EXPRESS SCRIPTS INC
10-K/A, 1999-06-10
SPECIALTY OUTPATIENT FACILITIES, NEC
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                   FORM 10-K/A



X ANNUAL REPORT  PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES  EXCHANGE ACT
  OF 1934 FOR THE FISCAL YEAR ENDED DECEMBER 31, 1998, OR

  TRANSITION  REPORT  PURSUANT  TO  SECTION  13 OR  15(d)  OF THE  SECURITIES
  EXCHANGE  ACT  OF  1934  FOR  THE  TRANSITION   PERIOD  FROM   ____________
  TO _____________.

                         Commission File Number: 0-20199

                              EXPRESS SCRIPTS, INC.
             (Exact name of registrant as specified in its charter)

        Delaware                                               43-1420563
(State or other jurisdiction                (I.R.S. employer identification no.)
of incorporation or organization)

13900 Riverport Dr., Maryland Heights, Missouri                       63043
(Address of principal executive offices)                           (Zip Code)


       Registrant's telephone number, including area code: (314) 770-1666

           Securities registered pursuant to Section 12(b) of the Act:

                                      None

           Securities registered pursuant to Section 12(g) of the Act:

                      Class A Common Stock, $0.01 par value
                                (Title of Class)

     Indicate  by check mark  whether the  registrant  (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days. Yes X No ___

     Indicate by check mark if disclosure of delinquent  filers pursuant to Item
405 of Regulation of S-K is not contained herein, and will not be contained,  to
the  best  of  Registrant's   knowledge,  in  definitive  proxy  or  information
statements  incorporated  by  reference  in Part  III of this  Form  10-K or any
amendment to this Form 10-K. [X]

     The  aggregate   market  value  of   Registrant's   voting  stock  held  by
non-affiliates as of March 1, 1999, was $1,207,562,195  based on 18,158,830 such
shares held on such date by non-affiliates and the last sale price for the Class
A Common Stock on such date of $66.50 as reported on the Nasdaq National Market.
Solely for purposes of this  computation,  the  Registrant  has assumed that all
directors  and  executive  officers  of the  Registrant  and  NYLIFE  HealthCare
Management, Inc. are affiliates of the Registrant.

Common stock outstanding as of March 1, 1999:     18,206,130  Shares Class A
                                                  15,020,000  Shares Class B

                       DOCUMENTS INCORPORATED BY REFERENCE

     Part  III  incorporates  by  reference  portions  of the  definitive  proxy
statement for the  Registrant's  1999 Annual Meeting of  Stockholders,  which is
expected to be filed with the Securities and Exchange  Commission not later than
120 days after the registrant's fiscal year ended December 31, 1998.
- --------------------------------------------------------------------------------
                                     PART I
                                   THE COMPANY

Forward Looking Statements and Associated Risks

     Information  that we have  included or  incorporated  by  reference in this
Annual Report on Form 10-K, and  information  that may be contained in our other
filings with the  Securities and Exchange  Commission  (the "SEC") and our press
releases or other  public  statements,  contain or may  contain  forward-looking
statements.  These forward looking statements include, among others,  statements
of our plans, objectives,  expectations or intentions, including as to Year 2000
issues.

     Our forward-looking statements involve risks and uncertainties.  Our actual
results  may differ  significantly  from those  projected  or  suggested  in any
forward-looking  statements.  We do not  undertake  any  obligation  to  release
publicly any revisions to such  forward-looking  statements to reflect events or
circumstances  occurring  after the date hereof or to reflect the  occurrence of
unanticipated  events.  Factors  that  might  cause such a  difference  to occur
include, but are not limited to:

     -risks  associated  with the  consummation of  acquisitions,  including the
ability to successfully integrate the operations of acquired businesses with our
existing operations, client retention issues, and risks inherent in the acquired
entities operations

     -risks  associated  with obtaining  financing and capital


     -risks  associated with our ability to manage and maintain interal growth


     -competition including  price  competition,  competition  in the bidding
and  proposal process and our ability to consummate  contract  negotiations
with  prospective clients


     -the  possible termination  of  contracts  with  key  clients  or
providers

     -the possible loss of relationships with pharmaceutical manufacturers,  or
changes  in  pricing,  discount,  rebate or other  practices  of  pharmaceutical
manufacturers


     -adverse results in litigation

     -adverse results in regulatory matters, the adoption of adverse legislation
or  regulations,   more  aggressive   enforcement  of  existing  legislation  or
regulations,  or a change  in the  interpretation  of  existing  legislation  or
regulations

     -developments  in  the  health  care  industry,  including  the  impact  of
increases  in health  care  costs,  changes  in drug  utilization  patterns  and
introductions of new drugs

     -risks associated with the "year 2000" issue

     -dependence on key members of management


     -risks associated with our ability to meet our debt obligations


     -our  relationship  with new york life insurance  company,  which possesses
voting control of the company

     -other risks described from time to time in our filings with the sec


These and other relevant factors,  including any other  information  included or
incorporated by reference in this Report,  and information that may be contained
in our other filings with the SEC, should be carefully considered when reviewing
any  forward-looking  statement.  The  occurrence of any of the following  risks
could  materially  adversely  affect our  business,  results of  operations  and
financial condition.

Failure to Integrate ValueRx and DPS Could Adversely Affect Our Business

         On April 1, 1998, we completed our first major acquisition by acquiring
ValueRx,  the  pharmacy  benefit  management  ("PBM")  business of  Columbia/HCA
Healthcare Corporation, for approximately $460 million in cash. This transaction
significantly   increased  our  membership   base  and  the  complexity  of  our
operations. In the second quarter of 1999, we expect to complete our acquisition
of Diversified  Pharmaceutical  Services,  Inc. and  Diversified  Pharmaceutical
Services  (Puerto Rico),  Inc.  (collectively,  "DPS") from  SmithKline  Beecham
Corporation and one of its affiliates for $700 million in cash.  Consummation of
the  transaction  is  subject to  customary  closing  conditions,  and we cannot
provide any assurance that all such  conditions  will be satisfied such that the
transaction  may  be  consummated.   If   consummated,   the  transaction   will
approximately  double our membership base and further increase the complexity of
our  operations.  In light of both  acquisitions,  we have developed and, in the
case of ValueRx,  begun to implement,  an integration plan to address items such
as:

     o     retention of key employees
     o     consolidation of administrative and other duplicative functions
     o     coordination of sales, marketing, customer service and clinical
               functions
     o     systems integration
     o     new product and service development
     o     client retention and other items


         While we have  achieved  many of our  integration  goals  to date  with
respect  to  the  acquisition  of  ValueRx,   certain  significant   integration
challenges  remain,  including  the  complete  integration  of  our  information
technology  systems.  We cannot provide any assurance that our integration  plan
will  successfully  address  all  aspects  of our  operations,  or  that we will
continue to achieve our integration goals. In the case of DPS, we cannot provide
any assurance  that our  integration  plan will address all relevant  aspects of
DPS's  business  or that we will be  able  to  implement  our  integration  plan
successfully.  In addition,  we assumed specific financial targets when deciding
to purchase  ValueRx and DPS. We cannot  provide any  assurance  that we will be
able to achieve  our  targets.  Finally,  although  we  conducted  an  extensive
investigation  in evaluating our acquisitions of ValueRx and DPS, it is possible
that we failed to  uncover  or  appropriately  address  material  problems  with
ValueRx's  or DPS's  operations  or financial  condition,  or failed to discover
contingent  liabilities.  Any of the foregoing could materially adversely affect
our results of operations or financial condition.


Failure to Obtain Financing or Capital Could Adversely Affect Our Business


         Our ability to consummate the DPS transaction is dependent upon,  among
other things, our securing financing of approximately $1.05 billion,  consisting
of an $750  million  term loan  facility  and a $300  million  revolving  credit
facility,  for which we have  obtained a  commitment  from Credit  Suisse  First
Boston  ("CSFB").  This new credit  facility is intended to replace our existing
$440 million  facility with Bankers Trust  Company.  The commitment for this new
facility  is,  however,  subject to  various  conditions,  which we believe  are
customary for  transactions  of this kind,  but we cannot  provide any assurance
that all such  conditions  will be satisfied so that this credit facility can be
funded.  We have also obtained a commitment  from CSFB for a $150 million bridge
loan which may be needed to  facilitate  the  closing of the  acquisition.  This
commitment  is also subject to various  conditions,  which we again  believe are
customary  for  transactions  of this  kind.  However,  we  cannot  provide  any
assurance  that all such  conditions  will be satisfied so that this bridge loan
facility will be funded.

         We have recently  filed a  registration  statement,  which has not been
declared   effective,   with  the  SEC  for  a  proposed   primary  offering  of
approximately  $350  million  of  Class A Common  Stock.  The  proceeds  of this
offering,  which  will be made only by means of a  prospectus,  would be used to
retire the bridge loan, if funded,  and repay a portion of the debt  outstanding
under the new  credit  facility,  assuming  it is also  funded.  Our  ability to
complete the stock offering is subject to investors' willingness to purchase the
shares and other typical market risks,  which we cannot control,  as well as the
success of the Company. We cannot, therefore, provide any assurance that we will
be able to successfully  complete this offering,  and if we fail to complete the
offering as planned,  our financial condition and future operating results could
be materially adversely affected.


Failure to Manage and Maintain Internal Growth Could Adversely Affect Our
Business

     We have experienced  rapid internal growth over the past several years. Our
ability to  effectively  manage and maintain this  internal  growth will require
that we continue to improve our financial and management  information systems as
well as identify and retain key  personnel.  We can provide no assurance that we
will  successfully  meet  these  requirements  or that we will  have  access  to
sufficient  capital to do so. Our  internal  growth is also  dependent  upon our
ability to attract new clients and achieve growth in the membership  base of our
existing clients. If we are unable to continue our client and membership growth,
our results of operations and financial  position could be materially  adversely
affected.


Competition in the PBM Industry Could Reduce Our Membership and Our Profit
Margins

     Pharmacy benefit management is a very competitive business. Our competitors
include  several  large and  well-established  companies  which may have greater
financial,   marketing  and  technological  resources  than  we  do.  One  major
competitor in the PBM business,  Merck-Medco  Managed Care,  L.L.C., is owned by
Merck  &  Co.,  Inc.,  a  large  pharmaceutical   manufacturer.   Another  major
competitor, PCS, Inc., is owned by Rite-Aid Corporation, a large retail pharmacy
chain. Both of these competitors may possess purchasing or other advantages over
us by virtue of their  ownership,  and could  succeed in taking away some of our
clients.   Consolidation  in  the  PBM  industry  may  also  lead  to  increased
competition among a smaller number of large PBM companies.  Competition may also
come from other sources in the future,  including from Internet-based  providers
such as Drugstore.com and  PlanetRx.com.  We cannot predict what effect, if any,
these new competitors may have on the marketplace or on our business.


         Over the last several years intense  competition in the marketplace has
caused many PBMs, including us, to reduce the prices charged to clients for core
services and share a larger portion of the formulary  fees and related  revenues
received from drug manufacturers with clients. This combination of lower pricing
and increased  revenue sharing has caused our operating  margins to decline (see
"Management's  Discussion  and  Analysis of Financial  Condition  and Results of
Operations").  We expect to continue  marketing our services to larger  clients,
who typically have greater  bargaining  power than smaller  clients.  This might
create  continuing  pressure on our margins.  We can give no assurance  that new
services  provided to these  clients  will fully  compensate  for these  reduced
margins.


Failure to Retain Key Clients and Network Pharmacies Could Adversely Affect Our
Business and Limit Our Access to Retail Pharmacies

     We currently provide PBM services to approximately 8,500 clients, including
several large clients.  Our  acquisitions  have  diversified our client base and
reduced our dependence on any single client.  After giving effect to the pending
DPS  acquisition,  our top 10  clients,  measured  as of January  1,  1999,  but
excluding United  HealthCare  Corporation,  represent  approximately  27% of our
total  membership  base,  but no single  client  would,  on a combined pro forma
basis,  represent  more  than  approximately  6% of  our  membership  base.  Our
contracts  with  clients  generally do not have terms of longer than three years
and in some cases are terminable by either party on relatively short notice. Our
larger clients  generally  distribute  requests for proposals and seek bids from
other PBM providers in advance of the expiration of their contracts.  If several
of these large  clients elect not to extend their  relationship  with us, and we
are not successful in generating sales to replace the lost business,  our future
business and  operating  results  could be  materially  adversely  affected.  In
addition,  we believe  the  managed  care  industry  is  undergoing  substantial
consolidation, and some of our managed care clients could be acquired by another
party that is not our client.  In such case,  the  likelihood  such client would
renew its PBM contract with us could be reduced.

     Assuming  consummation of the pending DPS  acquisition,  United  HealthCare
Corporation  will be our largest client,  with  approximately 10 million members
and account for  approximately  22% of our membership  base. DPS's contract with
United  HealthCare  will  expire on May 31,  2000,  and  United  HealthCare  has
indicated it will be moving to another  provider at that time.  In our financial
analysis of the DPS  acquisition,  we assumed United  HealthCare would not renew
its  contract.  However,  if we are  unable  to  reduce  our  costs  on a  basis
commensurate  with our  expectations  and  manage the  transition  of this large
client to another provider both efficiently and effectively,  the termination of
this  contract  may  materially  adversely  affect our  business  and results of
operations.

     Our largest  national  provider network consists of more than 52,000 retail
pharmacies, which represent more than 99% of the retail pharmacies in the United
States.  However, the top 10 retail pharmacy chains represent  approximately 41%
of the 52,000  pharmacies,  with these pharmacy chains  representing even higher
concentrations in certain areas of the United States.  Our contracts with retail
pharmacies, which are non-exclusive, are generally terminable by either party on
relatively  short  notice.  If one or more of the top pharmacy  chains elects to
terminate its relationship with us, our members' access to retail pharmacies and
our business  could be  materially  adversely  affected.  In addition,  Rite-Aid
Corporation recently acquired one of our major PBM competitors,  PCS, Inc. Other
large pharmacy chains either own PBMs today or could attempt to acquire a PBM in
the future.  Ownership of PBMs by retail  pharmacy  chains  could have  material
adverse  effects  on our  relationships  with such  pharmacy  chains  and on our
business and results of operations.

Loss of Relationships with Pharmaceutical Manufacturers and Changes in the
Regulation of Discounts and Rebates Provided to Us by Pharmaceutical
Manufacturers Could Decrease Our Profits

     We  maintain   contractual   relationships  with  numerous   pharmaceutical
manufacturers which provide us with:

o    discounts  at the time we  purchase  the drugs to be  dispensed  from our
     mail pharmacies

o    rebates  based upon sales of drugs  from our mail  pharmacies  and
     through  pharmacies in our retail networks

o    administrative  fees based upon the development  and  maintenance  of
     formularies which include  the particular manufacturer's  products

These  fees  are  all  commonly  referred  to as  formulary  fees  or  formulary
management fees.

     We also provide  various  services for, or services which are funded wholly
or partially by, pharmaceutical manufacturers. These services include:

o    compliance   programs,   which  involve   instruction  and
     counseling  of  patients   concerning  the  importance  of
     compliance with the drug treatment  regimen  prescribed by
     their physician

o    therapy  management  programs,  which involve education of
     patients  having  specific  diseases,  such as asthma  and
     diabetes, concerning the management of their condition

o    market  research  programs in which we provide information to manufacturers
     concerning drug utilization patterns.

These arrangements are generally  terminable by either party on relatively short
notice. If several of these arrangements are terminated or materially altered by
the  pharmaceutical  manufacturers,  our  operating  results could be materially
adversely affected. In addition,  formulary fee programs, as well as some of the
services we provide to the pharmaceutical  manufacturers,  have been the subject
of debate in federal and state  legislatures  and various  other public  forums.
Changes in existing  laws or  regulations  or in their  interpretations,  or the
adoption  of new laws or  regulations,  relating  to any of these  programs  may
materially adversely affect our business.

     Patents  covering  many brand name drugs that  currently  have  substantial
market share will expire over the next several years,  and generic drugs will be
introduced  at prices that may  substantially  reduce the market  share of these
brand name drugs. Unlike brand name drug manufacturers, manufacturers of generic
drugs do not generally  offer  incentive  payments on their drugs to PBMs in the
form of discounts, rebates or other formulary fees. Although we expect new drugs
with  patent  protection  to be  introduced  in the  future,  we can  provide no
assurance  such drugs will capture a  significant  share of the market such that
our incentive payment revenues will not be reduced.

Pending and Future Litigation Could Materially Affect Our Relationships with
Pharmaceutical Manufacturers or Subject Us to Significant Monetary Damages


     Since 1993, retail pharmacies have filed over 100 separate lawsuits against
drug  manufacturers,  wholesalers and certain PBMs,  challenging brand name drug
pricing practices under various state and federal antitrust laws. The plaintiffs
alleged,  among other things,  that the manufacturers  had offered,  and certain
PBMs had  knowingly  accepted,  discounts and rebates on purchases of brand name
prescription  drugs  that  violated  the  federal  Sherman  Act and the  federal
Robinson-Patman  Act.  Some  manufacturers  settled  certain  of these  actions,
including a Sherman Act case brought on behalf of a  nationwide  class of retail
pharmacies.  The class action settlements  generally provided for commitments by
the manufacturers in their discounting practices to retail pharmacies. The class
action was recently  dismissed as to drug  manufacturers and wholesalers who did
not settle.  With respect to the cases filed by plaintiffs  who opted out of the
class  action,  while  some drug  manufacturers  have  settled  certain of these
actions, such settlements are not part of the public record.

     Neither we nor DPS is  currently  a party to any of these  proceedings.  To
date,  we do not believe any of these  settlements  have had a material  adverse
effect on our business.  However, we cannot provide any assurance that the terms
of the settlements will not materially adversely affect us in the future or that
we will not be made a party to any  separate  lawsuit.  In  addition,  we cannot
predict the outcome or possible  ramifications  to our  business of the cases in
which the plaintiffs are trying their claims separately.

     We are also  subject to risks  relating to  litigation  and  liability  for
damages in  connection  with our PBM  operations,  including  the  dispensing of
pharmaceutical  products  by our  mail  pharmacies,  the  services  rendered  in
connection  with our  formulary  management  and  informed  decision  counseling
services,  and our non-PBM  operations,  including  the  products  and  services
provided in connection  with our infusion  therapy  programs (and the associated
nursing  services).  We believe our  insurance  protection  is adequate  for our
present  operations.  However,  we cannot  provide any assurance that we will be
able to maintain our professional and general  liability  insurance  coverage in
the future or that such insurance coverage will be available on acceptable terms
to cover any or all  potential  product  or  professional  liability  claims.  A
successful  product or  professional  liability claim in excess of our insurance
coverage could have a material adverse effect on our business.


Changes in State and Federal Regulations Could Restrict Our Ability to Conduct
Our Business


     Numerous  state and federal  laws and  regulations  affect our business and
operations. The categories include, but are not necessarily limited to:


o    health care fraud and abuse laws and  regulations, which  prohibit illegal
     referral and other payments

o    the Employee  Retirement  Income Security Act and related regulations,
     which regulate many  health care plans


o    proposed comprehensive state PBM legislation


o    consumer protection laws and regulations

o    pharmacy network access laws, including "any willing provider" and "due
     process" legislation, that regulate aspects of our pharmacy network
     contracts

o    legislation imposing benefit plan design restrictions, which limit how
     our clients can design their drug benefit plans

o    various licensure laws, such as managed care and third party administrator
     licensure laws

o    drug pricing legislation, including "most favored nation" pricing and
     "unitary pricing" legislation

o    mail pharmacy laws and regulations

o    privacy and confidentiality laws and regulations

o    Medicare prescription drug coverage proposals

o    other Medicare and Medicaid reimbursement regulations


o    potential regulation of the PBM industry by the U.S. Food and Drug
     Administration

These and other regulatory  matters are discussed in more detail under "Business
- - Government Regulation" below.


     We believe we are operating our business in substantial compliance with all
existing  legal  requirements  material to the operation of our business.  There
are,  however,  significant  uncertainties  regarding the application of many of
these legal  requirements  to our business,  and we cannot provide any assurance
that a  regulatory  agency  charged  with  enforcement  of any of these  laws or
regulations  will not interpret them  differently or, if there is an enforcement
action brought against us, that our interpretation  would prevail.  In addition,
there are numerous  proposed health care laws and regulations at the federal and
state levels,  many of which could materially  affect our ability to conduct our
business or adversely affect our results of operations. We are unable to predict
what additional  federal or state  legislation or regulatory  initiatives may be
enacted in the future  relating to our  business or the health care  industry in
general.  We also cannot predict what effect any such legislation or regulations
might have on us. We also cannot  provide any  assurance  that  federal or state
governments will not impose additional  restrictions or adopt interpretations of
existing  laws that could  have a material  adverse  effect on our  business  or
results of operations.

Efforts to Reduce Health Care Costs and Alter Health Care Financing Practices
Could Adversely Affect Our Business


     Efforts are being made in the United  States to control  health care costs,
including prescription drug costs, in response to, among other things, increases
in prescription  drug  utilization  rates and drug prices.  If these efforts are
successful  or  if  prescription   drug  utilization   rates  were  to  decrease
significantly,  our  business  and  results of  operations  could be  materially
adversely affected.

     We have  designed our business to compete  within the current  structure of
the U.S.  health  care  system.  Changing  political,  economic  and  regulatory
influences may affect health care financing and reimbursement  practices. If the
current health care financing and  reimbursement  system changes  significantly,
our  business  could be  materially  adversely  affected.  Congress is currently
considering proposals to reform the U.S. health care system. These proposals may
increase governmental involvement in health care and PBM services, and otherwise
change the way our clients do business.  Health care  organizations may react to
these  proposals and the  uncertainty  surrounding  them by reducing or delaying
purchases of cost control  mechanisms and related  services that we provide.  We
cannot predict what effect,  if any,  these  proposals may have on our business.
Other  legislative  or  market-driven  changes in the health care system that we
cannot anticipate could also materially adversely affect our business.


Failure to Successfully Address the Year 2000 Issue Could Adversely Affect Our
Business


     Our business  relies  heavily on computers  and other  information  systems
technology.  In 1995, we began addressing the "Year 2000" issue, which generally
refers to the  inability  of  certain  computer  systems to  properly  recognize
calendar  dates beyond  December 31, 1999.  We developed a Year 2000  compliance
plan to address:

     o        internally developed application software
     o        vendor developed application software
     o        operating system software
     o        utility software
     o        vendor/trading partner-supplied files
     o        externally provided data or transactions
     o        non-information technology devices
     o        adherence to applicable industry standards

See "Management's Discussion and Analysis of Financial Conditions and Results of
Operations" for additional information on our Year 2000 efforts.

     We believe that with  appropriate  modifications  to our existing  computer
systems,  updates by our vendors  and trading  partners  and  conversion  to new
software in the ordinary  course of our  business,  the Year 2000 issue will not
pose material  operational  problems for us. However, if the conversions are not
completed in a proper and timely manner by all affected parties, or if our logic
for communicating with noncompliant systems is ineffective,  the Year 2000 issue
could result in material adverse  operational and financial  consequences to us.
We cannot  provide any assurance  that our efforts,  or those of our vendors and
trading partners (who are beyond our control),  will be successful in addressing
the Year 2000 issue.  In addition,  while DPS has  represented to us that it has
implemented a Year 2000 plan for upgrading its computer systems and communicated
with its vendor/trading  partners regarding such partners' Year 2000 compliance,
we cannot predict  whether such plan will  adequately  address all of DPS's Year
2000 issues or whether DPS's  vendors/trading  partners will adequately  address
their Year 2000  issues.  Failure  by DPS and its  vendors/trading  partners  to
adequately  address the Year 2000 issue could have a material  adverse effect on
our business and results of  operations.  We also cannot  provide any  assurance
that our  contingency  plan,  or that of DPS,  will be complete  and  adequately
address all possible contingencies. The failure of our contingency plan, or that
of DPS, could result in material adverse operational and financial  consequences
to us.

Loss of Key Management Could Adversely Affect Our Business


     Our success is  materially  dependent  upon  certain key  managers  and, in
particular,  upon the continued  services of Barrett A. Toan,  our President and
Chief Executive  Officer.  Our future  operations could be materially  adversely
affected if the services of Mr. Toan cease to be available.  The Company and Mr.
Toan are parties to an employment agreement which currently extends to March 31,
2002,  and which  automatically  extends for an additional  one year on April 1,
2001,  and on each  April 1  thereafter  unless  either  party  gives  notice of
termination  at least  30 days  prior  to such  April 1. As of the date  hereof,
neither we nor Mr. Toan has given such notice.

Failure to Meet Our Debt Obligations Could Adversely Affect Our Results of
Operations and Financial Condition

     In  connection  with  our  pending  acquisition  of DPS,  we  will  incur a
substantial  amount of  indebtedness  under our proposed  $1.05  billion  credit
facility discussed above. If funded, this credit facility will be secured by the
capital  stock  of each  of our  existing  and  subsequently  acquired  domestic
subsidiaries,  excluding  Practice Patterns Science,  Great Plains  Reinsurance,
ValueRx of Michigan,  Diversified NY IPA and Diversified Pharmaceutical Services
(Puerto  Rico),  and 65% of the  stock of our  foreign  subsidiaries.  If we are
unable to meet our  obligations  under  this  proposed  credit  facility,  these
creditors  could exercise their rights as a secured party and take possession of
the pledged capital stock of these subsidiaries. This would materially adversely
affect our results of operations and financial condition.

Our Leverage and Debt Service Obligations Could Impede Our Operations and
Flexibility

     After  consummation  of the  pending  DPS  acquisition  and  funding of the
proposed $1.05 billion credit facility, we will have substantial leverage, which
means that the amount of our outstanding  debt will be large compared to the net
book value of our assets, and we will have substantial repayment obligations and
interest expense. We and our subsidiaries may also incur additional indebtedness
in the future.

     Our level of debt and the  limitations  which  will be imposed on us by our
debt agreements could have important consequences including the following:

     o    we will have to use a substantial portion of our cash flow from
          operations for debt  service  rather  than for our  operations

     o    we may not be able to  obtain additional debt financing for future
          working  capital,  capital  expenditures or other corporate purposes

     o    some of the debt under our proposed  $1.05 billion  credit
          facility  may be at a variable  interest  rate,  making us
          vulnerable to increases in interest rates

     o    we could be less  able to take  advantage  of  significant
          business opportunities, such as acquisition opportunities,
          and react to changes in market or industry conditions.

     o    we could be more vulnerable to general adverse economic and industry
          conditions

     o    we may be disadvantaged compared to competitors with less leverage

     Furthermore,  our ability to satisfy our  obligations,  including  our debt
service requirements,  will be dependent upon our future performance, which will
be  subject to  numerous  factors,  including,  without  limitation,  prevailing
economic conditions and financial, business and other factors, many of which are
beyond our control and which affect our business and operations.

New York Life Insurance Company Can Control Our Business and Limit Our Ability
to Enter Into Selected Business Transactions


     We have two classes of authorized  common  stock:  Class A Common Stock and
Class B Common Stock.  Our Class A Common Stock has been publicly  traded on The
Nasdaq  National Market since June 9, 1992. Our Class B Common Stock is entirely
owned by NYLIFE HealthCare Management,  Inc. ("NYLIFE HealthCare"),  an indirect
subsidiary of New York Life Insurance  Company ("New York Life").  Each share of
our Class A Common  Stock has one vote per share,  and each share of our Class B
Common stock has ten votes per share.  Consequently,  although NYLIFE HealthCare
currently owns  approximately 45% of the Company's total  outstanding  shares of
Common Stock,  it possesses  approximately  89% of the combined  voting power of
both classes of Common Stock.  NYLIFE HealthCare could reduce its Class B Common
Stock  ownership to represent  slightly  less than 10% of the total  outstanding
shares of our common  stock and still  control a majority of the voting power of
our  common  stock.  Accordingly,  without  regard  to the  votes of our  public
stockholders, NYLIFE HealthCare can

     o    elect or remove all of our directors

     o    amend our certificate of incorporation, except where the separate
          approval of the holders of our Class A Common Stock is
          required by law

     o    accept or reject a merger, sale of assets or other major corporate
          transaction

     o    accept or reject any  proposed  acquisition  of the  Company

     o    determine  the amount and timing of dividends  paid to itself and
          holders of our Class A Common Stock


     o    except in limited circumstances, otherwise control our management and
          operations and decide all matters submitted for a stockholder vote

     Our Class B common stock will automatically convert into the same number of
shares of our Class A common  stock upon  transfer by NYLIFE  HealthCare  to any
entity  other than an  affiliate  of New York Life or otherwise at the option of
NYLIFE HealthCare.  We cannot assure you, however, that our Class B common stock
would automatically  convert into our Class A common stock if New York Life were
to transfer the stock of NYLIFE HealthCare to someone who is not an affiliate of
New York Life.


Item 1 - Business

Industry Overview

     Prescription  drug costs are the fastest  growing  component of health care
costs in the  United  States.  The U.S.  Health  Care  Financing  Administration
("HCFA") estimates that pharmaceuticals currently account for approximately 6.5%
of U.S.  health care  expenditures,  and are expected to increase to 8% by 2007.
Estimated U.S. pharmaceutical sales for 1998 were approximately $75 billion, and
HCFA  projects  continued  sales  increases at an average  annual growth rate of
approximately  10% through  2007,  compared to an average  annual growth rate of
approximately  7% for total  health  care  costs  during  this  period.  Factors
underlying this trend include:


     o    increases  in research and  development  expenditures  by drug
          manufacturers, resulting  in many  new  drug  introductions

     o    a  shorter  U.S.  Food  and Drug Administration  approval  cycle for
          new  pharmaceuticals

     o    high  prices for new "blockbuster"  drugs

     o    an aging  population o increased  demand for prescription drugs due to
          increased disease awareness by patients, effective direct-to-consumer
          advertising by drug manufacturers and a growing reliance on medicatio
          in lieu of lifestyle changes


     Health benefit  providers  have been seeking ways to better  understand and
control  drug  costs.   PBMs  help  health   benefit   providers  to  provide  a
cost-effective  drug benefit and to better understand the impact of prescription
drug  utilization  on  total  health  care  expenditures.  PBMs  coordinate  the
distribution   of   outpatient   pharmaceuticals   through  a   combination   of
benefit-management  services, including retail drug card programs, mail pharmacy
services and formulary management programs.

     PBMs emerged during the late 1980s by combining traditional pharmacy claims
processing and mail pharmacy  services to create an integrated  product offering
that could help manage the  prescription  drug  benefit  for payors.  During the
early  1990s,  numerous  PBMs were  created,  with  some  providers  offering  a
comprehensive, integrated package of services.

     The  services  offered by the more  sophisticated  PBMs have  broadened  to
include disease management  programs,  compliance  programs,  outcomes research,
drug therapy management programs and sophisticated data analysis. These advanced
capabilities require resources that may not be available to all PBMs, so further
industry  consolidation  may  occur.  If  prescription  drug costs  continue  to
escalate and become an even larger portion of overall health care  expenditures,
more advanced  capabilities  will be needed to manage these costs so that health
benefit providers will be able to continue to offer a quality  prescription drug
benefit to their  members.  The more  sophisticated  PBMs  should be in the best
position to offer these services.

Company Overview


     We  are  the  largest   full-service  PBM  independent  of   pharmaceutical
manufacturer  or drug store  ownership in North  America.  PBMs  coordinate  the
distribution  of outpatient  pharmaceuticals  through a  combination  of benefit
management  services,   including  retail  drug  card  programs,  mail  pharmacy
services,  drug  formulary  management  programs and other  clinical  management
programs.  We provide  these types of services for  approximately  8,500 clients
that include HMOs, health insurers,  third-party  administrators,  employers and
union-sponsored  benefit plans. We believe our independence from  pharmaceutical
manufacturer  ownership allows us to make unbiased formulary  recommendations to
our clients,  balancing  both  clinical  efficacy and cost.  We also believe our
independence  from drug  store  ownership  allows us to  construct  a variety of
convenient and cost-effective retail pharmacy networks for our clients,  without
favoring any particular pharmacy chain.


     Before 1998,  our growth was driven  almost  exclusively  by our ability to
expand our product offerings and increase our client and membership base through
internally  generated  growth.  From 1992 through 1997, our net revenues and net
income  increased at compound annual growth rates of 58% and 49%,  respectively.
While our  internal  growth  strategy  remains a major focus,  we have  recently
complemented  our internal growth  strategy with two  substantial  acquisitions.
These  acquisitions  add to the scale of our  membership  base and  broaden  our
product  offerings.  In April 1998, we acquired  "ValueRx",  the PBM business of
Columbia/HCA Healthcare Corporation. In the second quarter of 1999, we expect to
complete  the  acquisition  of  DPS,  the PBM  business  of  SmithKline  Beecham
Corporation.  Upon  completion of our acquisition of DPS, we will continue to be
the third  largest PBM in North America in terms of total  members,  and we will
have one of the largest managed care membership bases of any PBM.


     As of January 1, 1999, our PBM services were provided to  approximately  23
million  members in the United  States  and Canada who were  enrolled  in health
plans  sponsored  by our  clients.  Although  membership  counts  are  based  on
eligibility data, they necessarily  involve some estimates,  extrapolations  and
approximations.  For example,  some plan designs allow for family coverage under
one  identification  number, and we make assumptions about the average number of
persons per family.  These  assumptions may vary between us and our competitors.
Consequently,  membership  counts  may  not be  comparable  between  us and  our
competitors.  However,  we believe our  membership  count  provides a reasonable
estimation  of the  population  we serve,  and can be used as one measure of our
growth.  As of January  1, 1999,  some of our  largest  clients  were Aetna U.S.
Healthcare and the State of New York Empire Plan Prescription Drug Program.

     Our PBM  services  are  primarily  delivered  through  networks  of  retail
pharmacies that are under  non-exclusive  contract with us and through five mail
pharmacy  service  centers that we own and operate.  Our largest retail pharmacy
network includes more than 52,000 retail pharmacies,  representing more than 99%
of  all  retail   pharmacies  in  the  United  States.  In  1998,  we  processed
approximately  113.2  million  network  pharmacy  claims  and 7.4  million  mail
pharmacy  prescriptions,  with an estimated total drug spending of approximately
$4.5 billion.

