonably may
request; and

         (h) make available for  inspection by each seller of Restricted  Stock,
any


                                        6

<PAGE>


underwriter  participating  in any  distribution  pursuant to such  registration
statement,  and any attorney,  accountant or other agent retained by such seller
or underwriter,  all financial and other records,  pertinent corporate documents
and properties of the Company,  and cause the Company's officers,  directors and
employees  to supply all  information  reasonably  requested by any such seller,
underwriter,  attorney, accountant or agent in connection with such registration
statement,  subject to each  party's  obligations  not to disclose or misuse any
confidential information disclosed to it.

         For  purposes  of  Sections   4(f),   6(a)  and  6(b),  the  period  of
distribution  of  Restricted  Stock  in a firm  commitment  underwritten  public
offering  shall be deemed to extend until each  underwriter  has  completed  the
distribution  of all securities  purchased by it, and the period of distribution
of Restricted  Stock in any other  registration  shall be deemed to extend until
the earlier of the sale of all Restricted  Stock covered  thereby and sixty (60)
days after the effective date thereof.

         7.  OBLIGATIONS  OF  SELLING  STOCKHOLDERS.  In  connection  with  each
registration  hereunder,  the sellers of  Restricted  Stock will  furnish to the
Company in writing such  information with respect to themselves and the proposed
distribution by them as reasonably shall be necessary to assure  compliance with
federal and applicable state securities laws.

         8. CERTAIN  UNDERWRITING  MATTERS. In connection with each registration
pursuant hereto covering an underwritten  public offering,  the Company and each
seller agree to enter into a written  agreement  with the  managing  underwriter
selected  in the  manner  herein  provided  in such  form  and  containing  such
provisions as are customary in the  securities  business for such an arrangement
between such  underwriter  and  companies of the Company's  size and  investment
stature.

         9.  EXPENSES.  The  Company  will  pay  all  Registration  Expenses  in
connection with each registration statement hereunder.

         10.   INDEMNIFICATION   AND  CONTRIBUTION.   (a)  In  the  event  of  a
registration  of any of the  Restricted  Stock under the Securities Act pursuant
hereto, the Company will and hereby does indemnify and hold harmless each seller
of such Restricted Stock  thereunder,  each underwriter of such Restricted Stock
thereunder  and  each  other  person,  if  any,  who  controls  such  seller  or
underwriter  within the  meaning of the  Securities  Act,  against  any  losses,
claims,  damages  or  liabilities,  joint  or  several,  to which  such  seller,
underwriter or controlling person may become subject under the Securities Act or
otherwise, insofar as such losses, claims, damages or liabilities (or actions in
respect  thereof) arise out of or are based upon any untrue statement or alleged
untrue  statement of any material fact contained in any  registration  statement
under  which such  Restricted  Stock was  registered  under the  Securities  Act
pursuant  hereto,  any  preliminary  prospectus  or final  prospectus  contained
therein,  or any amendment or supplement  thereof,  or arise out of or are based
upon the omission or alleged  omission to state therein a material fact required
to be stated therein or necessary to make the statements therein not misleading,
and will  reimburse  each  such  seller,  each  such  underwriter  and each such
controlling person for any legal


                                        7

<PAGE>


or other expenses  reasonably  incurred by them in connection with investigating
or  defending  any such loss,  claim,  damage,  liability  or action,  PROVIDED,
HOWEVER,  that the  Company  will not be  liable  in any such case if and to the
extent that any such loss, claim,  damage or liability arises out of or is based
upon an untrue  statement  or alleged  untrue  statement  or omission or alleged
omission so made in conformity  with  information  furnished by any such seller,
any such underwriter or any such controlling person in writing  specifically for
use in such registration statement or prospectus.

