EXPRESS SCRIPTS INC
S-8, 1998-12-29
SPECIALTY OUTPATIENT FACILITIES, NEC
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            As filed with the Securities and Exchange Commission on
                 December 29, 1998 Registration No. 333-_____


                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933


                              EXPRESS SCRIPTS, INC.
             (Exact name of registrant as specified in its charter)

          DELAWARE                                    43-1420563
(State or other jurisdiction of          (I.R.S. Employer Identification No.)
 incorporation or organization)


                              14000 RIVERPORT DRIVE
                        MARYLAND HEIGHTS, MISSOURI 63043
          (Address, including zip code, of principal executive offices)

               EXPRESS SCRIPTS, INC. EMPLOYEE STOCK PURCHASE PLAN
                            (Full title of the plan)

                            THOMAS M. BOUDREAU, ESQ.
     SENIOR VICE PRESIDENT OF ADMINISTRATION, GENERAL COUNSEL AND SECRETARY
                              EXPRESS SCRIPTS, INC.
             14000 RIVERPORT DRIVE, MARYLAND HEIGHTS, MISSOURI 63043
                                 (314) 770-1666
                      (Name, address and telephone number,
                   including area code, of agent for service)

                         CALCULATION OF REGISTRATION FEE
- -------------------------------------------------------------------------------
                                      Proposed        Proposed
    Title of                           maximum        maximum
   securities           Amount        offering       aggregate       Amount of
     to be              to be           price         offering     registration
   registered         registered     per share(1)     price(1)         fee(1)
- --------------------------------------------------------------------------------
Class A Common
Stock, par value
$0.01 per share    250,000 shares(2)   $66.75        $16,687,500     $4,922.81
- --------------------------------------------------------------------------------

     (1) Estimated  solely for the purpose of calculating the  registration  fee
pursuant to Rule 457(c) and (h) under the  Securities Act of 1933 and based upon
the average of the high and low reported market prices of the Registrant's Class
A Common Stock on December 28, 1998. 

     (2) This Registration Statement also covers such additional shares of Class
A Common Stock as may be issuable  pursuant to  antidilution  provisions  of the
Express Scripts, Inc. Employee Stock Purchase Plan.

<PAGE>

                                     PART II
               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF DOCUMENTS BY REFERENCE.

     Express  Scripts,   Inc.  (the  "Company"  or  the   "registrant")   hereby
incorporates  by  reference  into  this  Registration  Statement  the  following
documents of the registrant:

         (a) Annual Report on Form 10-K for the year ended December 31, 1997.

         (b) Quarterly Reports on Form 10-Q for the quarters ended March 31,
1998, June 30, 1998 and September 30, 1998.

         (c) Current Report on Form 8-K dated February 19, 1998, and filed March
2, 1998; Current Report on Form 8-K dated February 23, 1998, and filed February
24, 1998; and Current Report on Form 8-K dated March 16, and filed March 26,
1998; Current Report on Form 8-K dated April 1, 1998, and filed April 14, 1998,
as amended on Form 8-K/A filed June 12, 1998; Current Report on Form 8-K, dated
April 23, 1998 and filed May 5, 1998; Current Report on Form 8-K, dated June 17,
1998, and filed July 20, 1998; Current Report on Form 8-K, dated July 28, 1998,
and filed August 5, 1998; Current Report on Form 8-K, dated October 12, 1998,
and filed October 27, 1998; Current Report on Form 8-K, dated October 21, 1998,
and filed October 29, 1998; and Current Report on Form 8-K, dated November 1,
1998, and filed November 20, 1998.

         (d) The description of the Class A Common Stock as contained in Item 1
of the Company's Registration Statement on Form 8-A filed May 12, 1992,
including any amendment or report filed for the purpose of updating such
description.

     All documents subsequently filed by the Company pursuant to Sections 13(a),
13(c),  14 and 15(d) of the  Securities  Exchange  Act of 1934,  as amended (the
"Exchange  Act"),  prior  to the  filing  of a  post-effective  amendment  which
indicates  that  all  securities  offered  hereunder  have  been  sold or  which
deregisters  all  securities  then  remaining  unsold,  shall  be  deemed  to be
incorporated by reference in this Registration Statement and to be a part hereof
from the date of filing of such documents.

     Any  statement  contained  in a  document  incorporated  or  deemed  to  be
incorporated  herein by reference  shall be deemed to be modified or  superseded
for  purposes  of this  Registration  Statement  to the extent  that a statement
contained herein or in any other subsequently filed document which also is or is
deemed to be  incorporated  herein by  reference  modifies  or  supersedes  such
statement.

ITEM 4.  DESCRIPTION OF SECURITIES.

         Not applicable.

ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.

     Thomas M. Boudreau, Esq., whose opinion is contained in Exhibit 5.1, owned,
as of December 21, 1998,  options to purchase  113,500  shares of Class A Common
Stock.

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

     Section  102(b)(7) of the General  Corporation Law of Delaware (the "DGCL")
enables  a  corporation  in its  original  certificate  of  incorporation  or an
amendment thereto to eliminate or limit the personal  liability of a director to
a corporation or its  stockholders  for  violations of the director's  fiduciary
duty,  except  (i)  for any  breach  of a  director's  duty  of  loyalty  to the
corporation or its stockholders, (ii) for acts or omissions not in good faith or
which  involve  intentional  misconduct  or a knowing  violation  of law,  (iii)
pursuant to Section 174 of the DGCL  (providing  for  liability of directors for
unlawful  payment of dividends or unlawful stock  purchases or  redemptions)  or
(iv) for any  transaction  from which a director  derived an  improper  personal
benefit.  Article Eight of the Company's  Certificate of Incorporation  provides
that no  director  shall  have any  personal  liability  to the  Company  or its
stockholders  for  any  monetary  damages  for  breach  of  fiduciary  duty as a
director, provided that such provision does not limit or eliminate the liability
of any director (i) for breach of such director's duty of loyalty to the Company
or its  stockholders,  (ii) for  acts or  omissions  not in good  faith or which
involve intentional  misconduct or knowing violation of law, (iii) under Section
174 of the DGCL (involving  certain unlawful  dividends or stock repurchases) or
(iv) for any transaction from which such director  derived an improper  personal
benefit.

