INSURED MUNICIPALS INC TR & INV QUAL TAX EX TR MULTI SER 169
497J, 1999-05-27
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                                  May 27, 1999

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

Attn:  Filing Desk - Stop 1-4

     Re:  Insured  Municipals  Income Trust and Investors'  Quality  Tax-
          Exempt Trust, Multi-Series 169
          File No. 33-46312   CIK #884923

Ladies/Gentlemen:

     In accordance with the provisions of Rule 497(j) of Regulation C under the
Securities Act of 1933 (the "Securities Act") this letter serves to certify that
the most recent amendment to the Post-Effective of the subject Registration
Statement on Form S-6 for the above captioned Trust does not differ from that
which would have been filed pursuant to Rule 497(b) of the Securities Act.
Amendment No. 7 to the Post-Effective, which was the most recent amendment to
the Post-Effective of the Registration Statement, was filed electronically with
the Commission on May 24, 1999.

                                    Very truly yours,

                                    Van Kampen Funds Inc.



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