         (b) In the event of a registration of any of the Restricted Stock under
the  Securities  Act  pursuant  hereto,  each  seller of such  Restricted  Stock
thereunder  severally  and not jointly,  will  indemnify  and hold  harmless the
Company, each person, if any, who controls the Company within the meaning of the
Securities  Act,  each  officer  of  the  Company  who  signs  the  registration
statement,  each director of the Company, each other seller of Restricted Stock,
each underwriter and each person who controls any underwriter within the meaning
of the Securities Act, against all losses, claims, damages or liabilities, joint
or  several,  to which the  Company or such  officer,  director,  other  seller,
underwriter or controlling person may become subject under the Securities Act or
otherwise, insofar as such losses, claims, damages or liabilities (or actions in
respect  thereof) arise out of or are based upon any untrue statement or alleged
untrue  statement of any material fact contained in the  registration  statement
under  which such  Restricted  Stock was  registered  under the  Securities  Act
pursuant  hereto,  any  preliminary  prospectus  or final  prospectus  contained
therein,  or any amendment or supplement  thereof,  or arise out of or are based
upon the omission or alleged  omission to state therein a material fact required
to be stated therein or necessary to make the statements  therein no misleading,
and will  reimburse the Company and each such officer,  director,  other seller,
underwriter  and controlling  person for any legal or other expenses  reasonably
incurred by them in connection  with  investigating  or defending any such loss,
claim, damage, liability or action, PROVIDED,  HOWEVER, that such seller will be
liable  hereunder in any such case if and only to the extent that any such loss,
claim, damage or liability arises out of or is based upon an untrue statement or
alleged untrue  statement or omission or alleged  omission made in reliance upon
and in conformity with information pertaining to such seller, as such, furnished
in  writing  to the  Company  by  such  seller  specifically  for  use  in  such
registration statement or prospectus, and PROVIDED FURTHER that the liability of
each seller hereunder shall not apply to amounts paid in settlement without such
seller's prior written consent.

         (c) Promptly after receipt by an indemnified  party hereunder of notice
of the commencement of any action,  such indemnified  party shall, if a claim in
respect thereof is to be made against the indemnifying  party hereunder,  notify
the  indemnifying  party in writing  thereof,  but the omission so to notify the
indemnifying  party shall not relieve it from any liability which it may have to
such indemnified party other than under this Section 10 and shall only relive it
from any  liability  which  it may have to such  indemnified  party  under  this
Section 10 if and to the extent the  indemnifying  party is  prejudiced  by such
omission. In case any such action shall be brought against any indemnified party
and it shall notify the  indemnifying  party of the  commencement  thereof,  the
indemnifying  party shall be entitled  to  participate  in and, to the extent it
shall  wish,  to  assume  and   undertake  the  defense   thereof  with  counsel
satisfactory


                                        8

<PAGE>

to such indemnified party, and, after notice from the indemnifying party to such
indemnified  party of its  election  so to  assume  and  undertake  the  defense
thereof,  the indemnifying  party shall not be liable to such indemnified  party
under  this  Section 10 for any legal  expenses  subsequently  incurred  by such
indemnified  party in connection  with the defense thereof other than reasonable
costs of  investigation  and of  liaison  with  counsel so  selected,  PROVIDED,
HOWEVER, that, if the defendants in any such action include both the indemnified
party and the indemnifying party and the indemnified party shall have reasonably
concluded  that  there  may be  reasonable  defenses  available  to it which are
different from or additional to those available to the indemnifying  party or if
the interests of the indemnified party reasonably may be deemed to conflict with
the interests of the indemnifying  party,  the indemnified  party shall have the
right to  select a  separate  counsel  and to assume  such  legal  defenses  and
otherwise to  participate  in the defense of such action,  with the expenses and
fees of such separate counsel and other expenses  related to such  participation
to be reimbursed by the indemnifying party as incurred.

         (d) In order to provide for just and  equitable  contribution  to joint
liability under the Securities Act in any case in which either (i) any Holder of
Restricted  Stock  exercising  rights under this  Agreement,  or any controlling
person of any such Holder,  makes a claim for  indemnification  pursuant to this
Section 10 but it is judicially  determined (by the entry of a final judgment or
decree by a court of competent jurisdiction and the expiration of time to appeal
or the denial of the last right of appeal) that such  indemnification may not be
enforced in such case notwithstanding the fact that this Section 10 provides for
indemnification  in such case, or (ii) contribution under the Securities Act may
be  required  on the part of any such  selling  Holder  or any such  controlling
person in circumstances for which indemnification is provided under this Section
10; then, and in each such case, the Company and such Holder will  contribute to
the  aggregate  losses,  claims,  damages  or  liabilities  to which they may be
subject (after  contribution from others) in such proportion so that such Holder
is responsible  for the portion  represented  by the percentage  that the public
offering price of its  Restricted  Stock offered by the  registration  statement
bears  to  the  public  offering  price  of  all  securities   offered  by  such
registration  statement,  and the  Company  is  responsible  for  the  remaining
portion;  PROVIDED,  HOWEVER, that, in Section 11(f) of the Securities Act) will
be entitled to contribution from any person or entity who was not guilty of such
fraudulent misrepresentation.