     Section 145 of the DGCL provides,  in summary,  that directors and officers
of Delaware  corporations  are  entitled,  under  certain  circumstances,  to be
indemnified  against all expenses and liabilities  (including  attorneys'  fees)
incurred by them as a result of suits brought  against them in their capacity as
a  director  or  officer,  if they  acted in good  faith  and in a  manner  they
reasonably  believed  to be in or not  opposed  to  the  best  interests  of the
corporation, and, with respect to any criminal action or proceeding, if they had
no reasonable  cause to believe their  conduct was unlawful;  provided,  that no
indemnification  may be made against expenses in respect of any claim,  issue or
matter  as to  which  they  shall  have  been  adjudged  to  be  liable  to  the
corporation,  unless and only to the extent  that the court in which such action
or  suit  was  brought  shall  determine  upon  application  that,  despite  the
adjudication of liability but in view of all the circumstances of the case, they
are fairly and  reasonably  entitled to indemnity  for such  expenses  which the
court shall deem proper. Any such indemnification may be made by the corporation
only  as  authorized  in  each  specific  case  upon  a  determination   by  the
stockholders or disinterested  directors that  indemnification is proper because
the indemnitee has met the applicable standard of conduct.  Article Seven of the
Company's  Certificate of Incorporation  entitles  officers and directors of the
Company to indemnification to the fullest extent permitted by Section 145 of the
DGCL, as amended from time to time.

     New York Life Insurance  Company ("New York Life") maintains  Directors and
Officers/Corporate   Reimbursement  ("D&O")  insurance  covering  directors  and
officers  of New York Life and its  subsidiaries,  including  the  Company,  and
certain other  entities for certain  expenses and  liabilities of such directors
and officers  while acting in their  capacity as such.  Such D&O insurance  also
covers  directors and officers of the Company  while New York Life,  directly or
indirectly, maintains voting control of the Company.

     Insofar as indemnification for liabilities arising under the Securities Act
of 1933 may be  permitted  to  directors,  officers or persons  controlling  the
Company pursuant to such  provisions,  the Company has been informed that in the
opinion of the  Securities  and  Exchange  Commission  such  indemnification  is
against public policy as expressed in such Act and is therefore unenforceable.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED.

         Not applicable.

ITEM 8.  EXHIBITS.

         Reference is made to the Exhibit Index.

ITEM 9.  UNDERTAKINGS.

     (a) The undersigned registrant hereby undertakes:

     (1) To file,  during any period in which  offers or sales are being made, a
post-effective amendment to this registration statement:

     (i)  To  include  any  prospectus  required  by  Section  10(a)(3)  of  the
Securities Act of 1933;

     (ii) To reflect in the  prospectus  any facts or events  arising  after the
effective date of this Registration Statement (or the most recent post-effective
amendment  hereof)  which,  individually  or  in  the  aggregate,   represent  a
fundamental change in the information set forth in this Registration  Statement.
Notwithstanding the foregoing,  any increase or decrease in volume of securities
offered (if the total dollar value of  securities  offered would not exceed that
which  was  registered)  and any  deviation  from  the  low or  high  end of the
estimated  maximum  offering  range may be reflected  in the form of  prospectus
filed with the  Commission  pursuant to Rule 424(b) of the Securities Act if, in
the  aggregate,  the  changes in volume and price  represent  no more than a 20%
change in the maximum aggregate  offering price set forth in the "Calculation of
Registration Fee" table in the effective registration statement; and

     (iii) To  include  any  material  information  with  respect to the plan of
distribution  not  previously  disclosed  in the  Registration  Statement or any
material change to such information in the Registration Statement;

     PROVIDED, HOWEVER, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if
the information  required to be included in a post-effective  amendment by those
paragraphs is contained in periodic reports filed by the registrant  pursuant to
Section  13 or Section  15(d) of the  Securities  Exchange  Act of 1934 that are
incorporated by reference in the Registration Statement.

     (2) That, for the purpose of determining any liability under the Securities
Act of 1933,  each  such  post-effective  amendment  shall be deemed to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities at that time shall be deemed to be the initial BONA
FIDE offering thereof.

     (3) To remove from registration by means of a post-effective  amendment any
of the securities being registered which remain unsold at the termination of the
offering.

     (b) The  undersigned  registrant  hereby  undertakes  that, for purposes of
determining  any liability  under the Securities Act of 1933, each filing of the
registrant's  annual report pursuant to Section 13(a) or 15(d) of the Securities
Exchange Act of 1934 (and, where applicable,  each filing of an employee benefit
plan's annual report pursuant to Section 15(d) of the Securities Exchange Act of
1934) that is incorporated by reference in the  registration  statement shall be
deemed to be a new  registration  statement  relating to the securities  offered
therein,  and the offering of such securities at that time shall be deemed to be
the initial BONA FIDE offering thereof.

     (c) Insofar as indemnification for liabilities arising under the Securities
Act of 1933 may be permitted to directors,  officers and controlling  persons of
the  registrant  pursuant  to  the  foregoing  provisions,   or  otherwise,  the
registrant  has been advised that in the opinion of the  Securities and Exchange
Commission such indemnification is against public policy as expressed in the Act
and is, therefore,  unenforceable. In the event that a claim for indemnification
against such  liabilities  (other than the payment by the registrant of expenses
incurred or paid by a director,  officer or controlling person of the registrant
in the successful  defense of any action,  suit or proceeding) is being asserted
by  such  director,  officer  or  controlling  person  in  connection  with  the
securities being  registered,  the registrant will, unless in the opinion of its
counsel the matter has been settled by controlling precedent,  submit to a court
of appropriate  jurisdiction the question of whether such  indemnification by it
is against  public  policy as  expressed  in the Act and will be governed by the
final adjudication of such issue.

