EXPRESS SCRIPTS INC
S-3/A, 1999-05-07
SPECIALTY OUTPATIENT FACILITIES, NEC
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<PAGE>   1
 
   
      AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 7, 1999
    
 
   
                                                      REGISTRATION NO. 333-74613
    
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                            ------------------------
 
   
                                AMENDMENT NO. 1
    
   
                                       TO
    
 
                                    FORM S-3
                             REGISTRATION STATEMENT
                                     UNDER
                           THE SECURITIES ACT OF 1933
                            ------------------------
 
                             EXPRESS SCRIPTS, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
 
<TABLE>
<S>                                                 <C>
                     DELAWARE                                           43-1420563
 (STATE OR OTHER JURISDICTION OF INCORPORATION OR         (I.R.S. EMPLOYER IDENTIFICATION NUMBER)
                   ORGANIZATION)
</TABLE>
 
                             14000 RIVERPORT DRIVE
                        MARYLAND HEIGHTS, MISSOURI 63043
                                 (314) 770-1666
  (ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE, OF
                   REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)
 
                            ------------------------
 
                            THOMAS M. BOUDREAU, ESQ.
                         GENERAL COUNSEL AND SECRETARY
                             EXPRESS SCRIPTS, INC.
                             14000 RIVERPORT DRIVE
                        MARYLAND HEIGHTS, MISSOURI 63043
                                 (314) 770-1666
 (NAME, ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE,
                             OF AGENT FOR SERVICE)
 
                            ------------------------
 
                                   COPIES TO:
 
<TABLE>
<S>                                                 <C>
             VINCENT PAGANO, JR., ESQ.                             JAMES J. CLARK, ESQ.
            SIMPSON THACHER & BARTLETT                            CAHILL GORDON & REINDEL
               425 LEXINGTON AVENUE                                   80 PINE STREET
           NEW YORK, NEW YORK 10017-3954                         NEW YORK, NEW YORK 10005
                  (212) 455-2000                                      (212) 701-3000
</TABLE>
 
                            ------------------------
 
    APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:  As soon as
practicable after the effective date of this registration statement.
 
    If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box. [ ]
 
   
    If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act,
other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. [ ]
    
 
    If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering. [ ]
- ------------
 
    If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [ ]
- ------------
 
   
    If delivery of the prospectus is expected to be made pursuant to Rule 434
under the Securities Act, please check the following box. [ ]
    
 
                            ------------------------
 
   
    THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON ANY DATE OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL
FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION
STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(a) OF
THE SECURITIES ACT, OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME EFFECTIVE,
ON ANY DATE THE SECURITIES AND EXCHANGE COMMISSION, ACTING PURSUANT TO SECTION
8(a), MAY DETERMINE.
    
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
<PAGE>   2
 
THE INFORMATION IN THIS PROSPECTUS IS NOT COMPLETE AND MAY BE CHANGED. WE MAY
NOT SELL THESE SECURITIES UNTIL THE REGISTRATION STATEMENT FILED WITH THE
SECURITIES AND EXCHANGE COMMISSION IS EFFECTIVE. THIS PROSPECTUS IS NOT AN OFFER
TO SELL THESE SECURITIES AND IT IS NOT SOLICITING AN OFFER TO BUY THESE
SECURITIES IN ANY STATE WHERE THE OFFER OR SALE IS NOT PERMITTED.
 
                SUBJECT TO COMPLETION, DATED             , 1999
 
                                        SHARES
                             [EXPRESS SCRIPTS LOGO]
                              CLASS A COMMON STOCK
                            ------------------------
 
   
     We are selling      shares of our Class A common stock. We have granted the
underwriters an option to purchase a maximum of           additional shares of
our Class A common stock to cover over-allotments of shares.
    
 
   
     We have two classes of authorized common stock, our Class A and Class B
common stock. Our Class B common stock has ten votes per share, and our Class A
common stock has one vote per share. NYLIFE HealthCare Management, Inc. is the
holder of all of our outstanding Class B common stock. After this offering,
NYLIFE HealthCare will have      % of the combined voting power of our common
stock.
    
 
   
     Our Class A common stock is traded on The Nasdaq National Market under the
symbol "ESRX." On        , 1999, the last reported sale price for our Class A
common stock on The Nasdaq National Market was $     per share.
    
 
   
      INVESTING IN OUR CLASS A COMMON STOCK INVOLVES RISKS. SEE "RISK FACTORS"
                              BEGINNING ON PAGE 8.
    
 
<TABLE>
<CAPTION>
                                                          UNDERWRITING
                                              PRICE TO    DISCOUNTS AND         PROCEEDS TO
                                               PUBLIC      COMMISSIONS     EXPRESS SCRIPTS, INC.
                                              --------    -------------    ---------------------
<S>                                           <C>         <C>              <C>
Per Share...................................     $              $                    $
Total.......................................     $              $                    $
</TABLE>
 
   
     The shares of Class A common stock are offered by the several underwriters,
subject to conditions precedent described in an agreement between us and the
several underwriters. Delivery of the shares of Class A common stock will be
made on or about              , 1999.
    
 
     Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities or determined if this
prospectus is truthful or complete. Any representation to the contrary is a
criminal offense.
 
CREDIT SUISSE FIRST BOSTON
                     BT ALEX. BROWN
                                       MORGAN KEEGAN & COMPANY, INC.
 
                     Prospectus dated                , 1999
<PAGE>   3
 
                           -------------------------
 
   
                               TABLE OF CONTENTS
    
 
   
<TABLE>
<CAPTION>
                                      PAGE
                                      ----
<S>                                   <C>
PROSPECTUS SUMMARY..................    1
RISK FACTORS........................    8
USE OF PROCEEDS.....................   14
PRICE RANGE OF COMMON STOCK AND
  DIVIDEND POLICY...................   15
CAPITALIZATION......................   16
SELECTED FINANCIAL AND OPERATING
  DATA..............................   17
UNAUDITED CONSOLIDATED CONDENSED PRO
  FORMA FINANCIAL DATA..............   19
MANAGEMENT'S DISCUSSION AND ANALYSIS
  OF FINANCIAL CONDITION AND RESULTS
  OF OPERATIONS.....................   25
BUSINESS............................   37
</TABLE>
    
 
   
<TABLE>
<CAPTION>
                                      PAGE
                                      ----
<S>                                   <C>
MANAGEMENT..........................   53
PRINCIPAL STOCKHOLDERS..............   56
DESCRIPTION OF CAPITAL STOCK........   58
DESCRIPTION OF THE NEW CREDIT
  FACILITY..........................   60
UNDERWRITING........................   62
NOTICE TO CANADIAN RESIDENTS........   64
FORWARD-LOOKING STATEMENTS..........   65
WHERE YOU CAN FIND MORE
  INFORMATION.......................   67
LEGAL MATTERS.......................   68
EXPERTS.............................   68
INDEX TO FINANCIAL STATEMENTS.......  F-1
</TABLE>
    
 
                           -------------------------
 
     YOU SHOULD RELY ONLY ON THE INFORMATION CONTAINED IN THIS DOCUMENT OR TO
WHICH WE HAVE REFERRED YOU. WE HAVE NOT AUTHORIZED ANYONE TO PROVIDE YOU WITH
ANY DIFFERENT INFORMATION. THIS DOCUMENT MAY ONLY BE USED WHERE IT IS LEGAL TO
SELL THESE SECURITIES. THE INFORMATION IN THIS DOCUMENT MAY ONLY BE ACCURATE AS
OF THE DATE OF THIS DOCUMENT.
 
                                        i
<PAGE>   4
 
                               PROSPECTUS SUMMARY
 
   
     This summary highlights information contained elsewhere in this prospectus
and may not contain all of the information you should consider before investing
in the shares of Class A common stock offered by this prospectus. You should
read this entire prospectus carefully. You should also keep in mind the
following points as you read this prospectus:
    
 
   
- - Unless the context otherwise indicates, references in this document to "we,"
  "us" and "our" refer to Express Scripts, Inc. and its subsidiaries. References
  to "NYLIFE HealthCare" refer to NYLIFE HealthCare Management, Inc.
    
 
   
- - Unless we tell you otherwise, all information in this prospectus has been
  adjusted to reflect a two-for-one stock split of our common stock that
  occurred on October 30, 1998
    
 
   
- - Unless we tell you otherwise, the information in this prospectus assumes that
  the underwriters will not exercise their over-allotment option to purchase
            additional shares of our Class A common stock
    
 
   
- - Information regarding our relative size is based on estimates of our
  management in light of their experience in the industry
    
 
   
- - Membership counts may not be comparable between us and DPS, or between us and
  our competitors, although we believe they provide a reasonable estimation of
  the population we serve
    
 
                                  THE COMPANY
 
   
     We are the largest pharmacy benefit management company, commonly referred
to as a PBM, independent of pharmaceutical manufacturer or drug store ownership
in North America. PBMs coordinate the distribution of outpatient pharmaceuticals
through a combination of benefit management services, including retail drug card
programs and mail pharmacy services. We provide these services for health care
payors. We believe our independence from pharmaceutical manufacturer ownership
allows us to make unbiased formulary recommendations to our clients, balancing
both clinical efficacy and cost. We also believe our independence from drug
store ownership allows us to construct a variety of convenient and
cost-effective retail pharmacy networks for our clients, without favoring any
particular pharmacy chain.
    
 
   
     We are the third largest PBM in North America in terms of total members,
and we have one of the largest managed care membership bases of any PBM. Before
1998, our growth was driven almost exclusively by our ability to expand our
product offerings and increase our client and membership base through internally
generated growth. From 1992 through 1997, our net revenues and net income
increased at compound annual growth rates of 58% and 49%, respectively. While
our internal growth strategy remains a major focus, we have recently
complemented our internal growth strategy with two substantial acquisitions. In
April 1998, we acquired ValueRx, and in April 1999, we acquired Diversified
Pharmaceutical Services, or DPS. These acquisitions added to the scale of our
membership base, broadened our product offerings and enhanced our clinical
capabilities, systems and technologies. On a pro forma basis including this
offering, our net revenues and net income for 1998 would have been approximately
$3.4 billion and $57.1 million, respectively, excluding a $709.9 million
after-tax write-down of assets charge and a $1.0 million after-tax restructuring
charge.
    
                                        1
<PAGE>   5
 
   
     As of January 1, 1999, after giving effect to the DPS acquisition, we would
have served approximately 47.0 million members, including 10.5 million members
under DPS's contract with United HealthCare which will terminate without renewal
on May 31, 2000. Besides United HealthCare, some of our other large clients
include Aetna U.S. Healthcare, Oxford Health Plans and the State of New York
Empire Plan Prescription Drug Program.
    
 
   
     Our PBM services are primarily delivered through networks of retail
pharmacies that are under non-exclusive contract with us and through five mail
pharmacy service centers that we own and operate. Our largest retail pharmacy
network includes more than 52,000 retail pharmacies, representing more than 99%
of all retail pharmacies in the United States. In 1998, including ValueRx and
DPS on a pro forma basis, we processed approximately 284 million pharmacy claims
with estimated total drug spending of approximately $10 billion.
    
 
                                    INDUSTRY
 
     Prescription drugs represent the fastest growing component of health care
expenditures in the United States. Since 1990, pharmaceutical sales have grown
at a compound annual growth rate of approximately 9%, and the U.S. Health Care
Financing Administration projects a compound annual growth rate of approximately
10% through 2007. This growth is principally driven by new drug introductions,
increases in drug utilization rates and changes in drug strength, therapeutic
mix and dosage. In response to these trends, health benefit providers have been
seeking ways to better understand and control drug costs. PBMs help health
benefit providers to provide a cost-effective drug benefit and better understand
the impact of prescription drug utilization on total health care expenditures.
 
                                    STRATEGY
 
   
     Our strategy is to increase our membership base and grow profitably by
focusing on the following:
    
 
   
     - Generation of Sales to New Clients and Growth from Existing Clients.  Our
       predominant growth strategy is to pursue sales to new clients and
       generate growth in the membership base of existing clients. Our compound
       annual growth rate in members, excluding our recent acquisitions, is 48%
       since our initial public offering in 1992. The managed care market
       segment has experienced, and we believe will continue to experience,
       solid growth. We believe additional opportunities also exist in the large
       employer and union market segments. Growth within the membership base of
       existing clients is also important to our strategy. When our clients
       market their service offerings to their potential members, they generally
       market our prescription drug program as part of their offerings. As their
       client base grows, our membership base typically also grows. Our recently
       announced internet pharmacy service initiative, YourPharmacy.com and
       DrugDigest.org, will assist us in executing this strategy. By allowing us
       to communicate more effectively and efficiently with our existing
       members, we believe that we will be able to reduce our operating costs by
       utilizing on-line communication as opposed to more expensive call center
       operations and paper-based correspondence. We also plan to increase the
       utilization of our existing mail pharmacies, which processed over 7.4
       million prescriptions in 1998, to distribute prescription medications
       ordered through our Internet e-commerce site. In addition, we believe
       that sales of both pharmaceutical and non-
    
                                        2
<PAGE>   6
 
   
       pharmaceutical products to the non-member general public will help us
       attract new clients. Furthermore, based on our clinical capabilities,
       information databasing and established expertise in managing prescription
       drug usage, we believe DrugDigest.org will be a comprehensive and
       credible source of information on prescription and non-prescription
       medications.
    
 
   
     - Development and Sale of New Products and Services to Existing Clients and
       Drug Manufacturers.  We continue to emphasize the development and sale of
       new products and services as part of our PBM offerings to our existing
       clients, and we have begun marketing some of our products, such as
       research programs, to selected pharmaceutical manufacturers. We believe
       these products and services are necessary to compete effectively in the
       current business environment and to differentiate us from our competitors
       on a measure other than price. We believe a particular growth area in the
       PBM industry will be medical information management. We believe our
       majority owned subsidiary, Practice Patterns Science, is an industry
       leader in this area, having developed proprietary software to process and
       sort medical claims, prescription drug claims and clinical laboratory
       data for use by managed care organizations and other health care
       companies. Through our internet initiative we will also sell
       over-the-counter medications, health and beauty aids, vitamins and herbs
       to our existing clients.
    
