MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
N-30D, 2000-12-26
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<PAGE>


MORGAN STANLEY DEAN WITTER INSURED
MUNICIPAL INCOME TRUST                                   Two World Trade Center,
LETTER TO THE SHAREHOLDERS October 31, 2000             New York, New York 10048

DEAR SHAREHOLDER:

The U.S. economy continued to register solid economic growth over the 12-month
period ended October 31, 2000. Unemployment reached a 30-year low and real
personal consumption accelerated. The tightening labor market and rising oil
prices led to increased concern that inflationary pressures would surface. In
response, the Federal Reserve Board increased the federal funds rate 100 basis
points in three moves between February and May. The federal funds rate
currently stands at a nine-year high of 6.50 percent. The Fed's shift toward a
tighter monetary policy, which began last year, caused long-term interest rates
to increase in 1999. Early this year, however, the U.S. Treasury announced its
plans to utilize a growing federal budget surplus to reduce its debt. This
announcement precipitated a rally in the bond market. By the end of October
2000, long-term interest rates had declined significantly. Vigilance by the
Federal Reserve in controlling inflation and signs of moderating economic
activity also contributed to more favorable bond market conditions.

MUNICIPAL MARKET CONDITIONS

The long-term insured municipal index, which stood at 6.03 percent at the end
of October 1999, reached a high of 6.19 percent in mid January before declining
to 5.65 percent at the end of October 2000. Because bond prices move inversely
to changes in interest rates, bond prices declined in 1999 but improved this
year. The municipal yield curve flattened 79 basis points during the year and
the pickup for extending maturities from one to 30 years declined from 225
basis points in October 1999 to 146 basis points at the end of this October.

The ratio of municipal yields as a percentage of Treasury yields has
historically been used as a measure of relative value. A rising yield ratio
indicates weaker relative performance by municipals, a declining ratio stronger
performance. Over the past 12 months, this ratio has averaged 98 percent.
Long-term municipal yields have generally followed the trend of U.S. Treasury
yields. For the past three years the high and low ratios have been 100 percent
and 83 percent, respectively.

<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
LETTER TO THE SHAREHOLDERS October 31, 2000, continued

During the first 10 months of 2000, municipal underwriting was 17 percent below
the same period last year. Refunding activity, the most interest-rate-sensitive
component of supply, dropped nearly 60 percent. Approximately 40 percent of the
underwritings were enhanced with bond insurance, versus an average of 50
percent in the previous three years.

  Date            AAA Ins   Tsy     % Relationship
  ----            -------   ---     --------------
12/31/93            5.40%   6.34%       85.17%
01/31/94            5.40    6.24        86.54%
02/28/94            5.80    6.66        87.09%
03/31/94            6.40    7.09        90.27%
04/29/94            6.35    7.32        86.75%
05/31/94            6.25    7.43        84.12%
06/30/94            6.50    7.61        85.41%
07/29/94            6.25    7.39        84.57%
08/31/94            6.30    7.45        84.56%
09/30/94            6.55    7.81        83.87%
10/31/94            6.75    7.96        84.80%
11/30/94            7.00    8.00        87.50%
12/30/94            6.75    7.88        85.66%
01/31/95            6.40    7.70        83.12%
02/28/95            6.15    7.44        82.66%
03/31/95            6.15    7.43        82.77%
04/28/95            6.20    7.34        84.47%
05/31/95            5.80    6.66        87.09%
06/30/95            6.10    6.62        92.15%
07/31/95            6.10    6.86        88.92%
08/31/95            6.00    6.66        90.09%
09/29/95            5.95    6.48        91.82%
10/31/95            5.75    6.33        90.84%
11/30/95            5.50    6.14        89.58%
12/29/95            5.35    5.94        90.07%
01/31/96            5.40    6.03        89.55%
02/29/96            5.60    6.46        86.69%
03/29/96            5.85    6.66        87.84%
04/30/96            5.95    6.89        86.36%
05/31/96            6.05    6.99        86.55%
06/28/96            5.90    6.89        85.63%
07/31/96            5.85    6.97        83.93%
08/30/96            5.90    7.11        82.98%
09/30/96            5.70    6.93        82.25%
10/31/96            5.65    6.64        85.09%
11/29/96            5.50    6.35        86.61%
12/31/96            5.60    6.63        84.46%
01/31/97            5.70    6.79        83.95%
02/28/97            5.65    6.80        83.09%
03/31/97            5.90    7.10        83.10%
04/30/97            5.75    6.94        82.85%
05/30/97            5.65    6.91        81.77%
06/30/97            5.60    6.78        82.60%
07/30/97            5.30    6.30        84.13%
08/31/97            5.50    6.61        83.21%
09/30/97            5.40    6.40        84.38%
10/31/97            5.35    6.15        86.99%
11/30/97            5.30    6.05        87.60%
12/31/97            5.15    5.92        86.99%
01/31/98            5.15    5.80        88.79%
02/28/98            5.20    5.92        87.84%
03/31/98            5.25    5.93        88.53%
04/30/98            5.35    5.95        89.92%
05/29/98            5.20    5.80        89.66%
06/30/98            5.20    5.65        92.04%
07/31/98            5.18    5.71        90.72%
08/31/98            5.03    5.27        95.45%
09/30/98            4.95    5.00        99.00%
10/31/98            5.05    5.16        97.87%
11/30/98            5.00    5.06        98.81%
12/31/98            5.05    5.10        99.02%
01/31/99            5.00    5.09        98.23%
02/28/99            5.10    5.58        91.40%
03/31/99            5.15    5.63        91.47%
04/30/99            5.20    5.66        91.87%
05/31/99            5.30    5.83        90.91%
06/30/99            5.47    5.96        91.78%
07/31/99            5.55    6.10        90.98%
08/31/99            5.75    6.06        94.88%
09/30/99            5.85    6.05        96.69%
10/31/99            6.03    6.16        97.89%
11/30/99            6.00    6.29        95.39%
12/31/99            5.97    6.48        92.13%
01/31/00            6.18    6.49        95.22%
02/29/00            6.04    6.14        98.37%
03/31/00            5.82    5.83        99.83%
04/30/00            5.91    5.96        99.16%
05/31/00            5.91    6.01        98.34%
06/30/00            5.84    5.90        98.98%
07/31/00            5.73    5.78        99.13%
08/31/00            5.62    5.67        99.12%
09/30/00            5.74    5.89        97.45%
10/31/00            5.65    5.79        97.58%

Source: Municipal Market Data - A Division of Thomson Financial Group and
        Bloomberg L.P.




PERFORMANCE

During the 12-month period ended October 31, 2000, the net asset value (NAV) of
Morgan Stanley Dean Witter Insured Municipal Income Trust (IIM) increased from
$13.69 to $14.44 per share. Based on this change, plus a reinvestment of
tax-free dividends totaling $0.8625 per share, the Trust's total NAV return was
12.75 percent. IIM's value on the New York Stock Exchange (NYSE) decreased from
$13.25 to $12.8125 per share during this period. Based on this change plus
reinvestment of tax-free dividends, IIM's total market return was 3.29 percent.
As of October 31, 2000, IIM's share price was at a 11.27 percent discount to
its NAV.

                                        2
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
LETTER TO THE SHAREHOLDERS October 31, 2000, continued

Monthly dividends for the fourth quarter of 2000, were declared in September.
Beginning with the October payment, the monthly dividend was reduced from
$0.0725 to $0.065 per share. The new dividend reflects current earning and the
Trust's level of undistributed net investment income which was $0.051 per share
on October 31, 2000, versus $0.117 per share 12 months earlier.