         Our PBM offerings include:


     o    network claims  processing,  mail pharmacy  services,  benefit
          design  consultation,   drug  utilization  review,   formulary
          management  programs,  disease management and medical and drug
          data analysis services,  and compliance and therapy management
          programs for our clients

     o    market research programs for pharmaceutical manufacturers

     o    medical  information   management   services,   which  include
          provider  profiling  and  outcome  assessments,   through  our
          majority owned  subsidiary  Practice  Patterns  Science,  Inc.
          ("PPS")

     o    informed decision counseling services through our Express Health
          LineSM division


         Our non-PBM offerings include:


     o    infusion therapy services through our wholly owned subsidiary IVTx,
          Inc. ("IVTx")

     o    distribution of pharmaceuticals requiring special handling or
          packaging through our Specialty Distribution division


     Our PBM and non-PBM  operations  include  delivery of a variety of tangible
products and services to our members.  However,  our net revenues are  primarily
generated from the delivery of tangible products through our contractual network
of  pharmacies,  mail  pharmacy  services,  infusion  therapy  services  and our
specialty  distribution  business. In 1996, 1997 and 1998, net revenues from the
delivery  of  products  to our  members  represented  97.3%,  97.7%  and  98.3%,
respectively,  of our total net revenues. Revenues from other services comprised
the remainder of our net revenues.

     Express  Scripts,  Inc. was incorporated in Missouri in September 1986, and
was  reincorporated  in Delaware  in March  1992.  We have two classes of common
stock,  Class A Common Stock and Class B Common Stock. Each share of the Class B
Common  Stock is  entitled  to ten  votes,  and each share of the Class A Common
Stock is entitled to one vote. All of the issued and  outstanding  shares of the
Class B Common Stock are owned by NYLIFE  HealthCare.  Our  principal  executive
offices are located at 13900 Riverport Drive, Maryland Heights,  Missouri 63043.
Our telephone number is (314) 770-1666.


Products and Services


Pharmacy Benefit Management

     Overview.   Our  PBM  services   involve  the   management   of  outpatient
prescription  drug usage to foster high quality,  cost-effective  pharmaceutical
care through the application of managed care principles and advanced information
technologies.  We offer our PBM services to our clients in the United States and
Canada. Our PBM offerings include:

     o        retail pharmacy network administration
     o        mail pharmacy services
     o        benefit plan design consultation
     o        formulary administration
     o        electronic point-of-sale claims processing
     o        drug utilization review
     o        the development of advanced formulary compliance and therapeutic
              intervention programs
     o        therapy management  services such as prior  authorization,
              therapy  guidelines,  step therapy protocols and formulary
              management interventions
     o        sophisticated management information reporting and analytic
              services
     o        provider profiling and outcomes assessments
     o        informed decision counseling


     During  1998,  97.9% of our net revenues  were  derived from PBM  services,
compared to 96.8% and 96.1%  during 1997 and 1996,  respectively.  The number of
retail pharmacy  network claims processed and mail pharmacy claims processed has
increased to 113.2 million and 7.4 million claims,  respectively,  in 1998, from
26.3  million and 1.6 million  claims,  respectively,  in 1994.  During 1997 and
1996, we processed 73.2 million and 57.8 million retail pharmacy network claims,
respectively,   and  3.9  million  and  2.8  million   mail   pharmacy   claims,
respectively.

     Retail Pharmacy Network Administration.  We contract with retail pharmacies
to provide  prescription  drugs to members of the pharmacy benefit plans managed
by us. In the United States,  these pharmacies  typically  discount the price at
which they will provide drugs to members in return for  designation as a network
pharmacy.  We manage  four  nationwide  networks  in the  United  States and one
nationwide network in Canada that are responsive to client  preferences  related
to cost  containment  and  convenience  of access for  members.  We also  manage
networks of  pharmacies  that are under  direct  contract  with our managed care
clients or networks that we have designed to meet the specific  needs of some of
our larger clients.

     All retail pharmacies in our pharmacy networks  communicate with us on-line
and in real time to process  prescription  drug claims.  When a member of a plan
presents  his or her  identification  card at a network  pharmacy,  the  network
pharmacist sends the specified claim data in an industry-standard format through
our  systems,  which  process the claim and respond to the  pharmacy,  typically
within one or two seconds. The electronic processing of the claim involves:


     o    confirming the member's eligibility for benefits under the
          applicable  health  benefit plan and the  conditions to or
          limitations of coverage,  such as the amount of copayments
          or deductibles the member must pay


     o    performing a concurrent  drug  utilization  review ("DUR")
          analysis  and  alerting the  pharmacist  to possible  drug
          interactions   or  other   indications  of   inappropriate
          prescription drug usage

     o    updating the member's prescription drug claim record

     o    if the claim is accepted, confirming to the pharmacy that it will
          receive payment for the drug dispensed


     Mail  Pharmacy.  We integrate  our retail  pharmacy  services with our mail
pharmacy services. We operate five mail pharmacies, located in Maryland Heights,
Missouri; Tempe, Arizona; Albuquerque, New Mexico; Bensalem,  Pennsylvania;  and
Troy, New York.  These  pharmacies  provide  members with  convenient  access to
maintenance  medications  and enable us and our  clients  to control  drug costs
through operating efficiencies and economies of scale. In addition,  through our
mail  service  pharmacies,  we are directly  involved  with the  prescriber  and
member,   and  are  generally   able  to  achieve  a  higher  level  of  generic
substitutions  and therapeutic  interventions  than can be achieved  through the
retail pharmacy networks. This further reduces our clients' costs.

     Benefit Plan Design and Consultation.  We offer  consultation and financial
modeling to assist the client in  selecting a benefit plan design that meets its
needs for member  satisfaction and cost control.  The most common benefit design
options we offer to our clients are:

     o    financial incentives and reimbursement limitations on the drugs
          covered by the plan,  including  drug  formularies, flat dollar or
          percentage of prescription cost copayments, deductibles or annual
          benefit maximum

     o    generic drug substitution incentives


     o    incentives or requirements to use only network  pharmacies or to order
          certain drugs only by mail


     o    reimbursement  limitations on the number of days' supply of a drug
          that can be obtained

The selected  benefit  design is entered into our electronic  claims  processing
system,  which  applies the plan design  parameters  as claims are submitted and
enables us and our clients to monitor the financial performance of the plan.

     Advanced Formulary  Compliance and Therapy Management.  We provide advanced
formulary compliance services to our clients. Formularies are lists of drugs for
which coverage is provided under the  applicable  plan.  They are widely used in
managed health care plans and,  increasingly,  by other health plan managers. We
administer a number of different formularies for our clients that often identify
preferred  drugs whose use is encouraged  or required  through  various  benefit
design  features.  Historically,  many clients have selected a plan design which
includes  an open  formulary  in which  all drugs  are  covered  by the plan and
preferred drugs, if any, are merely  recommended.  More advanced options consist
of restricted formularies,  in which various financial or other incentives exist
for the selection of preferred drugs over their non-preferred  counterparts,  or
closed formularies, in which benefits are available only for drugs listed on the
formulary. Formulary preferences can be encouraged:

     o    by restricting the formulary through plan design features,such as
          tiered copayments, which require the member to pay a higher amount for
          a non-preferred drug

     o    through prescriber education programs,  in which we or the managed
          care  client   actively   seek  to  educate  the prescribers about the
          formulary preferences

     o    through our  OptiMedSM  drug therapy  management  program,
          which   actively   promotes    therapeutic   and   generic
          interchanges to reduce drug costs

We also offer the ExpressTherapeutics(R) program, an innovative proprietary drug
utilization  review and  clinical  intervention  program,  to assist  clients in
managing   compliance  with  the  prescribed  drug  therapy  and   inappropriate
prescribing   practices.   Although   we   derive   substantial   revenue   from
pharmaceutical manufacturers,  we recognize our primary responsibility is to the
plan   sponsors,   and  we  believe  our  contracts   with  the   pharmaceutical
manufacturers  provide  us the  flexibility  to  utilize  the  most  efficacious
products.


     Our National Pharmacy and Therapeutics  Committee,  composed of independent
physicians and pharmacists,  evaluates drugs within a therapy class to determine
whether it is clinically  appropriate to give  formulary  preference to one drug
over another.  If clinical  appropriateness  is established  to the  committee's
satisfaction,  it then evaluates the  cost-effectiveness of drugs in the therapy
class. Once a client adopts a formulary, we administer the formulary through our
electronic  claims  processing  system,  which  alerts  the  pharmacist  if  the
prescriber has not prescribed the preferred  drug. We or the pharmacist can then
contact the prescriber to attempt to obtain the  prescriber's  consent to switch
the prescription to the preferred product.

     Information Reporting and Analysis and Disease Management Programs. Through
the  development  of  increasingly   sophisticated  management  information  and
reporting  systems,  we  believe  we  manage  prescription  drug  benefits  more
effectively.  We have  developed  various  services  to offer our  clients.  One
service  enables a client to analyze  prescription  drug data to  identify  cost
trends and budget for expected  drug costs,  to assess the  financial  impact of
plan design  changes  and to identify  costly  utilization  patterns  through an
on-line  prescription  drug  decision  support tool called  RxWorkbenchTM.  This
service  permits  our  clients'  medically  sophisticated  personnel,  such as a
clinical  pharmacist  employed  by an HMO,  to  analyze  prescription  drug data
on-line.


     In  addition,  our  PPS  subsidiary  offers  provider  profiling,   disease
management  support  services  and  outcomes  assessments,   and  has  developed
proprietary  software  to process and sort  medical  claims,  prescription  drug
claims  and  clinical  laboratory  data.  This  data  is then  used  to  produce
comprehensive  information  about  treatment  of  patients  that  can be used by
managed care organizations and other companies involved in formulary  management
programs to treat a particular disease in a quality,  cost-effective manner. The
patient-specific  data  generated  through  all of  these  services  can then be
compared  to data in  PPS's  normative  databases,  and  PPS can  determine  the
effectiveness  of treatment  and  calculate  the total costs of that  treatment,
including the  prescription  drug  component,  resulting in an assessment of the
particular  outcome for a given  patient.  The  information  can also be used to
analyze the  practice  patterns of health care  providers  and create a provider
profile,  then  develop  empirically  based  "best  practice"  protocols,  which
recommend treatment regimens for specific diseases.

     We offer additional  disease  management  programs to assist health benefit
plans in managing the total health care costs associated with certain  diseases,
such as asthma,  diabetes and cardiovascular  disease.  These disease management
programs  are based upon the premise  that  patient and  provider  behavior  can
positively  influence medical outcomes and reduce overall medical costs. Patient
identification   can  be   accomplished   through   claims   data   analysis  or
self-enrollment,  and risk  stratification  surveys are conducted to establish a
plan of care for individual program participants. Patient education is primarily
effected  through a series of telephone and written  communications  with nurses
and  pharmacists,  and both providers and patients receive progress reports on a
regular basis. Outcome surveys are conducted and results are compiled to analyze
the clinical, personal and economic impact of the program.


     Electronic  Claims  Processing  System.  Our electronic  claims  processing
system enables us to implement sophisticated  intervention programs to assist in
managing  prescription  drug  utilization.  The  system can be used to alert the
pharmacist to generic  substitution and therapeutic  intervention  opportunities
and formulary  compliance  issues,  or to  administer  prior  authorization  and
step-therapy  protocol programs at the time a claim is submitted for processing.
Our  claims  processing  system  also  creates a  database  of drug  utilization
information  that can be accessed both at the time the prescription is dispensed
and also on a retrospective  basis to analyze utilization trends and prescribing
patterns for more intensive management of the drug benefit.


     Informed  Decision  Counseling.  We offer health care  decision  counseling
services  through our Express  Health  LineSM  division.  This service  allows a
member to call a  toll-free  telephone  number and  discuss a health care matter
with a care counselor who utilizes on-line decision support  protocols and other
guidelines  to provide  information  to assist the member in making an  informed
decision in seeking appropriate  treatment.  Records of each call are maintained
on-line  for  future  reference.  The  service  is  available  24  hours  a day.
Multilingual  capabilities  and  service  for  the  hearing  impaired  are  also
available.  The counselors  provide follow-up service to members to determine if
their  situation  was  resolved  or if  the  counselor  may  provide  additional
assistance.  Member satisfaction and outcomes  assessments are tracked through a
combination of member surveys, a quality assurance plan and system reports.

     Internet Pharmacy.  On March 29, 1999, we announced our plans to launch two
internet sites, YourPharmacy.com and DrugDigest.org. YourPharmacy.com will serve
as an online  drug  store,  and offer  both  prescription  and  over-the-counter
medications,  vitamins,  herbs and health and beauty aids.  DrugDigest.org  will
provide fact-based information on a variety of medications,  vitamins and herbs.
Both sites are  expected to be  operational  during the second  quarter of 1999.
Although both sites will be available to anyone,  we expect to capitalize on the
use of the sites by our existing membership base.

Non-PBM


     In addition to PBM services,  we also provide  non-PBM  services  including
outpatient  infusion  therapy,  specialty  distribution  and vision  care to our
clients.  During  1998,  2.1% of our net  revenues  were  derived  from  non-PBM
services,  compared to 3.2% and 3.9% during  1997 and 1996,  respectively.  This
decline is partially  due to the  acquisition  of ValueRx,  which  significantly
increased the Company's PBM service revenues.


     Outpatient  Infusion  Therapy - IVTx. We provide  infusion therapy services
which involve the  administration of prescription  drugs and other products to a
patient by  catheter,  feeding tube or  intravenously,  through our wholly owned
subsidiary IVTx, Inc. IVTx's clients,  which include managed care organizations,
third-party  administrators,  insurance  companies,  case management  companies,
unions and  self-insured  employers,  benefit from outpatient  infusion  therapy
services  because  the length of  hospital  stays can be  reduced.  Rather  than
receiving  infusion  therapy  in a  hospital,  IVTx  provides  infusion  therapy
services to  patients at home,  in a  physician's  office or in a  free-standing
center operated by a managed care  organization  or other entity.  IVTx provides
antimicrobial,     cardiovascular,    hematologic,    nutritional,    analgesic,
chemotherapeutic,   hydration,   endocrine,   respiratory  and  AIDS  management
treatments to patients.  IVTx  generally  prepares the  treatments in one of its
infusion  therapy  pharmacies,  which  are  licensed  independently  of our mail
pharmacies.  The treatments  are either  administered  under the  supervision of
IVTx's staff of registered nurses or licensed vocational nurses who are employed
at one of the IVTx  sites or,  in areas  where  IVTx  does not have a  facility,
through  contracted  registered nurses employed or otherwise retained by nursing
agencies.  IVTx  may also  contract  with  physicians  to  provide  consultation
services to its sites and contract  for pharmacy  services for patients who live
in outlying areas.


     We have facilities  supporting our infusion therapy  operations in Houston,
Texas; Dallas, Texas; Columbia,  Maryland; Maryland Heights, Missouri; Columbia,
Missouri; Northvale, New Jersey; Tempe, Arizona; and West Chester, Pennsylvania.
IVTx's  information  system  maintains  patient profiles and documents doses and
supplies  dispensed,  and its drug  utilization  review  component  accesses our
prescription records for members receiving both infusion and oral drug therapies
to screen for drug interactions, incompatibilities and allergies.


     Specialty  Distribution.  We began offering specialty distribution services
during the fourth  quarter of 1997  through our Tempe,  Arizona  facility.  This
service  assists  pharmaceutical  manufacturers  with the  distribution  of, and
creation  of  a  database  of  information  for,   products   requiring  special
handling/packaging  or  products  targeted  to a specific  physician  or patient
population.

     Vision Care. Until September 1998, we offered a managed vision care program
through a network  of  approximately  9,000  vision  care  providers  consisting
primarily of optometrists and a smaller number of ophthalmologists.  In addition
to administering the network, we ground and edged lenses,  assembled  eyeglasses
and  distributed  eyeglasses  and contact  lenses  from our vision lab  formerly
located in Earth City, Missouri.


     We entered  into an  agreement,  effective  September  1,  1998,  with Cole
Managed Vision ("Cole"), a subsidiary of Cole National Corporation,  pursuant to
which Cole  provides  certain  vision  care  services  for our clients and their
members.  The  agreement  enables us to focus on our PBM  business  while  still
offering a vision care service to our members by transferring  certain functions
performed by our Express  Scripts  Vision  Corporation  to Cole. The Cole vision
program is offered to substantially all of our PBM clients, and we receive a fee
from Cole based on usage of the vision benefit by members.  In conjunction  with
the Cole  agreement,  we also  announced  plans to close the  operations  of our
wholly owned  subsidiary,  PhyNet,  Inc., a vision  program  management  service
organization.

Suppliers

     We maintain an extensive inventory in our mail pharmacies of brand name and
generic  pharmaceuticals.  If a drug is not in our  inventory,  we can generally
obtain it from a supplier  within one or two  business  days.  We  purchase  our
pharmaceuticals  either  directly  from  manufacturers  or through  wholesalers.
During 1998,  approximately  56.2% of our pharmaceutical  purchases were through
one  wholesaler,  most  of  which  were  brand  name  pharmaceuticals.   Generic
pharmaceuticals are generally purchased directly from manufacturers.  We believe
that   alternative   sources  of  supply  for  most   generic   and  brand  name
pharmaceuticals are readily available.

Clients

     We are a major  provider  of PBM  services to the  managed  care  industry,
including  several  large HMOs,  and the employer  industry,  both  directly and
through third-party administrators.  Currently, some of our largest managed care
clients  are Aetna U.S.  Healthcare,  Inc.  ("Aetna";  the plans we service  are
composed  primarily  of the  plans of the  former  NYLCare  Health  Plans,  Inc.
("NYLCare")  entity,  which was a wholly  owned  subsidiary  of New York  Life),
Coventry Corporation  ("Coventry"),  and Blue Cross Blue Shield of Massachusetts
(which should begin  service with us during the third quarter of 1999).  Some of
our  largest  employer  groups  include  the  State  of  New  York  Empire  Plan
Prescription  Drug Program  (through a  subcontracting  relationship  with CIGNA
HealthCare), and the State of Ohio Bureau of Workers' Compensation Fund. We also
market  our  PBM  services  through  preferred  provider  organizations,   group
purchasing organizations,  health insurers, third-party administrators of health
plans and union-sponsored benefit plans.

     We provide  PBM  services,  including  informed  decision  counseling,  and
non-PBM services,  including infusion therapy services, to HMOs owned or managed
by Aetna/NYLCare,  and provide PBM services to insurance plans  underwritten and
administered  by  Aetna/NYLCare.  Of our net revenues from PBM services in 1998,
4.8% was for services provided to members of HMOs owned or managed by NYLCare or
insurance policies administered by NYLCare while NYLCare was a subsidiary of New
York Life.  Of our net  revenues  for non-PBM  services  in 1998,  21.5% was for
services  provided to members of HMOs owned or managed by NYLCare and  insurance
policies  administered  by NYLCare  while  NYLCare was a subsidiary  of New York
Life. In connection  with Aetna's  purchase of NYLCare,  we and Aetna reached an
agreement to extend our PBM service agreements with HMOs, excluding the informed
decision  counseling  component,  and our infusion  therapy  agreements  through
December 31, 2003,  with new pricing to take effect after December 31, 1999. The
informed  decision  counseling  and vision care (through our alliance with Cole)
agreements will continue  through  December 31, 1999. We also expect to continue
to provide PBM services to members of the NYLCare indemnity  programs until such
members are converted to Aetna  policies,  which is  anticipated to occur during
1999.  See Item 7 herein  and see  Note 4 of  Notes  to  Consolidated  Financial
Statements in Item 8 herein for additional discussion concerning Aetna/NYLCare.


     Upon completion of our pending  acquisition of DPS (assuming all conditions
necessary for the consummation  are satisfied),  United  HealthCare  Corporation
will become our largest client,  with  approximately 10 million  members.  DPS's
contract  with  United  HealthCare  will  expire  on May 31,  2000,  and  United
HealthCare has indicated it will be moving to another  provider at that time. In
our financial  analysis of the DPS  acquisition,  we assumed  United  HealthCare
would not renew its contract. However, if we are unable to reduce our costs on a
basis commensurate with our expectations and manage the transition of this large
client to another provider both efficiently and effectively,  the termination of
this  contract  may  materially  adversely  affect our  business  and results of
operations.


Acquisitions and Strategic Alliances


     On  February  9, 1999,  we  announced  that we had  executed  a  definitive
agreement  to acquire DPS from  SmithKline  Beecham  Corporation  and one of its
affiliates  for $700  million in cash.  We expect to  complete  the  acquisition
during the second  quarter of 1999.  We intend to finance  the  acquisition  and
refinance  all of our  existing  indebtedness  through  a $1.05  billion  credit
facility and a $150 million senior subordinated bridge credit facility. Goodwill
and  customer  contract  amortization  from  the  DPS  acquisition  will  be tax
deductible.  Upon  completion of our  acquisition of DPS, we will continue to be
the third  largest  PBM in North  America in terms of total  members and we will
have one of the largest managed care  membership  bases of any PBM. In addition,
the acquisition will provide us with enhanced clinical capabilities, systems and
technologies.  Consummation of the  transaction is subject to customary  closing
conditions, and we cannot provide any assurance that all such conditions will be
satisfied such that the transaction may be consummated as planned.


     On April 1, 1998,  we acquired  the PBM business  known as  "ValueRx"  from
Columbia/HCA  Healthcare  Corporation  for  approximately  $460  million in cash
(including   approximately  $15  million  in  transaction  costs  and  executive
severance costs). Historically, while both we and ValueRx served all segments of
the PBM market,  we primarily  focused on managed  care and smaller  self-funded
plan sponsors,  and ValueRx  concentrated on health insurance carriers and large
employer and union groups.  We believe the ValueRx  acquisition has provided and
will continue to provide us with additional resources and expertise,  which will
allow us to better  serve our clients and  competitively  pursue new business in
all segments of the PBM market.

     In January  1996,  we acquired the pharmacy  claim  processing  business of
Eclipse Claims  Services,  Inc., one of the largest  processors of  prescription
drug claims in Canada.  In  connection  with this  acquisition,  we entered into
five-year  exclusive  contracts  to  provide  PBM  services  in  Canada  to both
Prudential Insurance Company of America's Canadian Operations ("Prudential") and
Aetna Life Insurance Company of Canada ("Aetna").  The assets of Prudential were
previously  acquired by London Life Insurance Company ("London Life"), with whom
we  reached  an  agreement  whereby we would be the  exclusive  provider  of PBM
services to London Life.  In late 1997,  London Life was acquired by  Great-West
Lifeco.  Inc.  ("Great-West"),  who  receives  PBM  services  from  one  of  our
competitors  in Canada.  Great-West  decided not to continue using our services,
and we have  agreed to  transition  their  business  to  another  provider.  The
transition should be substantially  completed during the second or third quarter
of 1999.


     On December 31, 1995, we entered into a series of agreements  with American
HealthCare  Systems Purchasing  Partners,  L.P. (now known as Premier Purchasing
Partners,  L.P.;  the  "Premier  Partnership"),  a health care group  purchasing
organization  affiliated with APS Healthcare,  Inc. (now known as Premier, Inc.;
"Premier").  Premier is the largest  voluntary health care alliance in the U.S.,
formed as a result of the mergers in late 1995 of three  predecessor  alliances,
American HealthCare Systems, Premier Health Alliance and SunHealth Alliance. The
Premier alliance includes  approximately 215 integrated health care systems that
own or operate  approximately  800  hospitals  and are  affiliated  with another
approximately 900 hospitals.  Among other things, the agreements designate us as
Premier's   exclusive   preferred   provider  of  outpatient   PBM  services  to
shareholders  of Premier and their  affiliated  health care entities,  plans and
facilities which participate in the Partnership's  purchasing programs. The term
of the agreement is ten years,  subject to early  termination by the Partnership
at five years,  upon payment of an early termination fee to us. To terminate the
agreement at the end of the fifth year,  notice of termination  must be given to
us no later than March 31, 2000. The  termination  fee will then be equal to the
unamortized portion of the advance discount, calculated as of the effective date
of termination,  attributable to the issuance of our Class A Common Stock to the
Premier  Partnership for all issuances other than the initial issuance of shares
(the May, 1996 issuance  discussed below).  Assuming no additional  issuances of
our Class A Common Stock to the Premier Partnership,  if the Premier Partnership
notifies us on or before  March 31, 2000 of their  intention  to  terminate  the
agreements effective December 31, 2000, no termination fee will be due.

     Under the terms of our agreements, Premier is required to promote us as its
preferred PBM provider.  An individual Premier member or affiliated managed care
plan is not required to enter into an agreement  with us, but if it does so, the
term of the  agreement  would be for five  years.  We now  provide  service to a
number of Premier affiliates.  In May 1996, as a result of the number of Premier
plan members  receiving  our PBM services and the outcome of certain  joint drug
purchasing initiatives,  we issued 454,546 shares of our Class A Common Stock to
the  Premier  Partnership.  The Premier  Partnership  could  become  entitled to
receive  up to an  additional  4,500,000  shares  of our  Class A Common  Stock,
depending  upon the number of members in  Premier-affiliated  managed care plans
that  contract for our PBM services.  A  calculation  is made on April 1 of each
year to determine if a stock issuance will be made.  Although final calculations
for the April 1, 1999  measurement are not yet complete,  we do not believe that
the  calculation  will  result in an  additional  stock  issuance to the Premier
Partnership.  If the Premier  Partnership  earns stock  totaling  over 5% of our
total voting stock,  it is entitled to have its designee  nominated for election
to our  Board of  Directors.  As of  March  1,  1999,  the  Premier  Partnership
possessed  approximately  1.4% of the total equity  interests and  approximately
0.3% of the total voting power of our stock. See Note 3 of Notes to Consolidated
Financial  Statements  in Item 8 herein  for  additional  discussion  concerning
Premier.


     In November  1995, we entered into a ten-year  strategic  alliance with The
Manufacturers  Life Insurance Company  ("Manulife") one of the largest providers
of group  health  insurance  policies  in Canada,  pursuant  to which we are the
exclusive  provider of PBM services to Manulife.  As a result of this  alliance,
Manulife  can earn up to  approximately  474,000  shares  of our  Class A Common
Stock,  depending on its achievement of certain pharmacy claim volumes from 1996
to 2000.  To date,  we have not issued any shares to Manulife.  In addition,  if
Manulife  does not  terminate  the  alliance  in either year 6 or year 10 of the
agreement,  in each of such years it will  receive a warrant to  purchase  up to
237,000  shares of our Class A Common Stock  exercisable at 85% of the then fair
market value of such shares. The actual number of shares will depend upon claims
volume in such years. See Note 3 of Notes to Consolidated  Financial  Statements
in Item 8 herein for additional discussion concerning Manulife.

     In January  1995,  we entered  into an  exclusive  three-year  agreement to
provide  PBM  services  to  Coventry  Corporation,  pursuant  to which  Coventry
received 50,000 shares of our Class A Common Stock.  In December 1997,  Coventry
extended its  agreement  for an additional  two years.  In connection  with such
extension,  we issued, as an advance discount,  a seven-year warrant to purchase
an additional 50,000 shares of our Class A Common Stock,  exercisable at a price
of  $26.4544  per  share  (90% of the per  share  market  value  at the  time of
renewal).

Company Operations

     General. In our various facilities in the United States, we own and operate
five mail  pharmacies  and five member  service/pharmacy  help desk call centers
(four of  which  are  linked  to  create a  virtual  call  center  environment).
Electronic  pharmacy  claims  processing  is  principally  directed  through our
Maryland  Heights,  Missouri  facility then routed to the  appropriate  computer
platform at our  Maryland  Heights,  Missouri or Tempe,  Arizona  facility or at
facilities  operated by Perot Systems,  which maintains  certain of our computer
hardware.  At our  Canadian  facility,  we  have  sales  and  marketing,  client
services,   pharmacy  help  desk,  clinical,   provider  relations  and  certain
management information systems capabilities.

     Sales and  Marketing;  Client  Service.  We market our PBM  services in the
United  States  primarily  through  an  internal  staff  of  regional  marketing
representatives  and sales  personnel  located in various cities  throughout the
United States. The marketing  representatives are supported by a staff of client
service  representatives.  Our sales and marketing  personnel and client service
representatives  are organized by type of business  served  (i.e.,  managed care
group,  employer  group,  etc.).  Marketing  in Canada is conducted by marketing
representatives  located  in  Mississauga,  Ontario,  who  are  assisted  by our
personnel  based in the United States.  Although we cross-sell our IVTx services
to our PBM clients,  IVTx employs its own sales and marketing and client service
personnel to take advantage of individual market opportunities.

     Member  Services.  We believe client  satisfaction is dependent upon member
satisfaction.  Members  can  call  us  toll-free,  24  hours  a day,  to  obtain
information  about  their  prescription  drug  plan.  We employ  member  service
representatives who are trained to respond to member inquiries.

     Provider  Relations.  Our  Provider  Relations  group  is  responsible  for
contracting  and  administering  our pharmacy  networks.  To  participate in our
retail pharmacy networks,  pharmacists must meet certain  qualifications and are
periodically  required to represent to us that their  applicable state licensing
requirements are being maintained and that they are in good standing. Pharmacies
can contact our  various  pharmacy  help desks  toll-free,  24 hours a day,  for
information and assistance in filling  prescriptions  for members.  In addition,
our Provider  Relations group audits selected  pharmacies in the retail pharmacy
networks to determine  compliance  with the terms of the contract with us or our
clients.

     Clinical  Support.   Our  Health  Management  Services  Department  employs
clinical  pharmacists,  data  analysts  and  outcomes  researchers  who  provide
technical support for our PBM services.  These staff members assist in providing
high level  clinical  pharmacy  services  such as  formulary  development,  drug
information  programs,  clinical  interventions with physicians,  development of
drug therapy  guidelines and the evaluation of drugs for inclusion in clinically
sound  therapeutic   intervention   programs.  The  Health  Management  Services
Department also analyzes and prepares reports on clinical  pharmacy data for our
clients and conducts  specific data analyses to evaluate the  cost-effectiveness
of certain drug therapies.

     Information  Systems.  Our  Information  Systems  department  supports  our
pharmacy claims  processing  systems and other  management  information  systems
which are essential to our operations.  Uninterrupted  point-of-sale  electronic
retail pharmacy claims processing is a significant  operational  requirement for
us, and we are in the  process of  integrating  the  systems  acquired  with the
ValueRx acquisition with our historical systems located at our Maryland Heights,
Missouri and Tempe,  Arizona facilities.  Substantially all claims are presently
directed  through our Maryland  Heights,  Missouri  facility  then routed to the
appropriate  computer  platform  at our  Maryland  Heights,  Missouri  or Tempe,
Arizona  facility,  or at facilities  operated by Perot Systems  (Perot  Systems
maintains  the  computer  hardware  for the ValueRx  systems at its  facility in
Richardson,  Texas).  Our historical  claims  processing  systems located in our
Maryland  Heights,  Missouri and Tempe,  Arizona  facilities  are designed to be
redundant,  which enables us to do  substantially  all claims  processing in one
facility if the other facility is unable to process  claims.  Disaster  recovery
services  for  the  ValueRx  systems  are  provided  by a third  party.  We have
substantial capacity for growth in our claims processing facilities.

Competition


         We believe the primary  competitive  factors in each of our  businesses
are price, quality of service and breadth of available services.  We believe our
principal   competitive   advantages  are  our  size,  our   independence   from
pharmaceutical  manufacturer and drug store  ownership,  our strong managed care
and employer group customer base which supports the  development of advanced PBM
services and our commitment to provide  flexible and distinctive  service to our
clients. We believe our independence from pharmaceutical  manufacturer ownership
allows us to make unbiased formulary  recommendations to our clients,  balancing
both clinical  efficacy and cost, and our independence from drug store ownership
allows us to  construct  a  variety  or  convenient  and  cost-effective  retail
pharmacy  networks for our clients,  without  favoring any  particular  pharmacy
chain.  Some clients have indicated that this independence has been an important
factor in their decision making process.


     There are a large number of  companies  offering PBM services in the United
States.  Most of these companies are smaller than us and offer their services on
a local or  regional  basis.  We do,  however,  compete  with a number of large,
national companies,  including Merck-Medco Managed Care, L.L.C. (a subsidiary of
Merck & Co., Inc.), PCS, Inc. (a subsidiary of Rite-Aid  Corporation),  Caremark
International  Inc. (a subsidiary of MedPartners,  Inc.), and Advance  ParadigM,
Inc.,  as well as numerous  insurance  and Blue Cross and Blue Shield  plans and
certain  HMOs  which  have their own PBM  capabilities.  Several of these  other
companies may have greater financial, marketing and technological resources than
us.

     In  general,  consolidation  is a  critical  factor  in the  pharmaceutical
industry, and particularly so in the PBM segment.  Competitors that are owned by
pharmaceutical  manufacturers  or drug store chains may have pricing  advantages
that are  unavailable  to us and other  independent  PBMs.  However,  we believe
independence  from  pharmaceutical  manufacturer  and drug  store  ownership  is
important to certain clients,  and we believe this  independence  provides us an
advantage in marketing to those clients.

     On  February  9, 1999,  we  announced  that we had  executed  a  definitive
agreement to purchase DPS for $700 million. As more particularly discussed above
and in Item 7,  consummation of the transaction is subject to customary  closing
conditions, but is expected to occur during the second quarter of 1999.

     Some of our PBM services,  such as disease  management  services,  informed
decision  counseling  services  and  medical  information  management  services,
compete with those being offered by  pharmaceutical  manufacturers,  other PBMs,
large  national  companies,   specialized   disease  management   companies  and
information  service  providers.  Our non-PBM  services compete with a number of
large national companies as well as with local providers.

