BIOSYS INC /CA/
10-Q/A, 1996-05-24
AGRICULTURAL CHEMICALS
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                This is an electronic filing of the exhibits filed on May 15,
                1996, pursuant to a Rule 201 - Temporary Hardship Exemption.  
                Papers copies of the exhibits were filed with the Securities 
                and Exchange Commission under the cover of Form SE on May 15, 
                1996.


                   QUARTERLY REPORT UNDER SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-Q
                                 --------------

                                      
            [ X ] Quarterly Report Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934
                  For the quarterly period ended March 31, 1996
                                      

                                       or

            [ ] Transition Report Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934
                 For the transition period from ______ to ______

                         Commission file number 0-19819


                                      
                                  biosys, inc.
                                      
             (Exact name of registrant as specified in its charter)

                 Delaware                                  94-2878645
         (State or other jurisdiction of                (I.R.S. Employer
         incorporation or organization)                 Identification No.)

        10150 Old Columbia Road, Columbia, Maryland             21046
        (Address of principal executive offices)             (Zip Code)

                                  410-381-3800
              (Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days. Yes XX No _____.


Indicate  the number of shares  outstanding  of each of the  issuers  classes of
common stock, as of the last practicable date: 7,487,298 shares of the Company's
Common Stock (par value $0.001) were outstanding as of April 30, 1996.



<PAGE>
                                  SIGNATURES



         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.



                                  biosys, inc.




Date:           May 15, 1996                   By:  /s/ Michael R.N. Thomas
      -----------------------------------           Michael R.N. Thomas
                                                    Vice President and
                                                    Chief Financial Officer
                                                    (Principal Financial and
                                                    Accounting Officer)




<PAGE>

                             
THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.65 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.

                                                As of April 1, 1996


VIA FACSIMILE AND HAND DELIVERY

Crop Genetics International Corporation
10150 Old Columbia Pike
Columbia, Maryland 21046
Attn: Dr. Edwin C. Quattlebaum, President

biosys, inc.
c/o Crop Genetics International Corporation
10150 Old Columbia Pike
Columbia, Maryland 21046
Attn: Dr. Edwin C. Quattlebaum, President

           Re: $3,400,000.00 Maryland Industrial Development Financing Authority
               Taxable Economic Development Revenue Bond Facility (Crop Genetics
               International Corporation Facility)


Gentlemen:


     Crop Genetics International Corporation and biosys, inc. (collectively, the
"OBLIGORS")  have requested  that The First  National Bank of Maryland  ("BANK")
agree to extend the time  period  for the  OBLIGORS  to perform  under and fully
satisfy  the terms and  conditions  of Section  8.2 (b) of that  certain  Second
Modification Agreement, dated October 2, 1995 ("SECOND MODIFICATION AGREEMENT"),
by and  among  the  OBLIGORS,  the  Maryland  Industrial  Development  Financing
Authority  ("MIDFA") and the BANK,  Section 2 of that certain Letter  Agreement,
dated as of November 30,  1995,  by and among the  OBLIGORS,  MIDFA and the BANK
("NOVEMBER  30  LETTER  AGREEMENT"),  Section  2  (a)  of  that  certain  Letter
Agreement,  dated as of December 5, 1995, by and among the  OBLIGORS,  MIDFA and
the BANK  ("DECEMBER  5 LETTER  AGREEMENT"),  Section 2 of that  certain  Letter
Agreement,  dated as of January 31, 1996, by and among the  OBLIGORS,  MIDFA and
the BANK ("JANUARY 31 LETTER  AGREEMENT"),  and Section 2 of that certain LETTER
AGREEMENT  dated as of March 15, 1996, by and among the OBLIGORS,  MIDFA and the
BANK  ("MARCH  15 LETTER  AGREEMENT").  The BANK has now had an  opportunity  to
review the request submitted by the OBLIGORS,  and in connection  therewith,  is
willing to agree as follows:
   
     1.  Definitions.  All  defined  terms  set  forth  or used  in the SECOND
MODIFICATION AGREEMENT,  the NOVEMBER 30 LETTER AGREEMENT, the DECEMBER 5 LETTER
AGREEMENT, the JANUARY 31 LETTER AGREEMENT, that certain Letter Agreement, dated
as of February 6, 1996, by and among the OBLIGORS, MIDFA and the BANK ("FEBRUARY
6 LETTER  AGREEMENT"),  and the MARCH 15 LETTER  AGREEMENT,  shall have the same
meaning in the event that such defined  terms are used in this Letter  Agreement
("LETTER AGREEMENT").  The term "BOND DOCUMENT", as used herein, shall mean and
include the BOND DOCUMENTS referenced in the SECOND MODIFICATION AGREEMENT , the
NOVEMBER 30 LETTER AGREEMENT,  the DECEMBER 5 LETTER  AGREEMENT,  the JANUARY 31
LETTER  AGREEMENT,  the  FEBRUARY  9 LETTER  AGREEMENT  , the  MARCH  15  LETTER
AGREEMENT,  this LETTER AGREEMENT, and all other documents evidencing,  securing
or otherwise documenting the above-referenced  credit facility.  The term "MIDFA
INSURANCE  AGREEMENT" as used herein, shall mean and include the MIDFA INSURANCE
AGREEMENT  referenced  in the SECOND  MODIFICATION  AGREEMENT,  as modified  and
extended  pursuant  to the  terms  and  conditions  of the  NOVEMBER  30  LETTER
AGREEMENT, the DECEMBER 5 LETTER AGREEMENT, the JANUARY 31 LETTER AGREEMENT, the
FEBRUARY  6 LETTER  AGREEMENT,  the MARCH 15 LETTER  AGREEMENT  and this  LETTER
AGREEMENT.

     2. Extension of Deadline;  No-Default.  Subject to the terms and conditions
set forth herein,  and provided no EVENT OF DEFAULT exists under any of the BOND
DOCUMENTS,  and further  provided  that this LETTER  AGREEMENT  is executed  and
delivered  by the  parties.  hereto on or before 5:00 p.m.  on Friday,  April 5,
1996, the BANK agrees that the time period for the OBLIGORS to perform under and
fully  satisfy  the  terms and  conditions  of  Section  8 .2 (b) of the  SECOND
MODIFICATION AGREEMENT, Section 2 of the NOVEMBER 30 LETTER AGREEMENT, Section 2
(a) of the  DECEMBER  5 LETTER  AGREEMENT,  Section 2 of the  JANUARY  31 LETTER
AGREEMENT  and Section 2 of the MARCH 15 LETTER  AGREEMENT  shall be extended to
and until the  earlier  of: (a) 5:00 p.m.  on May 1. 1996;  or (b) the date when
Imperial Bank establishes and documents  financial covenants for its outstanding
loan to biosys,  inc.  Furthermore,  the  OBLIGORS  shall not be  considered  in
default  under the BOND  DOCUMENTS  for having  failed to satisfy  the terms and
conditions of Section 8.2 (b) of the SECOND MODIFICATION AGREEMENT, Section 2 of
the  NOVEMBER  30  LETTER  AGREEMENT,  Section  2 (a) of the  DECEMBER  5 LETTER
AGREEMENT,  Section 2 of the  JANUARY 31 LETTER  AGREEMENT  and Section 2 of the
MARCH 15 LETTER AGREEMENT within the time periods prescribed therein.

     3.  Consent  and  Approval of MIDFA;  Acknowledgment  of  Liability;  Other
Agreements.  MIDFA  consents to and  approves the terms and  conditions  of this
LETTER AGREEMENT and acknowledges and agrees that the MIDFA INSURANCE  AGREEMENT
shall remain in place and in full force and effect,  notwithstanding  the BANK'S
execution of this LETTER AGREEMENT and the various agreements of the BANK as set
forth herein.  MIDFA further acknowledges and agrees that as of the date of this
LETTER AGREEMENT, MIDFA has received all notices that it was entitled to receive
from the BANK under and  pursuant  to the MIDFA  INSURANCE  AGREEMENT,  and that
MIDFA  does not have any  defense  to or set-off  or  counterclaim  against  its
liability  to  the  BANK  under  the  MIDFA  INSURANCE  AGREEMENT.   MIDFA  also
acknowledges  and agrees that pursuant to the terms and  conditions of the MIDFA
INSURANCE  AGREEMENT,  MIDFA maximum liability to the BANK thereunder  presently
equals and shall  hereafter  equal the  lesser  of: (a) the total  amount of the
INDEBTEDNESS  due and owing to the BANK  under the BOND  DOCUMENTS  from time to
time, or (b)  $3,000,000.00.  Except as specifically  modified herein, all other
terms, covenants and conditions set forth in the MIDFA INSURANCE AGREEMENT shall
remain unchanged, in full force and effect and are hereby ratified and confirmed
by MIDFA and the BANK in all respects.

     4. Other Terms and Conditions;  No Novation.  Other than the foregoing, all
other terms,  covenants and  conditions  set forth in the BOND  DOCUMENTS  shall
remain unchanged, in full force and effect and are hereby ratified, acknowledged
and  confirmed  by the  OBLIGORS,  MIDFA and the BANK in all  respects,  and the
OBLIGORS shall hereafter  strictly  comply with all of the terms,  covenants and
conditions set forth in the BOND DOCUMENTS  including,  without limitation,  the
payment  terms  set  forth  therein.  This  LETTER  AGREEMENT  shall not cause a
novation of any of the BOND DOCUMENTS, nor shall it extinguish, affect or impair
the  OBLIGORS'  or  MIDFA'S  respective  obligations  to the BANK under the BOND
DOCUMENTS.  In addition,  this LETTER  AGREEMENT  shall not  release,  affect or
impair the priority of any security  interests or liens held by the BANK against
any assets of the OBLIGORS including, without limitation, the COLLATERAL.
   
     5. Governing Law. The performance and construction of this LETTER AGREEMENT
and the other BOND  DOCUMENTS  S shall be  governed  by the laws of the State of
Maryland.
   
     6.  Amendment.  This  LETTER  AGREEMENT  may only be  altered,  modified or
amended by a writing executed by all of the parties hereto.

     7. Time.  Time is of the essence with respect to this LETTER  AGREEMENT and
the terms and conditions hereof.
    
     8. Tense Gender,  Defined Terms,  Captions,  Effective  Date,  Execution in
Counterparts and Via Facsimile:  Miscellaneous. As used herein, the plural shall
refer to and include the singular,  and the singular the plural,  and the use of
any gender shall  include and refer to any other  gender.  All defined terms are
capitalized  throughout this LETTER AGREEMENT.  All captions are for the purpose
of convenience  only.  This LETTER  AGREEMENT shall be executed and delivered by
the  parties  hereto on or before 5:00 p.m.  on Friday,  April 5. 1996,  and the
effective date of this LETTER  AGREEMENT  shall be Monday,  April 1, 1996.  This
LETTER  AGREEMENT  may  be  executed  and  delivered  in  counterparts.   Signed
counterparts  may be delivered  via  facsimile,  with all copies  delivered  via
facsimile to be deemed to have the same force and effect as if bearing  original
signatures.  As is  indicated  in the BOND  DOCUMENTS,  all costs,  expenses and
attorneys'  fees incurred or hereafter  incurred by the BANK in connection  with
the  transactions  referenced  herein or otherwise in  connection  with the BOND
DOCUMENTS shall be the  responsibility  of the OBLIGORS and shall be paid for by
the OBLIGORS to the BANK in accordance  with the terms and conditions of Section
21 of the FIRST  MODIFICATION  AGREEMENT  referenced in the SECOND  MODIFICATION
AGREEMENT.

     9. Waiver of Jury Trial.  The  OBLIGORS,  MIDFA and the BANK agree that any
suit, action or proceeding, whether claim or counterclaim, brought or instituted
by or against any of them,  or any of their  successors  or assigns,  on or with
respect to this LETTER AGREEMENT,  or any other BOND DOCUMENTS,  or which in any
way relates, directly or indirectly, to the respective obligations of any of the
parties hereto under any of the BOND  DOCUMENTS,  or the dealings of the parties
with  respect  thereto,  shall be tried  only by a court and not by a jury.  THE
OBLIGORS, MIDFA AND THE BANK EXPRESSLY WAIVE THE RIGHT TO A TRIAL BY JURY IN ANY
SUCH SUIT, ACTION OR PROCEEDING.  The parties hereto  acknowledge and agree that
this  provision is a material  aspect of the  agreement  between the parties and
that the BANK would not enter into this LETTER  AGREEMENT if this provision,  or
any other provision of this LETTER AGREEMENT were not contained herein.

     If the terms and conditions set forth above are acceptable to the OBLIGORS,
the  OBLIGORS  should  execute this LETTER  AGREEMENT in the spaces  designated,
should have their  signatures  appropriately  attested to and notarized,  should
cause this LETTER  AGREEMENT  to be executed  by MIDFA,  and also cause  MIDFA's
signature to be appropriately  attested to and notarized,  and should return the
fully executed AGREEMENT,  without modification,  to my attention,  on or before
5:00 p.m. on Friday,  April 5, 1996.  After 5:00 p.m. on Friday,  April 5, 1996,
the offer of the BANK as set forth herein  shall be withdrawn  and of no further
force or  effect,  unless  before  such time,  this  LETTER  AGREEMENT  has been
executed by the  OBLIGORS and MIDFA and returned to my attention as provided for
above.

Very truly yours,

THE FIRST NATIONAL BANK OF MARYLAND,
a national banking association

By:  W. Blake Hampson  (SEAL)
      Vice President
<PAGE>


AGREED AND CONSENTED TO:

WITNESS/ATTEST:                             OBLIGORS

                                            CROP GENETICS INTERNATIONAL
                                            CORPORATION,
                                            A Delaware Corporation

Sandra Soroka                               By:      Michael R. N. Thomas
                                            Title:   Chief Financial Officer
                                            Date:    April 4, 1996



WITNESS/ATTEST:                             BIOSYS, INC.,
                                            A Delaware Corporation

Sandra Soroka                               By:      Michael R. N. Thomas
                                            Title:   Chief Financial Officer
                                            Date:    April 4, 1996

<PAGE>



STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:'

     I HEREBY  CERTIFY,  that on this 5th day of April,  1996,  before  me,  the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Michael R. N. Thomas, who acknowledged himself to be the Chief Financial Officer
of BIOSYS, INC., a Delaware  corporation,  and who further acknowledged that he,
as such  Chief  Financial  Officer,  being  authorized  so to do,  executed  the
foregoing  instrument for the purposes therein  contained by signing the name of
BIOSYS, INC., by himself as Chief Financial Officer.

      IN WITNESS MY Hand and Notarial Seal.
                                            Sandra Soroka   (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
June 24, 1998


STATE OF ________________CITY/COUNTY OF ________________TO WIT:'
   
     I HEREBY CERTIFY,  that on this ______ day of __________,  1996, before me,
the  undersigned,  a Notary  Public of the  jurisdiction  aforesaid,  personally
appeared   _____________,   who   acknowledged   himself/herself   to   be   the
________________of  MARYLAND INDUSTRIAL  DEVELOPMENT FINANCING AUTHORITY, a body
politic  and  corporate,  and who  further  acknowledged  that  he/she,  as such
________________,  being authorized so to do, executed the foregoing  instrument
for the purposes  therein  contained by signing the name of MARYLAND  INDUSTRIAL
DEVELOPMENT  FINANCING  AUTHORITY,  by  himself/herself  as MARYLAND  INDUSTRIAL
DEVELOPMENT FINANCING AUTHORITY.
   
     IN WITNESS MY Hand and Notarial Seal.
                                            ________________  (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
___________________

<PAGE>


AGREED AND CONSENTED TO:

WITNESS/ATTEST:                     OBLIGORS

                                    CROP GENETICS INTERNATIONAL
                                    CORPORATION,
                                    A Delaware Corporation

Sandra Soroka                       By:   Edwin C. Quattlebaum
                                 Title:   President and Chief Executive Officer
                                  Date:   April 12, 1996



WITNESS/ATTEST:                     BIOSYS, INC.,
                                    A Delaware Corporation

Sandra Soroka                       By:   Edwin C. Quattlebaum
                                 Title:   President and Chief Executive Officer
                                  Date:   April 12, 1996

<PAGE>
 

WITNESS/ATTEST.                             MIDFA:

                                            MARYLAND INDUSTRIAL DEVELOPMENT
                                            FINANCING AUTHORITY,
                                            A Body Politic and Corporate and
                                            a Public instrumentality of the
                                            State of Maryland

                                            By:                          (SEAL)
                                            Name:
                                            Title:

                                            Date:



                                                  ACKNOWLEDGMENTS

STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:'

     I HEREBY  CERTIFY,  that on this 12th day of April,  1996,  before  me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Edwin Quattlebaum, who acknowledged himself to be the President of CROP GENETICS
INTERNATIONAL CORPORATION, a Delaware corporation,  and who further acknowledged
that he, as such  President,  being  authorized so to do, executed the foregoing
instrument  for the  purposes  therein  contained  by  signing  the name of CROP
GENETICS INTERNATIONAL CORPORATION, by himself as President.

         IN WITNESS MY Hand and Notarial Seal.
                                            Sandra Soroka   (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
June 24, 1998


<PAGE>

STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:'

     I HEREBY  CERTIFY,  that on this 12th day of April,  1996,  before  me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Edwin Quattlebaum, who acknowledged himself to be the President of CROP GENETICS
INTERNATIONAL CORPORATION, a Delaware corporation,  and who further acknowledged
that he, as such  President,  being  authorized so to do, executed the foregoing
instrument  for the  purposes  therein  contained  by  signing  the name of CROP
GENETICS INTERNATIONAL CORPORATION, by himself as President.
      
     IN WITNESS MY Hand and Notarial Seal.
                                            Sandra Soroka   (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
June 24, 1998


STATE OF ________________CITY/COUNTY OF ________________TO WIT:'

     I HEREBY CERTIFY,  that on this ______ day of __________,  1996, before me,
the  undersigned,  a Notary  Public of the  jurisdiction  aforesaid,  personally
appeared   _____________,   who   acknowledged   himself/herself   to   be   the
________________of  MARYLAND INDUSTRIAL  DEVELOPMENT FINANCING AUTHORITY, a body
politic  and  corporate,  and who  further  acknowledged  that  he/she,  as such
________________,  being authorized so to do, executed the foregoing  instrument
for the purposes  therein  contained by signing the name of MARYLAND  INDUSTRIAL
DEVELOPMENT  FINANCING  AUTHORITY,  by  himself/herself  as MARYLAND  INDUSTRIAL
DEVELOPMENT FINANCING AUTHORITY.

         IN WITNESS MY Hand and Notarial Seal.
                                            ________________  (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
___________________


<PAGE>

WITNESS/ATTEST-.                            MIDFA:

                                            MARYLAND INDUSTRIAL DEVELOPMENT
                                            FINANCING AUTHORITY,
                                            A Body Politic and Corporate and a
                                            Public instrumentality of the State
                                            of Maryland

                                            By:        Stephen J. Lynch   (SEAL)
                                            Name:      Stephen J. Lynch
                                            Title:     Assistant Secretary of
                                                       Financing Programs

                                            Date:      April 4, 1996



                                 ACKNOWLEDGMENTS

STATE OF ________________ CITY/COUNTY OF ________________ TO WIT:

     I HEREBY  CERTIFY,  that on this ___ day of  ______,  1996,  before me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
________________,  who acknowledged  himself to be the  ________________ of CROP
GENETICS  INTERNATIONAL  CORPORATION,  a Delaware  corporation,  and who further
acknowledged  that he,  as such  ________________,  being  authorized  so to do,
executed the foregoing  instrument for the purposes therein contained by signing
the name of CROP GENETICS INTERNATIONAL CORPORATION, by himself as President.
        
     IN WITNESS MY Hand and Notarial Seal.
                                            ________________ (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
____________________


<PAGE>

STATE OF _______________ CITY/COUNTY OF _______________ TO WIT:'

     I HEREBY  CERTIFY,  that on this ___ day of _______,  1996,  before me, the
undersigned,   a  Notary  Public  of  the  jurisdiction  aforesaid,  personally
____________, who acknowledged himself to be the __________ of BIOSYS, Inc., a
Delaware  corporation,  and who further acknowledged that he, as such President
and Chief Executive  Officer,  being authorized so to do, executed the foregoing
instrument  for the  purposes  therein  contained by signing the name of BIOSYS,
Inc., by himself as President.

     IN WITNESS MY Hand and Notarial Seal.
                                            ________________ (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
____________________



STATE OF MARYLAND CITY/COUNTY OF BALTIMORE TO WIT:'

     I HEREBY  CERTIFY,  that on this 4th day of April,  1996,  before  me,  the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Stephen J. Lynch, who acknowledged himself/herself to be the Assistant Secretary
of  Financing  Programs  of  the  MARYLAND  INDUSTRIAL   DEVELOPMENT   FINANCING
AUTHORITY,  a body  politic and  corporate,  and who further  acknowledged  that
he/she, as such Assistant Secretary of Financing  Programs,  being authorized so
to do, executed the foregoing  instrument for the purposes therein  contained by
signing the name of the MARYLAND INDUSTRIAL DEVELOPMENT FINANCING AUTHORITY,  by
himself/herself as Assistant Secretary of Financing Programs.

         IN WITNESS MY Hand and Notarial Seal.
                                            Jane B. Sibez  (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
November 1, 1980

                              
<PAGE>

TEXT>
THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.66 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.

                               FIRST AMENDMENT TO

                        CONTRACT MANUFACTURING AGREEMENT

     This  First   Amendment  to  Contract   Manufacturing   Agreement   ("First
Amendment")  is made this  16th day of  April,  1996 by and  between  BIOSYS,  a
Delaware corporation ("biosys"), and ARCHER-DANIELS-MIDLAND  COMPANY, a Delaware
corporation ("ADM").
                              W I T N E S S E T H:

     WHEREAS,  biosys and ADM are parties to that certain Contract Manufacturing
Agreement dated December 2, 1993 (the "Agreement"); and
        
     WHEREAS, biosys and ADM desire to amend the Agreement.

     NOW,  THEREFORE,  in  consideration  of the premises  and mutual  covenants
contained herein, it is agreed as follows:

          1. The Agreement is amended,  effective March 18, 1996, as follows:

               a)   Section 3.02 is deleted and, in lieu thereof,  the following
                    is inserted as a new Section  3.02: 

                    Fermentation  Capacity.  The biosys  Facility  shall have an
                    initial  capacity of five (5) nominal  22,000 gallon (16,000
                    W/V) main  fermenters,  five (5) nominal  2,000  gallon seed
                    fermenters,  and  four (4)  nominal  50  gallon  propagation
                    fermenters.   The  biosys  fermenters  shall  be  designated
                    jointly by the parties.

               b)   In Section  4.02,  second line,  the words "or Omega 3 Fatty
                    Acid" are deleted.

               c)   Section  6.01 is  amended  by  deleting  the  fees  for 1996
                    through 2006 and beyond and, in lieu thereof,  inserting the
                    following fees for the corresponding periods:
                                               Year                  Annual Fee
                                               1996               $2.825 million
                                               1997               $3.125 million
                                               1998               $3.750 million
                                               1999               $4.375 million
                                               2000               $4.375 million
                                               2001               $4.375 million
                                               2002               $4.675 million
                                               2003               $4.675 million
                                               2003               $4.675 million
                                               2004               $4.675 million
                                               2005               $5.0   million
                                               2006 and beyond    $4.065 million

               d)   Section 7.02 is deleted and, in lieu thereof,  the following
                    is inserted as a new Section 7.02:

                    biosys  agrees that ADM shall be the  exclusive  producer of
                    nematodes and their  equivalent  products for biosys through
                    1994,  and for the  North and South  American  sales  beyond
                    1994. In the event sales of biosys' own Products  during the
                    period  January  through  June of any year would  require an
                    expansion of the biosys  Facility  beyond that  described in
                    Section  3.02,  ADM shall use its best  efforts to make such
                    expansion and to complete the same within twelve (12) months
                    after the decision is made that such  expansion is required,
                    unless the existing  22,000  gallon  nominal  fermenters  in
                    BioChem II are  available  for and can be used to accomplish
                    the  expansion,  in which case it shall be completed  within
                    six (6)  months  of the  decision  to make  such  expansion.
                    Except at ADM's option, this expanded capacity shall be used
                    exclusively  for the  production  of biosys'  own  Products.
                    biosys  shall  pay to  ADM,  on a  monthly  basis  beginning
                    start-up  of the  expansion  equipment,  1/12 of annual  fee
                    equal to 40 percent of the expansion project cost.
 
          2.   Except as  specifically  modified  herein,  all provisions of the
               Agreement   shall  remain  in  full  force  and  effect   without
               alteration.  IN WITNESS WHEREOF, the parties hereto have executed
               this First Amendment on the date first written above.


BIOSYS                                 ARCHER-DANIELS-MIDLAND COMPANY

By: Edwin C. Quattlebaum               By:
      Its: Chief Executive Officer     Its: President - ADM BioProducts Division

<PAGE>

THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.67 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.


                               SUB-LEASE AGREEMENT




                                     BETWEEN



                                  BIOSYS, INC.


                           CROP GENETICS INTERNATIONAL
                                   CORPORATION

                                       AND

                                GENE LOGIC, INC.





                                DATED MAY 2, 1996


<PAGE>


                               SUB-LEASE AGREEMENT


      This  Sub-Lease  Agreement is executed  this 2nd day of May,  1996, by and
between Gene Logic, Inc. (referred to as "Sub-Tenant"),  a corporation organized
and  conducting  business  under the laws of the  State of  Delaware  and,  Crop
Genetics  International  Corporation  ("Crop"),  and  biosys,  Inc.  ("biosys"),
corporations  organized and  conducting  business under the laws of the State of
Delaware,  (collectively  referred  to as  "Sub-Landlord"),  and  registered  to
conduct business in the State of Maryland.


                                    RECITALS

     I. WHEREAS,  M.O.R.  XVIII Associates  limited  Partnership,  a limited
partnership  formed  under the laws of the  State of  Maryland  (referred  to as
"Landlord") is the owner of a building  containing  approximately  75,500 square
feet (the  "Building")  constructed on land leased by Landlord and designated as
Parcel  M-2  (the  "Land")  on  the  Plat  entitled  "Parcels  M-2  and  M-3,  A
Resubdivision  of Parcel M-1 Plat No.  5194",  which plat is recorded  among the
Land  Records of Howard  County,  Maryland as Plat No. 5693.  The Land  contains
approximately  11 acres,  is  located at 10150 Old  Columbia  Road in the Rivers
Corporate  Park (the "Park") in Columbia,  Howard  County,  Maryland  21044 (the
"County"),  and is more  particularly  shown on Exhibit A,  attached  hereto and
incorporated  by reference  herein and accepted by the  parties.  The Land,  the
Building,   the  easements  and  rights  appurtenant  thereto  (including  those
established by certain declarations of covenants recorded prior hereto among the
Land  Records  of the  County),  and the  sidewalks,  areaways,  parking  areas,
driveways, loading areas, gardens and lawns surrounding the building and located
on the Land are collectively referred to as the "Leased Premises; "

     II. WHEREAS,  Sub-Landlord  occupies the Leased Premises  pursuant to a
lease  between Crop and Landlord  dated October 1, 1992 (the "Prime  Lease"),  a
copy of which is  attached  hereto as Exhibit B and  incorporated  by  reference
herein and  accepted by the parties.  biosys has fully  assumed with Crop all of
Crop's obligations pursuant to the Prime Lease;

     III. WHEREAS, during its leasehold of the Leased Premises, Sub-Landlord
invested in leasehold  improvements and equipment (which, to the extent the same
are personal property,  are herein referred to as the "Leasehold  Improvements")
which  together  with other assets were  financed by a loan  (referred to as the
"Loan") in the principal  amount of Three Million Four Hundred  Thousand Dollars
($3,400,000.00),  evidenced  by a Promissory  Note  (referred to as the "Note"),
dated December 7, 1994 payable to the First National Bank of Maryland  (referred
to as the  "Bank")  from  funds  raised  by the sale of  bonds  by the  Maryland
Industrial Development Finance Authority (referred to as "MIDFA");

     IV. WHEREAS,  the Note is secured by: 1) a Security Agreement  (referred to
as the "Security Agreement") dated December 7, 1994, by and between Sub-Landlord
and MIDFA,  granting to MIDFA a security  interest  in certain of the  Leasehold
Improvement;  and, ii) two Collateral  Assignments  of Lease,  dated December 7,
1994,  by  Sub-Landlord  to and for the benefit of MIDFA  assigning to MIDFA the
Sub-Landlord's  leasehold  interest in the Leased  Premises  (both  collectively
referred to as the "Lease Assignments");

     V. WHEREAS,  Sub-Landlord,  Bank and MIDFA entered into a  Modification
Agreement, Guaranty Agreement and Post Closing Agreement in respect to the Loan,
Note,  Security  Agreement and Lease  Assignments dated May 26, 1995, (all three
collectively  referred  to as the  "Modification  Documents").  Pursuant  to the
Modification  Documents,  Sub-Landlord has executed an Assignment of Interest in
this Sub-Lease to the Bank and MIDFA,  which is attached hereto and incorporated
by  reference  herein as Exhibit C and  accepted by the Parties  (all  documents
evidencing,   securing  or  governing   the  Loan,   the  Note,   the  Leasehold
Improvements,  the Modification Documents,  and the rights of the Bank and MIDFA
are referred to collectively as the "Security Documents"); and,

     VI.  WHEREAS,  Sub-Tenant  desires to  sub-lease  from  Sub-Landlord  a
portion of the Leased Premises (referred to as the "Sub-Leased Premises"), shown
on Exhibit D which is attached hereto and  incorporated by reference  herein and
accepted by the parties, totaling 9,600 net rentable square feet for a period of
time provided in Section 1 below (referred to as the "Term").

     NOW THEREFORE, in consideration of these recitals and the consideration
set forth  herein,  Sub-Landlord  does hereby  sub-lease  unto  Sub-Tenant,  and
Sub-Tenant does hereby lease from Sub-Landlord the Sub-Leased  Premises pursuant
to the following terms and conditions.

1.   Term and Extension.  The Term is five (5) years beginning on the 1st day of
May,  1996 (the "Term  Commencement  Date") and ending on the 30th day of April,
2001 (the "Initial Term Expiration  Date").  Sub-Tenant  shall have the right to
extend the Term of this lease  thereafter for succeeding  additional  periods of
one (1) year each (each an "  Extension  Term"),  through  the Term of the Prime
Lease, based on then current market rental rates for the Sub-Leased Premises, by
giving  Sub-Landlord  nine (9) months notice prior to the end of the Term or any
Extension Term hereof ("Notice").
   
     Sub-Landlord  and Sub-Tenant  shall attempt to reach agreement on the then
current fair market rental rates for the Sub-Leased  Premises during a period of
Ninety (90) days after  SubLandlord  receives  the Notice.  If they agree within
such  Ninety  (90) day  period,  they will amend this lease to state the current
market rent for the  Extension  Term. If they are unable to agree on the initial
monthly rent and rental increases for the Extension Term within such Ninety (90)
day period,  the  Sub-Lease  shall expire at the end of the original Term or any
Extension thereof then in effect.

2.   Rent, Space and Payment.

     a.  Sub-Leased  Premises  and Base  Rent,  Sub-Tenant  shall  make  monthly
payments  for the use of the  Sub-Leased  Premises  (referred to as the "Monthly
Payments ") at the rate of Twenty-One  Dollars and Fifty-Five Cents ($21.55) per
net rentable square foot per annum, full service,  which shall be comprised of a
Base Rent of $14.75  ("Base  Rent") per net  rentable  square  foot,  subject to
increase from time to time as provided in 2.b. below, and an initial rental year
estimate of  operating  costs of $6.80 per net  rentable  square foot  ("Initial
Estimated  Operating  Costs"),  which  estimate  shall be subject to increase as
provided  in 2.c.  below.  The  Sub-Leased  Premises,  for all  purposes of this
Sub-Lease,  shall be deemed by each of the Parties  hereto as 9,600 net rentable
square feet  measured by and agreed to by the  Parties,  resulting in an initial
Monthly Payment of Seventeen Thousand Two Hundred Forty Dollars ($17,240.00) for
the first rental year hereunder.  Monthly Payments shall be prorated for partial
months; and shall be payable in advance monthly by the first day of each month.

     b. Annual Increase in Base Rent.  Commencing on May 1, 1998, and continuing
on the anniversary of the Term  Commencement  Date during each year of the Term,
the Base Rent shall increase annually by Three Percent (3 %).

     c. Payment of Operating  Costs.  For each Operating  Year (defined  below),
Sub-Tenant   shall  pay  to   Sub-Landlord,   in  the  manner  provided  herein,
Sub-Tenant's  Proportionate  Share  (defined  below) of Actual  Operating  Costs
(defined below),  which  Sub-Tenant's  Proportionate  Share shall be computed by
multiplying  the Actual  Operating  Costs for the Operating Year by Sub-Tenant's
Proportionate  Share  (defined as the total square feet of  Sub-Leased  Premises
divided by 75,500  square  feet of Leased  Premises);  provided,  however,  that
Sub-Tenant's Proportionate Share of Actual Operating Costs shall be prorated for
partial Operating Years in the Term, if any.

