SUNPHARM CORPORATION
PRE 14A, 1999-04-26
PHARMACEUTICAL PREPARATIONS
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                            SCHEDULE 14A INFORMATION

PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934
                                (AMENDMENT NO. )

Filed by the Registrant [X]

Filed by a Party other than the Registrant [ ]

Check the appropriate box:

[X]  Preliminary Proxy Statement

[ ]  Confidential,  for  Use  of the  Commission  Only  (as  permitted  by  Rule
     14a-6(e)(2))

[ ]  Definitive Proxy Statement

[ ]  Definitive Additional Materials

[ ]  Soliciting Material Pursuant to ' 240.14a-118 or  ' 240.14a-12

                              SUNPHARM CORPORATION
                (NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)


     (NAME OF PERSON(S) FILING PROXY STATEMENT IF OTHER THAN THE REGISTRANT)

Payment of Filing Fee (Check the appropriate box):

[X]  No fee required.

[ ]  Fee computed on table below per Exchange Act Rules 14a-6(I)(4) and 0-11.

     1)  Title of each class of securities to which transaction applies:

         -----------------------------------------------------------------------

     2)  Aggregate number of securities to which transaction applies:

         -----------------------------------------------------------------------

     3)  Per unit  price  or other  underlying  value  of  transaction  computed
         pursuant to  Exchange  Act Rule 0-11 (Set forth the amount on which the
         filing fee is calculated and state how it was determined):

         -----------------------------------------------------------------------

     4)  Proposed maximum aggregate value of transaction:

         -----------------------------------------------------------------------

     5)  Total fee paid:

         -----------------------------------------------------------------------

[ ]      Fee paid previously with preliminary materials.

[ ]      Check box if any part of the fee is offset as provided by Exchange  Act
Rule  0-11(a)(2)  and identify the filing for which the  offsetting fee was paid
previously.  Identify the previous filing by registration  statement  number, or
the Form or Schedule and the date of its filing.

     1)  Amount Previously Paid:


     2)  Form, Schedule or Registration Statement No.:



     3)  Filing Party:



     4)  Date Filed:

<PAGE>


                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                             TO BE HELD MAY 25, 1999


To the Stockholders of SunPharm Corporation:

         The Annual Meeting of Stockholders  (the "Annual  Meeting") of SunPharm
Corporation (the "Company") will be held on Tuesday, May 25, 1999, at 9:00 a.m.,
local time,  at the Orlando  Hyatt  Regency  Airport,  Orlando,  Florida for the
following purposes:

         1.       To elect seven  directors of the Company,  each to serve until
         the  Company's  next  Annual  Meeting of  Stockholders  or until  their
         respective successors have been duly elected and qualified;

         2.       To approve the issuance in a private placement of Common Stock
         of the Company  (and  securities  exercisable  for such  Common  Stock)
         representing 20% or more of the number of issued and outstanding shares
         of such Common Stock;

         3.       To ratify and approve the appointment of Deloitte & Touche LLP
         as the Company's  independent  public  accountants  for its fiscal year
         ending December 31, 1999; and

         4.       To act upon such other  business as may  properly  come before
         the meeting or any adjournments thereof.

         Only  stockholders of record at the close of business on April 26, 1999
will be entitled to notice of and to vote at the Annual Meeting.

         It is important  that your shares be  represented at the Annual Meeting
regardless of whether you plan to attend. THEREFORE,  PLEASE MARK, SIGN AND DATE
THE  ENCLOSED  PROXY AND  RETURN IT IN THE  ACCOMPANYING  POSTPAID  ENVELOPE  AS
PROMPTLY AS POSSIBLE.  If you are present at the Annual Meeting,  and wish to do
so, you may revoke the proxy and vote in person.

                                        By  Order of the Board of Directors,




                                        Cecilia Bryant
                                        SECRETARY

Jacksonville, Florida
May 6, 1999

<PAGE>

                              SUNPHARM CORPORATION
                             THE VERANDA, SUITE 301
                                 814 HIGHWAY A1A
                        PONTE VEDRA BEACH, FLORIDA 32082




                                   May 6, 1999



TO OUR STOCKHOLDERS:

       You  are  cordially   invited  to  attend  the  1999  Annual  Meeting  of
Stockholders  of SunPharm  Corporation  to be held on Tuesday,  May 25, 1999, at
9:00 a.m., local time, at the Orlando Hyatt Regency Airport, Orlando, Florida. A
Notice of the Annual  Meeting,  Proxy  Statement  and form of proxy are enclosed
with this letter.

       We  encourage  you to read the  Notice of the  Annual  Meeting  and Proxy
Statement  so that you may be  informed  about the  business  to come before the
meeting.  Your participation in the Company's business is important,  regardless
of the number of shares  that you hold.  To ensure  your  representation  at the
meeting,  please  promptly  sign and return the  accompanying  proxy card in the
postage-paid envelope.

        We look forward to seeing you on May 25, 1999.


                                       Sincerely,




                                       Stefan Borg
                                       PRESIDENT AND CHIEF EXECUTIVE OFFICER


<PAGE>

                              SUNPHARM CORPORATION
                             THE VERANDA, SUITE 301
                                 814 HIGHWAY A1A
                        PONTE VEDRA BEACH, FLORIDA 32082

                                   ----------

                                 PROXY STATEMENT
                                       FOR
                         ANNUAL MEETING OF STOCKHOLDERS


                             TO BE HELD MAY 25, 1999



                    SOLICITATION AND REVOCABILITY OF PROXIES

         The  accompanying  Proxy is  solicited  by the  Board of  Directors  of
SunPharm  Corporation  (the  "Company"),  to be voted at the  Annual  Meeting of
Stockholders  of the  Company to be held on Tuesday,  May 25, 1999 (the  "Annual
Meeting"),  at 9:00 a.m.,  local time,  at the Orlando  Hyatt  Regency  Airport,
Orlando, Florida, for the purpose set forth in the accompanying Notice of Annual
Meeting of Stockholders, and at any adjournment(s) of the Annual Meeting. If the
accompanying  Proxy is properly executed and returned,  the shares it represents
will be voted at the Annual  Meeting in  accordance  with the  directions  noted
thereon  or,  if no  direction  is  indicated,  it will be voted in favor of the
proposals  described in this Proxy  Statement.  In addition,  the Proxy  confers
discretionary  authority  to the persons  named in the Proxy  authorizing  those
persons to vote, in their discretion, on any other matters properly presented at
the Annual  Meeting.  The Board of Directors is not currently  aware of any such
other matters.

         Each stockholder of the Company has the  unconditional  right to revoke
his Proxy at any time  prior to its  exercise,  either  in person at the  Annual
Meeting or by written  notice to the Company  addressed to  Secretary,  SunPharm
Corporation, The Veranda, Suite 301, 814 Highway A1A, Ponte Vedra Beach, Florida
32082. No revocation by written notice will be effective  unless such notice has
been  received by the  Secretary  of the Company  prior to the day of the Annual
Meeting or by the inspector of election at the Annual Meeting.

         The  principal  executive  offices of the  Company  are  located at The
Veranda,  Suite 301, 814 Highway A1A,  Ponte Vedra Beach,  Florida  32082.  This
Proxy  Statement and the  accompanying  Notice of Annual Meeting of Stockholders
and Proxy are being  mailed  to the  Company's  stockholders  on or about May 6,
1999.

