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Previous: TRANSKARYOTIC THERAPIES INC, S-3, EX-5.1, 2000-12-13 |
Next: TRANSKARYOTIC THERAPIES INC, S-3, EX-23.1, 2000-12-13 |
<PAGE>
Exhibit 12.1
COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES
(DOLLARS IN THOUSANDS)
<TABLE>
<CAPTION>
Years Ended December 31,
-----------------------------------------------------------------------------------------------------------------------------------
1995 1996 1997 1998 1999
-----------------------------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C> <C> <C>
Net income (loss) before provision for income taxes $2,159 $(11,972) $(12,871) $(19,965) $(44,456)
Add:
Fixed Charges 344 356 411 439 1,064
Preferred stock accretion 210 158 - - -
Less:
Interest capitalized during the period - - - - 410
---------------------------------------------------------------
Net income (loss) as adjusted $2,713 $(11,458) $(12,460) $(19,526) $(43,802)
===============================================================
Fixed Charges:
Portion of rent expense representative of interest (1) $ 331 $ 356 $ 411 $ 439 $ 654
Interest expense 13 - - - 410
---------------------------------------------------------------
Total fixed charges $ 344 $ 356 $ 411 $ 439 $ 1,064
===============================================================
Ratio of earnings/(loss) to fixed charges 7.9 - - - -
Deficiency of earnings to fixed charges (2) $ - $(11,972) $(12,871) $(19,965) $(44,866)
===============================================================
<CAPTION>
Nine Months Ended September 30,
-------------------------------------------------------------------------------------------------------
1999 2000
-------------------------------------------------------------------------------------------------------
<S> <C> <C>
Net income (loss) before provision for income taxes $(34,845) $(32,825)
Add:
Fixed Charges 645 1,392
Preferred stock accretion - -
Less:
Interest capitalized during the period 176 781
--------------------------
Net income (loss) as adjusted $(34,376) $(32,214)
==========================
Fixed Charges:
Portion of rent expense representative of interest (1) $ 469 $ 611
Interest expense 176 781
--------------------------
Total fixed charges $ 645 $ 1,392
==========================
Ratio of earnings/(loss) to fixed charges - -
Deficiency of earnings to fixed charges (2) $(35,021) $(33,606)
==========================
</TABLE>
(1) Includes the portion of rent expense for each period presented that is
deemed by management to be the interest component of such rentals.
(2) Deficiency includes capitalized interest of $410 for the year ended
December 31, 1999 and $176 and $781 for the nine months ended September 30,
1999 and 2000, respectively.
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