     (1) Actual Costs.  Within 120 days following the end of the first Operating
Year, SubLandlord shall provide Sub-Tenant a statement of Actual Operating Costs
incurred during the first Operating Year and  Sub-Tenant's  Proportionate  Share
thereof.  Within  30  days  of its  receipt  of said  statement  of said  Actual
Operating  Costs,  Sub-Tenant will pay to Sub-Landlord its  Proportionate  Share
thereof,  less a credit of the total Initial  Estimated  Operating Costs for the
first  Operating Year (computed at the rate of $6.80 for each square foot of Sub
Leased Premises).

     (2) Estimated  Payments.  During each Operating  Year or partial  Operating
Year following the first  Operating Year in the Term, in addition to the Monthly
Payment , Sub-Tenant  will pay to Sub-Landlord on the first day of each month an
amount  equal  to  1/12  of  the  product  of  SubTenant's  Proportionate  Share
multiplied by Sub-Landlord's Estimated Increased Operating Costs (defined below)
for such Operating  Year  ("Estimated  Increased  Operating  Costs").  Estimated
Increased  Operating  Costs for any Operating Year is defined as  Sub-Landlord's
reasonable  estimate of Actual  Operating Costs for such Operating Year less the
Base Operating  Costs (which is defined to be the total  Operating Costs for the
first Operating Year of the Sub-Lease). Estimates prepared by Sub-Landlord shall
be delivered to Sub-Tenant  Thirty (30) Days prior to the  commencement  of each
Operating  Year. If,  however,  Sub-Landlord  fails to furnish any such estimate
prior to the commencement of an Operating Year, then Sub-Tenant will continue to
make payments of Estimated Increased Operating Costs it was making at the end of
the prior  Operating  Year, if any.  Within Thirty days  following  Sub-Tenant's
receipt  of  Sub-Landlord's   revised  Estimated   Increased   Operating  Costs,
Sub-Tenant will pay to  Sub-Landlord  for each month which has elapsed since the
beginning of the applicable  Operating  Year, the difference  between the amount
payable  based upon the  revised  Estimated  Increased  Operating  Costs and the
amount paid to date by Sub-Tenant.

     (3) Annual  Settlement.  Within  120 days  after the end of each  Operating
Year,  SubLandlord  shall deliver to Sub-Tenant a statement of Actual  Operating
Costs and of amounts  payable  under this  Section 2c for such  Operating  Year,
prepared and certified by Sub-Landlord.  If such statement shows an amount owing
by  Sub-Tenant  that is less  than the  estimated  payments  previously  made by
Sub-Tenant for such Operating Year, the excess at the option of Sub-Tenant shall
be refunded by  Sub-Landlord  within  Thirty  (30) days  following  Sub-Tenant's
election or credited against the next payment of rent;  however, if the Term has
ended,  Sub-Landlord  shall refund the excess to  Sub-Tenant.  If such statement
shows an amount owing by  Sub-Tenant  that is more than the  estimated  payments
previously made by Sub-Tenant for such Operating  Year,  Sub-Tenant will pay the
deficiency  to  landlord  within  Thirty  (30) days after the  delivery  of such
statement.

     (4)  Verification.   Actual  Operating  Costs  shall  be  calculated  using
generally accepted accounting principles  consistently applied and the statement
or invoice  therefor  certified  by  SubLandlord.  Sub-Tenant  will be  entitled
annually  during the Term hereof and upon  reasonable  notice to Sub-Landlord to
audit and verify, at its sole cost and expense,  the operations of the SubLeased
Premises  and  Building  and the related  books and records of  Sub-Landlord  to
assure that the Operating Costs reported by Sub-Landlord are in keeping with the
provisions of this SubLease. In the event of any error,  Sub-Landlord shall make
a  correcting  payment  in full to the  Sub-Tenant  within  30  days  after  the
determination of the amount of such error.


     For purposes of this Sub-Lease, the term "Actual Operating Costs" means all
reasonable   costs  of  maintenance  of  the  Building,   wages,   salaries  and
compensation  of employees,  janitorial,  maintenance,  guard and other services
provided for the Building,  power,  water,  waste disposal,  and other utilities
provided to the  Building,  materials,  supplies  and repairs  provided  for the
Building and insurance for the Building.

     Actual Operating Costs shall not include:

     (1)  Wages,  salaries,  fees, and fringe benefits paid to administrative or
          executive  personnel  or  officers  or  partners  of  Sub-Landlord  or
          Landlord   unless   employed  at  competitive   rates  as  independent
          contractors;
   
     (2)  Any charge for  depreciation  of the  Building  or  equipment  and any
          interest or other financing charge;

     (3)  Any charge for  Sub-Landlord's  or  Landlord's  income  taxes,  excess
          profit  taxes,   franchise  taxes,  or  similar  taxes  on  landlord's
          business;

     (4)  All costs relating to activities for the solicitation and execution of
          leases of space in the Building and leasing costs, including brokerage
          commissions,   legal  fees,   vacancy  costs,  and   refurbishment  or
          improvement  expenses  relating to the  solicitation  and execution of
          leases;
        
     (5)  All costs for which  Sub-Tenant or any other tenant in the Building is
          being  charged  other than  pursuant  to this  Actual  Operating  Cost
          clause; 

     (6)  The cost of any repair made by Sub-Landlord or Landlord because of the
          total or partial  destruction of the building or the condemnation of a
          portion of the Building;
        
     (7)  The cost of any items for which Sub-Landlord or Landlord is reimbursed
          by insurance or otherwise compensated by parties other than tenants of
          the building pursuant to clauses similar to this section;

     (8)  The cost of any  additions  or capital  improvements  to the  Building
          subsequent to the date of original construction;
        
     (9)  The   cost   of  any   repairs,   alterations,   additions,   changes,
          replacements, and other items that under generally accepted accounting
          principles  are properly  classified  as capital  expenditures  to the
          extent  they  upgrade or improve  the  Building  as opposed to replace
          existing items that have worn out;
         
     (10) Any  operating  expense  representing  an  amount  paid  to a  related
          corporation,  entity,  or person  that is in excess of the amount that
          would be paid in the absence of such relationship;

     (11) The cost of tools and equipment used initially in the  construction of
          the Building;

     (12) The cost of any work or service performed for or facilities  furnished
          to any tenant of the Building to a greater  extent or in a manner more
          favorable  to such  tenant than that  performed  for or  furnished  to
          tenant;

     (13) The  cost of  alterations  of space in the  Building  leased  to other
          tenants; and
       
     (14) The cost of overtime or other  expense to  Sub-Landlord  in curing its
          defaults or performing work expressly provided in this Sub-Lease to be
          borne at landlord's expense;

     (15) any and all loan  payments,  principal or interest,  or ground  lease,
          equipment lease, tenant improvement costs or similar payments;

     (16) any and all collection costs, including legal fees and bad debt losses
          or reserves;
       
     (17) any otherwise  permissible  fees or costs,  to the extent in excess of
          prevailing and competitive rates; and

     (18) any documentary transfer taxes imposed in connection with the lease or
          any other lease.
       
     For purposes of this Section,  "Operating  Year" means each one year period
beginning  on May 1 and ending on April 30 and the term "Base  Operating  Costs"
means the Actual  Operating  Costs for the first  Operating  Year  following the
Commencement Date.

d.   Payment and  Proration  of Rent.  All  payments of Base Rent due  hereunder
shall be paid to Sub-Landlord by the first day of each month, and other payments
due hereunder shall be paid within thirty (30) days of  Sub-Tenant's  receipt of
notice  of such from  Sub-Landlord,  at the  address  designated  for  notice to
Sub-Landlord  herein, or as otherwise  designated by Sub-Landlord.  Payments for
Rent shall be adjusted for any period of less than a full month, calculated from
the beginning of said month. Sub-Tenant shall pay, a late charge based on a rate
of eighteen percent (18%) per annum on any amount in arrears.
        
e.   Option to Lease Additional Space). Sub-Tenant shall have an Option to lease
the  additional  laboratory and office space  ("Additional  Space") set forth in
Exhibit E hereto,  at the then current fair market rent for the Additional Space
determined as of the time it executes said option; provided that such Additional
Space will not be available to Sub-Tenant  for  occupancy  prior to May 1, 1998,
unless  earlier  provided  for by  Sub-Landlord,  in its sole  and  unreviewable
discretion,  and further  provided,  that such Option  must be  exercised  on or
before August 1, 1997.

     Sub-Landlord  and  Sub-Tenant  shall  attempt  to reach  agreement  on the
current  fair market  rental rates for the  Additional  Space during a period of
Ninety (90) days after  Sub-Landlord  receives the Notice.  If they agree within
such  Ninety  (90) day  period,  they will amend this lease to state the current
market rent for the  Extension  Term. If they are unable to agree on the initial
monthly rent and rental increases for the Extension Term within such Ninety (90)
day  period,  then  Sub-Tenant's  option to lease said  Additional  Space  shall
expire,   unless  further  extended  by  the  Sub-Landlord,   in  its  sole  and
unreviewable discretion.

f.   Security  Deposit.  Sub-Tenant  shall  pay  as  security  deposit  for  its
occupancy  of the  SubLeased  Premises  the sum of  Forty-Seven  Thousand  Three
Hundred Eighty-Seven  Dollars and 49 Cents ($47,387.49),  representing three (3)
months rent; provided, that Sub-Landlord agrees to deposit said security deposit
into an interest  bearing  account for the  benefit of  Sub-Tenant,  and further
provided,  that  one-third  (1/3) of the amount so deposited will be returned to
Sub-Tenant,  along with any interest  accrued  thereon,  on May 1, 1997, that an
additional  one-third  (1/3) of the  amount so  deposited  will be  returned  to
Sub-Tenant,  along with any interest accrued  thereon,  on May 1, 1998, with the
balance of the Security  Deposit to remain on deposit for  remainder of the Term
or  Extension  Term hereof,  except that  Sub-Tenant  shall be tendered  accrued
interest on the remaining  Security Deposit  thereafter on each anniversary date
thereof.  Upon  termination  of the  Sub-Lease,  the security  deposit  shall be
returned to Sub-Tenant,  with all accrued interest thereon, following deductions
for repairs and damage for which  Sub-Tenant is  responsible  under the terms of
this Sub-Lease.

3.    Condition and Use of Sub-Leased Premises.

a.   Inspection  of  Sub-Leased  Premises.   Seventy-Two  (72)  hours  prior  to
Sub-Tenant's  occupancy of the Sub-Leased Premises,  Sub-Landlord and Sub-Tenant
shall inspect the SubLeased  Premises for purposes of reviewing the condition of
the Sub-Leased Premises and identifying any of Sub-Landlord's  property, if any,
which is to be removed therefrom prior to Sub-Tenant's occupancy.

b.   Acceptance of Sub-Leased Premises. Except as otherwise provide herein, Sub-
Tenant shall accept the  Sub-Leased  Premises "As Is" condition for the purposes
for which Sub-Tenant intends to use and occupy the Sub-Leased Premises.

c. Use. Sub-Tenant shall not use or permit the use of any portion of the Sub-
Leased Premises for any purpose other than stated in Exhibit F hereto.

d.  Requirements  of Law.  Sub-Tenant  shall,  at the sole cost and  expense  of
Sub-Tenant,  observe  and comply  with all laws,  requirements,  rules,  orders,
ordinances and regulations of any governmental,  quasi-governmental entity or of
the local Board of Fire  Underwriters  applicable to its  particular  use of any
portion of the Sub-Leased Premises.

e.  Condition of premises.  Sub-Tenant  shall at all times during the Lease term
take good care of and keep the Sub-Leased  Premises in good order and condition.
Sub-Tenant shall not commit or suffer any waste to or of the Sub-Leased Premises
and will assign responsibility for all maintenance and repair, regardless of the
nature, pertaining to the Sub-Leased Premises.  SubLandlord shall be responsible
for  maintaining  the  improvements,  fixtures,  and  equipment  of the Building
(including,  but not limited to, the walls,  windows,  doors,  pipes , plumbing,
water  and  sewer  connections,  heating  and  air  conditioning  equipment  and
machinery, and electrical works of the Building) in good order and condition.

f.   Sub-Tenant's Failure to Perform. In the event that Sub-Tenant shall fail, a
(15) days written notice from Sub-Landlord,  to keep the Sub-Leased  Premises in
the state of condition  and repair  required by this  Sub-Lease,  to do any act;
make any payment; this lease, Sub-Landlord may (at its option, but without being
required to do so)  immediately,  or at any time  thereafter and without notice,
perform the same for the account of Sub-Tenant  (including,  but not limited to,
entering upon the Sub-Leased  Premises upon  reasonable  prior written notice to
Sub-Tenant and in the presence of an employee of  Sub-Tenant,  unless such entry
is on an emergency basis, to make repairs).  All rights given to Sub-Landlord in
this Section  shall be in addition to any other right or remedy of  Sub-Landlord
herein contained.

g.   Environmental Assurances/Obligations.
         
     (1) Sub-Tenant, covenants and warrants, on behalf of itself, its employees,
     agents, contractors, and/or invitees:

               (a)  that it will  not  cause or keep  in,  upon,  or  about  the
               Sub-Leased  Premises any Hazardous  Substances  (defined  below),
               except as permitted  below,  or in a manner which will contravene
               Sub-Landlord's  or  Landlord's  policies  of  insurance  insuring
               against  loss or  damage  by fire or  other  hazards  (including,
               without  limitation,  public  liability),  or which, will prevent
               Sub-Landlord  and/or  Landlord  from  procuring  such policies in
               companies and at premium rates acceptable to Sub-Landlord  and/or
               Landlord, in their sole and unreviewable discretion.

               (b) to comply with all obligations imposed by any applicable law,
               and   regulations   promulgated   thereunder,   and   all   other
               restrictions  and  regulations  upon the  Generation of Hazardous
               Substances by Sub-Tenant at, to or from the Sub-Leased  Premises;
              
               (c) to deliver  promptly to  Sub-Landlord  and Landlord  true and
               complete  copies of all notices  received by Sub-Tenant  from any
               governmental   authority   with  respect  to  the  Generation  by
               Sub-Tenant of Hazardous Substances (whether or not at, to or from
               the Leased Premises);

               (d) to complete fully, truthfully and promptly any questionnaires
               sent by SubLandlord or Landlord with respect to Sub-Tenant's  use
               of  the  Sub-Leased   Premises  and  SubTenant's   Generation  of
               Hazardous Substances;

               (e) to permit entry onto the Sub-Leased Premises by Sub-Landlord,
               Sub-Landlord's  representatives,  or Landlord  at any  reasonable
               time to  verify  and  monitor  Sub-Tenants  compliance  with  its
               representations,  warranties  and  covenants  set  forth  in this
               Section;

               (f) to pay to Sub-Landlord or Landlord,  as additional  rent, the
               costs Incurred by Sub-Landlord or Landlord  hereunder,  including
               the costs ofsuch monitoring and verification; and

               (g) to fumish to Sub-Landlord and Landlord,  at the expiration of
               the  Term or at the  sooner  termination  of the  Term as  herein
               provided,   a  certification   to   Sub-Landlord   and  Landlord,
               equivalent  to  that  provided  by  Sub-Landlord  below,  from an
               environmental   audit  company  acceptable  to  Sub-Landlord  and
               Landlord to the effect that,  based upon an inspection  conducted
               by such  environmental  audit  company  not more than thirty (30)
               days prior to the  expiration  or  termination  of the Term,  the
               Sub-Leased Premises are free from Hazardous Substances.

               (h) to obtain its own Hazardous  Waste Generator Site Number from
               the  applicable  Federal,  State  or Local  authorities  and will
               provide  Sub-Landlord  and Landlord with proof of such compliance
               as a pre-condition to its commencement of occupancy hereunder.
                
               (i) to obtain  its own  Radioactive  Use Permit  from  applicable
               Federal,   State  and  Local   authorities,   and  will   provide
               Sub-Landlord  and  Landlord  with proof of such  compliance  as a
               pre-condition to its commencement of occupancy hereunder.

               (j) to  store  any  hazardous  waste,  environmentally  sensitive
               materials,  radioactive  waste, or compressed gas in Sub-Landlord
               and  Landlord   approved  storage  areas  within  the  Sub-Leased
               Premises and in no other area. Sub-Tenant will be responsible for
               the costs of any tenant improvements associated with the creation
               of such storage areas within the Sub-Leased Premises.

               (k) to contact the appropriate local government authority for any
               necessary sewer discharge permits and, will provide  Sub-Landlord
               and Landlord with proof of such compliance as a pre-condition  to
               its commencement of occupancy hereunder.

                    (1) to designate a company  safety  director / contact prior
                    to occupancy of the  SubLeased  premises.  The  Sub-Tenant's
                    safety   director   will   be  the   primary   contact   for
                    SubLandlord's  safety director  regarding  compliance audits
                    and evacuation drills.

     (2) Sub-Tenant's  Indemnification.  Sub-Tenant agrees to indemnify and hold
     harmless SubLandlord and Landlord and their respective assignees,  from and
     against any and all costs, fees or expenses (including, without limitation,
     environmental  assessment,   investigation  and  environmental  remediation
     expenses,  third party  claims and  environmental  impairment  expenses and
     reasonable attomeys' fees and expenses) incurred by Sub-Landlord, Landlord,
     or their respective  assignees,  as a result of any Generation of hazardous
     Substances  at,  to  or  from  the  Leased  Premises  during  the  term  of
     Sub-Tenant's  use or occupancy  thereof or otherwise as a result of any act
     or  omission),  Sub-Tenant,  or as a result of any failure by Sub-Tenant to
     comply with its  representations,  warranties and covenants as set forth in
     this Section. 

     (3)  Sub-Landlord's  Indemnification.  Sub-Landlord  agrees  to  indemnify,
     defend and hold harmless Sub-Tenant from and all claims (including, without
     limitation,   environmental  assessment,  investigation  and  environmental
     remediation  expenses,  third  party  claims and  environmental  impairment
     expenses)   incurred  by  Sub-Tenant  in  connection  with   Sub-Landlord's
     Generation  of  Hazardous  Substances  at, to or from the  Leased  Premises
     during or prior to the Commencement date of the Term.

     (4) Definition of Hazardous Substance. The term "Hazardous Substance" means
     any pollutant,  contaminant,  toxic or hazardous waste,  infectious  waste,
     oil,  petroleum  products  and  their  by-products,   dangerous  substance,
     potentially  dangerous  substance,   noxious  substance,  toxic  substance,
     flammable,   explosive,   radioactive  material,   urea  formaldehyde  foam
     insulation,  asbestos,  PCB'S, or any other substances the removal of which
     is required, or the manufacture,  preparation, production, generation, use,
     maintenance,  treatment,  storage, transfer, handling or ownership of which
     is restricted,  prohibited,  regulated,  penalized by or subject to any and
     all federal,  state,  county,  or municipal  statutes or laws now or at any
     time hereafter in effect,  including but not limited to, the  Comprehensive
     Environmental Response,  Compensation,  and Liability Act (42 U.S.C. ss.ss.
     9601 et seq.), the Hazardous Materials Transportation Act (49 U.S.C. ss.ss.
     1801 et seq), the Resource  Conservation and Recovery Act (42 U.S.C. ss.ss.
     6901 et seq.),  the Federal Water Pollution  Control Act (33 U.S.C.  ss.ss.
     1251 et seq.), the Clean Air Act (42 U.S.C. ss.ss. 7401 et seq.), the Toxic
     Substances  Control Act, as amended (15 U.S.C.  ss.ss.  2601 et seq.),  the
     Occupational  Safety and Health Act (29  U.S.C.  ss.ss.  651 et seq.),  the
     Maryland  Environment  Code Ann.  ss.4-411(3)(i),  as amended  from time to
     time, and regulations  promulgated  thereunder;  the Maryland  Environrnent
     Code  Ann.,  Title  7,  subtitle  2, as  amended  from  time to  time,  and
     regulations promulgated thereunder;  the Maryland Environment Code Ann. ss.
     9-227,  as  amended  from  time  to  time,  and   regulations   promulgated
     thereunder,  as these laws have been amended or  supplemented  The term "To
     Generate"  means to use,  collect,  generate,  store,  transport,  treat or
     dispose of.

      (5) Sub-Landlord Warranties and Representations.

               (a)  With regard to the  Subleased  Premises  and the rest of the
               Building and any  adjoining  property to which  Sub-Landlord  has
               title  or  control  ("Total  Premises")   SubLandlord  covenants,
               represents and warrants to Sub-Tenant that to the best of its
               knowledge and understanding:

                    1.   As  of  the   Commencement   Date  of  this  Sub-Lease,
                    Sub-Landlord and the Leased Premises are each in substantial
                    compliance  with all  federal,  state,  county or  municipal
                    environmental,  pollution, health, safety, fire, or building
                    code  laws,  and  Sub-Landlord  has  no  knowledge  and  has
                    received  no  notice  of  any  federal,   state,  county  or
                    municipal enviromental,  pollution, health, safety, fire, or
                    building  code  violations  or  requirements  to clean up or
                    decontaminate the Property.

                    2.   Neither the Sub-Landlord nor any owner of the Property,
                    have been named as a party in any  proceeding or lawsuit for
                    violation of federal, state, or local environmental laws.
                         
                    3.   The  Leased  Premises  are  not  currently  subject  to
                    investigation   for  alleged  federal,   state,   county  or
                    municipal environmental, pollution, health, safety, fire, or
                    building code violations.

     (6) Disposal of Hazardous Substance. Upon the termination of this Sub-Lease
     and the tenancy created  thereby,  Sub-Tenant will cease to Generate and/or
     store  Hazardous  Substances,  and  will  make  necessary  and  appropriate
     arrangements  for the removal of same and their wastes from the  Sub-Leased
     Premises prior to its surrender of said Sub-Leased Premises to SubLandlord,
     in compliance with applicable laws.

     (7) Sub-Tenant's  obligations  regarding  Hazardous  Substance  Generation,
     storage  and  disposal  hereunder,  shall be  limited  to  those  Hazardous
     Substances  Generated by Sub-Tenant  or otherwise  Generated at or from the
     Subleased  Premises from the Commencement Date hereof up to and through the
     date of termination or expiration of the Sub-Lease or any Extension thereof
     and not thereafter, except as required by law.

     (8)  Each  Party's  respective  covenants,   warranties,   representations,
     indemnification,   defense  and  hold  harmless   obligations   under  this
     Subsection  (g)  shall  survive   expiration  and/or  termination  of  this
     Sub-Lease.

h.   Restrictions On Use In Prime Lease.

     (1)  Sub-Tenant  acknowledges  that it has  received and reviewed the Prime
Lease and those  covenants  and  restrictions  affecting  the use of the  Leased
Premises  set  forth in the  Prime  Lease and  agrees  to  maintain  and use the
Sub-Leased  Premises in accordance with those limitations and to be bound in all
respects  by the terms,  conditions,  covenants  and  restrictions  of the Prime
Lease,  subject,  however,  to  Sub-Landlord's  representation  and  warranty to
Sub-Tenant that the Sub-Tenant's uses of the Sub-Leased Premises as specified in
Exhibit F of this Sub-Lease do not contravene such Prime Lease.  Notwithstanding
anything to the  contrary,  in no event shall the  provisions of the Prime Lease
dealing  with  Rent  (Basic  or  Additional),  insurance,  tenant  improvements,
security or any other  payment,  performance  or guarantee  obligations  thereof
apply to this Sub-Lease and it is agreed and understood that Subtenant's payment
and  performance  obligations  are governed  solely by the express terms of this
Sub-Lease.
    
     (2) the  Sub-landlord  covenants  and  warrants to  Sub-Tenant  that it has
obtained  the all  consents  from the  Landlord,  the Bank and  MIDFA  which are
necessary for Sub-Landlord to enter into this Sub-Lease Agreement.

i.   Parking. Sub-Tenant shall be provided surface parking for employee, visitor
and guest parking, at no cost to Sub-Tenant,  for up to 40 cars, on a first-come
first-serve  use,  based on  Sub-Tenant's  pro-rated  share of space  under  the
Sub-Lease.

j.   Signs.  Sub-Landlord and Sub-Tenant agree to place an identifying marker on
the existing  sign location in the front parking lot which is part of the Leased
Premises  ("Joint Sign") and on a small Joint corner marker to be located at the
left front of the  building.  The Joint  Sign shall bear the names  "biosys/Gene
Logic, Inc.," or some reasonable facsimile thereof, as agreed to by the Parties,
and Sub-Landlord  shall provide  Sub-Tenant a $500.00 credit toward the creation
of said Joint  Sign,  with the  expenses  above  $500.00  to be evenly  split by
Sub-Tenant and  Sub-Landlord.  Sub-Tenant's sign shall comply in all respects to
state, county, HRD and all other regulations or requirements  governing such use
and must be approved in advance by Sub-Landlord and Landlord.

k.    Services.

      Sub-Landlord  shall  furnish  or  cause  the  Sub-Leased  Premises  to  be
furnished with:

     (1) electricity for lighting and the operation of the Occupied Premises and
otherwise  sufficient  electricity for equipment of Lessee  installed or allowed
pursuant to this Lease;

     (2) heat  and air  conditioning  reasonably  required  for the  comfortable
occupation of the Occupied  Premises  during Normal Business Hours (8:30 a.m. to
5:30 p.m);
        
     (3) access to the Building and parking facilities at all times;

     (4) lighting  replacement  (for Building  standard  lights),  during Normal
Business Hours;

     (5) hot and cold water and restroom supplies and cleaning;

     (6) cleaning and char service in the Occupied Premises during the times and
in the manner that
those services are furnished by Sub-Landlord in its own Premises;

          Sub-Landlord grants Sub-Tenant, its employees, invitees, licensees and
     other  visitors  the right to use the common  areas of the Building and the
     property covered by the Prime Lease (including, without limitation, parking
     areas,  sidewalks,  and  corridors).  Sub-Landlord  agrees to maintain  and
     repair  the  common  areas  throughout  the term and any  extension  of the
     SubLease;  and to maintain  public  liability  insurance  for  injuries and
     damage occurring in the conunon areas in such amounts as required under the
     provisions  of the Prime Lease.  Notwithstanding  anything to the contrary,
     Sub-Landlord  shall  not close or change  the  common  areas in a way as to
     alter or diminish the quantity,  quality,  utility or character  thereof or
     limit  Sub-Tenant's  ease of access to or use of its  Sub-Leased  Premises,
     except in the event of a bona fide emergency on a temporary basis, and then
     in a manner which minimizes any adverse impact on Sub-Tenant.
          
          Any  failure  by  Sub-Landlord  to  furnish  the  foregoing  services,
     resulting from circumstances  beyond  Sub-Landlord's  reasonable control or
     from interruption of such services due to repairs or maintenance, shall not
     render  Sub-Landlord  liable in any respect for damages to either person or
     property,  ilor be  construed  as an eviction of  Sub-Tenant,  nor cause an
     abatement  in  rent  hereunder,  nor  relieve  Sub-Tenant  from  any of its
     obligations  hereunder.  If any public uti 'lity or governmental body shall
     require  Sub-Landlord  or  Sub-tenant  to restrict the  consumption  of any
     utility or reduce any service for the Sub-Lease Premises,  Sub-Landlord and
     Sub-Tenant  shall  comply  with  such  requirements,  whether  or  not  the
     utilities and service referred to in this Section k. are thereby reduced or
     otherwise  affected,  without any liability on the part of  SubLandlord  to
     Sub-Tenant  or any other  person or any  reduction  or  adjustment  in rent
     payable hereunder.  Notwithstanding  the foregoing,  if the interruption of
     such services shall continue for more than forty (40) consecutive days from
     the date of the initial interruption, Sub-Tenant's sole remedy shall be the
     right to terminate this Sub-Lease.

4.   Insurance. Sub-Tenant shall maintain commercial general liability insurance
in respect  to its  occupancy  and use of the  Sub-Leased  Premises,  naming the
Sub-Landlord and Landlord as additional insureds, which insurance shall be in an
amount not less than  $2,000,000.00  per  occurrence  and  $5,000,000.00  in the
aggregate.

     Sub-Tenant  shall  maintain  at  all  times  all  risk  personal   property
insurance,   written  at  replacement  cost  value  and  with  replacement  cost
endorsement covering Sub-Tenant's property, the property of Sub-Landlord and the
property of the Landlord located in the Sub-Leased Premises and covering loss of
income  resulting from casualty,  which  insurance  shall name  Sub-Landlord  or
Landlord,  as the case may be, as the loss payee with regard to the  property of
such entity .

     Sub-Tenant  shall  maintain  worker's  compensation  insurance  or  similar
insurance policy offering  statutory  coverage and containing  statutory limits,
which policy shall also provide  Employer's  Liability Coverage of not less than
Five Hundred Thousand Dollars ($500,000.00) per occurrence.
       
     Sub-Tenant  shall require any  construction  contractor  retained by it and
approved by SubLandlord and Landlord to perform work on the Sub-Leased  Premises
to carry and  maintain,  at no  expense  to  Sub-Landlord,  during  such time as
contractor is working in the Sub-Leased Premises, a commercial general liability
insurance  policy  in an amount  not less than  $1,000,000  per  occurrence  and
$2,000,000  in the  aggregate  and  worker's  compensation  insurance or similar
insurance in form and amounts required by law.

     At all times throughout the term of this Lease,  Sub-Landlord will maintain
in effect such insurance as required under Section 9 of the Prime Lease.

5.   Mechanics'  and  Materialmen's  Liens and  Other  Liens.  Sub-Tenant  shall
discharge or bond off, within Ten (10) days after the date it receives notice of
filing,  any  mechanics' or  materialmen's  liens filed  against the  Sub-Leased
Premises (or Sub-Tenant's interest therein), or any part thereof,  purporting to
be for work or material furnished or to be furnished to Sub-Tenant,  and it will
provide  Sub-Landlord  notice of any such liens within Five (5) days that notice
of such is received by Sub-Tenant.

6.       [Intentionally Omitted]

7        Right of Entry.

         a. Access by Sub-Tenant. Sub-Landlord agrees to furnish Sub-Tenant with
      keys to the exterior doors on the  western-side of the building which will
      allow Sub-Tenant direct access to all portions of the Sub-Leased  Premises
      twenty-four  hours a day,  seven  days a week.  Sub-Tenant  shall bear any
      costs  associated  with the  separate  zoning of the  currently  installed
      security system in the building to cover only the Sub-Leased  Premises and
      upon approval Sub-Tenant shall pay the reasonable costs thereof.

         b. Access by Sub-Landlord,  Sub-Landlord,  Landlord or their respective
      agents  shall  have the  right to enter  the  Sub-Leased  Premises  at all
      reasonable  times  for the  purpose  of  inspection  or by  reason  of the
      requirements  of public  authorities;  provided,  however,  SubLandlord or
      Landlord,  as the case may be, shall provide reasonable notice of any such
      inspections, to the extent possible.

8.    [Intentionally Omitted].

9.    Ownership of Improvements to Sub-leased Premises and Equipment Therein.

          (1)  Sub-Tenant  agrees that it will not undertake  any  structural or
     non-structural  alterations  of any of the  improvements  erected  upon the
     Sub-Leased Premises,  nor construct any new structures or improvements upon
     the Sub-Leased Premises,  without the prior written consent of Sub-Landlord
     and Landlord following Sub-Tenant's submission to Sub-Landlord of plans and
     specifications   with  respect   thereto,   which   consent  shall  not  be
     unreasonably  withheld  by  Sub-Landlord  and  Landlord  so  long  as  such
     alterations  will not  materially  change  the  character  of the  existing
     improvements  or weaken or impair the  structural  integrity  or lessen the
     value of the existing  improvements.  In all other cases,  Sub-Landlord and
     Landlord's consent shall be given solely within  Sub-Landlord and Landord's
     discretion.  Sub-Tenant  shall deliver to  Sub-Landlord  a  certificate  of
     occupancy when required by law, as a condition  precedent to the use of the
     improvements  for their  designated  purpose.  Upon  completion  of any new
     structural  improvements,  Sub-Tenant  shall  deliver to  Sub-Landlord  and
     Landlord a set of the "as built" plans.

          (2)  Sub-Tenant  shall  maintain the  construction  site in a neat and
     orderly manner and shall be responsible,  at its sole cost and expense, for
     removing all construction debris.
        