         In  addition  to the  solicitation  of  proxies  by use of  this  Proxy
Statement,  directors,  officers  and  employees  of the Company may solicit the
return of proxies by mail, personal interview,  telephone or telegraph. Officers
and employees of the Company will not receive additional  compensation for their
solicitation efforts, but they will be reimbursed for any out-of-pocket expenses
incurred.  Brokerage houses and other custodians,  nominees and fiduciaries will
be requested, in connection with the stock registered in their names, to forward
solicitation materials to the beneficial owners of such stock.

         All costs of preparing,  printing, assembling and mailing the Notice of
Annual Meeting of Stockholders, this Proxy Statement, the enclosed form of Proxy
and any  additional  materials,  as well as the cost of forwarding  solicitation
materials to the beneficial owners of stock and all other costs of solicitation,
will be borne by the Company.

<PAGE>

                             PURPOSES OF THE MEETING

         At the Annual  Meeting,  the  Company's  stockholders  will be asked to
consider and act upon the following matters:

         1.       The election of seven directors of the Company,  each to serve
                  until the Company's  next Annual  Meeting of  Stockholders  or
                  until their  respective  successors have been duly elected and
                  qualified;

         2.       To approve the issuance in a private placement of Common Stock
                  of the Company  (and  securities  exercisable  for such Common
                  Stock)  representing  20% or more of the  number of issued and
                  outstanding shares of such Common Stock;

         3.       A proposal to ratify and approve the appointment of Deloitte &
                  Touche LLP as the Company's independent public accountants for
                  its fiscal year ending December 31, 1999; and

         4.       Such other business as may properly come before the meeting or
                  any adjournments thereof.


                                QUORUM AND VOTING

         The close of  business  on April 26,  1999 has been fixed as the record
date (the "Record Date") for the determination of stockholders  entitled to vote
at the Annual Meeting and any adjournment(s) thereof. As of the Record Date, the
Company had issued and  outstanding  (i) 6,922,518  shares of common stock,  par
value $.0001 per share (the  "Common  Stock"),  (ii) 300,000  shares of Series A
Redeemable  Convertible Preferred Stock, par value $.001 and (iii) 66,667 shares
of Series B  Redeemable  Convertible  Preferred  Stock,  par value  $.001.  Each
stockholder  of record of Common Stock will be entitled to one vote per share on
each matter that is called to vote at the Annual  Meeting.  Shares of  Preferred
Stock have  voting  rights on all  matters  subject to a vote of the  holders of
Common Stock on an  as-converted  basis.  As of the Record  Date,  the shares of
Preferred  Stock are entitled to an aggregate of 366,667  votes upon each of the
matters to be voted on at the Annual Meeting. The total number of votes that may
be cast at the Annual Meeting is 7,289,185.

         The presence, either in person or by proxy, of holders of a majority of
the  outstanding  shares of Common Stock is necessary to  constitute a quorum at
the Annual Meeting. Abstentions and broker non-votes are counted for purposes of
determining  whether a quorum is present.  A plurality  vote is required for the
election  of  directors.  Accordingly,  if a quorum  is  present  at the  Annual
Meeting,  the seven  persons  receiving  the  greatest  number of votes  will be
elected  to serve as  directors.  Withholding  authority  to vote for a director
nominee and broker  non-votes in the  election of directors  will not affect the
outcome of the election of  directors.  All other matters to be voted on will be
decided  by the vote of the  holders  of a  majority  of the  shares  present or
represented  at the Annual  Meeting and entitled to vote on such matter.  On any
such matter,  an  abstention  will have the same effect as a negative  vote but,
because  shares  held by  brokers  will not be  considered  entitled  to vote on
matters as to which the brokers withhold authority,  a broker non-vote will have
no effect on such vote.

         All Proxies that are properly  completed,  signed and returned prior to
the  Annual  Meeting  will be voted.  Any Proxy  given by a  stockholder  may be
revoked at any time before it is  exercised by the  stockholder  (i) filing with
the  Secretary  of the Company an  instrument  revoking it, (ii)  executing  and
returning a Proxy bearing a later date or (iii) attending the Annual Meeting and
expressing a desire to vote his shares of Common Stock in person.  Votes will be
counted by Continental  Stock Transfer & Trust Company,  the Company's  transfer
agent and registrar.

                                      -2-

<PAGE>

                               PROPOSAL NUMBER 1:
                              ELECTION OF DIRECTORS

         The  Board of  Directors  has  nominated  and urges you to vote for the
election of the seven  nominees  identified  below,  who have been  nominated to
serve as  directors  for a  one-year  term or until  their  successors  are duly
elected and  qualified.  Each of the  nominees  listed  below is a member of the
Company's present Board of Directors. Proxies solicited hereby will be voted for
all of the nominees unless stockholders specify otherwise in their Proxies.

         If, at the time of or prior to the Annual Meeting,  any of the nominees
should be unable or decline to serve, the  discretionary  authority  provided in
the Proxy may be used to vote for a substitute or substitutes  designated by the
Board of  Directors.  The Board of  Directors  has no reason to believe that any
substitute nominee or nominees will be required.

NOMINEES FOR ELECTION AS DIRECTORS

         The seven  nominees for election as  directors  and certain  additional
information with respect to each of them, are as follows:

<TABLE>
<CAPTION>
                                                                                        Year First
       Name                           Age          Position With the Company         Became a Director
       ----                           ---          -------------------------         -----------------
<S>                                  <C>      <C>                                            <C> 
Stefan Borg (1)                       45      President and Chief Executive Officer,       1991
                                              Director
Philip R. Tracy (2)                   57      Chairman of the Board of Directors           1995
Charles L. Dimmler  III (1)           57      Director                                     1997
Jerry T. Jackson                      57      Director                                     1996
Robert S. Janicki, M.D. (3)(4)        64      Director, Member of the Pharmaceutical       1991
                                              Advisory Board
Jay Moorin(1) (2)                     48      Director                                     1997
Robert A. Schoellhorn (3)(4)          70      Director                                     1992
</TABLE>

- ----------
(1)      Member of the Nominating Committee
(2)      Member of the Audit Committee
(3)      Member of the Compensation Committee
(4)      Member of the Option Committee

STEFAN BORG
PRESIDENT AND CHIEF EXECUTIVE OFFICER, DIRECTOR

         Mr. Borg founded the Company and has been President and Chief Executive
Officer of the  Company  since its  inception  and was  Chairman of the Board of
Directors of the Company from inception  until January 1995. From September 1991
to August 1993, Mr. Borg was a general  partner of Batterson,  Johnson & Borg, a
venture capital partnership located in Chicago,  Illinois. From 1986 to 1990, he
was  Vice   President   of  Business   Development   of  Houston   Biotechnology
Incorporated.  From 1984 to 1986,  he was  Manager of Business  Development  for
California  Biotechnology,  Inc. From 1982 to 1984,  he was Product  Manager for
Bethesda Research  Laboratories,  Inc., a supplier of genetic engineering tools.
From 1980 to 1982,  he was  Marketing  Manager and head of  Boehringer  Mannheim
GmbH's  subsidiary  in  Copenhagen,  Denmark.  Mr. Borg  received his M.B.A.  in
Marketing  from  INSEAD  in  Fontainebleau,  France  and  his  M.Sc.  degree  in
Biochemistry from the University of Copenhagen.

