NANOPHASE TECHNOLOGIES CORPORATION
SC 13G, 1998-02-17
MISCELLANEOUS PRIMARY METAL PRODUCTS
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                         (Amendment No. ______________)*


                       Nanophase Technologies Corporation
                       ----------------------------------
                                (Name of Issuer)


                                  Common Stock
                         ------------------------------
                         (Title of Class of Securities)

                                     6300791
                                 --------------
                                 (CUSIP Number)


*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  2  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Venture Fund II, L.P.                                         |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Delaware                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  705,835                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  705,835                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  705,835                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.7%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  CO                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  3  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Management Partners II, L.P.                                  |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Delaware                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  719,869                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  719,869                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  719,869                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.9%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  PN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  4  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Venture Partners, L.P.                                        |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Delaware                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  719,869                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  719,869                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  719,869                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.9%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  PN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>


- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  5  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Venture Corporation                                           |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Delaware                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  719,869                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  719,869                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  719,869                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.9%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  CO                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  6  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Venture Fund, L.P.                                            |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Delaware                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  768,088                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  768,088                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  768,088                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  6.1%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  PN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  7  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  ARCH Development Corporation                                       |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  Illinois                                                           |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  768,088                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  768,088                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  768,088                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  6.1%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  CO                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  8  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  Steven Lazarus                                                     |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  USA                                                                |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  1,487,957                                        |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  1,487,957                                        |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  1,487,957                                                          |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  11.7%                                                              |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  IN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page  9  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  Keith Crandell                                                     |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  USA                                                                |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  719,869                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  719,869                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  719,869                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.9%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  IN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 10  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  Robert Nelsen                                                      |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [ ]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |  USA                                                                |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  0                                                |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |  719,869                                          |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |  0                                                |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |  719,869                                          |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  719,869                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  5.9%                                                               |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  IN                                                                 |
- --------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 11  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------



Item 1(a).  Name of Issuer: Nanophase Technologies Corp. (the "Issuer").

Item 1(b).  Address of Issuer's Principal Executive Offices: 453 Commerce
            Street, Burr Ridge, Illinois 60521.

Item 2(a).  Names of Persons Filing: ARCH Venture Fund, L.P. ("ARCH Venture
            Fund"); ARCH Development Corporation ("ARCH Development
            Corporation"); ARCH Venture Fund II, L.P. ("ARCH Venture Fund II");
            ARCH Management Partners II, L.P. ("ARCH Management Partners II");
            ARCH Venture Partners, L.P. ("ARCH Venture Partners"); ARCH Venture
            Corporation ("ARCH Venture Corporation"); Steven Lazarus, Keith
            Crandell and Robert Nelsen (collectively, the "Managing Directors").
            ARCH Venture Fund, ARCH Development Corporation, ARCH Venture Fund
            II, ARCH Management Partners II, ARCH Venture Partners, ARCH Venture
            Corporation and the Managing Directors collectively are referred to
            as the "Reporting Persons."

Item 2(b).  Address of Principal Business Office: The principal business address
            of the Reporting Persons is 8735 W. Higgins Road, Suite 235,
            Chicago, IL 60631.

Item 2(c).  Citizenship: ARCH Venture Fund, L.P., ARCH Venture Fund II, ARCH
            Management Partners II and ARCH Venture Partners are limited
            partnerships organized under the laws of the State of Delaware. ARCH
            Venture Corporation is a corporation organized under the laws of the
            State of Delaware. ARCH Development Corporation is a corporation
            organized under the laws of the State of Illinois. Each Managing
            Director is a US citizen.

Item 2(d).  Title of Class of Securities: Common Stock, $.01 (the "Common
            Stock").

Item 2(e).  CUSIP Number:  630079101.

Item 3.     If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b),
            -------------------------------------------------------------------
            check whether the person filing is a:
            ------------------------------------

                 (a)  [ ] Broker or Dealer registered under Section 15 of
                          the Securities Exchange Act of 1934 (the "Act").

                 (b)  [ ] Bank as defined in Section 3(a)(6) of the Act.

                 (c)  [ ] Insurance Company as defined in Section
                          3(a)(19) of the Act.

                 (d)  [ ] Investment Company registered under Section 8
                          of the Investment Company Act of 1940.

                 (e)  [ ] Investment Adviser registered under Section 203
                          of the Investment Advisers Act of 1940.

                 (f)  [ ] Employee Benefit Plan, Pension Fund which is
                          subject to the provisions of the Employee
                          Retirement Income Security Act of 1974 or Endowment
                          Fund; see Rule 13d-1(b)(1)(ii)(F) of the Act.
<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 12  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

                 (g)  [ ] Parent Holding Company, in accordance with Rule
                          13d-1(b)(ii)(G) of the Act.

                 (h)  [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(H)
                          of the Act.

               Not Applicable.