          (3) All such work,  other than movable  furniture  or trade  fixtures,
     done by SubTenant  upon the Sub-Leased  Premises,  shall be the property of
     the Landlord at the termination of this Sub-Lease;  provided, however, that
     Sub-Landlord  or Landlord may require  Sub-Tenant to remove all or any part
     of said work at the  expiration  of this  Sub-Lease,  in which  event  such
     removal  shall be done at  Sub-Tenant's  sole cost and  expense.  SubTenant
     shall,  at its sole cost and expense,  repair any damage to the  Sub-Leased
     Premises  and/or the  Building  caused by such removal or by the removal of
     this personalty. Notwithstanding the foregoing, Sub-Landlord and Sub-Tenant
     hereby agree that  SubLandlord  and Landlord will make a  determination  of
     whether  any  such  work  must  be  removed  by   Sub-Tenant  at  the  time
     Sub-Landlord and Landlord review the proposed plans and  specifications for
     such  work,  and such  determination  shall  be  binding  on  Sub-Landlord,
     Landlord  and  Sub-Tenant.  To the extent that  Sub-Landlord  and  Landlord
     determine that any offices or  laboratories to be constructed by Sub-Tenant
     could be used by a subsequent subtenant and would not hinder the Landlord's
     ability to re-lease the Building in the general marketplace for offices and
     laboratories,  Sub-Landlord  and Landlord will not require that the same be
     removed  by  Sub-Tenant  upon  the  expiration  of the  Lease  Term,  which
     determination  will be made by  Sub-Landlord  or Landlord as an exercise of
     their unreviewable discretion, as the case may be.
         
          (4) Any and all  laboratory  equipment,  furniture and other  personal
     property  ("Property")   contained  in  the  Sub-Leased  Premises,  and  as
     reflected in the inventory attached hereto as Exhibit G, is the property of
     the Sub-Landlord or the Landlord as appropriate  under the Prime Lease, and
     while  Sub-Tenant  is  permitted  to use such  Property  during the Term or
     Extension hereof, such Property may not be removed from the Sub-Premises or
     otherwise  modified  or  disposed  of by the  Sub-Tenant  without the prior
     written permission of the Sub-Landlord or the Landlord, as the case may be.
     If the Property  described on Exhibit G is  repossessed  at any time during
     the term of this SubLease Sub-Tenant shall have the right to terminate this
     Sub-Lease Agreement.

          (5) Sub-Landlord shall make improvements set forth in Exhibit H to the
     SubLeased Premises at its sole cost.
       
          (6) Sub-Tenant  shall make  improvements set forth in Exhibit I to the
     Sub-Leased  Premises  at  its  sole  cost  and  expense.  Upon  substantial
     completion  of  all  improvement  made  by  Sub-Tenant  to  the  Sub-Leased
     Premises,  Sub-Tenant  shall  provide  Sub-Landlord  with  a  complete  and
     detailed list of all such improvements.

10.  Default by Sub-Tenant and Sub-Landlord's Remedies.

          a. The following may be deemed events of default: (i) Sub-Tenant shall
     breach  the  covenant  to pay rent by  failing to pay rent ten (10) or more
     days from the date when due; or, (ii) any petition or other  proceeding  is
     filed by or  against  Sub-Tenant  under the  Federal  Bankruptcy  Code,  as
     amended,  or any  proceeding  provided by the applicable law of Maryland in
     the nature of a bankruptcy or for the benefit of creditors  which  petition
     is not dismissed  within sixty (60) days; or, (iii) Sub-Tenant shall become
     insolvent-,  or, (iv) SubTenant shall make an assignment for the benefit of
     creditors;  or, (v) a rcceiver is appointed for the substantial part of the
     assets of Sub-Tenant,  which appointment is not dismissed within sixty (60)
     days; or, (vi) the leasehold  interest is levied under execution,  in which
     case  Sub-Landlord  shall have the option to do the  following set forth in
     this Section 10, in addition to and not in  limitation  of any other remedy
     permitted by law or by this SubLease.

          b. With the  exception of a failure to timely pay rent as set forth in
     Subsection  (a) herein for which there shall be no  opportunity to cure, in
     the event of  Sub-Tenant's  default and failure to cure said default within
     twenty (20) days, Sub-Landlord may terminate this Sub-Lease, in which event
     Sub-Tenant  shall   immediately   surrender  the  Sub-Leased   Premises  to
     Sub-Landlord,  but if  Sub-Tenant  shall fail to do so,  Sub-Landlord  may,
     without   further  notice  and  without   prejudice  to  any  other  remedy
     Sub-Landlord  may have for  possession  or arrearage in rent or damages for
     breach of contract, enter upon the SubLeased Premises and remove Sub-Tenant
     and his effects in accordance with applicable  laws, if necessary,  without
     being liable to prosecution or any claim for damages,  and SubTenant agrees
     to indemnify  Sub-Landlord for all loss and damages which  Sub-Landlord may
     suffer by reason of such  termination,  whether through  inability to relet
     the  SubLeased  Premises,   or  through  decrease  in  rent  or  otherwise,
     Sub-Landlord  may at his option declare the entire amount of the rent which
     would  become  due and  payable  during  the  remainder  of the  term to be
     immediately due and payable,  in which event  Sub-Tenant  agrees to pay the
     same  at  once,  together  with  all  rents  and  additional  rents  due to
     SubLandlord.
     
          c. Such  payments  shall not  constitute  a penalty or  forfeiture  or
     liquidated damages,  but shall merely constitute payments in advance of the
     rent for the remainder of the term.

          d. Pursuit of any of the foregoing remedies shall not preclude pursuit
     of any of the other  remedies  provided  by this  Sub-Lease  or by law.  If
     Sub-Landlord  shall  incur  any  expense  including,  but not  limited  to,
     reasonable  attorneys' fees and costs, as the result of Sub-Tenant's breach
     of any covenant or term of this Sub-Lease, the amounts so incurred shall be
     payable to Sub-Landlord as additional rent by Sub-Tenant.

11.  Sub-Tenant's Remedies for Sub-Landlord's  Default. In the event of a breach
of this SubLease by Sub-Landlord, and Sub-Landiord's failure to cure such breach
within twenty (20) days,  Sub-Tenant  shall have the right to file an action for
damages  or  specific  performance  at law or  equity  in a court  of  competent
jurisdiction in Howard County, Maryland, and if Sub-Tenant prevails,  whether in
court or by  negotiation  or  mediation,  and  Sub-Landlord  shall pay all court
costs,  litigation  and  mediation  expenses  and  attorney's  fees  incurred by
Sub-Tenant.

12. Loss, Damage, Injury.

     a. No Liability for  Sub-Tenant's  Property.  Sub-Tenant  hereby  expressly
agrees that neither  Sub-Landlord nor Landlord shall be liable or responsible in
any manner for any damage or destruction to the property of Sub-Tenant or of any
other person or entity and/or for injury or death to the person of Sub-Tenant or
of any other person or entity directly or indirectly due to any cause whatsoever
other  than the  willful  misconduct  or  negligence  of or by  Sub-Landlord  or
Landlord,  as the  case  may be,  or  their  respective  contractors,  servants,
employees, agents, licensees and/or invitees.
      
     b. Indemnity.  Sub-Tenant,  Landlord and Sub-Landlord  shall each indemnify
and hold  harmless  the other from and against all losses,  costs and  expenses,
settlement payments (if such settlement is approved by the other, which approval
shall not be  unreasonably  withheld or delayed)  and all  liabilities,  damages
and/or fines paid, incurred or suffered by the other party: (i) by reason of any
breach,  violation and/or non-performance by the other or that party's servants,
employees,  agents,  licensees or invitees, of any covenant or provision of this
Sub-Lease;  (ii) by reason of or arising out of the occupancy or use of the Real
Property,  or any part thereof,  including any claim action, suit or proceeding,
threatened,  instituted  and/or  made  against  the other  arising  out of or in
connection  therewith;  and/or, (iii) from any other cause whatsoever due to the
negligence,  or  willful  misconduct  of the  other  or that  party's  servants,
employees, agents, licensees and/or invitees. This indemnification shall survive
the termination or expiration of this SubLease, to the extent permitted by law.

13.  Destruction  By Fire  or.Other  Casualty.  In the event of partial or total
damage or destruction to the Leased  Premises by fire,  other  casualty,  or any
other cause  whatsoever,  the terms and  conditions  of the Prime Lease shall be
controlling,   and  Sub-Tenant's   rights   thereunder  shall  be  the  same  as
Sub-Landlord's.

14.  Recognition  of Prime Lease.  To the extent not  otherwise  provided for in
this  Sub-Lease,  Sub-Tenant  agrees that this Sub-Lease shall be subject to and
subordinate  to the terms and  conditions of the Prime Lease and any existing or
future assignments, liens, mortgages or other encumbrances which Sub-Landlord or
Landlord place upon the Leased Premises or Sub-Lcased Premises.

15.  Eminent  Domain.  If the entire Leased  Premises,  including the Sub-Leased
Premises,  shall be substantially  taken (either temporarily or permanently) for
public  purposes,  or in the event  Landlord  shall  convey or lease the  Leased
Premises and/or Real Property to any public  authority in settlement of a threat
of condemnation or taking,  the terms and conditions of the Prime Lease shall be
controlling,   and  Sub-Tenant's   rights   thereunder  shall  be  the  same  as
Sub-Landlord's.

16.  Assignment.  Sub-Tenant,  for  itself,  its heirs,  distributees,  personal
representatives,  legal  representatives,   successors  and  assigns,  expressly
covenants that it shall not further assign, mortgage or encumber this Sub-Lease,
nor Sub-Lease or use or permit the Sub-Leased Premises or any part thereof to be
used by  others,  without  the prior  written  consent of  Sub-Landlord  in each
instance,  which consent shall not be unreasonably  withheld.  In the event that
Sub-Landlord  shall give such  consent,  Sub-Tenant  shall  nevertheless  remain
primarily  liable for the termss of this SubLease and shall not be relieved from
any liability  whatsoever under the Lease.  Sub-Tenant shall bear the reasonable
legal review costs incurred by  Sub-Landlord  in connection with such assignment
or subleasing. Sub-Tenant may assign this Sub-Lease or sublet all or any portion
of the Sub-Leased Premises to another entity which is wholly owned by Sub-Tenant
or  Sub-Tenant's  parent  company  (each,  an  "Affiliate")  without any further
consent from  Sub-Landlord,  so long as  Sub-Tenant  nevertheless  remains fully
liable under this Sub-Lease.  In the event that the amount of rent to be paid to
Sub-Tenant  by an assignee or sublessee is greater than the rent  required to be
paid by SubTenant to Sub-Landlord pursuant to this Sub-Lease,  such excess shall
be the property of SubLandlord. Any levy or sale in execution, or any assignment
or sale in bankruptcy or insolvency, or the appointment of a receiver or trustee
of any of the  property  of  Sub-Tenant  by a state or federal  court,  shall be
deemed an assignment within the meaning of this Section.

17.  Non-Disturbance. Sub-Landlord agrees not to disturb or in any way interfere
with SubTenant's lawful use and enjoyment of the Sub-Leased  Premises during the
Term hereof, or any Extension of the Tenn. The Sub-Landlord covenants and agrees
with the Sub-Tenant  that, upon the Sub-Tenant  paying the Rent reserved in this
Sub-Lease and observing and performing all the tenus, covenants,  and conditions
of this Sub-Lease on the  Sub-Tenant's  part to be observed and  performed,  the
Sub-Tenant may peaceably and quietly enjoy the full possession of the Sub-Leased
Premises  without  molestation  or hindrance  during the term of this  Sub-Lease
(including any Extension period), in accordance with the terms,  covenants,  and
conditions of this Sub-Lease and  Sub-Tenant's use and enjoyment of the Premises
will  not  be  disturbed.   Sub-Tenant   acknowledges  that  this  agreement  by
Sub-Landlord, as set forth in Section 17, in no way limits or affects Landlord's
rights under the Prime Lease,  including the right to terminate same and thereby
ten-ninate  this  Sub-Lease.  Sub-Landlord  agrees that the  foregoing in no way
limits any cause of action Sub-Tenant may have against Sub-Landlord for a breach
of this Section 17.

18.  Notices.  All notices,  demands and requests  required under this Sub-Lease
shall be in writing and shall be mailed by United States registered or certified
mail, return receipt requested,  postage prepaid, or by Federal Express or other
nationally  recognized  overnight  courier  service,  or  hand-delivered  with a
receipt and addressed (1) if to Landlord, c/o Manekin Corporation, 7165 Columbia
Gateway Drive, Columbia,  Maryland 21046, Attn.: General Counsel, with a copy to
Ann Clary  Gordon,  Esquire,  c/o Shapiro and  Olander,  36 S.  Charles  Street,
Baltimore, Maryland 21201 or (ii) if to Sub-Landlord, at the Leased Premises, to
Dr. Edwin Quattlebaum,  President/CEO,  with a copy to William P. Cook, Esquire,
c/o Borinsky;  Ramsey & Cook,  LLC,  Suite 250, 10420 Little  Patuxent  Parkway,
Columbia,  Maryland  21044,  and (iii) if to Sub-Tenant to Dr. Michael  Brennan,
President/CEO,  at  the  Sub-Leased  Premises.  All  notices  delivered  in  the
foregoing  manner shall be deemed  delivered  on the date the return  receipt is
executed  or the  date  the  recipient  refuses  delivery.  Notwithstanding  the
foregoing,  all rental  payments and other charge due under this Sub-Lease shall
be  delivered to  Sub-Landlord  at the address of  SubLandlord  set forth above,
Attn.:  Accounting  Department.  Any of such  entities may designate a change of
address by written notice to the others.

19.  Estoppel Certificates.  Each party agrees to any time and from time to time
upon not less than five (5)  business  days prior  notice by the other  party to
execute,  acknowledge and deliver to the requesting party a statement in writing
certifying that this Sub-Lease is unmodified and in full force and effect (or if
there  have been  modifications,  that the same is in full  force and  effect as
modified  and  stating  the  modifications)  and the dates to which the Rent and
other charges have been paid in advance,  if any, and stating whether or not, to
the best knowledge or the signer of such certificate, the requesting party is in
breach and/or  default in  performance  of any covenant,  agreement or condition
contained  in the  Sub-Lease  and, if so,  specifying  each such  breach  and/or
default in performance of any covenant, agreement or condition contained in this
Sub-Lease  and, if so,  specifying  each such breach and/or default of which the
signer may have knowledge. Such statement delivered hereunder may be relied upon
by any party not a party to this Sub-Lease.

20.  Attornment.  Sub-Tenant  agrees that upon any termination of Sub-Landlord's
or Landlord's  interest in the Leased Premises,  Sub-Tenant shall, upon request,
attorn to the holder of the Sub-Landlord's  interest in the Leased Premises (the
"Successor")  and to all  subsequent  Successors  (provided  that such Successor
enters  into a  non-disturbance  agreement  in  form  reasonably  acceptable  to
Sub-Tenant and the Successor) and shall pay to the Successor all rents and other
monies required to be paid by the  Sub-Tenant,  hereunder and perform all of the
other covenants, agreements,  provisions,  conditions, obligations and/or duties
of Sub-Tenant contained in this Sub-Lease.

21. Severability and Enforceability.  If any term or provision of this Sub-Lease
or the application thereof to any person or circumstances  shall, to any extent,
be invalid or unenforceable,  the remainder of this Sub-Lease or the application
of such term or  provision  to persons or  circumstances  other than those as to
which it is held invalid or unenforceable,  shall not be affected  thereby,  and
each term and provision of this Sub-Lease  shall be valid and enforceable to the
fullest extent permitted by law.

22.  Recordation.  Sub-Tenant  covenants  that if at any time any  mortgagee  of
Landlord's  interest in the Leased Premises,  any trustee or beneficiary under a
deed of trust  constituting  a lien  upon the  Building  of which  deed of trust
Landlord is grantor,  or a landlord of Landlord in respect of the real  property
upon which the  Building is  situated,  shall  require the  recordation  of this
SubLease,  or if any recordation is required by Sub-Landlord or its assigns,  or
if the  recordation  of this Lease shall be  required by any valid  governmental
order, or if any governmental  authority having jurisdiction in the matter shall
assess and be entitled to collect transfer taxes or documentary  stamp taxes, or
both such taxes on this Sub-Lease, Sub-Tenant shall execute such acknowledgments
as may be necessary to effect such recordation and whichever party requires such
recordation  shall pay all recording fees,  transfer taxes and documentary stamp
taxes payable on, or in connection with, this Sub-Lease or such recordation.

23. Successors and Assigns.  The covenants,  conditions and agreements contained
in this Lease shall bind and inure to the benefit of Landlord,  Sub-Landlord and
Sub-Tenant and their respective heirs, distributees,  executors, administrators,
successors,  personal and legal representatives and their permitted assigns. The
Bank and  MIDFA  shall  have no  liability  under  this  Sub-Lease  unless  they
expressly,   and  in  writing,  assume  Sub-Landlord's   agreements  under  this
Sub-Lease.

24.  Commissions  and Fees.  Except as provided in the Prime  Lease,  each party
shall be solely responsible for their own commissions and fees,  including,  but
not  limited,  to real  estate  brokers and  attomeys,  for which that party has
contracted  and neither party shall be responsible  for any  commissions or fees
which arise through or from any third party in respect to this  transaction  and
the parties  agree to hold  harmless and  indemnify  the other in respect to all
such fees and commissions.

25.   Termination of Sub-Lease.

      a.  Termination  of  Tenancy_-  The  Sub-Lease   created  hereunder  shall
      terminate by its own terms on April 30, 2001,  unless  extended in writing
      and agreed to by the  parties as  otherwise  set forth  herein.  No act or
      thing  done by  Sub-Landlord  shall be  deemed  to be an  acceptance  of a
      surrender of the Sub Leased Premises unless and until  Sub-Landlord  shall
      execute a written release of Sub-Tenant.  Sub-Tenant's liability hereunder
      shall  not  be  terminated  by the  execution  of a new  sub-lease  of the
      Sub-Leased  Premises by  SubLandlord,  regardless  of the term of such new
      lease.

      b. Surrender of Premises.  Upon  termination of the Sub-Lease,  Sub-Tenant
      shall have the right to remove its personal property and equipment, agreed
      to and  identified  by the parties  and  Landlord  during a  pre-surrender
      inspection  of the  Sub-Leased  Premises  seventy-two  (72) hours prior to
      surrender of the Sub-Leased Premises by Sub-Tenant. SubTenant shall repair
      any  surfaces  damaged from the removal of any of its said  property,  and
      surrender the Sub-Leased Premises broom clean and ready for occupancy.

      c. Holding Over. If Sub-Tenant holds possession of the Sub-Leased Premises
      after  termination  of  this  Sub-Lease  without   Sub-Landlord's  written
      consent,  Sub-Tenant shall become a Sub-Landlord  from  month-to-month  at
      double the rent payable during the final year of the Term or any Extension
      hereof and upon all other terms herein  specified and shall continue to be
      such  Sub-Landlord  from  month-to-month   until  such  tenancy  shall  be
      terminated  by either  party giving the other  written  notice of at least
      thirty (30 ) days of its  intention to  terminate  such  tenancy.  Nothing
      contained in this Sub-Lease nor this Subsection c. specifically,  shall be
      construed as consent by the Sub-Landlord to the occupancy or possession of
      the Sub-Leased Premises by Sub-Tenant after termination of this Sub-Lease.
      Upon termination of this Sub-Lease,  Sub-Landlord shall be entitled to the
      benefit of all public  general or public local laws relating to the speedy
      recovery  of  the   possession  of  lands  and  tenements   held  over  by
      Sub-Landlords, that may now or hereafter be in force.

26.  Governing  Law.  This  Sub-Lease  shall be  governed  by and  construed  in
accordance with the laws, ordinance and regulations of the state of Maryland.

27.  Third  Party-Beneficiaries.  Nothing  contained in this Sub-Lease  shall be
construed  so as to confer  upon any other  party  the  rights of a third  party
beneficiary, other than those provided for herein.

28.  Complete  Agreement..  This  writing is  intended by the parties as a final
expression of their  agreement and is a complete and exclusive  statement of its
terms, and all negotiations,  considerations,  and  representations  between the
parties are  incorporated.  No course of prior  dealings  between the parties or
their affiliates shall be relevant or admissible to supplement, explain, or vary
any of the terms of this Sub-Lease.  Acceptance of, or acquiescence to, a course
of performance  rendered under this Sub-Lease or any prior agreement between the
parties or their affiliates shall not be relevant or admissible to determine the
meaning  of any of the  terms or  covenants  of this  Sub-Lease.  Other  than as
specifically set forth in this Sub-Lease, no representations, understandings, or
agreements have been made or relied upon in the making of this Sub-Lease.

29.  Modification.  This  Sub-Lease  can only be modified in writing,  signed by
each of the  parties  or their  agents.  Copies of any  modification(s)  to this
Sub-Lease shall be provided to Landlord, Bank and MIDFA.

30.  Captions.  All headings anywhere  contained in this Sub-l,ease are intended
for convenience of reference only and are not to be deemed or taken as a summary
of the provisions to which they pertain or as a construction thereof.

31.  Waiver  of  Jury  Trial.   Sub-Landlord  and  Sub-Tenant  desire  a  prompt
resolution of any  litigation  between them with respect to this  Sub-Lease.  To
that end,  Sub-Landlord and Sub-Tenant waive trial by jury in any action , suit,
proceeding  and/or  counterclaim  brought  by  either  against  the other on any
matters  whatsoever  arising out of or in any way connected with this Sub-Lease,
the relationship of Sub-Landlord  and Sub-Tenant,  Sub-Tenant's use or occupancy
of the Sub-Leased  Premises,  any claim of injury or damage and/or any statutory
remedy.  This  waiver  is  knowingly,  intentionally  and  voluntarily  made  by
Sub-Tenant.  Sub-Tenant  acknowledges  that neither  Sub-Landlord nor any person
acting on behalf of Sub-Landlord has made any  representations of fact to induce
this  waiver  of trial by jury or in any way to modify or  nullify  its  effect.
Sub-Tenant  further  acknowledges  that it has been  represented (or has had the
opportunity to be  represented)  in the signing of this Sub-Lease and the making
of this waiver by independent legal counsel,  selected of its own free will, and
that it has had the opportunity to discuss this waiver with counsel.  Sub-Tenant
further   acknowledges  that  it  has  read  and  understands  the  meaning  and
ramifications of this waiver of jury trial.

32.  Gender. As used in this Lease: (1) the masculine shall be deemed to include
the feminine and neuter and vice-versa;  and (2) the singular shall be deemed to
include the plural and vice-versa.

33.  Authority.  Sub-Tenant  warrants  to  Sub-Landlord  that  Sub-Tenant  is  a
corporation  organized and validly  existing in good standing  under the laws of
the  State  of  Delaware  and  qualified  to  transact  business  in the Sate of
Maryland.  In addition,  Sub-Tenant warrants to Sub-Landlord that this Lease has
been  properly  authorized  and  executed  by  Sub-Tenant  and is  binding  upon
SubTenant in accordance with its terms.  Sub-Tenant's  resident agent's name and
address in the State of Maryland is: The  Corporation  Trust,  32 South  Street,
Baltimore, Maryland 21202.

34.  Force  Majeure.  In the event that either  party hereto shall be delayed or
hindered  in or  prevented.  by reason of  weather,  strikes,  lock-outs,  labor
troubles,   inability  to  procure  materials,  failure  of  power,  restrictive
governmental laws or regulations, riots, insurrection. war, Acts of God or other
reason of a like  nature  (excluding  lack of funds)  not the fault of the party
delayed from  performing  work or doing any act required under the terms of this
Lease, then performance of such act shall be excused for the period of the delay
and the period of the performance of any such act shall be extended for a period
equivalent  to the period of such delay.  The party so delayed shall give prompt
notice  thereof to the other party.  The provisions of this Section 34 shall not
operate to excuse SubTenant from prompt payment of rent,  additional rent or any
otlier payments required by the terms of this Lease.

                       [SIGNATURES ON NEXT PAGE]



<PAGE>



IN WITNESS WHEREOF,  the parties affix their hands and seals on the day and year
first above written.



SUB-TENANT:

GENE LOGIC, INC.



_________________                   _________________________(SEAL)
Date                                By: Michael Brennan, PhD
                                    President and Chief Executive Officer


SUB-LANDLORD:

CROP GENETICS INTERNATIONAL CORPORATION/ biosys, INC.


________________                    __________________________(SEAL)
Date                                By:  Michael Thomas
                                    Vice President and Chief Financial Officer
                                    CROP GENETICS INTERNATIONAL CORPORATION

_______________                     __________________________(SEAL)
Date                                By:  Michael Thomas
                                    Vice President and Chief Financial Officer
                                    biosys, inc.

Landlord  signs below for the sole purpose of  acknowledging  its consent to the
above SubLease to Gene Logic,  Inc. upon the express condition that such consent
shall not be deemed a waiver  or  relinquishment  of the  covenant  against  any
future  assignment or subletting of the Prime Lease by Sub-Landlord,  or of this
Sub-Lease by Gene Logic, Inc., nor shall such consent in any way be construed as
releasing  Sub-Landlord  from the full performance of its obligations  under the
Prime Lease.



LANDLORD: M.O.R. XVIII ASSOCIATES LIMITED PARTNERSHIP


________________                    __________________________(SEAL)
Date                                By:  RA & DM, Inc.




<PAGE>


                                Site Plan Drawing
                                    Exhibit A




<PAGE>



                                 LEASE AGREEMENT


         THIS  AGREEMENT OF LEASE is made this 1st day of October,  1992, by and
between M.O.R.  XVIII  ASSOCIATES  LIMITED  PARTNERSHIP,  a limited  partnership
formed  under  the laws of the State of  Maryland  (hereinafter  referred  to as
"Landlord"), and CROP GENETICS INTERNATIONAL CORPORATION, a Delaware corporation
(hereinafter referred to as "Tenant").

         WITNESSETH,  that the  parties  hereby  covenant,  promise and agree as
follows:

     1.   Leased Premises.

          (a)  Landlord  is the  owner of a  building  containing  approximately
          75,500  square  feet (the  'Building')  constructed  on land leased by
          Landlord  and  designated  as  Parcel  M-2  (the  'Land')  on the Plat
          entitled,  "Parcels M-2 and M-3, A  Resubdivision  of Parcel M-1, Plat
          No.  5194",  which plat is recorded  among the Land  Records of Howard
          County,  Maryland as Plat No. 5693. The Land contains approximately 11
          acres, is located at 10150 Columbia Road in the Rivers  Corporate Park
          (the "Park",) in Howard County,  Maryland (the "County"),  and is more
          particularly  shown on  Exhibit  A  attached  hereto  incorporated  by
          reference herein and initialed by the parties. The Land, the Building,
          the  easements  and  rights   appurtenant   thereto  (including  those
          established by certain declarations of covenants recorded prior hereto
          among the Land Records of the County) , and the  sidewalks,  areaways,
          parking  areas,   driveways,   loading.   areas,   gardens  and  lawns
          surrounding  the  Building  and  located on the Land are  collectively
          hereinafter called 'Leased Premises'.  Landlord does hereby lease unto
          Tenant, and Tenant does hereby rent from Landlord, the Leased Premises
          for the  'Lease  Term'  (as  hereinafter  defined).  See  Rider  No. 2
          Expansion Option,  Rider No. 3 - Right of First Offer, and Rider No. 4
          - Right of First Refusal (Expansion Parcel).

          (b)  The  Leased  Premises  shall be  delivered  to Tenant in  "AS-IS"
          condition.   The  Leased   Premises   shall  include  all   furniture,
          telephones,  equipment  procedure manuals and all phone,  security and
          energy  management  systems now  located  therein  (collectively,  the
          'Equipment and Furnishings').  Landlord acknowledges that Tenant plans
          extensive  renovations to the Leased Premises which are being designed
          now, all of which shall be performed by Tenant,  at Tenant's sole cost
          and  expense.  All  improvements  to be made by Tenant  to the  Leased
          Premises  shall be made in accordance  with Section 6 below.  Landlord
          shall be given  the  opportunity  to  submit a bid to  Tenant  for the
          construction of such improvements. If Landlord is awarded the contract
          to perform such improvements,  the Leased Premises shall be thoroughly
          cleaned by Landlord,  at  Landlord's  sole cost and expense,  prior to
          Tenant's move-in.

     2.   Term.This  Lease shall be for a term (the 'Lease Term")  commencing on
     September 1, 1992 (the "Comencement Date") and terminating at 11:59 p.m. on
     November 30, 2004,  unless  otherwise  extended or terminated in accordance
     with the provisions  hereof. See Rider No. 5 - Renewal Option and Rider No.
     6 Cancellation Option.

          Each  respective  period of twelve  (12)  successive  calendar  months
     during the  _________________of  shall be  hereinafter  referred  to-as the
     lease year. The first lease year, however,  will be comprised of the of the
     period from the  Commencement  Date until  November 30, 1993,  so that each
     lease year thereafter will commence on December 1.
       
          The  Occupancy  Date,  shall be that  date on which  the  first of the
     following  events  occurs:  (a) the date on which the Leased  Premises  are
     ready for occupancy' as hereinafter  defined,  (b) the date on which Tenant
     shall take  possession or occupy all or any portion of the Leased  Premises
     (other than  occupying  the Leased  December 1, 1992.  The Leased  Premises
     shall be deemed  "ready for  occupancy"  on that date on which the  initial
     renovations to be made by Tenant on the Leased Premises (the "Renovations")
     shall  have  been  substantially  completed  and,  if  required,  a use and
     occupancy  permit  shall ha-,e been  issued for the Leased  Premises by the
     County.  If the  Renovations  are  performed  by  Landlord,  such  use  and
     occupancy permit, if required, shall be obtained by Landlord.

          Not   withstanding   the  provisions  of  the  immediately   preceding
     paragraph,  the parties hereby agree that if Landlord is hired by Tenant to
     perform the  Renovations  and Landlord,  for reasons  within its reasonable
     control,  fails to substantially  complete the Renovations by the projected
     completion  date as set forth on a construction  schedule to be agreed upon
     by Landlord and Tenant in writing (the "Construction  Schedule"),  then, to
     the  extent  that  such  delay is  attributable  to  Landlord,  the date of
     December 1, 1992 set forth above shall be postponed by one (1) day for each
     day that elapses between the projected completion date (as set forth on the
     Construction Schedule) and the actual date of substantial  completion.  The
     parties hereby  specifically  acknowledge that no delay caused by Tenant or
     by any  subcontractor  specifically  requested by Tenant, or resulting from
     any other cause not within Landlord's  reasonable control, will be deemed a
     delay attributable to Landlord.

          On the  Occupancy  Date or such later date as  Landlord  may  request,
     Tenant shall promptly enter into a supplementary  written agreement in such
     form as is reasonably acceptable to Landlord and Tenant, thereby specifying
     such date.

          Notwithstanding  the Commencement Date of September 1, 1992,  Landlord
     hereby  agrees  that  Tenant  may enter the  Leased  Premises  prior to the
     Commencement Date for purposes of inspecting the Leased Premises.  Tenant's
     entry into the Leased Premises prior to the  Commencement  Date shall be at
     its own risk and  subject to the  provisions  of  Section 12 below.  Tenant
     further  agrees  that prior to  Tenant's  entry  into the Leased  Premises,
     Tenant shall provide  evidence to Landlord that the insurance  described in
     Section 9 below is in full force and effect.

     3    Use.  Landlord  and Tenant  expressly  agree that the Leased  Premises
     shall be used or occupied by Tenant for any lawful purpose, as the same may
     be  limited  by  applicable  zoning  codes  and  all  covenants  and  other
     restrictions to which the Leased Premises are subject.

          Tenant  further  warrants  that it has received and reviewed a copy of
     the covenants and restrictions  affecting the use of the Leased Premises as
     set  forth on  Exhibit  E to this  Lease,  and  agrees to abide by all such
     covenants and restrictions.

     4.   Basic Annual Rent.  Commencing  ninety (90) days after the occupancy
     Date (the "Rent  Commencement  Date",) it being  understood and agreed that
     Tenant may use and occupy the Leased Premises until ninety ( 90) days after
     the Occupancy  Date (the "Free Rent Period")  without the obligation to pay
     Basic  Annual  Rent,  Tenant  shall pay to  Landlord  during the Lease Term
     "Basic Annual Rent" in the amounts and with respect to the time periods set
     forth below.

                              Basic Annual Rent            Monthly Installment

Free Rent Period ..........         -0-                          -0-

Rent Commencement Date -
  2nd Lease Year .......... $   517,930.00$                  43,160.83

3rd - 7th Lease Years .....     653,075.00                   54,422.92

8th - 12th Lease Years ....     868,250.00                   72,354.17


Basic Annual Rent shall be payable in equal  monthly  installment,  as set forth
above, without any deductions or set-offs, and without demand, in advance on the
twenty-fifth  (25th) day of each and every month  preceding  the month for which
payment is applicable  (e.g.,  April's rent is due on or before March 25) during
the Lease Term provided, however, that if the Rent Commencement Date shall occur
on a day  other  than the  first  day of a month,  Tenant  shall pay on the Rent
Commencement  Date for the fractional  part of such month, a prorated  amount of
one month's rent.  Although  Tenant may use and enjoy the Leased Premises during
the Free Rent Period  without the  obligation  to pay Basic Annual Rent,  Tenant
shall otherwise  observe,  perform and obey all other provisions of the Lease on
its part to observer  perform and obey during such  period,  including by way of
example, payments of all sums deemed additional rent, except that Landlord shall
pay all Taxes and  Insurance  applicable  to the Leased  Premises for the period
prior to the Occupancy Date.