PHILIP R. TRACY
CHAIRMAN OF THE BOARD OF DIRECTORS

         Mr.  Tracy has been a director of the Company  since  October  1995 and
Chairman  of the Board  since May 1996.  Mr.  Tracy is  presently  of counsel to
Smith, Anderson,  Blount, Dorsett, Mitchell and Jernigan, a law firm in Raleigh,
North  Carolina.  From 1989 until its sale to Glaxo Inc. in 1995,  Mr. Tracy was
President and Chief Executive Officer of Burroughs

                                      -3-

<PAGE>

Wellcome Co. and a member of the Board of  Directors  of Burroughs  Wellcome Co.
and its parent organizations,  The Wellcome Foundation Limited and Wellcome plc.
From 1974 to 1989, Mr. Tracy held several  positions in the legal  department of
Burroughs  Wellcome  Co.,  including as Vice  President,  Secretary  and General
Counsel  from  1981 to  1989.  Mr.  Tracy  currently  serves  as a  director  of
Pharmanetics,  Inc. He is also a venture  partner in InterSouth  Associates  IV,
LLC, a venture  capital fund that  invests in  early-stage  technology  and life
sciences  companies.  He received a B.A. from the University of Nebraska and his
L.L.B. from George Washington University.


CHARLES L. DIMMLER III
DIRECTOR

         Mr.  Dimmler has been a director of the Company since 1997. Mr. Dimmler
has been an operating officer of Cross Atlantic Partners, Inc. and an investment
officer of the Cross Atlantic  Partners Funds since 1994.  From 1988 to 1994, he
was a General Partner of the former Hambro International Equity Partners. During
the period 1986-88,  Mr. Dimmler operated Metcalf Ross & Company,  a business he
formed to manage and  commercialize  intellectual  property  owned by  prominent
medical research  institutions in the United States. Mr. Dimmler's experience in
entrepreneurship and venture development originates from 1982 when he co-founded
Applied Immune Sciences, Inc., a Santa Clara,  California-based company which is
now a unit of RPR Gencell (Rhone-Poulenc Rorer). Mr. Dimmler serves on the board
of  GeneLogic,  Inc.,  as well as  several  publicly  privately  held  portfolio
companies  which  specialize  in human health care.  He also serves as a venture
advisor to Burrill & Company,  a San Francisco  based private  merchant  banking
concern.


JERRY T. JACKSON
DIRECTOR

         Mr. Jackson has been a director of the Company since August 1996.  From
1965 until his  retirement in 1995,  Mr.  Jackson was employed with Merck & Co.,
Inc.  in  various  senior  management  positions,  including  at his  retirement
Executive Vice President of Merck & Co., Inc. Mr. Jackson  currently serves as a
director on the boards of Crescendo  Pharmaceuticals  Corp.,  Cor  Therapeutics,
Inc. and Molecular Biosystems,  Inc. and as Chairman of Transcend  Therapeutics,
Inc.


ROBERT S. JANICKI, M.D.
DIRECTOR AND MEMBER OF THE PHARMACEUTICAL ADVISORY BOARD

         Dr.  Janicki has been a director of the Company since 1991 and a member
of the Pharmaceutical  Advisory Board since 1993. From 1969 until his retirement
as Senior Vice President for  Scientific & Medical  Affairs in 1992, Dr. Janicki
was employed by Abbott Laboratories. From 1968 to 1969, he was Associate Medical
Director of Union Carbide Corporation's  pharmaceutical  division, and from 1966
to  1968,  he  was  Associate   Director  of  Clinical   Research  for  the  Dow
Pharmaceutical  Division  of Dow  Chemical  Company.  Dr.  Janicki  served  as a
director of Cetus  Corporation  prior to its merger with Chiron  Corporation and
currently serves as a director of Afferon Corporation (Wayne,  Pennsylvania),  a
privately-held  pharmaceutical  company. He is presently engaged as a consultant
to several  health care  companies.  Dr.  Janicki  received his M.D. from Temple
University School of Medicine.


JAY MOORIN
DIRECTOR

         Mr. Moorin has been a director of the Company since  November 1997. Mr.
Moorin is currently a partner in ProQuest,  a venture  capital firm that focuses
its  investments in oncology.  From 1991 to 1998 he was Chairman,  President and
Chief   Executive   Officer  of  Magainin   Pharmaceuticals,   Inc.,   a  public
biopharmaceutical  company engaged in identifying and developing  compounds from
the host  defense  systems of animals.  Prior to joining  Magainin,  Mr.  Moorin
served as a Managing  Director at Bear,  Stearns & Co.,  Inc.,  responsible  for
health care investment banking,  and in other capacities from 1988 to 1991. From
1983 to 1988,  he was employed by E.R.  Squibb & Co.,  Inc.,  first as Corporate
National  Accounts  Director and subsequently as Vice President of Marketing and
Business Development at the Squibb Mark Division.

                                      -4-

<PAGE>

ROBERT A. SCHOELLHORN
DIRECTOR

         Mr.  Schoellhorn  has been a director  of the Company  since 1993.  Mr.
Schoellhorn is presently Chairman and Chief Executive Officer of Marathon Coach,
Inc.  (Eugene,  Oregon),  a privately held company owned by Mr.  Schoellhorn and
certain members of his family which manufactures luxury motor coaches. From 1973
until  his  retirement  in  1990,  Mr.  Schoellhorn  was  employed  with  Abbott
Laboratories in various senior management  positions,  including Chief Executive
Officer  since 1979 and Chairman of the Board since 1981.  For 26 years prior to
joining Abbott, Mr. Schoellhorn held various management  positions with American
Cyanamid Corporation.  Mr. Schoellhorn is presently Chairman and Chief Executive
Officer of Outdoor Resorts of America,  Inc., a developer and operator of luxury
recreational  resorts.  In addition,  Mr.  Schoellhorn  is on the board of First
Community  Bank of the Desert,  and has  previously  served on the boards of SCM
Corporation,  Pillsbury,  ITT and Shell Oil  Company.  He is a  graduate  of the
Philadelphia College of Textiles and Science, where he majored in chemistry.

         THE BOARD OF  DIRECTORS  RECOMMENDS  THAT  STOCKHOLDERS  VOTE AFOR" THE
ELECTION OF EACH OF THE ABOVE-NAMED NOMINEES.

DIRECTORS' MEETINGS AND COMPENSATION

         During  1998,  the  Board of  Directors  met 7 times  and took  certain
additional  actions by unanimous  written  consent in lieu of  meetings.  During
1998, no director of the Company  attended fewer than 75 percent of the meetings
of the Board of Directors,  except for Jacques  Rejeange,  a former director who
resigned  effective  March 31, 1999,  who  attended  none of the meetings of the
Board of Directors.

         Each nonemployee director receives $1,500 for each meeting of the Board
of Directors  or of a committee  of the Board of Directors  which is attended in
person,  provided  that  in the  event  a  committee  meeting  is  scheduled  in
conjunction  with a Board meeting,  only one payment will be received.  Payments
for  participation  in a telephonic  meeting of the Board of Directors and Board
committees are $750. All directors receive  reimbursement of reasonable expenses
incurred in attending  meetings.  Officers are elected  annually by the Board of
Directors and serve at the discretion of the Board.

         In  addition,  pursuant  to the  Company's  Amended and  Restated  1995
Nonemployee  Directors'  Stock Option Plan, each director who is not an employee
of or  consultant  to the Company  receives an initial  stock option to purchase
25,000  shares of the  Company's  Common Stock upon election to the Board and an
annual stock option to purchase 5,000 shares of the Company's Common Stock, with
vesting  contingent on providing  services over the following twelve months. The
Chairman of the Board receives an additional  annual stock option under the 1995
Nonemployee  Directors'  Stock Option Plan to purchase  10,000  shares of Common
Stock.