PORTFOLIO STRUCTURE

The Trust's investments were diversified among 13 long-term sectors and 77
credits. Issues in the refunded bond category comprised 7 percent of net
assets. These bonds have been refinanced and will be redeemed on the dates
shown in the portfolio. At the end of October, the portfolio's average maturity
was 19 years. Average duration, a measure of portfolio sensitivity to interest
rates, was 7.6 years. Generally, bonds with longer durations have greater
volatility. The accompanying charts and tables provide current information on
the portfolio's credit enhancements, maturity distribution and sector
diversification. Optional call provisions and their respective cost (book)
yields by year are also shown.

THE IMPACT OF LEVERAGING

As discussed in previous shareholder reports, the total income available for
distribution to common shareholders includes incremental income provided by the
Trust's outstanding Auction Rate Preferred shares (ARPS). ARPS dividends
reflect prevailing short-term interest rates on maturities normally ranging
from one week to one year. Incremental income to common shareholders depends on
two factors. The first factor is the amount of ARPS outstanding, while the
second is the spread between the portfolio's cost yield and ARPS expenses (ARPS
auction rate and expenses). The greater the spread and amount of ARPS
outstanding, the greater the amount of incremental income available for
distribution to common shareholders. The level of net investment income
available for distribution to common shareholders varies with the level of
short-term interest rates. ARPS leverage also increases the price volatility of
common shares and has the effect of extending portfolio duration.

During the 12-month period, ARPS leverage contributed approximately $0.07 per
share to common share earnings. The Trust's five ARPS series totaling $155
million represented 28 percent of net assets. The yield on IIM's three weekly
ARPS series ranged between 3.00 and 5.30 percent. Yields on series with
rollovers in July and September 2001 are 4.45 and 4.32 percent, respectively.
In comparison, the yield on 1-year municipal notes increased from 3.77 percent
at the end of October 1999 to 4.19 percent at the end of this October.

                                        3
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
LETTER TO THE SHAREHOLDERS October 31, 2000, continued

LOOKING AHEAD

The slower pace of economic growth and moderate inflation have caused the bond
market to anticipate a shift by the Federal Reserve Board to a neutral bias in
its monetary policy and the possibility of easing in 2001. This should create a
favorable environment for municipal bonds.

The Trust's procedure for reinvestment of all dividends and distributions on
common shares is through purchases in the open market. This method helps
support the market value of the Trust's shares. In addition, we would like to
remind you that the Trustees have approved a procedure whereby the Trust may,
when appropriate, purchase shares in the open market or in privately negotiated
transactions at a price not above market value or net asset value, whichever is
lower at the time of purchase. The Trust may also utilize procedures to reduce
or eliminate the amount of outstanding ARPS, including their purchase in the
open market or in privately negotiated transactions. During the fiscal period
ended October 31, 2000, the Trust purchased and retired 872,400 shares of
common stock at a weighted average market discount of 7.07 percent.

We appreciate your ongoing support of Morgan Stanley Dean Witter Insured
Municipal Income Trust and look forward to continuing to serve your investment
needs.

Very truly yours,

/s/ Charles A. Fiumefreddo                  /s/ Mitchell M. Merin

CHARLES A. FIUMEFREDDO                      MITCHELL M. MERIN
Chairman of the Board                       President

                                        4
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
LETTER TO THE SHAREHOLDERS October 31, 2000, continued

                                   [BAR GRAPH]

                  LARGEST SECTORS AS OF OCTOBER 31, 2000
                  (% OF NET ASSETS)

                  WATER AND SEWER          17%
                  ELECTRIC                 13%
                  TRANSPORTATION           12%
                  HOSPITAL                 11%
                  IDR/PCR*                 10%
                  MORTGAGE                  8%
                  GENERAL OBLIGATION        7%
                  REFUNDED                  7%

                  * INDUSTRIAL DEVELOPMENT/POLLUTION CONTROL REVENUE.
                    PORTFOLIO STRUCTURE IS SUBJECT TO CHANGE.

                                    [PIE CHART]

                  CREDIT EXHANCEMENTS AS OF OCTOBER 31, 2000
                  (% OF TOTAL LONG-TERM PORTFOLIO)

                  MBIA      37%
                  FGIC      23%
                  Ambac     21%
                  FSA       19%

                  PORTFOLIO STRUCTURE IS SUBJECT TO CHANGE.

                                   [BAR GRAPH]

                            DISTRIBUTION BY MATURITY
                               (% OF NET ASSETS)

                                                         WEIGHTED AVERAGE
                                                         MATURITY: 19 YEARS
                              UNDER 1 YEAR    3.0%
                              1-5 YEARS       2.6%
                              5-10 YEARS      3.4%
                              10-20 YEARS    48.1%
                              20-30 YEARS    36.4%
                              30+ YEARS       4.2%

                   PORTFOLIO STRUCTURE IS SUBJECT TO CHANGE.

                                        5
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
LETTER TO THE SHAREHOLDERS October 31, 2000, continued

                      CALL AND COST (BOOK) YIELD STRUCTURE
                         (BASED ON LONG-TERM PORTFOLIO)
                                OCTOBER 31, 2000

                                                        WEIGHTED AVERAGE
                                                        CALL PROTECTION: 6 YEARS
                                 BONDS CALLABLE

                                   [BAR CHART]

                                 2000       0%
                                 2001       2%
                                 2002      14%
                                 2003      48%
                                 2004       3%
                                 2005       1%
                                 2006       1%
                                 2007       1%
                                 2008       4%
                                 2009       6%
                                 2010+     20%


                                                        WEIGHTED AVERAGE
                                                        BOOK YIELD: 5.8%
                               COST (BOOK) YIELD*

                                   [BAR CHART]

                                 2000
                                 2001      6.0%
                                 2002      5.8%
                                 2003      5.9%
                                 2004      5.8%
                                 2005      5.9%
                                 2006      5.9%
                                 2007      5.6%
                                 2008      5.3%
                                 2009      5.6%
                                 2010+     5.7%

* COST OR "BOOK" YIELD IS THE ANNUAL INCOME EARNED ON A PORTFOLIO INVESTMENT
  BASED ON ITS ORIGINAL PURCHASE PRICE BEFORE TRUST OPERATING EXPENSES. FOR
  EXAMPLE, THE TRUST IS EARNING A BOOK YIELD OF 6.0% ON 2% OF THE LONG-TERM
  PORTFOLIO THAT IS CALLABLE IN 2001.

  PORTFOLIO STRUCTURE IS SUBJECT TO CHANGE.


                                        6
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
RESULTS OF ANNUAL MEETING (unaudited)

                                      * * *

On October 24, 2000, an annual meeting of the Trust's shareholders was held for
the purpose of voting on two separate matters, the results of which were as
follows:

(1)  ELECTION OF TRUSTEES:

Edwin J. Garn
  For .........................................    20,823,995
  Withheld ....................................       351,762

James F. Higgins
  For .........................................    20,827,287
  Withheld ....................................       348,470

Michael E. Nugent
  For .........................................    20,830,783
  Withheld ....................................       344,974

Philip J. Purcell
  For .........................................    20,831,804
  Withheld ....................................       343,953

The following Trustees were not standing for reelection at this meeting:

Michael Bozic, Charles A. Fiumefreddo, Wayne E. Hedien, Dr. Manuel H. Johnson
and John L. Schroeder.