 
   
     - Growth Through Strategic Acquisitions and Alliances.  During the past
       several years we have begun to supplement our strong internal growth with
       selected acquisitions of other PBMs and strategic alliances. Our
       objectives in pursuing acquisitions and alliances are to increase the
       scale of our business, expand our client base, increase our penetration
       of PBM markets and expand our product and service offerings. Our
       acquisition of ValueRx added approximately 10.0 million members, and our
       acquisition of DPS added approximately 23.5 million members.
    
 
                              RECENT DEVELOPMENTS
 
   
     On April 1, 1999, we acquired DPS from SmithKline Beecham and one of its
affiliates for $700 million in cash. With the addition of DPS, we have one of
the largest managed care membership bases of any PBM. In addition, the
acquisition provides us with enhanced clinical capabilities, systems and
technologies.
    
 
   
     In connection with our acquisition of DPS, we entered into a $1.05 billion
credit facility and a $150 million senior subordinated bridge credit facility to
finance the acquisition and to refinance all of our existing indebtedness.
    
 
   
     On March 29, 1999, we announced our plans to launch two Internet sites,
YourPharmacy.com and DrugDigest.org. YourPharmacy.com will serve as an online
drug store and offer both prescription and over-the-counter medications,
vitamins, herbs and health and beauty aids. DrugDigest.org will provide
information on a variety of medications, vitamins and herbs. Although both
internet sites will be available to anyone, we hope to benefit from the use of
the services by our existing membership base to enhance our mail pharmacy
service utilization, reduce our member service costs, diversify our revenue base
and enable users to make informed medication-related decisions.
    
 
     On February 1, 1999, we announced a three-and-a-half-year contract with
Blue Cross and Blue Shield of Massachusetts. Beginning in the second half of
1999, we will provide PBM services, including retail network and mail pharmacy
services, claims processing,
                                        3
<PAGE>   7
 
clinical management support and other related services to approximately 1.2
million members.
 
   
     On January 14, 1999, DPS announced a five-year contract with Oxford Health
Plans. Under the contract, we provide retail network, claims processing,
clinical management support and other related services to approximately 1.8
million members.
    
                           -------------------------
 
   
     We were incorporated in Missouri in 1986 and reincorporated in Delaware in
1992. Our principal executive offices are located at 14000 Riverport Drive,
Maryland Heights, Missouri 63043, and our phone number is (314) 770-1666.
Express Scripts(R) is our registered trademark. Our other trademarks include
"ExpressComp(R)", "ExpressReview(R)", "Express Therapeutics(R)", "IVTx(R)",
"PERx(R)", "PERxCare(R)", "PERxComp(R)", "PTE(R)", "ValueRx(R)" and "Value
Health, Inc.(R)". We also acquired several additional trademarks through our
acquisition of DPS.
    
                                        4
<PAGE>   8
 
                                  THE OFFERING
 
   
Class A common stock offered
    
   
  by us.........................           shares
    
 
   
Common stock to be outstanding
  after this offering...........
    
 
   
  Class A common stock..........           shares
    
 
   
  Class B common stock..........           shares
    
                                    -------------
 
   
  Total common stock............           shares
    
                                    -------------
- -------------
 
   
                                    Does not include as of March 1, 1999:
    
 
   
                                    - stock options and similar equity rights
                                      granted to employees and independent
                                      directors to purchase 2,858,752 shares of
                                      our Class A common stock, of which 866,700
                                      were exercisable
    
 
   
                                    - certain reserved shares of our Class A
                                      common stock for issuance in connection
                                      with certain strategic alliances; see
                                      "Business -- Acquisitions and Strategic
                                      Alliances"
    
 
   
                                    - reserved shares of our Class A common
                                      stock for our Employee Stock Purchase Plan
                                      and our Executive Deferred Compensation
                                      Plan; see Note 10 in our 1998 consolidated
                                      financial statements
    
 
   
Relative rights of holders of
our Class A and Class B common
  stock.........................    Our Class B common stock has ten votes per
                                    share and our Class A common stock has one
                                    vote per share. NYLIFE HealthCare is the
                                    holder of all our outstanding Class B common
                                    stock. Our Class B common stock
                                    automatically converts to our Class A common
                                    stock on a share-for-share basis upon
                                    transfer by NYLIFE HealthCare to any entity
                                    other than an affiliate of NYLIFE HealthCare
                                    and otherwise at the option of NYLIFE
                                    HealthCare. After this offering, NYLIFE
                                    HealthCare will have      % and the holders
                                    of Class A common stock will have   % of the
                                    combined voting power of our common stock.
                                    In addition, after this offering NYLIFE
                                    HealthCare will own      % and the holders
                                    of Class A common stock will own      % of
                                    our outstanding shares of common stock.
    
 
   
Use of proceeds.................    To repay some of our indebtedness, a
                                    substantial portion of which was incurred in
                                    connection with our acquisition of DPS.
    
 
   
The Nasdaq National Market
  symbol: ......................    ESRX
    
   
    
                                        5
<PAGE>   9
 
                      SUMMARY FINANCIAL AND OPERATING DATA
 
   
<TABLE>
<CAPTION>
                                                              YEAR ENDED DECEMBER 31,
                                       ---------------------------------------------------------------------
                                                                                                  UNAUDITED
                                                                                       ACTUAL     PRO FORMA
                                         1994       1995       1996        1997      1998(2)(3)   1998(4)(5)
                                       --------   --------   --------   ----------   ----------   ----------
                                                       (IN THOUSANDS, EXCEPT PER SHARE DATA)
<S>                                    <C>        <C>        <C>        <C>          <C>          <C>
STATEMENT OF OPERATIONS DATA:
Net revenues.........................  $384,504   $544,460   $773,615   $1,230,634   $2,824,872   $3,449,649
Gross profit.........................    46,353     66,177     88,733      111,467      239,875      488,809
Operating income (loss)..............    20,471     28,877     39,630       48,850       89,234     (942,167)
Interest income (expense), net.......       305        757      3,450        5,856      (12,994)     (56,559)
Net income (loss)....................    12,723     18,327     26,148       33,429       42,674     (653,766)
Basic earnings per share(1)..........     $0.43      $0.62      $0.81        $1.02        $1.29      $(17.39)
Diluted earnings per share(1)........     $0.42      $0.60      $0.80        $1.01        $1.27      $(17.12)
</TABLE>
    
 
   
<TABLE>
<CAPTION>
                                                                         DECEMBER 31, 1998
                                                        ---------------------------------------------------
                                                                                      UNAUDITED ACQUISITION
                                                                                          PRO FORMA AS
                                                                       UNAUDITED            ADJUSTED
                                                                      ACQUISITION           FOR THIS
                                                          ACTUAL      PRO FORMA(6)       OFFERING(6)(7)
                                                        ----------    ------------    ---------------------
                                                                          (IN THOUSANDS)
<S>                                                     <C>           <C>             <C>
BALANCE SHEET DATA:
Cash..................................................  $  122,589     $   74,508          $   74,508
Working capital.......................................     117,611        (51,466)            (50,169)
Total assets..........................................   1,095,461      2,027,762           2,024,519
 
  Short-term debt.....................................      54,000             --                  --
  Long-term debt, less current maturities.............     306,000      1,040,000             704,658
                                                        ----------     ----------          ----------
Total debt............................................     360,000      1,040,000             704,658
Stockholders' equity..................................     249,694        247,622             581,018
</TABLE>
    
 
   
<TABLE>
<CAPTION>
                                                                YEAR ENDED DECEMBER 31,
                                       -------------------------------------------------------------------------
                                                                                                      UNAUDITED
                                                                                           ACTUAL     PRO FORMA
                                         1994        1995         1996         1997       1998(2)      1998(4)
                                       --------   ----------   ----------   ----------   ----------   ----------
                                                                    (IN THOUSANDS)
<S>                                    <C>        <C>          <C>          <C>          <C>          <C>
SELECTED DATA:
Pharmacy benefit covered lives.......     5,700        8,100        9,900       12,600       22,900       46,400
Annual drug spending(8)..............  $716,000   $1,172,000   $1,636,000   $2,486,000   $4,495,000   $9,913,000
Pharmacy network claims
  processed..........................    26,323       42,871       57,838       73,164      113,177      275,534
Mail pharmacy prescriptions filled...     1,594        2,129        2,770        3,899        7,426        8,514
EBITDA(9)............................   $23,795      $33,258      $46,337      $59,320     $115,667     $225,550
Cash flows provided by operating
  activities.........................    $9,741      $11,500      $29,863      $52,503     $126,574           --
Cash flows used in investing
  activities.........................   $(6,348)     $(8,047)    $(64,808)    $(16,567)   $(426,052)          --
Cash flows provided by financing
  activities.........................      $314       $2,311      $48,652       $3,033     $357,959           --
</TABLE>
    
 
                                        6
<PAGE>   10
 
   
 (1) Earnings per share have been restated to reflect our two-for-one stock
     split effective October 30, 1998.
    
 
   
 (2) Includes our acquisition of ValueRx effective April 1, 1998.
    
 
   
 (3) Includes a corporate restructuring charge of $1,651, $1,002 after tax.
     Excluding this restructuring charge, our basic and diluted earnings per
     share would have been $1.32 and $1.30, respectively.
    
 
   
 (4) Adjusted to give pro forma effect to our acquisitions of ValueRx and DPS
     and the related financings, including this offering and the use of the
     estimated net proceeds from this offering, in each case as if it had
     occurred on January 1, 1998. The unaudited pro forma statement of
     operations data does not give effect to the after-tax write-off of $4,018
     in deferred financing fees related to the retirement of our $440,000 credit
     facility and $185,342 of the Term B loans from the $1,050,000 credit
     facility which would be recognized as an extraordinary item. In addition,
     any cost savings we may realize in connection with the integration of DPS
     are not reflected in the unaudited pro forma statement of operations data.
    
 
   
 (5) Includes a write-down of assets of $1,092,184, $709,920 after tax, and a
     corporate restructuring charge of $1,651, $1,002 after tax. Excluding these
     charges, our net income would have been $57,156 and our basic and diluted
     earnings per share would have been $1.52 and $1.50, respectively.
    
 
   
 (6) Adjusted to give pro forma effect to our acquisition of DPS and the related
     financings as if they occurred on December 31, 1998.
    
 
   
 (7) Adjusted to give effect to this offering and the use of the estimated net
     proceeds from this offering as if they occurred on December 31, 1998.
    
 
   
 (8) Annual drug spending is a measure of the gross aggregate dollar value of
     drug expenditures of all programs managed by us. The difference between
     annual drug spending and revenue reported by us is the effect of excluding
     from reported revenues:
    
 
   
     - the drug ingredient cost for those clients that have established their
       own pharmacy networks
    
 
   
     - the expenditures for drugs for companies on formulary-only programs
       managed by us
    
 
   
     - the co-pay portion of drug expenditures that are the responsibility of
       members of health plans serviced by us
    
 
   
     Therefore, annual drug spending provides a common basis to compare the drug
     expenditures managed by a company given differences in revenue recognition.
    
 
   
(9) EBITDA is earnings before interest, taxes, depreciation and amortization, or
    operating income plus depreciation and amortization. EBITDA is presented
    because it is a widely accepted indicator of a company's ability to incur
    and service indebtedness. EBITDA, however, should not be considered as an
    alternative to net income as a measure of operating performance or an
    alternative to cash flow as a measure of liquidity. In addition, our
    definition of EBITDA may not be comparable to that reported by other
    companies.
    
                                        7
<PAGE>   11
 
                                  RISK FACTORS
 
   
     In addition to the other information in this prospectus, the following
factors should be considered carefully in evaluating an investment in the shares
of Class A common stock offered by this prospectus.
    
 
FAILURE TO INTEGRATE VALUERX AND DPS COULD ADVERSELY AFFECT OUR BUSINESS
 
   
     Our acquisitions of ValueRx and DPS have significantly increased our
membership base and the complexity of our operations. In light of both
acquisitions, we have developed and begun to implement an integration plan to
address items such as:
    
 
     - retention of key employees
 
     - consolidation of administrative and other duplicative functions
 
     - coordination of sales, marketing, customer service and clinical functions
 
     - systems integration
 
     - new product and service development
 
     - client retention and other items
 
   
     While we have achieved many of our integration goals to date with respect
to the acquisition of ValueRx, some significant integration challenges remain,
including the complete integration of our information technology systems. We
cannot provide any assurance that our integration plan for ValueRx will
successfully address all aspects of our operations, or that we will continue to
achieve our integration goals. In the case of DPS, we cannot provide any
assurance that our integration plan will address all relevant aspects of DPS's
business or that we will be able to implement our integration plan successfully.
In addition, we assumed a certain level of client retention when deciding to
purchase ValueRx and DPS. Many clients have relatively short-term contracts, and
we cannot provide any assurance that we will be able to achieve our client
retention targets. Finally, although we conducted an extensive investigation in
evaluating our acquisitions of ValueRx and DPS, it is possible that we failed to
uncover or appropriately address material problems with ValueRx's or DPS's
operations or financial condition, or failed to discover contingent liabilities.
Any of the foregoing could materially adversely affect our results of operations
or financial condition.
    
 
FAILURE TO MANAGE AND MAINTAIN INTERNAL GROWTH COULD ADVERSELY AFFECT
OUR BUSINESS
 
     We have experienced rapid internal growth over the past several years. Our
ability to effectively manage and maintain this internal growth will require
that we continue to improve our financial and management information systems as
well as identify and retain key personnel. We can provide no assurance that we
will successfully meet these requirements or that we will have access to
sufficient capital to do so. Our internal growth is also dependent upon our
ability to attract new clients and achieve growth in the membership base of our
existing clients. If we are unable to continue our client and membership growth,
our results of operations and financial position could be materially adversely
affected.
 