<PAGE>

                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the undersigned
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration
statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of Maryland Heights, State of Missouri, on December 11,
1998.

                                    EXPRESS SCRIPTS, INC.


                                    By:  /s/ Barrett A. Toan
                                         Barrett A. Toan, President
                                         and Chief Executive Officer


                                POWER OF ATTORNEY

     Each person whose signature  appears below hereby  constitutes and appoints
Barrett A. Toan,  George Paz and Thomas M.  Boudreau and each of them (with full
power to each of them to act  alone),  his or her true and lawful  attorneys  in
fact and  agents for him or her and on his or her behalf and in his or her name,
place  and  stead,  in any and all  capacities  to sign  any and all  amendments
(including  post-effective  amendments) to this Registration  Statement,  and to
file the same,  with exhibits and any and all other documents filed with respect
thereto,  with the Securities and Exchange Commission (or any other governmental
or regulatory authority),  granting unto said attorneys,  and each of them, full
power and authority to do and to perform each and every act and thing  requisite
and  necessary to be done in and about the premises in order to  effectuate  the
same as fully to all  intents  and  purposes  as he or she  might or could do if
personally  present,  hereby ratifying and confirming all that said attorneys in
fact and agents,  or any of them,  may lawfully do or cause to be done by virtue
hereof.


     Pursuant  to  the   requirements  of  the  Securities  Act  of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the dates indicated.

       NAME                             TITLE                       DATE


/S/  BARRETT A. TOAN       President, Chief Executive         December 11, 1998
   Barrett A. Toan         Officer and Director

/S/ GEORGE PAZ             Senior Vice President and Chief    December 11, 1998
  George Paz               Financial Officer (Principal
                           Financial Officer)

/S/ JOSEPH W. PLUM         Vice President and Chief           December 11, 1998
  Joseph W. Plum           Accounting Officer (Principal
                           Accounting Officer)

/S/ HOWARD I. ATKINS       Director                           December 16, 1998
  Howard I. Atkins

/S/ JUDITH E. CAMPBELL     Director                           December 15, 1998
  Judith E. Campbell

/S/ RICHARD M. KERNAN, JR. Director                           December 15, 1998
  Richard M. Kernan, Jr.

/S/ RICHARD A. NORLING     Director                           December 14, 1998
  Richard A. Norling

/S/ FREDERICK J. SIEVERT   Director                           December 16, 1998
  Frederick J. Sievert

/S/ STEPHEN N. STEINIG     Director                           December 16, 1998
  Stephen N. Steinig

/S/ SEYMOUR STERNBERG      Director                           December 16, 1998
  Seymour Sternberg

/S/ HOWARD L. WALTMAN      Director                           December 16, 1998
  Howard L. Waltman

/S/ Norman Zachary         Director                           December 21, 1998
  Norman Zachary


<PAGE>
                              EXPRESS SCRIPTS, INC.


                                  EXHIBIT INDEX
Exhibit
NUMBER                             DESCRIPTION

   4.1      Express Scripts, Inc. Employee Stock Purchase Plan

   5.1      Opinion of Thomas M.  Boudreau,  Esq.,  Senior Vice  President of
            Administration, General Counsel and Secretary of the Company

  23.1      Consent of PricewaterhouseCoopers LLP

  23.2      Consent of Ernst & Young LLP - Minneapolis, Minnesota

  23.3      Consent of Ernst & Young LLP - Pittsburgh, Pennsylvania

  23.4      Consent of Thomas M. Boudreau, Esq. (included in Exhibit 5.1)

  24.1      Power of Attorney (included in Signature Page)



                                   Exhibit 4.1

                              EXPRESS SCRIPTS, INC.
                          EMPLOYEE STOCK PURCHASE PLAN

     1. PURPOSE.  The purpose of the Plan is to provide employees of the Company
and its Designated  Subsidiaries with an opportunity to purchase Common Stock of
the Company through accumulated  payroll deductions.  It is the intention of the
Company to have the Plan  qualify as an  "Employee  Stock  Purchase  Plan" under
Section 423 of the Internal Revenue Code of 1986, as amended.  The provisions of
the  Plan  shall,   accordingly,   be  construed  so  as  to  extend  and  limit
participation in a manner consistent with the requirement of that section of the
Code.

     2. DEFINITIONS.

     a) "Board" shall mean the Board of Directors of the Company.

     b) "Code" shall mean the Internal Revenue Code of 1986, as amended.

     c) "Common Stock" shall mean the Class A Common Stock,  par value $0.01, of
the Company.

     d) "Company" shall mean Express Scripts, Inc., a Delaware corporation, and,
unless the context requires otherwise, any Designated Subsidiary.

     e)  "Compensation"  shall mean all regular straight time gross earnings and
commissions,  exclusive  of payments  for  overtime,  shift  premium,  incentive
payments,   bonuses  and  other   compensation,   and  without   reduction   for
contributions to any 401(k) plan sponsored by the Company.

     f)  "Contributions"  shall mean all  amounts  credited  to the account of a
participant pursuant to the Plan.

     g)  "Designated  Subsidiary"  shall  mean  any  Subsidiary  which  has been
designated by the Board from time to time in its sole  discretion as eligible to
participate in the Plan.

     h)  "Employee"  shall mean any person who is an employee of the Company for
tax purposes whose customary employment with the Company is at least twenty (20)
hours per week and more than five (5) months in a calendar year. For purposes of
the Plan,  the  employment  relationship  shall be treated as continuing  intact
while the  individual  is on short  term  disability  or other  leave of absence
approved  by the  Company.  Where the  period of leave  exceeds  90 days and the
individual's  right to  reemployment  is not guaranteed  either by statute or by
contract, the employment  relationship shall be deemed to have terminated on the
91st day of such leave.