          4.1. Definitions  - .  For  purposes  of  this  Lease,  the  following
          meanings or definitions shall apply
         
               (a)  "Rentable  Area  of the  Leased  Premises:  shall,  for  all
               purposes of this Lease,  be deemed to be an agreed  75,500 square
               feet.  Tenant  shall have the right to review the square  footage
               calculation of Landlord's architect or engineer and/or to perform
               a field measurement to verify the same, but the Basic Annual Rent
               shall in no event be  adjusted  if Tenant  determines  the actual
               square footage of the Building to be different from 75,500.
                 
               (b)  "Taxes"  shall mean any  present or future  federal,  state,
               municipal, local and/or any other taxes (including gross receipts
               or business license taxes), assessments,  levies, benefit charges
               and/or  other  governmental  or  private  impositions  (including
               business park charges and dues) , levied,  assessed and/or agreed
               to be imposed upon the Real Property or any part or parts of said
               Real  Property,  or upon  the  rent  due and  payable  hereunder,
               whether or not now customary or within the  contemplation  of the
               parties  hereto  and  regardless  of  whether  the same  shall be
               extraordinary  or  ordinary,  general  or  special,  foreseen  or
               unforeseen,  or  similar  to any of the  foregoing  but shall not
               include any  inheritance,  estate,  succession,  income,  excise,
               capital,  profits or franchise tax, provided,  however, if at any
               time during the Lease Term or any extension thereof the method of
               taxation  prevailing  at the  commencement  of the term  shall be
               altered or eliminated so as to cause the whole or any part of the
               items listed in the first  sentence of this  subsection (b) to be
               replaced by a levy, assessment or imposition, wholly or partly as
               a capital levy, or  otherwise,  on the rents or income  (provided
               the tax on such  income  is not a tax  levied on  taxable  income
               generally)  received from the Real Property,  wholly or partly in
               place of an imposition on or as a substitute for, or in place of,
               taxes in the nature of real estate taxes issued  against the Real
               Property, then the charge to Landlord resulting from such altered
               or  replacement  method of taxation  shall be deemed to be within
               the definition of "Taxes".  All reasonable  expenses  incurred by
               Landlord (including attorneys,  fees and costs) in contesting any
               increase in the assessment of the Real Property shall be included
               as an item of Taxes for the purpose of computing  additional rent
               due hereunder.

               (c)  "Real Property"  shall mean the Land, the Building,  and all
               fixtures,  equipment and _____________ upon said Land, which have
               been  provided by the Landlord and shall  include the  sidewalks,
               areaways,  parking areas, loading areas, gardens and lawns of the
               Leased Premises.

               (d)  "Insurance" shall mean insurance covering the Building,  the
               Real Property, and the equipment, fixtures and other improvements
               installed  and/or owned by Landlord and used in  connection  with
               the Building  and/or the Real  Property  and/or all  alterations,
               rebuilding,  replacement and additions thereto, insuring the same
               against loss or damage by fire,  vandalism,  malicious  mischief,
               sprinkler  leakage  (if  sprinklered)  and  such  other  hazards,
               casualties,  risks and  contingencies  not covered by or that may
               hereafter  be  considered  as  included   within,   the  standard
               all-perils,  casualty  insurance policy.  Insurance shall include
               insurance for loss of rent for one (1) year arising out of any of
               the  occurrences   covered  by  such  insurance.   Such  casualty
               insurance  shall be  carried  in an amount at least  equal to the
               Full Insurable  Value thereof.  The term 'Full  Insurable  Value,
               shall mean actual replacement costs of the Building (exclusive of
               the  costs of  excavation,  foundations  and  footings  below the
               lowest basement  floor).  It shall be the obligation of Tenant at
               Tenant's expense to have such "Full Insurable  Value",  appraised
               annually to the end that the insurance shall be kept current
         
               (e ) "Term" or "Lease Term" shall mean the initial lease term and
               a11 renewals or extensions thereof.

               (f)  "Deed of  Trust"  shall  mean the deed of trust or  mortgage
               securing Landlord's original, interim, and/or permanent financing
               for the Leased  Premises.  

          4.2.  Rent  Adjustment  -Taxes.   Tenant  shall  pay  to  Landlord  as
          additional  rent the  dollar  amount of all Taxes  levied or  assessed
          during the Lease Term  beginning on the  Occupancy  Date,  against the
          Land, the Building, or the Leased Premises. Landlord shall give Tenant
          prompt  notice of any  proposed  increase in Taxes and Tenant shall be
          entitled,  at  its  on  expense,  and  through  its  own  counsel,  to
          participate  with Landlord or  independently  to contest or oppose any
          such  increase.  Landlord  shall  cooperate  with  Tenant  as  may  be
          reasonably  required  in  any  such  contest.  All  refunds  of  Taxes
          attributable  to the  Lease  Term and  which  have been paid by Tenant
          shall belong to Tenant.  As of the date of this Lease, the tax year is
          a fiscal year commencing July 1. If the appropriate  authorities shall
          hereafter  change the tax year to a calendar year, or to a fiscal year
          commencing on a date other than July 1, appropriate  adjustments shall
          be made in the computation of any additional rent due hereunder.

          4.3.  Insurance.  Throughout the Lease Term beginning on the Occupancy
          Date,  Tenant  shall  obtain  on  behalf  of  Landlord  the  Insurance
          described  in  Section  4.1(d)  and shall  promptly  furnish a copy or
          certificate  of  same to  Landlord.  Until  the  Occupancy  Date,  the
          Insurance described in Section 4.1(d) shall be maintained by Landlord,
          at its sole cost and expense.

               Tenant  covenant s to obtain and keep the Insurance in full force
          and effect  during the Lease Term,  with a duly licensed and reputable
          insurance  company  with a rating at least  equal to that  customarily
          required  by  reputable  institutional  type  first  mortgagees.  Both
          parties  shall be named as  insureds  under the policy  providing  the
          Insurance  as  their  respective  interests  may  appear.  The  policy
          providing the Insurance shall require payment of the premium  therefor
          not more frequently than  semi-annually and shall provide for at least
          thirty (30) days prior written  notice to the insureds in the event of
          modification  or  cancellation  of  such  policy.   A  certificate  of
          insurance   shall  be  _______  to  Landlord  at  the   inception   of
          ___________________ thereof. Landlord and Tenant hereby mutually waive
          all claims for  recovery  from the other for any loss or damage to any
          of Landlord's  property or Tenant's  property  insured under valid and
          collectible  insurance policies to the extent of any recovery for loss
          insured  thereunder  and, to that end,  the parties  agree to a mutual
          subrogation  clause to be inserted or endorsed on each policy  setting
          forth that the insurance  shall not be  invalidated  in the event that
          the  insured  should  waive in writing  prior to any loss,  any or all
          right of recovery against the other party for any insured loss.
                
               In the event Tenant shall fail to obtain such  Insurance,  Tenant
          shall pay to Landlord,  as  additional  rent during each lease year of
          the Term in which  Tenant fails to obtain such  Insurance,  the dollar
          amount of premiums for Insurance on the Leased Premises.
            
          4.4. Utilities.  Tenant shall pay on a timely basis to the appropriate
          utility or other supplier,  all charges for gas,  steam,  electricity,
          light, heat, power, telephone,  water, metered or unmetered sprinkler,
          sewerage  and all other  utility  and  communication  services,  used,
          rendered  and/or  supplied  upon  or in  connection  with  the  Leased
          Premises  during the Lease Term.  Upon request,  Tenant shall promptly
          furnish  Landlord with copies of all paid receipts for such  utilities
          charges.  Notwithstanding  the  foregoing,  until the Occupancy  Date,
          Landlord  shall be  responsible  for  paying  utilities  up to a total
          amount of Two Thousand one Hundred Dollars  ($2,100.00) per month, and
          to the extent that the total cost of utilities in any calendar  monrkf
          (or, with respect to any partial month, the applicable  prorata share)
          during such period  exceeds such amount,  Tenant shall be  responsible
          for paying only such excess amount.
            
          4.5. Payments.  All  payments or  installments  of any rent  hereunder
          other than Basic  Annual Rent and all sums  whatsoever  due under this
          Lease   (including   reasonable   attorneys'  fees)  shall  be  deemed
          additional  rent  and  shall  be  paid  to  Landlord  at  the  address
          designated for notice to Landlord herein,  or as otherwise  designated
          by Landlord,  and if any  installment of Basic Annual Rent is not paid
          within 5 days of the date when due, it shall bear a late charge  equal
          to  Three  Hundred  Dollars  ($300-00)  for  each  day  such sum is in
          arrears,  and if any installment of additional rent is not paid within
          5 days of the date when due,  it shall  bear  interest  at the rate of
          eighteen percent (18t) per annum, for each day such sum is in arrears,
          in  consideration  of  Landlord's  additional  expense  caused by such
          failure to pay, which late charge or interest as applicable,  shall be
          payable without demand simultaneously with the rent arrearage. Time is
          of the  essence  in this  Lease  with  respect  to  Tenant's  monetary
          obligations hereunder.  Unless otherwise provided, any such additional
          rent  shall be due within  thirty  (30) days  after the  Landlord  has
          submitted a written  statement to Tenant  showing the amount due. Such
          obligations shall survive the expiration or sooner termination of this
          Lease.  Any such statements shall be accompanied by a copy of the bill
          or other invoice for such charge.
         
 5.  Requirements  of Law. Tenant shall, at the sole cost and expense of Tenant,
observe and comply with all laws,  requirements,  rules, orders,  ordinances and
regulations of any governmental, quasi-governmental entity or of the local Board
of Fire  Underwriters  applicable  to any  portion  of the Leased  Premises.  6.
Tenant's Improvements.

     (a)  Tenant  agrees  that  it  will  not   undertake   any   structural  or
     non-structural  alterations  of any of  the  improvements  ___________after
     erected  upon  the  Leased   Premises,__________   not  construct  any  new
     structures  or  improvements  upon the Leased  Premises,  without the prior
     written consent of Landlord  following  Tenant's  submission to Landlord of
     plans and specifications  with respect thereto,  which consent shall not be
     unreasonably  withheld  by Landlord  so long as such  alterations  will not
     materially  change the character of the existing  improvements or weaken or
     impair  the  structural  integrity  or  lessen  the  value of the  existing
     improvements.  In all other cases, Landlord's consent shall be given solely
     within  Landlord's  discretion.  Landlord shall approve or disapprove  such
     plans within seven (7) business  days of the date the same are submitted to
     Landlord by Tenant,  and, if not approved or  disapproved  within such time
     period,  such  plans  submitted  to  Landlord  by  Tenant  shall be  deemed
     approved.  With  respect to any major  improvements  to be  constructed  by
     Tenant, including the Renovations,  Tenant shall, initially, be required to
     submit only preliminary  plans to Landlord,  and if such preliminary  plans
     are approved by Landlord as described  above,  then  construction  drawings
     shall be  prepared  by Tenant and  submitted  to  Landlord  for  Landlord's
     review.  and approval in accordance with the foregoing  provisions prior to
     Tenant  beginning such work.  Interior  changes which are  decorative  only
     (e.g.,  repainting  and  recarpeting)  shall not require  Landlord's  prior
     consent.  Regardless of -whether  Landlord's  prior consent for any work is
     required,  Tenant  shall give  Landlord  notice of any change,  alteration,
     addition, enlargement or improvement and copies of plans and specifications
     therefor  prior  to  commencing  any work  thereon.  All work to be done by
     Tenant  to or in the  Leased  Premises  shall  be  done by  contractors  or
     mechanics  approved by  Landlord.  All work with  respect to which  neither
     Landlord  nor  Manekin  Corporation  is the  general  contractor  shall  be
     performed  under the general  supervision  of Landlord  for which  Landlord
     shall be paid a reasonable supervisory fee which, with respect to all major
     improvements  (including  the  Renovations)  , shall be equal to $80.00 for
     each hour of supervision performed by Landlord.

     (b)  Subject to the  limitations  contained in the  foregoing  Section 6(a)
     Tenant may, at any time during the term of this Lease, at Tenant's own cost
     and expense,  make or permit to be made any alteration,  change or addition
     of, in or to the Leased  Premises  or any part  thereof or any  building or
     improvement which may hereafter be erected thereon,  subject,  however,  to
     the  following  conditions,  each of  which  must  be  fully  observed  and
     performed by Tenant before the commencement of any work Whatsoever
          
          (i)  That there is no existing and  unremedied  default on the part of
          Tenant,  of  which  Tenant  has  received  notice,  under  the  terms,
          covenants and  conditions  herein on the part of Tenant to be observed
          and performed.

          (ii) That Tenant shall  covenant that the same shall be performed with
          diligence and in a first-class, workmanlike manner.

          (iii)That neither the interest of the Landlord nor the interest of the
          holder of the Deed of Trust nor the Leased  Premises  nor any building
          in or improvement  on, under,  or above the Leased Premises shall then
          be the subject of any charge , liability, claim, or lien of whatsoever
          kind or nature by reason of work undertaken by Tenant.

          (iv) That if under the provision of any insurance policies required to
          be provided and maintained  hereunder,  any consent to any alteration,
          change  or  addition  by the  insured  therein  shall be  required  to
          continue and keep such policies in full force and effect, Tenant shall
          obtain  such  consents  and pay any  premiums  or charges  that may be
          incurred therefor.

          (v)  Tenant shall covenant that in  the__________ of the then existing
          structures ________  construction of any one building,  it will comply
          wall  applicable  requirements  of the Building Code of the County and
          with all other applicable laws,  ordinances,  rules and regulations of
          all governmental  authorities having  jurisdiction  thereof and of the
          local Board of Fire Under-o or of any similar body.
         
          (vi) Tenant shall procure all necessary  permits for the alteration of
          the  then  existing  structures  and for the  construction  of the new
          improvements  and shall deliver to Landlord a certificate of occupancy
          when  required  by law,  as a  condition  precedent  to the use of the
          improvements, Tenant shall deliver to Landlord a set of the "as built"
          plans.

          (vii)Tenant shall maintain the construction site in a neat and orderly
          manner and shall be  responsible,  at its sole cost and  expense,  for
          removing all construction debris.

     (c)  All such work, other than movable furniture or trade fixtures, done by
     Tenant upon the Leased  Premises,  shall be the property of the Landlord at
     the termination of this Lease; provided, however, that Landlord may require
     Tenant to remove  all or any part of said  work at the  expiration  of this
     Lease,  in which event such removal shall be done at Tenant's sole cost and
     expense.  Tenant shall, at its sole cost and expense,  repair any damage to
     the Leased  Premises  and/or the Building  caused by such removal or by the
     removal of its  personalty.  Notwithstanding  the  foregoing,  Landlord and
     Tenant hereby agree that Landlord will make a determination  of whether any
     such  work must be  removed  by Tenant  at the time  Landlord  reviews  the
     proposed plans and  specifications  for such work,  and such  determination
     shall be binding on  Landlord  and  Tenant.  To the  extent  that  Landlord
     determines  that any offices or  laboratories  to be  constructed by Tenant
     could be used by a  subsequent  tenant and would not hinder the  Landlord's
     ability to re-lease the Building in the general marketplace for offices and
     laboratories,  Landlord will not require that the same be removed by Tenant
     upon the expiration of the Lease Term.

7.   Condition of Premises.

     (a)  Except as specifically  set forth in  subparagraph(  b) below,  Tenant
     shall at all times  during  the  Lease  Term take good care of and keep the
     Leased Premises and the improvements, fixtures, equipment and appurtenances
     therein  (including,  but not limited to,  walls,  windows,  doors,  pipes,
     plumbing,  water  and  sewer  connections,  heating  and  air  conditioning
     equipment and machinery,  and  electrical  works of the Building) , in good
     order and condition, and, at Tenant's sole cost and expense, shall make all
     necessary  repairs thereto,  which repairs shall be in quality and class at
     least equal to the  original  work.  Tenant  shall not commit or suffer any
     waste  of the  Leased  Premises  and  will  assume  responsibility  for all
     maintenance and repair, regardless of the nature, pertaining to the heating
     and/or air conditioning equipment.  Tenant further will obtain and maintain
     during  the term  hereof,  and any  extension  or renewal  thereof,  a full
     service  contract  on such  equipment  reasonably  acceptable  to  Landlord
     providing  at least the  services  specified  on  Exhibit B hereto.  At the
     expiration of the Lease Term, or at the sooner termination of this Lease as
     herein provided, Tenant shall deliver up the Leased Premises (including all
     Equipment  and  Furnishings,  except as set  forth  below) in the same good
     order  and  condition,  reasonable  wear and tear and  damage  by  casualty
     excepted,  as at the beginning of the tenancy,  broom clean and (subject to
     the provisions of the preceding  Section hereof) Tenant shall remove all of
     its property and/or property maintained and/or stored for or on the account
     of others therefrom prior to such termination.

     (b)  Notwithstanding  the  foregoing,  Landlord  hereby  acknowledges  that
     during the Lease Term,  Tenant may desire to replace  certain  items of the
     Equipment  and  Furnishings  Accordingly,  Landlord  hereby  agrees that if
     Tenant's  Cancellation  Option  (as  defined  in Rider  No. 6 below) is not
     exercised by Tenant and the time period for such exercise has expired, then
     Tenant  may  replace  any  of  the  items   comprising  the  Equipment  and
     Furnishings,  in which event neither the original Equipment and Furnishings
     nor their  replacements need be returned to Landlord upon the expiration of
     the Lease Term;  provided however,  that prior to any item or the Equipment
     and Furnishings being discarded,  it shall first be offered to Landlord and
     discarded  only after Landlord  elect.  in writing not to require Tenant to
     return the same to Landlord.  Any items of Tenant's personalty remaining in
     the Leased  Premises  after the  termination  of the Lease  shall be deemed
     abandoned by Tenant and become the sole property of Landlord.  Tenant shall
     also deliver to Landlord a  certification  from the company which regularly
     services the mechanical equipment, which certification shall be based on an
     inspection  conducted  within 30 days preceding the termination date of the
     Lease,  stating that all such systems are in good operating order and other
     wise in substantially the form attached hereto as Exhibit C.

     (c)  Landlord, at Tenant's sole cost and expense beginning on the Occupancy
     Date,  shall  maintain  the  grounds  and  the  exterior  of  the  Building
     (excluding  window  washing) , including but not limited to maintaining all
     grass and  landscaping,  maintaining  the driveways,  sidewalks and parking
     areas,  keeping the same free of ice, snow and debris,  and maintaining the
     roof and do-spouts. The cost of the foregoing shall be charged to Tenant at
     the actual cost to Landlord,  plus ten percent (10%). Landlord, at its sole
     cost and expense,  shall maintain and, as required,  replace the structural
     components of the Building  (that is, the exterior  walls and  foundation),
     and, as and to the extent  required,  shall replace the roof and repave the
     parking areas.
    
     (d)  Except as  otherwise  set forth in this Lease,  Landlord  shall not be
     required to furnish any serices or  facilities  to the Leased  Premises and
     Landlord  shall not be required to rebuild any  improvements  on the Leased
     Premises or to make any repairs,  replacements or renewals of any nature or
     description  to the Leased  Premises or any  improvement  thereon,  whether
     ordinary or  extraordinary,  foreseen  or  unforeseen,  or to maintain  the
     Leased Premises in any way.
          
     (e)  Notwithstanding the foregoing,  Tenant's maintenance obligations under
     this Lease shall commence upon Tenant's  entry into the Leased  Premises to
     begin its Renovations.
        
8.   Conduct on Premises.  Tenant shall not do, or permit anything to be done in
the Leased  Premises,  or bring or keep anything therein which will, in any way,
increase the rate of fire or other insurance  maintained on the Real Property by
Landlord, or invalidate or conflict with the fire insurance policies on the Real
Property;  obstruct or interfere with the rights of Landlord;  or interfere with
the good order of the Building. Tenant agrees that any increase in fire or other
insurance  premiums on the Real Property  and/or the contents  thereof caused by
the use or occupancy of Tenant shall,  as they occur or accrue,  be added to the
rent heretofore reserved and be paid as a part thereof;  and Landlord shall have
all the rights and remedies for the  collection  of same as are  conferred  upon
Landlord for the collection of rent provided to be paid pursuant to the terms of
this Lease.

9.  Insurance.  At all times during the Lease Term, Tenant, at its sole cost and
expense,  shall  provide  and keep in full  force and  effect a policy of public
liability and property damage insurance, naming Landlord and Manekin Coporation,
as their  interests  may appear,  as  additional  insureds,  with respect to the
__________of  Tenant in, on, within, from or connected with the Leased Premises,
pursuant to which the limits of  liability  shall be at least  $1,000,000.00  in
respect to any one occurrence,  and at least $2,000,000.00 as the combined limit
of  liability,  or in such  amounts as  Landlord  may  reasonably  reqire.  Said
insurance  policy  shall  contain a clause that the  insurer  will not cancel or
change the  insurance  without  first  giving  Landlord  thirty  (30) days prior
written notice. Said insurance policy shall be carried with an insurance company
approved  by  Landlord,  which  approval  shall not be  unreasonably  delayed or
withheld,  and a certificate of insurance  shall be delivered to Landlord at the
inception of each policy and renewal thereof.

10.  Mechanics' and Materialmen's Liens and Other Liens. Tenant shall discharge,
within ten (10) days after the date of filing,  any mechanics' or  materialmen's
liens filed against the Leased Premises (or Tenant's interest  therein),  or any
part thereof, purporting to be for work or material furnished or to be furnished
to Tenant. 11. Tenant's Failure to Perform. In the event that Tenant shall fail,
after  fifteen  (15) days  written  notice  from  Landlord,  to keep the  Leased
Premises in the state of condition and repair  required by this Lease; to do any
act;  make any  payment;  and/or  perform any term or covenant on Tenant's  part
required  under this  Lease,  Landlord  may (at its option,  but  without  being
required to do so)  immediately,  or at any time  thereafter and without notice,
perform  the same for the  account of Tenant  (including,  but not  limited  to,
entering upon the Leased  Premises upon  reasonable  prior oral notice to Tenant
and in the  presence  of an  employee  of  Tenant,  unless  such  entry is on an
emergency basis, to make repairs) . All rights given to Landlord in this Section
shall be in addition to any other right or remedy of Landlord herein contained.

12.  Loss, Damage, Iniury.

     (a)  Tenant hereby  expressly  agrees that Landlord  shall not be liable or
     responsible  in any manner for any damage or destruction to the property of
     Tenant or of any other  person or entity  and/or for injury or death to the
     person of Tenant or of any other  person or entity  directly or  indirectly
     due to any cause whatsoever other than the willful misconduct or negligence
     of Landlord, its contractors,  servants,  employees,  agents,  licensees or
     invitees.

     (b)  Tenant shall indemnify and hold harmless Landlord from and against all
     losses,  costs and  expenses,  settlement  payments (if such  settlement is
     approved by Tenant,  which approval shall not be  unreasonably  withheld or
     delayed)  and all  liabilities,  damages  and/or  fines  paid,  incurred or
     suffered  by  Landlord:  (i) by  reason  of any  breach,  violation  and/or
     nonperformance  by  Tenant  and/or  Tenant's  serants,  employees,  agents,
     licensees or invitees,  of any covenant or provision of this Lease; (ii) by
     reason  of or  arising  out of the  occupancy  or use by Tenant of the Real
     Property,  or any  part  thereof,  including  any  claim,  action,  suit or
     proceeding, threatened, instituted and/or made against Landlord arising out
     of or in connection therewith; and/or (iii) from any other cause whatsoever
     due to the  negligence,  or willful  misconduct of Tenant  and/or  Tenant's
     contractors,  servants,  employees, agents, licensees and/or invitees. This
     indemnification  by Tenant shall survive the  termination  or expiration of
     this Lease.
      
13.  Destruction--Fire or Other Casualty. In the event of partial or total
damage or destruction to the Leased  Premises by fire,  other  casualty,  or any
other cause  whatsoever,  then Tenant shall give  immediate  notice  thereof to
Landlord  and:  (a) this Lease  shall  continue in full force and effect and (b)
Landlord shall thereupon cause such damage or destruction to the Leased Premises
(excluding Tenant's trade fixtures,  moveable furniture and other personalty, to
be repaired  with  reasonable  speed at the expense of Landlord,  due  allowance
being made for reasonable  delay which may arise by reason of adjustment of logs
under  insurance  policies  on the  part  of  Landlord  and/or  Tenant,  and for
reasonable  delay on  account  of labor  troubles,  or any  other  cause  beyond
Landlord's  control,  and to the extent that the Leased  Premises  are  rendered
untenantable,   the  rent  shall  proportionately  abate.   Notwithstanding  the
foregoing,  Tenant  may  terminate  this  Lease  if the  rebuilding  period,  as
estimated  by  Landlord's   architect  within  30  days  of  the  date  of  such
destruction,  exceeds  120 days  from the  date of such  notification,  provided
Tenant gives  Landlord  written  notice of such  election  within 10 days of its
receipt of said  estimate.  If Landlord fails to deliver such estimate to Tenant
within such thirty day period,  Tenant may terminate this Lease by giving notice
to Landlord  within fifteen days after Tenant's  written  request to Landlord of
such  estimate  if either  Landlord  fails to deliver an  estimate  during  such
fifteen day period,  or  Landlord  delivers an estimate  within such time period
which states an estiated rebuilding period in excess of 120 days.

     Landlord  shall have no  obligation  to rebuild the Leased  Premises if the
reasonably  estimated  cost of repair and  reconstruction  exceeds fifty percent
(50%) of the Full Insurable Value of the Leased Premises unless: (i) on the date
of such destruction there shall be four (4) or more years remaining in the Lease
Term or (ii) within  thirty (30) days  following  the date of such  destruction,
Tenant, at its option, shall enter into an agreement with Landlord to extend the
Lease  Term  for a  period  of at least  four  (4)  years  from the date of such
destruction. If Tenant so elects to extend the Lease Term, Landlord covenants to
promptly  execute  and  deliver to Tenant a written  agreement  evidencing  such
extension.  In the event  Tenant  elects not to so extend this  Lease,  Landlord
shall have the right to either (i) waive the extension  requirement  and rebuild
the Leased  Premises as set forth above,  or (ii)  terminate the Lease by giving
notice of such election to Tenant on or before forty (40) days after the date of
such  destruction,  in which  event  Landlord  shall be  entitled  to retain all
insurance  proceeds,  except that portion of such insurance proceeds  reasonably
attributable  to any item on or within the Leased  Premises  which  Tenant had a
right to remove upon expiration of the Lease Term, or which item was paid for by
Tenant rather than Landlord,  it being agreed that such portion of the insurance
proceeds shall be paid promptly to Tenant.

     Any insurance proceeds made available for reconstruction shall be disbursed
in  accordance  with  the Deed of  Trust,  and,  if not held by the  beneficiary
thereof,  shall be placed in a trust escrow  account for the benefit of Landlord
and Tenant and shall be disbursed as reconstruction  proceeds. In the event that
there are  proceeds  remaining  from  payments  made  under  insurance  policies
insuring  against such damage or  destruction  - as is set forth in this Section
13, the premiums for which are paid by Tenant in accordance  with this Lease and
following the  application of such proceeds in accordance with the terms of this
Lease and/or the Deed of Trust,  such balance of proceeds shall be paid promptly
to Tenant by Landlord.

14.  Eminent Domain. If the entire Leased Premise,  shall be substantially taken
(either  temporarily  or  permanently)  for  public  purposes,  or in the  event
Landlord  shall  convey or lease the Real  Property to any public  authority  in
settlement of a threat of condemnation or taking,  the rent shall be adjusted to
the date of such taking or leasing or conveyance, and this Lease shall thereupon
terminate. If only a portion of the Leased Premises shall be so taken, leased or
condemned,  and as a result of such partial taking, Tenant is reasonably able to
use the remainder of the Leased  Premises for the purposes  intended  hereunder,
the.  this  Lease  shall not  terminate  but,  effective  as of the date of such
taking, leasing or condemnation, the rent hereunder shall be abated in an amount
thereof  proportionate  to the  area of the  Leased  Premises  _______________If
following  such partial  taking Tenant shall not be  reasonably  able to use the
remainder of the Leased Premises for the purposes intended hereunder,  then this
Lease shall terminate as if the entire Leased Premises had been taken, leased or
condemned.  In the event of a taking,  leasing or  condemnation  as described in
this Section, whether or not there is a termination hereunder, Tenant shall have
no claim  against  Landlord,  other than an  adjustment  of rent, to the.date of
taking, leasing or condemnation, and Tenant shall not be entitled to any portion
of any  amount  that  may be  regarded  as  damages  or paid as a  result  or in
settlement  of such  proceedings  or  threat.  Not  withstanding  the  foregoing
sentence,  Tenant shall be entitled to seek an award for its loss of  personalty
and relocation expenses as a result of such taking.

15.  Assigrment.  Tenant  covenants and agrees that the Leased Premises shall be
used and occupied only by Tenant or any permitted sublessees or assigns and only
for the Purpose above mentioned,  in a careful, safe and proper manner.  Tenant,
for  itself,   its  heirs,   distributees,   personal   representatives,   legal
representatives,  successors and assigns,  expressly covenants that it shall not
assign,  mortgage or encumber  this Lease,  nor  sublease,  or use or permit the
Leased  Premises  or any part  thereof to be used by others,  without  the prior
written  consent  of  Landlord  in each  instance,  which  consent  shall not be
unreasonably  withheld.  In the event that  Landlord  shall  give such  consent,
Tenant shall  nevertheless  remain  primarily liable for the terms of this Lease
and shall not be relieved from any liability Whatsoever under this Lease. Tenant
shall bear the reasonable  legal review costs incurred by Landlord in connection
with such assignment or subleasing.  Any consent by Landlord to an assignment or
subletting of this Lease shall not  constitute a waiver of the necessity of such
consent as to any subsequent  assigrment or  subletting.  Not  withstanding  the
foregoing,  Landlord  hereby  agrees that Tenant may assign this Lease or sublet
all or any portion of the Leased  Premises to Tenant's  parent company or to any
company which is wholly owned by Tenant or by Tenant's  parent company (each, an
"Affiliate")  without  any  further  consent  from  Landlord,  so long as Tenant
nevertheless remains fully liable under this Lease.
     
     In the  event  that  the  amount  of the  rent to be paid to  Tenant  by an
assignee or sublessee is greater than the rent  required to be paid by Tenant to
Landlord pursuant to this Lease, such excess shall be the property of Tenant.

     Any levy or sale in execution,  or any  assignment or sale in bankruptcy or
insolvency,  or the  appointment of a receiver or trustee of any of the property
of Tenant by a state or federal court,  shall be deemed an assignment within the
meaning of this Section.

     If this Lease be  assigned  without  Landlord's  consent,  or if the Leased
Premises or any part thereof be subleased without  Landlord's  consent,  then if
such  assignment or  subleasing is contrary to the terms of this Lease,  (i) all
expenses incurred by Landlord in connection therewith, including but not limited
to, brokerage fees, costs and expenses incurred by Landlord's agents,  servants,
independent  contractors,  and  employees,  shall be the obligation and shall be
immediately  paid by Tenant at its sole cost and  expense  upon the receipt of a
statement  therefor  from  Landlord,  and (ii)  Landlord  may,  after default by
Tenant, collect rent from the assignee,  subtenant or occupant and apply the net
amount  collected to the rent herein  reserved,  but no such collection shall be
deemed a waiver of this covenant, or the acceptance of the assignee,  subtenant,
or occupant as tenant,  or a release of Tenant from the further  observance  and
performance by Tenant of the covenants herein contained.

16.  Defaults
     
     (a)   _______________  shall be deemed a material  default by Tenant  under
     this Lease and a substantial  breach of this Lease,  entitling  Landlord to
     all remedies set forth below or existing at law or in equity:

          (1)  The filing of a petition by or against  Tenant for debtor  relief
          as defined  under the Federal  Bankruptcy  Code,  as now or  hereafter
          amended or supplemented,  or for reorganization,  arrangement or other
          rehabilitation  within  the  meaning  f the  Bankruptcy  Code,  or the
          commencement  or proceeding  for the  dissolution  or  liquidation  of
          Tenant,  whether  instituted by or against Tenant, or for the receiver
          or trustee of the  property  of Tenant,  in each case filed by a party
          other than Tenant,  if not bonded or discharged within sixty (60) days
          following  the date of filing;  for purposes of this  subsection,  the
          word  "Tenant"  shall  include any  guarantor of Tenant's  obligations
          under this Lease;
               
          (2)  The  making  by  Tenant  of an  assignment  for  the  benefit  of
          creditors  after  notice to Tenant  and a ten (10) to day  opportunity
          cure;

          (3)  The  filing  of a tax  lien in  excess  of  $50,000  against  any
          property of Tenant located within the Leased  Premises after notice to
          Tenant and a ten (10) day opportunity to cure;

          (4)  Tenant's  causing or permitting the Leased Premises to be vacant,
          the  abandonment of the Leased Premises by Tenant and/or the cessation
          by  Tenant  of  active  use of the  Leased  Premises  for the  purpose
          specified herein after notice to Tenant and a ten (10) day opportunity
          to cure, unless Tenant continues to observe all of the obligations and
          covenants on its part to perform under this Lease  (including  payment
          of Basic  Annual  Rent),  maintains  the heat  throughout  the heating
          season at no less than 50 degrees F, and  provides  adequate  security
          for the Building;


          (6)  Failure of Tenant to make payment of the basic Annual Rent herein
          reserved,  or any part thereof, or any other sum required by the terms
          of this Lease  (including  late  charges on the  foregoing as provided
          herein)  for a period  of five (5) days  after  service  of  notice by
          Landlord upon the Tenant that such payment is due (provided,  however,
          that Tenant shall be entitled to such notice and  opportunity  to cure
          only two times in any twelve month  period,  and for the  remainder of
          such 12 month period,  Tenant shall be in default for  non-payment  of
          rent if any such payment is not made when due);

          (7)  A breach by Tenant in the performance of any other term, covenant
          agreement  or  condition  of this  Lease,  on the part of Tenant to be
          performed, for a period of thirty (30) days after service of notice by
          the  Landlord  upon the  Tenant,  unless  cure of such  default  shall
          reasonably  require a longer  period  of time and  Tenant  shall  have
          commenced  such cure during  such  thirty  (30) day period,  and shall
          thereafter diligently prosecute such cure to completion.