   
COMPETITION IN THE PBM INDUSTRY COULD REDUCE OUR CLIENT MEMBERSHIP AND OUR
PROFIT MARGINS
    
 
     Pharmacy benefit management is a very competitive business. Our competitors
include several large and well-established companies which may have greater
financial, marketing and technological resources than we do. One major
competitor in the PBM business,
 
                                        8
<PAGE>   12
 
   
Merck-Medco Managed Care is owned by Merck & Co., a pharmaceutical manufacturer.
Another major competitor, PCS, is owned by Rite-Aid, a large retail pharmacy
chain. Both of these competitors may possess purchasing or other advantages over
us by virtue of their ownership, and could succeed in taking away some of our
clients. Consolidation in the PBM industry may also lead to increased
competition among a smaller number of large PBM companies. We also face
competition from Internet-based providers of pharmaceuticals such as
Drugstore.com and PlanetRx.com. We cannot predict what effect, if any, these
competitors may have on the marketplace or on our business.
    
 
   
     Over the last several years intense competition in the marketplace has
caused many PBMs, including us, to reduce the prices charged to clients for core
services and share a larger portion of the formulary fees and related revenues
received from drug manufacturers with clients. Increased price competition could
reduce our profit margins and have a material adverse effect on our results of
operations.
    
 
FAILURE TO RETAIN KEY CLIENTS AND NETWORK PHARMACIES COULD ADVERSELY AFFECT
   
OUR BUSINESS AND LIMIT OUR ACCESS TO RETAIL PHARMACIES
    
 
   
     We currently provide PBM services to approximately 8,500 clients, including
several large clients. Our contracts with clients generally do not have terms of
longer than three years and in some cases are terminable by either party on
relatively short notice. Our larger clients generally distribute requests for
proposals in advance of the expiration of their contracts. If several of these
large clients elect not to extend their relationship with us, and we are not
successful in generating sales to replace the lost business, our future business
and operating results could be materially adversely affected. In addition, we
believe the managed care industry is undergoing substantial consolidation, and
some of our managed care clients could be acquired by another party that is not
our client. In this case, our client may not renew its PBM contract with us.
    
 
   
     With the completion of our acquisition of DPS, United HealthCare became our
largest client. With approximately 10.5 million members, United HealthCare
accounts for approximately 22% of our membership base. DPS's contract with
United HealthCare will expire on May 24, 2000, and United HealthCare has
indicated it will be moving to another provider at that time. In our financial
analysis of the DPS acquisition, we assumed United HealthCare would not renew
its contract. However, if we are unable to reduce our costs on a basis
commensurate with our expectations and manage the transition of this large
client to another provider both efficiently and effectively, the termination of
this contract may materially adversely affect our business and results of
operations.
    
 
   
     Our largest national provider network consists of more than 52,000 retail
pharmacies, which represent more than 99% of the retail pharmacies in the United
States. However, the top 10 retail pharmacy chains represent approximately 41%
of the 52,000 pharmacies, with pharmacy chains representing even higher
concentrations in selected areas of the United States. Our contracts with retail
pharmacies, which are non-exclusive, are generally terminable by either party on
relatively short notice. If one or more of the top pharmacy chains elects to
terminate its relationship with us, our members' access to retail pharmacies and
our business could be significantly impaired. In addition, Rite-Aid recently
acquired one of our major PBM competitors, and other large pharmacy chains
either own PBMs today or could attempt to acquire a PBM in the future. Ownership
of PBMs by retail pharmacy chains could have material adverse effects on our
relationships with these pharmacy chains and on our business and results of
operations.
    
 
                                        9
<PAGE>   13
 
   
LOSS OF RELATIONSHIPS WITH PHARMACEUTICAL MANUFACTURERS AND CHANGES IN THE
REGULATION OF DISCOUNTS AND REBATES PROVIDED TO US BY PHARMACEUTICAL
MANUFACTURERS COULD DECREASE OUR PROFITS
    
 
   
     We maintain contractual relationships with numerous pharmaceutical
manufacturers which provide us with discounts, rebates or formulary fees. We
also provide various services for, or services which are funded by,
pharmaceutical manufacturers. These services include compliance, therapy
management and market research programs. These arrangements are generally
terminable by either party on relatively short notice. If several of these
arrangements are terminated or materially altered by the pharmaceutical
manufacturers, our operating results could be materially adversely affected. In
addition, discounts, rebates and formulary programs, as well as some of the
services we provide to the pharmaceutical manufacturers, have been the subject
of debate in federal and state legislatures and various other public forums.
Changes in existing laws or regulations, changes in interpretations of existing
laws or regulations or the adoption of new laws or regulations relating to any
of these discounts, rebates and formulary fees and programs, may materially
adversely affect our business.
    
 
   
     Patents covering many brand name drugs that currently have substantial
market share will expire over the next several years, and generic drugs will be
introduced that may substantially reduce the market share of these brand name
drugs. Manufacturers of generic drugs do not generally offer incentive payments
on their drugs to PBMs in the form of discounts, rebates or formulary fees and
programs. Although we expect new drugs with patent protection to be introduced
in the future, we can provide no assurance these drugs will capture a
significant share of the market such that our incentive payment revenues will
not be reduced.
    
 
   
PENDING AND FUTURE LITIGATION COULD MATERIALLY AFFECT OUR RELATIONSHIPS WITH
PHARMACEUTICAL MANUFACTURERS OR SUBJECT US TO SIGNIFICANT MONETARY DAMAGES
    
 
   
     Since 1993, over 100 separate lawsuits have been filed by retail pharmacies
against drug manufacturers, wholesalers and PBMs challenging brand name drug
pricing practices under various state and federal antitrust laws. Some of these
lawsuits were consolidated into a nationwide class action, while others remained
as individual suits. The class action defendants have either settled the claims
against them or have had the claims dismissed. Several of the individual suits
are ongoing. We are not a party to any of these proceedings, and to date we do
not believe any of the related settlements have had a material adverse effect on
our business. However, we cannot provide any assurance that the terms of the
settlements will not materially adversely affect us in the future or that we
will not be made a party to any separate lawsuit. In addition, we cannot predict
the outcome or possible ramifications to our business of the cases in which the
plaintiffs are trying their claims separately.
    
 
   
     Our PBM operations, including the dispensing of pharmaceutical products by
our mail pharmacies, the services rendered in connection with our formulary
management and informed decision counseling services and the products and
services provided in connection with our infusion therapy programs, including
the associated nursing services, have subjected us and may subject us in the
future to litigation and liability for damages. We believe our insurance
protection is adequate for our present operations, but we cannot provide any
assurance that we will be able to maintain our professional and general
liability insurance coverage in the future or that insurance coverage will be
available on acceptable terms to cover any or all potential product or
professional liability claims. A successful product or professional liability
claim in excess of our insurance coverage could have a material adverse effect
on our business.
    
 
                                       10
<PAGE>   14
 
   
CHANGES IN STATE AND FEDERAL REGULATIONS COULD RESTRICT OUR ABILITY TO CONDUCT
OUR BUSINESS
    
 
     Numerous state and federal laws and regulations affect our business and
operations. These laws and regulations include, but are not necessarily limited
to:
 
   
     - health care fraud and abuse laws and regulations, which prohibit illegal
       referral and other payments
    
 
   
     - Employee Retirement Income Security Act of 1974 and related regulations,
       which regulate many health care plans
    
 
   
     - mail pharmacy laws and regulations
    
 
   
     - privacy and confidentiality laws and regulations
    
 
     - proposed comprehensive state PBM regulatory legislation
 
   
     - consumer protection laws and regulations
    
 
   
     - pharmacy network access laws, including "any willing provider" and "due
       process" legislation, that regulate aspects of our pharmacy network
       contracts
    
 
     - legislation imposing benefit plan design restrictions, which limit how
       our clients can design their drug benefit plans
 
   
     - various licensure laws, such as managed care and third party
       administrator licensure laws
    
 
   
     - drug pricing legislation, including "most favored nation" pricing and
       "unitary pricing" legislation
    
 
   
     - Medicare prescription drug coverage proposals
    
 
     - other Medicare and Medicaid reimbursement regulations
 
   
     - potential regulation of the PBM industry by the U.S. Food and Drug
       Administration
    
 
   
     We believe we are operating our business in substantial compliance with all
existing legal requirements material to the operation of our business. There
are, however, significant uncertainties regarding the application of many of
these legal requirements to our business, and we cannot provide any assurance
that a regulatory agency charged with enforcement of any of these laws or
regulations will not interpret them differently or, if there is an enforcement
action brought against us, that our interpretation would prevail. In addition,
there are numerous proposed health care laws and regulations at the federal and
state levels, many of which could materially affect our ability to conduct our
business or adversely affect our results of operations. We are unable to predict
what additional federal or state legislation or regulatory initiatives may be
enacted in the future relating to our business or the health care industry in
general, or what effect such legislation or regulations might have on us. We
also cannot provide any assurance that federal or state governments will not
impose additional restrictions or adopt interpretations of existing laws that
could have a material adverse effect on our business or results of operations.
    
 
   
EFFORTS TO REDUCE HEALTH CARE COSTS AND ALTER HEALTH CARE FINANCING PRACTICES
COULD ADVERSELY AFFECT OUR BUSINESS
    
 
     Efforts are being made in the United States to control health care costs,
including prescription drug costs, in response to, among other things, increases
in prescription drug utilization rates and drug prices. If these efforts are
successful or if prescription drug utilization rates were to decrease
significantly, our business and results of operations could be materially
adversely affected.
 
                                       11
<PAGE>   15
 
     We have designed our business to compete within the current structure of
the U.S. health care system. Changing political, economic and regulatory
influences may affect health care financing and reimbursement practices. If the
current health care financing and reimbursement system changes significantly,
our business could be materially adversely affected. Congress is currently
considering proposals to reform the U.S. health care system. These proposals may
increase governmental involvement in health care and PBM services, and otherwise
change the way our clients do business. Health care organizations may react to
these proposals and the uncertainty surrounding them by reducing or delaying
purchases of cost control mechanisms and related services that we provide. We
cannot predict what effect, if any, these proposals may have on our business.
Other legislative or market-driven changes in the health care system that we
cannot anticipate could also materially adversely affect our business.
 
   
FAILURE TO SUCCESSFULLY ADDRESS THE YEAR 2000 ISSUE COULD ADVERSELY AFFECT OUR
BUSINESS
    
 
   
     Our business relies heavily on computers and other information systems
technology. In 1995, we began addressing the "year 2000" issue, which generally
refers to the inability of computer systems to properly recognize calendar dates
beyond December 31, 1999.
    
 
   
     We believe that with appropriate modifications to our existing computer
systems, updates by our vendors and trading partners and conversion to new
software in the ordinary course of our business, the year 2000 issue will not
pose material operational problems for us. However, if the conversions are not
completed in a proper and timely manner by all affected parties, or if our logic
for communicating with noncompliant systems is ineffective, the year 2000 issue
could result in material adverse operational and financial consequences to us.
We cannot provide any assurance that our efforts, or those of our vendors and
trading partners, will be successful in addressing the year 2000 issue. In
addition, while DPS has represented to us that it has implemented a year 2000
plan for upgrading its computer systems and communicated with its vendor/trading
partners regarding these partners' year 2000 compliance, we cannot predict
whether this plan will adequately address all of DPS's year 2000 issues or
whether DPS's vendors/trading partners will adequately address their year 2000
issues. Failure by DPS or its vendors/trading partners to adequately address the
year 2000 issue could have a material adverse effect on our business and results
of operations.
    
 
LOSS OF KEY MANAGEMENT COULD ADVERSELY AFFECT OUR BUSINESS
 
   
     Our success is materially dependent upon our key managers and, in
particular, upon the continued services of Barrett A. Toan, our President and
Chief Executive Officer. Our future operations could be materially adversely
affected if the services of Mr. Toan cease to be available. We and Mr. Toan are
parties to an employment agreement which currently extends to March 31, 2002,
and which automatically extends for an additional one year on April 1, 2001, and
on each April 1 thereafter unless either party gives notice of termination at
least 30 days prior to such April 1. As of the date hereof, neither we nor Mr.
Toan has given this notice.
    
 
   
NEW YORK LIFE INSURANCE COMPANY CAN CONTROL OUR BUSINESS AND LIMIT OUR ABILITY
    
   
TO ENTER INTO SELECTED BUSINESS TRANSACTIONS
    
 
   
     We have two classes of authorized common stock: Class A and Class B common
stock. Our Class B common stock is entirely owned by NYLIFE HealthCare, an
indirect subsidiary of New York Life Insurance Company. Each share of our Class
A common stock has one vote per share, and each share of our Class B common
stock has ten votes
    
 
                                       12
<PAGE>   16
 
   
per share. After giving effect to this offering, NYLIFE HealthCare will have
approximately      % of the combined voting power of our common stock. NYLIFE
HealthCare could reduce its Class B common stock ownership to represent slightly
less than 10% of the total outstanding shares of our common stock and still
control a majority of the voting power of our common stock. Without regard to
the votes of our public stockholders, NYLIFE HealthCare can:
    
 
   
     - elect or remove all our directors
    
 
   
     - amend our certificate of incorporation, except where the separate
       approval of the holders of our Class A common stock is required by law
    
 
     - accept or reject a merger, sale of assets or other major corporate
       transaction
 
   
     - accept or reject any proposed acquisition of us
    
 
   
     - determine the amount and timing of dividends paid to itself and holders
       of our Class A common stock
    
 
   
     - except in limited circumstances, control our management and operations
       and decide all matters submitted for a stockholder vote
    
 
   
FUTURE SALES OR ISSUANCES OF SHARES COULD ADVERSELY AFFECT OUR SHARE PRICE
    
 
   
     As of March 1, 1999, in addition to the           shares of our Class A
common stock offered by this prospectus,           shares of our Class A common
stock are issuable upon exercise of outstanding stock options under our Employee
Stock Purchase Plan and our Executive Deferred Compensation Plan and
          shares of our Class B common stock are eligible for sale by NYLIFE
HealthCare pursuant to Rule 144 under the Securities Act, subject to the volume
and other limitations contained in Rule 144. Our Class B common stock will
automatically convert into a like number of shares of our Class A common stock
upon transfer by NYLIFE HealthCare to any entity other than an affiliate of
NYLIFE HealthCare or otherwise at the option of NYLIFE HealthCare. Under the
terms of various strategic alliances, we may also be obligated to issue up to
5,807,368 additional shares of our Class A common stock to our strategic
partners upon the achievement by them of various membership and claims targets
or the exercise by them of warrants.
    