         (e) Notwithstanding the foregoing, to the extent that the provisions on
indemnification and contribution contained in the underwriting agreement entered
into in connection  with the  underwritten  public offering are in conflict with
the foregoing  provisions,  the provisions in the  underwriting  agreement shall
control.

         (f) The  obligations  of the Company and Holders  under this Section 10
shall  survive  the  completion  of  any  offering  of  Restricted  Stock  in  a
registration  statement  under  Section  4,  5 or  13  of  this  Agreement,  and
otherwise.

         11.  CHANGES IN COMMON STOCK OR PREFERRED  STOCK.  If, and as often as,
there is any change in the Common Stock of Common Stock by way of a stock split,
stock  dividend,   combination  or   reclassification,   or  through  a  merger,
consolidation, reorganization or


                                        9

<PAGE>


recapitalization, or by any other means, appropriate adjustment shall be made in
the  provisions  hereof so that the rights and  privileges  granted hereby shall
continue with respect to the Common Stock as so changed.

         12. RULE 144 REPORTING. With a view to making available the benefits of
certain rules and regulations of the commission which may at any time permit the
sale of the Restricted  Stock to the public without  registration,  at all times
after  ninety  (90) days  after any  registration  statement  covering  a public
offering of securities of the Company under the Securities Act shall have become
effective, the Company agrees to:

         (a) make and keep  public  information  available,  as those  terms are
understood and defined in Rule 144 under the Securities Act;

         (b) file with the  Commission  in a timely manner all reports and other
documents required of the Company under the Securities Act and the Exchange Act;
and;

         (c) furnish to each Holder of Restricted Stock forthwith upon request a
written  statement  by the  Company  as to its  compliance  with  the  reporting
requirements  of such Rule 144 and of the Securities Act and the Exchange Act, a
copy of the most recent  annual or  quarterly  report of the  Company,  and such
other  reports  and  documents  so  filed  by the  Company  as such  Holder  may
reasonably  request  in  availing  itself  of  any  rule  or  regulation  of the
Commission   allowing  such  Holder  to  sell  any   Restricted   Stock  without
registration.

         13. TRANSFERABILITY OF REGISTRATION RIGHTS. The rights conferred herein
on the  Holders  of  Restricted  Stock  shall  only  inure to the  benefit  of a
transferee of Restricted Stock, (i) if the transfer was approved by the Board of
Directors of the Company (which approval shall not be unreasonably withheld) and
there is transferred to such transferee all of the Restricted Stock then held by
the  transferor  or (ii) if the  transferee  is a  transferee  permitted  in the
provision to Section 3; PROVIDED HOWEVER that no transferee shall receive rights
pursuant  to this  Agreement  unless it first  agrees in writing to abide by all
restrictions on the Holders hereunder.

         14.   REPRESENTATIONS  AND  WARRANTIES  OF  THE  COMPANY.  The  Company
represents and warrants to each Investor as follows:

         (a) The  execution,  delivery and  performance of this Agreement by the
Company have been duly authorized by all requisite corporate action and will not
violate  any  provision  of law,  any  order of any  court or  other  agency  of
government,  the  certificate of  incorporation  or bylaws of the Company or any
provision of any indenture,  agreement or other instrument to which it or any or
its  properties  or  assets is bound,  conflict  with,  result in a breach of or
constitute  (with due notice or lapse of time or both) a default  under any such
indenture, agreement or other instrument or result in the creation or imposition
of any lien,  charge or  encumbrance  of any nature  whatsoever  upon any of the
properties or assets of the Company.

         (b) This  Agreement as been duly  executed and delivered by the Company
and


                                       10

<PAGE>


constitutes the legal, valid and binding obligation of the Company,  enforceable
in accordance with its terms.