               (b)  All rights and remedies of Landlord in this Lease enumerated
               shall be  cumulative,  and none shall  exclude any other right or
               remedy,  now or  hereafter  allowed  by or  available  under  any
               statute,  ordinance,  rule of court, or the common law, either at
               law or in equity or both. For the purposes of any suit brought or
               based  hereon,  this Lease shall be  construed  to be a divisible
               contract, to the end that successive actions may be maintained on
               this Lease as successive  periodic  sums shall mature  hereunder.
               The failure of Landlord to insist,  in any one or more  instances
               upon a strict  performance  of any of the  covenants,  terms  and
               conditions  of this  Lease,  or to  exercise  any right or option
               herein  contained,  shall  not be  construed  as a  waiver,  or ,
               relinquishment for the future, of such covenant,  term, condition
               right or option, but_____________ remain in full force and effect
               unless the  contrary is  expressed  by  Landlord in writing.  The
               receipt by Landlord of rent,  with knowledge of the breach of any
               covenant  hereof,  shall not be deemed a -waiver of such  breach,
               and no waiver by Landlord of any provision hereof shall be deemed
               to have been made  unless  expressed  in  writing  and  signed by
               Landlord.

               (c)  In the event of a default of the nature set above,  Landlord
               may,  at  any  time  thereafter,  at its  forth  in  16(a)  above
               election,  without  further notice to Tenant,  terminate this and
               Tenant's  right to  possession of the Leased  Premises,  and take
               possession  of  the  Leased  Premises,  and  remove  Tenant,  any
               occupant and any property  therefrom,  without  relinquishing any
               rights of Landlord against Tenant.

               (d)  If Tenant  breaches  this Lease as set forth  above,  Tenant
               shall be obligated to, and shall pay to Landlord a. damages, upon
               demand  and  Landlord  shall be  entitled  to recover of and from
               Tenant 'at the  election of Landlord,  all expenses  ,which shall
               have been  incurred  as a result of such  breach,  including  the
               costs of any proceedings which shall have been necessary in order
               for Landlord to recover possession of the Leased Premises and the
               expenses of rerenting  the Leased  Premises  (including,  but not
               limited  to, any  commissions  paid to any real  estate  agent in
               connection  therewith and actual  attorneys' fees incurred at the
               standard hourly rates for such attorneys); plus, if this Lease is
               terminated, either:

                    (1)  liquidated  damages, in an amount which, at the time of
                    such  termination  is  equal  to the  installments  of Basic
                    Annual Rent and the aggregate of all sums payable  hereunder
                    as additional  rental ( the '"Additional  Rental") (for such
                    purpose  considering  the annual  amount of such  Additional
                    Rental to be equal to the amount  thereof  paid in the lease
                    year or annualized  portion  thereof  immediately  preceding
                    such default) reserved hereunder, for the period which would
                    otherwise have constituted the unexpired portion of the then
                    current term of this Lease,  said amount to be discounted at
                    the rate for U.S. Treasury Bills whose term is approximately
                    of the same duration as the unexpired term of this Lease; or

                    (2)  damages (payable in monthly  installments,  in advance,
                    on the  first  day of each  calendar  month  following  such
                    termination and continuing  until the date originally  fixed
                    herein for the  expiration  of the then current term of this
                    Lease) in an amount or  amounts  equal to the sum of (i) the
                    aggregate  expenses (other than  Additional  Rental) paid by
                    LandLord  during  the  month   immediately   preceding  such
                    calendar  month for all such  items as, by the terms of this
                    Lease,  are  required  to be paid by  Tenant,  plus  (ii) an
                    amount  equal  to the  amount  of the  installment  of Basic
                    Annual  Rent  which  would  have  been   payable  by  Tenant
                    hereunder in respect of such  calendar  month had this Lease
                    and the  Lease  Term not been so  terminated,  and (iii) the
                    monthly  average  of the  Additional  Rental  payable in the
                    lease  year  or  annualized   portion  thereof   immediately
                    preceding  such  default,  over the rents,  if any, in fact,
                    collected  by  Landlord  in respect of such  calendar  month
                    pursuant to either rerenting, or from any existing permitted
                    subleases,  and any suit,  action or  proceeding  brought to
                    collect the amount of the  deficiency for any calendar month
                    shall not  prejudice  in any way the rights of  Landlord  to
                    collect the deficiency for any subsequent month by a similar
                    proceeding.

          (e)  No act or  thing  done  by  Landlord  shall  be  deemed  to be an
          acceptance  of a surrender  of the Leased  Premises,  unless  Landlord
          shal1  execute  a  written  release  of  Tenant.   Tenant's  liability
          hereunder  sha11 not be  terminated by the execution of a new lease of
          the Leased  Premises by Landlord,  regardless  of the term of such new
          lease.  Separate  actions may be maintained  each  ___________________
          against  Tenant to recover the damages due without  waiting  until the
          end of the Term of his Lease to determine the aggregate amount of such
          damages.

17.  Acceptance of Leased  Premises.  Tenant's  occupancy of the Leased Premises
shall constitute acceptance thereof as complying with all requirements of Tenant
and Landlord with respect to the condition,  order and repair thereof; provided,
however, that if the Renovations are performed by Landlord,  then the same shall
be  subject  to a  punch-list  to be  scheduled  by  Landlord  and  Tenant  upon
substantial  completion of the Renovations,  but prior to Tenant's move-in,  and
latent  defects in such  construction  of which  Tenant gives  Landlord  written
notice  within  one (1)  year  after  the  date on  which  the  Renovations  are
substantially completed.


18.  Access to Premises and Change in Services.  Landlord  and/or the authorized
representative  of Landlord or any  mortgagee or deed of trust holder shall have
the right  without  abatement  of rent,  to enter  the  Leased  Premises  at any
reasonable  hour (except in  emergencies)  to examine the examine and/or to make
such repairs  improvements  and  alterations as Landlord  and/or such authorized
representative  shall deem  necessary (but Landlord shall not be obligated to do
so) for the safety and preservation of the Building, or for any other reasonable
purpose  whatsoever,  including  exhibiting  the Leased  Premises to prospective
tenants or purchasers. Tenant shall have access to the Leased Premises seven (7)
days a week, twenty-four (24) hours a day throughout the Lease Term.

19.  Estoppel Certificates.  Each party agrees at any time and from time to time
upon not less than five (5)  business  days prior  notice by the other  party to
execute,  acknowledge and deliver to the requesting party a statement in writing
certifying  that this  Lease is  unmodified  and in full force and effect (or if
there  have been  modifications,  that the same is in full  force and  effect as
modified  and  stating  the  modifications)  and the dates to which the rent and
other charges have been paid in advance,  if any, and stating whether or not, to
the best knowledge of the signer of such certificate, the requesting party is in
breach and/or  default in  performance  of any covenant,  agreement or condition
contained in this Lease and, if so,  specifying  each such breach and/or default
of which  the  signer  may have  knowledge,  and any  other  matters  reasonably
requested in such estoppel certificate,  it being intended that a such statement
delivered hereunder may be relied upon by any party not a party to this Lease.

20.  Subordination.  Subject to Tenant's receipt of a so called  non-disturbance
agreement, from Landlord's lender, ground lessor, and any other person or entity
having an interest in the Real Property, each in a form reasonably acceptable to
Tenant and Landlord's lender, ground lessor or any other person or entity having
an interest in the Real Property, as the case may be, Tenant accepts this Lease,
and the tenancy created hereunder, subject and subordinate to any ground leases,
security interests,  mortgages,  deeds of trust or other financing  arrangements
now or  hereafter a lien upon or  affecting  the Leased  Premises or any part or
parts  thereof  and to  any  extensions,  modifications  or  amendments  thereof
(collectively,  the  'Liens')  . As to all Liens  existing  of the date  hereof,
Landlord hereby agrees to obtain such  non-disturbance  agreement  within thirty
(30) days  following  the date of this Lease,  and if  Landlord  fails to do so,
Tenant may terminate  this Lease by so notifying  Landlord  within five (5) days
after  the  expiration  of such  thirty  (30) day  period.  Notwithstanding  any
language in this Lease to the contrary,  Tenant may not begin its Renovations in
the Leased Premises until the  non-disturbance  agreement has been obtained,  or
the date by which  Tenant is entitled to terminate  the Lease as  aforesaid  has
expired.  Tenant  shall,  at  any  time  hereafter,  on  request,   execute  any
instruments  which may be necessary  to  subordinate,  or render prior  Tenant's
interest  hereunder  to such lien and the  failure of Tenant to execute any such
instruments _______ default hereunder.

21.  Attornment.  Tenant agrees that upon any termination of Landlord's interest
in the Leased  Premises  Tenant  shall,  upon  request,  attorn to the person or
entity  then  holding  title  to the  reversion  of  the  Leased  Premises  (the
'Successor')  and to all  subsequent  Successors  (provided  that such Successor
enters into a non-disturbance  agreement in form reasonably acceptable to Tenant
and the  Successor)  and shall pay to the  Successor  all rents and other monies
required  to be paid by the  Tenant,  hereunder  and  perform  all of the  other
covenants,  agreements,  provisions,  conditions,  obligations  and/or duties of
Tenant in this Lease contained.

22.  Notices. All notices,  demands and requests required under this Lease shall
be in writing and shall be mailed by United States registered or certified mail,
return  receipt  requested,  postage  prepaid,  or by  Federal  Express or other
nationally  recognized  overnight  courier  service,  or  hand-delivered  with a
receipt and addressed (i) if to Landlord, c/o Manekin Corporation, 7165 Columbia
Gateway Drive,  Columbia,  Maryland 21046, Attn: General Counsel, with a copy to
Ann Clary  Gordon,  Esquire,  c/o Shapiro and  Olander,  36 S.  Charles  Street,
Baltimore,  Maryland 21201 or (ii) if to Tenant, at the Leased Premises,  with a
copy to Donald P.  McPherson,  III,  c/o Piper  and  Marbury,  36 South  Charles
Street, Baltimore, Maryland 21201. All notices delivered in the foregoing manner
shall be deemed delivered on the date the return receipt is executed or the date
the  recipient  refuses  delivery.  Notwithstanding  the  foregoing,  all rental
payments  and other  charges due under this Lease shall be delivered to Landlord
at the address of Landlord set forth above, Attn: Accounting Department.  Either
party may designate a change of address by written notice to the other party.

23.  Landlord's Liability.  The term 'Landlord, as used in this Lease means only
the owner,  the  mortgagee,  or the trustee or the  beneficiary  under a deed of
trust,  as the case may be, for the time being, of the Building (or the owner of
a lease  of the  Building),  so that in the  event of any  transfer  of title to
Landlord's estate and interest in the Leased Premises,  the transferring  entity
shall be and  hereby  is  entirely  freed  and  relieved  of all  covenants  and
obligations of Landlord  hereunder  thereafter  accruing.  It is understood that
Landlord  on the date  hereof is a  Maryland  limiter  partnership,  and that no
partner,  general or  limited,  of said  limited  partnership,  as it may no- or
hereafter be constituted, shall have any personal liability to Tenant and/or any
person or entity claiming  under,  by or through Tenant upon any action,  claim,
suit or demand  brought  under or pursuant to the terms and  conditions  of this
Lease  and/or  arising  out of the use or  occupancy  by  Tenant  of the  Leased
Premises,  other  than  to the  extent  of  Landlord's  interest  in the  Leased
Premises.

24.  Separability, Enforceability. If any term or provision of this Lease or the
application  thereof to any person or  circumstances  shall,  to any extent,  be
invalid or unenforceable, the remainder of this Lease or the application of such
term or provision to persons or circumstances other than those as to which it is
held invalid or unenforceable,  shall not be affected thereby, and each term and
provision  of this Lease shall be valid and  enforceable  to the fullest  extent
permitted by law. Notwithstanding any language in this Lease to the contrary, if
the  Occupancy  Date does not occur on or  before  July 1, 199 3 for any  reason
within Landlord's reasonable control,  this Lease shall terminate  automatically
and neither party shall have any further liability to the other.

25.  Captions.  All headings  anywhere  contained in this Lease are intended for
convenience  of reference only and are not to be deemed or taken as a summary of
the provisions to which they pertain or as a construction thereof.

26.  Recordation.  Tenant  covenants  that  if at  any  time  any  mortgagee  of
Landlord's  interest in the Leased Premises,  any trustee or beneficiary under a
deed of trust  constituting  a lien  upon the  Building  of which  deed of trust
Landlord is grantor,  or a landlord of Landlord in respect of the real  property
upon which the Building is situate, shall require the recordation of this Lease,
or if the recordation of this Lease shall be required by any valid  governmental
order, or if any governmental  authority having jurisdiction in the matter shall
assess and be entitled  collect  transfer taxes or documentary  stamp taxes,  or
both such taxes on this Lease, Tenant shall execute such acknowledgements as may
be  necessary to effect such  recordation  and  whichever  party  requires  such
recordation  shall pay all recording fees,  transfer taxes and documentary stamp
taxes payable on, or in connection with, this Lease or such recordation.

27.  Successors and Assigns. The covenants,  conditions and agreements contained
in this Lease shall bind and inure to the benefit of  Landlord  and Tenant,  and
their respective  heirs,  distributes,  executors,  administrators,  successors,
personal and legal representatives and their permitted assigns.

28.  Waiver of Jury Trial. Landlord and Tenant desire a prompt resolution of any
litigation  between them with respect to this Lease.  To that end,  Landlord and
Tenant waive trial by jury in any action,  suit,  proceeding and/or counterclaim
brought by either against the other on any matters  whatsoever arising out of or
in any way connected with this Lease,  the  relationship of Landlord and Tenant,
Tenant's use or occupancy of the Leased Premises,  any claim of injury or damage
and/or  any  statutory  remedy.  This  waiver is  knowingly,  intentionally  and
voluntarily made by Tenant.  Tenant  acknowledges  that neither Landlord nor any
person  acting on behalf of  Landlord  has made any  representations  of fact to
induce  this  waiver  of trial by jury or in any way to modify  or  nullify  its
effect. Tenant further acknowledges that it has been represented (or has had the
opportunity  to be  represented)  in the signing of this Lease and the making of
this waiver by  independent  legal  counsel,  selected of its own free will, and
that it has had the  opportunity  to discuss  this waiver with  counsel.  Tenant
further   acknowledges  that  it  has  read  and  understands  the  meaning  and
ramifications of this waiver of jury trial.

29.  Miscellaneous.

     (a)  As used in this Lease:  (1) the  masculine  shall be deemed to include
     the  feminine  and neuter and  vice-versa;  and (2) the  singular  shall be
     deemed to include the plural and vice-versa.

     (b)  This Lease was made in the State of Maryland  and shall be governed by
     and construed in all respects in  accordance  with the laws of the State of
     Maryland.


     (c)  Tenant  covenants  and agrees that it shall not  inscribe,  affix,  or
     otherwise  display signs,  advertisements or notices in, on, upon or behind
     any  windows or on any door,  partition  or other part of the  interior  or
     exterior  of the  Building  without the prior  written  consent of Landlord
     which  consent  shall not be  unreasonably  withheld  or  delayed.  If such
     consent be given by Landlord, any such sign, advertisement, or notice shall
     be  inscribed,  painted or affixed by  Landlord,  or a company  approved by
     Landlord,  but the cost of the  same  shall  be  charged  to and be paid by
     Tenant,   and  Tenant  agrees  to  pay  the  same   promptly,   on  demand.
     Notwithstanding the foregoing, Landlord hereby agrees that Tenant will have
     the right, at its sole cost and expense,  to display an identification sign
     on the Building.  Such sign shall comply with all applicable  building code
     and zoning  requirements,  as well as all covenants and other  restrictions
     affecting the Leased Premises.

     (d)  Tenant  _________  agree  that is shall not  attach or place  awnings,
     antennas or other  projections to -he outside walls or any exterior portion
     of the  Building  nor shall any  curtains,  blinds,  shades or  screens  be
     attached to or hung in, or used in connection  with,  any window or door of
     the Leased Premises  without the prior written  consent of Landlord,  which
     consent shall not be unreasonably withheld or delayed.

     (e)  Tenant,  Tenant's  servants,   agents,   invitees,   employees  and/or
     licensees shall not park on, store on, or otherwise  utilize any parking or
     loading areas on the Real Property, except as shown on Exhibit A.

     (f)  Except as otherwise specifically provided in this Lease, no abatement,
     refund,  offset,   diminution  or  reduction  of  rent,  charges  or  other
     compensation  shall be  claimed  by or  allowed  to  Tenant,  or any person
     claiming  under it,  under any  circumstances,  whether for  inconvenience,
     discomfort, interruption of business, or otherwise, arising from the making
     of alterations, changes, additions, improvements or repairs to the Building
     or the Leased Premises, by virtue or because of any present or future
     governmental laws, ordinances, or for any other cause or reason.

     (g)  Landlord  covenants  and  agrees  that,  upon the  payment of the rent
     herein  provided  and the  performance  by  Tenant  of all  the  covenants,
     agreements and provisions hereof on Tenant's part to be kept and performed,
     Tenant  shall  have,  hold and enjoy  the  Leased  Premises,  free from any
     interference whatsoever by, from or through Landlord or anyone claiming by,
     from or through  Landlord,  except as may be otherwise  expressly  provided
     herein.

30.  Environmental Assurances. 

      (a) Covenants.  Tenant covenants with Landlord:

          (1)  that  it  shall  not  Generate  (as  defined   below)   Hazardous
          Substances  (as  defined  below)  at, to or from the  Leased  Premises
          except as specifically set forth on the 1991 Hazardous Waste Report to
          the U.S. Environmental  Protection Agency, a copy of which is attached
          to this  Lease as  Exhibit  D,  and any  other  materials  used in the
          research,  development  or production of  agricultural  biologicals or
          generated  in  connection  with  the  normal  operations  of  Tenant's
          business and only in compliance with all governmental requirements;

          (2)  to comply with all  obligations  imposed by  applicable  law, and
          regulations  promulgated  thereunder,  and all other  restrictions and
          regulations upon the Generation of Hazardous Substances at, to or from
          the Leased Premises;

          (3)  to deliver  promptly to Landlord true and complete  copies of all
          notices  received  by  Tenant  from any  governmental  authority  with
          respect to the Generation by Tenant of Hazardous  Substances  (whether
          or not at, to or from the Leased Premises);

          (4)  to complete  fully,  truthfully  and promptly any  questionnaires
          sent by Landlord  with respect to Tenant's use of the Leased  Premises
          and Generation of Hazardous Substances;


          (5)  to  permit  entry  onto  the  Leased   Premises  by  Landlord  or
          Landlord's  representatives  at any  reasonable  time  to  verify  and
          monitor Tenant's compliance with its  representations,  warranties and
          covenants set forth in this Section;

          (6)  to pay to Landlord,  as additional  rent,  the costs  incurred by
          Landlord  hereunder,  including  the  costs  of  such  monitoring  and
          verification; and

          (7)  to furnish to Landlord, at the expiration of the Lease Term or at
          the  sooner  termination  of the  ease  Term  as  herein  provided,  a
          certification to Landlord,  equivalent to that provided by Landlord in
          Section 30 (e) , from an environmental - I audit company acceptable to
          Landlord to the effect  that,  based upon an  inspection  conducted by
          such environmental  audit company not more than thirty (30) days prior
          to the  expiration  or  termination  of the Lease  Terrn,  the  Leased
          Premises are free from Hazardous Substances.

     (b)  Tenant's  Indemnification.  Tenant  agrees  to  indemnify  and  defend
     Landlord  (with legal counsel  reasonably  acceptable to Landlord) from and
     against  any costs,  fees,  or  expenses  (including,  without  limitation,
     environmental  assessment,   investigation  and  environmental  remediation
     expenses,  third party  claims and  environmental  impairment  expenses and
     reasonable attorneys' fees and expenses) incurred by Landlord in connection
     with Tenant's Generation of Hazardous  Substances at, to or from the Leased
     Premises  or in  connection  with  Tenant's  failure  to  comply  with  its
     representations,  warranties and, covenants set forth in this Section. This
     indemnification  by Tenant will remain in effect after the  termination  or
     expiration of this Lease.

     (c)  Definitions.  The term "Hazardous  Substance" means (i) any "hazardous
     waste" as defined by the  Resource  Conservation  and  Recovery Act of 1976
     (42.U.S.C.  6901 et seq.),  as amended from time to time,  and  regulations
     promulgated  thereunder;  (ii) any "hazardous  substance" as defined by the
     Comprehensive  Environmental  Response,  Compensation  and Liability Act of
     1980  (42  U.S.C.  9601  et  seq.),  as  amended  from  time to  time,  and
     regulations promulgated thereunder; (iii) any "oil, petroleum products, and
     their byproducts" as defined by the Maryland Environment Code Ann. 4411 (3)
     (i) , as amended from time to time, and regulations promulgated thereunder;
     (iv) any  "controlled  hazardous  substance"  or  "hazardous  substance" as
     defined by the  Maryland  Environment  Code Ann.,  Title 7,  subtitle 2, as
     amended from time to time, and regulations promulgated thereunder;  (v) any
     "infectious waste", as defined by the Maryland Environment Code Ann. 9-227,
     as amended from time to time, and regulations promulgated thereunder;  (vi)
     any  substance  the presence of which on the Real  Property is  prohibited,
     regulated or restricted by any law or regulation similar to those set forth
     in  this  definition;  and  (vii)  any  other  substance  which  by  law or
     regulation  requires  special  handling  in its  Generation.  The  term "To
     Generate"  means to use,  collect,  generate,  store,  transport,  treat or
     dispose of.
          
     (d)  Landlord's  Indemnification.  Landlord  agrees to indemnify and defend
     Tenant  (with  legal  counsel  reasonably  acceptable  to Tenant)  from and
     against  any  costs,  fees  or  expenses  (including,  without  limitation,
     environmental  assessment,   investigation  and  environmental  remediation
     expenses,  third party  claims and  environmental  impairment  expenses and
     reasonable  attorneys' fees and expenses)  incurred by Tenant in connection
     with  Landlord's  Generation  of  Hazardous  Substances  at, to or from the
     Leased  Premises.  This  indemnification  by Landlord will remain in effect
     after the termination or expiration of this Lease.

     (e)  Landlord's  Covenant.  Landlord  hereby  agrees to  provide to Tenant,
     within thirty (30) days following the date hereof, an environmental  report
     from Law Engineering with respect to the Leased Premises (the 'Audit'),  to
     be based upon an inspection  conducted  within thirty (30) days of the date
     hereof.  If the Audit  indicates that the Leased Premises are not free from
     Hazardous  Substances,  then Landlord hereby agrees to perform any required
     remediation  in a  prompt  and  diligent  manner  in order  for the  Leased
     Premises to be certified as free from  Hazardous  Substances.  If the Audit
     indicates  that  Hazardous  Substances  are present in the Leased  Premises
     which pose a health hazard and render the Leased Premises unsafe for use by
     Tenant,  then Tenant may terminate this Lease if the same is not remediated
     by Landlord within  forty-five (45) days after the date of delivery of such
     report to Tenant.  Such termination shall be effected by delivering written
     notice to Landlord of uch _________  five (5) days after the  expiration of
     such forty-five (45) day period.

31.  Intentionally Deleted.

32.  Authority.  Tenant  warrants  to  Landlord  that  Tenant  is a  corporation
organized and -validly  existing in good standing under the laws of the State of
Delaware  and  qualified  to  transact  business  in the State of  Maryland.  In
addition,  Tenant  warrants  to  Landlord  that  this  Lease  has been  properly
authorized and executed by Tenant and is binding upon Tenant in accordance  with
its terms.  Tenant's  resident agent's name and address in the State Of Maryland
are Joseph Lutz, 5526 Hayledge Court, Columbia, Maryland 21045.

33.  Force  Majeure.  In the event that either  party hereto shall be delayed or
hindered  in or  prevented,  by reason of  weather,  strikes,  lock-outs,  labor
troubles,   inability  to  procure  materials,  failure  of  power,  restrictive
governmental laws or regulations, riots, insurrection, war, Acts of God or other
reason of a like  nature  (excluding  lack of funds)  not the fault of the party
delayed from  performing  work or doing any act required under the terms of this
Lease, then performance of such act shall be excused for the period of the delay
and the period of the performance of any such act shall be extended for a period
equivalent  to the period of such delay.  The party so delayed shall give prompt
notice  thereof to the other party.  The provisions of this Section 33 shall not
operate to excuse  Tenant from prompt  payment of rent,  additional  rent or any
other payments required by the terms of this Lease.

34.  Real Estate Broker. Landlord and Tenant warrant that no real estate brokers
other than Manekin  Corporation  and Barnes,  Morris,  Pardoe & Foster have been
employed,  caused to be employed,  or otherwise  utilized in bringing about this
Lease,  and agree to hold harmless and indemnify  each other with respect to the
foregoing  warranty.  All commissions payable to Manekin Corporation and Barnes,
Morris,  Pardoe & Foster in connection with this Lease shall be paid by Landlord
in accordance with a separate agreement.

35.  Security  Deposit.  Tenant,  contemporaneously  with the  execution of this
Lease,  shall deposit with Landlord the sum of Forty-Three  Thousand One Hundred
Sixty Dollars and Eighty-Three  Cents ($43,160.83) as a security deposit (which,
along with all interest which may accrue  thereon is hereinafter  referred to as
the 'Deposit'),  which, to the extent the same has not been applied or exhausted
pursuant to the further  terms  hereof,  shall be returned by Landlord to Tenant
following  the  expiration  of the Lease Term.  In addition to any and all other
remedies  available to Landlord under this Lease,  Landlord shall have the right
to apply the Deposit to cure any breach by Tenant of any of Tenant's obligations
or duties  pursuant to this Lease,  and Landlord shall be entitled upon any such
application of the Deposit to require Tenant  immediately to restore the same to
the dollar amount set forth in this Section.  Landlord  shall be entitled to the
full use of the  Deposit,  and shall  not be  required  to  escrow or  otherwise
segregate  the  Deposit.  The  Deposit  shall be  maintained  by  Landlord  in a
federally  insured  interest  bearing  account.   Tenant's  federal  income  tax
identification number is: 22-2380817.

36.  Holding Over. If Tenant holds  possession of the Leased  Premises after the
termination  of this Lease  without  Landlord's  written  consent,  Tenant shall
become a tenant from month to month at double the rent payable  during the final
lease year and upon all other terms herein  specified  and shall  continue to be
such tenant from month to month until such tenancy shall be terminated by either
party  giving  the other a written  notice of at least  thirty  (30) days of its
intention to terminate  such tenancy.  Nothing  contained in this Lease shall be
construed as a consent by Landlord to the  occupancy or possession of the Leased
Premises by Tenant after termination of this Lease. Upon the termination of this
Lease, Landlord shall be entitled to the benefit of all public general or public
local  laws  relating  to the speedy  recovery  of the  possession  of lands and
tenements held over by tenants, that may now or hereafter be in force.

37.  Net Lease.  It is the purpose  and intent of  Landlord  and Tenant that the
Basic Annual Rent shall be net to Landlord, so that this Lease shall yield, net,
to Landlord,  the Basic Annual Rent  specified in Section 4 hereof in each lease
year during the Term of this Lease,  and that all costs,  expenses and charges ,
of every kind and nature  relating to the Leased  Premises  (except any income,,
franchise  or  inheritance  taxes of  Landlord,  or any  payments  on account of
interest or principal  under any Deed of Trust  executed by Landlord which shall
be a lien on the Leased  Premises  and any other costs  specifically  payable by
Landlord under the terms of this Lease) which may arise or become due during the
Term of this Lease shall be paid by Tenant,  except as  otherwise  provided  for
herein and that Landlord shall be indemnified  and saved harmless by Tenant from
and against the same.

38.  Riders.  Six (6) riders  consisting of eight (8) pages are attached to this
Lease and made a part of it.

    IN WITNESS WHEREOF,  Landlord and Tenant have respectively signed this Lease
under seal as of the day and year first above written.


                                             M.O.R. XVIII ASSOCIATES LIMITED
                                             PARTNERSHIP

WITNESS/ATTEST                               BY:  RK & DM, Inc.

___________________                          BY:________________________(SEAL)
                                             Name:   Richard M. Alter
                                             Title:  President
                                                                   Landlord

                                             CROP GENETICS INTERNATIONAL
                                             CORPORATION

__________________                           By:________________________(SEAL)
                                             Name:   Joseph L. Kelly
                                             Title:  President
                                                                   Tenant



STATE OF MARYLAND, CITY/COUNTY OF______________ TO WIT:  
     I HEREBY  CERTIFY  that on this 1st day of  October,  1992,  before me, the
subscriber,  a Notary  Public  of the  State of  Maryland,  City/County  of Anne
Arundel,  personally  appeared  Richard M. Alter,  President  of RA & DM,  Inc.,
general partner of M.O.R. XVIII Associates Limited Partnership, Landlord, and he
acknowledged  the  foregoing  Lease  Agreement  to be the act  and  deed of said
limited partnership.

    WITNESS my hand and Notarial Seal.

     My Commission Expires:
                                   _________________________________________
    11-1-93                        Notary Public

<PAGE>



STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:  

     I HEREBY  CERTIFY  that on this 28th day of  August,  1992,  before me, the
subscriber,  a Notary  Public  of the  State of  Maryland,  City/County  of Anne
Arundel,   personally   appeared  Joseph  Kelly,   President  of  Corp  Genetics
International  Corporation,  Tenant,  and he  acknowledged  the foregoing  Lease
Agreement to be the act and deed of said body corporate.
   
  WITNESS my hand and Notarial Seal.

     My Commission Expires:

     ____________________________________         ___________________________
     My commission expires October 1, 1994        Notary Public

<PAGE>



                                   RIDER NO. I

                               Landlord's Consent

     Notwithstanding  what  is  otherwise  stated  herein,  whenever  Landlord's
consent is required  under this Lease,  such consent  shall not be  unreasonably
withheld, conditioned or delayed.

<PAGE>

                                   RIDER NO. 2

                                Expansion Option

     So long as this Lease is then in full force and effect and Tenant is not in
default of any  covenant or  obligation  to be  performed  by Tenant  under this
Lease,  Tenant shall have the right,  throughout  the Lease Term,  to expand the
Leased  Premises by requesting  that Landlord  increase the size of the existing
Building,  or by requesting that Landlord build a new structure or structures on
the Land. If Tenant's expansion needs cannot reasonably be met by increasing the
size of the existing  Building or by building a new  structure or  structures on
the Land, then Tenant may alternatively  request that Landlord build a structure
or structures  on the 5.3 acre parcel  adjacent to the land known as Parcel M-3,
as more  particularly  shown  on  Exhibit  A  attached  hereto  (the  'Expansion
Parcel'),  if such  Expansion  Parcel is so available.  The Expansion  Parcel is
designated  as  Parcel  M-3 on  the  Plat  entitled  'Parcels  M-2  and  M-3,  A
Resubdivision of Parcel M-1, Plat No. 51941, and recorded among the Land Records
of Howard County,  Maryland as Plat No. 5698.  Tenant's right to have the Leased
Premises  expanded as aforesaid is subject to Landlord and Tenant  agreeing upon
the terms and  conditions  upon which such  expansion  ,ill be effected.  In any
event,  the  construction  of any  improvements  upon the Land or the  Expansion
Parcel shall be subject to Landlord's  prior written  approval.  Landlord  shall
have the right to withhold such approval if, in Landlord's  reasonable judgment,
any such  expanded  area  shall  adversely  affect  the  value  of the  existing
improvements  on the Land,  or if Landlord  determines  that such  expanded area
would not be  leasable in the general  market upon the  expiration  of the Lease
Term. The parties further agree that any and all costs and expenses. arising out
of or payable in connection with any such expansion,  including, but not limited
to,  architectural,  engineering and legal fees,  petit and application  fees, a
development or supervisory  fee to Landlord,  and  acquisition  and/or  carrying
costs of the Expansion  Parcel (such  acquisition  and/or  carrying costs not to
exceed the fair market rental rate for the Expansion Parcel, determined pursuant
to the  agreement  and  appraisal  procedure  set  forth in  Rider  No.  5),  if
applicable, shall be paid by Tenant, at its sole cost and expense.