(2)  RATIFICATION OF THE SELECTION OF DELOITTE & TOUCHE LLP AS INDEPENDENT
     AUDITORS:

<TABLE>
<S>                   <C>
  For .........................................    20,707,268
  Against .....................................       132,680
  Abstain .....................................       335,809
</TABLE>


                                        7
<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000

<TABLE>
<CAPTION>
 PRINCIPAL
 AMOUNT IN                                                                                    COUPON    MATURITY
 THOUSANDS                                                                                     RATE       DATE          VALUE
-----------                                                                                ----------- -----------  ------------
<S>        <C>                                                                                <C>      <C>         <C>
            TAX-EXEMPT MUNICIPAL BONDS (94.7%)
            General Obligation (7.4%)
            District of Columbia,
 $   5,000  Refg Ser 1993 B (Ambac) ......................................................     5.50  %  06/01/09    $  5,204,400
     6,000  Refg Ser 1993 B (FSA) ........................................................     5.50     06/01/10       6,239,820
     7,000  Cook County, Ilinois, Ser B (FGIC) ...........................................     5.50     11/15/22       6,816,810
     5,000  River Rouge School District, Michigan, 1993 Bldg & Site Unltd Tax (FSA) ......     5.625    05/01/22       5,019,700
     3,000  Vicksburg Community Schools, Michigan, 1993 Refg (MBIA) ......................     5.625    05/01/20       3,007,680
     6,000  Clark County Sanitation District, Nevada, Refg 1993 (FGIC) ...................     5.70     07/01/12       6,148,200
     8,000  Washoe County, Nevada, Reno - Sparks Convention Ltd Tax Ser 1993 A
            (FGIC) .......................................................................     5.75     07/01/22       8,067,600
 ---------                                                                                                          ------------
    40,000                                                                                                            40,504,210
 ---------                                                                                                          ------------
            Educational Facilities Revenue (3.0%)
     4,000  Alabama State University, General Tuition & Fee Ser 1993 (MBIA) ..............     5.70     05/01/15       4,078,680
     3,000  District of Columbia, American Association for the Advancement of
            Science Ser 1997 (Ambac) .....................................................     5.125    01/01/27       2,774,340
     4,000  Illinois Educational Facilities Authority, DePaul University Refg Ser 1997
            (Ambac) ......................................................................     5.50     10/01/19       3,971,920
     3,000  Indiana University, Student Fee Ser J (FGIC) .................................     5.00     08/01/18       2,822,040
     2,500  Rhode Island Health & Educational Building Corporation, Providence College
            Ser 1993 (MBIA) ..............................................................     5.60     11/01/15       2,527,550
 ---------                                                                                                          ------------
    16,500                                                                                                            16,174,530
 ---------                                                                                                          ------------
            Electric Revenue (13.1%)
     8,000  Redding, California, Ser 1993 A COPs (FGIC) ..................................     6.623++  06/01/19       8,140,000
            Massachusetts Municipal Wholesale Electric Company,
     5,000  1993 Ser A (Ambac) ...........................................................     5.00     07/01/10       5,034,800
     5,000  1993 Ser A (Ambac) ...........................................................     6.27++   07/01/18       4,656,250
    10,000  North Carolina Municipal Power Agency #1, Catawba Ser 1993 (MBIA) ............     6.42++   01/01/20       9,962,500
     4,000  Piedmont Municipal Power Agency, South Carolina, Refg Ser 1993 (MBIA) ........     5.375    01/01/25       3,912,360
    10,000  South Carolina Public Service Authority, 1993 Refg Ser A (MBIA) ..............     5.50     07/01/21       9,853,500
    10,000  Lower Colorado River Authority, Texas, Refg Ser 1999 A (FSA) .................     5.875    05/15/16      10,448,800

    10,000  Washington Public Power Supply System, Nuclear Proj #1 Refg Ser 1993 A
            (MBIA) .......................................................................     5.70     07/01/17      10,113,300
    10,000  Wisconsin Public Power Incorporated, Refg Ser 1993 A (Ambac) .................     5.25     07/01/21       9,562,000
 ---------                                                                                                          ------------
    72,000                                                                                                            71,683,510
 ---------                                                                                                          ------------
            Hospital Revenue (10.9%)
     5,000  Mesa Industrial Development Authority, Arizona, Discovery Health
            Ser 1999 A (MBIA) ............................................................     5.875    01/01/16       5,215,350
     2,100  District of Columbia, Children's Hospital Refg Ser 1992 A (FGIC) .............     6.25     07/15/10       2,186,793
     5,000  Sarasota County Public Hospital Board, Florida, Sarasota Memorial Hospital
            Refg Ser 1998 B (MBIA) .......................................................     5.25     07/01/24       4,803,300
     3,000  Indiana Health Facilities Financing Authority, Deaconess Hospital Inc
            Refg Ser 1993 (MBIA) .........................................................     5.75     03/01/15       3,038,670

</TABLE>
                        See Notes to Financial Statements


                                       8


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000, continued


<TABLE>
<CAPTION>
 PRINCIPAL
 AMOUNT IN                                                                                     COUPON     MATURITY
 THOUSANDS                                                                                      RATE        DATE         VALUE
-----------                                                                                 ------------ ----------  ------------
<S>        <C>                                                                                <C>        <C>        <C>
 $   5,000  Kentucky Economic Development Finance Authority, St Elizabeth Medical
            Center Inc Ser 1993 A (FGIC) ..................................................    6.00 %     12/01/22   $  5,159,550
     3,935  Maine Health & Higher Educational Facilities Authority, Ser 1993 A (FSA) ......    5.50       07/01/23      3,820,609
     5,500  Massachusetts Health & Educational Facilities Authority, Lahey Clinic
            Medical Center Ser B (MBIA) ...................................................    5.625      07/01/15      5,554,505
     5,000  Missouri Health & Educational Facilities Authority, SSM Health Care
            Ser 1998 A (MBIA) .............................................................    5.00       06/01/22      4,665,800
     4,000  Washington County Hospital Authority, Pennsylvania, Washington Hospital
            Ser 1993 (Ambac) ..............................................................    5.625      07/01/23      3,941,720
     4,000  Chattanooga-Hamilton County Hospital Authority, Tennessee, Erlanger
            Medical Center Refg Ser 1993 (FSA) ............................................    5.50       10/01/13      4,047,840
            Amarillo Health Facilities Corporation, Texas,
     3,020  Baptist St Anthony's Hospital Ser 1998 (FSA) ..................................    5.50       01/01/16      3,050,744
     5,075  Baptist St Anthony's Hospital Ser 1998 (FSA) ..................................    5.50       01/01/17      5,096,213
     4,000  Washington Health Care Facilities Authority, Swedish Health Ser 1998
            (Ambac) .......................................................................    5.125      11/15/22      3,698,200
     5,500  Wisconsin Health & Educational Facilities Authority, Sisters of the Sorrowful
            Mother Health Care Ser AA (MBIA) ..............................................    6.25       06/01/20      5,610,715
 ---------                                                                                                           ------------
    60,130                                                                                                             59,890,009
 ---------                                                                                                           ------------
            Industrial Development/Pollution Control Revenue (10.0%)
     7,500  Adams County, Colorado, Public Service Co of Colorado Refg 1993 Ser A
            (MBIA) ........................................................................    5.875      04/01/14      7,672,725
     4,000  St Johns County Industrial Development Authority, Florida, Professional Golf
            Hall of Fame Ser 1996 (MBIA) ..................................................    5.875      09/01/23      4,104,720
     5,000  Hawaii Department of Budget and Finance, Hawaiian Electric Co Ser 1999 C
            (AMT) (Ambac) .................................................................    6.20       11/01/29      5,173,950
    12,000  Indiana Development Finance Authority, PSI Energy Inc Ser 1993 B (AMT)
            (MBIA) ........................................................................    5.75       02/15/28     11,722,680
     4,900  Monroe County, Michigan, Detroit Edison Co Ser CC (AMT) (MBIA) ................    6.55       06/01/24      5,153,281
     5,400  Forsyth, Montana, Puget Sound Power & Light Co Ser 1993 (MBIA) ................    5.875      04/01/20      5,457,078
            Washoe County, Nevada, Sierra Pacific Power Co
     3,000  Ser 1987 (Ambac) ..............................................................    6.30       12/01/14      3,113,010
     5,000  Ser 1987 (AMT) (MBIA) .........................................................    6.65       06/01/17      5,240,100
     3,000  New York State Energy Research & Development Authority, Brooklyn
            Union Gas Co 1991 Ser A & B (AMT) (MBIA) ......................................    6.931++    07/08/26      2,812,500
     4,000  Brazos River Authority, Texas, Texas Utilities Electric Co Ser 1993 A
            (AMT) (Ambac) .................................................................    6.05       04/01/25      4,044,120
 ---------                                                                                                           ------------
    53,800                                                                                                             54,494,164
 ---------                                                                                                           ------------
            Mortgage Revenue - Multi-Family (0.7%)
     4,000  West Virginia Housing Development Fund, Ser A (Ambac) .........................    5.65       11/01/21      3,946,800
 ---------                                                                                                           ------------
</TABLE>