 
   
     Any issuance of additional shares of our Class A common stock, including
those issuable in connection with our existing obligations, could result in a
decrease in the market price of our Class A common stock.
    
 
   
     We and some of our directors, officers and stockholders, including NYLIFE
HealthCare, have agreed not to offer, sell, contract to sell, announce an
intention to sell, pledge or otherwise dispose of, directly or indirectly, or,
in our case, file with the SEC a registration statement under the Securities Act
relating to any additional shares of our common stock or securities convertible
into or exchangeable or exercisable for any shares of our common stock, without
the prior written consent of Credit Suisse First Boston Corporation for a period
of 90 days after the date of this prospectus.
    
 
                                       13
<PAGE>   17
 
                                USE OF PROCEEDS
 
   
     The net proceeds to us from the sale of the           shares of our Class A
common stock offered by this prospectus are estimated to be $          , or
$          if the underwriters exercise their over-allotment option in full, at
an assumed offering price per share of $          and after deducting estimated
underwriting discounts and commissions and offering expenses payable by us. The
net proceeds of this offering will be used to repay our $150 million senior
subordinated bridge credit facility and part of the Term B Loan under our $1.05
billion credit facility. Our $150 million senior subordinated bridge credit
facility and $1.05 billion credit facility were entered into in connection with
our acquisition of DPS and the refinancing of all of our existing indebtedness.
See "Management's Discussion and Analysis of Financial Condition and Results of
Operations -- Liquidity and Capital Resources." The Term B Loan under our $1.05
billion credit facility matures on March 31, 2007 and, as of May 1, 1999, has an
interest rate of 8.375%. See "Description of the New Credit Facility." Our $150
million senior subordinated bridge credit facility matures one year after its
closing date unless previously converted to a term loan, which would mature ten
years after its closing date, and, as of May 1, 1999, has an interest rate of
9.97%.
    
 
                                       14
<PAGE>   18
 
                PRICE RANGE OF COMMON STOCK AND DIVIDEND POLICY
 
   
     Our Class A common stock has been traded on The Nasdaq National Market
under the symbol "ESRX" since June 9, 1992. The high and low prices of our Class
A common stock, as reported by The Nasdaq National Market, are set forth below
for the periods indicated. These prices reflect the two-for-one split on October
30, 1998, in the form of a 100% stock dividend to holders of record on October
20, 1998.
    
 
   
<TABLE>
<CAPTION>
                                                              HIGH        LOW
                                                            --------    -------
<S>                                                         <C>         <C>
1997
First Quarter.............................................  $ 19.125    $15.625
Second Quarter............................................  $ 24.500    $16.375
Third Quarter.............................................  $ 27.250    $20.750
Fourth Quarter............................................  $ 32.375    $25.313
1998
First Quarter.............................................  $ 42.750    $27.000
Second Quarter............................................  $ 45.000    $35.500
Third Quarter.............................................  $ 45.250    $31.625
Fourth Quarter............................................  $ 69.000    $33.875
1999
First Quarter.............................................  $105.500    $59.125
Second Quarter (through May 4, 1999)......................  $ 91.000    $60.625
</TABLE>
    
 
   
     Our Class B common stock has no established public trading market, but
these shares will automatically convert, on a share for share basis, to our
Class A common stock upon transfer by NYLIFE HealthCare to any entity other than
an affiliate of NYLIFE HealthCare or otherwise at the option of NYLIFE
HealthCare.
    
 
   
     Our board of directors has not declared any cash dividends since our
initial public offering in 1992. Our board of directors does not currently
intend to declare any cash dividends in the foreseeable future. The terms of our
$1.05 billion credit facility restrict our ability to declare or pay cash
dividends.
    
 
                                       15
<PAGE>   19
 
                                 CAPITALIZATION
 
   
     The following table sets forth our capitalization as of December 31, 1998,
on a pro forma basis to give effect to our acquisition of DPS and the related
financings, and on a pro forma as adjusted basis to reflect the sale of
4,500,000 shares of our Class A common stock offered by this prospectus and the
receipt of the estimated $335,342,000 in net proceeds from this offering,
assuming an offering price of $78.375 per share and after deducting estimated
underwriting discounts and commissions and other offering expenses payable by
us.
    
 
   
<TABLE>
<CAPTION>
                                                                                          UNAUDITED
                                                                                         ACQUISITION
                                                                                          PRO FORMA
                                                                         UNAUDITED       AS ADJUSTED
                                                                        ACQUISITION       FOR THIS
                                                           ACTUAL        PRO FORMA        OFFERING
                                                         ----------    -------------    -------------
                                                         (IN THOUSANDS, EXCEPT SHARE AND NET DEBT TO
                                                                   NET CAPITALIZATION DATA)
<S>                                                      <C>           <C>              <C>
Cash...................................................   $122,589       $   74,508       $   74,508
                                                          ========       ==========       ==========
Short-term debt:
  Current maturities of long-term debt.................   $ 54,000       $       --       $       --
                                                          --------       ----------       ----------
Long-term debt:
  Credit facility:
    Revolving debt.....................................         --          140,000          140,000
    Term debt..........................................    306,000          750,000          564,658
  Senior subordinated bridge credit facility...........         --          150,000               --
                                                          --------       ----------       ----------
    Total long-term debt...............................    306,000        1,040,000          704,658
                                                          --------       ----------       ----------
    Total debt.........................................   $360,000       $1,040,000       $  704,658
                                                          ========       ==========       ==========
Stockholders' equity:
  Preferred stock, $.01 per share, 5,000,000 shares
    authorized, and no shares issued and outstanding...   $     --       $       --       $       --
  Class A common stock, $.01 par value, 75,000,000
    shares authorized, 18,610,000 shares issued and
    outstanding and 23,110,000 shares issued and
    outstanding as adjusted(1).........................        186              186              231
  Class B common stock, $.01 par value, 22,000,000
    shares authorized, 15,020,000 shares issued and
    outstanding........................................        150              150              150
  Additional paid-in-capital...........................    110,099          110,099          445,396
  Accumulated other comprehensive income...............        (74)             (74)             (74)
  Retained earnings....................................    146,322          144,250          142,304
                                                          --------       ----------       ----------
                                                           256,683          254,611          588,007
 
  Class A common stock in treasury at cost, 475,000
    shares.............................................     (6,989)          (6,989)          (6,989)
                                                          --------       ----------       ----------
  Total stockholders' equity...........................   $249,694       $  247,622       $  581,018
                                                          ========       ==========       ==========
Net capitalization.....................................   $487,105       $1,213,114       $1,211,168
                                                          ========       ==========       ==========
Net debt to net capitalization(2)......................       48.7%            79.6%            52.0%
                                                          ========       ==========       ==========
</TABLE>
    
 
- -------------------------
 
   
(1) Does not include as of March 1, 1999:
    
 
   
    - stock options and similar equity rights granted to employees and
      independent directors to purchase 2,858,752 shares of our Class A common
      stock, of which 866,700 were exercisable
    
 
   
    - reserved shares of our Class A common stock for issuance in connection
      with strategic alliances; see "Business -- Acquisitions and Strategic
      Alliances"
    
 
   
    - reserved shares of our Class A common stock for our Employee Stock
      Purchase Plan and our Executive Deferred Compensation Plan; see Note 10 in
      our 1998 consolidated financial statements
    
 
   
(2) Net debt reflects total debt less cash.
    
 
                                       16
<PAGE>   20
 
                     SELECTED FINANCIAL AND OPERATING DATA
 
   
     The following table sets forth our selected financial and operating data
for the five years ended December 31, 1998. The financial data, excluding the
selected data, for the fiscal years ended December 31, 1996, 1997 and 1998 have
been derived from our consolidated financial statements included in this
prospectus which have been audited by PricewaterhouseCoopers LLP, independent
accountants. The financial data, excluding the selected data, for the fiscal
years ended December 31, 1994 and 1995 have been derived from our consolidated
financial statements not included in this prospectus which have been audited by
PricewaterhouseCoopers LLP.
    
 
   
     The data set forth below should be read in conjunction with the report of
PricewaterhouseCoopers LLP, our consolidated financial statements and related
notes and "Management's Discussion and Analysis of Financial Condition and
Results of Operations" included elsewhere in this prospectus.
    
 
   
<TABLE>
<CAPTION>
                                                                    YEAR ENDED DECEMBER 31,
                                                  ------------------------------------------------------------
                                                    1994        1995         1996         1997       1998(2)
                                                  --------   ----------   ----------   ----------   ----------
                                                             (IN THOUSANDS, EXCEPT PER SHARE DATA)
<S>                                               <C>        <C>          <C>          <C>          <C>
STATEMENT OF OPERATIONS DATA:
Net revenues....................................  $384,504     $544,460     $773,615   $1,230,634   $2,824,872
Costs and expenses:
  Cost of revenues..............................   338,151      478,283      684,882    1,119,167    2,584,997
  Selling, general and administrative...........    25,882       37,300       49,103       62,617      148,990
  Corporate restructuring.......................        --           --           --           --        1,651
                                                  --------   ----------   ----------   ----------   ----------
                                                   364,033      515,583      733,985    1,181,784    2,735,638
                                                  --------   ----------   ----------   ----------   ----------
Operating income................................    20,471       28,877       39,630       48,850       89,234
Interest income (expense), net..................       305          757        3,450        5,856      (12,994)
                                                  --------   ----------   ----------   ----------   ----------
Income before income taxes......................    20,776       29,634       43,080       54,706       76,240
Provision for income taxes......................     8,053       11,307       16,932       21,277       33,566
                                                  --------   ----------   ----------   ----------   ----------
Net income......................................   $12,723      $18,327      $26,148      $33,429      $42,674
                                                  ========   ==========   ==========   ==========   ==========
Earnings per share(1):
  Basic.........................................     $0.43        $0.62        $0.81        $1.02        $1.29
  Diluted.......................................     $0.42        $0.60        $0.80        $1.01        $1.27
Weighted average shares outstanding(1):
  Basic.........................................    29,588       29,560       32,160       32,713       33,105
  Diluted.......................................    30,293       30,545       32,700       33,122       33,698
BALANCE SHEET DATA:
Cash............................................    $5,742      $11,506      $25,211      $64,155     $122,589
Working capital.................................    38,082       58,653      128,259      166,062      117,611
Total assets....................................   108,922      164,088      300,425      402,508    1,095,461
  Short-term debt...............................        --           --           --           --       54,000
  Long-term debt, less current maturities.......        --           --           --           --      306,000
Total debt......................................        --           --           --           --      360,000
Stockholders' equity............................    52,485       77,379      164,090      203,701      249,694
SELECTED DATA:
Pharmacy benefit covered lives..................     5,700        8,100        9,900       12,600       22,900
Annual drug spending(3).........................  $716,000   $1,172,000   $1,636,000   $2,486,000   $4,495,000
Pharmacy network claims processed...............    26,323       42,871       57,838       73,164      113,177
Mail pharmacy prescriptions filled..............     1,594        2,129        2,770        3,899        7,426
EBITDA(4).......................................   $23,795      $33,258      $46,337      $59,320     $115,667
Cash flows provided by operating activities.....    $9,741      $11,500      $29,863      $52,503     $126,574
Cash flows used in investing activities.........   $(6,348)     $(8,047)    $(64,808)    $(16,567)   $(426,052)
Cash flows provided by financial activities.....      $314       $2,311      $48,652       $3,033     $357,959
</TABLE>
    
 
                                       17
<PAGE>   21
 
- -------------------------
(1) Earnings per share and weighted average shares outstanding have been
    restated to reflect the two-for-one stock split effective October 30, 1998.
 
   
(2) Includes our acquisition of ValueRx effective April 1, 1998. Also includes a
    corporate restructuring charge in 1998 of $1,651, $1,002 after tax.
    Excluding this restructuring charge, our basic and diluted earnings per
    share would have been $1.32 and $1.30, respectively.
    
 
   
(3) Annual drug spending is a measure of the gross aggregate dollar value of
    drug expenditures of all programs managed by us. The difference between
    annual drug spending and revenue reported by us is the combined effect of
    excluding from reported revenues:
    
 
   
    - the drug ingredient cost for those clients that have established their own
      pharmacy networks
    
 
   
    - the expenditures for drugs for companies on formulary-only programs
      managed by us
    
 
   
    - the co-pay portion of drug expenditures that are the responsibility of
      members of health plans serviced by us
    
 
   
    Therefore, annual drug spending provides a common basis to compare the drug
    expenditures managed by a company given differences in revenue recognition.
    
 
   
(4) EBITDA is earnings before interest, taxes, depreciation and amortization, or
    operating income plus depreciation and amortization. EBITDA is presented
    because it is a widely accepted indicator of a company's ability to incur
    and service indebtedness. EBITDA, however, should not be considered as an
    alternative to net income as a measure of operating performance or an
    alternative to cash flow as a measure of liquidity. In addition, our
    definition of EBITDA may not be comparable to that reported by other
    companies.
    