     Landlord's  obligations under this Rider No. 2 shall be subject to Landlord
obtaining the financing for such  expansion on terms which are  satisfactory  to
Landlord.

     Tenant's  expansion  option shall be further subject to compliance with all
applicable la-9,  including zoning  ordinances and other County,  state or local
restrictions,  as well as the covenants and restrictions  applicable to the Land
and the Expansion Parcel.
<PAGE>

                                   RIDER NO. 3

                              Right of First Offer

     If at any time during the term of this Lease, Landlord shall desire to sell
its leasehold  interest in the Real  Property,  Landlord  shall notify Tenant in
writing and such notice  (,Landlord's  Notice,) shall contain a statement of the
terms and  conditions  upon which  Landlord  is  willing  to sell its  leasehold
interest in the Real Property to any third party.  For a period of 30 days after
Landlord's  Notice is  given,  Tenant  shall  have the  right  and  option  (the
'Option')  to  elect  to  purchase  Landlord's  leasehold  interest  in the Real
Property upon the terms and conditions set forth in Landlord's Notice,  provided
that  Tenant  is not in  default  of the  Lease  on the date of such  Notice  of
Exercise, as hereinafter defined. Such option shall be exercised,  if at all, by
giving Landlord written notice thereof ('Notice of Exercise') within such 30-day
period and depositing with Landlord a deposit in an amount equal to five percent
(5%) of the purchase  price set forth in Landlord's  notice.  If Tenant fails to
give its Notice of Exercise  within such 30-day period,  Landlord shall have the
right,  for a period of one year after the expiration of such 30-day period,  to
sell its leasehold  interest in the Real  Property at a purchase  price which is
not less than ninety percent (90%) of the purchase price set forth in Landlord's
Notice to Tenant.  if Landlord does not sell its leasehold  interest in the Real
Property to a third party within such one year period, and subsequently  desires
to offer its  leasehold  interest in the Real  Property for sale, or if Landlord
desires to offer its leasehold interest in the Real Property at a purchase price
which is less than ninety percent (90%) of the purchase  price  contained in the
previous  Landlord's  Notice to Tenant,  Landlord  shall not sell its  leasehold
interest in the Real  Property  without  first  giving a new  Landlord's  Notice
offering  to sell its  leasehold  interest  in the Real  Property  to Tenant and
allowing Tenant thirty (30) days to accept such offer, in accordance with and as
more  specifically  set forth in the  preceding  provisions.  In the event  that
Landlord  sells its  leasehold  interest  in the Real  Property to a third party
pursuant to the  provisions of this Rider No. 3, such sale shall be made subject
to all of the terms and  conditions  of this Lease,  with the  exception of this
Rider No. 3. This Option shall not be separated from the Lease or transferred or
assigned by Tenant  independently  of the leasehold  interest  without the prior
written consent of Landlord.

     The  consummation of such purchase by Tenant (the 'Closing')  shall be held
in Baltimore,  Maryland,  at a time and place mutually agreeable to Landlord and
Tenant, but by no later than 90 days after the date of the Notice of Exercise.

     Notwithstanding  anything  in  this  Rider  No.  3 to the  contrary,  it is
specifically  understood and agreed that Tenant's option shall apply only to the
sale of  Landlord's  leasehold  interest in the Real  Property and shall have no
application  whatsoever to any transfer,  sale or assignment of any  partnership
interests in Landlord  (other than the transfer of all or  substantially  all of
such  interests) or any offer or bid by a purchaser at any sale resulting from a
foreclosure of the lien of any Deed of Trust affecting the Real Property.

     Upon the  completion  of the  purchase  under  this  Option  but not  prior
thereto,  this Lease and all obligations  hereunder (including the obligation to
pay Rent)  shall  terminate  with  respect to the Leased  Premises,  except with
respect to obligations  and  liabilities  of the parties,  actual or contingent,
under this Lease which arose on or prior to such date of purchase,  all of which
obligations and liabilities shall survive such purchase.

     If Tenant  fails or refuses to purchase or pay for  Landlord's  interest in
the Real  Property in  accordance  with and by the time  required by this Rider,
then,  Tenant shall have no further rights  whatsoever  under this Rider and the
Option  shall be  terminated,  null and void.  Landlord's  only remedy if Tenant
fails to complete the purchase  will be to retain the deposit  Tenant  deposited
with Landlord with the Notice of Exercise.

     At the time Landlord offers to sell to Tenant its leasehold interest in the
Real Property, Landlord hereby agrees to request the consent of the owner of the
Real Property's revisionary interest (the 'Fee owner') to sell such reversionary
interest  to  Tenant  in order to  effect a  simultaneous  sale to Tenant of the
leasehold  and  reversionary  interests.  In the event the Fee Owner  grants its
consent to such sale to Tenant,  the sale of the Real Property shall be upon all
of the terms and  conditions as are set forth in this Rider No. 3 except that it
shall  pertain  to the  sale of the  Real  Property  in fee  simple  so that the
purchase  price and all other terms and  conditions  will be adjusted or revised
accordingly.
<PAGE>

                                   RIDER No. 4
                             Right of First Refusal
                               (Expansion Parcel)



     Tenant shall have the right of first refusal (the 'First Refusal Right') to
lease or  purchase  the  Expansion  Parcel on the terms  and  conditions  as the
Expansion  Parcel is sought to be leased or purchased,  as the case may be, by a
bona fide prospective tenant or purchaser,  as the case may be, of the Expansion
Parcel and acceptable to Landlord (the 'Expansion Offer') . Tenant's exercise of
its First Refusal  Right shall be effective  only upon written  notification  by
Tenant to Landlord  thereof.  Such notification must be given to Landlord before
the  close  of  business  ten (10)  business  days  after  Tenant's  receipt  of
Landlord's written notification to Tenant of the Expansion Offer.

     In the event Tenant fails to so notify  Landlord within said 10 day period,
Landlord  shall  be free to lease or  sell,  as the case may be,  the  Expansion
Parcel for a period of one year after the expiration of such 10-day period, at a
rental rate or purchase price, as the case may be, which is not less than ninety
percent  (90t) of the rental  rate or  purchase  price,  as the case may be, set
forth in the Expansion  Offer.  If Landlord does not lease or sell the Expansion
Parcel within such one year period and  subsequently  receives a bona fide offer
to lease or purchase the same on terms  acceptable  to Landlord,  or if Landlord
desires  to lease or sell the  Expansion  Parcel  at a rental  rate or  purchase
price, as the case may be, which is less than ninety percent (90%) of the rental
rate or purchase price contained in the precious Expansion Offer to Tenant, then
Landlord  shall not lease or sell the  Expansion  Parcel  without first giving a
new.  Expansion Offer to Tenant and allowing Tenant 10 days to accept such offer
in  accordance  with  and as  more  specifically  set  forth  in  the  preceding
provisions.  In the event that Landlord  sells the  Expansion  Parcel to a third
party  pursuant to the  provisions  of this Rider No. 4, such sale shall be made
subject to all of the terms and conditions of this Lease,  with the exception of
this Rider No. 4.

     This  First  Refusal  Right  shall  not be  separated  from  the  Lease  or
transferred by Tenant  independently of the leasehold interest without the prior
written consent of Landlord.

     Notwithstanding  any  other  provision  hereof,  (a)  Tenant  shall  not be
entitled  to  exercise  the rights  accorded  to Tenant in the first  paragraph,
unless at the date of such exercise,  Tenant is not in default in the payment of
any sums due hereunder or any other material  obligation  imposed upon Tenant by
the Lease, and (b) this First Refusal Right shall have no application whatsoever
to any transfer,  sale or assignment  of any  partnership  interests in Landlord
(other than a transfer of all or  substantially  all of such  interests)  or any
offer or bid by a purchaser at any sale resulting from a foreclosure of the lien
of any deed of trust,  mortgage or similar  instrument  affecting  the Expansion
Parcel.

     Landlord hereby agrees to execute a Memorandum-  for recordation  among the
Land Records of Howard  County,  Maryland for purposes of confirming  the rights
granted to Tenant  pursuant to this Rider No. 4, and Tenant's  expansion  rights
respecting  the  Expansion  Parcel  pursuant  to  Rider  No.  2, so long as such
Memorandum  is  prepared  by Tenant  and  acceptable  in form and  substance  to
Landlord and Landlord's  counsel,  Tenant pays all recording  costs and transfer
and  documentary  taxes,  if any,  arising  out of such  recordation,  and  such
recording is consented to in advance by Landlord's lender.
<PAGE>

                                   RIDER NO. 5
                                 Renewal Option

     A. Provided (i) this Lease is then in full force and effect, (ii) Tenant is
not in default of any  monetary  obligation  under this Lease either on the date
Tenant  elects to renew or on the date the renewal term  commences,  then Tenant
shall have the right to renew this Lease with  respect to all, and not less than
all,  of the space then leased by Tenant  under this Lease,  for two (2) renewal
terms of five (5)' years each (the 'Renewal  Terms')  immediately  following the
expiration  of the original term and the first renewal term, as the case may be,
on the same terms,  conditions,  and provision.  a-, are set forth in this Lease
with the same force and effect as though this Lease had originally  provided for
an approximately seventeen (17) or twenty-two (22) year term, save that:

          (i) there  shall be no  further  right of  renewal,  after the  second
     Renewal Term; and

          (ii) the Basic Annual Rent  payable  during each Renewal Term shall be
     increased to  ninety-five,  percent  (95t) of the  prevailing  'Fair Market
     Rental  Rate,  (as  hereinafter  defined)  as of  the  commencement  of the
     applicable  Renewal  Term,  but in no event  shall  the Basic  Annual  Rent
     payable by Tenant  during each  Renewal  Term be less than the Basic Annual
     Rent payable by Tenant (on a per square foot basis) during the  immediately
     preceding lease year.

     B. 'Fair Market  Rental  Rate' shall be the amount  agreed upon by Landlord
and  Tenant as the then  prevailing  market  rent for  Class A office  space for
comparable  buildings in the Columbia,  Maryland  office market.  If the parties
fail to reach  agreement  as to the Fair Market  Rental Rate within  thirty (30)
days after Tenant  exercises its renewal option,  then 'Fair Market Rental Rate'
shall be determined by an appraisal conducted as follows:

          Within five (5) business  days after the  expiration  of the aforesaid
     thirty (30) day period,  Landlord and Tenant  shall give written  notice to
     the  other  that  each,  at its own  expense,  has hired  and  appointed  a
     disinterested person of recognized  competence and professional  experience
     as an appraiser of comparable  commercial and industrial real estate in the
     Baltimore-Washington  Metropolitan  Area. The two appraisers thus appointed
     shall mutually agree upon the appointment of a third appraiser, the cost of
     which shall be shared equally by Landlord and Tenant, which appraiser shall
     also be a disinterested  person of recognized  competence and  professional
     experience as an appraiser of comparable  commercial  and  industrial  real
     estate  in  the  Baltimore-Washington  Metropolitan  Area.  Each  appraiser
     appointed pursuant to this Rider shall bear the designation of title "MAI".
     In the event that the two appraisers  shall be unable to agree,  within ten
     (10)  days  after  their  appointment,  on the  appointment  of  the  third
     appraiser,  then Tenant shall choose three  appraisers  from whom  Landlord
     shall  choose one who shall serve as the third  appraiser.  Landlord  shall
     notify Tenant of the selection of the third appraiser  within ten (10) days
     of Tenant's  notice to Landlord of the  selection of such three  appraisers
     from which Landlord is to choose.  The third appraiser shall as promptly as
     possible,  but in no event more than thirty (30) days after the date of his
     selection,  conduct an  appraisal  of the Leased  Premises  for purposes of
     __________  the then 'Fair Market Rental  Rate'.  Landlord and Tenant shall
     each be entitled to present  evidence and argument to the third  appraiser.
     Upon completion of his appraisal,  the third  appraiser  shall  immediately
     give written notice to the parties hereto  stating his  determination,  and
     shall furnish to each party hereto a copy of such  determination  signed by
     him which determination shall be final and binding on the parties. Provided
     however,  that if such  determination  shall be  unsatisfactory  to Tenant,
     Tenant  shall have the right to withdraw  Tenant's  exercise of the renewal
     option by so notifying  Landlord  within  fifteen (15) days  following  the
     arbitrator's determination of the renewal rent, in which event Tenant shall
     promptly  reimburse  Landlord for any and all costs incurred by Landlord in
     connection with the appraisal process described above.

     C. Tenant shall be deemed to have waived the right to exercise this renewal
option unless not less than one (1) year prior to the  expiration of the Initial
Term or the first  Renewal  Term, as the case may be, Tenant shall have notified
Landlord in writing of Tenant's  election to renew (the 'Renewal Notice') . Time
is of the essence  with  respect to Tenant's  rights  under this Rider No. 2 and
Tenant  acknowledges  that Landlord requires strict adherence to the requirement
that the Renewal Notice be timely and in writing, except that the parties do not
intend that the exercise of the renewal option pass by inadvertence.  Therefore,
if Tenant does not exercise the option by the required  date,  Landlord  will so
notify  Tenant and  provide  fifteen  (15) days from the date of such notice for
Tenant to exercise such option.
<PAGE>

                                   RIDER NO. 6

                              Right of Cancellation


     Tenant shall have the right to terminate  this Lease on the last day of the
third (3rd) Lease Year (the "Cancellation Date"), provided that:

          (a)  Tenant  shall  have  given to  Landlord  written  notice  of such
     election to terminate at least one (1) year prior to the Cancellation  Date
     (the "Notice");

          (b)  Tenant,  on  the  date  Tenant  gives  such  Notice  and  on  the
     Cancellation  Date,  shall not be in breach or  default  of any  agreement,
     condition or covenant by which Tenant is obligated under this Lease;

          (c) Tenant  shall have paid to Landlord on or before the  Cancellation
     Date in  addition  to any other  amounts  that may be due under  this Lease
     prior to the  Cancellation  Date,  the  amount of Six  Hundred  Fifty-three
     Thousand  Seventy- five Dollars  ($653,075.00)  . Such amount so payable by
     Tenant  represents  liquidated  damages for terminating this Lease prior to
     the  expiration  of the original  Lease Term,  such damages not  other-wise
     being susceptible to reasonable calculation; and

          (d) On or before the  Cancellation  Date,  Tenant  returns  the Leased
     Premises  to the  condition  to which the Leased  Premises  would have been
     required  to have been  returned  upon the  expiration  of the  Lease  Term
     pursuant to the provisions of Section 6 of this Lease.

     Time is of the  essence  with  respect to  Tenant's  exercise of its rights
under  this  Rider,  and  Tenant  acknowledges  that  Landlord  requires  strict
adherence to the requirement  that the Notice be timely made and in writing.

<PAGE>
                                   Exhibit A
                             Expansion Parcel (M-3)
                                 Graphic Image
                                  See Appendix
<PAGE>




                                    EXHIBIT B

                                   HVAC SYSTEM

                            PREVENTATIVE MAINTENANCE
                                       AND
                         FULL PARTS AND LABOR SERVICING



                         MINIMUM SERVICE SPECIFICATIONS



I.  Full  Parts & Labor

     A.   The services  provided are meant to be for full parts and labor on the
          installed  equipment  as detailed on a separate  sheet.  Such  service
          shall  include  all repair.  resulting  from  malfunctions  discovered
          during inspections and emergency service requests.


     B.   Components  that may be obsolete will be repaired until such parts are
          no longer repairable and the equipment must be replaced.


II.  Inspections Shall be Provided as follows:

        A.   General: Performed at all inspections

             I.   Replace all filters as required
             2.   Lubricate all motors and bearings
             3.   Adjust and/or replace all fan belts
             4.   Clean grills, etc., as required

B.  Spring/Summer:

     I.   Check  refrigerant   charge  and/or   temperature   difference  across
          evaporator coil
     2.   Check refrigerant piping for leaks with electronic leak-detector
     3.   Check all operating and safety controls for cooling
     4.   Check system operation - (operating pressures, super heat, compressor
          running current, condensate removal, etc.)
     5.   Clean condenser and/or evaporator coil as required
     6.   Check and tighten all electrical connections at unit as required

C.    Fall/Winter:

      1.   Check system operation - (operating pressures, etc.)
      2.   Check all operating and safety controls for heating
      3.   Check and tighten all electrical connections at unit as required



                                                                       EXHIBIT B
                                                                        LANDLORD
                                                                          TENANT

<PAGE>


                                    EXHIBIT C

                          CERTIFICATION OF HVAC SYSTEM
                              BY LICENSED MECHANIC



BUILDING ADDRESS:________________________________________



TO WHOM IT MAY CONCERN:

The heating and cooling  equipment which conditions the air in the subject space
has been thoroughly inspected- All necessary repairs,  replacements, and service
have been performed to insure that the system operates properly in the following
aspects:


     1.   All electrical circuitry and all components function properly.

     2.   Refrigerant charge is correct.

     3.   Evaporator and condenser coils are clean.

     4.   Belts are in good condition and all new filters installed.

     5    All bearings are in good order and properly greased.

     6.   All wiring is in order and properly secured.

     7.   All  access  panels  are  in  place. 

     8.   All air diffusers include operational dampering devices.

     9    All oil-heating appliances are clean and properly adjusted.

     10.  Components  requiring  clear and  unobstructed  condition  for  proper
          operation are in order.

     11.  All safety devices are operational.

     12.  Thermostats are operational, calibrated, and in proper condition.


                                     NAME OF CERTIFYING CONTRACTOR:
                                     By:  (NAME OF COMPANY REPRESENTATIVE):



                                     LICENSE NO.:

                                     DATE OF CERTIFICATION:



                                                       EXHIBIT C
                                                       Landlord ______________

<PAGE>
                            Exhibit D - Page 1 of 4
                                 Graphic Image
                                  See Appendix
<PAGE>
                            Exhibit D - Page 2 of 4
                                 Graphic Image
                                  See Appendix
<PAGE>
                            Exhibit D - Page 3 of 4
                                 Graphic Image
                                  See Appendix
<PAGE>
                            Exhibit D - Page 4 of 4
                                 Graphic Image
                                  See Appendix
<PAGE>
Exhibit D - Page 1 of 12
Graphic Image 
See Appendix
<PAGE>
Exhibit D - Page 2 of 12
Graphic Image 
See Appendix
<PAGE>
Exhibit D - Page 3 of 12
Graphic Image 
See Appendix
<PAGE>

Exhibit D - Page 4 of 12
Graphic Image 
See Appendix
<PAGE>

Exhibit D - Page 5 of 12
Graphic Image 
See Appendix
<PAGE>

Exhibit D - Page 6 of 12
Graphic Image 
See Appendix
<PAGE>
Exhibit D - Page 7 of 12
Graphic Image 
See Appendix
<PAGE>
Exhibit D - Page 8 of 12
Graphic Image 
See Appendix
<PAGE>
                                
Exhibit D - Page 9 of 12
Graphic Image 
See Appendix
<PAGE>

Exhibit D - Page 10 of 12
Graphic Image 
See Appendix
<PAGE>
Exhibit D - Page 11 of 12
Graphic Image 
See Appendix
<PAGE>

Exhibit D - Page 12 of 12
Graphic Image 
See Appendix
<PAGE>

                                   Exhibit E

                           Covenants and Restrictions

     1. Subject to the terms and provisions  contained in an instrument entitled
'Deed, Agreement and Declaration' dated December 13, 1966 and recorded among the
Land Records of Howard County in Liber 463, folio 158, between The Columbia Park
and Recreation Association, Inc. and C. Aileen Ames.
       
     2. Subject to the terms and  provisions  as  contained  in  Corporate  Park
Declaration of Covenants,  Conditions and  Restrictions  recorded among the Land
Records of Howard  County in Liber 1083,  folio 392 by The Howard  Research  and
Development Corporation.
       
     3. Subject to the terms and  conditions of that certain Deed dated December
29, 1982 by and between The Howard  Research  and  Development  Corporation  and
K.O.R. XVIII Associates Limited  Partnership  recorded among the Land Records of
Howard County, Maryland in Liber 1135, folio 573.



079JC4 68.txt
41872.017:02
                                             EXHIBIT E
                                             LANDLORD__________________
                                             TENANT ___________________
<PAGE>


                                 SUBORDINATION,
                    NON-DISTURBANCE AND ATTORNMENT AGREEMENT



     THIS AGREEMENT (this 'Agreement') is made this 2nd day of October, 1992, by
and among New England Life Pension Properties; A Real Estate Limited Partnership
("NELPP"),   R.  Lawrence  Koch,  Jr.  and  Timothy  Dell,  trustees  for  NELPP
(collectively  referred  to  herein  as  the  "Trustees")  , and  Crop  Genetics
International Corporation, a Delaware corporation ('Tenant").


                             Explanatory Statement

     A. Pursuant to an Agreement of Lease dated  October 1, 1992 (the  "Lease'),
as amended by an Amendment of Lease dated October 1, 1992,  Tenant has agreed to
lease from M.O.R. XVIII Associates Limited Partnership ('Landlord') the premises
known as Parcel  M-2  located  in the Rivers  Corporate  Park in Howard  County,
Maryland and all improvements thereon (the 'Leased Premises').

     B.  NELPP is the  owner  in fee  simple  of the  "Leased  Premises  and the
beneficiary  under a Purchase Money Deed of Trust dated May 29, 1982 by Landlord
to the trustees named  therein,  as amended by a First  Modification  of Deed of
Trust dated July 1, 1983 between  Landlord and certain  trustees  named therein,
and a Second Modification of Deed of Trust dated March 28, 1984 between Landlord
and the Trustees (collectively, the 'Deed of Trust').

     C. Landlord is the leaseholder  owner of the Leased Premises pursuant to an
unrecorded  Ground  Lease dated March 28, 1984 between  NELPP and Landlord  (the
'Ground Lease").

     D. Tenant desires to receive certain assurances from NELPP and the Trustees
that Tenant's  possession of the Leased  Premises will not be disturbed by NELPP
or Trustees,  and NELPP and the Trustees are willing to grant certain assurances
upon the terms and conditions hereinafter set forth.

     NOW, THEREFORE,  for and in consideration of the Explanatory Statement, the
mutual covenants herein contained and other good and valuable consideration, the
receipt and adequacy of which are hereby acknowledged,  the parties hereby agree
as follows:


          1. Tenant  acknowledges that the Lease and all of the rights of Tenant
     thereunder  shall be and remain subject and  subordinate in all respects to
     the Ground  Lease,  the Deed of Trust and all of the  rights of NELPP,  the
     Trustees and the beneficiary under the Deed of Trust. Tenant further agrees
     that in the event NELPP or the purchaser at a foreclosure sale shall obtain
     possession of, or acquire title to,  Landlord's  leasehold  interest in the
     Leased  Premises  pursuant  to the Deed of Trust,  or in the event that the
     Ground Lease is terminated,  cancelled or surrendered,  Tenant shall attorn
     to and recognize  NELPP or the purchaser at  foreclosure  sale, as the case
     may be,  as  Tenant's  landlord  for the  balance  of the term of the Lease
     remaining  after such  possession  of or title to  Landlord  I a  leasehold
     interef3t  in the Leased  Premises is obtained  or  acquired,  or after the
     Ground Lease is terminated,  cancelled or surrendered,  as the case may be,
     in  accordance  with the terms and  provisions  of the Lease,  but  subject
     nevertheless to the provisions of this Agreement which shall be controlling
     in the  event  of any  conflict.  Immediately  upon  any  appointment  of a
     receiver  under  the Deed of  Trust or  purchase  of  Landlord's  leasehold
     interest in the Leased  Premises by NELPP or other person at a  foreclosure
     sale of the  Leased  Premises,  or upon the  termination,  cancellation  or
     surrender  of the Ground  Lease,  a. the case may be,  NELPP (or such third
     party  purchaser,  as the case may be) shall be substituted as the landlord
     under the  Lease,  and shall  perform  with  respect  to Tenant  all of the
     Landlord's obligations and duties thereafter arising under the Lease.

          2.  So long as no event of default exists, nor any event has occurred,
     which  event of default  has  continued  to exist for such  period of time,
     after notice,  if any, required by the Lease, as would entitle the Landlord
     under the Lease to terminate the Lease or would cause,  without any further
     action of the Landlord  thereunder,  the termination of the Lease,  (a) the
     Lease  shall  not be  terminated,  (b)  the  Tenant'  use,  possession  and
     enjoyment of the Leased Premises shall not be disturbed or interfered with,
     (c) and the  leasehold  estate  granted to Tenant in the Lease shall not be
     affected in any manner whatsoever by the termination of the Ground Lease or
     Deed of Trust or by any foreclosure sale or by NELPP or the Trustees taking
     any action  pursuant to their  rights set forth in the Ground Lease or Deed
     of Trust or by any purchaser at a foreclosure sale.

          3. Tenant  hereby  agrees that NELPP or any  purchaser at  foreclosure
     sale shall not be (a) liable for any act or omission of Landlord  under the
     Lease,  (b) subject to any offsets or defenses which Tenant may have at any
     time  hereafter  against  Landlord,  (c) bound by any rent which Tenant may
     have paid to Landlord for more than the current month,  or (d) bound by any
     amendment or modification of the Lease  subsequent  hereto made without the
     prior  written  consent of NELPP;  provided  that NELPP or any purchaser at
     foreclosure  sale,  as the case may be, shall  perform all  obligations  of
     Landlord  under  the Lease  beginning  as of the date the  Ground  Lease is
     terminated,  cancelled  or  surrendered,  or  NELPP  or such  purchaser  at
     foreclosure,  as the case may be,  acquires  or obtains  possession  of the
     Leased Premises.

          4. Tenant  hereby  agrees that if NELPP or a purchaser at  foreclosure
     sale at any  time  becomes  the  landlord  under  the  Lease,  NELPP or the
     purchaser at foreclosure  sale shall be liable only for the  performance of
     the  obligations  of the  Landlord  under the Lease  which arise and accrue
     after  the date on which  the  Ground  Lease is  terminated,  cancelled  or
     surrendered,  or during the period of the  possession  and/or  ownership of
     Landlord  Is  leasehold  interest  in the Leased  Premises  by NELPP or the
     purchaser at foreclosure sale, as the case may be.
               
          5. Tenant agrees, thirty (30) days before exercising any of its rights
     and remedies under the Lease (other than giving required notice to Landlord
     pursuant thereto) in the event of Landlord's  default  thereunder,  to send
     written notice to NELPP, c/o Copley Properties Company,  Inc., 399 Boylston
     Street,  Boston,  Massachusetts  02117, by certified  mail,  return receipt
     requested, of the occurrence of any default by Landlord under the terms and
     provisions of said Lease,  specifying  with  reasonable  clarity the events
     constituting  such default,  and NELPP shall have the opportunity,  but not
     the obligation, to cure such default.

          6. Tenant  hereby  acknowledges  and warrants to NELPP that it has not
     subordinated  the Lease or any of its rights under the Lease to any lien or
     deed of trust prior to the date hereof,  and Tenant  shall not  subordinate
     the Lease or the  rights of the  Tenant  thereunder  to any lien or deed of
     trust other than the Deed of Trust,  without the prior  written  consent of
     NELPP.

          7. This Agreement,  except as otherwise  specifically provided herein,
     shall  inure to the  benefit  of and shall be  binding  upon  HELPP and the
     Trustees,  their  successors  and assigns,  and Tenant,  its successors and
     permitted sublessees and assigns.

          8. This  Agreement  shall be construed in accordance  with the laws of
     the State of Maryland.

          9. Any  reference  to  "foreclosure"  and  'foreclosure  sale' in this
     Agreement  shall include the  acquisition of the  Landlord's  estate in the
     Teased  Premises by voluntary  deed,  assignment,  or other  disposition or
     transfer in lieu of foreclosure.

          10.  This  Agreement  may be  amended  by and  only  by an  instrument
     executed and delivered by each party hereto.


          11. No determination by any court, governmental body or otherwise that
     any  provisions  of this  Agreement or any  amendment  hereof is invalid or
     unenforceable  in any instance shall affect the validity or  enforceability
     of (a) any other such provisions, or (b) such provision in any circumstance
     not controlled by such  determination.  Each such provision  shall be valid
     and  enforceable  to the full  extent  allowed  by, and shall be  construed
     wherever possible as being consistent with, applicable laws.
<PAGE>


IN WITNESS  WHEREOF,  the parties have  executed  this  Agreement as of the date
first set forth above.



WITNESS/ATTEST:                    NEW ENGLAND LIFE PENSION PROPERTIES;
                                   A REAL ESTATE LIMITED PARTNERSHIP

                                   By: Copley Properties Company,
                                   Inc., General Partner

__________________________         BY:____________________________________
                                      Kevin M. Mahony
                                      Vice President            LANDLORD



WITNESS/ATTEST:                    CROP GENETICS INTERNATIONAL
                                   CORPORATION

__________________________         BY:_____________________________________
               
                                                                 TENANT

__________________________         ________________________________________
                                     R. Lawrence Koch, Jr.
                                                                 TRUSTEE

_________________________          ________________________________________
                                     Timothy Dell
                                                                 TRUSTEE

COMMONWEALTH OF MASSACHUSETTS
CITY/COUNTY OF SUFFOLK, TO WIT:

     I HEREBY  CERTIFY  that on this 17 day of  September,  1992,  before  me, a
Notary Public in and for the  aforesaid  State and the  City/County  of Suffolk,
appeared  Kevin  M.  Mahony,  who  acknowledged  himself/herself  to be the Vice
President of Copley  Properties  Company,  Inc.,  general partner to New England
Life Pensio N a lic in and for the aforesaid State and the n Properties;  A Real
Estate Limited  Partnership,  being  authorized so do do, executed the foregoing
instrument  for the  purposes  therein  contained,  by  signing  the name of the
corporation by himself/herself as Vice President. 

     AS WITNESS my hand and notarial seal.

                              __________________________________________
                              Notary Public
                              My Commission Expires:  11/15/91.

<PAGE>

STATE OF MARYLAND
CITY/COUNTY OF HOWARD, TO WIT:


     I HEREBY  CERTIFY  that on this 28 day of  September,  1992,  before  me, a
Notary  Public in and for the  aforesaid  State and the  City/County  of Howard,
appeared Joseph W. Kelly, who acknowledged  himself/herself to be the Pres & CEO
of Crop Genetics International Corporation,  being authorized so to do, executed
the foregoing instrument for the purposes therein contained, by signing the name
of the corporation by himself/herself as Pres. & CEO.
   
     AS WITNESS my hand and notarial seal.

                              __________________________________________
                              Notary Public
                              My Commission Expires:  11/15/91.



STATE OF MARYLAND
CITY/COUNTY OF BALTIMORE, TO WIT:


     I HEREBY CERTIFY that on this 2 day of October,  1992,  before me, a Notary
Public  in and  for  the  aforesaid  State  and the  City/County  of  Baltimore,
personally  appeared R. Lawrence  Koch,  Jr.,  Trustee for the benefit of NELPP,
known to me (or satisfactorily proven) to be the person whose name is subscribed
to the within  instrument  and  acknowledge  that he/she  executed  the same for
purposes therein contained as the duly authorized Trustee for NELPP.
   
  AS WITNESS my hand and notarial seal.

                              __________________________________________
                              Notary Public
                              My Commission Expires:  7/1/94


STATE OF MARYLAND
CITY/COUNTY OF BALTIMORE, TO WIT:

     I HEREBY CERTIFY that on this 2 day of October,  1992,  before me, a Notary
Public  in and  for  the  aforesaid  State  and the  City/County  of  Baltimore,
personally  appeared Timothy Dell, Trustee for the benefit of NELPP, known to me
(or  satisfactorily  proven) to be the person  whose name is  subscribed  to the
within  instrument and  acknowledge  that he/she  executed the same for purposes
therein contained as the duly authorized Trustee for NELPP.
   
  AS WITNESS my hand and notarial seal.

                              __________________________________________
                              Notary Public
                              My Commission Expires:  7/1/94.  
<PAGE>

                               AMENDMENT OF LEASE
 
     THIS AMENDMENT OF LEASE (this "Amendment') is made this 1st day of October,
1992 between M.O.R.  XVIII ASSOCIATES  LIMITED  PARTNERSHIP,  a Maryland limited
partnership  ('Landlord'),   and  CROP  GENETICS  INTERNATIONAL  CORPORATION,  a
Delaware corporation ("Tenant').


                              Explanatory Statement

     A.  Landlord  and Tenant  entered  into a lease dated  October 1, 1992 (the
"Lease')  pursuant to which Landlord  leased to Tenant a parcel of real property
known  as  "Parcel  M-2  and  the  building   constructed   thereon   containing
approximately  seventy-five  thousand five hundred (75,500) square feet, located
in Columbia, Maryland, all as more particularly described in the Lease.