Government Regulation

     Various  aspects of our  businesses  are governed by federal and state laws
and  regulations.  Since  sanctions may be imposed for violations of these laws,
compliance  is a  significant  operational  requirement.  We  believe  we are in
substantial  compliance  with all existing  legal  requirements  material to the
operation  of our  businesses.  There are,  however,  significant  uncertainties
involving the  application of many of these legal  requirements to our business.
In addition, there are numerous proposed health care laws and regulations at the
federal and state levels, many of which could adversely affect our business.  We
are unable to predict what additional federal or state legislation or regulatory
initiatives  may be enacted in the future relating to our business or the health
care industry in general,  or what effect any such  legislation  or  regulations
might  have on us.  We  cannot  provide  any  assurance  that  federal  or state
governments will not impose additional  restrictions or adopt interpretations of
existing  laws that could  have a material  adverse  affect on our  business  or
financial position.

     Pharmacy  Benefit  Management  Regulation  Generally.  Certain  federal and
related  state  laws and  regulations  affect or may  affect  aspects of our PBM
business. Among these are the following:

     FDA Regulation. The U.S. Food and Drug Administration ("FDA") generally has
authority to regulate drug promotional materials that are disseminated "by or on
behalf of" a drug  manufacturer.  In January,  1998, the FDA issued a Notice and
Draft  Guidance  regarding  its intent to regulate  certain drug  promotion  and
switching activities of pharmacy benefit managers that are controlled,  directly
or indirectly, by drug manufacturers. The position taken by the FDA in the Draft
Guidance  was  that  promotional  materials  used by an  independent  PBM may be
subject to FDA regulation depending upon the circumstances, including the nature
of the relationship between the PBM and the manufacturer. We, along with various
other parties, submitted written comments to the FDA regarding the basis for FDA
regulation of PBM activities.  It was our position that,  while the FDA may have
jurisdiction to regulate drug manufacturers,  the Draft Guidance went beyond the
FDA's  jurisdiction.   After  extending  the  comment  period  due  to  numerous
objections  to the  proposed  Draft,  the FDA  essentially  withdrew  the  Draft
Guidance in the fall of 1998,  stating  that it would  reconsider  the basis for
such a Guidance.  The FDA has not addressed the issue since the  withdrawal  and
has  not  indicated  when or even if it will  continue  to  address  the  issue.
However, there can be no assurance that the FDA will not again attempt to assert
jurisdiction over certain aspects of our PBM business in the future and, in such
event, the impact could materially adversely affect our operations.


     Anti-Remuneration/Fraud  and Abuse Laws. Federal law prohibits, among other
things,  an entity from paying or receiving,  subject to certain  exceptions and
"safe harbors," any  remuneration to induce the referral of individuals  covered
by federally  funded  health care  programs,  including  Medicare,  Medicaid and
CHAMPUS or the purchase (or the arranging for or  recommending  of the purchase)
of items or services  for which  payment may be made under  Medicare,  Medicaid,
CHAMPUS or other federally-funded health care programs. Several states also have
similar  laws that are not  limited to services  for which  Medicare or Medicaid
payment may be made. State laws vary and have been  infrequently  interpreted by
courts or regulatory  agencies.  Sanctions for violating these federal and state
anti-remuneration  laws may include imprisonment,  criminal and civil fines, and
exclusion from participation in the Medicare and Medicaid programs.


     The federal statute has been interpreted  broadly by courts,  the Office of
Inspector  General  (OIG)  within the  Department  of Health and Human  Services
(HHS), and administrative  bodies. Because of the federal statute's broad scope,
federal  regulations  establish  certain  "safe  harbors" from  liability.  Safe
harbors exist for certain  properly  reported  discounts  received from vendors,
certain  investment  interests,  and certain properly disclosed payments made by
vendors  to group  purchasing  organizations.  HHS has  previously  announced  a
proposed   safe  harbor  that  would  protect   certain   discount  and  payment
arrangements between PBMs and HMO risk contractors serving Medicaid and Medicare
members,  and an  interim  final rule is  currently  being  developed  by HHS. A
practice  that does not fall within a safe harbor is not  necessarily  unlawful,
but may be subject to scrutiny and  challenge.  In the absence of an  applicable
exception or safe harbor,  a violation of the statute may occur even if only one
purpose of a payment  arrangement is to induce  patient  referrals or purchases.
Among the practices that have been identified by the OIG as potentially improper
under the statute are certain  "product  conversion  programs" in which benefits
are given by drug  manufacturers  to  pharmacists  or physicians  for changing a
prescription  (or  recommending  or  requesting  such a change) from one drug to
another. Such laws have been cited as a partial basis, along with state consumer
protection laws discussed below, for investigations and multi-state  settlements
relating  to  financial  incentives  provided  by drug  manufacturers  to retail
pharmacies in connection with such programs.

     To our  knowledge,  these  anti-remuneration  laws have not been applied to
prohibit PBMs from receiving amounts from drug  manufacturers in connection with
drug purchasing and formulary management programs,  to therapeutic  intervention
programs conducted by independent PBMs, or to the contractual relationships such
as  those  we have  with  certain  of our  clients.  We  believe  that we are in
substantial  compliance  with the legal  requirements  imposed  by such laws and
regulations,  and  we  believe  that  there  are  material  differences  between
drug-switching  programs  that have been  challenged  under  these  laws and the
programs we offer to our clients.  However,  there can be no  assurance  that we
will not be subject to scrutiny or challenge under such laws or regulations. Any
such challenge could have a material adverse effect on us.

     ERISA  Regulation.  The  Employee  Retirement  Income  Security Act of 1974
("ERISA")  regulates  certain  aspects of employee  pension  and health  benefit
plans,   including  self-funded  corporate  health  plans  with  which  we  have
agreements to provide PBM services.  We believe that the conduct of our business
is not  subject  to the  fiduciary  obligations  of  ERISA,  but there can be no
assurance that the U.S.  Department of Labor,  which is the agency that enforces
ERISA,  would not assert that the fiduciary  obligations  imposed by the statute
apply to certain aspects of our operations.

     In addition to its fiduciary  provisions,  ERISA imposes civil and criminal
liability  on service  providers to health  plans and certain  other  persons if
certain forms of illegal remuneration are made or received.  These provisions of
ERISA are  similar,  but not  identical,  to the health  care  anti-remuneration
statutes discussed in the immediately  preceding section;  in particular,  ERISA
lacks the statutory and regulatory "safe harbor"  exceptions  incorporated  into
the health  care  statute.  Like the health  care  anti-remuneration  laws,  the
corresponding  provisions of ERISA are broadly written and their  application to
particular cases is often uncertain. We have implemented policies, which include
disclosure to health plan sponsors  with respect to any  commissions  paid by us
that might fall within the scope of such provisions,  and accordingly believe we
are in substantial  compliance with these provisions of ERISA.  However,  we can
provide no  assurance  that our  policies in this  regard  would be found by the
appropriate enforcement authorities to meet the requirements of the statute.

     Proposed Changes in Canadian  Healthcare  System. In Canada, the provincial
health plans  provide  universal  coverage for basic health care  services,  but
prescription  drug coverage under the government  plans is provided only for the
elderly  and the  indigent.  In late  1997,  a  proposal  was made by a  federal
government  health care task force to include  coverage for  prescription  drugs
under the provincial  health insurance  plans,  which report was endorsed by the
federal  government's  Health Minister.  This report was advisory in nature, and
not  binding  upon the  federal  or  provincial  governments.  We  believe  this
initiative  is dormant at the present  time,  and we are unable to determine the
likelihood of adoption of the proposal in the future.

     Numerous  state  laws  and  regulations  also  affect  aspects  of our  PBM
business. Among these are the following:

     Comprehensive  PBM  Regulation.  Although  no state has passed  legislation
regulating PBM activities in a comprehensive  manner,  such legislation has been
introduced  in the past in  California  and  Virginia,  and bills were  recently
proposed in Texas and Colorado. Such legislation, if enacted in a state in which
we have a significant  concentration  of business,  could  adversely  impact our
operations.

     Consumer  Protection  Laws. Most states have consumer  protection laws that
have been the basis for investigations and multi-state  settlements  relating to
financial  incentives  provided by drug  manufacturers  to retail  pharmacies in
connection with drug switching programs.  In addition,  pursuant to a settlement
agreement  entered into with seventeen  states on October 25, 1995,  Merck-Medco
Managed Care, LLC ("Medco"),  the PBM subsidiary of pharmaceutical  manufacturer
Merck & Co.,  agreed to have  pharmacists  affiliated  with Medco  mail  service
pharmacies  disclose to  physicians  and  patients the  financial  relationships
between  Merck,  Medco,  and the mail  service  pharmacy  when such  pharmacists
contact physicians seeking to change a prescription from one drug to another. We
believe that our contractual  relationships  with drug  manufacturers and retail
pharmacies  do  not  include  the  features  that  were  viewed  by  enforcement
authorities as problematic in these settlement agreements. However, no assurance
can be given that we will not be subject to scrutiny or  challenge  under one or
more of these laws.

     Network  Access  Legislation.  A  majority  of states now have some form of
legislation affecting our ability to limit access to a pharmacy provider network
or from  removing  network  providers.  Such  legislation  may require us or our
client to admit any retail  pharmacy  willing to meet the plan's price and other
terms for network  participation  ("any willing provider"  legislation);  or may
provide that a provider may not be removed from a network  except in  compliance
with certain procedures ("due process" legislation). We have not been materially
affected by these  statutes  because we maintain a large  network of over 52,000
retail   pharmacies  and  will  admit  any  licensed  pharmacy  that  meets  our
credentialling criteria,  involving such matters as adequate insurance coverage,
minimum  hours of  operation,  and the  absence of  disciplinary  actions by the
relevant state agencies.


     Legislation  Affecting  Plan Design.  Some states have enacted  legislation
that prohibits the plan sponsor from  implementing  certain  restrictive  design
features,  and many  states have  introduced  legislation  to  regulate  various
aspects of managed  care plans,  including  provisions  relating to the pharmacy
benefit.  For  example,   some  states,  under  so-called  "freedom  of  choice"
legislation, provide that members of the plan may not be required to use network
providers, but must instead be provided with benefits even if they choose to use
non-network  providers.  Other states have  enacted  legislation  purporting  to
prohibit health plans from offering members financial incentives for use of mail
service  pharmacies.  Legislation has been introduced in some states to prohibit
or restrict therapeutic intervention, or to require coverage of all FDA approved
drugs.  Other states mandate  coverage of certain  benefits or  conditions,  and
require  coverage  of  specific  drugs  if  deemed  medically  necessary  by the
prescribing  physician.  Such legislation does not generally apply to us, but it
may  apply to  certain  of our  clients  (HMOs  and  health  insurers).  If such
legislation  were to become widely adopted and broad in scope, it could have the
effect of limiting the economic  benefits  achievable  through  pharmacy benefit
management. This could have a material adverse effect on our business.


     Licensure Laws.  Many states have licensure or registration  laws governing
certain types of ancillary health care organizations,  including PPOs, TPAs, and
companies  that provide  utilization  review  services.  The scope of these laws
differs  significantly  from state to state, and the application of such laws to
the activities of pharmacy benefit managers often is unclear. We have registered
under such laws in those  states in which we have  concluded,  after  discussion
with the appropriate state agency, that such registration is required.

     Legislation Affecting Drug Prices. Some states have adopted so-called "most
favored nation" legislation providing that a pharmacy participating in the state
Medicaid  program  must give the state the best  price that the  pharmacy  makes
available to any third party plan.  Such  legislation  may adversely  affect our
ability to  negotiate  discounts in the future from  network  pharmacies.  Other
states have enacted  "unitary  pricing"  legislation,  which  mandates  that all
wholesale  purchasers  of drugs  within  the  state be given  access to the same
discounts and incentives.  Such  legislation has been introduced in the past but
not enacted in Missouri, Arizona,  Pennsylvania,  and New York, and is presently
being  considered  in New Mexico,  all states  where the Company  operates  mail
service  pharmacies.  Such  legislation,  if enacted in a state where one of our
mail  service  pharmacies  is  located,  could  adversely  affect our ability to
negotiate discounts on our purchase of prescription drugs to be dispensed by our
mail service pharmacies.

     Regulation of Financial Risk Plans. Fee-for-service prescription drug plans
are generally not subject to financial regulation by the states. However, if the
PBM  offers to  provide  prescription  drug  coverage  on a  capitated  basis or
otherwise  accepts  material  financial  risk in providing the benefit,  laws in
various  states may regulate  the plan.  Such laws may require that the party at
risk establish reserves or otherwise demonstrate financial responsibility.  Laws
that may apply in such cases include insurance laws, HMO laws or limited prepaid
health  service plan laws. In those cases in which we have contracts in which we
are  materially  at risk to provide  the  pharmacy  benefit,  we believe we have
complied with all applicable laws.

     Many of these  state  laws may be  preempted  in whole or in part by ERISA,
which provides for comprehensive  federal  regulation of employee benefit plans.
However,  the  scope  of  ERISA  preemption  is  uncertain  and  is  subject  to
conflicting  court  rulings,  and in any event we  provide  services  to certain
clients, such as governmental  entities,  that are not subject to the preemption
provisions  of ERISA.  Other state laws may be invalid in whole or in part as an
unconstitutional  attempt by a state to regulate  interstate  commerce,  but the
outcome of  challenges  to these laws on this basis is  uncertain.  Accordingly,
compliance  with  state  laws  and  regulations  is  a  significant  operational
requirement for us.

     Mail  Pharmacy  Regulation.  Our mail  service  pharmacies  are  located in
Arizona, Missouri, New Mexico, New York and Pennsylvania, and we are licensed to
do business  as a pharmacy in each such state.  Many of the states into which we
deliver pharmaceuticals have laws and regulations that require out-of-state mail
service pharmacies to register with, or be licensed by, the board of pharmacy or
similar  regulatory body in the state.  These states  generally  permit the mail
service  pharmacy to follow the laws of the state  within which the mail service
pharmacy  is  located,  although  one  state  also  requires  that we  employ  a
pharmacist  licensed  in that  state.  Another  state  has  proposed  a  similar
requirement.  We have registered in every state in which, to our knowledge, such
registration is required.

     One state has a statute that purports to prohibit  residents from obtaining
prescription  drugs by mail if the mail order business of the company dispensing
the drugs  represents  more than a specified  percentage of the company's  total
volume of pharmacy business.  The statute is ambiguous in certain respects,  but
we do not believe our mail order volume exceeds the threshold percentage. We are
licensed as a pharmacy in that state. No enforcement action has been taken under
the statute  against us, and to our  knowledge,  no such  enforcement  action is
contemplated.  Approximately  2.5% of our  revenues  come from mail  delivery of
prescription  drugs into that state.  If an  enforcement  action were  commenced
against  us under  that  statute,  we would  consider  all of our  alternatives,
including challenging the validity of the statute.

     Other statutes and regulations affect our mail service operations.  Federal
statutes  and  regulations  govern  the  labeling,  packaging,  advertising  and
adulteration of prescription drugs and the dispensing of controlled  substances.
The Federal Trade  Commission  requires mail order sellers of goods generally to
engage in truthful  advertising,  to stock a reasonable supply of the product to
be sold,  to fill mail orders within  thirty days,  and to provide  clients with
refunds  when  appropriate.  The United  States  Postal  Service  has  statutory
authority to restrict the  transmission of drugs and medicines  through the mail
to a degree that could have an adverse effect on our mail service operations.

     Regulation of Informed Decision Counseling and Disease Management Services.
Our health care decision support counseling and disease management  programs are
affected  by many of the same types of state laws and  regulations  as our other
activities.  In addition,  all states  regulate the practice of medicine and the
practice of  nursing.  We do not believe our  informed  decision  counseling  or
disease management  activities constitute either the practice of medicine or the
practice of nursing. However, there can be no assurance that a regulatory agency
in one or more states may not assert a contrary  position,  and we are not aware
of any controlling legal precedent for services of this kind.

     Privacy and Confidentiality Legislation. Most of our activities involve the
receipt  or use  of  confidential,  medical  information  concerning  individual
members.  In addition,  we use aggregated  and anonymized  data for research and
analysis  purposes.  Legislation  has been  proposed at the federal level and in
several  states to  restrict  the use and  disclosure  of  confidential  medical
information.  To date,  no such  legislation  has been  enacted  that  adversely
impacts our ability to provide our services,  but there can be no assurance that
federal or state governments will not enact legislation,  impose restrictions or
adopt interpretations of existing laws that could have a material adverse effect
on our operations.

     Non-PBM  Regulatory  Environment.  Our  non-PBM  activities  operate  in  a
regulatory environment that is quite similar to that of our PBM activities.


     Regulation of Infusion  Therapy  Services.  Our infusion  therapy  services
business  is subject to many of the same or similar  federal  and state laws and
regulations  affecting  our  pharmacy  benefit  management  business,  including
anti-remuneration,  physician self-referral, and other fraud and abuse type laws
and  regulations.  In addition,  some states  require that providers of infusion
therapy  services be  licensed.  We are  licensed  as a home  health  agency and
pharmacy in Texas, as a residential service agency and pharmacy in Maryland, and
as a pharmacy in New Jersey,  Missouri,  Arizona and  Pennsylvania.  We are also
licensed as a non-resident pharmacy in various states. We believe that we are in
substantial compliance with such licensing requirements.


     The  Joint  Commission  on   Accreditation   of  Healthcare   Organizations
("JCAHO"), a non-profit, private organization, has established written standards
for health care  organizations and home care services,  including  standards for
services  provided  by home  infusion  therapy  companies.  All of our  infusion
therapy facilities have received JCAHO accreditation,  which allows us to market
infusion  therapy services to Medicare and Medicaid  programs.  If we expand our
home  infusion  therapy  services  to other  states or to  Medicare  or Medicaid
programs,  we  may  be  required  to  comply  with  other  applicable  laws  and
regulations.

     Future  Regulation.  We are unable to predict  accurately  what  additional
federal or state  legislation  or regulatory  initiatives  may be enacted in the
future  relating to our  businesses or the health care  industry in general,  or
what effect any such  legislation or regulations  might have on us. There can be
no  assurance  that  federal or state  governments  will not  impose  additional
restrictions  or adopt  interpretations  of  existing  laws  that  could  have a
material adverse effect on our business or financial position.


Service Marks and Trademarks

     We  have   registered   the  service  marks  "Express   Scripts",   "PERx",
"ExpressComp",  "ExpressReview",   "ExpressTherapeutics",   "IVTx",  "PERxCare",
"PERxComp",  "RxWizard",  "PTE",  "ValueRx" and "Value Health,  Inc.",  with the
United  States  Patent and  Trademark  Office.  Our  rights to these  marks will
continue  so long as we comply  with the usage,  renewal  filing and other legal
requirements  relating to the renewal of service marks. We are in the process of
applying for  registration of several other  trademarks and service marks. If we
are unable to obtain any additional registrations,  we believe there would be no
material adverse effect on our business.


Insurance

     Our PBM operations,  including the dispensing of pharmaceutical products by
our mail service  pharmacies,  and the services  rendered in connection with our
disease management and informed decision  counseling  services,  and our non-PBM
operations,  such as the products and services  provided in connection  with our
infusion  therapy  programs  (including the associated  nursing  services),  may
subject  us to  litigation  and  liability  for  damages.  We  believe  that our
insurance protection is adequate for our present business operations,  but there
can be no  assurance  that we will be able  to  maintain  our  professional  and
general  liability  insurance  coverage  in the  future or that  such  insurance
coverage will be available on  acceptable  terms or adequate to cover any or all
potential  product or professional  liability  claims.  A successful  product or
professional  liability  claim in excess of our insurance  coverage,  or one for
which an exclusion from coverage  applies,  could have a material adverse effect
upon our financial position or results of operations.

Employees

     As of March 1, 1999, we employed a total of 3,283 employees in the U.S. and
71 employees in Canada.  Approximately 375 of the U.S.  employees are members of
collective  bargaining  units.  Specifically,  we employ  members of the Service
Employees International Union at our Bensalem, Pennsylvania facility, members of
the United Auto Workers Union at our Farmington Hills,  Michigan  facility,  and
members  of the  United  Food  and  Commercial  Workers  Union  ("UFCW")  at our
Albuquerque,  New Mexico facility.  One of our collective  bargaining agreements
with the UFCW expires on July 1, 1999. We have not begun  negotiations  with the
UFCW for this contract at this time.

Executive Officers of the Registrant

     Pursuant to General Instruction G(3) of the Annual Report on Form 10-K, the
information  regarding executive officers of the Company required by Item 401 of
Regulation S-K is hereby included in Part I of this report.

     The  executive  officers of the Company and their ages as of March 1, 1999,
are as follows:

          Name              Age             Position

  Howard L. Waltman           66    Chairman of the Board
  Barrett A. Toan             51    President, Chief Executive
                                    Officer and Director
  Stuart L. Bascomb           57    Executive Vice President
  Thomas M. Boudreau          47    Senior Vice President of
                                    Administration, General Counsel
                                    and Secretary
  Patrick J. Byrne            43    Senior Vice President Plymouth
                                    Site Operations
  Robert W. (Joe) Davis       52    Senior Vice President and Chief
                                    Information Systems Officer
  Linda L. Logsdon            51    Senior Vice President of Health
                                    Management Services
  David A. Lowenberg          49    Senior Vice President and
                                    Director of Site Operations
  George Paz                  43    Senior Vice President and Chief
                                    Financial Officer
  Jean-Marc Quach             40    Senior Vice President and Chief
                                    of Staff
  Kurt D. Blumenthal          54    Vice President of Finance
  Joseph W. Plum              51    Vice President and Chief
                                    Accounting Officer

     Mr. Waltman was elected Chairman of the Board of the Company in March 1992.
Mr.  Waltman has been a director of the Company since its inception in September
1986.  From  September  1992 to December 31,  1995,  Mr.  Waltman  served as the
Chairman  of the Board of NYLCare  Health  Plans,  Inc.,  which was an  indirect
wholly-owned subsidiary of New York Life Insurance Company at the time.

     Mr. Toan was elected  Chief  Executive  Officer in March 1992 and President
and a director in October 1990.  Mr. Toan has been an executive  employee of the
Company since May 1989.

     Mr.  Bascomb was elected  Executive  Vice President of the Company in March
1989, and also served as Chief  Financial  Officer and Treasurer from March 1992
until May 1996.

     Mr.  Boudreau  was  elected  Senior  Vice  President,  General  Counsel and
Secretary of the Company in October  1994.  He has served as General  Counsel of
the Company since June 1994.  From September 1984 until June 1994, Mr.  Boudreau
was a partner in the St. Louis law firm of Husch & Eppenberger.

     Mr. Byrne was elected  Senior Vice  President  Plymouth Site  Operations in
May,  1998.  From  April 1996  until  October  1997,  Mr.  Byrne  served as Vice
President of  Underwriting  for ValueRx,  and then served as Vice  President and
General  Manager  for the  National  Employer  Business  Unit of ValueRx for the
period November 1997 until May 1998. From 1991 until March 1996, Mr. Byrne was a
Director of Finance for United Healthcare Corporation.

     Mr. Davis was elected Senior Vice President and Chief  Information  Systems
Officer of the  Company in  September  1997.  Mr.  Davis  served as  Director of
Technical  Services and Computer  Operations of the Company from July 1993 until
July 1995, and as Vice President and General Manager of St. Louis  Operations of
the Company from July 1995 until September 1997.

     Ms. Logsdon was elected Senior Vice President of Health Management Services
in May, 1997, and served as Vice President of Demand and Disease Management from
November  1996 until that time.  Prior to joining the Company in November  1996,
Ms. Logsdon served as Vice President of Corporate  Services and Chief  Operating
Officer  of  United  HealthCare's  Midwest  Companies-GenCare/Physicians  Health
Plan/MetraHealth,  a  St.  Louis-based  health  maintenance  organization,  from
February 1995 to October 1996, and as Deputy Director/Vice  President of GenCare
Health Systems,  Inc., also a St. Louis-based  health maintenance  organization,
from June 1992 to February 1995.

     Mr.  Lowenberg  was elected  Senior  Vice  President  and  Director of Site
Operations of the Company in October,  1994 and Vice President of the Company in
November  1993.  Mr.  Lowenberg  also  served as  General  Manager  of the Tempe
facility from March 1993 until January 1995.

     Mr. Paz joined the Company and was elected  Senior Vice President and Chief
Financial  Officer in January 1998. Prior to joining the Company,  Mr. Paz was a
partner  in the  Chicago  office  of  Coopers & Lybrand  from  December  1995 to
December  1997,  and served as  Executive  Vice  President  and Chief  Financial
Officer of Life Partners  Group,  Inc., a life insurance  company,  from October
1993 until December 1995.

     Mr. Quach was elected Senior Vice President and Chief of Staff in May 1998.
Prior to joining the Company,  Mr. Quach was the Director of Marketing for Roche
Diagnostics  during the period  April 1996 to May 1998.  Mr. Quach served as the
Director of Pharmacy for NYLCare  Health  Plans,  Inc. for the period  September
1991 to April 1996,  which was an indirect  wholly-owned  subsidiary of New York
Life Insurance Company at the time.

     Mr.  Blumenthal  was elected  Vice  President  of Finance in May 1995,  and
served  as Acting  Chief  Financial  Officer  of the  Company  from July 1996 to
January 1998.  From August 1993 to February 1995, Mr.  Blumenthal  served as the
Chief Financial Officer of President Baking Co.

     Mr. Plum was elected Vice President in October 1994 and has served as Chief
Accounting Officer since March 1992 and Corporate Controller since March 1989.

Item 2 - Properties

     We operate our United States and Canadian PBM and non-PBM businesses out of
leased and owned facilities  throughout the United States and Canada. All of our
facilities are leased except for our Albuquerque,  New Mexico facility, which we
own.

             PBM Facilities                             Non-PBM Facilities
       Maryland Heights, Missouri                   Maryland Heights, Missouri
          Earth City, Missouri                          Columbia, Missouri
             Tempe, Arizona                               Dallas, Texas
          Plymouth, Minnesota                             Houston, Texas
         Bensalem, Pennsylvania                         Columbia, Maryland
             Troy, New York                               Tempe, Arizona
       Farmington Hills, Michigan                         Tempe, Arizona
        Albuquerque, New Mexico                     West Chester, Pennsylvania
          Mississauga, Ontario

     Our Maryland  Heights,  Missouri  facility  houses our  corporate  offices.
IVTx's  corporate  offices are also  located at our Maryland  Heights,  Missouri
facility.  The non-PBM specialty  distribution  services are operated out of our
facility in Tempe,  Arizona.  We believe our facilities have been generally well
maintained and are in good operating condition.  Our existing facilities contain
approximately 600,000 square feet in area, in the aggregate.

     During  1998,  we  entered  into an  operating  lease  for a new  corporate
headquarters  facility to be located adjacent to our existing  Maryland Heights,
Missouri facility, which will contain approximately 140,000 square feet in area.
The new  building is  presently  under  construction  and we  anticipate  taking
possession  during the second quarter of 1999. We are continuing to evaluate our
future requirements for additional space.

     We own computer systems for both the Maryland Heights,  Missouri and Tempe,
Arizona sites.  Computer systems to process the traditional ValueRx business are
located at Perot Systems' facility in Richardson, Texas. Perot Systems maintains
the computer  hardware on our behalf.  Our software for drug utilization  review
and other  products  has been  developed  internally  by us or  purchased  under
perpetual,  nonexclusive  license  agreements  with third parties.  Our computer
systems at each site are  extensively  integrated and share common files through
local and wide  area  networks.  An  uninterruptable  power  supply  and  diesel
generator allow our computers,  telephone systems and mail pharmacy at each site
to continue to function  during a power outage.  To protect against loss of data
and extended downtime, we store software and redundant files at both on-site and
off-site  facilities on a regular basis and have contingency  operation plans in
place.  We cannot,  however,  provide  any  assurance  that our  contingency  or
disaster recovery plans would adequately address all relevant issues.


Item 3 - Legal Proceedings


     As discussed in detail in our Quarterly  Report on Form 10-Q for the period
ended June 30, 1998, filed with the Securities and Exchange Commission on August
13, 1998 (the "Second Quarter 10-Q"), we acquired all of the outstanding capital
stock of Value  Health,  Inc.,  a  Delaware  corporation  ("VHI"),  and  Managed
Prescription  Network,  Inc.,  a  Delaware  corporation  ("MPN")  from  Columbia
HCA/HealthCare Corporation ("Columbia") and its affiliates on April 1, 1998 (the
"Acquisition").  VHI, MPN and/or their subsidiaries (collectively, the "Acquired
Entities"), were party to various legal proceedings, investigations or claims at
the time of the Acquisition. The effect of these actions on our future financial
results is not subject to reasonable estimation because considerable uncertainty
exists  about the  outcomes.  Nevertheless,  in the opinion of  management,  the
ultimate liabilities resulting from any such lawsuits,  investigations or claims
now pending should not materially  affect our consolidated  financial  position,
results of operations or cash flows. A brief  description of the most notable of
the proceedings follows:

              Bash,  et al.  v.  Value  Health,  Inc.,  et al.,  No.  3:97cv2711
         (JCH)(D.Conn.)  ("Bash"). On December 15, 1995, a purported shareholder
         class action  lawsuit was filed by Irwin Bash and Leykin,  Hyman & Bash
         Associates in the United States  District Court for the District of New
         Mexico against  Diagnostek,  Inc.  ("Diagnostek"),  Nunzio P. DeSantis,
         William Baron, and Courtland Miller (all former  Diagnostek  officers).
         Also  named  as  defendants  in Bash are  Value  Health,  Inc.  ("Value
         Health"),  Robert E.  Patricelli,  William  J.  McBride  and  Steven J.
         Shulman (certain of Value Health's former officers). The Bash Complaint
         asserts that Value Health and certain  other  defendants  made false or
         misleading  statements to the public in connection  with Value Health's
         acquisition of Diagnostek in 1995.  The Bash  Complaint  asserts claims
         under the  Securities  Act of 1933 and the  Securities  Exchange Act of
         1934, as well as common law claims, and seeks  certification of a class
         consisting of all persons (with  certain  exclusions)  who purchased or
         otherwise  acquired  (a)  Diagnostek  common  stock from March 27, 1994
         through July 28,  1995;  (b) Value  Health  common stock  pursuant to a
         Proxy and Prospectus and merger in which their  Diagnostek  shares were
         converted into Value Health  shares;  and (c) Value Health common stock
         from March 27, 1995 through  November 7, 1995.  The Bash Complaint does
         not specify the amount of damages sought. On March 26, 1996, the former
         Diagnostek officers filed a motion seeking either dismissal of the case
         or a transfer to the District of Connecticut,  where the  earlier-filed
         Freedman action  (discussed  below) was pending.  In the late summer of
         1997, the Bash plaintiffs filed an Amended Complaint that deleted those
         allegations  that  overlapped  with  the  allegations  contained  in an
         earlier  lawsuit  filed  against  Diagnostek  and certain of its former
         officers.  A formal  order  approving  the  settlement  of this earlier
         lawsuit  was  entered  by the  United  States  District  Court  for the
         District of New Mexico on November  21, 1997.  In addition,  defendants
         filed a renewed  motion to  transfer  the  action  to  Connecticut.  On
         October  24,  1997,  an answer  was  filed on  behalf of Value  Health,
         Diagnostek,  and the former  directors and officers of Value Health who
         had been named as  defendants.  On November  28,  1997,  the New Mexico
         court  entered  an order  transferring  the action to  Connecticut.  On
         February 4, 1998,  the court  ordered that  plaintiffs  in the Freedman
         action,   discussed  below,  share  all  discovery  obtained  from  the
         defendants  and third parties in their  lawsuit with the  plaintiffs in
         the Bash lawsuit.  On March 17, 1998, the defendants  filed a motion to
         consolidate this lawsuit with the Freedman lawsuit discussed below, and
         the court granted the motion on April 24, 1998.

              Freedman,  et al. v. Value Health,  Inc., et al., No. 3:95 CV 2038
         (JCH)(D.Conn).  On September 22 and 25, 1995, two related lawsuits were
         filed against  Value Health and certain other  defendants in the United
         States District Court for the District of Connecticut.  On February 16,
         1996, a single,  consolidated class action complaint was filed covering
         both  suits  (the  Freedman  Complaint"),  naming as  defendants  Value
         Health,  Robert E. Patricelli,  William J. McBride,  Steven J. Shulman,
         David M.  Wurzer,  David J.  McDonnell,  Walter J.  McNerny,  Rodman W.
         Moorhead, III, Constance P. Newman, and John L. Vogelstein,  all former
         Value Health directors and officers, and Nunzio P. DeSantis, the former
         president  of  Diagnostek.  The Freedman  Complaint  alleges that Value
         Health and certain other defendants made false or misleading statements
         to  the  public  in  connection  with  Value  Health's  acquisition  of
         Diagnostek in 1995.  The Freedman  Complaint  asserts  claims under the
         Securities  Act of 1933 and the  Securities  Exchange Act of 1934,  and
         seeks  certification of a class consisting of all persons (with certain
         exceptions)  who  purchased  shares of Value Health common stock during
         the period March 27, 1995 (the date certain adverse  developments  were
         disclosed by Value Health). The Freedman Complaint does not specify the
         amount of damages  sought.  On March 17, 1998, the  defendants  filed a
         motion to  consolidate  this lawsuit with the Bash  lawsuit,  discussed
         above, and the motion was granted on April 24, 1998.

              In the consolidated Bash and Freedman action,  the court certified
         a class  consisting  of (i) all  persons  who  purchased  or  otherwise
         acquired  shares of VHI during the period  from April 3, 1995,  through
         and including November 7, 1995,  including those who acquired shares in
         connection  with  the  Diagnostek  merger;  and (ii)  all  persons  who
         purchased or otherwise  acquired shares of Diagnostek during the period
         from  March  27,  1995,  through  and  including  July 28,  1995.  Fact
         discovery  in the  consolidated  lawsuit is  complete.  The parties are
         awaiting an order from the court  regarding  the  scheduling  of expert
         discovery and dispositive motions.

                  In  connection  with the  Acquisition,  Columbia has agreed to
         defend and hold the Company and its affiliates (including VHI) harmless
         from and against any liability that may arise in connection with either
         of the  foregoing  proceedings.  Consequently,  the  Company  does  not
         believe it will incur any  material  liability in  connection  with the
         foregoing matters.