     i)  "Exchange  Act"  shall mean the  Securities  Exchange  Act of 1934,  as
amended.

     j)  "Offering  Date"  shall mean the first  business  day of each  Offering
Period of the Plan.

     k) "Offering  Period"  shall mean a period of six (6) months  commencing on
March 1 and September 1 of each year  (commencing  with March 1, 1999) except as
otherwise indicated by the Company.

     l) "Plan" shall mean this Employee Stock Purchase Plan.

     m) "Purchase  Date" shall mean the last day of each Offering  Period of the
Plan.

     n) "Subsidiary"  shall mean a corporation,  domestic or foreign,  which not
less than 50% of the  voting  shares are held by the  Company  or a  Subsidiary,
whether or not such corporation now exists or is hereafter organized or acquired
by the Company or a Subsidiary.

     3. ELIGIBILITY.

     a) Any person who is an Employee of the Company as of the Offering  Date of
a given  Offering  Period,  who has  continuously  been an Employee for at least
three months, and who is not a "senior  executive" of the Company,  as such term
may be defined  from time to time by the Board (or any  committee  administering
the Plan in accordance with Section 13 hereof), shall be eligible to participate
in such Offering Period under the Plan,  subject to the  requirements of Section
5(a) and the limitations imposed by Section 423(b) of the Code.

     b) Any provisions of the Plan to the contrary notwithstanding,  no Employee
shall be granted an option under the Plan (i) if,  immediately  after the grant,
such  Employee (or any other person whose stock would be  attributed  to such an
Employee  pursuant to Section  424(d) of the  Code)would  own stock  and/or hold
outstanding options to purchase stock possessing five percent (5%)or more of the
total  combined  voting power or value of all classes of stock of the Company or
of any  Subsidiary,  or (ii) if such  option  would  permit his or her rights to
purchase stock under all employee stock purchase plans (described in Section 423
of the Code) of the  Company  and its  Subsidiaries  to  accrue at a rate  which
exceeds twenty-five thousand dollars ($25,000)of fair market value of such stock
(determined  at the time such option is granted) for each calendar year in which
such option is outstanding at any time.

     4. OFFERING PERIODS.  The Plan shall be implemented by a series of Offering
Periods of six (6) months duration,  with new Offering Periods  commencing on or
about  March 1 and  September  1 of each year (or at such other time or times as
may be  determined by the Board of  Directors).  The Plan shall  continue  until
terminated in accordance with Section 19 hereof.  The Board shall have the power
to change the duration  and/or the frequency of the Offering Period with respect
to future offerings without stockholder  approval if such change is announced at
least fifteen (15) days prior to the scheduled  beginning of the first  Offering
Period to be affected.

     5. PARTICIPATION.

     a) An eligible  Employee may become a participant in the Plan by completing
a  subscription  agreement  (in such form and manner as may be  approved  by the
Board or the committee  administering the Plan) authorizing  payroll  deductions
and filing it with the Company's  payroll office at least five (5) business days
prior to the applicable Offering Date. A subscription  agreement in effect for a
participant  for a  particular  Offering  Period  will  continue  in effect  for
subsequent  Offering Periods if the participant remains an eligible Employee and
has not withdrawn the subscription agreement pursuant to Section 10.

     b) Payroll  deductions  shall  commence on the first payroll  following the
Offering  Date and shall end on the last payroll paid in the Offering  Period to
which the subscription agreement is applicable,  unless sooner terminated by the
participant as provided in Section 10 hereof.

     c) By  enrolling  in the  Plan,  each  participant  will be  deemed to have
authorized  the  establishment  of a  brokerage  account in his or her name at a
securities  brokerage  firm,  which firm shall serve as custodial  agent for the
purpose of holding shares purchased under the Plan. The account will be governed
by, and subject to, the terms and  conditions  of a written  agreement  with the
firm  approved  by the Board or the  committee  administering  the  Plan,  which
agreement  shall,  among other  things,  reflect the  restrictions  contained in
Section 21(c) and Section 21(d).

     d) Subject to the limitations of Section 3 hereof and Section  423(b)(8) of
the Code,  all cash  dividends,  if any,  paid with  respect to shares of Common
Stock purchased under the Plan and held in a participant's  account  established
under  Section  5(c) shall be  automatically  invested in shares of Common Stock
purchased  at One Hundred  Percent  (100%) of fair market  value (as  determined
under Section 7(b)) on the next Purchase  Date.  All non-cash  distributions  on
Common  Stock  purchased  under  the Plan and  held in a  participant's  account
established  under  Section  5(c)  shall be paid to the  participant  as soon as
practical.

     6. METHOD OF PAYMENT OF CONTRIBUTIONS.

     a) The  participant  shall elect to have payroll  deductions  made each pay
period  during the  Offering  Period in an amount not less than one percent (1%)
and not more than ten percent (10%), in whole number percentage  increments,  of
such participant's  Compensation in each pay period. All payroll deductions made
by a  participant  shall be  credited to his or her  account  under the Plan.  A
participant  may not make any additional  payments into such account.  Except as
otherwise provided in this Section 6(a), all Employees granted options under the
Plan shall have the same rights and privileges.

     b) A participant may increase or decrease his or her payroll  deductions by
filing a new subscription  agreement at any time during an Offering Period.  The
change may not become  effective sooner than the next pay period after filing of
the subscription  agreement.  The Board or the committee administering the Plan,
at its discretion, may limit the number of participation rate changes during any
Offering Period and may, in its discretion, require up to five (5) business days
prior written notice.

     c) A participant may discontinue  his or her  participation  in the Plan as
provided in Section 10 hereof.

