ARIAD PHARMACEUTICALS INC
SC 13G/A, 2000-02-15
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                 SCHEDULE 13G/A

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                                (AMENDMENT NO.1)*

                           ARIAD PHARMACEUTICALS, INC.
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                     COMMON STOCK, PAR VALUE $.001 PER SHARE
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    04033A100
                            -------------------------
                                 (CUSIP Number)

- --------------------------------------------------------------------------------
              (Date of Event Which Requires Filing This Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     [ ] Rule 13d-1(b)

     [X] Rule 13d-1(c)

     [ ] Rule 13d-1(d)

  *The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed " for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                                Page 1 of 8 pages


<PAGE>   2



CUSIP No.     04033A100
- --------------------------------------------------------------------------------

           1.    Names of Reporting Persons.

                 I.R.S. Identification Nos.  of above persons (entities only).

                 BB BIOTECH AG

- --------------------------------------------------------------------------------

           2.    Check the Appropriate Box if a Member of a Group (See
                 Instructions)

                 (a)

                 (b)

- --------------------------------------------------------------------------------

           3.    SEC  Use Only

- --------------------------------------------------------------------------------

           4.    Citizenship or Place of Organization
                          Switzerland

- --------------------------------------------------------------------------------
     Number of          5.   Sole Voting Power
     Shares Bene-
     ficially by                         -0-
     Owned by Each
     Reporting           -------------------------------------------------------
     Person With:
                        6.   Shared Voting Power

                                         -0-

                         -------------------------------------------------------

                        7.   Sole Dispositive Power

                                         -0-

                         -------------------------------------------------------

                        8.   Shared Dispositive Power

                                         -0-

- --------------------------------------------------------------------------------
           9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                 -0-

           10.   Check if the Aggregate Amount in Row (11) Excludes Certain
                 shares

           11.   Percent of Class Represented by amount in Row (11)

                 0%

- --------------------------------------------------------------------------------
           12.   Type of Reporting Person (See Instructions)            HC, CO

- --------------------------------------------------------------------------------

                                Page 2 of 8 pages

<PAGE>   3

CUSIP No. 04033A100

- --------------------------------------------------------------------------------

           1.    Names of Reporting Persons.

                 I.R.S. Identification Nos.  of above persons (entities only).

                 BIOTECH TARGET S.A.

- --------------------------------------------------------------------------------

           2.    Check the Appropriate Box if a Member of a Group
                 (a)
                 (b)

- --------------------------------------------------------------------------------

           3.    SEC  Use Only

- --------------------------------------------------------------------------------

           4.    Citizenship or Place of Organization

                         PANAMA

- --------------------------------------------------------------------------------
 Number of                5.   Sole Voting Power
 Shares Bene-                            -0-
 ficially by              ------------------------------------------------------
 Owned by Each            6.   Shared Voting Power
 Reporting
 Person With:                            -0-

                          ------------------------------------------------------

                          7.   Sole Dispositive Power

                                         -0-

                          ------------------------------------------------------

                          8.   Shared Dispositive Power

                                         -0-

- --------------------------------------------------------------------------------

           9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                    -0-

           10.   Check if the Aggregate Amount in Row (11) Excludes Certain
                 shares

           11.   Percent of Class Represented by amount in Row (11)

                    0%

- --------------------------------------------------------------------------------
           12.   Type of Reporting Person

                    CO

- --------------------------------------------------------------------------------


                                Page 3 of 8 pages


<PAGE>   4



CUSIP No. 04033A100
- --------------------------------------------------------------------------------

ITEM 1.

     (a)   Name of Issuer
                 Ariad Pharmaceuticals, Inc.

     (b)   Address of Issuer's Principal Executive Offices
                 26 Landsdowne Street
                 Cambridge, Massachusetts 02139-4234

ITEM 2.

     (a)   Name of Person Filing
                 BB Biotech AG ("BB Biotech")
                 Biotech Target S.A.  ("Biotech Target")

     (b)   Address of Principal Business Office or, if none, Residence

                 BB Biotech                         Biotech Target
                 Vordergasse 3                      Swiss Bank Tower
                 8200 Schaffhausen                  Panama 1
                 CH/Switzerland                     Republic of  Panama

     (c)   Citizenship
                 See Item No. 4 of cover pages.