BOARD COMMITTEES

         The Company's Board of Directors has an Audit  Committee,  Compensation
Committee,  Option  Committee and Nominating  Committee.  The Audit  Committee's
functions   include   making   recommendations   concerning  the  engagement  of
independent   public   accountants,   reviewing  with  the  independent   public
accountants  the  plan  and  results  of  the  auditing  engagement,   approving
professional  services  provided  by  the  independent  public  accountants  and
reviewing  the  adequacy of the  Company's  internal  accounting  controls.  The
Compensation Committee makes recommendations concerning compensation,  including
incentive  arrangements,  for  the  Company's  officers.  The  Option  Committee
administers  the  Company's  Amended  and  Restated  1994 Stock  Option Plan and
approves  all  stock  options   awarded  under  it.  The  Nominating   Committee
establishes procedures for the evaluation and selection of nominees to the Board
of Directors,  and is also responsible for the smooth and orderly  transition in
the Company's management, in the event such a need arises.

         During 1998,  the  Nominating  Committee  met one time,  and the Audit,
Option and Compensation Committees did not meet. During 1998, no director of the
Company attended fewer than 75 percent of the meetings of committees on which he
served.

         THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE AFOR" PROPOSAL
NUMBER 1, AND PROXIES  EXECUTED  AND RETURNED  WILL BE SO VOTED UNLESS  CONTRARY
INSTRUCTIONS ARE INDICATED THEREON.

                                      -5-

<PAGE>

                               PROPOSAL NUMBER 2:

                     APPROVAL OF PRIVATE PLACEMENT OF SHARES

         As indicated in the  Company's  Annual Report on Form 10-K for the year
ended December 31, 1998, the Company is in need of additional  financing to fund
the Company's  operations.  As of March 31, 1999,  the Company had $1,013,000 of
working  capital  and  $1,389,000  of cash and  cash  equivalents.  The  Company
currently  estimates  that  cash on  hand  together  with  cash  generated  from
operations  will be sufficient to satisfy the Company's cash  requirements  into
but not beyond the third quarter of 1999.  The Board of Directors of the Company
has  considered  various  means  of  procuring   additional  financing  and  has
determined  that a private  offering of the Company's  securities  (the "Private
Placement")  would be in the best interests of the Company.  The net proceeds of
the Private  Placement  will be used to fund  continuing  operations,  including
research and development and general working capital purposes.

         The  Company  has  had  preliminary  discussions  with  certain  of its
existing  stockholders  regarding  the  Private  Placement,  which is  currently
anticipated to consist of up to 2,500,000  shares of the Company's  Common Stock
and  may  include  warrants  (the  "Warrants")  exercisable  for  shares  of the
Company's  Common  Stock.  Based upon these  initial  discussions,  the  Company
believes  that there is  significant  interest  in the Private  Placement  among
existing  institutional  investors  as  well as  potential  new  investors.  The
purchase price for the shares of Common Stock sold in the Private Placement will
be determined through negotiations between the Company and the investors,  based
upon the demand for the  Company's  Common Stock and its closing price or prices
on the Nasdaq  Small Cap Market  prior to the closing of the Private  Placement.
Due to the fact  that  the  shares  sold in the  Private  Placement  will not be
immediately freely tradeable by the purchasers until such time as a registration
statement  registering  such  shares is filed and  becomes  effective  under the
Securities  Act of 1933, as amended,  it is  anticipated  that the shares may be
sold at a discount  from the  closing  price or prices of the  Company's  Common
Stock on the Nasdaq Small Cap Market prior to closing. The actual amount of such
discount is not known at this time,  but is not expected to exceed 20%, which is
not uncommon for offerings of restricted  shares by public  companies in similar
transactions.

         Pursuant to Rule  4460(i)(1)(D)  ("Rule  4460(i)(1)(D)")  of the Nasdaq
Stock Market,  Inc.  ("Nasdaq"),  the Company is required to obtain  stockholder
approval in connection with any transaction,  other than a public offering, that
involves the issuance by the Company of Common Stock (or securities  convertible
into or exercisable or exchangeable for Common Stock) that equals 20% or more of
the  Common  Stock  of the  Company  outstanding  before  the  issuance  of such
securities  at a price below market value (the "20%  Limitation").  On April 23,
1999,  the closing sale price of the  Company's  Common Stock as reported on the
Nasdaq Small Cap Market was $1.75 per share.  The Company  currently  expects it
would  require $8.0 million to fund  operations  through 2000. As of the date of
this proxy statement, there are 6,922,518 shares of Common Stock outstanding and
366,667  shares of Common Stock  issuable  upon the  conversion  of  outstanding
shares of Series A Preferred  Stock and Series B Preferred  Stock.  Thus, if the
Company closes the Private  Placement when  subscriptions  for 2,500,000  shares
have been received, which is the maximum number of shares offered in the Private
Placement,  the 20% Limitation would be exceeded,  based on the market value and
the number of shares of the Company's Common Stock outstanding as of the date of
this Proxy Statement.  If the  stockholders  approve this Proposal Number 2, the
Board of Directors of the Company will be authorized to determine (i) the number
of shares of Common Stock that will be issued in the Private Placement,  even if
in excess of 20% of the Common Stock outstanding (ii) the purchase price of such
shares of Common Stock and (iii) whether  Warrants will be issued in the Private
Placement and, if so, the terms and conditions of the Warrants. The stockholders
will  be  requested  to  approve  this   proposal  by  adopting  the   following
resolutions:


         RESOLVED,  that this  Corporation be authorized to consummate a private
         placement of its securities (the "Private Placement"),  the proceeds of
         which would be utilized for research and  development,  working capital
         and general corporate  purposes  (including the expenses of the Private
         Placement), and that in connection therewith this Corporation is hereby
         authorized to issue shares of its Common  Stock,  $.0001 par value (the
         "Common  Stock"),  and securities  exercisable  for Common Stock,  that
         together equal 20% or more of the Common Stock outstanding prior to the
         issuance thereof; and it is further

         RESOLVED,  that the Board of Directors of this  Corporation  (and/or an
         appropriate  committee  thereof) is hereby  authorized to determine the
         terms  and  conditions  of the  Private  Placement,  including  without
         limitation,  (i) the  number of shares  of  Common  Stock  that will be
         issued in the  Private  Placement  (which  may exceed 20% of the Common
         Stock  outstanding and securities  exercisable for Common Stock),  (ii)
         the  purchase  price of such shares of Common  Stock and (iii)  whether
         Warrants will be issued in the Private Placement,  and if so, the terms
         and conditions of the Warrants issued in the Private Placement.

                                      -6-

<PAGE>

         The Board of Directors  of the Company has decided to seek  stockholder
approval of the Private  Placement  in order to avoid a possible  conflict  with
Rule 4460(i)(1)(D),  which conflict could result in the removal of the Company's
Common Stock from  inclusion  on the Nasdaq  National  Market.  In the event the
Company fails to obtain approval by the stockholders for the Private  Placement,
the Company  will be  required  to seek  alternative  means of  financing.  Such
financing  would likely be in the form of short term bridge loans.  There can be
no  assurance  that  such  financing  can  be  obtained  on a  timely  basis  on
commercially reasonable terms, or at all. Further, even if such short term loans
were obtained,  the Company would be required  within a short time thereafter to
seek  additional  financing  to repay such loans and to finance its  operations.
There can be no assurance that such  additional  financing could be obtained and
that the Company  would not again be required to seek  stockholder  approval for
such financing.