                       See Notes to Financial Statements


                                       9




<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000, continued


<TABLE>
<CAPTION>
 PRINCIPAL
 AMOUNT IN                                                                                  COUPON     MATURITY
 THOUSANDS                                                                                   RATE        DATE         VALUE
-----------                                                                              ------------ ----------  ------------
<S>         <C>                                                                          <C>          <C>        <C>
            Mortgage Revenue - Single Family (7.1%)
 $  15,005  Connecticut Housing Finance Authority, 1992 Ser A-2 (AMT)
            (Secondary FSA) ............................................................ 6.05 %       11/15/25    $ 15,121,889
     1,195  Maine Housing Authority, Mortgage Purchase 1990 Ser A-6 (AMT)
            (Secondary MBIA) ........................................................... 6.35         11/15/22       1,197,749
    12,500  New Jersey Housing & Mortgage Finance Agency, Home Buyer 1990 Ser F-3
            (AMT) (MBIA) ............................................................... 5.95         04/01/25      12,584,500
    10,000  Virginia Housing Development Authority, 1992 Ser B (AMT) (Secondary FSA).... 6.30         01/01/27      10,162,000
 ---------                                                                                                        ------------
    38,700                                                                                                          39,066,138
 ---------                                                                                                        ------------
            Public Facilities Revenue (1.8%)
    10,000  Marion County Convention & Recreational Facilities Authority, Indiana,
 ---------
            Excise Tax Refg Ser 1993 A (Ambac) ......................................... 5.50         06/01/21       9,842,200
                                                                                                                  ------------
            Student Loan Revenue (3.3%)
    18,000  Pennsylvania Higher Education Assistance Agency, 1988 Ser D (AMT)
 ---------
            (Ambac) .................................................................... 6.05         01/01/19      18,250,380
                                                                                                                  ------------
            Transportation Facilities Revenue (12.3%)
     5,000  Tucson, Arizona, Street & Highway Jr Lien Refg Ser 1993 (MBIA) ............. 5.50         07/01/12       5,112,950
     9,000  Long Beach California, Harbor Refg Ser 1998 A (AMT) (FGIC) ................. 6.00         05/15/18       9,789,030
     5,000  Chicago, Illinois, Chicago-O'Hare Int'l Airport Second Lien Refg 1993
            Ser A (AMT) (MBIA) ......................................................... 5.60         01/01/18       4,924,850
     4,000  Illinois Toll Highway Authority, Priority Refg 1998 Ser A (FSA) ............ 5.50         01/01/15       4,118,920
     3,000  Kentucky Turnpike Authority, Econ Dev Road Revitalization Refg Ser 1993
            (Ambac) .................................................................... 5.50         07/01/11       3,066,540
     2,500  Minneapolis-St Paul Metropolitan Airports Commission, Minnesota,
            Ser 1999 A (FGIC) .......................................................... 5.125        01/01/31       2,331,250
     1,250  Clark County, Nevada, Las Vegas-McCarran Int'l Airport, Sub Lien
            Ser 1999 A (MBIA) .......................................................... 6.00         07/01/29       1,298,800
    12,000  Nevada Department of Business & Industry, Las Vegas Monorail, 1st Tier
            Ser 2000 (Ambac) ........................................................... 5.375        01/01/40      11,319,120
     9,000  Pennsylvania Turnpike Commission, Refg Ser O 1992 (FGIC) ................... 5.50         12/01/17       9,025,560
     5,000  South Carolina Transportation Infrastructure Bank, Ser 1999 A (Ambac) ...... 5.50         10/01/16       5,068,400
     4,000  Salt Lake City, Utah, Airport Refg Ser 1993 B (FGIC) ....................... 5.875        12/01/18       4,035,560
     2,000  Richmond Metropolitan Authority, Virginia, Expressway 1992 Ser B (FGIC) .... 6.25         07/15/22       2,062,300
     5,000  Port of Seattle, Washington, Ser B (AMT) (MBIA) ............................ 5.625        02/01/24       4,894,800
 ---------                                                                                                        ------------
    66,750                                                                                                          67,048,080
 ---------                                                                                                        ------------
            Water & Sewer Revenue (16.7%)
     2,000  Honolulu City and County, Hawaii, Wastewater Sr Ser 1998 (FGIC) ............ 4.75         07/01/28       1,712,960
    15,000  Central Lake County Joint Action Water Agency, Illinois, Refg Ser 1993
            (FGIC) ..................................................................... 5.375        05/01/20      14,619,900
    10,000  Louisville & Jefferson County Metropolitan Sewer District, Kentucky,
            Ser 1993 (MBIA) ............................................................ 5.30         05/15/19       9,735,100
     2,470  Detroit, Michigan, Sewage Refg Ser 1993 A (FGIC) ........................... 5.70         07/01/13       2,531,701
     5,000  Grand Rapids, Michigan, Sewer Impr & Refg Ser 1998 A (FGIC) ................ 4.75         01/01/28       4,347,300
     5,000  Cleveland, Ohio, Waterworks Impr & Refg 1998 Ser I (FSA) ................... 5.00         01/01/23       4,602,350
</TABLE>