     d)  Notwithstanding  the foregoing,  to the extent necessary to comply with
Section  423(b)(8) of the Code and Section 6(a) hereof, a participant's  payroll
deductions may be decreased to zero percent (0%) at any time during the Offering
Period.  Payroll  deductions  shall  recommence  at the  rate  provided  in such
participant's  subscription  agreement at the  beginning  of the first  Offering
Period  which  is  scheduled  to end  in the  following  calendar  year,  unless
terminated by the participant as provided in Section 10 hereof.

     e) At the time of each exercise of a participant's  option, and at the time
any Common  Stock  issued  under the Plan to a  participant  is disposed of, the
participant must adequately  provide for the Company's  federal,  state or other
tax withholding obligations,  if any, that arise upon the exercise of the option
or the  disposition of the Common Stock.  At any time, the Company may, but will
not be obligated to,  withhold from the  participant's  compensation  the amount
necessary for the Company to meet applicable withholding obligations,  including
but not limited to, any  withholding  required to make  available to the Company
any tax deductions or benefits  attributable to the sale or early disposition of
Common Stock by the participant.

     7. GRANT OF OPTION.

     a) On the Offering Date of each  Offering  Period,  each eligible  Employee
participating in such Offering Period shall automatically be deemed to have been
granted an option to  purchase  on the  Purchase  Date a number of shares of the
Company's  Common Stock  determined  by dividing such  Employee's  Contributions
accumulated  prior to such  Purchase  Date  and  retained  in the  participant's
account as of the Purchase Date by eighty-five  percent  (85%)of the fair market
value of the Company's  Common Stock on the Purchase  Date;  provided,  however,
that in no event shall an Employee be permitted to purchase during each Offering
Period more than 1,000 shares (subject to any adjustment pursuant to Section 18)
and provided  further that such purchase shall be subject to the limitations set
forth in Section 3(b). The fair market value of the Company's Common Stock shall
be determined as provided in Section 7(b).

     b) The fair  market  value of the  Company's  Common  Stock on a given date
shall be equal to the closing sales price of Common Stock on the date  preceding
the date of determination  (or, in the event that the Common Stock is not traded
on such date,  on the  immediately  preceding  trading date on which there was a
closing sales price), as reported by The Nasdaq National Market or, in the event
the Common Stock is listed on a stock exchange,  the fair market value per share
shall be the closing sales price on such exchange on the date preceding the date
of  determination  (or, in the event that the Common Stock is not traded on such
date, on the immediately preceding trading date), as reported in THE WALL STREET
JOURNAL.  In the  absence  of any  listing  of the  Common  Stock on The  Nasdaq
National Market or on any established  stock exchange,  the fair market value of
the Common Stock on a given date shall be determined in good faith by the Board.

     8.  EXERCISE OF OPTION.  Unless a  participant  withdraws  from the Plan as
provided in Section 10 hereof, his or her option for the purchase of shares will
be exercised  automatically on the Purchase Date of the Offering Period, and the
maximum  whole number of shares  subject to such option will be purchased at the
applicable  option  price  with  the  accumulated  Contributions  in  his or her
account,  subject to the  limitations  in this Plan.  The shares  purchased upon
exercise  of an  option  hereunder  shall be held in the  participant's  account
established  under  Section 5(c)  pursuant to Section  21(c) and Section  21(d).
During his or her lifetime,  a participant's option to purchase shares hereunder
is exercisable only by him or her.

     9.  DELIVERY.  As promptly as  practicable  after the Purchase Date of each
Offering  Period,  the Company shall arrange the delivery by direct deposit into
the account  established  for each  participant  under Section 5(c),  the shares
purchased  upon exercise of his or her option.  Any cash remaining to the credit
of a  participant's  account  under the Plan after a  purchase  by him or her of
shares on the Purchase Date, other than amounts representing  fractional shares,
will be  returned  to him or her as soon as  practicable.  Amounts  representing
fractional shares will be carried forward for use in subsequent purchases.

     10. VOLUNTARY WITHDRAWAL; TERMINATION OF EMPLOYMENT.

     a) A participant may withdraw from an Offering Period all but not less than
all the Contributions  credited to his or her account under the Plan at any time
prior to [five (5)]  business  days prior to the  Purchase  Date of the Offering
Period  by  completing  a Company  approved  notice  of  withdrawal.  All of the
participant's  Contributions  credited to his or her account will be paid to him
or her as soon as  practicable  after receipt of his or her notice of withdrawal
and his or her option of the current  period will be  automatically  terminated,
and no further  Contributions for the purchase of shares will be made during the
Offering  Period.  Payroll  deductions  shall not resume at the beginning of the
succeeding Offering Period unless the participant  delivers to the Company a new
subscription agreement in accordance with this Plan.

     b) A  participant's  withdrawal  from an offering  will not have any effect
upon his or her eligibility to participate in a succeeding Offering Period or in
any similar plan which may hereafter be adopted by the Company.

     c) Upon a  participant's  ceasing to be an Employee  prior to the  Purchase
Date of an Offering Period for any reason,  including  retirement or death,  the
Contributions credited to his or her account and not yet applied to the purchase
of shares will be  returned to him or her,  or, in the case of his or her death,
to the person or  persons  entitled  thereto  under  Section  14, and his or her
option will be automatically  terminated,  provided that if the Company does not
learn of such death more than five (5) business days prior to the Purchase Date,
payroll deductions  credited to the participant's  account may be applied to the
purchase of shares under the Plan on such Purchase Date.

     d) In the event an  Employee's  salary  grade level is elevated or title or
position  is  changed  so as to make an  Employee  a "senior  executive"  of the
Company during the Offering Period in which the Employee is a participant, he or
she will be deemed to have elected to withdraw  from the Plan and  Contributions
credited  to his or her  account  will be  returned to him or her and his or her
option terminated.

