NEOZYME II CORP
SC 13G/A, 1996-11-12
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>
 
                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549


                                 SCHEDULE 13G
                 Under the Securities and Exchange Act of 1934
                                Amendment No. 5


                            Neozyme II Corporation
                        -------------------------------
                               (Name of Issuer)



                                     Units
                                 ------------
                        (Title of Class of Securities)



                                   G6420H112
                                 ------------
                                (CUSIP Number)



     Check the following box if a fee is being paid with this statement _______.
     (A fee is not required only if the filing person:  (1) has a previous
     statement on file reporting beneficial ownership of more than five percent
     of the class of securities described in item 1: and (2) has filed no
     amendment subsequent thereto reporting beneficial ownership of five percent
     or less of such class.)  (See Rule 13d-7.)



                         (Continued on following pages)

                               Page 1 of 5 Pages
<PAGE>
 
- ----------------
CUSIP NO.
G6420H112
- ----------------
- --------------------------------------------------------------------------------
1.   Name of Reporting Person
     S.S. or  I.R.S. Identification No. of  Above Person

     The Goldman Sachs Group, L.P.
- --------------------------------------------------------------------------------
2.   Check the Appropriate Box if a Member of a Group

                                         (a) _____
                                         (b) _____
- --------------------------------------------------------------------------------
3.   SEC Use Only

- --------------------------------------------------------------------------------
4.   Citizenship or place of  Organization
 
         Delaware
- --------------------------------------------------------------------------------
Number of       5  Sole Voting Power
Shares
Beneficially           0
                -------------------------
Owned By        6  Shared Voting Power
Each
Reporting              0
                -------------------------
Person With     7  Sole Dispositive Power

                       0
                -------------------------
               8    Shared Dispositive Power

                       0
                -------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

       0
- --------------------------------------------------------------------------------
10.  Check if the Aggregate Amount in Row (9) Excludes Certain Shares

- --------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)

       0.0%
- --------------------------------------------------------------------------------
12.  Type of Reporting Person

       HC-PN
- --------------------------------------------------------------------------------

                               Page 2 of 5 Pages
<PAGE>
 
- -------------------
CUSIP NO.
G6420H112
- -------------------
- --------------------------------------------------------------------------------
1.   Name of Reporting Person
     S.S. or I.R.S. Identification No. of Above Person

     Goldman, Sachs & Co.
- --------------------------------------------------------------------------------
2.   Check the Appropriate Box if a Member of a Group

                                         (a) _____
                                         (b) _____
- --------------------------------------------------------------------------------
3.   SEC Use Only

- --------------------------------------------------------------------------------
4.   Citizenship or place of Organization
 
         New York
- --------------------------------------------------------------------------------
Number of       5  Sole Voting Power
Shares
Beneficially           0
                -------------------------
Owned By        6  Shared Voting Power
Each
Reporting              0
                -------------------------
Person With     7  Sole Dispositive Power

                       0
                -------------------------
               8    Shared Dispositive Power

                       0
                -------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

        0
- --------------------------------------------------------------------------------
10.  Check if the Aggregate Amount in Row (9) Excludes Certain Shares

- --------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)

        0.0%
- --------------------------------------------------------------------------------
12.  Type of Reporting Person
        BD-PN-IA
- --------------------------------------------------------------------------------

                               Page 3 of 5 Pages
<PAGE>
 
     Item 4.     Ownership.

           (a).  Amount beneficially owned:
                 See the responses(s) to Item 9 on the attached cover pages(s).

           (b).  Percent of class:
                 See the response(s) to Item 11 on the attached cover pages(s).

           (c).  Number of shares as to which such person has:

                 (i)    Sole power to vote or to direct the vote:
                             See the response(s) to Item 5 on the attached cover
                             page(s).

                 (ii)   Shared power to vote or direct the vote:
                             See the response(s) to Item 6 on the attached cover
                             page(s).

                 (iii)  Sole power to dispose or to direct the disposition of:
                             See the response(s) to Item 7 on the attached cover
                             page(s).

                 (iv)   Shared power to dispose or to direct the disposition of:
                             See the response(s) to Item 8 on the attached cover
                             page(s).

     Item 5.   Ownership of Five Percent or Less of a Class.
                             October 21, 1996

 
     Item 10.  Certification.

               By signing below I certify that, to the best of my knowledge and
               belief, the securities referred to above were acquired in the
               ordinary course of business and were not acquired for the purpose
               of and do not have the effect of changing or influencing the
               control of the issuer of such securities and were not acquired in
               connection with or as a participant in any transaction having
               such purpose or effect.

                               Page 4 of 5 Pages
<PAGE>
 
                                   SIGNATURE

          After reasonable inquiry and to the best of my knowledge and belief, I
          certify that the information set forth in this statement is true,
          complete and correct.



Date:  November 10, 1996


                              THE GOLDMAN SACHS GROUP, L.P.


                              By:   /s/ Eric M. Mindich
                                  -------------------------------------
                              Name:   Eric M. Mindich
                              Title:   General Partner


                              GOLDMAN, SACHS & CO.


                              By:  /s/ Eric M. Mindich
                                  -------------------------------------
                              Name:    Eric M. Mindich
                              Title:   General Partner

                               Page 5 of 5 Pages


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