              In the Matter of Trading in the  Securities of Value Health,  Inc.
         On or about  September 27, 1995,  the SEC began an  investigation  into
         trading  in the  securities  of VHI  occurring  around  the time of the
         acquisition  of  Diagnostek.  The SEC  has  requested  information  and
         documentation from VHI periodically (most recently in August 1997), but
         has given no indication as to its  disposition of this matter.  As with
         the Bash and Freedman matters above,  Columbia has agreed to defend and
         hold the Company and its affiliates  (including  VHI) harmless from and
         against any liability  that may arise in  connection  with this matter.
         Consequently,  the Company  does not believe it will incur any material
         liability in connection herewith.


     In addition,  in the  ordinary  course of our  business,  there have arisen
various legal  proceedings,  investigations or claims now pending against us and
our subsidiaries  unrelated to the  Acquisition.  The effect of these actions on
future  financial  results  is not  subject  to  reasonable  estimation  because
considerable uncertainty exists about the outcomes. Nevertheless, in the opinion
of  management,  the  ultimate  liabilities  resulting  from any such  lawsuits,
investigations or claims now pending will not materially affect our consolidated
financial position, results of operations or cash flows.

     Since 1993, retail pharmacies have filed over 100 separate lawsuits against
drug  manufacturers,  wholesalers and certain PBMs,  challenging brand name drug
pricing practices under various state and federal antitrust laws. The plaintiffs
alleged,  among other things,  that the manufacturers  had offered,  and certain
PBMs had  knowingly  accepted,  discounts and rebates on purchases of brand name
prescription  drugs  that  violated  the  federal   Robinson-Patman   Act.  Some
plaintiffs also filed claims against the drug manufacturers and drug wholesalers
alleging price fixing of  pharmaceutical  drugs in violation of Section 1 of the
Sherman Act, and these claims were certified as a class action. Some of the drug
manufacturers  settled  both the  Sherman  Act and the  Robinson  Patman  claims
against them. The class action Sherman Act  settlements  generally  provide that
the  manufacturers  will not  refuse  to pay  discounts  or  rebates  to  retail
pharmacies based on their status as such.  Settlements with plaintiffs who opted
out of the class are not part of the public record.  The drug  manufacturer  and
wholesaler  defendants  in the class  action  who did not settle  were  recently
dismissed by the court on a motion for directed  verdict.  Plaintiffs  who opted
out of the class action will still have the opportunity to try their Sherman Act
claims  in   separate   lawsuits.   The  class   action  did  not   involve  the
Robinson-Patman claims, so many of those matters are still pending. We are not a
party to any of these  proceedings.  To date, we do not believe any  settlements
have had a material adverse effect on our business.  However,  we cannot provide
any assurance that the terms of the  settlements  will not materially  adversely
affect us in the future. In addition,  we cannot predict the outcome or possible
ramifications  to our business of the cases in which the  plaintiffs  are trying
their claims separately, and we cannot provide any assurance that we will not be
made a party to any such separate lawsuits in the future.


Item 4 - Submission of Matters to a Vote of Security Holders

     No matters were  submitted to a vote of security  holders during the fourth
quarter of 1998.

                                     PART II


Item 5 - Market For Registrant's Common Equity and Related Stockholder Matters

     Market Price of and Dividends on the Registrant's Common Equity and Related
Stockholder Matters

     Market Information.  Our Class A Common Stock has been traded on the Nasdaq
National  Market  ("Nasdaq")  tier of The Nasdaq  Stock  Market under the symbol
"ESRX" since June 9, 1992.  Prior to that time,  there was no public  market for
our Class A Common  Stock.  The high and low prices,  as reported by the Nasdaq,
are set  forth  below  for the  periods  indicated.  These  prices  reflect  the
two-for-one  split on October 30, 1998, in the form of a 100% stock  dividend to
holders of record on October 20, 1998.

<TABLE>
<CAPTION>

                                  Fiscal Year 1998            Fiscal Year 1997
Class A Common Stock             High          Low           High           Low
<S>                           <C>          <C>           <C>            <C>
     First Quarter            $ 42.750     $ 27.000      $ 19.125       $ 15.625
     Second Quarter             45.000       35.500        24.500         16.375
     Third Quarter              45.250       31.625        27.250         20.750
     Fourth Quarter             69.000       33.875        32.375         25.313
</TABLE>

     Our Class B Common Stock has no  established  public  trading  market,  but
those shares will  automatically  convert to Class A Common Stock on a share for
share  basis  upon  transfer  thereof  to any  entity  other  than New York Life
Insurance Company or one of its affiliates.

     Holders.  As of March 1, 1999, there were 209 stockholders of record of our
Class A Common  Stock,  and 1 holder of record of our Class B Common  Stock.  We
estimate there are  approximately  9,000 beneficial owners of the Class A Common
Stock.

     Dividends.  The Board of Directors  has not declared any cash  dividends on
our common stock since the initial public offering.  The Board of Directors does
not currently  intend to declare any cash dividends in the  foreseeable  future.
The terms of our existing credit facility contains,  and the terms of the credit
facility we intend to consummate in connection  with the pending DPS acquisition
will  contain,  certain  restrictions  on our  ability  to  declare  or pay cash
dividends.

     Recent Sales of Unregistered Securities

         None.


<PAGE>


Item 6 - Selected Financial Data


<TABLE>
                                                                       YEAR ENDED DECEMBER 31,
<CAPTION>


(IN THOUSANDS, EXCEPT PER SHARE DATA)          1998(2)           1997            1996            1995           1994
<S>                                         <C>             <C>             <C>             <C>            <C>

- -----------------------------------------------------------------------------------------------------------------------
STATEMENT OF OPERATIONS DATA:
Net revenues                                $  2,824,872    $  1,230,634    $    773,615    $    544,460   $    384,504
                                          -----------------------------------------------------------------------------
Costs and expenses:
    Cost of revenues                           2,584,997       1,119,167         684,882         478,283        338,151
    Selling, general and administrative          148,990          62,617          49,103          37,300         25,882
    Corporate restructuring                        1,651               -               -               -              -
                                          -----------------------------------------------------------------------------
                                               2,735,638       1,181,784         733,985         515,583        364,033
                                          -----------------------------------------------------------------------------
Operating income                                  89,234          48,850          39,630          28,877         20,471
Interest income (expense), net                  (12,994)           5,856           3,450             757            305
                                          -----------------------------------------------------------------------------
Income before income taxes                        76,240          54,706          43,080          29,634         20,776
Provision for income taxes                        33,566          21,277          16,932          11,307          8,053
                                          -----------------------------------------------------------------------------
Net income                                $       42,674  $       33,429   $      26,148   $      18,327  $      12,723
                                          =============================================================================
Earnings per share(3)
     Basic                                $         1.29  $         1.02   $        0.81   $        0.62  $        0.43
     Diluted                              $         1.27  $         1.01   $        0.80   $        0.60  $        0.42



Weighted average shares outstanding(3)
     Basic                                        33,105          32,713          32,160          29,560         29,588
     Diluted                                      33,698          33,122          32,700          30,545         30,293
- -----------------------------------------------------------------------------------------------------------------------
Balance Sheet Data:
Cash                                       $     122,589  $       64,155   $      25,211   $      11,506   $      5,742
Working capital                                  117,611         166,062         128,259          58,653         38,082
Total assets                                   1,095,461         402,508         300,425         164,088        108,922
Debt:
     Short-term debt                              54,000
     Long-term debt                              306,000
Stockholders' equity                             249,694         203,701         164,090          77,379         52,485
- -----------------------------------------------------------------------------------------------------------------------
Selected Data:
Pharmacy benefit covered lives                    23,000          13,000          10,000           8,000          6,000
Annual drug spending(3)                     $  4,495,000    $  2,486,000    $  1,636,000    $  1,172,000     $  716,000
Pharmacy network  claims processed               113,177          73,164          57,838          42,871         26,323
Mail pharmacy  prescriptions filled                7,426           3,899           2,770           2,129          1,594
EBITDA(4)                                   $    115,667    $     59,320    $     46,337    $     33,258     $   23,795


Cash flows provided by operating
activities                                  $    126,574    $     52,503    $     29,863    $     11,500     $    9,741

Cash flows used in investing
activities                                  $   (426,052)   $    (16,567)   $    (64,808)   $     (8,047)    $   (6,348)

Cash flows provided by financing
activities                                  $    357,959    $      3,033    $     48,652    $      2,311     $      314
- -----------------------------------------------------------------------------------------------------------------------
<FN>
     (1)Earnings  per share and weighted  average shares  outstanding  have been
restated to reflect the two-for-one stock split effective October 30, 1998.

     (2)Includes  the  acquisition  of ValueRx  effective  April 1,  1998.  Also
includes a corporate  restructuring charge in 1998 of $1,651 ($1,002 after tax).
Excluding this  restructuring  charge,  our basic and diluted earnings per share
would  have  been  $1.32  and  $1.30,  respectively.

     (3)Annual drug spending is a measure of the gross aggregate dollar value of
drug expenditures of all programs managed by the Company. The difference between
annual drug spending and revenue reported by the Company is the combined effect
of excluding from reported revenues: (i)the drug ingredient cost for those
clients that have established their own pharmacy networks; (ii) the expenditures
for drugs for companies on formulary-only programs managed by the Company; and
(iii) the co-pay portion of drug expenditures that are the responsibility of
members of health plans serviced by the Company.  Therefore, annual drug
spending provides a common basis to compare the drug expenditures managed by a
company given differences in revenue recognition.

     (4)EBITDA   is  earnings   before   interest,   taxes,   depreciation   and
amortization, (operating income plus depreciation and amortization). EBITDA is
presented because it is a  widely  accepted  indicator  of a  company's  ability
to incur  and  service indebtedness. EBITDA, however, should not be considered
as an alternative to net income, as a measure of operating performance, as an
alternative to cash flow or as a measure of  liquidity.  In addition,  our
EBITDA definition may not be comparable to similar measures reported by other
companies.

</FN>
</TABLE>



<PAGE>

Item 7 - Management's Discussion and Analysis of Financial Condition and Results
of Operations


OVERVIEW


     During  1998,  the  Company  continued  executing  its growth  strategy  of
generating  sales to new clients,  expanding  the services  provided to existing
clients,  developing new products and services for sale to existing  clients and
pharmaceutical manufacturers and selectively pursuing strategic acquisitions and
alliances. On April 1, 1998, the Company consummated its first major acquisition
by  acquiring   "ValueRx",   the  PBM  operations  of  Columbia/HCA   Healthcare
Corporation,  for approximately $460 million in cash, which included transaction
costs and  executive  severance  costs of  approximately  $6.7  million and $8.3
million,  respectively.  Specifically, the Company acquired various subsidiaries
of Columbia each now or formerly conducting business as a PBM, including ValueRx
Pharmacy  Program,  Inc. The  acquisition  was  accounted for under the purchase
method of accounting.  Consequently,  the Company's  operating  results  include
those  of  ValueRx  from  April 1,  1998.  The net  assets  acquired  have  been
preliminarily  recorded at their estimated fair value, resulting in $289,863,000
of goodwill which is being amortized over 30 years.

     The  acquisition of ValueRx  enabled the Company to increase  membership to
approximately  23 million  lives as of December 31, 1998 from  approximately  13
million lives as of December 31, 1997,  representing an 81.7% increase. In 1997,
the  Company  increased  membership  by  approximately  3 million  lives from 10
million  lives as of December  31,  1996,  representing  a 27.3%  increase.  The
increase in membership in 1997 was primarily due to internal growth.  Reflecting
the addition of new clients  implemented  at January 1, 1999,  the Company's net
membership increased  approximately 1 million to approximately 24 million lives.
Although  membership  counts are based on  eligibility  data,  they  necessarily
involve some estimates,  extrapolations and  approximations.  For example,  some
plan designs allow for family coverage under one identification  number, and the
Company  makes  assumptions  about the  average  number of persons per family in
calculating  its total  membership.  Because these  assumptions may vary between
PBMs,  membership  counts may not be comparable  between us and our competitors.
However,  the  Company  believes  its  membership  count  provides a  reasonable
estimation of the  population  it serves,  and can be used as one measure of its
growth.

     The Company primarily derives its revenues from the sale of PBM services in
the United States and Canada.  The Company's PBM net revenues  generally include
administrative  fees,  dispensing fees and ingredient  costs of  pharmaceuticals
dispensed from retail  pharmacies  included in one of the Company's  networks or
from one of the Company's mail  pharmacies  and records the associated  costs in
cost of revenues.  Net revenues  from these  activities  in 1998,  1997 and 1996
represented 98.3%, 97.7%, and 97.3%, respectively,  of total net revenues. Where
the Company only administers the contracts  between its clients and the clients'
retail  pharmacy  networks,  the  Company  records  as  net  revenues  only  the
administrative fee it receives from its activities. The Company also derives PBM
net revenues from the sale of informed decision  counseling services through its
Express Health LineSM division,  and the sale of medical information  management
services, which include provider profiling,  disease management support services
and outcomes assessments through its PPS subsidiary. In 1998, 1997 and 1996, net
revenue  from  these  services,  including  where  administrative  fees only are
recognized,  represented  1.7%,  2.3% and 2.7%,  respectively,  of net  revenues
reported in our consolidated  statement of operations.  Non-PBM net revenues are
derived from (i) the sale of  pharmaceuticals  for and the provision of infusion
therapy services through its IVTx subsidiary,  (ii) administrative fees received
for members using the Company's  vision  program  through its alliance with Cole
Managed Vision ("Cole"),  a subsidiary of Cole National  Corporation,  and (iii)
administrative  fees  received  from drug  manufacturers  for the  dispensing of
pharmaceuticals through its Specialty Distribution division.


RESULTS OF OPERATIONS

<TABLE>
<CAPTION>

NET REVENUES

                                   Year Ended December 31,
(in thousands)     1998        Increase       1997        Increase        1996
<S>               <C>             <C>        <C>               <C>       <C>
- --------------------------------------------------------------------------------

  PBM             $ 2,765,111     132.1%     $ 1,191,173       60.3%     743,077
  Non-PBM              59,761      51.4%          39,461       29.2%      30,538
                  ==============================================================
Net revenues      $ 2,824,872     129.5%     $ 1,230,634       59.1%     773,615
                  ==============================================================
</TABLE>


         The Company  experienced  significant growth in its net revenues during
1998 over 1997  primarily  due to the  acquisition  of ValueRx  and, to a lesser
extent,  the  Company's  continuing  ability to attract  new  clients as well as
additional members from existing clients.  Net revenues for the network pharmacy
claims  services  increased  $1,175,659,000,  or  141.7%,  in 1998 over 1997 and
increased  $311,195,000,  or 60.0%,  in 1997 over 1996.  These increases are the
result of growth in the number of network  pharmacy claims processed of 54.7% in
1998 over 1997 and of 26.5% in 1997 over 1996,  and an  increase  in the average
net  revenue  per  network  pharmacy  claim of 56.3%  in 1998  over  1997 and an
increase  of 26.6% in 1997 over 1996.  The  increase  in average net revenue per
network  pharmacy  claim for both  periods  is  primarily  due to the  following
factors:  (i)  a  larger  number  of  clients  using  retail  pharmacy  networks
established by the Company rather than retail pharmacy  networks  established by
our  clients,  which  results  in the  Company  recording  dispensing  fees  and
ingredient  costs in net revenues and cost of revenues,  respectively,  and (ii)
higher drug ingredient  costs resulting from price increases for existing drugs,
new drugs  introduced  into the  marketplace  and changes in therapeutic mix and
dosage.  These  increases were partially  offset by lower pricing offered by the
Company in response to continued competitive pressures.


     The number of clients using retail  pharmacy  networks  established  by the
Company increased  significantly  beginning in the second quarter of 1998 due to
the acquisition of ValueRx, as substantially all ValueRx clients used the retail
pharmacy  networks  established  by ValueRx.  As a result of this  shift,  gross
margin  percentages are reduced but the dollar amount of the gross profit is not
significantly affected.

     Net revenues for mail pharmacy services increased $385,149,000,  or 109.6%,
in 1998 over 1997 and $129,273,000, or 58.2%, in 1997 over 1996. These increases
are the result of the growth in mail pharmacy claims  processed of 90.5% in 1998
over  1997 and 40.8% in 1997 over  1996,  and an  increase  in the  average  net
revenue  per mail  pharmacy  claim of 10.0% in 1998  over 1997 and 12.4% in 1997
over 1996.  The increase in the average net revenue per mail pharmacy  claim for
both periods is primarily due to the following  factors:  (i) the termination of
inventory replacement programs maintained for two large clients during 1997; and
(ii) higher drug  ingredient  costs.  These  increases were partially  offset by
lower  pricing  offered by the  Company in  response  to  continued  competitive
pressures.

     Under the inventory replacement programs offered in 1996 and the first four
months of 1997,  the client  provided drug inventory on consignment to fill mail
service prescriptions for members of the client's plan, and the Company included
only its  dispensing  fee as net  revenue.  For 1998 and most of 1997,  all mail
pharmacy  clients  utilized the Company's  standard program in which the Company
purchases and takes title to the inventory used to fill the  prescriptions  and,
therefore,  includes the ingredient  costs as well as the dispensing fees in net
revenues. This change had the effect of increasing both net revenues and cost of
revenues during 1998 and 1997 compared to 1997 and 1996, respectively, but there
was no significant effect on the Company's reported gross margin during 1998 and
1997 from the  conversion to the standard  program.  In addition,  the Company's
inventory  levels increased  substantially  during 1997 over 1996 as a result of
the termination of the inventory replacement program.

     Net revenues for the Company's  non-PBM  services  increased  51.4% in 1998
over 1997 and 29.2% in 1997 over 1996. The increases are primarily  attributable
to the  continued  growth in the number of members  and/or  clients  who receive
these  services,  higher  drug  ingredient  costs and the  Company's  ability to
develop new products and services.

COST AND EXPENSES


COST AND EXPENSES
<TABLE>
                                              YEAR ENDED DECEMBER 31,
<CAPTION>

(IN THOUSANDS)                        1998        INCREASE       1997        INCREASE       1996
<S>                                 <C>             <C>       <C>              <C>       <C>
- -------------------------------------------------------------------------------------------------
PBM                                 $ 2,540,360     133.4%    $1,088,225       64.4%     $661,946
 Percentage of pbm net revenues           91.9%                    91.4%                    89.1%
Non-PBM                                  44,637      44.3%        30,942       34.9%     $ 22,936
 Percentage of non-pbm net                74.7%                    78.4%                    75.1%
 revenues
                                    -------------------------------------------------------------
Cost of revenues                      2,584,997     131.0%     1,119,167      63.4%     $684,882
 Percentage of net revenues               91.5%                    90.9%                   88.5%

Selling, general and administrative     130,116     127.2%         57,257     23.8%       46,267
 Percentage of net revenues                4.6%                      4.7%                   6.0%

Depreciation and amortization (1)        18,874     252.1%          5,360     89.0%        2,836
 Percentage of net revenues                0.7%                      0.4%                   0.4%

Corporate restructuring expense           1,651       NM               -        NM            -
 Percentage of net revenue                 0.0%                      0.0%                   0.0%
                                    =============================================================
Total cost and expenses             $ 2,735,638     131.5%    $ 1,181,784     61.0%     $733,985
                                    =============================================================
 Percentage of net revenues               96.8%                     96.0%                   94.9%

<FN>
     (1) Represents  depreciation and amortization  expense included in selling,
general and  administrative  expenses on the Company's  Statement of Operations.
Cost of revenues,  above,  includes  depreciation  and  amortization  expense on
property, plant and equipment. nm = not meaningful

</FN>
</TABLE>


     The Company's  cost of revenues for PBM services as a percentage of PBM net
revenues   continued   to  increase  in  1998  and  1997  over  1997  and  1996,
respectively.  Cost of revenues for the Company's  pharmacy  network  claims and
mail pharmacy claims increased 145.5% and 106.7% during 1998 and 65.7% and 60.2%
during  1997,  respectively.  The PBM gross  margin as a  percentage  of PBM net
revenues declined 0.5 percentage points during 1998 over 1997 and 2.3 percentage
points during 1997 over 1996. The decrease in gross margin percentage in 1997 is
due to the shift toward pharmacy networks established by the Company, as opposed
to those  established  by its  clients,  higher  drug  ingredient  costs and the
termination of the inventory  replacement programs, as discussed above in "--Net
Revenues."  The decrease in gross margin  percentage in 1998 is primarily due to
the shift towards  pharmacy  networks  established by the Company.  The pharmacy
network  shift  continued  due to the  acquisition  of  ValueRx,  as the ValueRx
clients  primarily used retail pharmacy  networks  established by ValueRx.  This
decrease  was  partially  offset  by  operating  efficiencies  achieved  in  the
Company's mail pharmacies during 1998 and revenues generated from integrated PBM
services,  such as medical and drug data  analysis,  that  provide  higher gross
margins.

     Cost of revenues for non-PBM services  decreased as a percentage of non-PBM
net revenues from 1997 primarily due to the Company developing new business that
generates  higher gross margins of $11,039,000.  These higher gross margins were
partially  offset by increasing  costs of $2,320,000  associated  with continued
expansion of certain operations and continued change of approximately $3,040,000
in the product mix sold in 1998  compared to 1997.  Cost of revenues for non-PBM
services  increased  as a  percentage  of non-PBM net revenues in 1997 over 1996
primarily due to increasing costs associated with continued expansion of certain
operations.

     Selling,  general and  administrative  expenses increased  $72,859,000,  or
127.2%,  in 1998 over 1997 and  $10,990,000,  or 23.8%,  in 1997 over 1996.  The
increase  during 1998 was the result of the  Company's  acquisition  of ValueRx,
costs  incurred  during the  integration of ValueRx and costs required to expand
the operational and  administrative  support functions to enhance  management of
the  pharmacy  benefit.  The  increase  during  1997  was  primarily  due to the
expansion of the operational  and  administrative  support  functions to enhance
management of the pharmacy  benefit.  As a percentage of net revenues,  selling,
general and  administrative  expenses for 1998  decreased  slightly to 4.6% from
4.7% in 1997.  In 1997,  selling,  general  and  administrative  expenses,  as a
percentage of net revenues,  decreased 1.3 percentage  points from 6.0% in 1996.
Selling,  general and administrative  expenses, as a percentage of net revenues,
in both periods were affected by the Company  recording  higher net revenues due
to the shift towards pharmacy networks established by the Company, as opposed to
those   established  by  its  clients  and  the  termination  of  the  inventory
replacement programs, as discussed above for "Net Revenues."

     As part of its overall plan to achieve operating economies, the Company has
been integrating ValueRx into its historical business.  During 1998, the Company
substantially  met its  integration  goals by combining  existing  contracts and
contracting  procedures  related to both  suppliers and  providers;  integrating
financial reporting systems,  reducing the ValueRx computer systems from five to
three,   consolidating   financial  operations,   consolidating   organizational
structure  and employee  benefits,  and  implementing  a new sales and marketing
program for enhanced  PBM  services.  The Company  expects to reduce the ValueRx
computer  systems to one by  October,  1999.  Except  for  certain  new  systems
development costs, the Company is expensing integration costs as incurred. As of
December  31,  1998,  the  Company  has  capitalized  $5,209,000  in new systems
development costs and has expensed $8,331,000 in incremental integration costs.


     Depreciation and amortization substantially increased during 1998 over 1997
due  to  the  acquisition  of  ValueRx.   During  1998,  the  Company   recorded
amortization  expense for goodwill and other  intangible  assets of $12,183,000.
The  remaining  increases  in 1998  and 1997 are  primarily  due to the  Company
expanding its operations and enhancing its information  systems to better manage
the pharmacy benefit.


     On June 17, 1998,  the Company  announced  that it had reached an agreement
with Cole,  pursuant to which Cole will provide certain vision care services for
the Company's  clients and their members.  The agreement  enables the Company to
focus on its PBM  business  while still  offering  vision  care  services to its
members by  transferring  certain  functions  performed  by its Express  Scripts
Vision Corporation to Cole, effective September 1, 1998. In conjunction with the
agreement,  the Company  also  announced  plans to close the  operations  of its
wholly-owned  subsidiary,  PhyNet,  Inc., a vision program  management  services
organization  that is part of our non-PBM  services  segment.  As a result,  the
Company recorded a one-time restructuring charge of $1,651,000 in 1998 comprised
of asset write-downs to their net realizable  value,  less cost of disposal,  of
$1,235,000  and expected  employee  transition  cash payments of $416,000 for 61
employees.  During  1998,  the Company  incurred  cash  payments of $184,000 for
employee  transition and non cash  adjustments of $704,000 for the write-down of
assets.  The Company  anticipates  completing the remainder of the restructuring
transactions by the end of the third quarter of 1999.


<TABLE>
<CAPTION>

INTEREST INCOME (EXPENSE), NET

                                                                Year Ended December 31,
(in thousands)                                 1998        Increase       1997        Increase        1996
<S>                                         <C>             <C>         <C>             <C>
- --------------------------------------------------------------------------------------------------------------
Interest expense                            $  (20,230)         nm      $    (225)          nm      $    (59)
    Percentage of net revenues                    -0.7%                       0.0%                       0.0%
Interest income                                   7,236      19.0%           6,081       73.3%          3,509
    Percentage of net revenues                     0.2%                       0.5%                       0.5%

                                        ======================================================================
Interest income (expense), net              $  (12,994)         nm       $   5,856       69.7%      $   3,450
                                        ======================================================================
    Percentage of net revenues                    -0.5%                       0.5%                       0.5%
</TABLE>

nm = not meaningful

     During 1998, the Company recorded  significant  interest expense  resulting
from the  financing of the ValueRx  acquisition  with $360 million in borrowings
(see "Liquidity and Capital Resources").  Interest income increased  $1,155,000,
or 19.0%,  in 1998 over 1997 and  $2,572,000,  or 73.3% in 1997 over  1996.  The
increases  in  1998  and  1997  are due to the  Company  investing  larger  cash
balances.  In addition, in 1997 the larger cash balances were invested at higher
interest rates than those in 1996.

<TABLE>
<CAPTION>

PROVISION FOR INCOME TAXES

                                                          Year Ended December 31,
(in thousands)                          1998        Increase       1997        Increase        1996
<S>                                 <C>             <C>        <C>              <C>       <C>
- -----------------------------------------------------------------------------------------------------
Provision for income taxes          $   33,566      57.8%      $   21,277       25.7%     $   16,932
Effective tax rate                       44.0%                      38.9%                      39.3%
</TABLE>

     The  Company's  effective  tax rate  increased in 1998 over 1997 due to the
non-deductible  goodwill and client contract amortization expense resulting from
the  ValueRx  acquisition.  It is  expected  that the  effective  tax rate  will
gradually  decline towards the statutory rate as the Company's  operating growth
continues.


<TABLE>
<CAPTION>

NET INCOME AND EARNINGS PER SHARE

                                                                  Year Ended December 31,
(in thousands)                                  1998        Increase       1997        Increase        1996
<S>                                          <C>             <C>        <C>              <C>       <C>
- --------------------------------------------------------------------------------------------------------------

Net income                                   $   42,674      27.7%      $   33,429       27.8%     $   26,148
    Percentage of net revenue                      1.5%                       2.7%                       3.4%

Basic earnings per share                      $    1.29      26.5%       $    1.02       25.9%      $    0.81

Weighted average shares outstanding                           1.2%                        1.7%         32,160
                                                 33,105                     32,713

Diluted earnings per share                    $    1.27      25.7%       $    1.01       26.3%      $    0.80

Weighted average share outstanding                            1.7%                        1.3%
                                                 33,698                     33,122                     32,700
</TABLE>

     The Company's net income  increased  $9,245,000 or 27.7% in 1998 over 1997,
and  $7,281,000 or 27.8% in 1997 over 1996.  Excluding  the  after-tax  one-time
corporate  restructuring  charge for the managed vision  business of $1,002,000,
basic earnings per share and diluted earnings per share for 1998 would have been
$1.32 and $1.30, respectively.


     On October 12, 1998, the Company announced a two-for-one stock split of its
Class A and Class B common stock for stockholders of record on October 20, 1998,
effective  October 30, 1998. The split was effected in the form of a dividend by
issuance of one additional share of Class A common stock for each share of Class
A common stock  outstanding and one additional share of Class B common stock for
each share of Class B common stock  outstanding.  The earnings per share and the
weighted average number of shares outstanding for basic and diluted earnings per
share for each period have been adjusted for the stock split.


LIQUIDITY AND CAPITAL RESOURCES
<TABLE>
<CAPTION>

                                                           Year Ended December 31,
(in thousands)                         1998        Increase       1997        Increase        1996
<S>                                  <C>           <C>          <C>            <C>        <C>
- -----------------------------------------------------------------------------------------------------

Net cash provided by operations      $ 126,574     141.1%       $  52,503      75.8%      $  29,863
</TABLE>


     The  increase in  operating  cash flow  generated in 1998 by the Company is
primarily due to the increase in net income and its continued focus on improving
working  capital  management.  The increase in operating  cash flow generated in
1997 is primarily  due to the  increase in net income and the Company  beginning
its working capital  management focus. The operating cash flow generated in 1996
is primarily due to the increase in net income.  Management  expects to fund its
future debt  service,  integration  costs,  Year 2000 costs,  internet  business
development costs and other normal operating cash needs primarily with operating
cash flow or, to the extent necessary, with working capital borrowings under the
$1.05 billion credit  facility the Company  intends to obtain in connection with
the DPS acquisition (see below).

     The Company's capital  expenditures in 1998 increased  $10,836,000 or 83.2%
over  1997  primarily  due to the  Company's  concerted  effort to invest in its
information  technology  to enhance the  services  provided to its  clients.  In
addition,  the Company  invested in equipment to improve  efficiency at its mail
pharmacy facilities and to manage the growth encountered at these facilities. In
1997, capital  expenditures  increased  $3,537,000 or 37.3% primarily due to the
investments required for the Company to manage its growth. Management expects to
continue  investing  in  technology  that  will  provide   efficiencies  in  its
operations,  manage its growth and enhance the service  provided to its clients.
Management expects to fund its future anticipated capital expenditures primarily
with  operating  cash flow or, to the extent  necessary,  with  working  capital
borrowings under the $1.05 billion credit facility the Company intends to obtain
in connection with the DPS acquisition (see below).


     During the first  quarter of 1998,  the Company  negotiated  a $440 million
credit  facility  with a  bank  syndicate  led by  Bankers  Trust  Company.  The
five-year  agreement became effective April 1, 1998, and included a $360 million
term loan facility and an $80 million  revolving  loan  facility.  The term loan
proceeds were utilized to consummate the  acquisition of ValueRx.  The agreement
is  guaranteed  by the  Company's  domestic  subsidiaries  other  than  Practice
Patterns  Science,  Inc.  ("PPS") and Great Plains  Reinsurance  Company ("Great
Plains")   and  secured  by  pledges  of  100%  (or,  in  the  case  of  foreign
subsidiaries, 65%) of the capital stock of the Company's subsidiaries other than
PPS and Great Plains.  The provisions of this credit facility require  quarterly
interest payments and, beginning in April 1999,  semi-annual  principal payments
of $27 million, increasing to $36 million in April 2000, to $45 million in April
2001 and to $48 million in April 2002.  The  interest  rate is based on a spread
(the "Credit Rate Spread") over several London Interbank Offered Rates ("LIBOR")
or base rate  options,  depending  upon the Company's  ratio of earnings  before
interest,  taxes,  depreciation  and amortization to debt. At December 31, 1998,
the interest rate was 6.0625%,  representing  a Credit Rate Spread of 0.75% over
the three-month LIBOR rate. This credit facility contains  covenants that limit:
(i) the indebtedness the Company may incur, and (ii) the amount of the Company's
annual  capital  expenditures.  The  covenants  also  establish:  (i) a  minimum
interest  coverage ratio,  (ii) a maximum  leverage  ratio,  and (iii) a minimum
consolidated net worth. At December 31, 1998, the Company was in compliance with
all  covenants.  In  addition,  the  Company is  required  to pay an annual fee,
depending  on the leverage  ratio,  payable in  quarterly  installments,  on the
unused portion of the revolving  loan. The commitment fee was 0.225% at December
31,  1998.  As a result of this credit  facility,  the Company  canceled its $25
million line of credit with Mercantile Bank of St. Louis on March 31, 1998.


     In connection  with its acquisition of DPS, the Company intends to obtain a
$1.05 billion  credit  facility from a bank syndicate led by Credit Suisse First
Boston and Bankers Trust Company and a $150 million senior  subordinated  bridge
credit  facility from Credit Suisse First Boston and Bankers Trust Company.  The
proceeds  of the  facilities  will be  used  to  purchase  DPS  and  retire  the
outstanding $360 million  principal balance on the company's $440 million credit
facility with Bankers Trust Company. The $1.05 billion credit facility will also
provide a revolving line of credit to meet working  capital needs.  In addition,
the Company  expects to issue $350  million in Class A Common  Stock  through an
offering.  The proceeds from the offering will be used to repay the $150 million
subordinated  bridge credit facility and a portion of the intended $1.05 billion
credit facility.

     To alleviate  interest rate  volatility in connection with its $440 million
credit facility,  the Company entered into an interest rate swap arrangement for
a notional  principal amount of $360 million effective April 3, 1998, with First
National Bank of Chicago, a subsidiary of Bank One Corporation.  Under the terms
of the swap,  the Company  agreed to receive a floating  rate of interest on the
amount of the term loan portion of the  facility  based on a  three-month  LIBOR
rate in exchange for payment of a fixed rate of interest of 5.88% per annum. The
notional  amount of the swap is  amortized in equal  amounts with the  principal
balance of the term loan. As a result, the Company had, in effect, converted its
variable  rate  term debt to fixed  rate debt at 5.88% per annum for the  entire
term of the term loan,  plus the Credit Rate  Spread.  The  Company  anticipates
maintaining  its  interest  rate  swap in  place to hedge  the  future  variable
interest  rate  payments on $360 million of the intended  $1.05  billion  credit
facility.

     As of December 31,  1998,  the Company had  repurchased  a total of 475,000
shares  of its  Class A common  stock  under the  open-market  stock  repurchase
program  announced by the Company on October 25, 1996,  although no  repurchases
occurred during 1998. The Company's  board of directors  approved the repurchase
of up to  1,700,000  shares and placed no limit on the  duration of the program.
Future  purchases,  if any,  will be in such  amounts  and at such  times as the
Company deems appropriate based upon prevailing market and business  conditions,
subject to certain  restrictions on stock repurchases in the Company's  intended
$1.05 billion credit facility.