     11.  INTEREST.   No  interest  shall  accrue  on  the  Contributions  of  a
participant in the Plan.

     12. STOCK.

     a) The maximum  number of shares of the Company's  Common Stock which shall
be made available for purchase under the Plan shall be 250,000  shares,  subject
to  adjustment  upon  changes in  capitalization  of the  Company as provided in
Section 18 hereof.  These shares may be newly issued or may be purchased for the
Plan on the open market or from private  sources.  If the total number of shares
which would otherwise be subject to options granted  pursuant to Section 7(a) on
the  Offering  Date of an  Offering  Period  exceeds  the number of shares  then
available  under the Plan (after  deduction of all shares for which options have
been  exercised  or are then  outstanding),  the  Company  shall make a pro rata
allocation  of the shares  remaining  available for option grant in as uniform a
manner as shall be  practicable  and as it shall  determine to be equitable.  In
such event,  the Company  shall give  written  notice of such  reduction  of the
number of shares  subject to the option to each  Employee  affected  thereby and
shall similarly reduce the rate of Contributions, if necessary.


     b) The participant  will have no interest or voting right in shares covered
by his or her option until such option has been exercised.

     c)  Shares  to be  delivered  to a  participant  under  the  Plan  will  be
registered in the name of the  participant  or in the "Street Name" of a Company
approved broker, subject to Section 21 hereof.

     13.  ADMINISTRATION.  The Board, or a committee  named by the Board,  shall
supervise and  administer the Plan and  --------------  shall have full power to
adopt,  amend and rescind any rules deemed  desirable  and  appropriate  for the
administration  of the Plan and not inconsistent  with the Plan, to construe and
interpret the Plan, and to make all other determinations  necessary or advisable
for the administration of the Plan. The composition of the committee shall be in
accordance  with the  requirements  to obtain or retain any available  exemption
from the  operation of Section  16(b) of the Exchange Act pursuant to Rule 16b-3
promulgated  thereunder.  To aid in the administration of the Plan, the Board or
the  committee  may  appoint a Plan  administrator  and  allocate  to it certain
limited  responsibilities  to  carry  out the  directives  of the  Board  or the
committee in all phases of the administration of the Plan.

     14. DESIGNATION OF BENEFICIARY.

     a) A participant may file a written  designation of a beneficiary who is to
receive shares and cash, if any, from the  participant's  account under the Plan
in the event of such  participant's  death  subsequent to the end of an Offering
Period but prior to delivery to him or her of such shares and cash. In addition,
a participant may file a written  designation of a beneficiary who is to receive
any cash  from the  participant's  account  under  the Plan in the event of such
participant's  death  prior to the  Purchase  Date of an Offering  Period.  If a
participant is married and the designated beneficiary is not the spouse, spousal
consent shall be required for such designation to be effective.

     b) Such  designation of beneficiary may be changed by the participant  (and
his or her spouse,  if any) at any time by written  notice.  In the event of the
death of a participant  and in the absence of a beneficiary  validly  designated
under  the  Plan who is  living  at the time of such  participant's  death,  the
Company shall  deliver such shares and/or cash to the executor or  administrator
of the estate of the participant,  or if no such executor or  administrator  has
been  appointed  (to  the  knowledge  of  the  Company),  the  Company,  in  its
discretion,  may deliver such shares  and/or cash to the spouse or to any one or
more dependents or relatives of the participant,  or if no spouse,  dependent or
relative is known to the  Company,  then to such other person as the Company may
designate.

     15.  TRANSFERABILITY.  Neither  Contributions  credited to a  participant's
account nor any rights  with  regard to the  exercise of an option or to receive
shares  under  the Plan  may be  assigned,  transferred,  pledged  or  otherwise
disposed  of  in  any  way  (other  than  by  will,  the  laws  of  descent  and
distribution,  or as provided in Section 14 hereof) by the participant. Any such
attempt at assignment,  transfer,  pledge or other  disposition shall be without
effect,  except that the Company may treat such act as election to withdraw  all
Contributions in accordance with Section 10 hereof.

     16. USE OF FUNDS. All  Contributions  received or held by the Company under
the Plan may be used by the Company for any corporate  purpose,  and the Company
shall not be obligated to segregate such Contributions.

     17. REPORTS. Individual accounts will be maintained for each participant in
the  Plan.  Statements  of  account  will be  given to  participating  Employees
promptly following the Purchase Date, which statements will set forth the amount
of Contributions,  the per share purchase price, the number of shares purchased,
the remaining cash balance, if any, and the dividends received,  if any, for the
period covered.

     18. ADJUSTMENTS UPON CHANGES IN CAPITALIZATION; CORPORATE TRANSACTIONS.

     a)  CHANGES  IN  CAPITALIZATION.  Subject  to any  required  action  by the
stockholders  of the Company,  the number of shares of Common  Stock  covered by
each option  under the Plan which has not yet been  exercised  and the number of
shares of Common Stock which have been  authorized  for issuance  under the Plan
but have not yet been placed under option  (collectively,  the  "Reserves"),  as
well as the price per share of Common  Stock  covered by each  option  under the
Plan which has not yet been exercised,  shall be appropriately  adjusted for any
changes in the Common Stock  resulting from a stock split,  reverse stock split,
stock  dividend,  combination or  reclassification  of the Common Stock,  or any
similar changes in the Company's  capitalization.  Such adjustment shall be made
by the Board or the committee  administering  this Plan, whose  determination in
that  respect  shall be final,  binding  and  conclusive.  Except  as  expressly
provided  herein,  no issue by the  Company of shares of stock of any class,  or
securities  convertible into shares of stock of any class,  shall affect, and no
adjustment by reason  thereof shall be made with respect to, the number or price
of shares of Common Stock subject to an option.