                        See Notes to Financial Statements


                                       10


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000, continued


<TABLE>
<CAPTION>
 PRINCIPAL
 AMOUNT IN                                                                                    COUPON       MATURITY
 THOUSANDS                                                                                     RATE          DATE         VALUE
-----------                                                                                 ----------  -------------  ------------
<S>         <C>                                                                                <C>        <C>         <C>
 $   4,000  Allegheny County Sanitary Authority, Pennsylvania, Sewer Ser 2000 (MBIA) ......     5.50 %     12/01/24    $  3,952,440
     5,000  Philadelphia, Pennsylvania, Water & Wastewater Ser 1998 (Ambac) ...............     5.25       12/15/14       5,049,450
            Houston, Texas,
    15,000  Water & Sewer 1992 Ser C (MBIA) ...............................................     5.75       12/01/15      15,288,150
    10,000  Water & Sewer Jr Lien Refg Ser 2000 B (FGIC) ..................................     5.25       12/01/30       9,437,800
            Seattle, Washington,
    10,000  Sewer Refg Ser Y (FGIC) .......................................................     5.70       01/01/15      10,121,700
     5,000  Sewer Refg Ser X (FGIC) .......................................................     5.50       01/01/16       5,019,900
     5,000  West Virginia Water Development Authority, Loan Program II Refg Ser A-11
            (FSA) .........................................................................     5.50       11/01/23       4,916,750
 ---------                                                                                                             ------------
    93,470                                                                                                               91,335,501
 ---------                                                                                                             ------------
            Other Revenue (1.1%)
     3,000  Florida Department of Environmental Protection, Preservation 2000
            Ser 1999 A (FGIC) .............................................................     5.25       07/01/13       3,040,650
     3,000  Alexandria Industrial Development Authority, Virginia, Institute for
            Defense Analysis Ser 2000A (Ambac) ............................................     5.90       10/01/30       3,051,720
 ---------                                                                                                             ------------
     6,000                                                                                                                6,092,370
 ---------                                                                                                             ------------
            Refunded (7.3%)
    13,700  Louisiana Public Facilities Authority, Our Lady of the Lake Regional Medical
            Center Ser 1993 D & E (FSA) ...................................................     5.90       05/28/04+     14,440,211
     6,065  Maine Health & Higher Educational Facilities Authority, Ser 1993 A (FSA)
            (ETM) .........................................................................     5.50       07/01/23       5,933,814
     5,000  Allegheny County Hospital Development Authority, Pennsylvania,
            Pittsburgh Mercy Health Ser 1996 (Ambac) (ETM) ................................     5.625      08/15/18       5,060,800
    10,000  Rhode Island Depositors Economic Protection Corporation, Refg 1992 Ser B
            (MBIA) (ETM) ..................................................................     6.00       08/01/17      10,387,300
     4,360  Piedmont Municipal Power Agency, South Carolina, Refg Ser 1993 (MBIA)
            (ETM) .........................................................................     5.375      01/01/25       4,290,109
 ---------                                                                                                             ------------
    39,125                                                                                                               40,112,234
 ---------                                                                                                             ------------
   518,475  TOTAL TAX-EXEMPT MUNICIPAL BONDS (Cost $510,411,485) ........................                               518,440,126
 ---------                                                                                                             ------------
</TABLE>

                        See Notes to Financial Statements


                                       11


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000, continued


<TABLE>
<CAPTION>
 PRINCIPAL
 AMOUNT IN                                                                                COUPON       MATURITY
 THOUSANDS                                                                                 RATE          DATE           VALUE
-----------                                                                           -------------- ------------ ---------------
<S>         <C>                                                                       <C>            <C>          <C>
            SHORT-TERM TAX-EXEMPT MUNICIPAL OBLIGATIONS (3.0%)
 $   5,000  Massachusetts Municipal Wholesale Electric Company, 1993 Ser A (Ambac)
            (Auction reset 01/02/01) ................................................ 4.63**%          07/01/18    $  5,000,000
    10,000  North Carolina Municipal Power Agency #1, Catawba Ser 1993 (MBIA)
            (Auction reset 01/02/01) ................................................ 4.78**           01/01/20      10,000,000
     1,300  Harris County Health Facilities Development Corporation, Texas, Methodist
 ---------
            Hospital Ser 1994 (Demand 11/01/00) ..................................... 4.60*            12/01/25       1,300,000
                                                                                                                   ------------
    16,300  TOTAL SHORT-TERM TAX-EXEMPT MUNICIPAL OBLIGATIONS (Cost $16,300,000) ..............................      16,300,000
 ---------                                                                                                         ------------
 $ 534,775  TOTAL INVESTMENTS (Cost $526,711,485) (a) ............................................         97.7%    534,740,126
 =========
            OTHER ASSETS IN EXCESS OF LIABILITIES ................................................          2.3      12,772,630
                                                                                                          -----    ------------
            NET ASSETS ...........................................................................        100.0%   $547,512,756
                                                                                                          =====    ============
</TABLE>

---------------
AMT    Alternative Minimum Tax.
COPs   Certificates of Participation.
ETM    Escrowed to maturity.
+      Prerefunded to call date shown.
++     Current coupon rate for residual interest bond. This rate resets
       periodically as the auction rate on the related short-term
       securities fluctuates.
*      Current coupon of variable rate demand obligation.
**     Current auction rate.
(a)    The aggregate cost for federal income tax purposes approximates
       the aggregate cost for book purposes.
       The aggregate gross unrealized appreciation is $10,384,900 and the
       aggregate gross unrealized
       depreciation is $2,356,259, resulting in net unrealized appreciation of
       $8,028,641.


Bond Insurance:
---------------
Ambac  Ambac Assurance Corporation.
FGIC   Financial Guaranty Insurance Company.
FSA    Financial Security Assurance Inc.
MBIA   Municipal Bond Investors Assurance Corporation.

                        See Notes to Financial Statements


                                       12


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
PORTFOLIO OF INVESTMENTS October 31, 2000, continued




                        GEOGRAPHIC SUMMARY OF INVESTMENTS
                Based on Market Value as a Percent of Net Assets

<TABLE>
<S>                                 <C>            <C>                                  <C>
   Alabama ......................       0.7%       Maine ........................       2.0%
   Arizona   ....................       1.9        Massachusetts ................       3.7
   California ...................       3.3        Michigan   ...................       3.7
   Colorado .....................       1.4        Minnesota ....................       0.4
   Connecticut ..................       2.8        Missouri .....................       0.9
   District of Columbia .........       3.0        Montana ......................       1.0
   Florida ......................       2.2        Nevada .......................       6.4
   Hawaii .......................       1.3        New Jersey  ..................       2.3
   Illinois  ....................       6.3        New York .....................       0.5
   Indiana ......................       5.0        North Carolina ...............       3.6
   Kentucky .....................       3.3        Ohio .........................       0.8
   Louisiana  ...................       2.6        Pennsylvania .................       8.3


</TABLE>
<TABLE>
<S>                                 <C>
   Rhode Island .................       2.4%
   South Carolina ...............       4.2
   Tennessee ....................       0.7
   Texas ........................       8.9
   Utah   .......................       0.7
   Virginia  ....................       2.8
   Washington ...................       6.2
   West Virginia ................       1.6
   Wisconsin ....................       2.8
                                       ----
   Total ........................      97.7%
                                       ====
</TABLE>

                        See Notes to Financial Statements


                                       13


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
FINANCIAL STATEMENTS

STATEMENT OF ASSETS AND LIABILITIES
October 31, 2000

<TABLE>
<CAPTION>
ASSETS:
<S>                                                  <C>
Investments in securities, at value
   (cost $526,711,485)............................    $534,740,126
Cash .............................................          77,400
Receivable for:
     Interest ....................................      10,051,102
     Investments sold ............................       3,000,000
Prepaid expenses .................................         293,244
                                                      ------------
    TOTAL ASSETS .................................     548,161,872
                                                      ------------
LIABILITIES:
Payable for:
     Dividends to preferred shareholders .........         344,808
     Investment management fee ...................         167,471
     Common shares of beneficial interest
        repurchased ..............................          25,560
Accrued expenses .................................         111,277
                                                      ------------
    TOTAL LIABILITIES ............................         649,116
                                                      ------------
    NET ASSETS ...................................    $547,512,756
                                                      ============
COMPOSITION OF NET ASSETS:
Preferred shares of beneficial interest
   (1,000,000 shares authorized of
   non-participating $.01 par value, 3,100
   shares outstanding) ...........................    $155,000,000
                                                      ------------
Common shares of beneficial interest
   (unlimited shares authorized of
   $.01 par value, 27,191,713 shares
   outstanding) ..................................     392,059,812
Net unrealized appreciation ......................       8,028,641
Accumulated undistributed net investment
   income ........................................       1,387,035
Accumulated net realized loss ....................      (8,962,732)
                                                      ------------
    NET ASSETS APPLICABLE TO COMMON
    SHAREHOLDERS .................................     392,512,756
                                                      ------------
    TOTAL NET ASSETS .............................    $547,512,756
                                                      ============
NET ASSET VALUE PER COMMON SHARE
($392,512,756 divided by 27,191,713 common
shares outstanding) ..............................          $14.44
                                                            ======
</TABLE>