     The Company  has  reviewed  and  intends to  continue  to review  potential
acquisitions and affiliation opportunities.  The Company believes that available
cash resources,  bank financing or the issuance of additional common stock could
be used to finance such acquisitions or affiliations.  However,  there can be no
assurance the Company will make other  acquisitions  or  affiliations in 1999 or
thereafter.


OTHER MATTERS


     On March 16, 1998,  the Company  announced  that,  in  connection  with the
consummation of the sale by New York Life Insurance Company ("New York Life") of
NYLCare Health Plans, Inc.  ("NYLCare") to Aetna U.S.  Healthcare Inc. ("Aetna")
(which  occurred  on July 15,  1998),  the  Company  and  Aetna had  reached  an
agreement to extend the  Company's  PBM services and infusion  therapy  services
agreements to HMO members  through  December 31, 2003. The existing PBM contract
pricing  is  effective  through  December  31,  1999,  and  thereafter   pricing
adjustments, based upon prevailing market conditions, will be instituted for the
year 2000 and subsequent  periods.  The agreement  between Aetna and the Company
provides  that the Company  will  continue  providing  PBM  services,  excluding
informed  decision  counseling  services,  to over 1 million HMO members through
2003,  which is  comparable  to the  NYLCare HMO  membership  base served by the
Company prior to the Aetna  acquisition.  The infusion  therapy  agreements  are
extended  under their  current  terms until  December 31, 2000,  and  thereafter
limited price  adjustments  may take effect under  specific  circumstances.  The
terms of this  arrangement  were  negotiated  with  Aetna at arm's  length.  The
Company believes all fee components  reflect an appropriate market price for our
services,  and any pricing  adjustments will be immaterial to us, based upon the
form of the pricing  adjustment and the relative  contribution of this client to
our overall operating results.  The existing  agreements for managed vision care
and informed  decision  counseling  will continue  until  December 31, 1999. The
Company  expects to continue  providing  PBM  services to members of the NYLCare
indemnity  programs  until such members are  converted  to new health  insurance
policies,  which is  anticipated to occur  primarily  during 1999. In connection
with the Aetna  arrangement,  the  Company  and New York Life  have  reached  an
agreement  in  principle  whereby  New York Life may make up to $2.8  million of
certain  transition-related  payments to the Company in 1999, depending upon the
level of profit the Company  would  derive from the  provision  of selected  PBM
services  to Aetna,  compared  to an estimate of the profit that would have been
derived had the NYLCare/Aetna  transaction not taken place, using certain agreed
upon assumptions  about profit margins,  membership  levels and drug utilization
rates.  The overall  impact of this  arrangement  on  earnings  per share is not
expected to be material in 1999.


     During 1998 and 1997,  4.8% and 15.7%,  respectively,  of the Company's PBM
net revenues were from services  provided to members of HMOs owned or managed by
NYLCare or  insurance  policies  administered  by NYLCare  while it was a wholly
owned  subsidiary  of New York Life.  Of the  Company's net revenues for non-PBM
services,  21.5%  and 54.8% in 1998 and 1997,  respectively,  were for  services
provided  to members of HMOs owned or managed by NYLCare or  insurance  policies
administered by NYLCare while it was a wholly owned subsidiary of New York Life.

     Effective with the first quarter of 1998, the Company adopted  Statement of
Financial  Accounting  Standards Statement 130, Reporting  Comprehensive  Income
("FAS 130").  FAS 130 requires  noncash  changes in  stockholders'  equity to be
combined  with net income and  reported in a new  financial  statement  category
entitled  comprehensive  income.  Other than net income,  the only  component of
comprehensive  income  for the  Company is the  change in the  foreign  currency
translation account.

     Effective  with fiscal  year end 1998,  the Company  adopted  Statement  of
Financial  Accounting  Standards Statement 131, Disclosures About Segments of an
Enterprise  and Related  Information  ("FAS  131").  FAS 131  requires  that the
Company  report  certain  information  if  specific  requirements  are met about
operating  segments  of  the  Company,  including  information  about  services,
geographic  areas of operation and major  customers.  The  information  is to be
derived from the management approach, which designates the internal organization
that is  used  by  management  for  making  operating  decisions  and  assessing
performance as the source of the Company's operating  segments.  Adoption of FAS
131 did not affect the Company's results of operations or its financial position
but did affect the  disclosure of segment  information  (see Note 13 in our 1998
Consolidated Financial Statements).

     In June 1998,  Statement of Financial  Accounting  Standards Statement 133,
Accounting for Derivative  Instruments  and Hedging  Activities  ("FAS 133") was
issued.  FAS 133 requires all  derivatives  to be recognized as either assets or
liabilities  in the statement of financial  position and measured at fair value.
In addition, FAS 133 specifies the accounting for changes in the fair value of a
derivative  based  on the  intended  use of the  derivative  and  the  resulting
designation.  FAS 133 is  effective  for all  fiscal  quarters  of fiscal  years
beginning  after June 15, 1999,  and will be applicable  to the Company's  first
quarter of fiscal  year 2000.  The  Company's  present  interest  rate swap (see
"--Liquidity  and Capital  Resources")  would be  considered  a cash flow hedge.
Accordingly,  the change in the fair value of the swap would be  reported on the
balance sheet as an asset or liability.  The  corresponding  unrealized  gain or
loss  representing  the  effective  portion  of  the  hedge  will  be  initially
recognized  in  stockholders'   equity  and  other   comprehensive   income  and
subsequently any changes in unrealized gain or loss from the initial measurement
date will be recognized in earnings  concurrent with the interest expense on the
Company's  underlying  variable rate debt. If the Company had adopted FAS 133 as
of December 31, 1998,  the Company  would have recorded the  unrealized  loss of
$7,209,000  as a  liability  and  reduction  in  stockholders'  equity and other
comprehensive income.

POST YEAR-END EVENTS


     On March 29, 1999,  the Company  announced its plans to launch two internet
sites,  YourPharmacy.com and DrugDigest.org.  YourPharmacy.com  will serve as an
online drug store and offer both prescription and over-the-counter  medications,
vitamins,  herbs  and  health  and  beauty  aids.  DrugDigest.org  will  provide
fact-based  information on a variety of  medications,  vitamins and herbs.  Both
sites are  expected  to be  operational  during the second  quarter of 1999.  By
allowing the Company to communicate  more  effectively and efficiently  with its
existing  members,  the Company should be able to reduce its operating  costs by
utilizing  on-line  communication  as  opposed  to more  expensive  call  center
operations and paper-based  correspondence.  To date, the Company has funded the
development of the internet sites through  operating cash flows and has expensed
these  amounts  as  incurred.  The  Company  expects  to  continue  funding  the
development  and  operation  of these  sites with  operating  cash flows or with
working capital borrowings under its intended $1.05 billion credit facility.

     On February 9, 1999,  the Company  announced  its  definitive  agreement to
acquire  DPS for $700  million in cash.  The  Company  intends  to  finance  the
acquisition  through a $1.05 billion  credit  facility and a $150 million senior
subordinated  bridge credit facility (see "--Liquidity and Capital  Resources").
The  acquisition  will be accounted for under the purchase  method of accounting
and is subject to customary  closing  conditions and consummation and funding of
the  committed  bank  credit  facility  and senior  subordinated  bridge  credit
facility.  The  Company  anticipates  the  transaction  will close in the second
quarter  of 1999 and  expects  to issue  $350  million  in Class A Common  Stock
through a public  offering.  The net  proceeds of the  offering  will be used to
repay the senior subordinated bridge credit facility and a portion of the credit
facility.

     Under the  Company's  agreement  to  acquire  DPS,  SmithKline  Beecham  is
obligated  to  dissolve  a joint  venture  relationship  in a  company  known as
Diversified   Prescription  Delivery  ("DPD"),   which  provides  mail  pharmacy
services,  including  services for some clients of DPS.  SmithKline  Beecham has
executed a letter of intent to acquire the 50%  interest in DPD that it does not
currently  own.  Following  the  acquisition  of this 50%  interest,  SmithKline
Beecham  will  transfer  ownership  of DPD to the  Company or to another  entity
controlled  by the  Company.  The Company  will not pay  SmithKline  Beecham any
additional amounts beyond what it has already paid to acquire DPS.  Consummation
of this  transaction is subject to conditions,  including  preparation of formal
contract documents and the approval of regulatory authorities.

     On February 1, 1999, the Company announced a three-and-a-half-year contract
with Blue Cross and Blue Shield of  Massachusetts  ("BCBSMA").  Beginning in the
second half of 1999,  the Company will provide  retail network and mail pharmacy
services,  claims  processing,  clinical  management  support and other  related
services to approximately 1 million BCBSMA members.



YEAR 2000

     The Company's  operations  rely heavily on computers and other  information
systems  technologies.  In 1995,  the Company began  addressing  the "Year 2000"
issue,  which refers to the  inability of certain  computer  systems to properly
recognize  calendar dates beyond  December 31, 1999.  This arises as a result of
systems having been programmed with two digits rather than four digits to define
the applicable  year in order to conserve  computer  storage  space,  reduce the
complexity of calculations and produce better performance.  The two-digit system
may cause  computers to interpret the year "00" as "1900" rather than as "2000",
which may cause system failures or produce  incorrect  results when dealing with
date-sensitive information beyond 1999.

     The Company  formed a Year 2000 task force to address this issue.  The task
force has  performed a  self-assessment  and  developed a  compliance  plan that
addresses,   in  light  of  applicable  industry  standards,   the  testing  and
modification of:


     -        internally developed application software
     -        vendor developed application software
     -        operating system software
     -        utility software
     -        vendor/trading partner-supplied files
     -        externally provided data or transactions
     -        non-information technology devices that are material to the
              Company's business.

The  Company's  plan covers  both the  traditional  Express  Scripts and ValueRx
systems.  Progress in each area is monitored  and  management  reports are given
periodically.


     The  Company  has  various  applications  and  operating  systems  that are
considered  critical to its operations.  Approximately 75% of these systems have
been  tested  in  an  integrated  environment  by  the  Company  for  Year  2000
compliance.  The  remaining  systems  will either be tested  and, if  necessary,
modified  to be  compliant  by  the  end of  the  second  quarter  of  1999,  or
information  residing  on such  systems  will  be  integrated  into a Year  2000
compliant  operating  system.  Testing of the applications and operating systems
includes the  adjudication  process,  the eligibility  process,  the billing and
remittance  process,  the  communication  process  and  the  reporting  process,
including  financial  reporting.  In addition,  since 1995,  all new  internally
developed  software  has been  developed to be Year 2000  compliant  and will be
fully tested during the remainder of 1999.


     The Company is  participating  in a joint  effort  with other PBMs,  retail
pharmacy chains, transaction routing companies and adjudication software vendors
to test Year 2000  compliance  in the  industry.  The joint effort is called the
"Y2K  Provider  & Vendor  Testing  Coalition"  and is being  facilitated  by The
National Health Information Network. The coalition has the support of major U.S.
retail pharmacies,  including American Stores, CVS, Eckerd,  Rite-Aid,  Wal-Mart
and  Walgreens.  The  inclusion  of  transaction  routing  vendors and  software
companies could permit up to 95% of the Company's  pharmacy network to be tested
(although  there  can be no  assurance  that  all  parties  who are  invited  to
participate  will  actually  participate).  The program will allocate the retail
pharmacy chains and software vendors among the various PBMs who will be required
to test the vendors' and pharmacy chains' Year 2000  compliance.  The testing is
expected to be completed during the third quarter of 1999.


     The  Company  has  sent  out   approximately   1,500  letters  to  critical
vendor/trading  partners  requesting a status report  regarding  their Year 2000
compliance.  The Company has received  responses from approximately 30% of these
third parties, with the majority of the vendor/trading  partners responding that
they are  currently  addressing  the Year 2000 issue and expect to be compliant.
The  Company is  formulating  a list of  vendor/trading  partners  that have not
responded in order to send second requests.


     The Company has also contacted several hundred clients and several thousand
pharmacies  whose  computer  systems  appear to the  Company not to be Year 2000
compliant  in an effort to increase  awareness  of the  problem and  minimize or
eliminate any disruption in data transfer  activity between such parties and the
Company.  The Company has developed date windowing logic,  which forces an entry
into the century field of a computer  application  if one is not provided by the
user, which it believes will address many issues  concerning  retail  pharmacies
and clients with noncompliant  systems. Due to the Company's contracts typically
extending  over  several  years and the  Company  receiving  member  eligibility
information  from clients that reflect  dates beyond the Year 2000,  the Company
has been receiving  information that would identify certain Year 2000 issues for
several  years.  Any  problems  the  Company has  encountered  to date have been
rectified by the client or, if  necessary,  by the Company  using the  Company's
windowing logic. There can be no assurance, however, that all such problems that
may be encountered in the future can be rectified with the windowing logic.


     In  addressing  the Year 2000 issue,  the Company has and will  continue to
incur  internal  staff costs as well as external  consulting  and other expenses
related to  infrastructure  enhancements.  To date,  the  Company  has  incurred
approximately $3,500,000 addressing the Year 2000 issue. The Company anticipates
spending an additional  $750,000 to $1,000,000  during 1999  addressing the Year
2000 issue.  All  expenditures  are being expensed as incurred.  To date,  these
costs  have not had a  material  adverse  effect  on the  Company's  results  of
operations  or  financial  condition,  and are not  expected  to have a material
adverse  effect on the  Company's  future  results of  operations  or  financial
condition.

     The Company  believes  that,  with  appropriate  modifications  to existing
computer systems,  updates by vendors and trading partners and conversion to new
software  in the  ordinary  course of its  business,  the Year 2000 issue is not
likely to pose significant operational problems for the Company. However, if the
above-described  conversions  are not completed in a proper and timely manner by
all  affected  parties,  or  if  the  Company's  logic  for  communicating  with
noncompliant  systems  is  ineffective,  the Year  2000  issue  could  result in
material adverse  operational and financial  consequences to the Company.  There
can be no assurance that the Company's efforts,  or those of vendors and trading
partners (who are beyond the Company's control) will be successful in addressing
the Year 2000 issue.

     The  Company is in the  process of  formalizing  its  contingency  plans to
address  potential Year  2000-related  risks,  including risks of vendor/trading
partner noncompliance, as well as noncompliance of any of the Company's critical
operations,  and is expected  to be  substantially  completed  by the end of the
second quarter of 1999.  However,  the formalization of the contingency plans is
an ongoing  process as the Company  completes  its testing and receives  updates
from  vendor/trading  partners.  There can be no  assurance  that the  Company's
contingency  plans will  successfully  address all  potential  circumstances  or
consequences.

IMPACT OF INFLATION


         Changes  in  prices  charged  by  manufacturers   and  wholesalers  for
pharmaceuticals affect the Company's net revenues and cost of revenues. To date,
the Company has been able to recover price  increases from its clients under the
terms of its agreements,  although under selected  arrangements in which we have
performance  measurements  on drug costs with our clients,  the Company could be
adversely  affected  by  inflation  in drug  costs if the  result is an  overall
increase  in the cost of the  drug  plan to the  client.  To  date,  changes  in
pharmaceutical prices have not had a significant adverse affect on the Company.


MARKET RISK

     To alleviate  interest rate volatility in connection with its existing $440
million  credit  facility,  the  Company  entered  into an  interest  rate  swap
arrangement for a notional  principal amount of $360 million  effective April 3,
1998,  with First  National  Bank of Chicago.  Under the swap  arrangement,  the
Company  agreed to receive a floating rate of interest on an amount equal to the
outstanding  principal  balance of the term loan portion of the credit  facility
based on a  three-month  LIBOR rate in  exchange  for payment of a fixed rate of
interest of 5.88% per annum on such amount.  The weighted  average variable rate
received by the Company for the period April 3, 1998 to December  31, 1998,  was
5.5729%.  The notional  amount of the swap  amortizes in equal  amounts with the
principal  balance of the term  loan.  The swap  expires  on April 3,  2003.  At
December 31, 1998, the fair value of the swap was ($7,209,000).

     Interest  rate risk is  monitored on the basis of changes in the fair value
and a sensitivity analysis is used to determine the impact interest rate changes
will have on the fair value of the interest  rate swap,  measuring the change in
the net present  value  arising from the change in the interest  rate.  The fair
value of the swap is then  determined  by  calculating  the present value of all
cash-flows  expected  to arise  thereunder,  with  future  interest  rate levels
implied from prevailing mid-market yields for money-market instruments, interest
rate futures and/or prevailing mid-market swap rates. Anticipated cash-flows are
then  discounted on the  assumption of a  continuously  compounding  zero-coupon
yield curve.  A 10% decline in interest  rates at December 31, 1998,  would have
caused  the fair  value of the swap to  decrease  by an  additional  $3,812,000,
resulting in a fair value of ($11,021,000).


Item 7A.  Quantitative and Qualitative Disclosures About Market Risk.

     Response to this item is included in Item 7  "Management's  Discussion  and
Analysis of Financial Condition and Results of Operations--Market Risk" above.


Item 8 - Consolidated Financial Statements and Supplementary Data


                        Report of Independent Accountants


To the Board of Directors and
Stockholders of Express Scripts, Inc.


     In our opinion,  the consolidated  financial statements listed in the index
appearing  under  Item  14(a)(1)  on  page 60  resent  fairly,  in all  material
respects,  the financial position of Express Scripts,  Inc. and its subsidiaries
at December  31, 1998 and 1997,  and the results of their  operations  and their
cash flows for each of the three years in the period ended December 31, 1998, in
conformity with generally accepted accounting  principles.  In addition,  in our
opinion,  the financial  statement  schedule listed in the index appearing under
Item  14(a)(2)  on  page 60  presents  fairly,  in all  material  respects,  the
information  set  forth  therein  when  read in  conjunction  with  the  related
consolidated  financial  statements.  These  financial  statements and financial
statement  schedule are the  responsibility  of the  Company's  management;  our
responsibility  is to  express  an opinion  on these  financial  statements  and
financial  statement  schedule  based on our audits.  We conducted our audits of
these statements in accordance with generally  accepted auditing standards which
require that we plan and perform the audit to obtain reasonable  assurance about
whether the financial  statements  are free of material  misstatement.  An audit
includes  examining,  on a test  basis,  evidence  supporting  the  amounts  and
disclosures in the financial  statements,  assessing the  accounting  principles
used and  significant  estimates made by management,  and evaluating the overall
financial  statement  presentation.   We  believe  that  our  audits  provide  a
reasonable basis for the opinion expressed above.



/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP
St. Louis, Missouri
February 12, 1999



<TABLE>
<CAPTION>

CONSOLIDATED BALANCE SHEET
- -------------------------------------------------------------------------------
                                                                                               DECEMBER 31,
(IN THOUSANDS, EXCEPT SHARE DATA)                                                       1998                1997
<S>                                                                                   <C>               <C>
- ----------------------------------------------------------------------------------------------------------------------
Assets
Current assets:
    Cash and cash equivalents                                                         $     122,589     $        64,155
    Short-term investments                                                                                       57,938
    Receivables, less allowance for doubtful
        accounts of $17,806 and $4,802, respectively
            Unrelated parties                                                               433,006             194,061
            Related parties                                                                                      16,230
    Inventories                                                                              55,634              28,935
    Deferred taxes                                                                           41,011               2,303
    Prepaid expenses                                                                          4,667                 346
                                                                                  --------------------------------------
            Total current assets                                                            656,907             363,968
                                                                                  --------------------------------------
Property and equipment, less accumulated depreciation and amortization                       77,499              26,821
Goodwill, less accumulated amortization                                                     282,163                 251
Other assets                                                                                 78,892              11,468
                                                                                  -------------------------------------
            Total assets                                                               $  1,095,461       $     402,508
                                                                                  =====================================

Liabilities and Stockholders' Equity Current liabilities:
    Current maturities of long-term debt                                             $       54,000       $           -
    Claims and rebates payable                                                              338,251             164,920
    Accounts payable                                                                         60,247              17,979
    Accrued expenses                                                                         86,798              15,007
                                                                                  -------------------------------------
            Total current liabilities                                                       539,296             197,906
Long-term debt                                                                              306,000
Other liabilities                                                                               471                 901
                                                                                  --------------------------------------
    Total liabilities                                                                       845,767             198,807
                                                                                  --------------------------------------

Commitments and Contingencies (Notes 3, 9 and 15)

Stockholders' equity:
    Preferred stock, $.01 par value, 5,000,000 shares
        authorized, and no shares issued and outstanding
    Class A Common Stock, $.01 par value, 75,000,000 shares authorized,
        18,610,000 and 9,238,000 shares issued and outstanding, respectively                    186                  93
    Class B Common Stock, $.01 par value, 22,000,000 shares authorized,
        15,020,000 and 7,510,000 shares issued and outstanding, respectively                    150                  75
    Additional paid-in capital                                                              110,099             106,901
    Accumulated other comprehensive income                                                     (74)                (27)
    Retained earnings                                                                       146,322             103,648
                                                                                  -------------------------------------
                                                                                            256,683             210,690
    Class A Common Stock in treasury at cost, 475,000 shares                                (6,989)             (6,989)
                                                                                  -------------------------------------
            Total stockholders' equity                                                      249,694             203,701
                                                                                  -------------------------------------
            Total liabilities and stockholders' equity                                 $  1,095,461        $    402,508
                                                                                  =====================================

</TABLE>

SEE ACCOMPANYING NOTES TO CONSOLIDATED FINANCIAL STATEMENTS.


<PAGE>


CONSOLIDATED STATEMENT OF OPERATIONS
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                       YEAR ENDED DECEMBER 31,
(IN THOUSANDS, EXCEPT PER SHARE DATA)                                1998                1997               1996
<S> <C>                                                              <C>                 <C>                <C>

- ------------------------------------------------------------------------------------------------------------------------
Net revenues (including $145,758, $208,118 AND
    $152,311, respectively,from related parties)                     $ 2,824,872         $ 1,230,634        $   773,615
                                                              ----------------------------------------------------------
Cost and expenses:
    Cost of revenues (including $127,255, $176,761
    and $122,157, respectively, to related Parties)                    2,584,997           1,119,167            684,882
    Selling, general and administrative                                  148,990              62,617             49,103
    Corporate restructuring                                                1,651                   -                  -
                                                              ----------------------------------------------------------

                                                                       2,735,638           1,181,784            733,985
                                                              ----------------------------------------------------------
Operating income                                                          89,234              48,850             39,630
                                                              ----------------------------------------------------------
Interest income (expense):
    Interest income                                                        7,236               6,081              3,509
    Interest expense                                                    (20,230)               (225)               (59)
                                                              ----------------------------------------------------------
                                                                        (12,994)               5,856              3,450
                                                              ----------------------------------------------------------
Income before income taxes                                                76,240              54,706             43,080
Provision for income taxes                                                33,566              21,277             16,932
                                                              ----------------------------------------------------------
Net income                                                         $      42,674       $      33,429       $     26,148
                                                              ==========================================================
Basic earnings per share                                           $        1.29       $        1.02       $       0.81
                                                              ==========================================================
Weighted average number of common shares
    outstanding during the period - Basic EPS                             33,105              32,713             32,160
                                                              ==========================================================


Diluted earnings per share                                        $         1.27       $        1.01       $       0.80
                                                              ==========================================================
Weighted average number of common shares outstanding
    during the period - Diluted EPS                                       33,698              33,122             32,700
                                                              ==========================================================
</TABLE>

SEE ACCOMPANYING NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


<PAGE>


CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY

<TABLE>
<CAPTION>
                            Number of Shares                                   Amount
                          -------------------    ----------------------------------------------------------------------------------
                                                                                   Accumulated
                          Class A    Class B      Class A    Class B   Additional    Other
                          Common     Common       Common     Common      Paid-in  Comprehensive   Retained    Treasury
(IN THOUSANDS)            Stock       Stock        Stock      Stock      Capital     Income       Earnings      Stock      Total
<S>                          <C>       <C>        <C>       <C>         <C>        <C>
- ----------------------------------------------    ---------------------------------------------------------------------------------
Balance at December 31,
1995                         4,539     10,500     $     45  $    105    $33,158    $    -        $  44,071        -      $  77,379
                          --------------------    ---------------------------------------------------------------------------------
 Comprehensive income:
    Net income                                                                                      26,148                  26,148
    Other comprehensive
      income,
        Foreign currency
          translation
          adjustment             -          -            -          -         -          (2)            -           -          (2)
                          --------------------    ---------------------------------------------------------------------------------
 Comprehensive income            -          -            -          -         -          (2)        26,148          -       26,146
    Conversion of Class B
     Common Stock to
     Class A Common Stock     2,990    (2,990)           30       (30)
 Issuance of Class A
    Common Stock
     Contractual agreement      227                       2              11,250                                             11,252
     Public offering          1,150                      12              52,580                                             52,592
 Exercise of stock options       68                       1               1,309                                              1,310
 Tax benefit relating to
    employee stock options                                                  661                                                661
 Treasury Stock acquired         -          -            -          -         -            -         -           (5,250)   (5,250)
                          -------------------    ---------------------------------------------------------------------------------
Balance at December 31,
 1996                         8,974     7,510            90         75   98,958          (2)        70,219       (5,250)   164,090
                          -------------------    ---------------------------------------------------------------------------------
 Comprehensive income:
    Net income                                                                                      33,429                  33,429
    Other comprehensive
     income,
       Foreign currency
        translation
        adjustment               -          -            -           -        -         (25)          -              -        (25)
                           -------------------   ---------------------------------------------------------------------------------
Comprehensive income             -          -            -           -        -         (25)        33,429           -      33,404
   Exercise of stock
    options                     264                       3               4,769                                              4,772
   Tax benefit relating
    to employee stock
    options                                                               3,174                                              3,174
   Treasury Stock acquired       -          -            -           -        -            -          -          (1,739)   (1,739)
                          --------------------   ---------------------------------------------------------------------------------
Balance at December 31,
1997                          9,238      7,510           93         75  106,901         (27)       103,648       (6,989)   203,701
                          --------------------   ---------------------------------------------------------------------------------
Comprehensive income:
   Net income                                                                                       42,674                  42,674
   Other comprehensive
    income,
     Foreign currency
      translation
       adjustmenty               -          -            -          -         -         (47)          -             -         (47)
                          --------------------   ---------------------------------------------------------------------------------
Comprehensive income             -          -            -          -         -         (47)        42,674          -       42,627
Issuance of stock
   dividend                   9,239      7,510           92         75    (167)
Exercise of stock
   options                      133                       1               2,020                                              2,021
Tax benefit relating to
   employee stock options        -          -             -          -    1,345            -          -             -        1,345
                          --------------------   ---------------------------------------------------------------------------------
Balance at December 31,
1998                         18,610     15,020    $     186   $    150 $110,099         (74)       146,322        (6,989)  249,694
                          ====================    ================================================================================

</TABLE>

SEE ACCOMPANYING NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


<PAGE>


CONSOLIDATED STATEMENT OF CASH FLOWS
<TABLE>
<CAPTION>

                                                                         YEAR ENDED DECEMBER 31,
(IN THOUSANDS)                                                          1998                1997               1996
<S>                                                                 <C>                 <C>                <C>
- -----------------------------------------------------------------------------------------------------------------------
 Cash flows from operating activities:
    Net income                                                      $     42,674        $     33,429       $     26,148
    Adjustments to reconcile net income to net
    cash provided by operating activities:
        Depreciation and amortization                                     27,042              10,470              6,707
        Deferred income taxes                                             10,068               (834)                317
        Bad debt expense                                                   4,583               3,680              1,456
        Corporate restructuring, less cash payments of $184                1,467
        Tax benefit relating to employee stock options                     1,345               3,174                661
        Changes in operating assets and liabilities, net of
          changes resulting from acquisition:
            Receivables                                                 (35,083)            (50,166)           (48,149)
            Inventories                                                 (15,417)            (11,444)            (3,638)
            Prepaid expenses and other assets                                756               1,722            (3,104)
            Claims and rebates payable                                   107,660              57,968             41,055
            Accounts payable and accrued expenses                       (18,521)               4,504              8,410
                                                              ---------------------------------------------------------
Net cash provided by operating activities                                126,574              52,503             29,863
                                                              ---------------------------------------------------------

Cash flows from investing activities:
    Acquisitions, net of cash acquired                                 (460,137)                                  (940)
    Short-term investments                                                57,938             (3,550)           (54,388)
    Purchases of property and equipment                                 (23,853)            (13,017)            (9,480)
                                                              ---------------------------------------------------------
Net cash (used in) investing activities                                (426,052)            (16,567)           (64,808)
                                                              ---------------------------------------------------------

Cash flows from financing activities:
    Proceeds on long-term debt                                           360,000                   -                  -
    Proceeds from stock offering                                                                                 52,592
    Deferred financing fees                                              (4,062)
    Acquisition of treasury stock                                                            (1,739)            (5,250)
    Exercise of stock options                                              2,021               4,772              1,310
                                                              ---------------------------------------------------------
Net cash provided by financing activities                                357,959               3,033             48,652
                                                              ---------------------------------------------------------

Effect of foreign currency translation adjustment                           (47)                (25)                (2)
                                                              ---------------------------------------------------------

Net increase in cash and cash equivalents                                 58,434              38,944             13,705
Cash and cash equivalents at beginning of year                            64,155              25,211             11,506
                                                              =========================================================
Cash and cash equivalents at end of year                             $   122,589        $     64,155       $     25,211
                                                              =========================================================
Supplemental data:
Cash paid during the year for:
    Income taxes                                                    $     17,202        $     20,691       $     14,544
    Interest                                                        $     13,568      $          225    $            59

</TABLE>

SEE ACCOMPANYING NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

<PAGE>


NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

- -------------------------------------------------------------------------------

1.       Summary of significant accounting policies


     Organization  and operations.  Express  Scripts,  Inc. (the "Company") is a
leading  specialty  managed care company and  (subsequent to its  acquisition of
Value Health, Inc. and Managed Prescription  Network, Inc. on April 1, 1998, see
Note 2) is the largest full-service  pharmacy benefit management ("PBM") company
independent of pharmaceutical manufacturer ownership and drug store ownership in
North America.  The Company  provides health care management and  administration
services on behalf of  thousands  of clients  that  include  health  maintenance
organizations,  health  insurers,  third-party  administrators,   employers  and
union-sponsored  benefit  plans.  The  Company's  fully-integrated  PBM services
include  network  claims  processing,  mail pharmacy  services,  benefit  design
consultation, drug utilization review, formulary management, disease management,
medical  and  drug  data  analysis  services,   medical  information  management
services,  which include provider profiling and outcome  assessments through its
majority-owned Practice Patterns Science, Inc. ("PPS") subsidiary,  and informed
decision  counseling  services through its Express Health LineSM  division.  The
Company also provides  non-PBM  services which include infusion therapy services
through its wholly-owned  subsidiary IVTx, Inc. ("IVTx"),  distribution services
through its Specialty  Distribution  division,  and, prior to September 1, 1998,
provided  managed  vision  care  programs  through its  wholly-owned  subsidiary
Express Scripts Vision Corporation ("Vision").


     In March 1992, the Company,  originally  incorporated  in Missouri in 1986,
was  reincorporated  in Delaware and issued an aggregate of 21,000,000 shares of
Class B Common Stock to Sanus Corp. Health Systems ("Sanus") in exchange for the
outstanding  shares of its  common  stock.  Sanus at that  time was an  indirect
subsidiary  of New York Life  Insurance  Company  ("NYL").  In April 1992,  as a
result  of  a   reorganization,   both  the  Company  and  Sanus  became  direct
subsidiaries of NYLIFE HealthCare Management,  Inc. ("NYLIFE").  Sanus has since
changed  its name to NYLCare  Health  Plans,  Inc.  ("NYLCare").  In April 1996,
NYLIFE converted 5,980,000 Class B shares to Class A Common Stock and sold those
shares  in a  public  offering.  NYLIFE  continues  to  own  all  the  remaining
outstanding Class B Common Stock of the Company (see Note 11).

     Basis of presentation. The consolidated financial statements include
the   accounts  of  the  Company  and  all   wholly-owned   and   majority-owned
subsidiaries.  All significant  intercompany accounts and transactions have been
eliminated.  Certain  amounts in prior years have been  reclassified  to conform
with  1998  classifications.  The  preparation  of  the  consolidated  financial
statements  conform to generally  accepted  accounting  principles,  and require
management to make estimates and assumptions that affect the reported amounts of
assets and liabilities at the date of the financial  statements and the reported
amounts of revenues and expenses  during the reporting  period.  Actual  amounts
could differ from those estimates and assumptions.

     Cash and cash equivalents. Cash and cash equivalents include cash on
hand and temporary investments in money market funds.

     Short-term investments. Short-term investments consisted of debt securities
with a maturity of less than one year that the Company had the  positive  intent
and ability to hold to maturity and are reported at amortized cost.

     Inventories. Inventories consist of prescription drugs, vision supplies and
medical  supplies  that are stated at the lower of  first-in  first-out  cost or
market.

     Property and  equipment.  Property and  equipment is carried at cost and is
depreciated using the straight-line  method over estimated useful lives of seven
years for furniture,  five years for equipment and purchased  computer  software
and three years for personal computers.  Leasehold improvements are amortized on
a  straight-line  basis  over the term of the  lease or the  useful  life of the
asset,  if shorter.  Expenditures  for  repairs,  maintenance  and  renewals are
charged to income as incurred. Expenditures which improve an asset or extend its
estimated useful life are capitalized.  When properties are retired or otherwise
disposed of, the related cost and accumulated  depreciation are removed from the
accounts and any gain or loss is included in income.