     B. Landlord and Tenant wish to modify and amend  certain  provisions of the
Lease, all as more specifically set forth below.

     NOW,  THEREFORE,  in  consideration  of the Explanatory  Statement which is
incorporated  by reference  herein and deemed a  substantive  part  hereof,  the
covenants of the parties and other good and valuable consideration,  the receipt
and  sufficiency  of which is hereby  acknowledged,  Landlord and Tenant  hereby
agree as follows:


     1.  Section  23 of the Lease is  hereby  amended  by  deleting  the  second
sentence in its entirety and inserting in its place the following:

     Landlord's  liability  under this  Lease  shall be limited to the extent of
     Landlord's interest in the Leased Premises,  so that no partner,  director,
     officer  or  shareholder  of  Landlord,  as it  may  now  or  hereafter  be
     constituted,  or of any  successor  or assign of  Landlord,  shall have any
     personal liability to Tenant and/or any person or entity claiming under, by
     or through Tenant upon any action,  claim,  suit or demand brought under or
     pursuant to the terms and  conditions  of this Lease and/or  arising out of
     the use or occupancy by Tenant of the Leased Premises.

     2. In the  event  that any other  party (a  "Successor")  succeeds  to the
interest of Landlord under this Lease so that M.O.R.  XVIII  Associates  Limited
Partnership is no longer  Landlord,  including any  succession  arising out of a
termination  of the Ground  Lease on Parcel  M-2, a  foreclosure  of the Deed of
Trust on Parcel M-2, or any other  transfer,  sale or  assignment of Parcel M-2,
then Section 23 of the Lease shall  automatically  be deemed further  amended by
revising the phrase  "Landlord's  liability under this Lease shall be limited to
the extent of Landlord's  interest in the Leased  Premises..." to the following:
"Landlord's  liability  under  this  Lease  shall be  limited  to the  extent of
Landlord's interest in Parcel M-2 .... "

     3. Rider No. 2 of the Lease,  among other things,  grants to Tenant certain
expansion  rights with respect to that parcel cf land  contiguous  to Parcel M-2
known as "Parcel  M-3" (the  "Expansion  Parcel'),  and Rider No. 4 of the Lease
grants to Tenant a right of first refusal with respect to the Expansion  Parcel.
Landlord and Tenant hereby agree that if any Successor  becomes  Landlord  under
the Lease so that  M.O.R.  XVIII  Associates  Limited  Partnership  is no longer
Landlord, then all of Landlord's obligations under the Lease with respect to the
Expansion  Parcel  shall be  deemed  severed  from the  Lease,  so that any such
Successor  shall have no  obligations  whatsoever  with respect to the Expansion
Parcel. In such event,  however,  M.O.R.  XVIII Associates  Limited  Partnership
shall  continue to be bound to Tenant with respect to the Expansion  Parcel upon
the terms and conditions  set forth in the Lease,  as amended  hereby,  but such
obligation is personal to M.O.R. XVIII Associates  Limited  partnership and will
not run with the  Expansion  Parcel  or bind any  successor  or assign of M.O.R.
XVIII Associates Limited Partnership.

     4. Rider No. 2 of the Lease is hereby  amended by adding the  following new
paragraph:

     Notwithstanding any language in the Lease to the contrary,  if (a) Landlord
     offers the Expansion  Parcel to Tenant pursuant to Rider No. 4 of the Lease
     (Tenant's  Right of First  Refusal) ; (b) the Right of First Refusal is not
     accepted or is otherwise  rejected by Tenant;  and, (c) Landlord  sells the
     Expansion  Parcel to a third party  pursuant to Rider No. 4, then  Tenant's
     Expansion  Option  with  respect to the  Expansion  Parcel  shall be deemed
     automatically terminated and of no further force and effect.

     5.  Rider No. 6 of the Lease,  Tenant's  Right of  Cancellation,  is hereby
amended by adding the following:


     Notwithstanding  any  language in the Lease to the  contrary,  in the event
     that Tenant  exercises its Expansion  option pursuant to Rider No. 2 of the
     Lease, then Tenant's  Cancellation  Option described herein shall be deemed
     automatically null and void and of no further force and effect.


     6. From and after the date  hereof,  the Lease shall be amended and in full
force  and  effect  in such  respects  as are set  forth  herein,  and all other
provisions, terms, conditions and riders of and to the Lease shall remain as set
forth in the Lease, in full force and effect.

     7. Unless the context requires a contrary  meaning,  all capitalized  terms
not defined herein shall have the meanings ascribed to them in the Lease.
<PAGE>
                             ASSIGNMENT OF SUBLEASE

     THIS ASSIGNMENT OF SUBLEASE  ("Assignment")  is dated as of May 1, 1996, by
CROP GENETICS INTERNATIONAL  CORPORATION,  a Delaware Corporation  ("Borrower"),
and biosys, Inc., a Delaware corporation ("biosys";  together with the Borrower,
collectively, the "Obligors"), to and for the benefit of THE FIRST NATIONAL BANK
OF MARYLAND, a national banking association ("Bank"),  which is the Lender under
the  below-referenced  Financing  Agreement,  as amended, and is the assignee of
Maryland  Industrial   Development  Financing  Authority,  a  body  politic  and
corporate and a public instrumentality of the State of Maryland ("MIDFA").



                                    RECITALS
     Pursuant  to and in  accordance  with  the  Maryland  Economic  Development
Revenue Bond Act, as amended, and the Maryland Industrial  Development Financing
Authority  Act, as amended  ("MIDFA  Act"),  and upon the terms set forth in the
Loan and  Financing  Agreement  dated  December 7, 1994 by and among MIDFA,  the
Borrower and the Bank ("Financing Agreement"), MIDFA issued and sold to the Bank
MIDFA's Taxable Economic  Development Revenue Bond (Crop Genetics  International
Corporation Facility), 1994 Issue, in the principal amount of Three Million Four
Hundred Thousand Dollars ($3,400,000.00)  ("Bond"). MIDFA loaned the proceeds of
the Bond to the  Borrower  in order to  finance  a  portion  of the costs of the
borrower's  acquisition  of a  certain  industrial  facility.  To  evidence  its
obligation  of  repayment,  the Borrower  executed and delivered to the order of
MIDFA the  Promissory  Note dated  December 7, 1994 in the  principal  amount of
Three  Million  Four  Hundred  Thousand  Dollars  ($3,400,000.00)  ("Note").  In
accordance with the Financing Agreement, MIDFA assigned its interest in the Note
and all security for the Note to the Bank as security for the Bond.

     Pursuant to and in accordance with the MIDFA Act, MIDFA provided  financial
assistance  (within the meaning of the MIDFA Act) by insuring,  through its Bond
Insurance  Fund,  repayment of a portion of the principal of and interest in the
Bond in accordance  with the Insurance  Agreement  dated December 7, 1994 by and
among MIDFA,  the Borrower and the Bank. All of the documents  described  above,
together  with all other  documents  executed in  connection  with the financing
transaction  described above, are collectively referred to as the "Original Bond
Documents.'

     The Original Bond Documents have been modified by: (a) the Modification and
Forbearance Agreement dated May 26, 1995 by and among the Borrower,  biosys, the
Bank and MIDFA (the 'First  Modification  Agreement")  pursuant to which,  among
other things,  biosys  guaranteed the payment and  performance of the Borrower's
obligations  under the Original Bond Documents,  as the same may be amended from
time to time, in accordance with a Guaranty Agreement made of even date with the
First Modification  Agreement;  and (b) the Second  Modification and Forbearance
Agreement dated as of October 2, 1995 (the "Second  Modification  Agreement") by
and among the parties to the First  Modification  Agreement,  and various letter
agreements.

     The parties hereto have entered into a Third Modification Agreement of even
date herewith (the "Third Modification  Agreement") which requires,  among other
things,  that the Obligors  give this  Assignment  to and for the benefit of the
Bank. The Obligors are willing to give this  Assignment for the purposes  stated
herein and in the Third Modification Agreement.

     As  used  herein,  the  term  "Bond  Documents"  means  the  Original  Bond
Documents,  as the  same  have  been  modified  as  described  in the  preceding
paragraphs,  together with any and all other documents now existing or hereafter
made to  evidence,  secure or  otherwise  set  forth the terms of the  Obligors'
obligations in connection with the above-described financing.

     NOW,  THEREFORE,  in  consideration  of these  premises  and other good and
valuable   consideration  the  receipt  and  sufficiency  of  which  are  hereby
acknowledged  the  Obligors  agree as  follows,  for the benefit of the Bank and
MIDFA:


     Section 1. Certain Definitions:  Rules of Construction. (a) As used in this
Assignment:

               (i) the term "Obligations" means (A) all amounts now or hereafter
          outstanding under the Note, the Financing Agreement and the other Bond
          Documents, and (B) the Obligors' duties to perform and comply with all
          of the other agreements of the Obligors under the Bond Documents;  and
         
               (ii) except where the context clearly requires  otherwise,  terms
          defined  in the  Recitals  above  shall have the  respective  meanings
          indicated,  and capitalized  terms not otherwise  defined herein shall
          have the respective meanings given in the Third Modification Agreement
          (including  definitions   incorporated  into  the  Third  Modification
          Agreement by reference to another ]Bond Document).
        
          (b) The singular  shall include the plural and the plural may refer to
     only  the  singular;  the use of any  gender  shall  be  applicable  to all
     genders;  the headings and  captions  contained  herein are for purposes of
     convenience  only and are not a part of this  Assignment.  Except where the
     context clearly requires otherwise, when used in this Assignment, the words
     "herein", 'hereof", and "hereunder' and words of similar import shall refer
     to this  Agreement as a whole and not only to any  particular  provision of
     this Agreement;  the words  "Include,"  "Includes' and "including," as used
     herein,  shall be deemed to be followed by the words 'without  limitation';
     and an  "agreement"  (or  another  word of  similar  import) of a person or
     entity shall include any applicable  promise,  representation,  warranty or
     other  undertaking  of such  person or  entity. 

     Section  2.  Assignment  Of  Interest  In  Sublease.  As  security  for the
Obligations, the Obligors hereby grant, transfer and assign to the Bank: (a) all
of the  Obligors'  right,  title and interest in and to the  Sublease  Agreement
dated May 2, 1996 (together with all amendments and supplements  thereto and any
replacements, restatements or substitutions thereof, and all including any other
lease by the Obligors or either of them of their  interest in the  below-defined
Premises or any portion thereof, collectively, the "Sublease") by and among Gene
Logic, Inc., a [Delaware] corporation, as subtenant ("Subtenant"), the Obligors,
as sublandlord,  with respect to the real property located at 10150 Old Columbia
Road, Howard County,  Maryland ('Premises"),  including all of the rights of the
Obligors (or either of them) to receive payments of rent and other amounts which
may  become  owing  to any  Obligor  thereunder;  together  with (b) any and all
deposits of Subtenant to secure payment of the same and performance of the terms
and  conditions of the  Subtenant's  obligations  under the  Sublease;  and also
together with (c) the right to collect the aforesaid  amounts and to utilize any
collection  or  enforcement  rights or remedies  which may be available  to, any
Obligor under law or the Sublease, but without any duty or obligation to perform
on behalf of any Obligor  any  agreement  of the  Obligors  under the  Sublease.
Without limiting the foregoing,  the rights assigned hereunder shall include (1)
any and all rights of the Obligors (or either of them) to receive fees, charges,
reimbursements,   insurance   proceeds,   option  payments,   payments  made  in
consequence  of any  defaults  by  Subtenant  or in  settlement,  compromise  or
satisfaction  of any obligations of Subtenant due the Obligors as a result or in
consequence  of the Sublease,  (2) all claims and rights to the payment of money
at any time arising in connection with the Sublease or breaches of the Sublease,
or any  rejection  of the  Sublease  by  Subtenant  or a trustee of  Subtenant's
bankruptcy  estate under  Section 365 of the United States  Bankruptcy  Code, as
amended,  all rights to recover  damages  arising out of any of such breaches or
rejections,  and (3) all rights to take or receive  charges payable by Subtenant
or trustee of Subtenant  with  respect to the  premises  covered by the Sublease
following  the entry of an order for relief under the United  States  Bankruptcy
Code in respect of such  Subtenant  and all rent and other  charges  outstanding
under the Sublease as of the date of the entry of the order for relief.

     Section 3. Collection of Rent By Obligors. (a) So long as there shall exist
no Event of Default,  the Obligors shall have a license to receive,  collect and
retain  payments of rent and other  amounts  under the Sublease and otherwise to
exercise  the rights and  receive  the  benefits  of the  Sublandlord  under the
Sublease, subject to the provisions of this Assignment.

          (b) Upon,  or at any time  after,  any Event of Default  (unless  such
     Event of Default is waived in  writing by the Bank),  the Bank,  without in
     any way waiving such default, may at its option, terminate such license and
     thereafter  the Bank  shall be  entitled  immediately  and  exclusively  to
     collect all rent and other amounts  payable  under the Sublease;  provided,
     however,  that (i) a portion of each Monthly Payment received in respect of
     Base  Rent  shall be  applied  first to the  Obligors'  obligations  to pay
     Commissions  (hereafter defined) then due, and (ii) amounts received by the
     Bank in respect of estimated  Actual  Operating Costs (under and as defined
     in the Sublease)  shall at the Bank's  option,  (A) be applied  against the
     outstanding  Obligations- in the same manner as amounts received in respect
     of ]3ase Rent under the Sublease,  (B) be held as a reserve for and applied
     to such  Actual  Operating  Costs  as the same  are  incurred,  or (C) some
     combination  of the  foregoing  in such  order  or  proportion  as the Bank
     determines, in its sole discretion. As used in this part (b), "Commissions"
     means the leasing commission payable by the Obligors to Casey & Associates,
     Inc. (together with its successors and assigns, "Broker") in respect of the
     Sublease, in accordance with the provisions of the Agreement between biosys
     and the Broker dated February 28, 1996.  Nothing  contained herein shall be
     construed as any assumption by the Bank of the Obligors'  obligation to pay
     any Commission  from their separate  funds;  rather,  such amounts shall be
     payable  solely from Base Rent actually  received by the Bank. The Obligors
     hereby agree to  indemnify  the Bank and MIDFA from and ag2anst any and all
     liability,  loss,  or damages  which it may or might incur to Broker or any
     person  claiming by,  through or under Broker,  and from any and all claims
     and demands  whatsoever  which may be asserted  against it by reason of any
     alleged  obligations  or  undertakings  on the part of the Bank or MIDFA to
     perform or discharge any of the obligations of the Obligors to Broker other
     than the payment of Commissions then due from amounts actually  received by
     Bank on account of Base Rent.

          (c) The Bank shall not  collect  or  attempt to collect  rent or other
     payments under the Sublease unless an Event of Default shall have occurred.

          (d) The rights and remedies  provided  hereunder shall be nonexclusive
     and shall be in addition to all other remedies and rights  available  under
     the Bond Documents.


     Section 4. Termination Of Assignment.  All rights of the Bank in and to the
Sublease and the Obligors' rights thereunder, including the right to receive and
collect  the  moneys  payable  thereunder,   shall  end  immediately  upon  full
satisfaction by the Obligors of all of the Obligations.

     Section 5. Bank Has All Rights Of Obligors.  The Bank shall have all rights
and  privileges  of the  Obligors,  either as  provided  in the  Sublease  or as
provided  by law with  respect  thereto.  The Bank shall have no  obligation  to
enforce the Bank's  rights and remedies with respect to the Sublease in the name
of or on behalf of the Obligors,  but may do so directly in the Bank's own name.
Anything contained herein to the contrary  notwithstanding,  the Bank shall have
no obligation or duty to enforce  payment or collection of amounts payable under
the Sublease and shall be  accountable  only for such amounts as may actually be
received by the Bank.

     Section 6. No Modification  Of Leases.  The Obligors shall have no right to
cancel,  materially  amend, or materially modify the provisions of the Sublease,
grant any  concessions,  or agree to an assignment by Subtenant  (whether or not
such  assignment is in compliance  with the terms of the Sublease),  without the
Bank's prior written consent (which consent shall not be unreasonably withheld).
For purposes of the preceding  sentence,  amendments to or  modifications of the
term of the Sublease, the amount of rent to be paid thereunder,  or the premises
described therein shall be material  amendments or  modifications.  The Obligors
will make all steps which may be required to preserve and  maintain  Subtenant's
liability under the Sublease and the  enforceability  thereof and shall promptly
advise  the  Bank of any  defense  or  claim  or  alleged  defense  or  claim of
nonliability,  whether in whole or in part, by Subtenant coming to the Obligors'
attention.  The  Obligors  shall not collect any rent from  Subtenant  more than
thirty  (30) days in advance of its due date,  other than the  security  deposit
provided for in the Sublease,  unless such advance payments are held in a manner
disclosed to and approved by the Bank. The Obligors shall not cancel, terminate,
release,  discharge,  compromise, or modify in whole or in part Subtenant's duty
or  obligation  to pay rent without the pnor written  consent of the Bank (which
consent shall not be unreasonably withheld).

     Section 7. Reliance.  The Obligors irrevocably  authorize Subtenant to rely
upon and comply with any notice or demand by the Bank for payment to the Bank of
rent or for performance of any obligation and the Obligors release and discharge
Subtenant from any and all liability to the Obligors for so complying. Subtenant
shall have no right or duty to inquire  as to whether  any Event of Default  has
occurred or is existing.

     Section 8.  Representations  And  Warranties.  The Obligors  represent  and
warrant as follows:

          Section 8. 1.  Binding,  Obligations.  Each Obligor has full power and
     authority  to  execute  this  Assignment,   and  upon  its  execution  this
     Assignment shall be the binding obligation of the Obligors.
        
          Section  8.2.  Sublease.   The  Sublease  is  the  valid  and  binding
     obligation  of the Obligors  and the  Subtenant,  and has been  effectively
     consented  to by the  Landlord  under the Prime  Lease (as  defined  in the
     Sublease).  The Sublease is fully enforceable in accordance with its terms,
     and neither the  Subtenant nor the Obligors are in default under any of the
     terms thereof.

     Section 9.  Notification.  The Obligors  shall notify the Bank  promptly In
writing of any default by the Obligors in the  performance of or compliance with
any of their agreements under the Sublease or any notice of default or notice of
termination  received by any Obligor.  The Obligors  shall  deliver to the Bank,
promptly  after  any  Obligor's  receipt  thereof,  a copy of each  such  notice
received by the Obligor.

     Section 10. Notice Of Arbitration Or Litigation.  The Obligors shall notify
the Bank and  MIDFA  promptly  in  writing  in the  event of  initiation  of any
arbitration or litigation proceeding under or pursuant to the Sublease and, upon
the request of the Bank,  shall exercise all rights of arbitration or litigation
provided by the Sublease.  The Bank shall have the right to  participate  in all
such  arbitration or litigation  proceedings in association with the Obligors or
on its own behalf as an  interested  party;  provided,  that  unless an Event of
Default  shall have  occurred,  all expenses of the Bank  incurred in connection
therewith shall be paid by the Bank.

     Section 11.  Assignment Of Interest.  The Obligors  shall not,  without the
prior  written  consent  of the Bank and  MIDFA,  further  assign,  transfer  or
encumber  their interest in the Sublease or permit the  assignment,  transfer or
encumbrance of its interest in the Sublease.

     Section 12. Further  Assurances.  The Borrower shall execute and deliver on
request of the Bank or MIDFA from time to time such confirmatory  assignments or
other  instruments as the Bank or MIDFA may reasonably  deem useful or necessary
to carry out the purposes of this Agreement.

     Section 13. Performance Of Obligations.  The Bank shall not be obligated to
perform  or  discharge,  nor  does the  Bank  hereby  undertake  to  perform  or
discharge,  any  obligation,  duty or liability  under the Sublease or the Prime
Lease,  under or by reason of this  Assignment,  and the  Obligors  shall and do
hereby agree to indemnify the Bank and MIDFA for, and to hold the Bank and MIDFA
harmless  of, and from,  any and all  liability,  loss or damage which it may or
might  incur  under  the  Sublease  or the  Prime or under or by  reason of this
Assignment,  and from any and all claims  and  demands  whatsoever  which may be
asserted against it by reason of any alleged  obligations or undertakings on the
part of the Bank or MIDFA to perform or discharge any of the terms, covenants or
agreements  contained  in the  Sublease  or the Prime . Should the Bank or MIDFA
incur any such  liability,  loss or damage under the Sublease or the Prime Lease
or under or by reason of this  Assignment  or in defense  of any such  claims or
demands, the amount thereof, including costs, expenses and reasonable attorneys'
fees, shall be secured hereby and the Obligors shall reimburse the Bank or MIDFA
therefore immediately upon demand, and upon the failure of Obligors so to do the
Bank may declare a11 of the Obligations due and payable.

     Section 14. No Waiver.  Nothing herein contained and no act done or omitted
by the Bank pursuant to the powers and rights  granted it herein shall be deemed
to be a waiver by the Bank of its rights and remedies under the Bond  Documents,
but this Assignment is made and accepted without  prejudice to any of the rights
and  remedies  possessed by the Bank under the terms  thereof.  The right of the
Bank to collect the indebtedness  and to realize on any other security  securing
the  Obligations  may be exercised  by the Bank either prior to,  simultaneously
with, or subsequent to any action taken by it hereunder.

     Section 15.  Assignment of Bond  Documents.  In the event any or all of the
Bond Documents are assigned and transferred by the Bank, the Borrower  covenants
and agrees that all of the provisions  herein  contained shall be applied to and
inure to the benefit of the transferee in the same manner and to the same extent
as if it was the original assignee of the Sublease herein named.


     Section 16. Binding Nature.  This Assignment  shall inure to the benefit of
the Bank and the Bank's  successors  and assigns  and shall be binding  upon the
Borrower and the Borrower's  successors and assigns.  This Assignment may not be
amended  or  modified  except  by a  writing  executed  by both the Bank and the
Borrower.

     Section 17. Final Agreement.  This Assignment contains the final and entire
agreement of the parties  relating to the assignment of the Borrower's  interest
in the Sublease.

     Section 18.  Choice Of Law.  The laws of the State of Maryland  (excluding,
however,  conflict of law  principles)  shall govern and be applied to determine
all issues  relating to this  Assignment  and the rights and  obligations of the
parties  hereto,  including  the  validity,  construction,  interpretation,  and
enforceability   of  this   Assignment  and  its  various   provisions  and  the
consequences  and legal effect of all  transactions and events which resulted in
the execution of this  Assignment or which occurred or were to occur as a direct
or indirect result of this Assignment having been executed.

                   [Signatures and Acknowledgments Follow.]

<PAGE>



     IN WITNESS WHEREOF,  the Borrower has duly executed this Assignmerit  under
seal as of the date first above written.


WITNESS/ATTEST:                    CROP GENETICS INTERNATIONAL
                                   CORPORATION
                                   A Delaware Corporation

________________________           BY:_________________________________(SEAL)
                                      Name:  Edwin C. Quattlebaum
                                      Title: President/CEO



                                   BIOSYS, INC.
                                   A Delaware Corporation

_______________________            BY:_________________________________(SEAL)
                                      Name:  Edwin C. Quattlebaum
                                      Title: President/CEO

<PAGE>


                                ACKNOWLEDGEMENTS


STATE OF MARYLAND, CITY/COUNTY OF ANNE ARUNDEL, TO WIT:

     I  HEREBY  CERTIFY  that on  this  7th day of May,  1996,  before  me,  the
undersigned Notary Public of the State of Maryland, personally appeared Edwin C.
Quattlebaum,  and  acknowledged  that he is the President & CEO of CROP GENETICS
INTERNATIONAL  CORPORATION,  a  Delaware  Corporation,  and  that  he,  as  such
President and CEO, being authorized to do so, executed the foregoing  instrument
for  the  purposes  therein  contained  by  signing  the  name  of the  Delaware
corporation by himself as Edwin C. Quattlebaum.


     IN WITNESS MY Hand and Notarial Seal.

                                             __________________________(SEAL)
                                             NOTARY PUBLIC

My Commission Expires:
 
    6/24/98


STATE OF MARYLAND, CITY/COUNTY OF ANNE ARUNDEL, TO WIT:

     I  HEREBY  CERTIFY  that on  this  7th day of May,  1996,  before  me,  the
undersigned Notary Public of the State of Maryland, personally appeared Edwin C.
Quattlebaum,  and acknowledged that he is the President & CEO of BIOSYS, INC., a
Delaware  Corporation,  and that he, as such President and CEO, being authorized
to do so, executed the foregoing  instrument for the purposes therein  contained
by  signing  the  name of the  Delaware  corporation  by  himself  as  Edwin  C.
Quattlebaum.

     IN WITNESS MY Hand and Notarial Seal.

                                             __________________________(SEAL)
                                             NOTARY PUBLIC

My Commission Expires:
 
    6/24/98


<PAGE>
                         Exhibit of Key Plan Floor Plan
                                 Graphic Image
                                  See Apendix
<PAGE>
                            Expansion of Floor Plan
                                 Graphic Image
                                  See Appendix
<PAGE>



                                    EXHIBIT F
                     Gene Logic - biosys Sub-Lease Agreement

                     Permitted Uses of Sub-Leased Premises


     The  Sub-Tenant  shall  not use or  permit  the use of any  portion  of the
Sub-Leased Premises for any purpose other than the following:


     The office space shall be used for general  office and  corporate  purposes
and the laboratory  space shall be used to conduct  biomedical  research and for
the provision of genomic  information and services to clients in the health care
industry.  Specifically,, the Sub-Tenant may use the Sub-Leased Premises for the
following:

     1.   the culture of mammalian  cells and other  prokaryotic  and eukaryotic
          organisms; 1

     2.   extraction and manipulation of nucleic acids from such cells;

     3.   general  molecular  biology  activities,  which  includes  the  use of
          low-level   radioisotopes  (under  proper  local,  stat6  and  federal
          licensing),  and small amounts of organic  chemical waste that will be
          disposed of properly;

     4.   capture of information in computer databases; and,

     5.   to-and-fro transmission of data over Ll or ISDN lines.


     Sub-Tenant  may use the laboratory  space for other  laboratory or research
purposes, provided, that Sub-Tenant obtain Sub-Landlord's written consent before
undertaking  any  such  activity.   The  Sub-Landlord's  consent  shall  not  be
unreasonably withheld.
<PAGE>


                                   Exhibit G.
        biosys personal property inventory contained in subleased space


QTY                           ITEMS

2                   Cherry wood dry erase cabinets
1                   4'x5' wood frame dry erase board
1                   4'x7' metal frame dry erase board
4                   8'x10' modular cubicles
4                   Overhead bins for modular cubicles
42'                 Desk tops for modular cubicles
1                   Labconco "Protector" 5' Laboratory Hood
1                   Labconco "Protector" 4' Laboratory Hood
1                   Corning "Mega Pure" Distilled water system
                    All casework and fixtures
                    All fire extinguishers
<PAGE>
Exhibit H
Graphic Image
See Appendix
<PAGE>



                                   EXHIBIT I
                     Gene Logic - biosys Sub-Lease Agreement

                  Improvements To Be Made by Gene Logic, Inc.


     The following  Improvements  to the  Sub-Leased  Space will be made by Gene
Inc., at its sole cost:


     Room B - Analytical  Lab: Remove eleven feet of casework and eleven feet of
wall cabinetry. Remove eleven feet of electrical strip along same wall. Add air,
vacuum,  and gas  connections  from main  building  systems for two locations on
north wall.  Repair floor where  casework was removed if necessary.  Provide and
install eleven feet of vinyl base molding where  casework was removed.  Add four
feet of kneespace along  cabinetry on south wall.  Provide and install four foot
standard laboratory sink with HW/CW/Dl faucets on south wall in corner.

     Room C - New Lab Area:  Install one eleven foot  casework  section that was
removed from Room B above as half of one island section.  Install second half of
this eleven foot sect' ion and sink including  HW/CW/DI  faucet.  Install second
eleven foot island  casework  section.  Install air,  gas,  vacuum along islands
drawing from main building systems. Vent at least one cabinet area outside using
existing vent tube along north wall.

     New Cafeteria: Provide and install new three foot door with glass window in
door.  Provide  and  install  new three foot by five foot  window in wall facing
atrium. Install new kitchen cabinet with sink including HW/CW.

     Open Office Area:  Demolish  three walls and one door  totaling 28.5 linear
feet. Repair ceiling grid and tile if necessary.
<PAGE>
Graphical Image Appendix

Page 25   Sublease Agreement Exhibit A 
          Description - Site Plan for 10150 Old Columbia Road, Columbia, MD

Page 48   Lease Agreement Exhibit A
          Description - Site Plan for 10150 Old Columbia Road, Columbia, MD

Pages 51 - 68  Lease Agreement Exhibit D
               Description - United States Environmental Protection Agency
               1991 Hazardous Waste Reports Forms 1C and GM-Identification
               and Certification - 16 Pages

Page 80   Sublease Agreement Exhibit D
          Description - Architectural Drawing of 10150 Old Columbia Rd.,
          Columbia, MD - Outline of Leased Premises

Page 81   Sublease Agreement Exhibit E
          Description - Architectural Drawing of 10150 Old Columbia Rd.,
          Columbia, MD - Outline of future leasable area for expansion

Page 84   Sublease Agreement Exhibit H
          Description - Architectural Drawing of 10150 Old Columbia Rd.,
          Columbia, MD - Improvements and walls to be constructed as a result
          of sublease agreement






TEXT>
THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.68 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.


                          THIRD MODIFICATION AGREEMENT

     THIS THIRD MODIFICATION  AGREEMENT  ("AGREEMENT") is made as of the 1st day
of May, 1996, by and among CROP GENETICS INTERNATIONAL CORPORATION ("BORROWER"),
biosys, Inc. ("BIOSYS"), THE MARYLAND INDUSTRIAL DEVELOPMENT FINANCING AUTHORITY
("MIDFA"),  and THE FIRST NATIONAL BANK OF MARYLAND  ("BANK").  The BORROWER and
BIOSYS are hereafter collectively referred to as the "OBLIGORS" .
                                 R E C I T A L S

     Reference is made to the Modification  Agreement dated May 26, 1995 ("FIRST
MODIFICATION  AGREEMENT")  and the  Second  Modification  Agreement  dated as of
October 2, 1995 ("SECOND  MODIFICATION  AGREEMENT"),  each made by and among the
OBLIGORS,  MIDFA and the BANK, the various letter  agreements  relating  thereto
(collectively,  the "LETTER AGREEMENTS"). and all of the other "BOND DOCUMENTS,"
as that term is defined in the SECOND MODIFICATION AGREEMENT.
      
     All of the documents  described  above,  together with all other  documents
heretofore  executed in  connection  with the  financing  evidenced  by the BOND
DOCUMENTS,  are  hereafter  collectively  referred  to  as  the  "EXISTING  BOND
DOCUMENTS."  The EXISTING BOND DOCUMENTS,  this  AGREEMENT,  all documents to be
executed  pursuant to this AGREEMENT,  and II other documents  relating  thereto
and/or executed in connection therewith,  are hereafter collectively referred to
as the "BOND DOCUMENTS." The OBLIGORS" total  indebtedness to the BANK under the
BOND DOCUMENTS including,  without limitation, all principal, accrued and unpaid
interest,  late charges,  costs,  expenses and attorneys'  fees now or hereafter
owed  thereunder,  is hereafter  referred to as the  "INDEBTEDNESS".  All assets
which now or hereafter serve as security for the,:  INDEBTEDNESS that is owed to
the BANK under the BOND DOCUMENTS are hereafter  collectively referred to as the
"COLLATERAL."

     Pursuant to the EXISTING BOND DOCUMENTS,  upon the entry by the OBLIGORS of
any sublease of the premises at 10150 Old Columbia Road, Columbia, Maryland, the
OBLIGORS  shall  specifically  assign to MIDFA and the BANK, as security for the
INDEBTEDNESS,  all of the  OBLIGORS'  right,  title and  interest in and to such
sublease,  including all rent payable thereunder.  The OBLIGORS have proposed to
enter into such a sublease (the "SUBLEASE") with Gene Logic, Inc. ("SUBTENANT"),
substantially in the form attached hereto as Exhibit 1, and have agreed to enter
into an Assignment  of Sublease  substantially  in the form  attached  hereto as
Exhibit 2 (the "SUBLEASE, ASSIGNMENT").

     The SECOND MODIFICATION,  as amended, requires that the OBLIGORS enter into
a supplement to such SECOND  MODIFICATION  establishing  financial  covenants of
BIOSYS,  for the benefit of the BANK, in form and substance  satisfactory to the
BANK.  BIOSYS has requested that the, BANK agree to modify the requirement  that
BIOSYS establish financial covenants. In connection with such request, BIOSYS is
willing to covenant that,  upon the entry into any agreement  between BIOSYS and
Imperial  Bank or any other  person  whereby  BIOSYS  agrees to comply  with any
financial  test or covenant,  BIOSYS shall become bound,  for the benefit of the
BANK, to comply with  substantially  the same  financial  tests or covenants and
shall execute such documentation as the BANK may reasonably require to establish
such obligation.