Item 4.        Ownership:
               ---------

               (a)    Amount Beneficially Owned: As of December 31, 1997: ARCH
                      Venture Fund II is the record owner of 705,835 shares of
                      Common Stock; ARCH II Parallel Fund is the record owner of
                      14,034 shares of Common Stock; and ARCH Venture Fund is
                      the record owner of 366,550 shares of Common Stock and a
                      presently exercisable warrant (the "Warrant") to purchase
                      up to an aggregate of 401,538 shares of Common Stock.

                      ARCH Management Partners II is the sole general partner of
                      ARCH Venture Fund II and ARCH II Parallel Fund. ARCH
                      Venture Partners is the sole general partner of ARCH
                      Management Partners II. ARCH Venture Corporation is the
                      sole general partner of ARCH Venture Partners. Each of
                      ARCH Management Partners II, ARCH Venture Partners and
                      ARCH Venture Corporation may be deemed to beneficially own
                      an aggregate of 719,869 shares of Common Stock held by
                      ARCH Venture Fund II and ARCH II Parallel Fund. The
                      Managing Directors are the managing directors of ARCH
                      Venture Corporation and may be deemed to beneficially own
                      the shares of Common Stock held by ARCH Venture Fund II
                      and ARCH II Parallel Fund. The Managing Directors disclaim
                      beneficial ownership with respect to these shares.

                      ARCH Development Corporation is the general partner of
                      ARCH Venture Fund and may be deemed to beneficially own
                      768,088 shares of Common Stock. Mr. Lazarus has been
                      granted power of attorney to act in the name of and for
                      ARCH Development Corporation with respect to the role of
                      ARCH Development Corporation as general partner of ARCH
                      Venture Fund and therefore may be deemed to beneficially
                      own the securities held by ARCH Venture Fund. Mr. Lazarus
                      disclaims beneficial ownership of these shares.

               (b)    Percent of Class: ARCH Venture Fund, 6.1%; ARCH
                      Development Corporation, 6.1%; ARCH Venture Fund II, 5.7%;
                      ARCH Management Partners II, 5.9%; ARCH Venture Partners,
                      5.9%; ARCH Venture Corporation, 5.9%; Steven Lazarus,
                      11.7%; Keith Crandell, 5.9%; and Robert Nelsen, 5.9%. The
                      foregoing percentages are calculated based on the
                      12,277,454 shares of Common Stock reported in the Issuer's
                      Prospectus dated November 26, 1997 to be outstanding after
                      the Issuer's Initial Public Offering.

<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 13  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------


               (c)    Number of Shares as to Which Such Person Has:
                      --------------------------------------------

                      (i) Sole power to vote or to direct the vote: ARCH Venture
                      Fund, 0; ARCH Development Corporation, 0; ARCH Venture
                      Fund II, 0; ARCH Management Partners II, 0; ARCH Venture
                      Partners, 0; ARCH Venture Corporation, 0; Steven Lazarus,
                      0; Keith Crandell, 0; and Robert Nelsen, 0.

                      (ii) Shared power to vote or to direct the vote: ARCH
                      Venture Fund, 768,088; ARCH Development Corporation,
                      768,088; ARCH Venture Fund II, 705,835; ARCH Management
                      Partners II, 719,869; ARCH Venture Partners, 719,869; ARCH
                      Venture Corporation, 719,869; Steven Lazarus, 1,487,957;
                      Keith Crandell, 719,869; and Robert Nelsen, 719,869.

                      (iii) Sole power to dispose or to direct the disposition
                      of: ARCH Venture Fund, 0; ARCH Development Corporation, 0;
                      ARCH Venture Fund II, 0; ARCH Management Partners II, 0;
                      ARCH Venture Partners, 0; ARCH Venture Corporation, 0;
                      Steven Lazarus, 0; Keith Crandell, 0; and Robert Nelsen,
                      0.

                      (iv) Shared power to dispose or to direct the disposition
                      of: ARCH Venture Fund, 768,088; ARCH Development
                      Corporation, 768,088; ARCH Venture Fund II, 705,835; ARCH
                      Management Partners II, 719,869; ARCH Venture Partners,
                      719,869; ARCH Venture Corporation, 719,869; Steven
                      Lazarus, 1,487,957; Keith Crandell, 719,869; and Robert
                      Nelsen, 719,869.

Item 5.        Ownership of Five Percent or Less of a Class:
               --------------------------------------------

               Not Applicable.

Item 6.        Ownership of More than Five Percent on Behalf of Another Person:
               ---------------------------------------------------------------

               Not Applicable.

Item 7.        Identification and Classification of the Subsidiary Which
               ---------------------------------------------------------
               Acquired the Security Being Reported on By the Parent Holding
               -------------------------------------------------------------
               Company:
               -------

               Not Applicable.

Item 8.        Identification and Classification of Members of the Group:
               ---------------------------------------------------------
               ARCH Venture Fund II, ARCH II Parallel Fund, ARCH Management
               Partners II, ARCH Venture Partners, ARCH Venture Corporation, the
               Managing Directors, ARCH Venture Fund, and ARCH Development
               Corporation expressly disclaim membership in a "group" as defined
               in Rule 13d-5(b)(1).