     Software   development  costs.  During  1997,  the  Company  early  adopted
Statement of Position  98-1 ("SOP 98-1"),  Accounting  for the Costs of Computer
Software  Developed  or  Obtained  for  Internal  Use.  SOP  98-1  requires  the
capitalization of certain costs associated with computer  software  developed or
obtained for internal use. Given the limited software  developed or obtained for
internal  use in  1997,  adoption  had  virtually  no  effect  on the  Company's
Consolidated  Statement of Operations or its financial  position.  However,  the
impact of SOP 98-1 on an ongoing  basis will be  determined  by the magnitude of
computer  software   developed  or  obtained  for  internal  use.  Research  and
development  expenditures relating to the development of software to be marketed
to clients,  or to be used for internal  purposes,  are charged to expense until
technological  feasibility is established.  Thereafter,  the remaining  software
production costs up to the date of general release to customers,  or to the date
placed into production,  are capitalized and included as Property and Equipment.
During 1998, 1997 and 1996,  $10,244,000,  $1,982,000 and $1,898,000 in software
development  costs  were   capitalized,   respectively.   Capitalized   software
development  costs amounted to  $27,516,000  and $5,269,000 at December 31, 1998
and 1997, respectively. Amortization of the capitalized amounts commences on the
date of general release to customers, or the date placed into production, and is
computed on a  product-by-product  basis using the straight-line method over the
remaining  estimated  economic life of the product but not more than five years.
Reductions,  if any, in the carrying value of capitalized  software costs to net
realizable value are also included in amortization expense. Amortization expense
in 1998, 1997 and 1996 was $1,968,000, $622,000 and $136,000, respectively.


     Goodwill.  Goodwill is amortized on a straight-line basis over periods from
15 to 30 years.  The  amount  reported  is net of  accumulated  amortization  of
$8,114,000 and $251,000 at December 31, 1998 and 1997, respectively. The Company
periodically  evaluates  the  carrying  value of goodwill  for  impairment.  The
evaluation of impairment is based on expected future  operating cash flows on an
undiscounted  basis for the  operations to which  goodwill  relates.  Impairment
losses, if any, would be determined based on the present value of the cash flows
using discount rates that reflect the inherent risk of the underlying  business.
In the opinion of management, no such impairment existed at December 31, 1998 or
1997.  Amortization  expense,  included in selling,  general and  administrative
expenses,  was $7,863,000,  $42,000 and $42,000 for the years ended December 31,
1998, 1997 and 1996, respectively.

     Other intangible assets. Other intangible assets (included in other assets)
consist of customer  contracts,  non-compete  agreements and deferred  financing
fees and are amortized on a straight-line basis over periods from 2 to 20 years.
Amortization expense for customer contracts and non-compete agreements, included
in selling,  general and  administrative  expenses,  and for deferred  financing
fees, included in interest expense,  was $4,320,000 and $609,000,  respectively,
for the year ended December 31, 1998.

     Contractual  agreements.  The Company has entered into corporate  alliances
with certain of its clients whereby shares of the Company's Class A Common Stock
were awarded as advance discounts to the clients. The Company accounts for these
agreements as follows:

     Prior to December 15, 1995 - For agreements  consummated  prior to December
15, 1995, the stock is valued  utilizing the quoted market value at the date the
agreement is consummated  if the number of shares to be issued is known.  If the
number  of  shares to be issued  is  contingent  upon the  occurrence  of future
events,  the stock is valued  utilizing  the quoted market value at the date the
contingency is satisfied and the number of shares is determinable.

     Between  December 15, 1995 and November 20, 1997 - For  agreements  entered
into between  these dates,  the Company  utilizes  the  provisions  of Financial
Accounting   Standards   Board   Statement  123   "Accounting   for  Stock-Based
Compensations"  ("FAS 123") which requires that all stock issued to nonemployees
be accounted  for based on the fair value of the  consideration  received or the
fair value of the equity  instruments  issued  instead  of the  intrinsic  value
method  utilized for stock issued or to be issued under  alliances  entered into
prior to  December  15,  1995.  The Company has adopted FAS 123 as it relates to
stock issued or to be issued under the Premier and Manulife  alliances  based on
fair value at the date the agreement was consummated.

     Subsequent  to November 20, 1997 - In November  1997,  the Emerging  Issues
Task Force reached a consensus that the value of equity  instruments  issued for
consideration other than employee services should be initially determined on the
date on which a "firm  commitment" for performance  first exists by the provider
of goods or services.  Firm  commitment  is defined as a commitment  pursuant to
which  performance  by a provider of goods or  services  is probable  because of
sufficiently  large  disincentives  for  nonperformance.  The consensus  must be
applied for all new  arrangements  and  modifications  of existing  arrangements
entered into from November 20, 1997.  The consensus only addresses the date upon
which fair value is  determined  and does not change the  accounting  based upon
fair value as prescribed by FAS 123. No such arrangements have been entered into
by the Company subsequent to November 20, 1997.

     Shares  issued  on the  effective  date of the  contractual  agreement  are
considered  outstanding  and  included in basic and diluted  earnings  per share
computations  when issued.  Shares  issuable  upon the  satisfaction  of certain
conditions  are  considered  outstanding  and  included  in basic  and  dilutive
earnings per share computation when all necessary conditions have been satisfied
by the end of the period. If all necessary conditions have not been satisfied by
the end of the period,  the number of shares  included in the dilutive  earnings
per share  computation  is based on the number of shares,  if any, that would be
issuable  if the end of the  reporting  period  were the end of the  contingency
period and if the  result  would be  dilutive.  The value of the shares of stock
awarded as advance  discounts  is  recorded as a deferred  cost and  included in
other  assets.  The  deferred  cost  is  recognized  in  selling,   general  and
administrative expenses over the period of the contract.


     Impairment of long lived assets.  The Company  evaluates whether events and
circumstances have occurred that indicate the remaining estimated useful life of
long lived assets may warrant revision or that the remaining balance of an asset
may not be recoverable.  The measurement of possible  impairment is based on the
ability to recover the balance of assets from  expected  future  operating  cash
flows on an undiscounted  basis.  Impairment losses, if any, would be determined
based on the present value of the cash flows using  discount  rates that reflect
the inherent risk of the underlying business.  In the opinion of management,  no
such  impairment  existed  as of  December  31,  1998 or  1997,  except  for the
write-down of the long-lived  assets of Express Scripts Vision  Corporation (see
Note 7).


     Derivative financial instruments.  The Company has entered into an interest
rate swap  agreement  in order to manage  exposure  to interest  rate risk.  The
Company  does not hold or issue  derivative  financial  instruments  for trading
purposes.  The  interest  rate swap is  designated  as a hedge of the  Company's
variable  interest  rate  payments.  Amounts  received  or paid are  accrued  as
interest receivable or payable and as interest income or expense. The fair value
of  interest  rate swap  agreements  is based on market  prices.  The fair value
represents the estimated  amount the Company would  receive/pay to terminate the
agreements taking into consideration current interest rates.

     In June 1998, the Financial  Accounting Standards Board ("the FASB") issued
Statement of Financial  Accounting Standards No. 133, "Accounting for Derivative
Instruments  and Hedging  Activities"  ("FAS 133").  The Statement  requires all
derivatives  be recognized as either assets or  liabilities  in the statement of
financial position and measure those instruments at fair value. In addition, the
Statement specifies the accounting for changes in the fair value of a derivative
based on the intended use of the derivative and the resulting  designation.  FAS
133 is effective for all fiscal  quarters of fiscal years  beginning  after June
15, 1999 and will be applicable  to the  Company's  first quarter of fiscal year
2000. The Company's  present interest rate swap (see Note 6) would be considered
a cash flow hedge.  Accordingly,  the change in the fair value of the swap would
be reported on the balance  sheet as an asset or  liability.  The  corresponding
unrealized gain or loss  representing the effective portion of the hedge will be
initially recognized in stockholders' equity and other comprehensive income, and
subsequently any changes in unrealized gain or loss from the initial measurement
date will be recognized in earnings  concurrent with the interest expense on the
Company's  underlying  variable rate debt. If the Company had adopted FAS 133 as
of December 31, 1998, the Company would record the unrealized loss of $7,209,000
as a liability and  reduction in  stockholder's  equity and other  comprehensive
income.

     Fair value of financial  instruments.  The carrying  value of cash and cash
equivalents,  short-term  investments,  accounts receivable and accounts payable
approximated fair values due to the short-term  maturities of these instruments.
The fair value,  which  approximates  the carrying  value, of the Company's term
loan  facility was  estimated  using either  quoted market prices or the current
rates offered to the Company for debt with similar  maturity.  The fair value of
the swap ($7,209,000  liability at December 31, 1998) was based on quoted market
price,  which  reflects the present value of the  difference  between  estimated
future fixed rate payments and future variable rate receipts.

     Revenue   recognition.    Revenues   from   dispensing   prescription   and
non-prescription medical products from the Company's mail service pharmacies are
recorded upon shipment.  Revenue from sales of prescription  drugs by pharmacies
in the Company's  nationwide network and pharmacy claims processing revenues are
recognized   when  the  claims  are  processed.   When  the  Company   dispenses
pharmaceuticals  to members of health  benefit plans  sponsored by the Company's
clients or has an independent contractual obligation to pay its network pharmacy
providers  for  benefits  provided to members of its clients'  pharmacy  benefit
plans,  the Company  includes  payments from plan sponsors for these benefits as
net revenue and ingredient costs or payments to these pharmacy providers in cost
of revenues.  If the Company is only  administering  the plan sponsors'  network
pharmacy contracts, or where the Company dispenses  pharmaceuticals  supplied by
one of the Company's  clients,  the Company records only the  administrative  or
dispensing  fees derived from the Company's  contracts with the plan sponsors as
net revenue.


     Client  revenue is recognized  based upon actual  scripts  adjudicated  and
therefore  requires no estimation.  Amounts remain  unbilled for no more than 30
days based upon the  contractual  billing  schedule  agreed with the client.  At
December  31,  1998  and  1997,  unbilled   receivables  were  $209,334,000  and
$96,644,000, respectively.

     Cost of revenues.  Cost of revenues includes product costs, pharmacy claims
payments and other direct costs  associated  with dispensing  prescriptions  and
non-prescription  medical products and claims processing  operations,  offset by
fees received from pharmaceutical manufacturers in connection with the Company's
drug purchasing and formulary  management  programs.  The Company estimates fees
receivable from  pharmaceutical  manufacturers  on a quarterly basis  converting
total  prescriptions  dispensed  to estimated  rebatable  scripts  (i.e.,  those
prescriptions  with  respect to which the Company is  contractually  entitled to
submit claims for rebates)  multiplied by the contractually  agreed manufacturer
rebate amount.  Estimated fees receivable from pharmaceutical  manufacturers are
recorded when determined by management to be realizable,  and realization is not
dependent  upon future  pharmaceutical  sales.  Estimates  are revised  once the
actual  rebatable   scripts  are  calculated  and  rebates  are  billed  to  the
manufacturer.


     Income taxes.  Deferred tax assets and liabilities are recognized  based on
temporary  differences between financial statement basis and tax basis of assets
and liabilities using presently enacted tax rates.

     Earnings per share. Basic earnings per share is computed using the weighted
average number of common shares outstanding during the period.  Diluted earnings
per share is computed in the same  manner as basic  earnings  per share but adds
the number of additional  common shares that would have been outstanding for the
period  if the  dilutive  potential  common  shares  had been  issued.  The only
difference  between the number of weighted  average shares used in the basic and
diluted calculation for all years is stock options and stock warrants granted by
the Company using the "treasury stock" method, amounting to 593,000, 409,000 and
540,000 in 1998, 1997 and 1996, respectively.

     Foreign currency translation.  The financial statements of ESI Canada, Inc.
are translated  into U.S.  Dollars using the exchange rate at each balance sheet
date for assets and  liabilities and a weighted  average  exchange rate for each
period for revenues, expenses, gains and losses. The functional currency for ESI
Canada,  Inc. is the local  currency and  translation  adjustments  are recorded
within the other comprehensive income component of stockholders' equity.

     Employee stock-based compensation.  The Company accounts for employee stock
options  in  accordance  with  Accounting  Principles  Board No. 25 ("APB  25"),
"Accounting  for Stock Issued to Employees."  Under APB 25, the Company  applies
the intrinsic  value method of  accounting  and,  therefore,  does not recognize
compensation expense for options granted,  because options are only granted at a
price equal to market value at the time of grant.  During  1996,  FAS 123 became
effective for the Company.  FAS 123 prescribes the  recognition of  compensation
expense  based on the fair  value  of  options  determined  on the  grant  date.
However,  FAS 123 grants an exception that allows companies  currently  applying
APB 25 to continue  using that method.  The Company has,  therefore,  elected to
continue  applying the intrinsic  value method under APB 25. For companies  that
choose to continue applying the intrinsic value method, FAS 123 mandates certain
pro forma  disclosures  as if the fair value method had been  utilized (see Note
12).

     Comprehensive  income.  During  1998,  Statement  of  Financial  Accounting
Standards  No.  130  ("FAS  130"),  "Reporting   Comprehensive  Income,"  became
effective for the Company.  FAS 130 requires  noncash  changes in  stockholders'
equity be combined  with net income and  reported in a new  financial  statement
category  entitled  "comprehensive  income."  Other  than net  income,  the only
component of  comprehensive  income for the Company is the change in the foreign
currency translation adjustment.  The Company has displayed comprehensive income
within the Statement of Changes in Stockholders' Equity.

     Segment  reporting.  In June 1997,  the FASB issued  Statement of Financial
Accounting  Standards No. 131,  "Disclosures about Segments of an Enterprise and
Related  Information"  ("FAS  131").  FAS 131 requires  that the Company  report
certain information,  if specific requirements are met, about operating segments
of the  Company  including  information  about  services,  geographic  areas  of
operation  and  major  customers.  The  information  is to be  derived  from the
management  approach which designates the internal  organization that is used by
management  for making  operating  decisions  and assessing  performance  as the
source of the Company's reportable segments.  Adoption of FAS 131 did not affect
the Company's results of operations or its financial position but did affect the
disclosure of segment information (see Note 13).

2.       Acquisition

     On April 1, 1998 the Company acquired all of the outstanding  capital stock
of Value Health, Inc. and Managed Prescriptions Network, Inc. (collectively, the
"Acquired Entities") from Columbia/HCA  Healthcare Corporation  ("Columbia") for
approximately  $460  million  in cash  (which  includes  transactions  costs and
executive  management  severance  costs of  approximately  $6.7 million and $8.3
million, respectively), approximately $360 million of which was obtained through
a  five-year  bank  credit  facility  (see  Note 6) and the  remainder  from the
Company's  cash balances and short term  investments.  At closing,  the Acquired
Entities  owned  various  subsidiaries  that  now or  formerly  conducted  a PBM
business, commonly known as "ValueRx".

     The  acquisition  has been  accounted  for  using  the  purchase  method of
accounting  and the results of  operations  of the Acquired  Entities  have been
included in the consolidated financial statements and PBM segment since April 1,
1998. The purchase price has been preliminarily allocated based on the estimated
fair values of net assets acquired at the date of the acquisition. The excess of
purchase  price over tangible net assets  acquired was  originally  allocated to
other  intangible  assets  consisting  of  customer  contracts  and  non-compete
agreements  in the amount of  $57,653,000  which are being  amortized  using the
straight-line  method over the  estimated  useful lives of 2 to 20 years and are
included in other assets,  and goodwill in the amount of  $289,863,000  which is
being amortized using the straight-line method over the estimated useful life of
30 years. In conjunction with the acquisition,  the Acquired  Entities and their
subsidiaries retained the following liabilities:

<TABLE>
<CAPTION>
(in thousands)
- --------------------------------------------------------------------------------
<S>                                                  <C>
Fair value of assets acquired                        $    656,488
Cash paid for the capital stock                         (460,137)
                                           =======================
          Liabilities retained                       $    196,351
                                           =======================
</TABLE>

     The  following  unaudited  pro forma  information  presents  a  summary  of
combined  results of operations  of the Company and the Acquired  Entities as if
the  acquisition  had occurred at the beginning of the period  presented,  along
with certain pro forma  adjustments to give effect to  amortization of goodwill,
other  intangible  assets,  interest  expense  on  acquisition  debt  and  other
adjustments.  The pro forma financial information is not necessarily  indicative
of the results of  operations as they would have been had the  transaction  been
effected  on the  assumed  dates.  Included  in the pro  forma  information  are
integration  costs  incurred  by the  Company  that are  being  reported  within
selling, general and administrative expenses in the statement of operations.

<TABLE>
<CAPTION>
                                                    Year Ended December 31,
(in thousands, except per share data)            1998                    1997
- --------------------------------------------------------------------------------
<S>                                               <C>              <C>
Net revenues                                      $3,234,800       $2,877,906
Net income                                            42,696           33,687
Basic earnings per share                                1.29             1.03
Diluted earnings per share                              1.27             1.02
</TABLE>

3.       Contractual agreements


     On  December  31,  1995,  the  Company  entered  into a ten-year  corporate
alliance with Premier Purchasing Partners,  L.P. (formerly,  American Healthcare
Systems Purchasing Partners, L.P., the "Partnership"),  an affiliate of Premier,
Inc.  ("Premier").  Premier is an alliance of health care systems resulting from
the merger in 1995 of American Healthcare  Systems,  Premier Health Alliance and
SunHealth Alliance. Under the terms of the transaction, the Company is Premier's
preferred   vendor  of  pharmacy  benefit   management   services  to  Premier's
shareholder  systems and their managed care  affiliates and will issue shares of
its Class A Common Stock as an  administrative  fee to the Partnership  based on
the  attainment  of  certain  benchmarks,  principally  related to the number of
members receiving the Company's pharmacy benefit  management  services under the
arrangement,  and to the  achievement  of certain joint  purchasing  goals.  The
Company may be required to issue up to 4,500,000  shares to the Partnership over
a period up to the first five years of the agreement if the Partnership  exceeds
all  benchmarks.  Except for  certain  exemptions  from  registration  under the
Securities  Act of 1933 ("the 1933 Act"),  any shares issued to the  Partnership
cannot be traded  until  they  have been  registered  under the 1933 Act and any
applicable state securities laws.

     In accordance  with the terms of the agreement,  the Company issued 454,546
shares of Class A Stock to  Premier in May,  1996.  The  shares  were  valued at
$11,250,000  using the Company's  closing stock price on December 31, 1995,  the
date the  agreement  was  consummated,  and are  being  amortized  over the then
remaining term of the agreement. Amortization expense in 1998, 1997 and 1996 was
$1,164,000,  $1,164,000 and $776,000,  respectively.  No additional  shares have
been earned by Premier through December 31, 1998.


     Effective January 1, 1996, the Company executed a multi-year  contract with
The Manufacturers  Life Insurance Company  ("Manulife"),  to introduce  pharmacy
benefit  management  services  in Canada.  Manulife's  Group  Benefits  Division
continues to work with ESI Canada to provide these services.  Under the terms of
the  agreement,  the Company is the exclusive  third-party  provider of pharmacy
benefit  management  services to Manulife's  Canadian clients.  The Company also
will issue shares of its Class A Common Stock as an advance discount to Manulife
based upon achievement of certain volumes of Manulife  pharmacy claims processed
by the  Company.  No shares  will be issued  until  after the fourth year of the
agreement  based on  volumes  reached in years two  through  four.  The  Company
anticipates  issuing no more than 474,000 shares to Manulife over a period up to
the  first  six years of the  agreement.  Except  for  certain  exemptions  from
registration  under the 1933 Act, any shares issued to Manulife cannot be traded
until  they have been  registered  under the 1933 Act and any  applicable  state
securities  laws. In accordance  with the terms of the  agreement,  no stock has
been issued since inception.

     If Manulife has not exercised an early termination option at the end of the
sixth or tenth year of the  agreement,  the Company  will issue at each of those
times a ten-year  warrant as an advance discount to purchase up to approximately
237,000  additional  shares of the Company's Class A Common Stock exercisable at
85% of the market  price at those times.  The actual  number of shares for which
such warrant is to be issued is based on the volume of Manulife  pharmacy claims
processed by the Company in year six and year ten, respectively.


     Pursuant to an agreement with Coventry  Corporation,  an operator of health
maintenance  organizations  located principally in Pennsylvania and Missouri, on
January 3, 1995,  the Company issued 50,000 shares of Class A Common Stock as an
advance discount to Coventry in a private placement. These shares were valued at
$13.69 per share,  the  split-adjusted  per share market value of the  Company's
Class A Common Stock on November 22, 1994,  which was the date the agreement was
consummated and the obligation of the parties became unconditional.  No revision
of the consideration for the transaction  occurred between November 22, 1994 and
January 3, 1995.  The shares  issued to  Coventry  were being  amortized  over a
six-year period.  However,  due to Coventry extending the agreement for only two
years, as discussed below,  instead of three years, the estimated useful life of
the shares  issued has been  reduced to five  years.  Amortization  expense  was
$171,000,  $114,000 and $114,000 for each of the years ended  December 31, 1998,
1997 and 1996,  respectively.  Except for certain  exemptions from  registration
under  the 1993  Act,  these  shares  cannot  be  traded  until  they  have been
registered under the 1933 Act and any applicable state securities laws.


     Effective  January 1, 1998,  Coventry  renewed the agreement for a two-year
term through  December 31, 1999. As part of the  agreement,  the Company  issued
warrants as an advance  discount to purchase an additional  50,000 shares of the
Company's  Class A Common Stock,  exercisable  at 90% of the market value at the
time of renewal.  During 1998, the Company  expensed the advance  discount which
represented 10% of the market value.

     On October 13, 1992, the Company entered into a five-year  arrangement with
FHP,  Inc.  ("FHP")  pursuant  to which the Company  agreed to provide  pharmacy
benefit  services  to  FHP  and  its  members.  FHP  is an  operator  of  health
maintenance organizations, principally in the western United States. In February
1997, PacifiCare Health Systems, Inc.  ("PacifiCare")  completed the acquisition
of FHP. As a result of the merger, PacifiCare informed the Company that it would
not enter into a long-term  extension of the  agreement and reached an agreement
with the Company to  phase-out  membership  starting in July 1997 and  continued
through March 1998.

     In accordance with the agreement,  the Company commenced providing pharmacy
benefit  services to FHP and its members on January 4, 1993. On the commencement
date and pursuant to the  agreement,  the Company  issued  400,000 shares of its
Class A Common Stock as advance discounts to FHP in a private  placement.  These
shares were valued at $4.13 per share, the split-adjusted per share market value
of the  Company's  Class A shares on October  13,  1992,  which was the date the
agreement  was   consummated   and  the   obligations   of  the  parties  became
unconditional.  No revision of the  consideration  for the transaction  occurred
between  October 13, 1992 and January 4, 1993.  The cost of the shares issued to
FHP was  amortized  over a  five-year  period  ending in 1997.  No  amortization
expense was  recorded  in 1998.  Amortization  expense was  $990,000 in 1997 and
$165,000 in 1996.

4.       Related party transactions


         The Company had  agreements to provide claims  processing  services and
mail pharmacy prescription services for NYLCare, in return for which it receives
processing  fees  and  reimbursement  for the  contracted  cost  of the  claims.
Effective  July 15,  1998,  NYL  consummated  the sale of  NYLCare to Aetna U.S.
Healthcare,  Inc., an unrelated party. Therefore, related party amounts for 1998
represent only the period in which NYL owned NYLCare. Transactions subsequent to
July 15, 1998 have been included in unrelated parties.


The amount receivable from or (due to) related parties comprised the following:

<TABLE>
<CAPTION>
                                            December 31,
(in thousands)                                 1997
- ------------------------------------------------------------
<S>                                           <C>
Receivable from NYLCare                       $ 23,709
Due to NYLCare                                  (7,479)
                                            ================
Total related party receivable                $ 16,230
                                            ================
</TABLE>

     Prior to July 15, 1998, the Company was the exclusive  provider of pharmacy
benefit  management  services to  NYLCare's  managed  health care  subsidiaries,
subject to certain  exceptions.  The Company's  agreement with NYLCare  provided
that fees from  drug  manufacturers  whose  products  are used in the  Company's
formularies related to NYLCare subsidiaries was allocated 100% to the Company up
to $400,000  and 75% to NYLCare and 25% to the Company  thereafter.  The Company
was also the non-exclusive  provider of pharmacy benefit management  services to
New York Life and Health Insurance Company ("NYLHIC"),  a subsidiary of NYLCare.
In 1996  fees  from  drug  manufacturers  with  respect  to this  business  were
allocated  100% to the Company.  Effective  January 1, 1997,  the Company shared
such fees with NYLHIC on a fixed per script amount which approximates 40% of the
total of such fees.

     Such fees allocated to NYLCare and NYLHIC were $7,257,000,  $11,690,000 and
$7,636,000  in 1998,  1997  and  1996,  respectively,  and  $2,307,000  in 1998,
$5,803,000 in 1997 and $3,064,000 in 1996 were allocated to the Company and have
been classified in the  accompanying  consolidated  statement of operations as a
reduction of cost of revenues.

     As discussed  in Note 3, the Company has entered into a ten year  corporate
alliance with Premier. Richard Norling is the Chief Operating Officer of Premier
and a member of the Company's Board of Directors. No consideration,  monetary or
otherwise, has been exchanged between the Company and Premier between the period
September  1997 and  December  1998 (the  period  during  which  Premier and the
Company are related  parties).  The Company may be required to issue  additional
shares of its Class A Common Stock to Premier as discussed in Note 3.

     Premier is required to promote the Company as the preferred PBM provider to
health care  entities,  plans and  facilities  which  participate  in  Premier's
purchasing programs.  However, all contractual  arrangements to provide services
are made directly  between the Company and these entities,  at varying terms and
independent  of any Premier  involvement.  Therefore,  the  associated  revenues
earned and expenses  incurred by the Company are not deemed to be related  party
transactions.  During  1998,  the net  revenues  that the Company  derived  from
services  provided  to the  health  care  entities  participating  in  Premier's
purchasing programs was $78,539,000.

5.       Property and equipment

Property and equipment, at cost, consists of the following:
<TABLE>
<CAPTION>

                                                           December 31,
(in thousands)                                     1998                    1997
- --------------------------------------------------------------------------------
<S>                                             <C>                       <C>
Land                                            $  2,051                  $    -
Building                                           3,076
Furniture                                          8,336                   4,362
Equipment                                         52,758                  28,924
Computer software                                 37,412                  12,011
Leasehold improvements                             8,275                   3,934
                                          --------------------------------------
                                                 111,908                  49,231
Less accumulated depreciation and
    amortization                                  34,409                  22,410
                                           -------------------------------------
                                                $ 77,499                $ 26,821
                                          ======================================
</TABLE>

6.       Financing

     On April 1, 1998, the Company  executed a $440 million credit facility with
a bank syndicate led by Bankers Trust Company, consisting of a $360 million term
loan facility and an $80 million  revolving loan facility.  The credit  facility
expires  on  April  15,  2003  and  is  guaranteed  by  the  Company's  domestic
subsidiaries  other than Practice  Patterns  Science,  Inc.  ("PPS"),  and Great
Plains Reinsurance  Company ("Great Plains") and secured by pledges of 100% (or,
in the case of foreign subsidiaries,  65%) of the capital stock of the Company's
subsidiaries  other  than PPS and  Great  Plains.  The  provisions  of this loan
require quarterly  interest payments and,  beginning in April 1999,  semi-annual
principal  payments.  The  interest  rate is  based on a  spread  ("Credit  Rate
Spread") over several  London  Interbank  Offered  Rates  ("LIBOR") or base rate
options,  depending upon the Company's ratio of earnings before interest, taxes,
depreciation and amortization to debt ("Leverage  Ratio"). At December 31, 1998,
the interest rate was 6.0625%,  representing  a credit rate spread of 0.75% over
the three month LIBOR rate. The credit  facility  contains  covenants that limit
the  indebtedness  the  Company  may  incur and the  amount  of  annual  capital
expenditures.  The covenants also establish a minimum interest coverage ratio, a
maximum  leverage ratio,  and a minimum  consolidated net worth. At December 31,
1998, the Company was in compliance with all covenants. In addition, the Company
is required to pay an annual fee  depending  on the leverage  ratio,  payable in
quarterly  installments,  on the  unused  portion  of the  revolving  loan.  The
commitment  fee was 22.5  basis  points at  December  31,  1998.  There  were no
borrowings at December 31, 1998 under the revolving loan facility.  The carrying
amount of the Company's term loan facility approximates fair value.

In conjunction  with the credit facility and as part of the Company's  policy to
manage  interest  rate risk,  the Company  entered  into an  interest  rate swap
agreement ("swap") with The First National Bank of Chicago, a subsidiary of Bank
One Corporation, on April 3, 1998. At December 31, 1998, the swap had a notional
principal  amount of $360  million.  Under the  terms of the swap,  the  Company
agrees to receive a  floating  rate of  interest  on the amount of the term loan
facility  based on a three month  LIBOR rate in exchange  for payment of a fixed
rate of interest of 5.88% per annum.  The notional  principal amount of the swap
amortizes in equal amounts with the principal balance of the term loan facility.
As a result,  the Company has, in effect,  converted its variable rate term debt
to fixed  rate  debt at 5.88% per  annum  for the  entire  term of the term loan
facility, plus the Credit Rate Spread.

     The following  represents  the schedule of current  maturities for the term
loan facility (amounts in thousands):

<TABLE>
<CAPTION>

  Year Ended December 31,
- ------------------------------------------
<S>      <C>                  <C>
         1999                 $    54,000
         2000                      72,000
         2001                      90,000
         2002                      96,000
         2003                      48,000
                             =============
                              $   360,000
                             =============
</TABLE>

     Prior to April 1, 1998, the Company maintained a $25,000,000 unsecured line
of credit with the  Mercantile  Bank National  Association  which was terminated
upon the consummation of the Bankers' Trust credit facility.  Additionally,  the
Company  allowed another line of credit in the amount of $25 million to lapse on
October 31, 1997. Terms of the agreements were as follows:  interest was charged
on the  principal  amount  outstanding  at a rate equal to any of the  following
options  which the Company,  at its option shall  select:  (i) the bank's "prime
rate", (ii) a floating rate equal to the Bank's cost of funds rate plus 50 basis
points, or (iii) a fixed rate for periods of 30, 60, 90 or 180 days equal to the
LIBOR rate plus 50 basis points. Fees under the agreements on any unused portion
were charged at ten  hundredths  of one percent per year.  At December 31, 1997,
the Company  had no  outstanding  borrowings  under this  agreement,  nor did it
borrow any amounts under these agreements during 1997.


7.       Corporate restructuring

     During  1998,  the  Company  recorded  a  pre-tax  restructuring  charge of
$1,651,000  ($1,002,000  after taxes or $0.03 per basic  earnings  per share and
$0.03 per dilutive  earnings per share)  associated with the Company closing the
non-PBM service  operations of its wholly-owned  subsidiary,  PhyNet,  Inc., and
transferring  certain  functions of its Express  Scripts  Vision  Corporation to
another vision care provider.

<TABLE>
<CAPTION>
                                                                                                   Balance at
                                                         1998                     Utilized        December 31,
(amounts in thousands)                         Charge             Cash            Noncash            1998
<S>                                                 <C>                 <C>              <C>               <C>
- ---------------------------------------------------------------------------------------------------------------
Write-down of long-lived assets                     $1,235              $  -             $704              $531
Employee transition costs for 61 employees             416               184                -               232
                                              =================================================================
                                                    $1,651              $184             $704              $763
                                              =================================================================
</TABLE>


The  restructuring  charge  includes  tangible  assets to be  disposed  of being
written down to their net realizable  value,  less cost of disposal.  Management
expects  recovery to approximate its cost of disposal.  Considerable  management
judgment is necessary to estimate fair value, accordingly,  actual results could
vary from such estimates.  The Company  anticipates  completing the remainder of
the restructuring actions by the end of the third quarter of 1999.


8.       Income taxes

         The income tax provision consists of the following:
<TABLE>
<CAPTION>

                                                                                 Year Ended December 31,
(in thousands)                                                     1998                    1997                    1996
<S>                                                              <C>                     <C>                     <C>
- -------------------------------------------------------------------------------------------------------------------------
Current provision:
    Federal                                                      $ 20,171                $ 19,048                $ 13,945
    State                                                           3,049                   2,779                   2,480
    Foreign                                                           278                     284                     190
                                                   ----------------------------------------------------------------------
        Total current provision                                    23,498                  22,111                  16,615
                                                   ----------------------------------------------------------------------
Deferred provision:
    Federal                                                         8,694                   (714)                     267
    State                                                           1,374                   (120)                      50
                                                   ----------------------------------------------------------------------
        Total deferred provision                                   10,068                   (834)                     317
                                                   ======================================================================
Total current and deferred provision                             $ 33,566                $ 21,277                $ 16,932
                                                   ======================================================================
</TABLE>

     A reconciliation of the statutory federal income tax rate and the effective
tax rate  follows  (The effect of foreign  taxes on the  effective  tax rate for
1998, 1997 and 1996 is immaterial):


<TABLE>
<CAPTION>
                                                                          Year Ended December 31,
                                                            1998                    1997                    1996
- ---------------------------------------------------------------------------------------------------------------------
<S>                                                        <C>                     <C>                     <C>
Statutory federal income tax rate                          35.0%                   35.0%                   35.0%
State taxes net of federal benefit                          3.8                     3.8                     4.3
Non-deductible amortization of goodwill and
    Customer contracts                                      4.9
Other, net                                                  0.3                     0.1                      -
                                                   ==================================================================
Effective tax rate                                         44.0%                   38.9%                   39.3%
                                                   ==================================================================

</TABLE>


     The  deferred  tax assets and  deferred  tax  liabilities  recorded  in the
consolidated balance sheet are as follows:

<TABLE>
<CAPTION>

                                                                            December 31,
(in thousands)                                                     1998                    1997
<S>                                                                <C>                     <C>
- -------------------------------------------------------------------------------------------------
Deferred tax assets:
   Allowance for bad debts                                         $8,013                  $1,578
   Inventory costing capitalization and reserves                      684                     675
   Accrued expenses                                                34,170                     512
   Depreciation and property differences                            6,808
   Non-compete agreements                                             933
   Other                                                               17                      79
                                                   ----------------------------------------------
       Gross deferred tax assets                                   50,625                   2,844
Deferred tax liabilities:
   Depreciation and property differences                                                  (1,166)
   Other                                                            (462)                    (91)
                                                   ----------------------------------------------
       Gross deferred tax liabilities                               (462)                 (1,257)
                                                   ----------------------------------------------

Net deferred tax assets                                          $ 50,163                  $1,587
                                                   ==============================================
</TABLE>

     The  Company  believes  it is probable  that the net  deferred  tax assets,
reflected  above,  will be  realized in future tax  returns  primarily  from the
generation of future taxable income.