 
                                       18
<PAGE>   22
 
           UNAUDITED CONSOLIDATED CONDENSED PRO FORMA FINANCIAL DATA
 
   
     The following unaudited consolidated condensed pro forma statement of
operations combines the historical statement of operations of us, Value Health,
Inc., Managed Prescription Network, Inc., together comprising the business known
as ValueRx, and DPS for the year ended December 31, 1998. On April 1, 1998, we
consummated the acquisition of ValueRx. Therefore, the financial information of
ValueRx is included in our consolidated statement of operations subsequent to
April 1, 1998. The unaudited consolidated condensed pro forma statement of
operations has been prepared to reflect the acquisitions of ValueRx and DPS and
the related financings, including this offering and the use of the net proceeds
from this offering, as if these events had occurred on January 1, 1998. Any cost
savings we may realize in connection with the integration of DPS are not
reflected in the pro forma presentation.
    
 
   
     The following unaudited consolidated condensed pro forma balance sheet
combines the historical consolidated balance sheet of us and DPS as of December
31, 1998. The unaudited consolidated condensed pro forma balance sheet has been
prepared to reflect the acquisition of DPS and the related financings, including
this offering and the use of the net proceeds from this offering, as if these
events had occurred on December 31, 1998.
    
 
     The detailed assumptions used to prepare the unaudited consolidated
condensed pro forma financial data are contained in the notes to the unaudited
consolidated condensed pro forma financial data. The unaudited consolidated
condensed pro forma financial data reflects the use of the purchase method of
accounting for the acquisitions of ValueRx and DPS. Under the purchase method of
accounting, the basis of accounting for the acquired assets and liabilities is
based upon their fair values at the date of acquisition.
 
   
     The pro forma adjustments represent our preliminary determination based
upon available information and assumptions which we consider reasonable under
the circumstances. The unaudited consolidated condensed pro forma data is not
necessarily indicative of our future results of operations or the results of
operations as they might have been had the acquisitions and the related
financings, including this offering and the use of the net proceeds from this
offering, been effective on the first day of the period presented. The unaudited
consolidated condensed pro forma financial data should be read in conjunction
with our separate historical consolidated financial statements and notes
included in this prospectus, the separate historical consolidated financial
statements and notes of ValueRx included in our Current Report on Form 8-K/A
dated June 12, 1998, the separate unaudited combined condensed financial
statements and notes for ValueRx for the three months ended March 31, 1998
included in this prospectus and the separate historical financial statements and
notes of DPS included in this prospectus.
    
 
   
     When reading the historical consolidated financial statements of us and
DPS, a notable difference exists with respect to the revenue recognition for
each of the companies. A substantial portion of our net revenues include
administrative fees, dispensing fees and the drug ingredient costs, as most
clients use one of our pharmacy networks. Where we only administer the contracts
between our clients and our clients' retail pharmacy networks, we record as net
revenues only the administrative fees we receives from our activities. DPS's net
revenues include its administrative fee from the activity of processing the
claim irrespective of a member utilizing a retail pharmacy included in one of
DPS's networks or its clients' network. The fundamental difference in the
revenue recognition is that DPS does not include the associated drug ingredient
costs in its net revenues as it does not have any liability to reimburse the
retail pharmacy included in its network unless DPS receives payment from its
client.
    
 
                                       19
<PAGE>   23
 
       UNAUDITED CONSOLIDATED CONDENSED PRO FORMA STATEMENT OF OPERATIONS
   
<TABLE>
<CAPTION>
                                              YEAR ENDED DECEMBER 31, 1998
                         ----------------------------------------------------------------------
                                                         VALUERX
                            EXPRESS                     PRO FORMA      VALUERX
                         SCRIPTS, INC.    VALUERX(1)   ADJUSTMENTS    PRO FORMA         DPS
                         -------------    ----------   -----------    ----------    -----------
                                    (IN THOUSANDS, EXCEPT SHARE AND PER SHARE DATA)
<S>                      <C>              <C>          <C>            <C>           <C>
Net revenues...........   $2,824,872       $409,928      $    --      $3,234,800    $   214,849(7)
Cost and expenses:
 Cost of revenues......    2,584,997(2)     375,295           --      2,960,292             548
 Selling, general and
   administrative......      148,990(2)      27,628       (3,606)(3)    173,012         234,477
 Corporate
   restructuring.......        1,651             --           --          1,651              --
 Write down of
   assets..............           --             --           --             --       1,092,184
                          ----------       --------      -------      ----------    -----------
                           2,735,638        402,923       (3,606)     3,134,955       1,327,209
                          ----------       --------      -------      ----------    -----------
Operating income
 (loss)................       89,234          7,005        3,606         99,845      (1,112,360)
Other income (net).....           --             --           --             --           1,308
Interest income........        7,236             56       (1,261)(4)      6,031              --
Interest expense.......      (20,230)            --       (7,007)(5)    (27,237)             --
                          ----------       --------      -------      ----------    -----------
Income (loss) before
 income taxes..........       76,240          7,061       (4,662)        78,639      (1,111,052)
Provision (benefit) for
 income taxes..........       33,566          3,665       (1,288)(6)     35,943        (388,825)
                          ----------       --------      -------      ----------    -----------
Net income (loss)......      $42,674         $3,396      $(3,374)     $  42,696     $  (722,227)
                          ==========       ========      =======      ==========    ===========
Basic earnings per
 share.................        $1.29
                          ==========
Diluted earnings per
 share.................        $1.27
                          ==========
Weighted average number
 of common shares
 outstanding during the
 period -- Basic.......       33,105
                          ==========
Weighted average number
 of common shares
 outstanding during the
 period -- Diluted.....       33,698
                          ==========
 
<CAPTION>
                                       YEAR ENDED DECEMBER 31, 1998
                         ---------------------------------------------------------
                             DPS            VALUERX      OFFERING
                          PRO FORMA         AND DPS      PRO FORMA     PRO FORMA
                         ADJUSTMENTS       PRO FORMA    ADJUSTMENTS   CONSOLIDATED
                         -----------       ----------   -----------   ------------
                              (IN THOUSANDS, EXCEPT SHARE AND PER SHARE DATA)
<S>                      <C>               <C>          <C>           <C>
Net revenues...........  $       --        $3,449,649     $    --      $3,449,649
Cost and expenses:
 Cost of revenues......          --        2,960,840           --       2,960,840(2)
 Selling, general and
   administrative......     (33,837)(8)      337,141           --         337,141(2)
                             (1,688)(9)
                            (34,823)(10)
 Corporate
   restructuring.......          --            1,651           --           1,651
 Write down of
   assets..............          --        1,092,184           --       1,092,184
                         -----------       ----------     -------      ----------
                            (70,348)       4,391,816           --       4,391,816
                         -----------       ----------     -------      ----------
Operating income
 (loss)................      70,348         (942,167)          --        (942,167)
Other income (net).....       1,924(11)        3,232           --           3,232
Interest income........      (2,164)(12)       3,867           --           3,867
Interest expense.......     (65,282)(13)     (92,519)      32,093(15)     (60,426)
                         -----------       ----------     -------      ----------
Income (loss) before
 income taxes..........       4,826        (1,027,587)     32,093        (995,494)
Provision (benefit) for
 income taxes..........      (1,683)(14)    (354,565)      12,837(16)    (341,728)
                         -----------       ----------     -------      ----------
Net income (loss)......      $6,509        $(673,022)     $19,256       $(653,766)(17)
                         ===========       ==========     =======      ==========
Basic earnings per
 share.................                                                   $(17.39)
                                                                       ==========
Diluted earnings per
 share.................                                                   $(17.12)
                                                                       ==========
Weighted average number
 of common shares
 outstanding during the
 period -- Basic.......                                     4,500(18)      37,605
                                                          =======      ==========
Weighted average number
 of common shares
 outstanding during the
 period -- Diluted.....                                     4,500(18)      38,198
                                                          =======      ==========
</TABLE>
    
 
- -------------------------
 
 (1) These historical amounts represent the unaudited statement of operations of
     ValueRx from January 1, 1998 through March 31, 1998.
 
   
 (2) Cost of revenues and selling, general and administrative expense include
     $7,559 and $18,874 of depreciation and amortization, respectively, for us
     in 1998. The pro forma consolidated cost of revenues and selling, general
     and administrative expense include $7,559 and $67,974 of depreciation and
     amortization, respectively.
    
 
   
 (3) Adjustment reflects the net decrease in depreciation and amortization of
     property and equipment and intangible assets, including goodwill resulting
     from our allocation of the ValueRx purchase price and conforming estimated
     useful lives. ValueRx depreciation and amortization expense of $8,811 has
     been eliminated and $5,205 has been added based on the fair value of
     property and equipment, goodwill, and other intangible assets. The fair
     value of property and equipment ($33,756) is being depreciated using the
    
 
                                       20
<PAGE>   24
 
   
straight-line method over 3 to 20 years. Goodwill ($289,863) and other
intangible assets, consisting of non-compete agreements ($9,130) and customer
contracts ($48,523), are being amortized using the straight-line method over 30
     years and 2 to 20 years, respectively.
    
 
   
 (4) Adjustment reflects the decrease in interest income resulting from our
     expending $100,908 of our short-term investments and cash equivalents to
     consummate the acquisition of ValueRx. The adjustment was calculated using
     the average interest rate (5.0%) earned by us on our investments during the
     quarter prior to the ValueRx acquisition.
    
 
 (5) Adjustment records the additional net interest expense and the amortization
     of the deferred financing fees during the first quarter of 1998 associated
     with the $440,000 credit facility utilized for the acquisition of ValueRx.
     The additional interest expense was determined assuming an average
     borrowing rate of 7.13% on the $360,000 borrowed under the $440,000 credit
     facility incurred to consummate the acquisition.
 
 (6) Adjustment reflects the amount required to result in a pro forma effective
     tax rate of 40%, inclusive of the impact of non-tax deductible goodwill and
     customer contract amortization.
 
   
 (7) Net revenues for DPS include revenues from SmithKline Beecham. Subsequent
     to our acquisition of DPS, revenues are anticipated to be consistent with
     historical revenues as DPS's existing contract with SmithKline Beecham
     remains in place.
    
 
   
 (8) Adjustment reflects the elimination of management fees paid to United
     HealthCare of $33,837, which under the DPS purchase agreement is to be
     reimbursed to us by SmithKline Beecham.
    
 
   
 (9) Adjustment also reflects the net decrease in the 1998 depreciation and
     amortization expense to $4,695 from $6,383 recorded by DPS resulting from
     the allocation of the purchase price to the assets acquired at their fair
     market value and to conform estimated and useful lives. Furniture,
     equipment and internal use software are being depreciated by us using the
     straight-line method over estimated useful lives of 5 to 8 years.
    
 
   
(10) Adjustment reflects the net decrease in the 1998 amortization expense for
     goodwill and other intangible assets. DPS's goodwill and other intangible
     assets amortization expense of $73,758 has been reversed, and our goodwill
     and other intangible assets, consisting of customer contracts, amortization
     of $38,935 has been included. Goodwill is being amortized using the
     straight-line method over the estimated useful life of 30 years. We have
     preliminarily assigned an estimated fair value to other intangible assets
     and are amortizing them using the straight-line method over the estimated
     useful lives of 1 to 20 years. We anticipate spending an estimated $10
     million to $20 million in non-recurring costs during the first twelve
     months subsequent to our acquisition of DPS relating to the integration of
     DPS's operations. These non-recurring costs have not been reflected in the
     unaudited consolidated condensed pro forma statement of operations.
    
 
   
(11) Adjustment reflects the elimination of DPS's $1,924 equity loss in its
     joint venture. SmithKline Beecham retained the equity interest in the joint
     venture.
    
 
   
(12) Adjustment reflects the decrease in interest income resulting from
     expending $48,081 of cash to consummate the acquisition of DPS. The
     adjustment was calculated using a current interest rate of 4.5% earned by
     us on our cash balances.
    
 
   
(13) Adjustment reflects the following:
    
 
   
      - the elimination of $26,413 in actual interest expense, exclusive of the
        impact of our hedge on variable rate interest incurred during fiscal
        1998 under our $440,000 credit facility, which has been replaced with
        the $1,050,000 credit facility
    
 
   
      - the addition of $87,832 in interest expense from borrowings of $890,000
        under the $1,050,000 credit facility and $150,000 under the senior
        subordinated bridge credit facility, assuming interest rates on the
        $1,050,000 credit facility of 7.67% for the revolving facility and the
        Term A facility and 8.42% for the
    
 
                                       21
<PAGE>   25
 
   
Term B facility, and an average rate of 10.72% on the senior subordinated bridge
credit facility, based on the actual rates incurred by us at consummation of the
$1,050,000 credit facility and $150,000 senior subordinated bridge facility. The
       interest rate on the senior subordinated bridge facility loan increases
       0.5% every quarter starting at 9.97% and increasing to 11.47%
    
 
   
      - the addition of $3,688 in deferred financing fees amortization and $175
        in annual administrative fees; these deferred financing fees are being
        amortized using the straight-line method over 6 to 8 years, which
        represents the maturity of the term loans under the $1,050,000 credit
        facility
    
 
   
(14) Adjustment reflects the tax effect of the pro forma adjustments. The tax
     effect for selling, general and administrative adjustments and other income
     (expense) adjustments has been determined using DPS's 1998 tax rate of 35%.
     The tax effect for interest income and interest expense have been
     determined using 40%. The goodwill and customer contracts amortization from
     the DPS acquisition is tax deductible due to our filing an Internal Revenue
     Code sec. 338(h)(10) election.
    
 
   
(15) Adjustment reflects the elimination of the interest expense impact from the
     retirement of the $150,000 senior subordinated bridge credit facility, at
     the interest rates in effect at consummation starting at 9.97% and
     increasing to 11.47%, and the retirement of $185,342 of the term loan
     borrowings under the $1,050,000 credit facility, at the actual interest
     rate at consummation of 8.42%, using the net proceeds of this offering, and
     the elimination of the deferred financing fees amortization expense
     associated with the retirement of term loan borrowings under our $1,050,000
     credit facility.
    