         The Company's Common Stock is quoted on the Nasdaq Small Cap Market. In
order to maintain  quotation of the Common Stock on the Nasdaq Small Cap Market,
the Company must  maintain  certain  asset,  capitalization  or income tests and
stock price tests.  Among other  requirements,  the Company must maintain either
(i) net tangible assets in excess of $2.0 million,  (ii) a market capitalization
of at least $35  million,  or (iii) net income of $500,000 in the most  recently
completed fiscal year or in two of the last three completed fiscal years, and in
any event, a bid price of at least $1.00 per share in the most recent thirty day
period.  While the  Company  currently  satisfies  the  Nasdaq  Small Cap Market
Listing and Maintenance Standards, if the Company is unable to obtain additional
financing  either  through the Private  Placement or otherwise,  the Company may
fail to meet the  maintenance  criteria in the  future,  which may result in the
Common  Stock no longer  being  eligible  for  quotation on the Nasdaq Small Cap
Market.  If the Common Stock is delisted from  quotation on the Nasdaq Small Cap
Market, then there would be material adverse  consequences for the Company,  its
results of operations and its financial condition.  These consequences  include,
but are not limited to:

         o        limited  availability  of market  quotations for the Company's
                  Common Stock;
         o        limited news and analyst coverage of the Company;
         o        adverse  affect on the trading  market for and market price of
                  the Company's Common Stock; and
         o        adverse  affect on the Company's  ability to issue  additional
                  securities or secure additional financing in the future.

         If the  Company's  Common Stock is no longer  eligible for quotation on
Nasdaq,  then trading, if any, of the Common Stock would thereafter be conducted
in the over-the-counter market. As a result of Nasdaq delisting, it would likely
be  more  difficult  for  stockholders  to  dispose  of  or to  obtain  accurate
quotations  as to the  market  value of their  Common  Stock.  Furthermore,  the
regulations of the Commission  promulgated under the Securities  Exchange Act of
1934, as amended (the "Exchange Act"), require additional disclosure relating to
the market for penny stocks.  Commission  regulations  generally  define a penny
stock to be an equity  security  that has a market  price of less than $5.00 per
share, subject to certain exceptions. A disclosure schedule explaining the penny
stock market and the risks  associated  with such  securities  is required to be
delivered to a purchaser and various sales practice  requirements are imposed on
broker-dealers  who sell  penny  stocks to  persons  other  than to  established
customers and  accredited  investors  (generally  institutional  investors).  In
addition, the broker-dealer must provide the customer with current bid and offer
quotations for the penny stock,  the compensation of the  broker-dealer  and its
salesperson in the transaction and monthly account statements showing the market
value of each  penny  stock held in the  customer's  account.  If the  Company's
securities were to become subject to the regulations applicable to penny stocks,
the market liquidity for the Company's securities could be severely affected. In
such an event,  the  regulations  on penny  stocks  could  limit the  ability of
broker-dealers  to sell  the  Company's  securities  and  thus  the  ability  of
purchasers of the Company's securities to sell their securities in the secondary
market.

         The Company  believes  that  notwithstanding  the  consummation  of the
Private  Placement,  it will be required  to seek  additional  financing  in the
future to fund its  operations  and to continue to develop its products.  If the
minimum amount proposed to be offered is sold, the Company  anticipates  that it
cash requirements  should be satisfied through the first quarter of 2000. Should
additional  shares be sold,  such cash  requirement  should be  satisfied  for a
longer period.

CAPITALIZATION

         The  following  table  sets  forth  the  short-term  debt and the total
capitalization  of the Company (i) as of March 31, 1999,  (ii) pro forma to give
effect to the sale of the minimum and maximum  number of shares of Common  Stock
in the

                                     - 7 -

<PAGE>

Private  Placement  at an  assumed  offering  price of $1.60  per  share and the
application of the estimated net proceeds  therefrom,  after deducting  offering
expenses estimated at $50,000.  The table should be read in conjunction with the
financial  statements,  including the notes  thereto,  attached to the Company's
report on Form 10-K for 1998 enclosed with this Proxy Statement.

<TABLE>
<CAPTION>

                                             MARCH 31, 1999
                                             --------------
                                                                                     PRO FORMA(1)
                                                                                     ------------
                                                                          Minimum Offering    Maximum Offering
                                                              ACTUAL     (1,000,000 SHARES)  (2,500,000 SHARES)
                                                           ------------  ------------------  ------------------

<S>                                                        <C>           <C>                  <C>            
Current Liabilities: ...................................   $    526,450  $         526,450    $       526,450

Long-term debt, including capital lease
    obligations ........................................             --                 --                 --

Stockholders' equity:
  Preferred Stock, $.001 par value, 300,000 shares
    authorized, issued and outstanding .................            300                300                300

  Series B Preferred Stock, $.001 par value, 200,000
shares authorized and 66,667 issued and outstanding ....             67                 67                 67

  Common Stock, $.0001 par value; 25,000,000 shares
    authorized; 6,914,728 shares issued and outstanding,
    actual; 7,914,728 shares issued and outstanding, pro
    forma, assuming the minimum number of shares;
    9,414,728 shares issued and outstanding, pro forma
    assuming the maximum number of shares ..............            691                791                941

Additional paid-in capital .............................     21,438,234         22,988,194         25,388,044

Accumulated deficit ....................................    (20,130,773)       (20,130,733)       (20,130,773)

Total stockholders' equity .............................      1,308,579          2,858,574          5,188,579

Total capitalization ...................................   $  1,835,029  $       3,385,029    $     5,715,029

</TABLE>

- ------------
(1)      The pro forma balance  sheet data as of March 31, 1999,  give effect to
         the  issuance  of  1,000,000  and  2,500,000  shares of  Common  Stock,
         respectively,  which is the  minimum  and  maximum  number of shares of
         Common Stock that may be issued pursuant to the Private Placement,  and
         the receipt of the net proceeds therefrom.

INTEREST OF CERTAIN PERSONS IN MATTERS TO BE ACTED UPON

         Certain directors and executive  officers of the Company have expressed
a preliminary interest in purchasing  securities in the Private Placement.  Such
directors and executive officers will not make a decision regarding investing in
the  Private  Placement  until  the  terms of the  Private  Placement  have been
finalized.  Should such directors and executive officers choose to invest in the
Private Placement, their investment would be on the same terms and conditions as
are available to other investors in the Private Placement.

                                     - 8 -

<PAGE>

DILUTIVE EFFECT OF PRIVATE PLACEMENT ON PREFERRED STOCK

         Holders of the  Company's  Series A  Redeemable  Convertible  Preferred
Stock and  Series B  Redeemable  Convertible  Preferred  Stock  (the  "Preferred
Stock") have the right to convert their shares of Preferred Stock into shares of
the  Company's  Common Stock based upon a formula as set forth in the  Company's
Certificate of the Powers, Designations,  Preferences and Rights of the Series A
Redeemable   Convertible   Preferred   Stock  and  the  Certificate  of  Powers,
Designations,  Preferences  and  Rights of the Series B  Redeemable  Convertible
Preferred  Stock  (the  "Certificates  of  Designations")  filed  as part of the
Company's Certificate of Incorporation.  Prior to the completion of the proposed
Private  Placement,  the 366,667  shares of Preferred  Stock  outstanding  would
convert into an aggregate of 366,667  shares of Common Stock.  Assuming the sale
of all 2,500,000  shares of Common  Stock,  the maximum  contemplated  under the
Private  Placement at a price of $1.60 per share, the aggregate number of shares
of Common Stock  issuable upon  conversion of Preferred  Stock would increase by
13,756 shares to an aggregate of 380,423  shares.  In the event that the minimum
number of shares contemplated under the Private Placement are sold at a price of
$1.60 per  share,  the number of shares of Common  Stock that would be  issuable
upon  conversion  of the  Preferred  Stock would  increase by 6,047 shares to an
aggregate of 372,714 shares.