9.       Commitments and contingencies

     The Company has entered into  noncancellable  agreements  to lease  certain
office  and  distribution  facilities  with  remaining  terms from one to eleven
years.  Rental expense under the office and  distribution  facilities  leases in
1998, 1997 and 1996 was $3,876,000, $2,272,000 and $2,099,000, respectively. The
future minimum lease payments due under  noncancellable  operating  leases is as
follows:

<TABLE>
<CAPTION>


 Year Ended December 31,
- --------------------------------------------------------
<S>       <C>                     <C>
          1999                    $  5,555,000
          2000                       5,960,000
          2001                       5,873,000
          2002                       5,758,000
          2003                       5,667,000
       Thereafter                   28,648,000
                                 =======================
                                  $ 57,462,000
                                 =======================
</TABLE>

     For the year ended December 31, 1998,  approximately 56.2% of the Company's
pharmaceutical purchases were through one wholesaler. The Company believes other
alternative  sources are readily available and that no other concentration risks
exist at December 31, 1998.

     In the ordinary course of business  (which includes the business  conducted
by ValueRx prior to the Company's  acquisition on April 1, 1998),  various legal
proceedings,  investigations  or claims  pending have arisen against the Company
and its  subsidiaries  (ValueRx  continues to be a party to several  proceedings
that  arose  prior to April 1,  1998).  The  effect of these  actions  on future
financial results is not subject to reasonable  estimation because  considerable
uncertainty  exists  about  the  outcomes.   Nevertheless,  in  the  opinion  of
management,   the  ultimate  liabilities   resulting  from  any  such  lawsuits,
investigations or claims now pending will not materially affect the consolidated
financial position, results of operations, or cash flows of the Company.

10.  Employee benefit plans

     Retirement savings plan. The Company offers all of its full-time  employees
a retirement  savings plan under  Section  401(k) of the Internal  Revenue Code.
Employees may elect to enter a written salary  deferral  agreement under which a
maximum of 10% of their salary  (effective  January 1, 1999 maximum  deferral is
12%),  subject to aggregate limits required under the Internal Revenue Code, may
be  contributed  to the  plan.  The  Company  matches  the  first  $2,000 of the
employee's contribution for the year. For the year ended December 1998, 1997 and
1996, the Company made contributions of approximately  $1,751,000,  $909,000 and
$639,000, respectively.

     Employee stock  purchase  plan. In December  1998,  the Company's  Board of
Directors  approved an employee stock purchase  plan,  effective  March 1, 1999,
that  qualifies  under Section 423 of the Internal  Revenue Code and permits all
employees,  excluding certain management level employees,  to purchase shares of
the  Company's  Class A  Common  Stock.  Participating  employees  may  elect to
contribute up to 10% of their salary to purchase common stock at the end of each
six month  participation  period at a  purchase  price  equal to 85% of the fair
market value of the common stock at the end of the participation period. Class A
Common Stock reserved for future  employee  purchases under the plan was 250,000
at December 31, 1998.


     Deferred compensation plan. In December,  1998, the Compensation  Committee
of the Board of Directors  approved a non-qualified  deferred  compensation plan
(the "Executive Deferred  Compensation  Plan"),  effective January 1, 1999, that
provides  benefits payable to eligible key employees at retirement,  termination
or death.  Benefit  payments are funded by a combination of  contributions  from
participants  and the  Company.  Participants  become  fully  vested in  Company
contributions on the third anniversary of the end of the plan year for which the
contribution  is  credited  to their  account.  For  1999,  the  annual  Company
contribution   will  be  equal  to  6%  of  each   participant's   total  annual
compensation,  with 25% being invested in the Company's Class A Common Stock and
the remaining being allocated to a variety of investment  options.  As a result,
of the implementation,  the Company accrued as compensation  expense $797,000 in
1998 as a past service  contribution  which is equal to 8% of each participant's
total annual cash compensation for the period of the participant's  past service
with the Company in a senior executive capacity.


11.      Common stock

     The  holders  of Class A Common  Stock  have  one vote per  share,  and the
holders of Class B Common  Stock  have ten votes per  share.  NYLIFE is the sole
holder of Class B Common  Stock.  Class B Common  Stock  converts  into  Class A
Common Stock on a  share-for-share  basis upon transfer  (other than to New York
Life or its  affiliates) and is convertible at any time at the discretion of the
holder.  At December  31,  1998,  NYLIFE and the holders of Class A Common Stock
have control over approximately 89.0% and 11.0%,  respectively,  of the combined
voting power of all classes of Common Stock.

     In April 1996, NYLIFE converted 5,980,000 shares of Class B Common Stock to
Class A Common  Stock  and sold the  Class A shares  in a public  offering.  The
Company did not receive any proceeds from the sale of these shares.  The Company
sold an  additional  2,300,000  Class A shares in the same  stock  offering  and
received  net  proceeds of  $52,592,000  after  deducting  expenses  incurred in
connection with the offering.


     In October 1998,  the Company  announced a  two-for-one  stock split of its
Class A and Class B Common Stock for stockholders of record on October 20, 1998,
effective  October 30, 1998. The split was effected in the form of a dividend by
issuance of one additional share of Class A Common Stock for each share of Class
A Common Stock  outstanding and one additional share of Class B Common Stock for
each share of Class B Common Stock  outstanding.  The earnings per share and the
weighted average number of shares outstanding for basic and diluted earnings per
share have been adjusted for the stock split except on the Consolidated  Balance
Sheet and the Consolidated Statement of Changes in Stockholder's Equity.


     As of December 31,  1998,  the Company had  repurchased  a total of 475,000
shares  of its  Class A Common  Stock  under the  open-market  stock  repurchase
program  announced by the Company on October 25, 1996,  although no  repurchases
occurred during 1998. The Company's  Board of Directors  approved the repurchase
of up to 1,700,000  shares,  and placed no limit on the duration of the program.
Future  purchases,  if any,  will be in such  amounts  and at such  times as the
Company deems appropriate based upon prevailing market and business  conditions,
subject to certain restrictions in the credit agreement described above.

     As of December 31, 1998,  5,807,000  shares of the Company's Class A Common
Stock have been  reserved for issuance to  organizations  with which the Company
has signed contractual agreements (see Note 3).

12.      Stock-based compensation plans

     At December 31, 1998, the Company has three fixed stock-based  compensation
plans, which are described below.

     In April 1992, the Company  adopted a stock option plan which it amended in
1995,  which provides for the grant of nonqualified  stock options and incentive
stock  options to officers  and key  employees  of the  Company  selected by the
Compensation  Committee  of the Board of  Directors.  Initially,  a  maximum  of
1,400,000  shares of Class A Common Stock could be issued  under the plan.  That
amount increases  annually each January 1, from January 1, 1993 to and including
January 1, 1999 by  140,000,  to a maximum of  2,380,000  shares.  By  unanimous
written  consent dated June 6, 1994, the Board of Directors  adopted the Express
Scripts,  Inc.  1994 Stock Option Plan,  also amended in 1995,  1997 and 1998. A
total  of  1,920,000  shares  of the  Company's  Class A Common  Stock  has been
reserved for issuance under this plan.  Under either plan, the exercise price of
the options may not be less than the fair market value of the shares at the time
of grant.  The  Compensation  Committee has the  authority to establish  vesting
terms, and typically provides that the options vest over a five-year period from
the date of grant. The options may be exercised,  subject to a ten-year maximum,
over a period determined by the Committee.

     In April  1992,  the  Company  also  adopted a stock  option plan which was
amended  in 1995 and 1996  and  provides  for the  grant of  nonqualified  stock
options to purchase 48,000 shares to each director who is not an employee of the
Company or its  affiliates.  A maximum of 384,000 shares of Class A Common Stock
may be issued  under this plan at a price equal to fair market value at the date
of grant.  The plan  provides  that the options  vest over a three- or five-year
period from the date of grant.

     The Company  applies APB 25 and related  interpretations  in accounting for
its plans.  Accordingly,  no compensation cost has been recognized for its stock
options plans. Had compensation cost for the Company's stock based  compensation
plans  been  determined  based on the fair  value at the grant  dates for awards
under  those  plans  consistent  with the  method  prescribed  by FAS  123,  the
Company's  net income and  earnings per share would have been reduced to the pro
forma amounts  indicated below. Note that due to the adoption of the methodology
prescribed by FAS 123, the pro forma results shown below only reflect the impact
of options granted in 1998, 1997 and 1996. Because future options may be granted
and vesting typically occurs over a five year period, the pro forma impact shown
for  1998,  1997 and 1996 is not  necessarily  representative  of the  impact in
future years.
<TABLE>
<CAPTION>


(IN THOUSANDS, EXCEPT PER SHARE DATA)           1998            1997            1996
<S>                                           <C>             <C>             <C>
- -------------------------------------------------------------------------------------
Net income
    As reported                               $42,674         $33,429         $26,148
    Pro forma                                  38,585          32,034          25,235

Basic earnings per share
    As reported                             $    1.29       $    1.02       $    0.81
    Pro forma                                    1.16            0.98            0.78

Diluted earnings per share
    As reported                             $    1.27       $    1.01       $    0.80
    Pro forma                                    1.14            0.97            0.77

</TABLE>

     The fair value of options  granted  (which is amortized to expense over the
option vesting period in determining the pro forma impact),  is estimated on the
date of grant using the  Black-Scholes  multiple  option-pricing  model with the
following weighted average assumptions:

<TABLE>
<CAPTION>

                                 1998              1997          1996
<S>                             <C>            <C>           <C>
- -------------------------------------------------------------------------
Expected life of option         2-7 years      2-7 years     1-6 years
Risk-free interest rate          4.1-5.9%       5.7-6.6%     5.0-6.5%
Expected volatility of stock       44%            40%         30-50%
Expected dividend yield            None           None         None

</TABLE>

     A summary of the status of the Company's  three fixed stock option plans as
of December  31,  1998,  1997 and 1996,  and changes  during the years ending on
those dates is presented below.

<TABLE>
<CAPTION>

                                                1998                      1997                           1996
                                     ---------------------------------------------------------------------------------------
                                                   Weighted-Average            Weighted-Average             Weighted-Average
                                                     Exercise                    Exercise                    Exercise
                                                      Price                        Price                       Price
(share data in thousands)                 Shares                      Shares                       Shares
<S>                                         <C>       <C>               <C>        <C>               <C>      <C>
- ----------------------------------------------------------------------------------------------------------------------------
Outstanding at beginning of year            1,702     $17.21            1,677      $12.56            1,446    $ 10.30
Granted                                     1,866     40.65               602      22.78               642     19.85
Exercised                                   (133)     14.71             (529)       8.80             (131)         9.98
Forfeited/cancelled                         (655)     38.82              (48)      17.56             (280)     18.80
                                     =============               =============                =============
Outstanding at end of year                  2,780     28.02             1,702      17.21             1,677     12.56
                                     =============               =============                =============
Options exercisable at year end               800                         641                          756



Weighted-average fair value of
  options granted during the year          $18.07                      $ 9.91                       $ 6.57


</TABLE>

     The  following  table  summarizes  information  about fixed  stock  options
outstanding at December 31, 1998:

<TABLE>
<CAPTION>

                                         Options Outstanding                                 Options Exercisable
                     -----------------------------------------------------------    -----------------------------------
     Range of
  Exercise Prices          Number         Weighted-Average                                Number       Weighted-Average
  (SHARE DATA IN       Outstanding at        Remaining         Weighted-Average         Exercisable     Exercise Price
    THOUSANDS)            12/31/98        Contractual Life      Exercise Price          at 12/31/98
<S>           <C>                   <C>                 <C>                <C>                     <C>           <C>
- -------------------- -----------------------------------------------------------    -----------------------------------
   $   3.25 - 15.25                 561                 5.33               $10.09                  426           $ 8.71
      15.50 - 23.50                 618                 7.15                18.64                  278            18.47
      24.50 - 35.63               1,013                 8.99                31.22                   96            26.02
      37.44 - 42.39                 218                 9.44                39.89
              55.13                 370                 9.96                55.13                    -
                     ===================                                              =================
   $   3.25 - 55.13               2,780                 8.01                28.02                  800            14.17
                     ===================                                              =================

</TABLE>

13.      Segment information

     The  Company  is  organized  on the  basis  of  services  offered  and  has
determined  that  it has two  reportable  segments:  PBM  services  and  non-PBM
services (defined in Note 1 "organization and operations").  The Company manages
the  pharmacy   benefit  within  an  operating   segment  which   encompasses  a
fully-integrated PBM service. The remaining three operating service lines (IVTx,
Specialty Distribution and Vision) have been aggregated into a non-PBM reporting
segment.

The following table presents  information about the reportable  segments for the
years ended December 31:

<TABLE>
<CAPTION>

 (IN THOUSANDS)                                                   PBM                   NON-PBM               TOTAL
<S>                                                        <C>                     <C>                    <C>
- -----------------------------------------------------------------------------------------------------------------------
 1998
Net revenues                                               $   2,765,111           $      59,761          $   2,824,872
Depreciation and amortization expense (1)                         25,540                     983                 26,433
Interest income                                                    7,235                       1                  7,236
Interest expense (1)                                              20,218                      12                 20,230
Income before income taxes                                        70,107                   6,133                 76,240
Total assets                                                   1,068,715                  26,746              1,095,461
Capital expenditures                                              23,432                     421                 23,853
- -----------------------------------------------------------------------------------------------------------------------
 1997
Net revenues                                               $   1,191,173           $      39,461          $   1,230,634
Depreciation and amortization expense                              9,704                     766                 10,470
Interest income                                                    6,080                       1                  6,081
Interest expense                                                     209                      16                    225
Income before income taxes                                        52,529                   2,177                 54,706
Total assets                                                     385,330                  17,178                402,508
Capital expenditures                                              10,782                   2,235                 13,017
- -----------------------------------------------------------------------------------------------------------------------
 1996
Net revenues                                              $      743,077           $      30,538         $      773,615
Depreciation and amortization expense                              6,273                     434                  6,707
Interest income                                                    3,509                                          3,509
Interest expense                                                      51                       8                     59
Income before income taxes                                        39,938                   3,142                 43,080
Total assets                                                     286,433                  13,992                300,425
Capital expenditures                                               8,306                   1,174                  9,480
- -----------------------------------------------------------------------------------------------------------------------
<FN>

     (1) The amortization  expense for deferred financing fees ($609 in 1998) is
included in interest expense on the Consolidated  Statement of Operations and in
depreciation and amortization on the Consolidated Statement of Cash Flows.
</FN>
</TABLE>

14.   Quarterly financial data (unaudited)

     The following table  summarizes the quarterly  financial data for the years
ended December 31, 1998 and 1997:

<TABLE>
<CAPTION>

                                                                                                   Earnings Per Share
                                                            Selling,                              ---------------------
(in thousands, except per        Net         Cost of       General &       Operating   Net
    share data                Revenues     Revenues     Administrative     Income      Income      Basic     Diluted
<S>                             <C>          <C>                <C>          <C>         <C>         <C>       <C>
- -----------------------------------------------------------------------------------------------------------------------
 1998
March 31, 1998                   $371,362     $338,492           $18,826      $14,044     $9,878      $0.30     $0.29
June 30, 1998                     807,406      743,557            39,266       22,932      9,568       0.29      0.28
September 30, 1998                807,319      738,544            43,153       25,622     11,303       0.34      0.34
December 31, 1998                 838,784      764,403            47,745       26,636     11,924       0.36      0.35
- -----------------------------------------------------------------------------------------------------------------------
 1997
March 31, 1997                   $261,990     $237,298           $13,298      $11,394     $7,641      $0.23     $0.23
June 30, 1997                     300,515      274,906            13,733       11,876      8,131       0.25      0.25
September 30, 1997                319,937      291,590            15,758       12,589      8,613       0.26      0.26
December 31, 1997                 348,192      315,373            19,828       12,991      9,044       0.27      0.27

</TABLE>

15.      Subsequent event - potential acquisition


     On  February  9,  1999,  the  Company  announced  that  it had  executed  a
definitive  agreement  to purchase  Diversified  Pharmaceutical  Services,  Inc.
("DPS"), a wholly-owned subsidiary of SmithKline Beecham Corporation.  Under the
terms of the agreement,  the Company will pay cash in the amount of $700 million
for the stock of DPS.  The  Company  expects to finance the  purchase  through a
$1.05  billion bank credit  facility  consisting of a $750 million term facility
and a $300 million  revolving  credit  facility.  In  addition,  the Company has
secured  bridge  financing in the amount of $150 million to facilitate  closing.
The loan  proceeds  will be used  towards the $700  million  purchase  price and
acquisition  related  costs,  and will also be used to refinance  the  Company's
existing $440 million bank credit  facility (see Note 6) and provide for working
capital  needs,  if any.  The Company  expects to issue $350  million in Class A
Common Stock through an offering. Net proceeds from the offering will be used to
retire the $150 million  bridge  facility and a portion of the $750 million term
facility.  The  acquisition  will be accounted for under the purchase  method of
accounting and is subject to customary  closing  conditions  including  required
governmental approvals and consummation and funding of the bank credit facility.
The Company  anticipates  the  transaction  will close in the second  quarter of
1999.

     Should the  transaction  close and the Company  refinance its existing $440
million bank credit facility,  the remaining unamortized deferred financing fees
will be expensed as an extraordinary item. The Company  anticipates  maintaining
its existing  interest rate swap in place to hedge the future variable  interest
rate  payments  on $360  million  of the  proposed  $1.05  billion  bank  credit
facility.


     The  following  unaudited  pro forma  information  presents  a  summary  of
combined results of operations of the Company,  the Acquired Entities and DPS as
if the acquisitions and relative  financings,  including the equity offering had
occurred at the beginning of the period presented,  along with certain pro forma
adjustments to give effect to amortization of goodwill, other intangible assets,
interest  expense  on  acquisition  debt and  other  adjustments.  The pro forma
financial information is not necessarily indicative of the results of operations
as they would have been had the transaction  been effected on the assumed dates.
Included in the pro forma  information  are  integration  costs  incurred by the
Company  for the  Acquired  Entities  that are being  reported  within  selling,
general and administrative expenses in the statement of operations.


<TABLE>
<CAPTION>

                                                  Year Ended December 31,
(in thousands, except per share data)                       1998
- -------------------------------------------------------------------------------
<S>                                                     <C>
Net revenues                                            $3,449,649
Net income                                                  51,130
Basic earnings per share                                      1.36
Diluted earnings per share                                    1.34

</TABLE>

Item 9 - Changes in and Disagreements with Accountants on Accounting and
Financial Disclosure

         None.

                                    PART III


Item 10 - Directors and Executive Officers of the Registrant

     The  information  required by this item will be  incorporated  by reference
from the Company's  definitive  Proxy  Statement for its 1999 Annual  Meeting of
Stockholders  to be filed  pursuant to  Regulation  14A (the "Proxy  Statement")
under the heading "I.  Election of  Directors";  provided that the  Compensation
Committee Report on Executive  Compensation and the performance  graph contained
in the  Proxy  Statement  shall not be deemed  to be  incorporated  herein;  and
further provided that the information regarding the Company's executive officers
required  by Item  401 of  Regulation  S-K has been  included  in Part I of this
report.


Item 11 - Executive Compensation

     The  information  required by this item will be  incorporated  by reference
from  the  Proxy  Statement  under  the  headings   "Directors'   Compensation,"
"Compensation  Committee  Interlocks and Insider  Participation"  and "Executive
Compensation."


Item 12 - Security Ownership of Certain Beneficial Owners and Management

     The  information  required by this item will be  incorporated  by reference
from the Proxy  Statement  under the  headings  "Security  Ownership  of Certain
Beneficial Owners and Management."


Item 13 - Certain Relationships and Related Transactions

     The  information  required by this item will be  incorporated  by reference
from the Proxy Statement under the heading  "Certain  Relationships  and Related
Transactions."

                                     PART IV

Item 14 - Exhibits, Financial Statement Schedules and Reports on Form 8-K

(a)  Documents filed as part of this Report

     (1) Financial Statements

         The following  report of independent  accountants and the  consolidated
financial  statements  of the Company are  contained  in this Report on the page
indicated

                                                               Page No. In
                                                                Form 10-K


          Report of Independent Accountants                       42

          Consolidated Balance Sheet as of
              December 31, 1998 and 1997                          43

          Consolidated Statement of Operations
              for the years ended December 31, 1998,
              1997 and 1996                                       44

          Consolidated Statement of Changes in
              Stockholders' Equity for the years ended
              December 31, 1998 and 1997                          45

          Consolidated Statement of Cash Flows for
              the years ended December 31, 1998,
              1997 and 1996                                       46

          Notes to Consolidated Financial Statements              47


      (2) The following financial statement schedule is contained in
this Report on the page indicated.
                                                              Page No. In
Financial Statement Schedule:                                  Form 10-K


      VIII.  Valuation and Qualifying Accounts
             and Reserves for the years ended
             December 31, 1998, 1997 and 1996                     69


        All other  schedules are omitted  because they are not applicable or the
required  information is shown in the consolidated  financial  statements or the
notes thereto.

      (3)  List of Exhibits


          See Index to Exhibits on pages 70 - 76.


(b)  Reports on Form 8-K


        (i)      On October 27,  1998,  the  Company  filed a
                 Current  Report on Form 8-K,  dated  October
                 12,  1998 under  Items 5 and 7,  regarding a
                 press  release   issued  on  behalf  of  the
                 Company  announcing a 2-for-1 stock split of
                 its common stock, to be effected in the form
                 of a 100% stock dividend.

        (ii)     On October 29,  1998,  the  Company  filed a
                 Current  Report on Form 8-K,  dated  October
                 21,  1998 under  Items 5 and 7,  regarding a
                 press  release   issued  on  behalf  of  the
                 Company  concerning  its third  quarter 1998
                 financial performance.

        (iii)    On November  20, 1998,  the Company  filed a
                 Current  Report on Form 8-K,  dated November
                 1, 1998  under  Items 5 and 7,  regarding  a
                 press  release   issued  on  behalf  of  the
                 Company announcing that the 2-for-1 split of
                 its common stock had been effected.



                                   SIGNATURES

     Pursuant  to the  requirements  of  Section  13 or 15(d) of the  Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on
its behalf by the undersigned thereunto duly authorized.

                                        EXPRESS SCRIPTS, INC.



June 10, 1999                            By: *
                                              Barrett A. Toan, President
                                               and Chief Executive Officer



      Pursuant to the requirements of the Securities  Exchange Act of 1934, this
report  has  been  signed  below  by the  following  persons  on  behalf  of the
registrant and in the capacities and on the dates indicated.

Signature                   Title                               Date



     *                      President,                          June 10, 1999
Barrett A. Toan             Chief Executive
                            Officer and Director

     *                      Senior Vice President and           June 10, 1999
George Paz                  Chief Financial Officer


     *                      Vice President and                  June 10, 1999
Joseph W. Plum              Chief Accounting
                            Officer

     *                      Director                            June 10, 1999
Howard I. Atkins


     *                      Director                            June 10, 1999
Judith E. Campbell

     *                      Director                            June 10, 1999
Richard M. Kernan, Jr.


     *                      Director                            June 10, 1999
Richard A. Norling


     *                      Director                            June 10, 1999
Frederick J. Sievert


     *                      Director                            June 10, 1999
Stephen N. Steinig


     *                      Director                            June 10, 1999
Seymour Sternberg


     *                      Director                            June 10, 1999
Howard L. Waltman


     *                      Director                            June 10, 1999
Norman Zachary

 *By: /s/ Keith J. Ebling
      As attorney-in-fact for the
      person indicated



<PAGE>


                              EXPRESS SCRIPTS, INC.
         Schedule VIII - Valuation and Qualifying Accounts and Reserves
                  Years Ended December 31, 1996, 1997 and 1998


<TABLE>
<CAPTION>


COL. A                 COL. B                 COL. C                COL.D        COL. E
                                            Additions
                    Balance             Charges    Charges                       Balance
                         at             to Costs   to Other                      at End
                    Beginning             and         and                          of
Description         Of period           Expenses   Accounts      (Deductions)    Period
<S>        <C>      <C>              <C>                        <C>             <C>
- ---------------------------------------------------------------------------------------------
Allowance for
Doubtful Accounts
Receivable

Year Ended 12/31/96  $2,273,937       $1,456,130                 $  1,394,922    $  2,335,145
Year Ended 12/31/97  $2,335,145       $3,680,409                 $  1,213,991    $  4,801,563
Year Ended 12/31/98  $4,801,563       $4,583,008  $9,570,069(1)  $  1,148,356    $ 17,806,284

<FN>
     1 Represents  the opening  balance  sheet for the  Company's  April 1, 1998
acquisition of ValueRx.
</FN>
</TABLE>


<PAGE>

                                INDEX TO EXHIBITS
            (Express Scripts, Inc. - Commission File Number 0-20199)

Exhibit
Number         Exhibit

2.1            Stock Purchase Agreement by and among Columbia/HCA Healthcare
               Corporation, VH Holdings, Inc., Galen Holdings, Inc. and Express
               Scripts, Inc., dated as of February 19, 1998, and certain related
               Schedules, incorporated by reference to Exhibit No. 2.1 to the
               Company's Current Report on Form 8-K filed March 2, 1998.

2.2            First Amendment to Stock Purchase Agreement by and among
               Columbia/HCA Healthcare Corporation, VH Holdings, Inc., Galen
               Holdings, Inc. and Express Scripts, Inc., dated as of
               March 31, 1998, and related Exhibits incorporated by reference
               to Exhibit No. 2.1 to the Company's Current Report on Form 8-K
               filed April 14, 1998.

2.3            Stock Purchase Agreement by and among SmithKline Beecham
               Corporation, SmithKline Beecham InterCredit BV and Express
               Scripts, Inc., dated as of February 9, 1999, and certain related
               Schedules, incorporated by reference to Exhibit No. 2.1 to the
               Company's Current Report on Form 8-K filed February 18, 1999.

3.1            Certificate of Incorporation, incorporated by reference to
               Exhibit No. 3.1 to the Company's Registration Statement on
               Form S-1 filed June 9, 1992 (No. 33-46974) (the "Registration
               Statement").

3.2            Certificate of Amendment of the Certificate of Incorporation of
               the Company, incorporated by reference to Exhibit No.10.6 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               June 30, 1994.

3.3*           Certificate of Amendment of the Certificate of Incorporation of
               the Company.

3.4            Second Amended and Restated Bylaws, incorporated by reference to
               Exhibit No. 3.3 to the Company's Quarterly Report on Form 10-Q
               for the quarter ending September 30, 1997.

4.1            Form of Certificate for Class A Common Stock, incorporated by
               reference to Exhibit No. 4.1 to the Registration Statement.

10.1**         Stock Agreement (Initial Shares) entered into as of December 31,
               1995, between the Company and American Healthcare Purchasing
               Partners, L.P., incorporated by reference to Exhibit No. 10.61 to
               the Company's Annual Report on Form 10-K for the year ending
               1995.

10.2**         Stock Agreement (Membership Shares) entered into as of December
               31, 1995, between the Company and American Healthcare Purchasing
               Partners, L.P., incorporated by reference to Exhibit No. 10.62 to
               the Company's Annual Report on Form 10-K for the year ending
               1995.

10.3**         Amended and Restated Agreement entered into as of March 29, 1995,
               between the Company and Sanus Corp. Health Systems, incorporated
               by reference to Exhibit No. 10.1 to the Company's Annual Report
               on Form 10-K for the year ending 1995.

10.4**         Form of Amended and Restated Managed Prescription Drug Program
               Agreement entered into as of March 29, 1995, between the Company
               and each of the following parties: Health Plus, Inc., Sanus
               Health Plan of New Jersey, Inc., Sanus Texas Health Plan, Inc.,
               Sanus/New York Life Health Plan, Inc., Sanus Health Plan of
               Illinois, Inc. and Sanus Health Plan of Greater New York, Inc.,
               incorporated by reference to Exhibit No. 10.2 to the Company's
               Annual Report on Form 10-K for the year ending 1995.

10.5**         Managed Prescription Drug Program Agreement dated as of May 1,
               1996 by and between the Company and NYLCare Health Plans of
               Maine, Inc., incorporated by reference to Exhibit No. 10.3 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               March 31, 1997.

10.6**         Managed Prescription Drug Program Agreement dated as of December
               31, 1995 by and between the Company and WellPath Community Health
               Plan, Inc., incorporated by reference to Exhibit No. 10.2 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               March 31, 1997.

10.7**         Form of Amended and Restated Vision Program Sponsor Agreement
               entered into as of March 29, 1995, between the Company and each
               of the following parties: Health Plus, Inc., Sanus Health Plan of
               New Jersey, Inc., Sanus Texas Health Plan, Inc., Sanus/New York
               Life Health Plan, Inc., Sanus Health Plan of Illinois, Inc. and
               Sanus Health Plan of Greater New York, Inc., incorporated by
               reference to Exhibit No. 10.3 to the Company's Annual Report on
               Form 10-K for the year ending 1995.

10.8**         Form of Amended and Restated Infusion Therapy Agreement entered
               into as of March 29, 1995, between the Company and each of the
               following parties: Health Plus, Inc., Sanus Texas Health Plan,
               Inc., Sanus/New York Life Health Plan, Inc., and Sanus Health
               Plan of Illinois, Inc., incorporated by reference to Exhibit No.
               10.4 to the Company's Annual Report on Form 10-K for the year
               ending 1995.

10.9**         Form of Infusion Therapy Agreement entered into as of March 29,
               1995, between the Company and each of the following parties:
               Sanus Health Plan of New Jersey, Inc. and Sanus Health
               Plan of Greater New York, Inc., incorporated by reference to
               Exhibit No. 10.5 to the Company's Annual Report on Form 10-K for
               the year ending 1995.

10.10          First Amendment to Vision Program Sponsor Agreement entered into
               as of September 1, 1995, between the Company and Sanus Health
               Plan of New Jersey, Inc., incorporated by reference to Exhibit
               No. 10.6 to the Company's Annual Report on Form 10-K for the year
               ending 1995.

10.11          First Amendment to the Amended and Restated Vision Program
               Sponsor Agreement entered into as of November 1, 1995, between
               the Company and Sanus Texas Health Plan, Inc., incorporated
               by reference to Exhibit No. 10.7 to the Company's Annual Report
               on Form 10-K for the year ending 1995.

10.12          Agreement dated January 1, 1989, as amended May 31, 1989, and
               January 1, 1991, between the Company and New York Life Insurance
               Company, incorporated by reference to Exhibit No. 10.20
               to the Registration Statement.

10.13          Third Amendment dated as of July 30, 1993, to the Agreement dated
               as of January 1, 1989, by and between the Company and New York
               Life Insurance Company, incorporated by reference to Exhibit No.
               10.16 to the Company's Quarterly Report on Form 10-Q for the
               quarter ending September 30, 1993.

10.14          Amended and Restated Managed Prescription Drug Program Agreement
               entered into as of September 1, 1995, between the Company and
               New York Life Insurance Company, incorporated by
               reference to Exhibit No. 10.24 to the Company's Annual Report on
               Form 10-K for the year ending 1995.

10.15**        First Amendment to Amended and Restated Managed Prescription Drug
               Program Agreement and Consent to Assignment dated as of January
               1, 1997, by and between the Company, New York Life Insurance
               Company and NYLCare Health Plans, Inc., incorporated by reference
               to Exhibit No. 10.1 to the Company's Quarterly Report on Form
               10-Q for the quarter ending March 31, 1997.

10.16          Quota-Share Reinsurance Agreement executed as of August 15, 1994,
               between New York Life Insurance Company and Great Plains
               Reinsurance Company, incorporated by reference to Exhibit 10.1 to
               the Company's Quarterly Report on Form 10-Q for the quarter
               ending September 30, 1994.

10.17          Amendment No. 1 to Quota-Share Reinsurance Agreement dated as of
               September 13, 1994, between New York Life Insurance Company and
               Great Plains Reinsurance Company, incorporated by reference to
               Exhibit 10.2 to the Company's Quarterly Report on Form 10-Q for
               the quarter ending September 30, 1994.

10.18          Joint Research Agreement dated June 28, 1994, by and between the
               Company, Sanus Corp.Health Systems and Schering Corporation,
               incorporated by reference to Exhibit 10.4 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending
               September 30, 1994.

10.19          Agreement dated May 7, 1992, between the Company and New York
               Life Insurance Company, incorporated by reference to Exhibit
               No. 10.26 to the Registration Statement.

10.20          Lease Agreement dated March 3, 1992, between Riverport, Inc. and
               Douglas Development Company--Irvine Partnership in commendam and
               the Company, incorporated by reference to Exhibit No. 10.21 to
               the Registration Statement.

10.21          First Amendment to Lease dated as of December 29, 1992, between
               Sverdrup/MDRC Joint Venture and the Company, incorporated by
               reference to Exhibit No. 10.13 to the Company's Quarterly
               Report on Form 10-Q for the quarter ending June 30, 1993.

10.22          Second Amendment to Lease dated as of May 28, 1993, between
               Sverdrup/MDRC Joint Venture and the Company, incorporated by
               reference to Exhibit No. 10.14 to the Company's Quarterly
               Report on Form 10-Q for the quarter ending June 30, 1993.

10.23          Third Amendment to Lease entered into as of October 15, 1993, by
               and between Sverdrup/MDRC Joint Venture and the Company,
               incorporated by reference to Exhibit No. 10.69 to the Company's
               Annual Report on Form 10-K for the year ending 1993.

10.24          Fourth Amendment to Lease dated as of March 24, 1994, by and
               between Sverdrup/MDRC Joint Venture and the Company,
               incorporated by reference to Exhibit No. 10.70 to the Company's
               Annual Report on Form 10-K for the year ending 1993.

10.25          Fifth Amendment to Lease made and entered into June 30, 1994,
               between Sverdrup/MDRC Joint Venture and the Company,
               incorporated by reference to Exhibit 10.1 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending June 30,
               1994.