STATEMENT OF OPERATIONS
For the year ended October 31, 2000

<TABLE>
<CAPTION>
NET INVESTMENT INCOME:
<S>                                               <C>
INTEREST INCOME ...............................    $30,814,958
                                                   -----------
EXPENSES
Investment management fee .....................      1,895,026
Auction commission fees .......................        507,751
Transfer agent fees and expenses ..............        102,730
Professional fees .............................         91,840
Shareholder reports and notices ...............         61,662
Auction agent fees ............................         41,092
Registration fees .............................         33,181
Trustees' fees and expenses ...................         16,537
Custodian fees ................................         14,911
Other .........................................         45,904
                                                   -----------
    TOTAL EXPENSES ............................      2,810,634
Less: expense offset ..........................        (14,840)
                                                   -----------
    NET EXPENSES ..............................      2,795,794
                                                   -----------
    NET INVESTMENT INCOME .....................     28,019,164
                                                   -----------
NET REALIZED AND UNREALIZED GAIN:
Net realized gain .............................        954,002
Net change in unrealized depreciation .........     20,377,877
                                                   -----------
    NET GAIN ..................................     21,331,879
                                                   -----------
NET INCREASE ..................................    $49,351,043
                                                   ===========
</TABLE>



                        See Notes to Financial Statements


                                       14


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
FINANCIAL STATEMENTS, continued

STATEMENT OF CHANGES IN NET ASSETS



<TABLE>
<CAPTION>
                                                                  FOR THE YEAR         FOR THE YEAR
                                                                      ENDED               ENDED
                                                                OCTOBER 31, 2000     OCTOBER 31, 1999
                                                               ------------------   -----------------
<S>                                                            <C>                  <C>
INCREASE (DECREASE) IN NET ASSETS:
OPERATIONS:
Net investment income ......................................     $  28,019,164        $  28,472,222
Net realized gain ..........................................           954,002            1,342,564
Net change in unrealized appreciation/depreciation .........        20,377,877          (51,093,174)
                                                                 -------------        -------------
   NET INCREASE (DECREASE) .................................        49,351,043          (21,278,388)
                                                                 -------------        -------------
DIVIDENDS TO SHAREHOLDERS FROM NET INVESTMENT INCOME:
Preferred ..................................................        (6,116,742)          (5,349,191)
Common .....................................................       (23,811,275)         (23,908,726)
                                                                 -------------        -------------
   TOTAL DIVIDENDS .........................................       (29,928,017)         (29,257,917)
                                                                 -------------        -------------
Decrease from transactions in common shares of
  beneficial interest ......................................       (11,187,324)          (4,993,279)
                                                                 -------------        -------------
   NET INCREASE (DECREASE) .................................         8,235,702          (55,529,584)
NET ASSETS:
Beginning of period ........................................       539,277,054          594,806,638
                                                                 -------------        -------------
   END OF PERIOD
   (Including undistributed net investment income of
   $1,387,035 and $3,295,888, respectively).................     $ 547,512,756        $ 539,277,054
                                                                 =============        =============
</TABLE>

                        See Notes to Financial Statements


                                       15


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
NOTES TO FINANCIAL STATEMENTS October 31, 2000

1. ORGANIZATION AND ACCOUNTING POLICIES

Morgan Stanley Dean Witter Insured Municipal Income Trust (the "Trust") is
registered under the Investment Company Act of 1940, as amended, as a
diversified, closed-end management investment company. The Trust's investment
objective is to provide current income which is exempt from federal income tax.
The Trust was organized as a Massachusetts business trust on March 12, 1992 and
commenced operations on February 26, 1993.

The preparation of financial statements in accordance with generally accepted
accounting principles requires management to make estimates and assumptions
that affect the reported amounts and disclosures. Actual results could differ
from those estimates.

The following is a summary of significant accounting policies:

A. VALUATION OF INVESTMENTS - Portfolio securities are valued by an outside
independent pricing service approved by the Trustees. The pricing service has
informed the Trust that in valuing the portfolio securities, it uses both a
computerized matrix of tax-exempt securities and evaluations by its staff, in
each case based on information concerning market transactions and quotations
from dealers which reflect the bid side of the market each day. The portfolio
securities are thus valued by reference to a combination of transactions and
quotations for the same or other securities believed to be comparable in
quality, coupon, maturity, type of issue, call provisions, trading
characteristics and other features deemed to be relevant. Short-term debt
securities having a maturity date of more than sixty days at time of purchase
are valued on a mark-to-market basis until sixty days prior to maturity and
thereafter at amortized cost based on their value on the 61st day. Short-term
debt securities having a maturity date of sixty days or less at the time of
purchase are valued at amortized cost.

B. ACCOUNTING FOR INVESTMENTS - Security transactions are accounted for on the
trade date (date the order to buy or sell is executed). Realized gains and
losses on security transactions are determined by the identified cost method.
The Trust amortizes premiums and accretes discounts over the life of the
respective securities. Interest income is accrued daily.

C. FEDERAL INCOME TAX STATUS - It is the Trust's policy to comply with the
requirements of the Internal Revenue Code applicable to regulated investment
companies and to distribute all of its taxable and nontaxable income to its
shareholders. Accordingly, no federal income tax provision is required.

D. DIVIDENDS AND DISTRIBUTIONS TO SHAREHOLDERS - The Trust records dividends
and distributions to its shareholders on the ex-dividend date. The amount of
dividends and distributions from net investment income and net realized capital
gains are determined in accordance with federal income tax regulations


                                       16


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
NOTES TO FINANCIAL STATEMENTS October 31, 2000, continued

which may differ from generally accepted accounting principles. These
"book/tax" differences are either considered temporary or permanent in nature.
To the extent these differences are permanent in nature, such amounts are
reclassified within the capital accounts based on their federal tax-basis
treatment; temporary differences do not require reclassification. Dividends and
distributions which exceed net investment income and net realized capital gains
for tax purposes are reported as distributions of paid-in-capital.


2. INVESTMENT MANAGEMENT AGREEMENT

Pursuant to an Investment Management Agreement, the Trust pays the Investment
Manager a management fee, calculated weekly and payable monthly, by applying
the annual rate of 0.35% to the Trust's weekly net assets.


3. SECURITY TRANSACTIONS AND TRANSACTIONS WITH AFFILIATES

The cost of purchases and proceeds from sales of portfolio securities,
excluding short-term investments, for the year ended October 31, 2000
aggregated $60,469,763 and $59,936,642 respectively.

Morgan Stanley Dean Witter Trust FSB, an affiliate of the Investment Manager,
is the Trust's transfer agent. At October 31, 2000, the Trust had transfer
agent fees and expenses payable of approximately $1,800.

The Trust has an unfunded noncontributory defined benefit pension plan covering
all independent Trustees of the Trust who will have served as independent
Trustees for at least five years at the time of retirement. Benefits under this
plan are based on years of service and compensation during the last five years
of service. Aggregate pension costs for the year ended October 31, 2000
included in Trustees' fees and expenses in the Statement of Operations amounted
to $5,062. At October 31, 2000, the Trust had an accrued pension liability of
$39,720, which is included in accrued expenses in the Statement of Assets and
Liabilities.