         The  adoption of the proposal to approve the issuance by the Company in
a private  placement  of a number of shares of Common Stock in excess of the 20%
Limitation,  requires  the  approval  by  affirmative  vote of not  less  than a
majority  of the votes  present  in person  or by proxy at the  Annual  Meeting,
provided  that a quorum is present at the Annual  Meeting.  An  abstention  or a
broker non-vote will have no effect on the vote on the proposal  provided that a
quorum is present at the Annual Meeting. Unless otherwise specified, all proxies
received will be voted in favor of Proposal Number 2.

         THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSAL
NUMBER 2, WHICH IS TO ISSUE SHARES OF COMMON STOCK AND WARRANTS  EXERCISABLE FOR
COMMON STOCK IN A PRIVATE  PLACEMENT IN EXCESS OF 20% OF THE OUTSTANDING  NUMBER
OF SHARES OF COMMON  STOCK,  AND PROXIES  EXECUTED AND RETURNED WILL BE SO VOTED
UNLESS CONTRARY INSTRUCTIONS ARE INDICATED THEREON.

                               PROPOSAL NUMBER 3:

           RATIFICATION AND APPROVAL OF INDEPENDENT PUBLIC ACCOUNTANTS

         The Board of Directors  has appointed the firm of Deloitte & Touche LLP
as the Company's  independent  public  accountants to make an examination of the
accounts of the Company for the fiscal year ending December 31, 1999, subject to
ratification by the Company's stockholders. Representatives of Deloitte & Touche
LLP will be present at the Annual Meeting and will have an opportunity to make a
statement,  if they desire to do so. They will also be  available  to respond to
appropriate questions from stockholders attending the Annual Meeting.

         Stockholder  ratification  of the selection of Deloitte & Touche LLP as
the Company's  independent  public  accountants is not required by the Company's
Bylaws or otherwise.  However, the Board is submitting the selection of Deloitte
& Touche LLP to the  stockholders for ratification as a matter of good corporate
practice. If the stockholders fail to ratify the selection,  the Audit Committee
and the Board will  reconsider  whether  or not to retain the firm.  Even if the
selection is ratified, the Audit Committee and the Board in their discretion may
direct the appointment of different  independent  public accountants at any time
during  the  year if they  determine  that  such a  change  would be in the best
interests of the Company and its stockholders.

         THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSAL
NUMBER 3, AND PROXIES  EXECUTED  AND RETURNED  WILL BE SO VOTED UNLESS  CONTRARY
INSTRUCTIONS ARE INDICATED THEREON.

                                     - 9 -

<PAGE>

                             EXECUTIVE COMPENSATION

EXECUTIVE OFFICERS

         Set  forth  below  is  certain  information  concerning  the  executive
officers of the Company,  including  the business  experience of each during the
past five years.

NAME                          AGE    POSITION WITH THE COMPANY
- ----                          ---    -------------------------

Stefan Borg................... 45    President and Chief Executive Officer
Paul M. Herron ............... 50    Vice President and Chief Financial Officer
Cecilia Bryant ............... 52    Vice President-Legal Affairs, Secretary 
                                       and General Counsel
Ronald W. Sanda............... 56    Vice President-Manufacturing and Operations
Michael T. Cullen, M.D........ 53    Vice President and Medical Director

         Information  regarding the business experience of Mr. Borg is set forth
above under the heading "Nominees for Election as Directors."

PAUL M. HERRON
VICE PRESIDENT AND CHIEF FINANCIAL OFFICER

         Mr. Herron has been Vice President and Chief  Financial  Officer of the
Company since  September 1997. From 1994 to 1997, he was Director of Finance and
Investor  Relations for  Immunomedics,  Inc.  From 1990 to 1994,  Mr. Herron was
employed by The Dupont Merck  Pharmaceutical  Co. as Finance  Manager for two of
the company's operating businesses,  radiopharmaceuticals  from 1990 to 1991 and
multi-source products from 1991 to 1994. Previously, he served for 14 years with
the  Finance  Department  of E. I.  DuPont de  Nemours  & Co.  in a  variety  of
corporate  finance  assignments,   including  accounting,  taxes,  and  employee
benefits.  Mr.  Herron  received an M.B.A.  from Duke  University  and a B.A. in
economics from Trinity College in Hartford, Connecticut.

CECILIA BRYANT
VICE PRESIDENT-LEGAL AFFAIRS, SECRETARY AND GENERAL COUNSEL

         Ms. Bryant has been Secretary, Vice President-Legal Affairs,  Secretary
and General  Counsel of the Company since  September 1996 on a part-time  basis.
Ms. Bryant was an attorney with the Securities and Exchange Commission from 1973
to 1975 and was in private  practice  prior to  serving  as  Special  Counsel of
Voyager Insurance Companies from 1978 to 1986,  returning  thereafter to private
practice.  Ms. Bryant served from 1982 to 1989 on the Florida  University System
Board of Regents and in 1989 was its Vice Chairman.  Ms. Bryant received her law
degree from the University of Florida and is a Certified Life Underwriter  (CLU)
and a Chartered  Financial  Consultant (ChFC). She is an Associate  Professor at
Florida  Coastal School of Law and a director of SunTrust Bank of North Florida,
N.A.

RONALD W. SANDA
VICE PRESIDENT-MANUFACTURING AND OPERATIONS

         Mr. Sanda has been Vice  President-Manufacturing  and Operations of the
Company since July 1994.  Mr. Sanda was Director,  Quality  Assurance of Houston
Biotechnology  Incorporated  from 1988 to 1994. From 1986 to 1988, Mr. Sanda was
Director, Quality Assurance of Biospecific Technologies, Inc. From 1961 to 1986,
Mr.  Sanda was  employed  by Ben Venue  Laboratories,  Inc.  in various  quality
assurance and GMP compliance  functions.  Mr. Sanda has a B.S. in Chemistry from
Kent State University.

                                     - 10 -

<PAGE>

MICHAEL T. CULLEN, M.D.
VICE PRESIDENT AND MEDICAL DIRECTOR

         Dr. Cullen has been Vice President and Medical  Director of the Company
since September 1998. Prior to joining SunPharm, he was Vice President, Clinical
Consulting  for IBAH Clinical  Consulting  Services from 1997 to 1998,  and from
1995 to 1997  Vice  President  and  Medical  Director  for that  Company's  U.S.
Business Development from 1994 to 1995. Dr. Cullen was CEO and co-founder of IDD
Medical,  Inc., and assistant and associate  director,  Clinical Research for 3M
Pharmaceuticals from 1988 to 1994.  Previously,  he was a consultant in internal
medicine in Owatonna,  Minnesota from 1977 to 1988, and served with the National
Center for Disease  Control from 1972 to 1974. Dr. Cullen is board  certified in
internal  medicine and earned his M.D. at the  University  of Minnesota  Medical
School in 1971. He also received an M.B.A.  from the University of St. Thomas in
St. Paul, Minnesota in 1991.