         15. MISCELLANEOUS.

         (a) BINDING  EFFECT.  All  covenants and  agreements  contained in this
Agreement  by or on behalf of any of the parties  hereto shall bind and inure to
the benefit of the  respective  successors  and  assigns of the  parties  hereto
(including without limitation  transferees of any Restricted Stock),  whether so
expressed or not.

         (b) NOTICES. All notices,  requests,  consents and other communications
hereunder  shall  be in  writing  and  shall  be sent by  nationally  recognized
overnight  courier  which  obtains a signed  receipt  upon  delivery,  mailed by
certified or registered mail,  return receipt  requested,  postage  prepaid,  or
telexed, in the case of non-U.S. residents,  addressed as follows: (i) if to the
Company or any other party hereto, at the address of such party set forth in the
Purchase  Agreement;  or (ii) if to any subsequent Holder of Common Stock, to it
at such address or  addresses as shall have  furnished in writing to the Company
(in the case of a Holder of  Restricted  Stock) or to the Holders of  Restricted
Stock (in the case of the Company) in  accordance  with the  provisions  of this
paragraph.

         (c) NO WAIVER:  CUMULATIVE REMEDIES. No failure or delay on the part of
any party to this Agreement in exercising any right,  power or remedy  hereunder
shall operate as a waiver thereof;  nor shall any single or partial  exercise of
any such right,  power or remedy preclude any other or further  exercise thereof
or the  exercise of any other  right,  power or remedy  hereunder.  The remedies
herein  provided are  cumulative  and not exclusive of any remedies  provided by
law.

         (d) AMENDMENTS, WAIVERS AND CONSENTS. This Agreement may not be amended
or modified,  and no provision hereof may be waived, without the written consent
of  the  Company  and  the  Holders  of at  least  sixty  percent  (60%)  of the
outstanding shares of Restricted Stock.

         (e)  TERMINATION.  The obligations of the Company to register shares of
Restricted  Stock under  Sections 4 and 5 shall  terminate  with  respect to any
Holder  at  such  time  as Rule  144 or  another  similar  exemption  under  the
Securities  Act is available for the sale of all such  Holder's  shares during a
three (3) month period without registration.

         (f)  SEVERABILITY.  If any provision of this Agreement shall be held to
be  illegal,   invalid  or   unenforceable,   such  illegality,   invalidity  or
unenforceability shall attach only to such provision and shall not in any manner
affect or render illegal,  invalid or unenforceable  any other provision of this
Agreement,  and this  Agreement  shall be  carried  out as if any such  illegal,
invalid or unenforceable provision were not contained herein.

         (g) GOVERNING LAW. This Agreement shall be governed by and construed in


                                       11

<PAGE>



accordance with the laws of the State of North  Carolina,  without giving effect
to the principles of the conflicts of laws thereof.

         (h) INJUNCTIVE  RELIEF.  The Company  recognizes that the rights of the
Investor under this Agreement are unique and,  accordingly,  the Investor shall,
in addition  to such other  remedies  as may be  available  to them at law or in
equity,  have the  right to  enforce  their  rights  hereunder  by  actions  for
injunctive relief and specific  performance to the extent permitted by law. This
Agreement is not  intended to limit or abridge any rights of the Investor  which
may exist apart from this Agreement.

         (i) MERGER PROVISION. This Agreement, along with the Purchase Agreement
of even date herewith,  including all exhibits and schedules thereto, constitute
the entire  agreement among the parties hereto  pertaining to the subject matter
hereof   and   supersede   all  prior   and   contemporaneous   agreements   and
understandings,  of any of the parties  hereto  concerning  the  subject  matter
hereof.

         (j)  COUNTERPARTS.  This  Agreement  may be  executed  in  two or  more
counterparts,  each of  which  shall be  deemed  an  original,  but all of which
together shall constitute one and the same instrument.


         [The remainder of this page left blank intentionally.]


                                       12

<PAGE>


         IN WITNESS WHEREOF, this Agreement has been executed as of the date and
year first above written.


                           BIOMAR INTERNATIONAL, INC.

                           By:  _____________________________________
                                T. Nelson Campbell
                                Chairman of the Board


                           PARACELSIAN, INC.

                           By:  _____________________________________
                                Dr. Thomas Tachovsky
                                President and Chief Executive Officer


                                       13



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