<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 14  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

Item 9.        Notice of Dissolution of Group:
               ------------------------------
               Not Applicable.

Item 10.       Certification:
               -------------
               Not Applicable. This statement on Schedule 13G is not filed
               pursuant to Rule 13d-1(b).


<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 15  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

                                    SIGNATURE
                                    ---------

        After reasonable inquiry and to the best of its knowledge and belief,
each of the undersigned certifies that the information set forth in this
statement is true, complete and correct.

Dated:  February 12, 1998    ARCH VENTURE FUND II, L.P.

                             By:    ARCH Management Partners II, L.P.
                                    its General Partner

                                    By:    ARCH Venture Partners, L.P.
                                           its General Partner

                                           By:    ARCH Venture Corporation
                                                  its General Partner

                                                  By:  /s/ Steven Lazarus
                                                       ------------------
                                                       Managing Director

                             ARCH MANAGEMENT PARTNERS II, L.P.

                             By:    ARCH Venture Partners, L.P.
                                    its General Partner

                                    By:    ARCH Venture Corporation
                                           its General Partner

                                           By:  /s/ Steven Lazarus
                                                ------------------
                                                Managing Director

                             ARCH VENTURE PARTNERS, L.P.

                             By:    ARCH Venture Corporation
                                    its General Partner

                                    By:  /s/ Steven Lazarus
                                         ------------------
                                         Managing Director

                             ARCH VENTURE CORPORATION

                             By:  /s/ Steven Lazarus
                                  ------------------
                                  Managing Director


<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 16  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

                             ARCH VENTURE FUND, L.P.

                             By:    ARCH Development Corporation
                                    its General Partner


                                    By:  /s/ Steven Lazarus
                                         ------------------
                                         Steven Lazarus

                                    Its: Agent and Attorney In Fact

                             ARCH DEVELOPMENT CORPORATION


                             By:    /s/ Steven Lazarus
                                    ------------------
                                    Steven Lazarus

                             Its: Agent and Attorney In Fact


                             /s/ Steven Lazarus
                             ------------------
                             Steven Lazarus


                             /s/ Keith Crandell
                             ------------------
                             Keith Crandell


                             /s/ Robert Nelsen
                             ------------------
                             Robert Nelsen




<PAGE>

- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 17  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

                                                                      Exhibit 1
                                                                      ---------

                                    AGREEMENT
                                    ---------

        Pursuant to Rule 13d-1-(f)(1) under the Securities Exchange Act of 1934,
the undersigned hereby agree that only one statement containing the information
required by Schedule 13G need be filed with respect to the ownership by each of
the undersigned of shares of stock of Nanophase Technologies Corporation.

        This Agreement may be executed in any number of counterparts, each of
which shall be deemed an original.

Dated:  February 12, 1998       ARCH VENTURE FUND II, L.P.

                                By:     ARCH Management Partners II, L.P.
                                        its General Partner

                                        By:    ARCH Venture Partners, L.P.
                                               its General Partner

                                               By:    ARCH Venture Corporation
                                                      its General Partner

                                                      By:  /s/ Steven Lazarus
                                                           ------------------
                                                           Managing Director

                                        ARCH MANAGEMENT PARTNERS II, L.P.

                                        By:    ARCH Venture Partners, L.P.
                                               its General Partner

                                               By:    ARCH Venture Corporation
                                                      its General Partner

                                                      By:  /s/ Steven Lazarus
                                                           ------------------
                                                           Managing Director

                                        ARCH VENTURE PARTNERS, L.P.

                                        By:    ARCH Venture Corporation
                                               its General Partner

                                               By: /s/ Steven Lazarus
                                                   ------------------
                                                   Managing Director

                                        ARCH VENTURE CORPORATION

                                        By:  /s/ Steven Lazarus
                                             ------------------
                                             Managing Director
<PAGE>
- -------------------------                           ---------------------------
|CUSIP NO.  6300791     |           13G            |   Page 18  of  18  Pages |
|          -----------  |                          |        ---     ---       |
- -------------------------                           ---------------------------

                                        ARCH VENTURE FUND, L.P.

                                        By:    ARCH Development Corporation
                                               its General Partner

                                               By: /s/ Steven Lazarus
                                                   ------------------
                                                   Steven Lazarus

                                               Its: Agent and Attorney In Fact

                                        ARCH DEVELOPMENT CORPORATION


                                        By: /s/ Steven Lazarus
                                                ------------------
                                                Steven Lazarus

                                        Its: Agent and Attorney In Fact


                                        /s/ Steven Lazarus
                                        ------------------
                                        Steven Lazarus

                                        /s/ Keith Crandell
                                        ------------------
                                        Keith Crandell

                                        /s/ Robert Nelsen
                                        ------------------
                                        Robert Nelsen


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