 
   
(16) Adjustment reflects the tax effect of the interest expense adjustment at a
     40% tax rate.
    
 
   
(17) The write-down of assets on DPS's books of $1,092,184 relates to the
     impairment of goodwill. If the acquisition of DPS had occurred on January
     1, 1998, goodwill on DPS's books would have been eliminated. Therefore, the
     impairment charge for goodwill would not have existed. Net income excluding
     this impairment charge would have been $56,154, or $1.49 per basic share
     and $1.47 per diluted share.
    
 
   
(18) Adjustment reflects the addition for a full year of the 4,500 shares of
     Class A common stock offered by this prospectus assuming an offering price
     of $78.375 per share.
    
 
                                       22
<PAGE>   26
 
            UNAUDITED CONSOLIDATED CONDENSED PRO FORMA BALANCE SHEET
 
   
<TABLE>
<CAPTION>
                                                                    ACQUISITION                    OFFERING
                                    EXPRESS SCRIPTS,                 PRO FORMA      ACQUISITION    PRO FORMA       PRO FORMA
                                          INC.            DPS       ADJUSTMENTS      PRO FORMA    ADJUSTMENTS     CONSOLIDATED
                                    ----------------   ----------   -----------     -----------   -----------     ------------
                                                         (IN THOUSANDS, EXCEPT SHARE AND PER SHARE DATA)
<S>                                 <C>                <C>          <C>             <C>           <C>             <C>
ASSETS:
Current assets:
  Cash............................       $122,589          $1,686     $(49,767)(1)     $74,508           $--          $74,508
  Accounts receivable.............        433,006          82,746       (5,338)(2)     510,414            --          510,414
  Intercompany receivable.........             --         371,827     (371,827)(2)          --            --               --
  Other current assets............        101,312           3,849       (1,880)(3)     103,281            --          103,281
                                       ----------      ----------   -----------     ----------     ---------       ----------
    Total current assets..........        656,907         460,108     (428,812)        688,203            --          688,203
Property and equipment, net.......         77,499          27,393           --         104,892            --          104,892
Goodwill, net.....................        282,163         546,040      179,232(4)    1,007,435            --        1,007,435
Deferred income taxes.............             --         430,374     (430,374)(3)          --            --               --
Other assets......................         78,892         293,580     (145,240)(5)     227,232        (3,243)(9)      223,989
                                       ----------      ----------   -----------     ----------     ---------       ----------
    Total assets..................     $1,095,461      $1,757,495    $(825,194)     $2,027,762       $(3,243)      $2,024,519
                                       ==========      ==========   ===========     ==========     =========       ==========
LIABILITIES AND STOCKHOLDERS' EQUITY:
Current liabilities:
  Current maturities of long-term
    debt..........................        $54,000            $ --     $(54,000)(6)        $ --          $ --             $ --
  Claims and rebates payable......        338,251         191,727           --         529,978            --          529,978
  Accounts payable and accrued
    expenses......................        147,045          53,154        9,492(7)      209,691        (1,297)(10)     208,394
                                       ----------      ----------   -----------     ----------     ---------       ----------
    Total current liabilities.....        539,296         244,881      (44,508)        739,669        (1,297)         738,372
Revolving debt....................             --              --      140,000(6)      140,000            --          140,000
Long-term debt....................        306,000              --      444,000(6)      750,000      (185,342)(11)     564,658
Senior subordinated bridge credit
  facility........................             --              --      150,000(6)      150,000      (150,000)(11)          --
Other long-term liabilities.......            471              --           --             471            --              471
                                       ----------      ----------   -----------     ----------     ---------       ----------
    Total liabilities.............        845,767         244,881      689,492       1,780,140      (336,639)       1,443,501
Stockholders' equity..............        249,694       1,512,614   (1,514,686)(8)     247,622       333,396(11)      581,018
                                       ----------      ----------   -----------     ----------     ---------       ----------
    Total liabilities and
      stockholders' equity........     $1,095,461      $1,757,495    $(825,194)     $2,027,762       $(3,243)      $2,024,519
                                       ==========      ==========   ===========     ==========     =========       ==========
</TABLE>
    
 
- -------------------------
 
   
 (1) Adjustment reflects the elimination of DPS cash which was retained by
     SmithKline Beecham and the use of $48,081 of our cash balances to fund the
     purchase of DPS.
    
 
   
 (2) Adjustment reflects the elimination of DPS assets retained by SmithKline
     Beecham.
    
 
   
 (3) Adjustment reflects the elimination of the historical deferred tax assets
     of DPS. As part of its acquisition, we will file an Internal Revenue Code
     sec. 338(h)(10) election. Accordingly, at December 31, 1998, the tax basis
     balance sheet and the book basis balance sheet are estimated to be the
     same, and therefore no deferred taxes are recognized with respect to DPS.
    
 
                                       23
<PAGE>   27
 
   
 (4) Adjustment reflects the excess of the purchase price of DPS over fair
     market value of the identified assets acquired. The purchase price of $700
     million, plus $25 million in transaction costs, plus the assumption and
     incurrence of liabilities totalling $258,835 was allocated in the following
     manner:
    
 
   
<TABLE>
<S>                                                           <C>
Current assets..............................................  $ 79,377
Property and equipment......................................    27,393
Deferred financing fees.....................................    19,483
Customer contracts..........................................   132,310
Goodwill....................................................   725,272
Current liabilities.........................................   258,835
</TABLE>
    
 
   
 (5) Adjustment reflects the following:
    
 
   
     - elimination of the DPS investment in the Diversified Prescription
       Delivery, L.L.C. joint venture of $6,610, which is being retained by
       SmithKline Beecham
    
 
   
     - elimination of a note receivable due from DPD in the amount of $512
    
 
   
     - elimination of the unamortized deferred financing fees in the amount of
       $3,453 related to the extinguishment of our $440,000 credit facility
    
 
   
     - elimination of other intangible assets of DPS in the amount of $286,458
    
 
   
     These eliminations were offset by $19,483 paid in deferred financing fees
     related to the $1,050,000 credit facility used to finance the DPS
     acquisition and the preliminary allocation of fair value to customer
     contracts in the amount of $132,310. We are in the process of establishing
     fair values for all identifiable assets and will adjust the fair value
     allocated to customer contracts accordingly when complete.
    
 
   
 (6) Adjustment reflects borrowings of $890,000 under our $1,050,000 credit
     facility and $150,000 under the senior subordinated bridge credit facility
     to finance the acquisition of DPS and which refinanced our existing
     outstanding debt of $360,000 under our $440,000 credit facility. The
     $1,050,000 credit facility consists of a $300,000 revolving credit
     facility, of which $140,000 has been borrowed, and a $750,000 term
     facility.
    
 
   
 (7) Adjustment reflects the elimination of a payable to DPD from DPS in the
     amount of $2,046, the reduction of taxes payable by $1,381 for the
     write-off of deferred financing fees, and the payment of accrued interest
     of $5,063 associated with the repayment of the $440,000 credit facility.
     These amounts were offset by accruals of $17,982 for transaction costs and
     other liabilities associated with the purchase of DPS.
    
 
   
 (8) Adjustment reflects the elimination of the DPS pre-acquisition equity
     balances and the write-off of our unamortized deferred financing fees of
     $2,072, net of tax, from our $440,000 credit facility as an extraordinary
     item. After the write-off of the unamortized deferred financing fees, net
     income after extraordinary items, excluding the write-down of assets
     impairment charge, would have been $54,082, or $1.44 per basic share and
     $1.42 per diluted share.
    
 
   
 (9) Adjustment reflects the elimination of our unamortized deferred financing
     fees related to the extinguishment of $185,342 borrowed under the
     $1,050,000 credit facility and the $150,000 senior subordinated bridge
     credit facility.
    
 
   
(10) Adjustment reflects the reduction in taxes payable as a result of the
     write-off of deferred financing fees related to the extinguishment of
     $185,342 borrowed under our $1,050,000 credit facility.
    
 
   
(11) Adjustment reflects the net proceeds received from our sale of 4,500 shares
     of Class A common stock offered pursuant to this prospectus at an assumed
     offering price of $78.375 per share. The proceeds from this offering will
     be used to repay the $150,000 senior subordinated bridge credit facility
     and $185,342 of the term loans under the $1,050,000 credit facility. The
     proceeds are offset by the write-off of $1,946, net of tax, of the deferred
     financing fees from the $1,050,000 credit facility as an extraordinary
     item. After the write-off of $1,946 and $2,072, see (8) above, in
     unamortized deferred financing fees, net income after extraordinary items,
     excluding the write-down of assets impairment charge, would have been
     $52,136, or $1.39 per basic share and $1.36 per diluted share.
    
 
                                       24
<PAGE>   28
 
               MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
                      CONDITION AND RESULTS OF OPERATIONS
 
OVERVIEW
 
   
     During 1998, we continued executing our growth strategy of generating sales
to new clients, expanding the services provided to existing clients, developing
new products and services for sale to existing clients and pharmaceutical
manufacturers and selectively pursuing strategic acquisitions and alliances. On
April 1, 1998, we consummated our first major acquisition by acquiring ValueRx,
the PBM operations of Columbia/HCA Healthcare, for approximately $460 million in
cash, which includes transaction costs and executive management severance costs
of approximately $6.7 million and $8.3 million, respectively. Specifically, we
acquired various subsidiaries of Columbia each now or formerly conducting
business as a PBM, including ValueRx Pharmacy Program. The acquisition is being
accounted for under the purchase method of accounting. Consequently, our
operating results include those of ValueRx from April 1, 1998. The net assets
acquired have been preliminarily recorded at their estimated fair value,
resulting in $289,863,000 of goodwill which is being amortized over 30 years.
    
 
   
     The acquisition of ValueRx enabled us to increase membership to
approximately 22.9 million lives as of December 31, 1998 from approximately 12.6
million lives as of December 31, 1997, representing an 81.7% increase. In 1997,
we increased membership by approximately 2.7 million lives from 9.9 million
lives as of December 31, 1996, representing a 27.3% increase. The increase in
membership in 1997 was primarily due to internal growth. Reflecting the addition
of new clients at January 1, 1999, our net membership increased approximately
600,000 to approximately 23.5 million lives. Although membership counts are
based on eligibility data, they necessarily involve some estimates,
extrapolations and approximations. For example, some plan designs allow for
family coverage under one identification number, and we make assumptions about
the average number of persons per family in calculating our total membership.
Because these assumptions may vary between PBMs, membership counts may not be
comparable between us and our competitors. However, we believe our membership
count provides a reasonable estimation of the population we serve, and can be
used as one measure of our growth.
    
 
   
     We primarily derive our revenues from the sale of PBM services in the
United States and Canada. Our PBM net revenues generally include administrative
fees, dispensing fees and ingredient costs of pharmaceuticals dispensed from
retail pharmacies included in one of our networks or from one of our mail
pharmacies. We then record the associated costs in cost of revenues. Where we
only administer the contracts between our clients and the clients' retail
pharmacy networks, we record as net revenues only the administrative fees we
receive from our activities. We also derive PBM net revenues from the sale of
informed decision counseling services through our Express Health LineSM division
and the sale of medical information management services, which include provider
profiling, formulary management support services and outcomes assessments,
through our Practice Patterns Science subsidiary. Non-PBM net revenues are
derived from:
    
 
   
     - the sale of pharmaceuticals for and the provision of infusion therapy
       services through our IVTx subsidiary
    
 
   
     - administrative fees received for members using our vision program through
       our alliance with Cole Managed Vision, a subsidiary of Cole National
       Corporation
    
 
                                       25
<PAGE>   29
 
   
     - administrative fees received from drug manufacturers for the dispensing
       of pharmaceuticals through our specialty distribution division
    
 
RESULTS OF OPERATIONS
 
NET REVENUES.
 
<TABLE>
<CAPTION>
                                                                                % INCREASE
                                           YEAR ENDED DECEMBER 31,         ---------------------
                                      ----------------------------------     1997        1998
                                        1996        1997         1998      OVER 1996   OVER 1997
                                      --------   ----------   ----------   ---------   ---------
                                                (IN THOUSANDS)
<S>                                   <C>        <C>          <C>          <C>         <C>
PBM.................................  $743,077   $1,191,173   $2,765,111     60.3%       132.1%
Non-PBM.............................    30,538       39,461       59,761     29.2%        51.4%
                                      --------   ----------   ----------     ----        -----
Net revenues........................  $773,615   $1,230,634   $2,824,872     59.1%       129.5%
                                      ========   ==========   ==========     ====        =====
</TABLE>
 
   
     We experienced significant growth in our net revenues during 1998 over 1997
primarily due to the acquisition of ValueRx and, to a lesser extent, our
continuing ability to attract new clients as well as additional members from
existing clients. Net revenues for the network pharmacy claims services
increased $1,175,659,000 or 141.7% in 1998 over 1997, and increased $311,195,000
or 60.0% in 1997 over 1996. These increases are the result of growth in the
number of network pharmacy claims processed of 54.7% in 1998 over 1997 and of
26.5% in 1997 over 1996, and an increase in the average net revenue per network
pharmacy claim of 56.3% in 1998 over 1997 and an increase of 26.6% in 1997 over
1996. The increase in average net revenue per network pharmacy claim for both
periods is primarily due to the following factors:
    
 
   
     - a larger number of clients using retail pharmacy networks established by
       us rather than retail pharmacy networks established by our clients, which
       results in our recording dispensing fees and ingredient costs in net
       revenues and cost of revenues, respectively
    
 
   
     - higher drug ingredient costs resulting from price increases for existing
       drugs, new drugs introduced into the marketplace and changes in
       therapeutic mix and dosage; these increases were partially offset by
       lower pricing offered by us in response to continued competitive
       pressures
    
 
   
     The number of clients using retail pharmacy networks established by us
increased significantly beginning in the second quarter of 1998 due to the
acquisition of ValueRx, as substantially all ValueRx clients used the retail
pharmacy networks established by ValueRx. As a result of this shift, gross
margin percentages are reduced but the dollar amount of the gross profit is not
significantly affected.
    