4. PREFERRED SHARES OF BENEFICIAL INTEREST

The Trust is authorized to issue up to 1,000,000 non-participating preferred
shares of beneficial interest having a par value of $.01 per share, in one or
more series, with rights as determined by the Trustees, without approval of the
common shareholders. The Trust has issued Series 1 through 5 Auction Rate
Preferred Shares ("Preferred Shares") which have a liquidation value of $50,000
per share plus the redemption premium, if any, plus accumulated but unpaid
dividends, whether or not declared, thereon to


                                       17


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
NOTES TO FINANCIAL STATEMENTS October 31, 2000, continued

the date of distribution. The Trust may redeem such shares, in whole or in
part, at the original purchase price of $50,000 per share plus accumulated but
unpaid dividends, whether or not declared, thereon to the date of redemption.

Dividends, which are cumulative, are reset through auction procedures.



<TABLE>
<CAPTION>
                         AMOUNT IN                    RESET          RANGE OF
 SERIES     SHARES*     THOUSANDS*       RATE*        DATE       DIVIDEND RATES**
--------   ---------   ------------   ----------   ----------   -----------------
<S>        <C>         <C>            <C>          <C>          <C>
   1           400        $20,000         4.05%    11/06/00     3.00% - 5.30%
   2           900         45,000         4.32     09/10/01     3.85  - 4.32
   3         1,000         50,000         4.45     07/09/01     3.60  - 4.45
   4           400         20,000         3.70     11/06/00     3.30  - 5.30
   5           400         20,000         4.13     11/06/00     3.35  - 5.30
</TABLE>

------------
 * As of October 31, 2000.
** For the year ended October 31, 2000.


Subsequent to October 31, 2000 and up through December 4, 2000, the Trust paid
dividends to each of the Series 1 through 5 at rates ranging from 3.70% to
4.45% in the aggregate amount of $922,980.

The Trust is subject to certain restrictions relating to the preferred shares.
Failure to comply with these restrictions could preclude the Trust from
declaring any distributions to common shareholders or purchasing common shares
and/or could trigger the mandatory redemption of preferred shares at
liquidation value.

The preferred shares, which are entitled to one vote per share, generally vote
with the common shares but vote separately as a class to elect two Trustees and
on any matters affecting the rights of the preferred shares.


5. COMMON SHARES OF BENEFICIAL INTEREST

Transactions in common shares of beneficial interest were as follows:

<TABLE>
<CAPTION>
                                                                                                                 CAPITAL
                                                                                                                 PAID IN
                                                                                                                EXCESS OF
                                                                                SHARES         PAR VALUE        PAR VALUE
                                                                            --------------   -------------   ---------------
<S>                                                                         <C>              <C>             <C>
Balance, October 31, 1998 ...............................................     28,433,013       $284,330       $ 407,956,085
Treasury shares purchased and retired (weighted average discount 5.33%)*        (368,900)        (3,689)         (4,989,590)
                                                                              ----------       --------       -------------
Balance, October 31, 1999 ...............................................     28,064,113        280,641         402,966,495
Treasury shares purchased and retired (weighted average discount 7.07%)*        (872,400)        (8,724)        (11,178,600)
                                                                              ----------       --------       -------------
Balance, October 31, 2000 ...............................................     27,191,713       $271,917       $ 391,787,895
                                                                              ==========       ========       =============
</TABLE>

------------
 * The Trustees have voted to retire the shares purchased.

                                       18


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
NOTES TO FINANCIAL STATEMENTS October 31, 2000, continued

6. FEDERAL INCOME TAX STATUS

During the year ended October 31, 2000 the Trust utilized approximately
$954,000 of its net capital loss carryover. At October 31, 2000, the Trust had
a net capital loss carryover of approximately $8,963,000 which may be used to
offset future capital gains to the extent provided by regulations, which is
available through October 31 of the following years:




<TABLE>
<CAPTION>
       AMOUNT IN THOUSANDS
---------------------------------
    2002         2003       2004
-----------   ---------   -------
<S>           <C>         <C>
$  3,930      $4,412      $621
=========     ======      ====
</TABLE>

7. DIVIDENDS TO COMMON SHAREHOLDERS

On September 26, 2000, the Trust declared the following dividends from net
investment income:



<TABLE>
<CAPTION>
    AMOUNT           RECORD               PAYABLE
  PER SHARE           DATE                  DATE
------------- -------------------   -------------------
<S>           <C>                   <C>
$  0.065      November 3, 2000      November 17, 2000
$  0.065      December 8, 2000      December 22, 2000
</TABLE>

8. EXPENSE OFFSET

The expense offset represents a reduction of the custodian fees for earnings on
cash balances maintained by the Trust.


9. RISKS RELATING TO CERTAIN FINANCIAL INSTRUMENTS

The Trust may invest a portion of its assets in residual interest bonds, which
are inverse floating rate municipal obligations. The prices of these securities
are subject to greater market fluctuations during periods of changing
prevailing interest rates than are comparable fixed rate obligations.

At October 31, 2000, the Trust held positions in residual interest bonds having
a total value of $25,571,250, which represents 4.7% of the Trust's net assets.


                                       19


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
FINANCIAL HIGHLIGHTS

Selected ratios and per share data for a common share of beneficial interest
outstanding throughout each period:



<TABLE>
<CAPTION>
                                                             FOR THE YEAR ENDED OCTOBER
                                                                         31*
                                                             ---------------------------
                                                                  2000          1999
                                                             ------------- -------------
<S>                                                          <C>           <C>
SELECTED PER SHARE DATA:
Net asset value, beginning of period .......................   $ 13.69         $ 15.47
                                                               -------        --------
Income (loss) from investment operations:
 Net investment income .....................................      1.01            1.01
 Net realized and unrealized gain (loss) ...................      0.79           (1.77)
                                                               -------        --------
Total income (loss) from investment operations .............      1.80           (0.76)
                                                               -------        --------
Less dividends from:
 Net investment income .....................................     (0.86)          (0.84)
 Common share equivalent of dividends paid to preferred
  shareholders .............................................     (0.22)          (0.19)
                                                               --------       --------
Total dividends ............................................     (1.08)          (1.03)
                                                               --------       --------
Anti-dilutive effect of acquiring treasury shares ..........      0.03            0.01
                                                               --------       --------
Net asset value, end of period .............................   $ 14.44         $ 13.69
                                                               ========       ========
Market value, end of period ................................   $ 12.813        $ 13.25
                                                               ========       ========
TOTAL RETURN+ ..............................................       3.29 %       (5.17)%
RATIOS TO AVERAGE NET ASSETS OF COMMON SHAREHOLDERS :
Total expenses .............................................       0.73 %        0.70 %
Net investment income before preferred stock dividends .....       7.27 %        6.71 %
Preferred stock dividends ..................................       1.59 %        1.26 %
Net investment income available to common shareholders .....       5.68 %        5.45 %
SUPPLEMENTAL DATA :
Net assets, end of period, in thousands ....................   $547,513      $539,277
Asset coverage on preferred shares at end of period ........        352%          347 %
Portfolio turnover rate ....................................         11%            5 %