     b)  CORPORATE  TRANSACTIONS.  In the event of the proposed  dissolution  or
liquidation of the Company, the Offering Period will terminate immediately prior
to the  consummation of such proposed action,  unless otherwise  provided by the
Board. In the event of a proposed sale of all or substantially all of the assets
of the  Company,  or the merger of the Company into  another  corporation,  each
option  under  the Plan  shall  be  assumed  or an  equivalent  option  shall be
substituted  by such  successor  corporation  or a parent or  subsidiary of such
successor corporation,  unless the Board determines, in the exercise of its sole
discretion  and in lieu of such  assumption  or  substitution,  to  shorten  the
Offering  Period  then in  progress  by  setting a new  Purchase  Date (the "New
Purchase  Date").  If the Board shortens the Offering Period then in progress in
lieu of assumption or  substitution  in the event of a merger or sale of assets,
the Board shall notify each participant in writing, at least ten (10) days prior
to the New Purchase Date,  that the Purchase Date for his or her option has been
changed to the New  Purchase  Date and that his or her option will be  exercised
automatically on the New Purchase Date,  unless prior to such date he or she has
withdrawn  from the  Offering  Period as  provided  in Section  10  hereof.  For
purposes of this paragraph,  an option granted under the Plan shall be deemed to
have been assumed or substituted if, following the sale of assets or merger, the
option confers the right to purchase,  for each share of Common Stock subject to
the option  immediately prior to the sale of assets or merger, the consideration
(whether stock,  cash or other  securities or property)  received in the sale of
assets or merger by holders of Common  Stock for each share of Common Stock held
on the  effective  date of the  transaction  (and if such holders were offered a
choice of consideration,  the type of consideration chosen by the holders of the
majority of the outstanding shares of Common Stock); provided,  however, that if
such  consideration  received  in the sale of assets or  merger  was not  solely
common stock of the successor  corporation  or its parent (as defined in Section
424(e)  of the  Code),  the  Board  may,  with  the  consent  of  the  successor
corporation and the  participant,  provide for the  consideration to be received
upon  exercise  of the  option  to be  solely  common  stock  of  the  successor
corporation  or  its  parent  equal  in  fair  market  value  to the  per  share
consideration  received  by  holders  of  Common  Stock in the sale of assets or
merger.

     19. AMENDMENT OR TERMINATION.

     a) The  Board  may at any time  terminate  or amend  the  Plan.  Except  as
provided  in  Section  19, no such  termination  may affect  options  previously
granted,  nor may an amendment make any change in any option theretofore granted
which adversely affects the rights of any participant;  provided, that no shares
may be issued or sold pursuant to any amendment increasing the maximum number of
shares  issuable  under the Plan unless the  stockholders  of the  Company  have
approved the  amendment  within 12 months of its adoption by the Board.  If such
stockholder  approval is not obtained within such 12-month period, the amendment
shall be void and of no force or effect and the amounts  withheld from Employees
with respect to such increased shares shall be returned to them. In addition, to
the extent  necessary to comply with Rule 16b-3 under the Exchange Act, or under
Section 423 of the Code (or any  successor  rule or provision or any  applicable
law or  regulation),  the Company  shall obtain  stockholder  approval in such a
manner and to such a degree as so required.

     b)  Without  stockholder   approval  and  without  regard  to  whether  any
participant rights may be considered to have been adversely affected,  the Board
(or its committee) shall be entitled to change the Offering Periods and Purchase
Periods,  limit the frequency  and/or  number of changes in the amount  withheld
during an Offering  Period,  establish the exchange ratio  applicable to amounts
withheld in currency  other than U.S.  dollars,  permit  payroll  withholding in
excess of the amount  designated by a participant  in order to adjust for delays
or mistakes  in the  Company's  processing  of  properly  completed  withholding
elections, establish reasonable waiting and adjustment periods and/or accounting
and crediting  procedures to ensure that amounts  applied toward the purchase of
Common Stock for each participant properly correspond with amounts withheld from
the  participant's  Compensation,   and  establish  such  other  limitations  or
procedures as the Board (or its committee)  determines in its sole discretion as
advisable which are consistent with the Plan.

     20. NOTICES.  All notices or other  communications  by a participant to the
Company under or in  connection  with the Plan shall be deemed to have been duly
given when received in the form specified by the Company at the location,  or by
the person, designated by the Company for the receipt thereof.

     21. CONDITIONS UPON ISSUANCE OF SHARES.

     a) Shares shall not be issued with respect to an option unless the exercise
of such option and the  issuance and  delivery of such shares  pursuant  thereto
shall  comply  with all  applicable  provisions  of law,  domestic  or  foreign,
including,  without  limitation,  the  Securities  Act of 1933, as amended,  the
Exchange  Act,  the  rules  and  regulations  promulgated  thereunder,  and  the
requirements  of The Nasdaq National Market or any stock exchange upon which the
shares may then be  listed,  and shall be further  subject  to the  approval  of
counsel for the Company with respect to such compliance.

     b) As a condition of the exercise of an option, the Company may require the
person  exercising  such option to represent and warrant at the time of any such
exercise that the shares are being purchased only for investment and without any
present  intention  to sell or  distribute  such  shares  if, in the  opinion of
counsel  for  the  Company,  such a  representation  is  required  by any of the
aforementioned applicable provisions of law.

     c) Each participant  agrees, by enrolling in the Plan, to promptly give the
Company  prior  written   notice  of  any  withdrawal  of  shares  held  in  the
participant's  account  established  under Section 5(c), or any  disposition  of
shares  purchased under the Plan,  where such  withdrawal or disposition  occurs
within  two (2) years  after the date of grant of the option  pursuant  to which
such shares were  purchased,  provided that any such  withdrawal or  disposition
shall be subject to Section 21(d).

     d) Prior to the participant's termination of employment with the Company, a
participant may withdraw some or all of the whole shares of Common Stock held in
the participant's  account established under Section 5(c), provided that, unless
the Board or the committee  administering the Plan otherwise permits in its sole
discretion,  each participant  agrees,  by enrolling in the Plan, that he or she
may not withdraw any shares of Common Stock  purchased  under the Plan until six
(6) months have expired  following  the Purchase  Date on which such shares were
purchased.