 
   
     Net revenues for mail pharmacy services increased $385,149,000 or 109.6% in
1998 over 1997, and $129,273,000 or 58.2% in 1997 over 1996. These increases are
the result of the growth in mail pharmacy claims processed of 90.5% in 1998 over
1997 and 40.8% in 1997 over 1996, and an increase in the average net revenue per
mail pharmacy claim of 10.0% in 1998 over 1997 and 12.4% in 1997 over 1996. The
increase in the average net revenue per mail pharmacy claim for both periods is
primarily due to the following factors:
 
     - the termination of inventory replacement programs maintained for two
       large clients during 1997
    
 
   
     - higher drug ingredient costs
    
 
                                       26
<PAGE>   30
 
   
These increases were partially offset by lower pricing offered by us in response
to continued competitive pressures.
    
 
   
     Under the inventory replacement programs offered in 1996 and the first four
months of 1997, the client provided drug inventory on consignment to fill mail
service prescriptions for members of the client's plan, and we included only our
dispensing fee as net revenue. For 1998 and most of 1997, all mail pharmacy
clients utilized our standard program in which we purchase and take title to the
inventory used to fill the prescriptions and, therefore, we include the
ingredient costs as well as the dispensing fees in net revenues. This change had
the effect of increasing both net revenues and cost of revenues during 1998 and
1997 compared to 1997 and 1996, respectively, but it had no significant effect
on our reported gross margin during 1998 and 1997 from the conversion to the
standard program. In addition, our inventory levels increased substantially
during 1997 over 1996 as a result of the termination of the inventory
replacement program.
    
 
   
     Net revenues for our non-PBM services increased 51.4% in 1998 over 1997 and
29.2% in 1997 over 1996. The increases are primarily attributable to the
continued growth in the number of our members and/or clients who receive these
services, higher drug ingredient costs and our ability to develop new products
and services.
    
 
COST AND EXPENSES.
 
<TABLE>
<CAPTION>
                                                                   % OF NET REVENUES
                                                                   ------------------
                                          YEAR ENDED                   YEAR ENDED            % INCREASE
                                         DECEMBER 31,                 DECEMBER 31,      ---------------------
                              ----------------------------------   ------------------     1997        1998
                                1996        1997         1998      1996   1997   1998   OVER 1996   OVER 1997
                              --------   ----------   ----------   ----   ----   ----   ---------   ---------
                                        (IN THOUSANDS)
<S>                           <C>        <C>          <C>          <C>    <C>    <C>    <C>         <C>
  PBM(1)....................  $661,946   $1,088,225   $2,540,360   89.1%  91.4%  91.9%    64.4%       133.4%
  Non-PBM(2)................    22,936       30,942       44,637   75.1%  78.4%  74.7%    34.9%        44.3%
                              --------   ----------   ----------   ----   ----   ----     ----        -----
Cost of revenues(3).........   684,882    1,119,167    2,584,997   88.5%  90.9%  91.5%    63.4%       131.0%
Selling, general and
  administrative............    46,267       57,257      130,116   6.0%   4.7%   4.6%     23.8%       127.2%
Depreciation and
  amortization(3)...........     2,836        5,360       18,874   0.4%   0.4%   0.7%     89.0%       252.1%
Corporate restructuring.....        --           --        1,651   0.0%   0.0%   0.0%       NM           NM
                              --------   ----------   ----------   ----   ----   ----     ----        -----
Total cost and expenses.....  $733,985   $1,181,784   $2,735,638   94.9%  96.0%  96.8%    61.0%       131.5%
                              ========   ==========   ==========   ====   ====   ====     ====        =====
</TABLE>
 
- -------------------------
 
(1)  % of net revenues data is percentage against PBM net revenues.
 
(2)  % of net revenues data is percentage against non-PBM net revenues.
 
   
(3)  Represents depreciation and amortization expense included in selling,
     general and administrative expenses on our statement of operations. Cost of
     revenues includes depreciation and amortization expense on property and
     equipment.
    
 
NM = not meaningful.
 
   
     Our cost of revenues for PBM services as a percentage of PBM net revenues
continued to increase in 1998 and 1997 over 1997 and 1996, respectively. Cost of
revenues for our pharmacy network claims and mail pharmacy claims increased
145.5% and 106.7% during 1998, and 65.7% and 60.2% during 1997, respectively.
The PBM gross margin as a percentage of PBM net revenues declined 0.5% during
1998 over 1997 and 2.3% during 1997 over 1996. The decrease in gross margin
percentage in 1997 is due to the shift toward pharmacy networks established by
us, as opposed to those established by our clients, higher drug ingredient costs
and the termination of the inventory replacement programs, as
    
 
                                       27
<PAGE>   31
 
   
discussed in "-- Net revenues." The decrease in gross margin percentage in 1998
is primarily due to the shift towards pharmacy networks established by us. The
pharmacy network shift continued due to the acquisition of ValueRx, as the
ValueRx clients primarily used retail pharmacy networks established by ValueRx.
This decrease was partially offset by operating efficiencies achieved in our
mail pharmacies during 1998 and revenues generated from integrated PBM services,
such as medical and drug data analysis, that provide higher gross margins.
    
 
   
     Cost of revenues for non-PBM services decreased as a percentage of non-PBM
net revenues from 1997 primarily due to our development of new business that
generated higher gross margins of $11,039,000. These higher gross margins were
partially offset by increasing costs of $2,320,000 associated with continued
expansion of our operations and continued change of approximately $3,040,000 in
the product mix sold in 1998 compared to 1997. Cost of revenues for non-PBM
services increased as a percentage of non-PBM net revenues in 1997 over 1996
primarily due to increasing costs associated with continued expansion of our
operations.
    
 
   
     Selling, general and administrative expenses increased $72,859,000 or
127.2% in 1998 over 1997, and $10,990,000 or 23.8% in 1997 over 1996. The
increase during 1998 was the result of our acquisition of ValueRx, costs
incurred during the integration of ValueRx and costs required to expand the
operational and administrative support functions to enhance management of the
pharmacy benefit. The increase during 1997 was primarily due to the expansion of
the operational and administrative support functions to enhance management of
the pharmacy benefit. As a percentage of net revenues, selling, general and
administrative expenses for 1998 decreased slightly to 4.6% from 4.7% in 1997.
In 1997, selling, general and administrative expenses, as a percentage of net
revenues, decreased 1.3% from 6.0% in 1996. Selling, general and administrative
expenses, as a percentage of net revenues, in both periods were affected by our
recording of higher net revenues due to the shift towards pharmacy networks
established by us, as opposed to those established by our clients, and the
termination of the inventory replacement programs, as discussed in "-- Net
revenues."
    
 
   
     As part of our overall plan to achieve operating economies, we have been
integrating ValueRx into our historical business. During 1998, we substantially
met our integration goals by combining existing contracts and contracting
procedures related to both suppliers and providers, integrating financial
reporting systems, reducing the ValueRx computer systems from five to three,
consolidating financial operations, consolidating organizational structure and
employee benefits and implementing a new sales and marketing program for
enhanced PBM services. We expect to reduce the ValueRx computer systems to one
by October 1999. Except for some new systems development costs, we are expensing
integration costs as incurred. As of December 31, 1998, we have capitalized
$5,209,000 in new systems development costs and we have expensed $8,331,000 in
incremental integration costs.
    
 
   
     Depreciation and amortization substantially increased during 1998 over 1997
due to the acquisition of ValueRx. During 1998, we recorded amortization expense
for goodwill and other intangible assets of $12,183,000. The remaining increases
in 1998 and 1997 are primarily due to our expansion of our operations and
enhancement of our information systems to better manage the pharmacy benefit.
    
 
   
     On June 17, 1998, we announced that we had reached an agreement with Cole
pursuant to which Cole will provide vision care services for our clients and
their members. The agreement enables us to focus on our PBM business while still
offering vision care
    
 
                                       28
<PAGE>   32
 
   
services to our members by transferring functions performed by our subsidiary
Express Scripts Vision Corporation to Cole, effective September 1, 1998. In
conjunction with the agreement, we also announced plans to close the operations
of our wholly owned subsidiary PhyNet, a vision program management service
organization that is part of our non-PBM services segment. As a result, we
recorded a one-time restructuring charge of $1,651,000 in 1998 comprised of
asset write-downs to their net realizable value, less cost of disposal, of
$1,235,000 and expected employee transition cash payments of $416,000 for 61
employees. During 1998, we incurred cash payments of $184,000 for employee
transition and non-cash adjustments of $704,000 for the write-down of assets. We
anticipate completing the remainder of the restructuring transactions by the end
of the third quarter of 1999.
    
 
INTEREST INCOME (EXPENSE), NET.
 
<TABLE>
<CAPTION>
                                                       % OF NET REVENUES
                                                      -------------------
                                 YEAR ENDED               YEAR ENDED             % INCREASE
                                DECEMBER 31,             DECEMBER 31,       ---------------------
                         --------------------------   -------------------     1997        1998
                          1996     1997      1998     1996   1997   1998    OVER 1996   OVER 1997
                         ------   ------   --------   ----   ----   -----   ---------   ---------
                               (IN THOUSANDS)
<S>                      <C>      <C>      <C>        <C>    <C>    <C>     <C>         <C>
Interest expense.......  $  (59)  $ (225)  $(20,230)   NM     NM     (0.7)%     NM           NM
Interest income........   3,509    6,081      7,236   0.5%   0.5%    0.2%     73.3%        19.0%
                         ------   ------   --------    --     --    -----     ----       ------
Interest income
  (expense), net.......  $3,450   $5,856   $(12,994)  0.5%   0.5%    (0.5)%   69.7%          NM
                         ======   ======   ========    ==     ==    =====     ====       ======
</TABLE>
 
- -------------------------
 
NM = not meaningful.
 
   
     During 1998, we recorded significant interest expense resulting from the
financing of the ValueRx acquisition with $360 million in borrowings; see
"-- Liquidity and Capital Resources". Interest income increased $1,155,000 or
19.0% in 1998 over 1997, and $2,572,000 or 73.3% in 1997 over 1996. The
increases in 1998 and 1997 are due to our investment of larger cash balances. In
addition, in 1997 the larger cash balances were invested at higher interest
rates than those in 1996.
    
 
PROVISION FOR INCOME TAXES.
 
   
<TABLE>
<CAPTION>
                                                                                        EFFECTIVE TAX RATE
                                                                                       --------------------
                                     YEAR ENDED                    % INCREASE               YEAR ENDED
                                    DECEMBER 31,             ----------------------        DECEMBER 31,
                            -----------------------------      1997         1998       --------------------
                             1996       1997       1998      OVER 1996    OVER 1997    1996    1997    1998
                            -------    -------    -------    ---------    ---------    ----    ----    ----
                                   (IN THOUSANDS)
<S>                         <C>        <C>        <C>        <C>          <C>          <C>     <C>     <C>
Provision for income
  taxes...................  $16,932    $21,277    $33,566      25.7%        57.8%      39.3%   38.9%   44.0%
</TABLE>
    
 
   
     Our effective tax rate increased in 1998 over 1997 due to the
non-deductible goodwill and customer contract amortization expense resulting
from the ValueRx acquisition. We expect that our effective tax rate will
gradually decline toward the statutory rate as our operating growth continues.
    
 
                                       29
<PAGE>   33
 
NET INCOME AND EARNINGS PER SHARE.
 
<TABLE>
<CAPTION>
                                                               % OF NET REVENUES
                                                               ------------------
                                         YEAR ENDED                YEAR ENDED            % INCREASE
                                        DECEMBER 31,              DECEMBER 31,      ---------------------
                                 ---------------------------   ------------------     1997        1998
                                  1996      1997      1998     1996   1997   1998   OVER 1996   OVER 1997
                                 -------   -------   -------   ----   ----   ----   ---------   ---------
                                       (IN THOUSANDS)
<S>                              <C>       <C>       <C>       <C>    <C>    <C>    <C>         <C>
Net income....................   $26,148   $33,429   $42,674   3.4%   2.7%   1.5%     27.8%       27.7%
Basic earnings per share......     $0.81     $1.02     $1.29                           25.9%      26.5%
Diluted earnings per share....     $0.80     $1.01     $1.27                           26.3%      25.7%
Weighted average shares
  outstanding -- Basic........    32,160    32,713    33,105                           1.7%        1.2%
Weighted average shares
  outstanding -- Diluted......    32,700    33,122    33,698                           1.3%        1.7%
</TABLE>
 
   
     Our net income increased $9,245,000 or 27.7% in 1998 over 1997, and
$7,281,000 or 27.8% in 1997 over 1996. Excluding the after-tax one-time
corporate restructuring charge for the managed vision business of $1,002,000,
basic earnings per share and diluted earnings per share for 1998 would have been
$1.32 and $1.30, respectively.
    
 
   
     On October 12, 1998, we announced a two-for-one stock split of our Class A
and Class B common stock for stockholders of record on October 20, 1998,
effective October 30, 1998. The split was effected in the form of a dividend by
issuance of one additional share of Class A common stock for each share of Class
A common stock outstanding and one additional share of Class B common stock for
each share of Class B common stock outstanding. The earnings per share and the
weighted average number of shares outstanding for basic and diluted earnings per
share for each period have been adjusted for the stock split.
    