<CAPTION>
                                                                       FOR THE YEAR ENDED OCTOBER 31*
                                                             --------------------------------------------------
                                                                  1998           1997               1996
                                                             ------------- ---------------- -------------------
<S>                                                          <C>           <C>              <C>
SELECTED PER SHARE DATA:
Net asset value, beginning of period .......................   $ 14.69        $   13.86        $    13.69
                                                               -------        ---------        ----------
Income (loss) from investment operations:
 Net investment income .....................................      1.00             1.00              0.97
 Net realized and unrealized gain (loss) ...................      0.71             0.70             (0.01)
                                                               -------        ---------        -----------
Total income (loss) from investment operations .............      1.71             1.70              0.96
                                                               -------        ---------        -----------
Less dividends from:
 Net investment income .....................................     (0.78)           (0.78)            (0.75)
 Common share equivalent of dividends paid to preferred
  shareholders .............................................     (0.20)           (0.19)            (0.17)
                                                               --------       ---------        -----------
Total dividends ............................................     (0.98)           (0.97)            (0.92)
                                                               --------       ---------        -----------
Anti-dilutive effect of acquiring treasury shares ..........      0.05             0.10              0.13
                                                               --------       ---------        -----------
Net asset value, end of period .............................   $ 15.47        $   14.69        $    13.86
                                                               ========       =========        ===========
Market value, end of period ................................   $14.813        $   13.25        $   11.625
                                                               ========       =========        ===========
TOTAL RETURN+ ..............................................     18.27%           21.21%             7.81%
RATIOS TO AVERAGE NET ASSETS OF COMMON SHAREHOLDERS:
Total expenses .............................................      0.69%            0.68%(1)          0.68%(1)
Net investment income before preferred stock dividends .....      6.60%            7.04%             7.06%
Preferred stock dividends ..................................      1.30%            1.31%             1.25%
Net investment income available to common shareholders .....      5.30%            5.73%             5.81%
SUPPLEMENTAL DATA :
Net assets, end of period, in thousands ....................  $594,807        $ 589,728        $  591,016
Asset coverage on preferred shares at end of period ........       383%             380%              381%
Portfolio turnover rate ....................................         7%               2%                1%
</TABLE>



-------------
*   The per share amounts were computed using an average number of shares
    outstanding during the period.
+   Total return is based upon the current market value on the last day of each
    period reported. Dividends are assumed to be reinvested at the prices
    obtained under the Trust's dividend reinvestment plan. Total return does not
    reflect brokerage commissions.
(1) Does not reflect the effect of expense offset of 0.01%.


                        See Notes to Financial Statements

                                       20


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
INDEPENDENT AUDITORS' REPORT

TO THE SHAREHOLDERS AND BOARD OF TRUSTEES
OF MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST:

We have audited the accompanying statement of assets and liabilities of Morgan
Stanley Dean Witter Insured Municipal Income Trust (the "Trust"), including the
portfolio of investments, as of October 31, 2000, and the related statements of
operations and changes in net assets, and financial highlights for the year
then ended. These financial statements and financial highlights are the
responsibility of the Trust's management. Our responsibility is to express an
opinion on these financial statements and financial highlights based on our
audit. The statement of changes in net assets for the year ended October 31,
1999 and the financial highlights for each of the respective stated periods
ended October 31, 1999 were audited by other independent accountants whose
report, dated December 8, 1999, expressed an unqualified opinion on that
statement and financial highlights.

We conducted our audit in accordance with auditing standards generally accepted
in the United States of America. Those standards require that we plan and
perform the audit to obtain reasonable assurance about whether the financial
statements and financial highlights are free of material misstatement. An audit
includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements. Our procedures included confirmation
of securities owned as of October 31, 2000, by correspondence with the
custodian. An audit also includes assessing the accounting principles used and
significant estimates made by management, as well as evaluating the overall
financial presentation. We believe that our audit provides a reasonable basis
for our opinion.

In our opinion, such financial statements and financial highlights referred to
above present fairly, in all material respects, the financial position of
Morgan Stanley Dean Witter Insured Municipal Income Trust as of October 31,
2000, the results of its operations, the changes in its net assets and the
financial highlights for the year then ended, in conformity with accounting
principles generally accepted in the United States of America.


Deloitte & Touche LLP
New York, New York
December 8, 2000
                      2000 FEDERAL TAX NOTICE (unaudited)

      For the year ended October 31, 2000, all of the Trust's dividends from
      net investment income received by both common and preferred shareholder
      classes were exempt interest dividends, excludable from gross income for
      Federal income tax purposes.


                                       21


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
CHANGE IN INDEPENDENT ACCOUNTANTS




On July 1, 2000 PricewaterhouseCoopers LLP resigned as independent accountants
of the Trust.

The reports of PricewaterhouseCoopers LLP on the financial statements of the
Trust for the past two fiscal years contained no adverse opinion or disclaimer
of opinion and were not qualified or modified as to uncertainty, audit scope or
accounting principle.

In connection with its audits for the two most recent fiscal years and through
July 1, 2000, there have been no disagreements with PricewaterhouseCoopers LLP
on any matter of accounting principles or practices, financial statement
disclosure, or auditing scope or procedure, which disagreements if not resolved
to the satisfaction of PricewaterhouseCoopers LLP would have caused them to
make reference thereto in their report on the financial statements for such
years.

The Trust, with the approval of its Board of Trustees and its Audit Committee,
engaged Deloitte & Touche LLP as its new independent auditors as of July 1,
2000.


                                       22


<PAGE>

MORGAN STANLEY DEAN WITTER INSURED MUNICIPAL INCOME TRUST
REVISED INVESTMENT POLICY

On January 26, 2000, the Trustees of Morgan Stanley Dean Witter Insured
Municipal Income Trust (the "Trust") approved an investment policy whereby the
Trust would be permitted to invest up to 10% of its assets in inverse floating
rate municipal obligations. The inverse floating rate municipal obligations in
which the Trust will invest are typically created through a division of a fixed
rate municipal obligation into two separate instruments, a short-term
obligation and a long-term obligation. The interest rate on the short-term
obligation is set at periodic auctions. The interest rate on the long-term
obligation is the rate the issuer would have paid on the fixed income
obligation: (i) plus the difference between such fixed rate and the rate on the
short-term obligation, if the short-term rate is lower than the fixed rate; or
(ii) minus such difference if the interest rate on the short-term obligation is
higher than the fixed rate. The interest rates on these obligations generally
move in the reverse direction of market interest rates. If market interest
rates fall, the interest rate on the obligation will increase and if market
interest rates increase, the interest rate on the obligation will fall. Inverse
floating rate municipal obligations offer the potential for higher income than
is available from fixed rate obligations of comparable maturity and credit
rating. They also carry greater risks. In particular, the prices of inverse
floating rate municipal obligations are more volatile, i.e., they increase and
decrease in response to changes in interest rates to a greater extent than
comparable fixed rate obligations.


                                       23




<PAGE>

                                                                  MORGAN STANLEY
                                                                  DEAN WITTER
                                                                  INSURED
                                                                  MUNICIPAL
                                                                  INCOME TRUST




TRUSTEES
---------------------------------------------------
Michael Bozic
Charles A. Fiumefreddo
Edwin J. Garn
Wayne E. Hedien
James F. Higgins
Dr. Manuel H. Johnson
Michael E. Nugent
Philip J. Purcell
John L. Schroeder

OFFICERS
---------------------------------------------------
Charles A. Fiumefreddo
Chairman and Chief Executive Officer

Mitchel M. Merin
President

Barry Fink
Vice President, Secretary and General Counsel

James F. Willison
Vice President

Thomas F. Caloia
Treasurer

TRANSFER AGENT
---------------------------------------------------
Morgan Stanley Dean Witter Trust FSB
Harborside Financial Center-Plaza Two
Jersey City, New Jersey 07311

INDEPENDENT AUDITORS
---------------------------------------------------
Deloitte & Touch LLP
Two World Financial Center
New York, New York 10281

INVESTMENT MANAGER
---------------------------------------------------
Morgan Stanley Dean Witter Advisors Inc.
Two World Trade Center
New York, New York 10048


                                                                Annual Report
                                                                October 31, 2000


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