     22. TERM OF PLAN;  EFFECTIVE DATE. The Plan shall become effective upon the
earlier  to  occur  of  its  adoption  by  the  Board  or  its  approval  by the
stockholders of the Company.  It shall continue in effect for a term of ten (10)
years unless sooner  terminated under Section 19 hereof.  However,  no shares of
Common  Stock may be issued or sold until the  stockholders  of the Company have
approved  the Plan  within 12  months  of its  adoption  by the  Board.  If such
stockholder approval is not obtained within such 12-month period, the Plan shall
be void and of no force or effect and the amounts  withheld from Employees shall
be returned to them.

     23.  ADDITIONAL  RESTRICTIONS  OF RULE 16B-3.  The terms and  conditions of
options granted  hereunder to, and the purchase of shares by, persons subject to
Section 16 of the Exchange Act shall comply with the  applicable  provisions  of
Rule  16b-3.  This plan  shall be  deemed to  contain,  and such  options  shall
contain,  and the shares issued upon exercise  thereof shall be subject to, such
additional  conditions  and  restrictions  as may be  required  by Rule 16b-3 to
qualify for the  maximum  exemption  from  Section 16 of the  Exchange  Act with
respect to Plan transactions.



                                   Exhibit 5.1

                       [Express Scripts, Inc. Letterhead]

                                December 21, 1998

Express Scripts, Inc.
14000 Riverport Drive
Maryland Heights, Missouri 63043

Ladies and Gentlemen:

     I am Senior Vice President of Administration, General Counsel and Secretary
of Express Scripts,  Inc., a Delaware  corporation (the "Company"),  and in such
capacity I am familiar with the Registration Statement on Form S-8 to which this
opinion is filed as an exhibit (the "Registration  Statement"),  which registers
under the Securities  Act of 1933, as amended (the  "Securities  Act"),  250,000
shares of Class A Common Stock,  par value $0.01,  of the Company (the "Shares")
reserved for  issuance  pursuant to the Express  Scripts,  Inc.  Employee  Stock
Purchase Plan (the "Plan").

     I have examined originals or copies, certified or otherwise,  identified to
my satisfaction,  of such documents,  corporate records,  certificates of public
officials and other  instruments  as I deemed  necessary for the purposes of the
opinion  expressed  herein. I have assumed (i) the genuineness of all signatures
on all  documents  examined  by  me,  (ii)  the  authenticity  of all  documents
submitted to me as originals, (iii) the conformity to authentic originals of all
documents  submitted to me as certified or photostatic  copies, and (iv) the due
authorization, execution and delivery of all documents.

     On  the  basis  of  the  foregoing,  I am of  the  opinion  that  when  the
Registration  Statement,  including any  amendments  thereto,  shall have become
effective  under  the  Securities  Act,  and the  Shares  have  been  issued  in
accordance  with the terms of the Plan,  then the Shares will be legally issued,
fully paid and nonassessable.

     This  opinion is not  rendered  with respect to any laws other than federal
laws and the General  Corporation Law of the State of Delaware.  I do not assume
any duty to update this opinion with respect to changes of law or fact occurring
after the date hereof.

     I consent to the filing of this  opinion as an exhibit to the  Registration
Statement. I also consent to your filing copies of this opinion as an exhibit to
the  Registration  Statement  with  such  agencies  of such  states  as you deem
necessary in the course of complying with the laws of such states  regarding the
offering and sale of the Shares.  In giving this consent,  I do not admit that I
am in the category of persons whose  consent is required  under Section 7 of the
Securities  Act or the rules and  regulations  of the  Securities  and  Exchange
Commission.


                                            Very truly yours,

                                            /S/ Thomas M. Boudreau

                                            Thomas M. Boudreau
                                            Senior Vice President of 
                                            Administration, General Counsel 
                                            and Secretary


                                  Exhibit 23.1

                       Consent of Independent Accountants


     We hereby consent to the  incorporation  by reference in this  Registration
Statement on Form S-8 of:

     - our report  dated  February 6, 1998,  except for Note 13,  which is as of
February 20, 1998, appearing on page 25 of Express Scripts, Inc.'s Annual Report
on Form 10-K for the year ended December 31, 1997; and

     - our report dated April 30, 1998, on our audits of the combined  financial
statements of Value Health Pharmacy Benefit  Management as of December 31, 1996,
and for the years ended  December  31, 1996 , and 1995,  appearing on page 24 of
Express Scripts, Inc.'s Form 8-K/A Amendment No. 1, dated June 12, 1998.



/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP

St. Louis, Missouri
December 23, 1998





                                  Exhibit 23.2

                          Consent of Ernst & Young LLP


     We consent to the incorporation by reference in this Registration Statement
on form S-8 pertaining to the Express Scripts, Inc. Employee Stock Purchase Plan
of our report  dated  June 4,  1998,  with  respect  to the  combined  financial
statements  of Value  Health  Pharmacy  Benefit  Management  included in Express
Scripts,  Inc.'s Current Report on Form 8-K/A,  dated June 12, 1998,  filed with
the Securities & Exchange Commission.


                                          /s/ Ernst & Young LLP
Minneapolis, Minnesota
December 23, 1998



                                  Exhibit 23.3


                          Consent of Ernst & Young LLP

     We consent to the incorporation by reference in this Registration Statement
on Form S-8 pertaining to the Express Scripts, Inc. Employee Stock Purchase Plan
of our report dated June 1, 1998,  with respect to the  financial  statements of
Managed Prescription Network, Inc. d/b/a Columbia Pharmacy Solutions included in
Express Scripts,  Inc.'s Current Report on Form 8-K/A dated June 12, 1998, filed
with the Securities & Exchange Commission.


                                               /s/ Ernst & Young LLP


Pittsburgh, Pennsylvania
December 23, 1998





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