COMPENSATION OF EXECUTIVE OFFICERS

         SUMMARY COMPENSATION TABLE

         The following  table provides  certain summary  information  concerning
compensation  paid or  accrued  during  the last  three  years to the  Company's
President  and  Chief  Executive  Officer  and to  each of the  other  executive
officers of the Company, determined as of the end of the last fiscal year, whose
annual compensation exceeded $100,000 (the "Named Executive Officers"):

<TABLE>
<CAPTION>

                                                                        LONG-TERM
                                                                       COMPENSATION
                                                                          AWARDS
                                                                     ----------------
   NAME AND PRINCIPAL POSITION     YEAR    ANNUAL COMPENSATION          SECURITIES 
   ---------------------------     ----   ----------------------     UNDERLYING OPTIONS   ALL OTHER
                                           SALARY        BONUS       (NUMBER OF SHARES)  COMPENSATION
                                          --------      --------     ------------------  ------------
<S>                                <C>    <C>           <C>                <C>            <C>    
Stefan Borg ....................   1998   $200,000      $     --                --             --
    President and Chief ........   1997    190,833        15,000            25,000             --
    Executive Officer ..........   1996    163,125        18,750                --             --

Paul M. Herron .................   1998   $125,000      $     --                --       $ 11,145(2)
    Vice President and Chief ...   1997     36,458(1)         --            50,000             --
    Financial Officer ..........   1996         --            --                --             --

Ronald W. Sanda ................   1998   $112,500      $     --                --             --
    Vice President-Manufacturing   1997    103,444         4,300             7,500             --
    and Operations .............   1996    102,812         7,500                --             --

</TABLE>

- ----------
(1)      Mr. Herron commenced employment in September 1997.
(2)      Relocation expenses.

                                     - 11 -

<PAGE>

         OPTION GRANTS IN 1998

         No stock options were granted  during the year ended December 31, 1998,
to the Company's  Chief  Executive  Officer or to the other  executive  officers
included in the Summary Compensation Table.

         OPTION VALUES

         The  following  table  provides  information  concerning  the  value of
unexercised  options held as of December 31, 1998 the Company's  Chief Executive
Officer and its other executive officers named in the Summary Compensation Table
(no options  were  exercised  during such  year).  The fair market  value of the
shares of Common  Stock  underlying  such  options was  determined  by using the
closing bid price of the Company's Common Stock, which was $1.00 per share as of
December 31, 1998.

<TABLE>
<CAPTION>

                                 NUMBER OF SECURITIES
                                UNDERLYING UNEXERCISED              VALUE OF UNEXERCISED
             NAME           OPTIONS HELD AT DECEMBER 31, 1998   OPTIONS HELD AT DECEMBER 31, 1998
             ----           ---------------------------------   ---------------------------------
                            EXERCISABLE         UNEXERCISABLE   EXERCISABLE        UNEXERCISABLE
                            -----------         -------------   -----------        -------------
<S>                           <C>                  <C>           <C>                 <C>      
Stefan Borg.................  53,615               18,125        $  53,615           $  18,125

Paul M. Herron..............  10,417               39,583           10,417              39,583

Ronald W. Sanda.............  50,406                6,044           50,406               6,044

</TABLE>

EMPLOYMENT AGREEMENTS

         Messrs.  Borg,  Herron,  Sanda and Dr.  Cullen have each  entered  into
employment  agreements  with the  Company  which are  renewed  on a year to year
basis;  provided  however,  that  either  party  may  thereafter  terminate  the
agreement on sixty days notice subject to the employee's right to receive either
full salary  continuation  for up to six months or one-half salary  continuation
for twelve  months in the event of  termination  without  cause,  except for Mr.
Borg,  who is entitled to one year salary as severance  pay. The President has a
policy of  reviewing  the salary of  employees  on an annual  basis and may make
salary and bonus  recommendations  to the  Compensation  Committee.  Mr. Borg's,
Herron's and Sanda's and Dr.  Cullen's  current  annual  salaries are  $200,000,
$125,000,  $112,500  and  $175,000,  respectively.  Bonuses  are  payable at the
discretion of the  Compensation  Committee,  depending on the performance of the
individual  and the financial  position of the Company.  No bonuses were paid in
1998.

         The Company has engaged Dr. Bergeron as its Chief Scientific Consultant
in the areas of polyamine  analogues and metal  chelators on an exclusive  basis
through December 2000, at a current rate of $96,000 per year. Such agreement may
be terminated by the Company in the event the Sponsored  Research Agreement with
the University of Florida Research Foundation terminates.

                              CERTAIN TRANSACTIONS

         On March 31, 1997, the Company loaned Mr. Borg $87,491 at 8% per annum,
due  March  31,  1998;  this  loan has been  extended  by the Board at a current
interest rate of 8% per annum. A total of $114,816 was  outstanding on this loan
on March 31, 1999.

         The Company  entered into License  Agreements  with the  University  of
Florida Research Foundation, Inc. in December 1991 and October 1995. The Company
has issued the  Foundation a total of 342,760  shares of Common Stock in partial
consideration  for the rights  granted  under the  License  Agreements,  and has
ongoing royalty obligations under the License Agreements. The Company is a party
to a Sponsored  Research  Agreement with the Foundation  under which the Company
has agreed to fund research at the  University of Florida  through the year 2000
at a cost of approximately $875,000 per year.

                                     - 12 -

<PAGE>

         On March 31,  1997,  the Company  sold an  aggregate  of 714,286  units
("Units") each consisting of one share of Common Stock and a warrant to purchase
one share of Common Stock,  to Cross  Atlantic  Partners K/S and Cross  Atlantic
Partners II K/S (together,  "Cross  Atlantic") at a price of $3.50 per Unit. Mr.
Dimmler is an affiliate of Cross Atlantic. In addition,  Mr. Dimmler and members
of his family purchased 4,000 Units at the same price.

                                     - 13 -

<PAGE>

         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

         The  following  table  presents  certain   information   regarding  the
beneficial  ownership of the Company's  Common Stock as of March 31, 1999 by (I)
each  person  who is known by the  Company  to own  beneficially  more than five
percent of the  outstanding  shares of Common  Stock,  (ii) each director of the
Company, (iii) the Company's chief executive officer and each of the other Named
Executive  Officers and (iv) all directors  and  executive  officers as a group.
Except as  described  below,  each of the  persons  listed in the table has sole
voting and investment power with respect to the shares listed.

<TABLE>
<CAPTION>

                                          COMMON STOCK            SERIES A PREFERRED STOCK SERIES B PREFERRED STOCK
                                          ------------            ------------------------ ------------------------
                                                      PERCENTAGE              PERCENTAGE               PERCENTAGE
                 NAME                      NUMBER OF BENEFICIALLY  NUMBER OF BENEFICIALLY  NUMBER OF  BENEFICIALLY
                 ----                      SHARES(1)    OWNED      SHARES(1)    OWNED      SHARES(1)      OWNED
                                           --------- ------------  --------- ------------  ---------  ------------

<S>                          <C>           <C>          <C>        <C>          <C>          <C>           <C>
Cross Atlantic Partners Funds(2).....      1,428,572    18.7%           --        --            --           --
New York Life Insurance Company(3)...      1,142,858    15.3%           --        --            --
Pensionskassen for
Vaerkstedfunktionaerer i Jernet(4)...        617,261     8.8%      123,375      41.1%           --           --
Stefan Borg(5).......................        521,098     7.5%           --        --            --           --
Apoteksassistenternes Pensionskasse(6)       474,404     6.7%      123,375      41.1%           --           --
InterSouth Partners III, L.P.(7).....        467,559     6.6%       25,000       8.3%                        --
University of Florida Research
Foundation, Inc.(8)..................        342,760     5.0%           --        --            --           --
Uni-invest(9)........................        250,000     3.6%           --        --        66,667        100.0%
Philip R. Tracy(10)..................         70,000     1.0%           --        --            --           --
Charles L. Dimmler, III(11)..........      1,476,275    21.2%        1,750         *            --           --
Jerry T. Jackson(12).................         35,000      *             --        --            --           --
Robert S. Janicki(13)................        188,397     2.7%           --        --            --           --
Jay Moorin(14).......................         30,000      *             --        --            --           --
Robert A. Schoellhorn(15)............        154,350     2.2%           --        --            --           --
Paul M. Herron(16)...................         18,383      *             --        --            --           --
Ronald W. Sanda (17).................         50,664      *             --        --            --           --
All executive officers and directors
as a group (11) persons (5)(10)-(17).      2,612,630    31.9%        6,108       2.0%           --           --

</TABLE>

- ----------
*        Less than one percent.