     (d)   Title of Class of Securities
                 Common Stock, Par Value $.001 Per Share

     (e)   CUSIP Number
                 04033100

ITEM 3.    IF THIS STATEMENT IS FILED PURSUANT TO SECTIONS 240.13D-1(B) OR
           240.13D-2(B) OR (C), CHECK WHETHER THE PERSON FILING IS A:

     (a)   [ ] Broker or dealer registered under section 15 of the Act
               (15 U.S.C. 78o).

     (b)   [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

     (c)   [ ] Insurance company as defined in section 3(a)(19) of the Act
               (15 U.S.C. 78c).

                                Page 4 of 8 pages


<PAGE>   5



CUSIP No. 04033A100
- --------------------------------------------------------------------------------

     (d)   [ ] Investment company registered under section 8 of the
               Investment Company Act of 1940 (15 U.S.C. 80a-8).

     (e)   [ ] An investment adviser in accordance with Section
               240.13d-1(b) (1)(ii)(E);

     (f)   [ ] An employee benefit plan or endowment fund in accordance
               with Section 240.13d-1(b)(1)(ii)(F);

     (g)   [ ] A parent holding company or control person in accordance
               with Section 240.13d-1(b)(1)(ii)(G);

     (h)   [ ] A savings associations as defined in Section 3(b) of the
               Federal Deposit Insurance Act (12 U.S.C. 1813);

     (i)   [ ] A church plan that is excluded from the definition of an
               investment company under section 3(c)(14) of the Investment
               Company Act of 1940 (15 U.S.C. 80a-3);

     (j)   [ ] Group, in accordance with Section 240.13d-1(b)(1)(ii)(J).

ITEM 4.   OWNERSHIP

     Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

     (a)    Amount beneficially owned:
                 -0-

     (b)   Percent of class:
                 0%

     (c) Number of shares as to which the person has:

                 (i)           Sole power to vote or to direct the vote
                               -0-

                 (ii)          Shared power to vote or to direct the vote
                               -0-

                 (iii)         Sole power to dispose or to direct the
                               disposition of
                               -0-

                                Page 5 of 8 pages


<PAGE>   6



CUSIP No. 04033A100

- --------------------------------------------------------------------------------

                 (iv)          Shared power to dispose or to direct the
                               disposition of
                               -0-

ITEM 5.   OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

     If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following [X].

ITEM 6.    OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

     Not applicable.

ITEM 7.   IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
          SECURITY BEING  REPORTED ON BY THE PARENT HOLDING COMPANY

     This statement is filed jointly by BB Biotech AG and Biotech Target S.A.
Biotech Target is a wholly-owned subsidiary of BB Biotech.

 ITEM 8.   IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

     Not applicable.

ITEM 9.

     Not applicable.

ITEM 10.  CERTIFICATION

     By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were not acquired and are not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.

                                Page 6 of 8 pages


<PAGE>   7



CUSIP No. 04033A100
- --------------------------------------------------------------------------------


                                   SIGNATURES

     After reasonable inquiry and the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

                                         BB BIOTECH AG

Date: February 14, 2000                  By:    /s/ N. FREY
                                                ----------------------
                                         Name:  N. Frey
                                                -----------------------


Date: February 14, 2000                  By:    /s/ D. RACNJAK
                                                -----------------------
                                         Name:  D. Racnjak
                                                -----------------------

                                                -----------------------


                                         BIOTECH TARGET, S.A.

Date: February 14, 2000                  By:    /s/ N. FREY
                                                -----------------------
                                         Name:  N. Frey
                                                -----------------------

                                                -----------------------


Date: February 14, 2000                  By:    /s/ D. RACNJAK
                                                ----------------------
                                         Name:  D. Racnjak
                                                ----------------------

                                                ----------------------




                                Page 7 of 8 pages


<PAGE>   8



CUSIP No. 04033A100

- --------------------------------------------------------------------------------


                                  EXHIBIT INDEX

                                  -------------

Exhibit 1: Agreement by and between BB Biotech and Biotech Target with
           respect to the filing of this disclosure statement.*

- ---------------------
* Previously filed.

                                Page 8 of 8 pages


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