10.26          Sixth Amendment to Lease made and entered into January 31, 1995,
               between Sverdrup/MDRC Joint Venture and the Company, incorporated
               by reference to Exhibit No. 10.70 to the Company's Annual Report
               on Form 10-K for the year ending 1994.

10.27          Seventh Amendment to Lease dated as of August 14, 1998, by and
               between Duke Realty Limited Partnership, by and through its
               general partner, Duke Realty Investments, Inc., and the Company,
               incorporated by reference to Exhibit No. 10.3 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending September
               30, 1998.

10.28          Eighth Amendment to Lease dated as of August 14, 1998, by and
               between Duke Realty Limited Partnership, by and through its
               general partner, Duke Realty Investments, Inc., and the Company,
               incorporated by reference to Exhibit No. 10.4 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending September
               30, 1998.

10.29*         Ninth Amendment to Lease dated as of February 19, 1999, by and
               between Duke Realty Limited Partnership, by and through its
               general partner, Duke Realty Investments, Inc., and the Company.

10.30          Single-Tenant Lease-Net entered into as of June 30, 1993,
               between James M. Chamberlain, Trustee of Chamberlain Family
               Trust dated September 21, 1979, and the Company, incorporated
               by reference to Exhibit No. 10.16 to the Company's Form 10-Q for
               the quarter ending June 30, 1993.

10.31          First Amendment to Single-Tenant Lease-Net entered into as of
               November 12, 1993, by and between James M. Chamberlain, Trustee
               of Chamberlain Family Trust, and the Company, incorporated by
               reference to Exhibit No. 10.74 to the Company's Annual Report on
               Form 10-K for the year ending 1993.

10.32          Earth City Industrial Office/Warehouse Lease Agreement dated as
               of August 19, 1996, by and between the Company and Louis
               Siegfried Corporation, incorporated by reference to Exhibit
               No. 10.1 to the Company's Quarterly Report on Form 10-Q for the
               quarter ending September 30, 1996.

10.33          Lease Agreement dated as of June 12, 1989, between Michael D.
               Brockelman and James S. Gratton, as Trustees under agreement
               dated April 17, 1980, and Health Care Services, Inc., an indirect
               subsidiary of the Company, incorporated by reference to Exhibit
               No. 10.7 to the Company's Quarterly Report on Form 10-Q for the
               quarter ending June 30, 1998.

10.34          Lease Agreement dated as of March 22, 1996, between Ryan
               Construction Company of Minnesota, Inc., and ValueRx Pharmacy
               Program, Inc., an indirect subsidiary of the Company,
               incorporated by reference to Exhibit No. 10.8 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending June 30,
               1998.

10.35          Lease Extension and Amendment Agreement dated as of July 24,
               1998, between Faith A. Griefen and ValueRX Pharmacy Program,
               Inc., an indirect subsidiary of the Company, incorporated by
               reference to Exhibit No. 10.1 to the Company's Quarterly Report
               on Form 10-Q for the quarter ending September 30, 1998.

10.36          Office Lease dated as of August 14, 1998 by and between Duke
               Realty Limited Partnership, by and through its general partner,
               Duke Realty Investments, Inc., and the Company, incorporated by
               reference to Exhibit No. 10.2 to the Company's Quarterly Report
               on Form 10-Q for the quarter ending September 30, 1998.

10.37*         Second Lease Amendment dated as of December 31, 1998 by and
               between Duke Realty Limited Partnership, by and through its
               general partner, Duke Realty Investments, Inc., and the Company.

10.38***       Express Scripts, Inc. 1992 Stock Option Plan, incorporated by
               reference to Exhibit No.10.23 to the Registration Statement.

10.39***       Express Scripts, Inc. Stock Option Plan for Outside Directors,
               incorporated by reference to Exhibit No. 10.24 to the
               Registration Statement.

10.40***       Express Scripts, Inc. 1994 Stock Option Plan, incorporated by
               reference to Exhibit No. 10.4 to the Company's Quarterly Report
               on Form 10-Q for the quarter ending June 30, 1994.

10.41***       Amended and Restated Express Scripts, Inc. 1992 Employee Stock
               Option Plan, incorporated by reference to Exhibit No. 10.78 to
               the Company's Annual Report on Form 10-K for the year
               ending 1994.

10.42***       Amended and Restated Express Scripts, Inc. Stock Option Plan for
               Outside Directors, incorporated by reference to Exhibit No.
               10.79 to the Company's Annual Report on Form 10-K for the year
               ending 1994.

10.43***       First Amendment to Express Scripts, Inc. Amended and Restated
               1992 Stock Option Plan for Outside Directors incorporated by
               reference to Exhibit A to the Company's Proxy Statement
               dated April 9, 1996.

10.44***       Amended and Restated Express Scripts, Inc. 1994 Stock Option
               Plan  incorporated by reference to Exhibit No. 10.80 to the
               Company's Annual Report on Form 10-K for the year
               ending 1994.

10.45***       First Amendment to Express Scripts, Inc. Amended and Restated
               1994 Stock Option Plan incorporated by reference to Exhibit A to
               the Company's Proxy Statement dated April 16, 1997.

10.46***       Second Amendment to Express Scripts, Inc. Amended and Restated
               1994 Stock Option Plan incorporated by reference to Exhibit A to
               the Company's Proxy Statement dated April 21, 1998.

10.47***       Employment Agreement dated April 30, 1992, between the Company
               and Barrett A. Toan (including form of Non-Qualified Stock
               Option Agreement), incorporated by reference to
               Exhibit No. 10.25 to the Registration Statement.

10.48***       Letter Agreement amending Employment Agreement dated
               February 28, 1996, from the Company to
               Barrett A. Toan, incorporated by reference to Exhibit No. 10.51
               to the Company's Annual Report on Form 10-K for the year ending
               1995.

10.49***       Form of Severance Agreement dated as of January 27, 1998,
               between the Company and each of the following individuals:
               Stuart L. Bascomb, Thomas M. Boudreau, Robert W. Davis, Linda L.
               Logsdon, David A. Lowenberg, and George Paz, and Patrick J.
               Byrne (agreement dated as of May 29, 1998), Michael S. Flagstad
               (agreement dated as of April 1, 1998), and Jean-Marc
               Quach (agreement dated as of May 18, 1998); incorporated by
               reference to Exhibit No. 10.70 to the Company's Annual Report
               on Form 10-K for the year ending December 31, 1997.

10.50          Credit Agreement dated as of April 1, 1998 among the Company,
               the Lenders listed therein and Bankers Trust Company, as Agent
               (the "Credit Agreement"), incorporated by reference to
               Exhibit No. 10.1 to the Company's Quarterly Report on Form 10-Q
               for the quarter ending June 30, 1998.

10.51          Company Pledge Agreement dated as of April 1, 1998 by the
               Company in favor of the Lenders listed in the Credit Agreement
               and Bankers Trust Company, as Agent incorporated by reference to
               Exhibit No. 10.2 to the Company's Quarterly Report on Form 10-Q
               for the quarter ending June 30, 1998.

10.52          Form of Subsidiary Guaranty dated as of April 1, 1998 in favor
               of the Lenders listed in the Credit Agreement and Bankers Trust
               Company, as Agent, by the following parties: Express Scripts
               Vision Corporation, PhyNet, Inc., IVTx, Inc., IVTx of Dallas,
               Inc., IVTx of Houston, Inc., ESI Canada Holdings, Inc., ESI
               Canada, Inc., Value Health, Inc., Managed Prescription Network,
               Inc., Prescription Drug Service, Inc., RxNet, Inc. of California,
               Denali Associates, Inc., ValueRx Northeast, Inc., MedCounter,
               Inc., Health Care Services, Inc., ValueRx, Inc., Cost Containment
               Corp. of America, Diagnostek, Inc., MedIntell Systems
               Corporation, ValueRx Pharmacy Program, Inc., ValueRx of Michigan,
               Inc., Diagnostek Pharmacy Services, Inc., Diagnostek Pharmacy,
               Inc., Diagnostek of Springfield, Inc., IPH, Inc., and MHI, Inc.,
               incorporated by reference to Exhibit No. 10.3 to the Company's
               Quarterly Report on Form 10-Q for the quarter ending June 30,
               1998.

10.53          Form of Subsidiary Pledge Agreement dated as of April 1, 1998 in
               favor of the Lenders listed in the Credit Agreement and Bankers
               Trust Company, as Agent, by the following parties: ESI Canada
               Holdings, Inc., Value Health, Inc., ValueRx, Inc., Diagnostek,
               Inc., ValueRx Pharmacy Program, Inc., Diagnostek Pharmacy
               Services, Inc., and IPH, Inc., incorporated by reference to
               Exhibit No. 10.4 to the Company's Quarterly Report on Form 10-Q
               for the quarter ending June 30, 1998.

10.54          First Amendment to Company Pledge Agreement dated as of April 24,
               1998, by the Company by the Company in favor of the Lenders
               listed in the Credit Agreement and Bankers Trust Company, as
               Agent, incorporated by reference to Exhibit No. 10.5 to the
               Company's Quarterly Report on Form 10-Q for the quarter ending
               June 30, 1998.

10.55          International Swap Dealers Association, Inc. Master Agreement
               dated as of April 3, 1998, between the Company and The First
               National Bank of Chicago, incorporated by reference to
               Exhibit No. 10.6 to the Company's Quarterly Report on Form 10-Q
               for the quarter ending June 30, 1998.

10.56***       Express Scripts, Inc. Employee Stock Purchase Plan incorporated
               by reference to Exhibit No. 4.1 to the Company's Registration
               Statement on Form S-8 filed December 29, 1998.

10.57***       Express Scripts, Inc. Executed Deferred Compensation Plan
               incorporated by reference to Exhibit No. 4.1 to the Company's
               Registration Statement on Form S-8 filed February 16, 1999.

21.1*          List of Subsidiaries.

23.1*          Consent of PricewaterhouseCoopers LLP.



27.1*          Financial Data Schedule (provided for the information of the U.S.
               Securities and Exchange Commission only).

- ------------------
*         Filed herein
**        Confidential treatment granted for certain portions of these
          exhibits.
***       Management contract or compensatory plan or arrangement.





                                  EXHIBIT 3.3

                            CERTIFICATE OF AMENDMENT
                                     OF THE
                          CERTIFICATE OF INCORPORATION
                                       OF
                              EXPRESS SCRIPTS, INC.

     Express  Scripts,  Inc. (the  "Corporation"),  a corporation  organized and
existing  under  and by virtue of the  General  Corporation  Law of the State of
Delaware, DOES HEREBY CERTIFY

     FIRST: That the Board of Directors of the Corporation at a meeting duly
called and held adopted resolutions proposing and declaring advisable an
amendment to the Certificate of Incorporation of the Corporation, as follows:

     RESOLVED,  that the Board of  Directors  hereby  proposes  and  declares it
advisable  that the  first  paragraph  of  Article  Four of the  Certificate  of
Incorporation of the Corporation be amended to read in its entirety as follows:

     4. The total number of shares of stock which the  Corporation has authority
to issue is  102,000,000  shares,  of which (i)  5,000,000  shares are preferred
stock,  par value $0.01 per share (the "Preferred  Stock"),  and (ii) 97,000,000
shares are  common  stock,  consisting  of  75,000,000  shares of Class A Common
Stock,  par value $0.01 per share (the "Class A Common  Stock"),  and 22,000,000
shares of Class B Common  Stock,  par value $0.01 per share (the "Class B Common
Stock").

     SECOND:  That thereafter at a meeting of stockholders duly called and held,
a  majority  of the votes of the  outstanding  Class A Common  Stock and Class B
Common Stock of the  Corporation  entitled to vote thereon voting  together as a
single  class,  and a majority  of the votes of the  outstanding  Class A Common
Stock and Class B Common  Stock  entitled  to vote  thereon  voting as  separate
classes, were voted in favor of the amendment.

     THIRD:  That  said  amendment  was  duly  adopted  in  accordance  with the
provisions  of  Section  242 of the  General  Corporation  Law of the  State  of
Delaware.

     IN WITNESS WHEREOF,  Express Scripts, Inc. has caused its corporate seal to
be hereunto  affixed and this  Certificate  to be signed by Barrett A. Toan, its
President and Chief Executive Officer,  and attested by Thomas M. Boudreau,  its
Secretary, this 3rd day of June, 1998.

                                    Express Scripts, Inc.

                                     By: /s/ Barrett A. Toan
                                         Barrett A. Toan, President and
                                         Chief Executive Officer

ATTEST:

[Corporate Seal]

/s/ Thomas M. Boudreau
Thomas M. Boudreau, Secretary



                                 EXHIBIT 10.29

                              NINTH LEASE AMENDMENT

     THIS NINTH LEASE  AMENDMENT  (the "Ninth  Amendment") is executed this 19th
day of February, 1999 by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana
limited  partnership,  ("Landlord"),  and  EXPRESS  SCRIPTS,  INC.,  a  Delaware
corporation, ("Tenant")

                              W I T N E S S E T H :

     WHEREAS,   Riverport,   Inc.  and  Douglas  Development  Company  -  Irvine
Partnership  in Commendam  (collectively,  the "Original  Landlord")  and Tenant
entered into a lease dated March 3, 1992  (including  all Exhibits,  Addenda and
Amendments   thereto,   the   "Lease")   for  a  certain   64,000   square  foot
office/warehouse  building located at 14042 Riverport Drive, St. Louis, Missouri
63043 (the "Building");

     WHEREAS, in November,  1992,  Original Landlord  transferred all its right,
title, and interest in the Building to Sverdrup/MDRC  Joint Venture  ("Successor
Landlord") and said Successor Landlord assumed all of Original Landlord's duties
and obligations under the Lease;

     WHEREAS,  Successor  Landlord and Tenant entered into a First  Amendment to
Lease dated  December 29, 1992 (the "First  Amendment"),  a Second  Amendment to
Lease dated May 28, 1993 (the "Second  Amendment"),  a Third  Amendment to Lease
dated  October 15, 1993 (the "Third  Amendment"),  a Fourth  Amendment  to Lease
dated March 24, 1994 (the "Fourth Amendment"),  a Fifth Amendment to Lease dated
June 30, 1994 (the "Fifth Amendment"),  a Sixth Amendment to Lease dated January
31, 1995 (the "Sixth Amendment"),  a Seventh Amendment to Lease dated August 14,
1998 (the "Seventh  Amendment"),  and an Eighth  Amendment to Lease dated August
14, 1998 (the "Eight Amendment");

     WHEREAS, pursuant to the Third Amendment, Landlord agreed to rent to Tenant
and Tenant agreed to lease from  Landlord an additional  12,365 square feet (the
"Additional Space");

     WHEREAS,  pursuant to the Fifth Amendment,  Landlord and Tenant agreed that
the  Additional  Space was no longer a part of the Premises,  and that the Third
Amendment  would  constitute  a lease of and by itself  (the  "Additional  Space
Lease")  standing  on its own terms  and  consisting  of all the same  terms and
conditions as were  contained in the Lease (except to the extent that such terms
and  conditions  relate  solely and  expressly to the Premises) and in the Third
Amendment;

     WHEREAS, on or about September 26, 1997, Successor Landlord transferred all
of its right,  title and interest under the Lease and in and to the Premises and
in and to the Additional Space Lease to Landlord;

     WHEREAS,  pursuant to the Seventh  Amendment,  the termination  date of the
Additional  Space Lease was extended  from  December 1, 1998 to the later of (i)
August  1,  1999 or (ii)  the  date  which  is sixty  (60)  days  following  the
Commencement  Date (as defined in the Office Lease  referenced and identified in
the Seventh Amendment) of the Office Lease;

     WHEREAS,  Tenant desires to extend the term of the  Additional  Space Lease
until December 31, 2000; and

     WHEREAS,  Landlord and Tenant  desire to amend  certain  provisions  of the
Additional Space Lease to reflect such extension;

     NOW  THEREFORE,  in  consideration  of the foregoing  premises,  the mutual
covenants  herein  contained  and each act  performed  hereunder by the parties,
Landlord and Tenant hereby enter into this Ninth Amendment and agree as follows:

     1.  TERMINATION  DATE. The termination  date of the Additional  Space Lease
(but said lease only) is hereby extended to December 31, 2000.

     2. ADDITIONAL  SPACE RENT.  Commencing on January 1, 2000, and on the first
day of each  calendar  month  thereafter  during the course of the tenancy  with
respect to the  Additional  Space,  Tenant shall pay to Landlord as Base Rent an
amount equal to $5,873.38 instead of $4,585.35.

     3. CONDITION OF PREMISES. Upon the expiration or earlier termination of the
Additional Space Lease,  Tenant shall return the Additional Space in broom clean
condition,  normal wear and tear, Tenant's improvements (as defined in the Third
Amendment),  other  non-structural  improvements and modifications,  and loss by
fire or other casualty excepted.

     4. OPTION TO EXTEND.

     A. GRANT AND  EXERCISE  OF  OPTION.  This  Option to Extend  applies to the
Additional  Space Lease only.  Provided  that (i) Tenant has not been in default
hereunder  at any  time  during  the Term of the  Additional  Space  Lease  (the
"Original  Additional Space Term"),  (ii) Tenant originally named herein remains
in possession of and has been  continuously  operating in the  Additional  Space
throughout  the  Original  Additional  Space Term and (iii)  Tenant's use of the
Additional  Space  remains  the same as  designated  in Section XI of the Lease,
Tenant  shall have one (1) option to extend the Original  Additional  Space Term
for one (1)  additional  period  of  three  (3)  years  (the  "Additional  Space
Extension  Term").  The Additional  Space  Extension Term shall be upon the same
terms and conditions  contained in the  Additional  Space Lease for the Original
Additional  Space Term except (i) Tenant  shall not have any  further  option to
extend and (ii) the  Minimum  Annual  Base Rent shall be  adjusted  as set forth
herein ("Rent  Adjustment").  Tenant shall exercise such option by delivering to
Landlord,  no later than April 1, 2000,  written  notice of  Tenant's  desire to
extend the Original Additional Space Term. Tenant's failure to properly exercise
such option shall waive it. If Tenant  properly  exercises its option to extend,
Landlord  shall notify Tenant in writing,  within twenty (20) days of receipt by
Landlord of Tenant's said notice, of Landlord's  proposed  Effective Market Base
Rent Rate (as hereinafter  defined) and Landlord's  proposed Minimum Annual Base
Rent for the Additional  Space  Extension  Term.  The Minimum  Monthly Base Rent
shall be an amount equal to  one-twelfth  (1/12) of the Minimum Annual Base Rent
for the Additional  Space  Extension Term and shall be paid at the same time and
in the same manner as provided in the Additional Space Lease. If Tenant properly
exercises  its option to extend,  Landlord and Tenant shall execute an amendment
to the Lease (or, at Landlord's  option, a new lease on the form then in use for
the  Building)  reflecting  the terms and  conditions  of the  Additional  Space
Extension Term.

     B. RENT  ADJUSTMENT.  The Minimum Annual Base Rent for the Additional Space
Extension  Term shall be an amount  equal to  ninety-five  percent  (95%) of the
projected  Effective Market Base Rent Rate, as at the  commencement  date of the
Additional Space Extension Term which said Effective Market Base Rent Rate shall
be the rate  charged to tenants  for space of  comparable  size,  location,  and
conditions in comparable property within a five (5) mile radius of the Building.
Said  Effective  Market  Base  Rent  Rate  shall  take  into  consideration  the
following:  location,  quality,  age,  common area factors,  finish  allowances,
rental abatement,  parking charges, lease assumptions,  moving allowances, space
planning  allowances,  refurbishment  allowances,  and any other  concession  or
inducement.  In addition, other consideration such as credit standing of Tenant,
lease term,  and any other issues that would be relevant in making a market rate
determination  should be considered.  If Landlord and Tenant should be unable to
agree  as to the  Effective  Market  Base  Rent  Rate for the  Additional  Space
Extension  Term within twenty (20) days of receipt by Tenant of Landlord's  said
notice,  then  Landlord  and Tenant  shall each select a  qualified  real estate
appraiser (as hereinafter  defined) to determine the Effective  Market Base Rent
Rate.  Said  appraisers  shall render their written  decision within twenty (20)
days  after the date of their  selection.  If the  difference  between  the high
appraisal  and  the  low  appraisal  is ten  percent  (10%)  or  less of the low
appraisal, then the Effective Market Base Rent Rate shall be the average between
the low  appraisal and the high  appraisal and the Minimum  Annual Base Rent for
the Additional Space Extension Term shall be ninety-five  percent (95%) thereof.
In the  event  said  difference  is in  excess of ten  percent  (10%),  then the
appraisers  shall mutually  select a third  appraiser who shall render a written
decision  of the  Effective  Market  Base Rent Rate  within  twenty (20) days of
his/her  selection.  The Minimum  Annual Base Rent during the  Additional  Space
Extension Term shall be ninety-five  percent (95%) of the Effective  Market Base
Rent Rate as established by the third appraiser;  provided,  however,  that said
Effective  Market  Base Rent Rate shall not be  greater  than the  initial  high
appraisal or be less than the initial low appraisal nor shall the Minimum Annual
Base Rent for the  Additional  Space  Extension  Term be less  than the  Minimum
Annual Base Rent payable by Tenant to Landlord as of the Termination Date of the
immediately  preceding Original Additional Space Term. In the event that the two
appraisers  fail or refuse to select a third  appraiser,  either  party may make
application,  upon written notice to the other, to the Chief Judge of the United
States District Court for the Eastern  District of Missouri,  Eastern  Division,
who shall  select  the third  appraiser.  Either  party  may,  within  three (3)
business days of the making of application to the Chief Judge,  submit a list of
not more than five (5) qualified (as herein  specified)  real estate  appraisers
for the guidance of the Chief Judge. Each party shall pay the appraiser selected
by it and the costs of the third  appraiser,  if any,  shall be borne equally by
Landlord  and Tenant.  If it shall  become  necessary  to select  appraisers  in
accordance with the terms of this Section 4.B, said  appraisers  shall be either
(i) a  disinterested  commercial real estate broker with at least ten (10) years
professional  experience  in the St.  Louis,  Missouri  metropolitan  industrial
market or (ii) a disinterested  person with at least ten (10) years professional
experience  in  commercial  real estate  appraisal  in the St.  Louis,  Missouri
metropolitan  area,  and a  member  in  good  standing  in at  least  one of the
following  professional  organizations:  The Society of Real  Estate  Appraisers
(holding  the  SREA  designation),  or the  American  Institute  of Real  Estate
Appraisers (holding the MAI designation).

     5. EXAMINATION OF AMENDMENT.  Submission of this instrument for examination
or signature to Tenant does not  constitute a reservation  or option,  and it is
not effective until execution by and delivery to both Landlord and Tenant.

     6. DEFINITIONS.  Except as otherwise provided herein, the capitalized terms
used in this Ninth Amendment shall have the definitions set forth in the Lease.

     7. INCORPORATION.  This Ninth Amendment shall be incorporated into and made
a part of the Additional Space Lease, and all provisions of the Additional Space
Lease not  expressly  modified or amended  hereby shall remain in full force and
effect.

     IN WITNESS  WHEREOF,  the parties  have caused this Ninth  Amendment  to be
executed on the day and year first above written.

                             LANDLORD:

                             DUKE REALTY LIMITED PARTNERSHIP,
                             an Indiana limited partnership

                             By:      Duke Realty Investments, Inc.,
                                      its General Partner
ATTEST:

/s/ James D. Echoff                    By: /s/ Ramsey F. Maune
Corporate Attorney                          Ramsey F. Maune
and Vice President                          Vice President and General Manager
                                            St. Louis Industrial Group

                              TENANT:

                              EXPRESS SCRIPTS, INC., a Delaware
                              corporation

ATTEST:                       By: /s/ Thomas M. Boudreau
                                   Thomas M. Boudreau
/s/ Keith J. Ebling                Senior Vice President and General Counsel
Secretary



STATE OF MISSOURI   )
                    ) SS:
COUNTY OF ST. LOUIS )

     Before me, a Notary  Public in and for said  County  and State,  personally
appeared  Thomas M.  Boudreau,  by me known  and by me known to be the Sr.  Vice
President of Express Scripts,  Inc., a Delaware corporation who acknowledged the
execution of the foregoing Ninth Amendment on behalf of said corporation.

     WITNESS my hand and Notarial Seal this 9th day of February, 1999.

                                        /s/ Kathleen M. Dolan
                                              Notary Public

                                             Kathleen M. Dolan
                                             (Printed Signature)

My Commission Expires: 4/14/2001

My County of Residence: St. Louis County

STATE OF MISSOURI   )
                    ) SS:
COUNTY OF ST. LOUIS )

     Before me, a Notary  Public in and for said  County  and State,  personally
appeared  Ramsey F. Maune,  by me known and by me known to be the Vice President
and  General   Manager-St.   Louis  Industrial  Group  of  Duke  Realty  Limited
Partnership,  an Indiana limited  partnership who  acknowledged the execution of
the foregoing Ninth Amendment on behalf of said corporation.

     WITNESS my hand and Notarial Seal this 19th day of February, 1999.


                                        /s/ Kathleen M. Wade
                                             Notary Public

                                        Kathleen M. Wade
                                        (Printed Signature)

My Commission Expires:5/4/2002

My County of Residence: St. Louis County




                                 EXHIBIT 10.37

                             SECOND LEASE AMENDMENT

     This SECOND LEASE AMENDMENT (the "Second Amendment") is executed as of this
31st day of December,  1998, by and between DUKE REALTY LIMITED PARTNERSHIP,  an
Indiana limited  partnership,  by and through its general  partner,  Duke Realty
Investments,  Inc., an Indiana corporation,  authorized to do and doing business
in the State of  Missouri,  as  Landlord  (hereinafter  "Landlord")  and EXPRESS
SCRIPTS,  INC., a Delaware  corporation,  authorized to do and doing business in
the State of Missouri, as Tenant (hereinafter "Tenant").

                              W I T N E S S E T H:

     WHEREAS,  Landlord and Tenant  entered into a certain Office Lease dated as
of August 14, 1998 for all of the space in that certain  Building (as defined in
said  Office  Lease)  which  Landlord  is  in  the  process  of  causing  to  be
constructed,  which said Office  Lease was  heretofore  amended by that  certain
First Lease Amendment dated as of November 5, 1998 (the "First  Amendment") (the
said  Office  Lease  and the  First  Amendment  being  hereinafter  referred  to
collectively as the "Lease"); and

     WHEREAS,  Landlord  and  Tenant  desire to  further  amend the Lease in the
limited respects hereinafter set forth.

     NOW,  THEREFORE,  in  consideration  of the premises,  the mutual covenants
herein contained and each act performed  hereunder by the parties,  Landlord and
Tenant hereby agree as follows:

     1. Except as otherwise  herein  specifically  provided,  terms used in this
Second Lease Amendment shall have the meaning set forth in the Lease.

     2. At the  beginning of the second and third  paragraphs  of Section  3.11,
INSURANCE,  the word "Landlord"  shall be substituted for the word "Tenant".  In
the tenth (10th) line of the second  paragraph of Section 3.11,  INSURANCE,  the
word "Landlord" shall be substituted for the word "Tenant". The last sentence of
the  second  paragraph  of  Section  3.11,  INSURANCE,  shall be  deleted in its
entirety. At the end of the fourth paragraph of Section 3.11, INSURANCE,  before
the  period  the words  "and  Tenant"  shall be  added.  At the end of the fifth
paragraph of Section 3.11, INSURANCE, the word "Tenant" shall be substituted for
the word "Landlord".  At the beginning of the first and third lines of the sixth
paragraph of Section 3.11,  INSURANCE,  the word "Landlord" shall be substituted
for the word "Tenant".  At the end of Section 3.11, INSURANCE shall be added the
following:  "The reasonable cost of insurance required by the provisions of this
Section  3.11,  INSURANCE to be provided by Landlord  shall be paid by Tenant to
Landlord  within  thirty  (30) days of  receipt  by Tenant  of a  statement,  in
reasonable detail, as Additional Rent."

     3. This Second  Amendment shall be incorporated  into and made apart of the
Lease.  All  provisions  of the Lease not expressly  modified or amended  hereby
shall remain in full force and effect.

     IN WITNESS WHEREOF,  the parties have caused this Second Lease Amendment to
be executed as of the day and year first written above.

LANDLORD:                             DUKE REALTY LIMITED PARTNERSHIP,
                                      an Indiana limited partnership

                                      By:    DUKE REALTY INVESTMENTS, INC.
                                             an Indiana corporation,
(SEAL)                                       its general partner


                                             By: /s/ Gregory Thurman
ATTEST:                                      W. Gregory Thurman
                                             Vice President and General Manager,
/s/ James D. Echkoff                         St. Louis Office Group
James D. Eckhoff
Vice President
and Corporate Attorney


TENANT:                                EXPRESS SCRIPTS, INC.,
                                       a Delaware corporation


(SEAL)                                  By:  /s/ Barrett Toan
                                             Barrett Toan, President

ATTEST:

/s/ Thomas M. Boudreau
Thomas M. Boudreau
Secretary


STATE OF MISSOURI   )
                    )  SS.
COUNTY OF ST. LOUIS )


     On this 12th day of February 1999, before me personally appeared W. GREGORY
THURMAN, to me personally known, who, being by me duly sworn, did say that he is
Vice  President  and General  Manager,  St.  Louis  Office  Group of DUKE REALTY
LIMITED PARTNERSHIP, an Indiana limited partnership, and general partner in DUKE
REALTY INVESTMENTS,  INC., an Indiana corporation,  and that the seal affixed to
the foregoing SECOND LEASE AMENDMENT is the corporate seal of said  corporation,
and that said  SECOND  LEASE  AMENDMENT  was signed and sealed on behalf of said
limited  partnership  and  said  corporation,  by  authority  of  its  Board  of
Directors,  and said W. GREGORY Thurman acknowledged said SECOND LEASE AMENDMENT
to be  the  free  act  and  deed  of  the  said  limited  partnership  and  said
corporation.

     IN WITNESS  WHEREOF,  I have  hereunto  set my hand and affixed my official
seal in the County and State aforesaid, the day and year first above written.


                                        /s/ Kathleen M. Wade
                                             Notary Public


STATE OF MISSOURI   )
                    ) SS.
COUNTY OF ST. LOUIS )


     On this 25th day of January  1999,  before me appeared  BARRETT TOAN, to me
personally  known, who, being by my duly sworn, did say that he is the President
of EXPRESS SCRIPTS,  INC., a corporation of the State of Delaware,  and that the
seal  affixed  to  the  foregoing  instrument  is the  corporate  seal  of  said
corporation,  and that said  instrument  was signed and sealed on behalf of said
corporation  by  authority  of its Board of  Directors;  and said  BARRETT  TOAN
acknowledged said instrument to be the free act and deed of said corporation.

     IN WITNESS  WHEREOF,  I have  hereunto  set my hand and affixed my official
seal in the County and State aforesaid, the day and year first above written.


                                             /s/ Kathleen M. Dolan
                                                 Notary Public






                                  Exhibit 21.1


SUBSIDIARY                         STATE OF INCORPORATION    D/B/A
- ----------                         ----------------------    -----
ESI Canada, Inc.                   New Brunswick, Canada     None
ESI Canada Holdings, Inc.          New Brunswick, Canada     None
Express Scripts Vision
    Corporation                    Delaware                  ESI Vision Care
IVTx, Inc.                         Delaware                  None
ESI/VRx Sales Development Co.      Delaware                  None
Great Plains Reinsurance Company   Arizona                   None
Practice Patterns Science, Inc.    Delaware                  None
Managed Prescription
    Network, Inc.                  Delaware                  Columbia Pharmacy
                                                                Solutions
Value Health, Inc.                 Delaware                  None
Health Care Services, Inc.         Pennsylvania              None
MHI, Inc.                          Nevada                    None
ValueRx, Inc.                      Delaware                  None
ValueRx of Michigan, Inc.          Michigan                  None
ValueRx Pharmacy Program, Inc.     Michigan                  None
YourPharmacy.com                   Delaware                  None




                                  Exhibit 23.1


                       Consent of Independent Accountants



     We hereby  consent to the  incorporation  by reference in the  Registration
Statements  on  Form  S-8  (Nos.  333-72441,  333-69855,  333-48779,  333-48767,
333-48765,  333-27983,  333-04291,  33-64094,  33-64278,  33-93106)  of  Express
Scripts,  Inc. of our report dated  February  12, 1999,  appearing on page 42 of
this Form 10-K/A.




/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP
St. Louis, Missouri
June 10, 1999




<TABLE> <S> <C>


<ARTICLE>                     5

<CIK>                         0000885721
<NAME>                        Express Scripts, Inc.
<MULTIPLIER>                                1,000
<CURRENCY>                                  U.S.

<S>                                     <C>
<PERIOD-TYPE>                                   3-MOS
<FISCAL-YEAR-END>                         DEC-31-1998
<PERIOD-START>                            OCT-01-1998
<PERIOD-END>                              DEC-31-1998
<EXCHANGE-RATE>                                     1
<CASH>                                        122,589
<SECURITIES>                                        0
<RECEIVABLES>                                 450,812
<ALLOWANCES>                                   17,806
<INVENTORY>                                    55,634
<CURRENT-ASSETS>                              656,907
<PP&E>                                        111,909
<DEPRECIATION>                                 34,410
<TOTAL-ASSETS>                              1,095,461
<CURRENT-LIABILITIES>                         539,296
<BONDS>                                             0
                               0
                                         0
<COMMON>                                          336
<OTHER-SE>                                    249,358
<TOTAL-LIABILITY-AND-EQUITY>                1,095,461
<SALES>                                       838,785
<TOTAL-REVENUES>                              838,785
<CGS>                                         764,404
<TOTAL-COSTS>                                 812,149
<OTHER-EXPENSES>                                    0
<LOSS-PROVISION>                                    0
<INTEREST-EXPENSE>                              6,437
<INCOME-PRETAX>                                21,752
<INCOME-TAX>                                    9,828
<INCOME-CONTINUING>                            11,924
<DISCONTINUED>                                      0
<EXTRAORDINARY>                                     0
<CHANGES>                                           0
<NET-INCOME>                                   11,924
<EPS-BASIC>                                     .35
<EPS-DILUTED>                                     .35



</TABLE>


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