(1)      Beneficial  ownership is determined in accordance with the rules of the
         Securities and Exchange  Commission.  In computing the number of shares
         of  Common  Stock  beneficially  owned by a person  and the  percentage
         ownership of that person,  shares of Common Stock subject to options or
         warrants  held  by  that  person  that  are  currently  exercisable  or
         exercisable  within 60 days of March 31, 1999, are deemed  outstanding,
         as well as any  shares of Series A or Series B  Redeemable  Convertible
         Preferred  Stock held by that  person.  Such shares,  however,  are not
         deemed   outstanding  for  the  purpose  of  computing  the  percentage
         ownership of each other person. Except as indicated in the footnotes to
         this table and pursuant to applicable  community  property  laws,  each
         stockholder  named in the table has sole  voting and  investment  power
         with respect to the shares set forth opposite such stockholder's name.

(2)      The business address of the Cross Atlantic  Partners Funds is c/o Cross
         Atlantic Partners,  Inc., 650 Madison Avenue,  21st Floor, New York, NY
         10022. Includes warrants to purchase 714,286 shares of Common Stock.

(3)      The  business  address  of New York Life  Insurance  Co. is 51  Madison
         Avenue,  New York,  NY 10010.  Includes  warrants to  purchase  571,429
         shares of Common Stock.

(4)      The business address of  Pensionskassen  for  Vaerkstedfunktionaerer  i
         Jernet is 12 Sankt Annae Plads-DK 1250, Copenhagen K, Denmark. Includes
         123,375 shares of Series A Redeemable Convertible Preferred Stock.

                                     - 14 -

<PAGE>

(5)      Mr. Borg's business address is The Veranda, Suite 301, 814 Highway A1A,
         Ponte Vedra Beach, FL 32082. Includes options to purchase 55,698 shares
         of Common Stock.

(6)      The business address of  Apoteksassistenternes  Pensionskasse is Hojbro
         Plads 6-DK 1200,  Copenhagen K,  Denmark.  Includes  123,375  shares of
         Series A Redeemable Convertible Preferred Stock.

(7)      The business  address of  InterSouth  Partners  III, L.P. is One Copley
         Parkway,  Suite 102,  Morrisville,  NC 27560.  Includes (i) warrants to
         purchase  171,429  shares of Common  Stock  and (ii)  25,000  shares of
         Series A Redeemable Convertible Preferred Stock.

(8)      The business address of the University of Florida Research  Foundation,
         Inc. is 223 Grinter Hall, Gainesville,  FL 32611. Dr. M. Jack O'Hanian,
         President of the  Foundation,  has  investment  and voting control over
         such shares.  (9) The business  address of Uni-invest is Nyropsgade 17,
         DK 1602,  Copenhagen,  Denmark.  Includes  66,667  shares  of  Series B
         Redeemable Convertible Preferred Stock.

(10)     Mr.  Tracy's  business  address is 2500  First  Union  Capital  Center,
         Raleigh, NC 27602. Includes options to purchase 70,000 shares of Common
         Stock.

(11)     Mr. Dimmler's  business address is 650 Madison Avenue,  21st Floor, New
         York, NY 10022.  Includes (i) 3,592 shares of Common Stock, warrants to
         purchase  790  shares  of  Common  Stock,  and 700  shares  of Series A
         Convertible  Preferred  Stock  held  by  Mr.Dimmler's  children,   (ii)
         1,428,572 shares  beneficially  owned by Cross Atlantic  Partners Funds
         (including  warrants to purchase 714,286 shares),  of which Mr. Dimmler
         is an  affiliate,  (iii)  options to purchase  35,000  shares of Common
         Stock,  and (iv) 5,387  shares of Common  Stock,  warrants  to purchase
         1,184 shares of Common Stock,  and 1,050 shares of Series A Convertible
         Preferred Stock held jointly by Mr. Dimmler and his wife.

(12)     Mr. Jackson's business address is 7212 N. Secret Canyon Drive,  Tucson,
         AZ 85718. Includes options to purchase 35,000 shares of Common Stock.

(13)     Dr. Janicki's  business address is The Veranda,  Suite 301, 814 Highway
         A1A, Ponte Vedra Beach, FL 32082.  Includes  options to purchase 66,547
         shares of Common Stock and warrants to purchase  1,000 shares of Common
         Stock.

(14)     Mr.  Moorin's  business  address  is  One  Palmer  Square,  Suite  425,
         Princeton,  NJ 08542.  Includes  options to purchase  30,000  shares of
         Common Stock.

(15)     Mr.  Schoellhorn's  business  address is 91333 Coburg  Industrial  Way,
         Coburg, OR 97408.  Includes options to purchase 58,950 shares of Common
         Stock and  warrants  to purchase  79,400  shares of Common  Stock.  All
         shares and warrants are held by The Robert A.  Schoellhorn  Trust dated
         June 26, 1989, of which Mr. Schoellhorn serves as Trustee.

(16)     Mr. Herron's  business  address is The Veranda,  Suite 301, 814 Highway
         A1A, Ponte Vedra Beach, FL 32082.  Includes  options to purchase 17,083
         shares of Common Stock.

(17)     Mr.  Sanda's  business  address is The Veranda,  Suite 301, 814 Highway
         A1A, Ponte Vedra Beach, FL 32082.  Includes  options to purchase 50,664
         shares of Common Stock.


                          COMPLIANCE WITH SECTION 16(A)

         Section  16(a) of the  Securities  Exchange  Act of 1934,  as  amended,
requires the Company's directors and officers, and persons who own more than 10%
of the Common Stock, to file initial reports of ownership and reports of changes
in  ownership  (Forms  3, 4, and 5) of  Common  Stock  with the  Securities  and
Exchange Commission (the "SEC") and The Nasdaq Stock Market. Officers, directors
and greater than 10%  stockholders are required by SEC regulation to furnish the
Company with copies of all such forms that they file.

                                     - 15 -

<PAGE>

         The Company  believes  that during the fiscal year ended  December  31,
1998,  all  Section  16(a)  filing  requirements  applicable  to  its  officers,
directors and 10% stockholders were complied with in a timely manner, except for
reports on Form 5 for all officers and directors which were filed in April 1999.

                            PROPOSAL OF STOCKHOLDERS

         Any  proposal of a  stockholder  intended to be  presented  at the next
annual meeting must be received at the Company's  principal executive offices no
later than December 31, 1999, if the proposal is to be considered  for inclusion
in the Company's Proxy Statement relating to such meeting.


                                     - 16 -

<PAGE>

                              FINANCIAL INFORMATION

         A COPY OF THE  COMPANY'S  ANNUAL  REPORT ON FORM 10-KSB,  INCLUDING ANY
FINANCIAL STATEMENTS AND SCHEDULES AND EXHIBITS THERETO, MAY BE OBTAINED WITHOUT
CHARGE BY WRITTEN REQUEST TO STEFAN BORG, PRESIDENT AND CHIEF EXECUTIVE OFFICER,
SUNPHARM  CORPORATION,  THE VERANDA,  SUITE 301,  814 HIGHWAY  A1A,  PONTE VEDRA
BEACH, FLORIDA 32082.

                                        By Order of the Board of Directors


                                        Stefan Borg
                                        PRESIDENT AND CHIEF EXECUTIVE OFFICER


May 6, 1999
Jacksonville, Florida

                                     - 17 -



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