     Pursuant to an agreement dated September 15, 1995 (the "ZENECA  AGREEMENT")
between BIOSYS and Zeneca, Ltd. ("ZENECA"),  the OBLIGORS have proposed to grant
to ZENECA,  under certain  circumstances,  a conditional  right of first refusal
with respect to certain equipment owned by the BORROWER and/or BIOSYS,  which is
described  on  Exhibit  3  hereto,  and have  requested  that the BANK and MIDFA
consent to such right of first refuse and, upon the exercise thereof, permit the
conveyance of such  equipment  provided that ZENECA pays the BANK the applicable
purchase  price.  To induce  the BANK and  MIDFA to give  their  consent  to the
foregoing,  the OBLIGORS  have offered to grant to MIDFA and the BANK a security
interest in such equipment in accordance with a Supplemental  Security Agreement
in the form attached hereto as Exhibit 4 ("SUPPLEMENTAL SECURITY AGREEMENT").

     The BANK and MIDFA have now had an  opportunity  to review  the  Borrowers'
various requests, and in connection therewith, are willing to agree as follows.

                              W I T N E S S E T H:

     NOW, THEREFORE,  in consideration of the foregoing premises,  and for other
good and  valuable  consideration,  the receipt and adequacy of which are hereby
acknowledged,  the  parties  hereto,  intending  to be legally  bound,  agree as
follows:
          1.  Recitals.  The Recitals set forth above,  are true and accurate in
     every respect and are hereby incorporated into this AGREEMENT by reference.
    
          2.  Definitions:  Miscellaneous.  The term "EVENT OF DEFAULT"  has the
     meaning given in Section 10 hereof.  Terms defined in the Recitals above or
     elsewhere in this AGREEMENT shall have the respective  meanings  indicated.
     Terms set forth  herein in all capital  letters but not  otherwise  defined
     herein  shall  have the  respective  meanings  given to those  terms in the
     SECOND MODIFICATION AGREEMENT (including  definitions  incorporated therein
     by reference to another EXISTING BOND DOCUMENTS).
     
          3.   Acknowledgements  of  outstanding  Balance:   Transaction  Costs:
     modification  Fee. 

          (a) The  OBLIGORS  hereby  acknowledge  and agree that  through May 2,
     1996,  the  outstanding  principal  and interest  balance owing to the BANK
     under the BOND DOCUMENTS was as follows:
     Principal: ..................................    $   2,550,006.46

     Interest through 5/2196: ....................            1,239.58

     TOTAL Principal and Interest
     Balance Owing to the
     BANK under the BOND DOCUMENTS
     through 5/2/96: .............................    $   2,551,246.04

          In addition,  the OBLIGORS are obligated to pay to the BANK all actual
     costs,  expenses  and  attorneys'  fees which the BANK has  incurred or may
     incur in the  future  under  or in  connection  with  the  BOND  DOCUMENTS,
     including, but not limited to all costs, expenses and attorneys' fees which
     the BANK has incurred and may incur in the future in preparing, negotiating
     and   consummating   this   AGREEMENT,   and  in  preparing,   negotiating,
     consummating  and/or  recording any and all other  documents  called for in
     and/or  contemplated  by this  AGREEMENT.  All  such  costs,  expenses  and
     attorneys'  fees incurred by the BANK under or in connection  with the BOND
     DOCUMENTS  on or before  May 2, 1996 shall be paid by the  OBLIGORS  to the
     BANK  simultaneously  with the  execution of this  AGREEMENT by the parties
     hereto.  All such costs,  expenses and attorneys' fees incurred by the BANK
     under or in connection  with the BOND DOCUMENTS  after May 2, 1996 shall be
     paid  by the  OBLIGORS  to the  BANK  in  accordance  with  the  terms  and
     conditions of Section 21 of the FIRST MODIFICATION AGREEMENT.
            
          (b) Upon the  execution and delivery of this  Agreement,  the Borrower
     shall  pay a  non-refundable  modification  fee of  Five  Thousand  Dollars
     ($5,000.00).  No  portion of such  modification  fee :shall be applied as a
     payment of principal, interest or expenses.

          4. Confirmation of Obligation.  The OBLIGORS  acknowledge,  ratify and
     confirm their respective obligations under the EXISTING BOND DOCUMENTS, and
     further  acknowledge,  ratify and confirm  that the  OBLIGORS are and shall
     remain  absolutely  and  unconditionally  obligated  to pay  the  BANK  all
     INDEBTEDNESS  that  is owed to the  BANK  under  the  BOND  DOCUMENTS.  The
     OBLIGORS  acknowledge  and agree  that  there  exists no offset  against or
     defense to the duties of the  OBLIGORS  to timely pay the  INDEBTEDNESS  in
     accordance  with the terms of the EXISTING BOND  DOCUMENTS,  as modified by
     this AGREEMENT,  and further agree to perform and comply with the OBLIGORS'
     other  agreements  under the EXISTING BOND  DOCUMENTS,  as modified by this
     AGREEMENT the event that any such offset or defense  exists as of the later
     of the date hereof or the date on which all conditions  precedent set forth
     in Section 8 hereof are  satisfied,  the OBLIGORS  hereby  irrevocably  and
     fully waive and release the same.
   
          5. Sublease: Assignment of Sublease. Simultaneously with the execution
     of this  AGREEMENT by the parties  hereto,  the OBLIGORS  shall execute and
     deliver  the  SUBLEASE  ASSIGNMENT  to and for the  benefit of the BANK and
     MIDFA, in the form attached hereto as Exhibit 2.
    
          6. Financial Covenants of Biosys. Until the full and final payment and
     satisfaction of the INDEBTEDNESS,  in the event that BIOSYS enters into any
     agreement  (or  modification  of any  agreement)  with Imperial Bank or any
     other person  whereby  BIOSYS  agrees to comply with one or more  financial
     covenants or tests with respect to the current loan  facility from Imperial
     Bank or any  replacement  thereof,  then BIOSYS  shall,  in each  instance,
     promptly upon the  effectiveness  of such agreement,  fully disclose to the
     BANK and MIDFA the terms of the applicable  financial covenants or test and
     BIOSYS shall  automatically  become bound to comply with  substantially the
     same financial  covenants or tests for the benefit of the BANK. If required
     by the BANK at any time or from time to time,  BIOSYS  shall  execute  such
     reasonable  documentation as the BANK may. deem necessary or appropriate to
     confirm BIOSYS' agreement to comply with such financial covenants or tests.
     Further,  BIOSYS  shall  provide  the BANK with  certificates  of the chief
     financial  officer of BIOSYS,  not less frequently than quarterly,  setting
     forth  whether  BIOSYS  is in  compliance  with  all  applicable  financial
     covenants or tests and  calculating  the same.  Without  limiting any other
     provision  of the  BOND  DOCUMENTS  whereby  BIOSYS  is  bound  to  provide
     financial  statements or information to the BANK, BIOSYS shall also provide
     the BANK with all other  financial  statements and  information as the BANK
     may  reasonably  require to monitor BIOSYS  compliance  with the applicable
     financial covenants.

          7. Supplemental  Security  Agreement:  Consent to Conditional Right of
     First Refusal.  (a) Simultaneously  with the execution of this AGREEMENT by
     the parties hereto, the OBLIGORS shall execute and deliver the SUPPLEMENTAL
     SECURITY  AGREEMENT  to and for the  benefit of the BANK and MIDFA,  in the
     form  attached  hereto as Exhibit 4, and shall also execute and cause to be
     recorded financing  statements  sufficient to perfect the lien and security
     interest  of the  BANK  and  MIDFA  in the  collateral  described  in  such
     SUPPLEMENTAL  SECURITY  AGREEMENT (such collateral is referred to herein as
     the "ADDITIONAL COLLATERAL").
           
              (b) In  accordance  with the ZENECA  AGREEMENT,  the OBLIGORS may
          grant to ZENECA a  conditional  right of first  refusal (the "RIGHT OF
          FIRST REFUSAL") in the ADDITIONAL COLLATERAL or so much thereof as may
          remain,  exercisable by ZENECA (i) in the event BIOSYS  institutes any
          voluntary Insolvency  Proceedings( (hereafter defined), or (ii) in the
          event involuntary Insolvency Proceedings are instituted against BIOSYS
          and such involuntary  Insolvency  Proceedings are not  unconditionally
          dismissed  within 60 days thereafter;  provided,  that the exercise of
          such right of first  refusal  shall be  subject to the  consent of the
          BANK, which shall be given only upon the satisfaction of the following
          conditions: 

                    (i) the  consideration to be paid by ZENECA for the purchase
               of the ADDITIONAL  COLLATERAL  shall be in an amount equal to the
               fair market value of the ADDITIONAL COLLATERAL, as of the time of
               the exercise of the right of first  refusal,  as determined by an
               appraisal  thereof performed at the expense of the OBLIGORS by an
               independent  appraiser  satisfactory  to the  BANK  (in its  sole
               discretion),  and shall be paid in immediately available funds by
               wire transfer to the BANK, for the account of the OBLIGORS, to be
               applied as a reduction against the INDEBTEDNESS (without limiting
               the foregoing,  no portion of such  consideration  may be paid by
               application  of any set-off or other claim which  ZENECA may have
               against BIOSYS);

                    (ii) the  financing  statements  describing  the  ADDITIONAL
               COLLATERAL  shall have been filed among the public  records where
               such filing is  necessary  or  appropriate  to perfect the BANK'S
               security  interest  in the  ADDITIONAL  COLLATERAL,  and the BANK
               shall have  received  record  search  reports or other  evidence,
               satisfactory to the BANK,  that the BANK'S  security  interest in
               the ADDITIONAL COLLATERAL constitutes a perfected, first priority
               security interest;
                         
                    (iii)  in  the  event  there  exists  any  interest  in  the
               ADDITIONAL COLLATERAL at the time of the exercise of the RIGHT OF
               FIRST REFUSAL (whether  consensual or  non-consensual)  held by a
               person or entity other than the BANK or MIDFA,  the  holder(s) of
               such subordinate interest(s) shall have waived any and all rights
               such  holder(s)  may have in the  ADDITIONAL  COLLATERAL  and the
               proceeds  thereof,  or such rights  shall have been  extinguished
               pursuant to an order of the applicable  Bankruptcy Court or other
               court having jurisdiction;
                       
                    (iv)  the  OBLIGORS  shall  have  obtained  an  order of the
               Bankruptcy  Court  In which  the  applicable  Bankruptcy  case is
               pending, authorizing the transfer of the ADDITIONAL COLLATERAL to
               ZENECA pursuant to the RIGHT OF FIRST REFUSAL and the other terms
               referenced  herein,  and  shall  have  otherwise   satisfied  all
               requirements of applicable law with respect to such transfer; and
                         
                    (v)  the  BANK'S  rights  and  claims  against  BIOSYS,  the
               BORROWER and the COLLATERAL shall remain unimpaired to the extent
               of any INDEBTEDNESS  remaining after  application of the proceeds
               payable on account of the sale of the ADDITIONAL COLLATERAL,  and
               the BANK shall receive such reasonable further assurances thereof
               as it may require.
          
          As used  herein,  "Insolvency  Proceedings"  means with respect to any
     Person:  (a) any case or  proceeding  commenced  by or against such Person,
     under any provision of the United States  Bankruptcy  Code, as amended,  or
     under any other  bankruptcy or insolvency  Law; (b) any assignments for the
     benefit of  creditors,  formal or  informal  moratoriums,  compositions  or
     extensions  with some or all creditors with respect to any  indebtedness of
     such  Person;  (c) the  appointment  of a  receiver,  assignee,  custodian,
     trustee or similar  official under any insolvency or creditors'  rights Law
     for any property of such Person. 8. Conditions Precedent. The agreements of
     the BANK  hereunder  shall be effective only upon the  satisfaction  of the
     following conditions:

          (a) this  AGREEMENT  shall  have been duly  authorized,  executed  and
     delivered by all parties hereto;
               
          (b) the SUBLEASE and the SUBLEASE  ASSIGNMENT shall have been executed
     by all parties thereto;

          (c) the SUPPLEMENTAL  SECURITY AGREEMENT and the financing  statements
     made pursuant  thereto shall have been  "executed and delivered to the BANK
     and MIDFA;

          (d) all of the  representations  and  warranties of the OBLIGORS under
     Section 9 hereof shall be true and correct in all material respects; and

          (e) the OBLIGORS shall have paid the modification fee and the expenses
     incurred by the BANK through May 2, 1996, as required by Section 3 hereof.

    
          9. Representations and Warranties of the Obligors. The OBLIGORS hereby
     severally  represent and warrant to the BANK as follows as of the effective
     date hereof and as of the date of execution  and delivery  hereof (if other
     than the effective date hereof):
         
               (a)  all  matters  represented  and  warranted  by  the  OBLIGORS
          pursuant to Section 9 of the SECOND MODIFICATION AGREEMENT continue to
          be true and correct as of the date of this AGREEMENT;

               (b) each OBLIGOR has the power to enter into this  AGREEMENT  and
          the  transactions  contemplated  hereby,  and such entry has been duly
          authorized by each such OBLIGOR;

               (c) each OBLIGOR has duly executed and delivered this AGREEMENT;

               (d) this AGREEMENT and the other BOND DOCUMENTS are the valid and
          binding obligations of the OBLIGORS,  am fully enforceable against the
          OBLIGORS in accordance with their  respective  terms,  and as to which
          none of the OBLIGORS has any set- off, defense or counterclaim;

               (e) the ADDITIONAL  COLLATERAL is more particularly  described in
          the  SUPPLEMENTAL   SECURITY   AGREEMENT,   and  all  such  ADDITIONAL
          COLLATERAL  is  owned by the  BORROWER  free  and  clear of any  lien,
          assignment,  security  interest  or other  interest  of any  person or
          entity  except the first  priority duly  perfected  liens and security
          interests  of the BANK,  pursuant to the terms and  conditions  of the
          SUPPLEMENTAL SECURITY AGREEMENT and the other BOND DOCUMENTS; and

               (f) no EVENT OF DEFAULT exists under any of the BOND DOCUMENTS
        
          10. Events of Default.  The occurrence of any of the following  events
     or  circumstances  shall  constitute an event of default (each an "EVENT OF
     DEFAULT") hereunder and under the other BOND DOCUMENTS:

               (a) any failure by the  OBLIGORS to pay any amount due on account
          of fees and expenses  incurred  subsequent to May 2, 1996, as required
          by Section 3 hereof,  if such failure  continues  for more than 5 days
          after written notice thereof from the BANK to the OBLIGORS;
                
               (b) any failure by the OBLIGORS to make, in a timely manner,  any
          of the other payments required under the BOND DOCUMENTS, time being of
          the essence;
              
               (c) any  representation  or warranty  made by the OBLIGORS  under
          Section 9 or  Section 12 hereof  shall fail to be true and  correct in
          any material respect as of the date made or deemed made;

               (d) any  failure  by BIOSYS to notify  the BANK of any  agreement
          whereby BIOSYS  becomes bound to comply with any financial  covenants,
          as required  by Section 6 hereof;  or any failure by BIOSYS to execute
          and  deliver to the BANK any  document  required  to be  executed  and
          delivered by BIOSYS pursuant to Section 6 unless such failure is cured
          within 10 days after written notice from the BANK to the OBLIGORS;

               (e) any failure of either OBLIGOR to perform or otherwise  comply
          with  any of  their  other  covenants  or  agreements  under  the BOND
          DOCUMENTS, which failure continues beyond any applicable grace or cure
          period;

               (f) any event of default  under the credit  agreement  or related
          documents between BIOSYS and Imperial Bank, or under any documentation
          for any subsequent credit facility provided to BIOSYS by any lender or
          lenders,  unless  the same is cured or waived in  accordance  with the
          applicable documentation; or

               (g) any other event or circumstance which constitutes an EVENT OF
          DEFAULT or an event of default under any BOND DOCUMENT  (provided that
          any  applicable   cure  period  has  expired  without  such  event  or
          circumstance being cured).

          11.  Rights  and  Remedies  Upon  Default.  If,  after the date of the
     execution  of this  AGREEMENT  by the parties  hereto,  an EVENT OF DEFAULT
     occurs  under this  AGREEMENT or under any other BOND  DOCUMENT,  the BANK,
     after the  expiration  of any  applicable  cure period,  shall be entitled,
     immediately and without further notice or demand, to (a) accelerate payment
     of all INDEBTEDNESS that is owed to the BANK under the BOND DOCUMENTS;  (b)
     confess judgment against the OBLIGORS  pursuant to the terms and conditions
     of paragraph 23 of the FIRST  MODIFICATION  AGREEMENT for all  INDEBTEDNESS
     that is owed at that  time to the BANK  under the BOND  DOCUMENTS;  and (c)
     assert and enforce all other rights and remedies which are available to the
     BANK under this AGREEMENT, the other BOND DOCUMENTS and applicable law with
     respect to the OBLIGORS and their respective  assets.  12. Corporate Status
     of-Borrower;  Franchise Tax Liability.  The Secretary of State of the State
     of  Delaware  declined  to issue a  certificate  of good  standing  for the
     BORROWER  when  requested  to do  so in  connection  with  this  Agreement,
     indicating  that  $148,019.45  in  1995  franchise  taxes  are  owed by the
     BORROWER. The BORROWER and BIOSYS have disputed this amount and assert that
     the  BORROWER'S  good  standing in the state of Delaware can be restored by
     the filing of amended franchise tax returns for the BORROWER and BIOSYS and
     the  payment  of the  estimated  amount  set  forth in item (c)  below.  In
     addition  to the  representations  and  warranties  set forth in  Section 9
     above,  the OBLIGORS hereby represent and warrant that, as of the effective
     date of this Agreement and as of the date of execution and delivery of this
     Agreement:

          (a) the  BORROWER is  incorporated  in the State of  Delaware  and its
     charter has not been revoked,  although a good standing  certificate is not
     presently  available from the Delaware Secretary of State, and the BORROWER
     remains  authorized  to  exercise  Its powers  recited in its  articles  of
     incorporation and transact business in the State of Delaware;

          (b) the BORROWER is duly  authorized to exercise its powers recited in
     its  articles  of  incorporation  and  transact  business  in the  State of
     Maryland,  as indicated in the Certificate  dated May 2, 1996 issued by the
     Maryland State Department of Assessments and Taxation;
      
          (c) the  liability of the  BORROWER for the payment of 1995  franchise
     taxes to the State of  Delaware  is  estimated  by  BORROWER  not to exceed
     $4,000.00,  reflecting an estimated  total 1995 franchise Tax liability for
     BORROWER  of  approximately  $10,000.00,  as against a  creditor  $3,760.08
     currently  due to  BORROWER  from  the  Delaware  Secretary  of  State  for
     over-payment  of its 1994 franchise tax fees,  and an additional  $2,436.00
     credit due to BIOSYS based on its amended 1995  franchise  tax return to be
     filed  forthwith,  which  credits  the  Delaware  Secretary  of  State  has
     indicated it will apply toward BORROWER's 1995 obligations; and
              
          (d) the only requirements to be satisfied by the BORROWER in restoring
     its  good  standing  in the  State  of  Delaware  are the  payment  of 1995
     franchise taxes in an amount estimated not to exceed that indicated in item
     (c) above and the filing of  amended  franchise  tax  returns  and  related
     documentation,  as required,  in the forms thereof prescribed by applicable
     law (provided, that no such documentation shall result in any impairment of
     the BORROWER's status described in items (a) and (b) above).
   
         Further,  the OBLIGORS covenant that, within 30 days after the date of
     this Agreement, they shall provide the Bank and MIDFA with written evidence
     that the  requirements  described  in item (d) above  have been  satisfied,
     which  evidence  shall  consist of copies of the  franchise  tax return and
     other  applicable  documentation,  evidence  of payment  of the  applicable
     franchise tax, and an original  certificate of good standing  issued by the
     Delaware Secretary of State.

          13. Consent and Approval of MIDFA;  Acknowledgment of Liability: Other
     Agreements. MIDFA consents to and approves the terms and conditions of this
     AGREEMENT and the BANK's and OBLIGORS' execution thereof,  and acknowledges
     and agrees that the MIDFA  INSURANCE  AGREEMENT,  as modified by' the FIRST
     MODIFICATION  AGREEMENT,  the  SECOND  MODIFICATION  AGREEMENT,  the LETTER
     AGREEMENTS  and  this  AGREEMENT   (collectively,   the  "MIDFA   INSURANCE
     AGREEMENT"),   shall  remain  in  place  and  in  full  force  and  effect,
     notwithstanding  the BANK's and the OBLIGORS'  execution of this  AGREEMENT
     and the  various  agreements  of the BANK  and the  OBLIGORS  as set  forth
     herein.  MIDFA further  acknowledges and agrees that as of the date of this
     AGREEMENT,  MIDFA has  received all notices that it was required to receive
     from the BANK under and pursuant to the MIDFA INSURANCE AGREEMENT, and that
     MIDFA  does  not  have  any  defenses,  set-offs  or  counterclaims  to its
     liability  to the BANK  under the MIDFA  INSURANCE  AGREEMENT.  MIDFA  also
     acknowledges  and agrees that  pursuant to the terms and  conditions of the
     MIDFA INSURANCE AGREEMENT, MIDFA's maximum liability to the BANK thereunder
     presently  equals  and shall  hereafter  equal the lesser of: (a) the total
     amount  of the  INDEBTEDNESS  due and  owing  to the  BANK  under  the BOND
     DOCUMENTS from time to time, or (b)  $3,000,000.00.  Except as specifically
     modified herein, all other terms, covenants and conditions set forth in the
     MIDFA  INSURANCE  AGREEMENT  shall remain  unchanged  and in full force and
     effect and are hereby  ratified and  confirmed by MIDFA and the BANK in all
     respects.
       
          14. Other Terms and Covenants, Conditions: No Novation. Other than the
     foregoing,  all other terms, covenants and conditions set forth in the BOND
     DOCUMENTS shall remain  unchanged,  in full force and effect and are hereby
     ratified, acknowledged and confirmed by the OBLIGORS, MIDFA and the BANK in
     all respects,  and the OBLIGORS shall hereafter strictly comply with all of
     the  terms,  covenants  and  conditions  set  forth in the  BOND  DOCUMENTS
     including,  without limitation,  the payment terms set forth therein.  This
     AGREEMENT  and  the  various  documents  to be  executed  pursuant  to this
     AGREEMENT  shall not cause a  novation  of any of the BOND  DOCUMENTS,  nor
     shall they extinguish, affect or impair the OBLIGORS' or MIDFA's respective
     obligations  to the  BANK  under  the BOND  DOCUMENTS.  In  addition,  this
     AGREEMENT  and the,  various  documents  to be  executed  pursuant  to this
     AGREEMENT shall not release,  affect or impair the priority of any security
     interests  or liens held by the BANK  against  any  assets of the  OBLIGORS
     including, without limitation, the COLLATERAL.

          15. Governing Law. The performance and constructions of this AGREEMENT
     and the other BOND DOCUMENTS  shall be governed by the laws of the State of
     Maryland (excluding conflicts of law provisions).
        
          16. Amendment. This AGREEMENT may only be altered, modified or amended
     by a writing executed by all of the parties here-to.

          17. Time.  Time is of the essence with respect to this  AGREEMENT  and
     the terms and conditions hereof.

          18. Tense, Gender, Defined Terms, Captions, Effective Dates, Execution
     in  Counterparts  and  Via-Facsimile:  Miscellaneous.  As used herein,  the
     plural  shall refer to and  include  the  singular,  and the  singular  the
     plural,  and the use of any  gender  shall  include  and refer to any other
     gender.  All  defined  terms are  completely  capitalized  throughout  this
     AGREEMENT.  All  captions  are for the purpose of  convenience  only.  This
     AGREEMENT  shall be executed  and  delivered  by the  parties  hereto on or
     before 5:00 p.m. on May 7, 1996,  and the effective  date of this AGREEMENT
     shall be May 1, 1996.  This  AGREEMENT  may be executed  and  delivered  in
     counterparts.  Signed counterparts may be delivered via facsimile, with all
     copies  delivered  via  facsimile  to be deemed to have the same  force and
     effect as if bearing original Denatures.
    
          19. Waiver of Jury Trial. The OBLIGORS,  the BANK and MIDFA agree that
     any suit, action, or proceeding, whether claim or counterclaim,  brought or
     instituted  by or  against  any of  them,  or any of  their  successors  or
     assigns,  on or with respect to this  AGREEMENT or any other BOND DOCUMENT,
     or which In any way  relates,  directly or  indirectly,  to the  respective
     obligations of the parties hereto under any BOND DOCUMENT,  or the dealings
     of the parties with respect thereto, shall be tried by a court and not by a
     Jury. THE OBLIGORS, THE BANK AND MIDFA EXPRESSLY WAIVE ANY RIGHT TO A TRIAL
     BY JURY IN ANY  SUCH  SUIT,  ACTION  OR  PROCEEDINGS.  The  parties  hereto
     acknowledge and agree that this provision is a specific and material aspect
     of the agreement between the parties and that the BANK would not enter into
     this AGREEMENT if this provision were not contained herein.

          20.  Release of Bank.  The  OBLIGORS  jointly and  severally  release,
     acquit,  exonerate  and  forever  discharge  the  BANK,  all of the  BANK's
     affiliates,  parent corporations and subsidiaries,  all of the BANK's past,
     present and future directors,  officers,  employees,  agents and attorneys,
     and MIDFA (collectively.  the "RELEASED PARTIES"), from any and all claims,
     causes of action,  suits and damages (including claims for attorneys' fees)
     which the OBLIGORS jointly or severally ever had or now have against any or
     all of the RELEASED PARTIES, Jointly or severally.


                     (Signature and Acknowledgments Follow.)


<PAGE>


IN WITNESS  WHEREOF,  the Parties  hereto have executed this AGREEMENT as of the
date first written  above with the specific  intention of creating an instrument
under seal.


WITNESS/ATTEST:            OBLIGORS:

                           CROP GENETICS INTERNATIONAL
                                            CORPORATION,
                             A Delaware Corporation
Michael R. N. Thomas         By:     Edwin C. Quattlebaum
                          Title:     President and Chief Executive Officer
                           Date:     May 7, 1996


WITNESS/ATTEST:            BIOSYS, INC.,
                           A Delaware Corporation
Michael R. N. Thomas       By:     Edwin C. Quattlebaum
                           Title:  President and Chief Executive Officer
                           Date:   May 7, 1996


                                            MIDFA:
                                            MARYLAND INDUSTRIAL DEVELOPMENT
                                            FINANCING AUTHORITY,
                                            A Body Politic and Corporate and a
                                            Public instrumentality of the State
                                            of Maryland
                                            By:      Steven J. Lynch  (SEAL)
                                            Title:   Assistant Secretary of
                                                     Financing Programs
                                            Date:    May 13, 1996


<PAGE>


                                            BANK:

                                            THE FIRST NATIONAL BANK OF MARYLAND,
                                            A National Baking Association
Barbara Bennett                     By:     W. Blake Hampson  (SEAL)
                                            Title:   Vice President
                                            Date:    May 10, 1996


                                 ACKNOWLEDGMENTS

STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:

         I HEREBY  CERTIFY,  that on this 7th day of May,  1996,  before me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Edwin  Quattlebaum,  who  acknowledged  himself  to be the  President  and Chief
Executive  Officer  of  CROP  GENETICS  INTERNATIONAL  CORPORATION,  a  Delaware
corporation,  and who further  acknowledged that he, as such President and Chief
Executive Officer,  being authorized so to do, executed the foregoing instrument
for  the  purposes  therein  contained  by  signing  the  name  of the  Delaware
Corporation, by himself as President and Chief Executive Officer.

         IN WITNESS MY Hand and Notarial Seal.
                                            Sandra Soroka   (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
June 24, 1998



<PAGE>


STATE OF MARYLAND CITY/COUNTY OF ANNE ARUNDEL TO WIT:'

         I HEREBY  CERTIFY,  that on this 7th day of May,  1996,  before me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Edwin  Quattlebaum,  who  acknowledged  himself  to be the  President  and Chief
Executive  Officer of BIOSYS,  INC.,  a Delaware  corporation,  and who  further
acknowledged  that he, as such  President  and Chief  Executive  Officer,  being
authorized so to do, executed the foregoing  instrument for the purposes therein
contained  by  signing  the name of the  Delaware  Corporation,  by  himself  as
President and Chief Executive Officer.

         IN WITNESS MY Hand and Notarial Seal.
                                            Sandra Soroka   (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
June 24, 1998


STATE OF MARYLAND CITY/COUNTY OF BALTIMORE TO WIT:

         I HEREBY CERTIFY,  that on this 13th day of April, 1996, before me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally appeared
Stephen J. Lynch, who acknowledged himself/herself to be the Assistant Secretary
of  Financing  Programs  of  the  MARYLAND  INDUSTRIAL   DEVELOPMENT   FINANCING
AUTHORITY,  a body  politic and  corporate,  and who further  acknowledged  that
he/she, as such Assistant Secretary of Financing  Programs,  being authorized so
to do, executed the foregoing  instrument for the purposes therein  contained by
signing the name of the MARYLAND INDUSTRIAL DEVELOPMENT FINANCING AUTHORITY,  by
himself/herself as Assistant Secretary of Financing Programs.

         IN WITNESS MY Hand and Notarial Seal.
                                            Jane B. Sibez  (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
November 1, 1980


<PAGE>


STATE OF Maryland CITY/COUNTY OF Baltimore TO WIT:'

         I HEREBY  CERTIFY,  that on this 10th day of May, 1996,  before me, the
undersigned, a Notary Public of the jurisdiction aforesaid,  personally W. Blake
Hampson,  who acknowledged that he is a Vice President of First National Bank of
Maryland, a national banking association,  and who further acknowledged that he,
as such Vice  President,  being  authorized  so to do,  executed  the  foregoing
instrument  for the  purposes  therein  contained  by  signing  the  name of the
national banking association, by himself as Vice President.

         IN WITNESS MY Hand and Notarial Seal.
                                            Barbara Bennett (SEAL)
                                            NOTARY PUBLIC
My Commission Expires:
July 1, 1999

<PAGE>
THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.69 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.


IMPERIAL BANK

Special Markets Group o 2460 Sand Hill Road o Suite 102 o Menlo Park, CA 94025 o
(415) 233-3000

May 13,1996

Mr.  Michael Thomas
Vice President and Chief Financial Officer
BIOSYS
10150 Old Columbia Road
Columbia, Md. 21046-1704

Re:      Imperial Bank Loan No. 00700005672-3

Dear Mike:

With  reference to the Credit  Terms and  Conditions  dated July 26, 1995,  with
attached Commitment Letter dated July 18, 1995, (collectively refereed to as the
"Loan Agreement") between Imperial Bank ("Bank") and biosys, Inc.  ("Borrower"),
and as amended by letters dated November 14, 1995,  December 20, 1995,  February
9, 1996, in connection  with above  referenced loan ("Loan"),  Bank,  waives all
covenant  violations  contained in the loan agreement through March 31, 1996 and
to hereby modifies certain existing covenant requirements as follows:

Borrower to maintain on monthly basis unless  otherwise noted, to be measured at
April 30, 1996, and May 31, 1996; a Minimum Tangible Net Worth of $4,000,000;  a
Maximum  Total  Liabilities  to Tangible  Net Worth Ratio of 5.0:1.0;  a Minimum
Quick Ratio of 0.5:1.0;  and a Maximum Allowed Five-Month  Cumulative  Operating
Loss (measured from January 1, 1996 to May 31, 1996) of $4,000,000.

Except as modified hereby, the Loan Agreement shall remain unaltered and in full
force and effect.  This  letter  shall not  constitute  an  agreement  to future
modification  of any  covenant  or a waiver of any  future  default or breach of
covenant.

Please  sign  below to show your  agreement  with the  foregoing  and  return an
original to me.

Sincerely,

Steven D. Kattner
Vice President
Special Markets Group

Accepted and Agreed:
biosys, lnc.
By:      Michael R. N. Thomas
Title    Vice President and Chief Financial Officer
Date     May 13, 1996


THIS DOCUMENT IS A COPY OF THE EXHIBIT 10.70 FOR THE 10Q FILED ON MAY 15,
1996, PURSUANT TO A RULE 201 TEMPORARY HARDSHIP EXEMPTION.


May 13, 1996


Mr. Michael Thomas
Vice President and Chief Financial Officer
Biosys
10150 Old Columbia Road
Columbia, MD 21046-1704



Re: Lease Agreement Between Biosys and Venture Lending & Leasing, Inc., dated
December 21, 1994



Dear Mike:

VLLLI will waive the  financial  covenants in  Paragraphs 24 (d), (e) and (f) of
the above referenced  agreement and any existing amendments to them through June
30, 1996.  This waiver is  specifically  conditioned  upon the continued  waiver
through the same period by Imperial Bank of its financial covenants with Biosys.



Sincerely

Ronald W. Swenson


2010 North First Street. Suite 310 - San Jose, CA 95131
 - (408) 38-8577 - Fax (408) 36-8625


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