 
LIQUIDITY AND CAPITAL RESOURCES
 
<TABLE>
<CAPTION>
                                                                                       % INCREASE
                                                     YEAR ENDED DECEMBER 31,      ---------------------
                                                   ----------------------------     1997        1998
                                                    1996      1997       1998     OVER 1996   OVER 1997
                                                   -------   -------   --------   ---------   ---------
                                                          (IN THOUSANDS)
<S>                                                <C>       <C>       <C>        <C>         <C>
Net cash provided by operations..................  $29,863   $52,503   $126,574     75.8%       141.1%
</TABLE>
 
   
     The increase in operating cash flow generated by us in 1998 is primarily
due to the increase in net income and our continued focus on improving working
capital management. The increase in operating cash flow generated in 1997 is
primarily due to the increase in net income and commencement of our working
capital management focus. The operating cash flow generated in 1996 is primarily
due to the increase in net income. Management expects to fund our future debt
service, integration costs, year 2000 costs, internet business development costs
and other normal operating cash needs primarily with operating cash flow or with
working capital borrowings under our $1.05 billion credit facility.
    
 
   
     Our capital expenditures in 1998 increased $10,836,000 or 83.2% over 1997
primarily due to our concerted effort to invest in information technology to
enhance the services provided to our clients. In addition, we invested in
equipment to improve efficiency at our mail pharmacy facilities and to manage
the growth encountered at these facilities. In 1997, capital expenditures
increased $3,537,000 or 37.3% primarily due to the investments required for the
management of our growth. Management expects to continue investing in technology
that will provide efficiencies in operations, manage growth and enhance the
services provided to our clients. Management expects to fund future anticipated
capital
    
 
                                       30
<PAGE>   34
 
   
expenditures primarily with operating cash flow or with working capital
borrowings under the $1.05 billion credit facility.
    
 
   
     During the first quarter of 1999, we negotiated a $1.05 billion credit
facility with a bank syndicate led by Credit Suisse First Boston and Bankers
Trust Company consisting of $750 million in term loans, including $285 million
of Term A loans and $465 million of Term B loans, and a $300 million revolving
credit facility. The agreement became effective on April 1, 1999. The Term A
loans and the revolving credit facility will mature on March 31, 2005 and the
Term B loans will mature on March 31, 2007. Approximately $940 million in
borrowings from this new facility were used to consummate the DPS acquisition,
refinance our $440 million credit facility, of which $360 million was
outstanding, and other indebtedness and pay related fees and expenses. The
credit facility is secured by the capital stock of each of our existing and
subsequently acquired domestic subsidiaries, excluding Practice Patterns
Science, Great Plains Reinsurance, ValueRx of Michigan, Diversified NY IPA and
Diversified Pharmaceutical Services (Puerto Rico), and 65% of the stock of our
foreign subsidiaries.
    
 
   
     The credit facility requires us to pay interest quarterly on an interest
rate spread based on several LIBOR or base rate options. Using a LIBOR spread,
the Term A loans and the revolving loan require a spread of 2.75%, resulting in
an interest rate, including the spread, at May 1, 1999, of 7.625%. The Term B
loans require a LIBOR spread of 3.5%, resulting in an interest rate, including
the spread, at May 1, 1999, of 8.375%. Beginning in March 2001, we are required
to make annual principal payments on the Term A loans of $42,750,000 in 2001,
$57,000,000 in 2002 and 2003, $62,700,000 in 2004 and $65,550,000 in 2005. The
Term B loans require annual principal payments of $4,650,000 beginning in March
2000 until 2005, $111,600,000 in 2006 and $325,500,000 in 2007. The credit
facility also contains customary financial covenants including a minimum
interest coverage ratio, a maximum ratio of total debt to EBITDA and a minimum
fixed charge coverage ratio. In addition, we are required to pay an annual fee
of 0.5%, payable in quarterly installments, on the unused portion of the
revolving loan. At March 31, 1999 and December 31, 1998, we were in compliance
with all covenants associated with the $440 million credit facility. As a result
of refinancing our $440 million credit facility, we will write-off the remaining
deferred financing fees at March 31, 1999 of $3,250,000, $1,950,000 net of tax,
as an extraordinary item during the second quarter of 1999.
    
 
   
     To alleviate interest rate volatility, we entered into an interest rate
swap arrangement for a notional principal amount of $360 million, effective
April 3, 1998, with the First National Bank of Chicago, a subsidiary of Bank One
Corporation. Under the terms of the swap, we agreed to receive a floating rate
of interest on the amount of the term loan facility based on a three-month LIBOR
rate in exchange for payment of a fixed rate of interest of 5.88% per annum. The
notional amount of the swap amortizes in conjunction with the principal balance
of the term loan. As a result, we had, in effect, converted our variable rate
term debt to fixed rate debt at 5.88% for the entire term of the term loan plus
the credit rate spread. Under the new $1.05 billion credit facility, we will be
maintaining the interest rate swap to hedge the future variable interest rate
payments on $360 million of our $1.05 billion credit facility. The swap will, in
effect, convert $360 million of the $1.05 billion credit facility from variable
rate debt to fixed rate debt at 5.88% plus the credit rate spread attributable
to the new facility.
    
 
   
     In order to assist our funding of the DPS acquisition, we obtained a $150
million senior subordinated bridge credit facility from Credit Suisse First
Boston Corporation and Bankers Trust Company. The facility became effective on
April 1, 1999 and matures on
    
 
                                       31
<PAGE>   35
 
   
March 31, 2000 unless converted into a term loan. The facility requires us to
make quarterly interest payments on a spread over several LIBOR or base rate
options. The facility requires us to pay an initial spread of 5%, resulting in
an interest rate, including the spread, at May 1, 1999, of 9.97%, and increasing
0.5% every quarter. The proceeds from this offering will be used to repay the
$150 million senior subordinated bridge credit facility and $185 million of the
Term B loans under the $1.05 billion credit facility. As a result of the partial
repayment of the Term B loans, we will write-off approximately $3,243,000,
$1,946,000 net of tax, of the Term B deferred financing fees as an extraordinary
item.
    
 
   
     As of December 31, 1998, we had repurchased a total of 475,000 shares of
our Class A common stock under the open-market stock repurchase program
announced by us on October 25, 1996, although no repurchases occurred during
1998. Our board of directors approved the repurchase of up to 1,700,000 shares
and placed no limit on the duration of the program. Future purchases, if any,
will be in the amounts and at the times as we deem appropriate based upon
prevailing market and business conditions, subject to restrictions contained in
our $1.05 billion credit facility.
    
 
   
     We have reviewed and intend to continue to review potential acquisitions
and affiliation opportunities. We believe that available cash resources, bank
financing or the issuance of additional common stock could be used to finance
any acquisitions or affiliations. However, there can be no assurance we will
make other acquisitions or affiliations in 1999 or thereafter.
    
 
OTHER MATTERS
 
   
     On March 16, 1998, we announced that, in connection with the consummation
of the sale by New York Life Insurance Company of NYLCare Health Plans to Aetna
U.S. Healthcare (which occurred on July 15, 1998), we reached an agreement with
Aetna to extend our PBM services and infusion therapy services agreements to HMO
members through December 31, 2003. The existing PBM contract pricing is
effective through December 31, 1999, and thereafter pricing adjustments, which
we believe reflect an appropriate market price, will be instituted for the year
2000 and subsequent periods. Our agreement with Aetna provides that we will
continue providing PBM services, excluding informed decision counseling
services, to 1.4 million HMO members through 2003, which is comparable to the
NYLCare HMO membership base served by us prior to the Aetna acquisition. The
infusion therapy agreements are extended under their current terms until
December 31, 2000, and thereafter limited price adjustments may take effect
under circumstances. The existing agreements for managed vision care and
informed decision counseling will continue until December 31, 1999. We expect to
continue providing PBM services to members of the NYLCare indemnity programs
until the members are converted to new health insurance policies, which is
anticipated to occur primarily during 1999. In connection with the Aetna
arrangement, we have reached an agreement whereby New York Life may make up to
$2.8 million of transition-related payments to us in 1999, depending upon the
level of profit we derive from the provision of selected PBM services to Aetna,
compared to an estimate of the profit that would have been derived had the
NYLCare/Aetna transaction not taken place, using certain agreed upon assumptions
about profit margins, membership levels and drug utilization rates. The overall
impact of this arrangement on earnings per share is not expected to be material
in 1999.
    
 
                                       32
<PAGE>   36
 
   
     During 1998 and 1997, 4.8% and 15.7%, respectively, of our PBM net revenues
were from services provided to members of HMOs owned or managed by NYLCare or
insurance policies administered by NYLCare while it was a wholly owned
subsidiary of New York Life. Of our net revenues for non-PBM services, 21.5% and
54.8% in 1998 and 1997, respectively, were for services provided to members of
HMOs owned or managed by NYLCare or insurance policies administered by NYLCare
while it was a wholly owned subsidiary of New York Life.
    
 
   
     Effective with the first quarter of 1998, we adopted Statement of Financial
Accounting Standards Statement 130, Reporting Comprehensive Income. FAS 130
requires noncash changes in stockholders' equity to be combined with net income
and reported in a new financial statement category entitled comprehensive
income. Other than net income, the only component of comprehensive income for us
is the change in the foreign currency translation account.
    
 
   
     Effective with fiscal year end 1998, we adopted Statement of Financial
Accounting Standards Statement 131, Disclosures About Segments of an Enterprise
and Related Information. FAS 131 requires that we report selected information if
specific requirements are met about our operating segments, including
information about services, geographic areas of operation and major customers.
The information is to be derived from the management approach, which designates
the internal organization that is used by management for making operating
decisions and assessing performance as the source of our operating segments.
Adoption of FAS 131 did not affect our results of operations or our financial
position but did affect the disclosure of segment information; see Note 13 in
our 1998 consolidated financial statements.
    
 
   
     In June 1998, Statement of Financial Accounting Standards Statement 133,
Accounting for Derivative Instruments and Hedging Activities, was issued. FAS
133 requires all derivatives to be recognized as either assets or liabilities in
the statement of financial position and measured at fair value. In addition, FAS
133 specifies the accounting for changes in the fair value of a derivative based
on the intended use of the derivative and the resulting designation. FAS 133 is
effective for all fiscal quarters of fiscal years beginning after June 15, 1999,
and will be applicable to our first quarter of fiscal year 2000. Our present
interest rate swap, see "-- Liquidity and Capital Resources", would be
considered a cash flow hedge. Accordingly, the change in the fair value of the
swap would be reported on the balance sheet as an asset or liability. The
corresponding unrealized gain or loss representing the effective portion of the
hedge will be initially recognized in stockholders' equity and other
comprehensive income and subsequently any changes in unrealized gain or loss
from the initial measurement date will be recognized in earnings concurrent with
the interest expense on our underlying variable rate debt. If we had adopted FAS
133 as of December 31, 1998, we would record the unrealized loss of $7,209,000
as a liability and reduction in stockholders' equity and other comprehensive
income.
    
 
POST YEAR-END EVENTS
 
   
     On April 1, 1999, we acquired DPS for $700 million in cash. We financed the
acquisition with $48 million of our cash, $890 million in borrowings from our
$1.05 billion credit facility and $150 million from our senior subordinated
bridge credit facility; see "-- Liquidity and Capital Resources". The
acquisition will be accounted for under the purchase method of accounting. Under
our agreement with SmithKline Beecham relating to our acquisition of DPS,
SmithKline Beecham is obligated to dissolve a joint venture
    
 
                                       33
<PAGE>   37
 
   
relationship in a company known as Diversified Prescription Delivery, which
provides mail pharmacy services, including services for some clients of DPS.
SmithKline Beecham has executed a letter of intent to acquire the 50% interest
in DPD that it does not currently own. Following the acquisition of this 50%
interest, SmithKline Beecham will transfer ownership of DPD to us or to another
company that we control. We will not pay SmithKline Beecham any additional
amounts beyond what we have already paid to acquire DPS. Consummation of this
transaction is subject to conditions, including preparation of formal contract
documents and the approval of regulatory authorities.
    
 
   
     On March 29, 1999, we announced our plans to launch two Internet sites,
YourPharmacy.com and DrugDigest.org. YourPharmacy.com will serve as an online
drug store and offer both prescription and over-the-counter medications,
vitamins, herbs and health and beauty aids. DrugDigest.org will provide
fact-based information on a variety of medications, vitamins and herbs. Both
sites are expected to be operational during the second quarter of 1999. By
allowing us to communicate more effectively and efficiently with our existing
members, we should be able to reduce our operating costs by utilizing on-line
communication as opposed to more expensive call center operations and paper-
based correspondence. To date we have funded the development of the Internet
sites through operating cash flows and have expensed these amounts as incurred.
We expect to continue funding the development and operation of these sites with
operating cash flows or with working capital borrowings under our $1.05 billion
credit facility.
    
 
   
     On February 1, 1999, we announced a three-and-a-half-year contract to
provide PBM services to Blue Cross and Blue Shield of Massachusetts. Beginning
in the second half of 1999, we will provide retail network and mail pharmacy
services, claims processing, clinical management support and other related
services to approximately 1.2 million members.
    
 
YEAR 2000
 
   
     Our operations rely heavily on computers and other information systems
technologies. In 1995, we began addressing the "year 2000" issue, which refers
to the inability of computer systems to properly recognize calendar dates beyond
December 31, 1999. This arises as a result of systems having been programmed
with two digits rather than four digits to define the applicable year in order
to conserve computer storage space, reduce the complexity of calculations and
produce better performance. The two-digit system may cause computers to
interpret the year "00" as "1900" rather than as "2000", which may cause system
failures or produce incorrect results when dealing with date-sensitive
information beyond 1999.
    
 
   
     We formed a year 2000 task force to address this issue, which has performed
a self-assessment and developed a compliance plan that addresses:
    
 
   
     - internally developed application software
    
 
   
     - vendor developed application software
    
 
   
     - operating system software
    
 
   
     - utility software
    
 
   
     - vendor/trading partner-supplied files
    
 
   
     - externally provided data or transactions
    
 
   
     - non-information technology devices that are material to our business
    
 
   
     - adherence to applicable industry standards
    
 
                                       34
<PAGE>   38
 
   
Our plan covers both the traditional Express Scripts and ValueRx systems.
Progress in each area is monitored and management reports are given
periodically.
    
 
   
     We have various applications and operating systems that are considered
critical to our operations. Approximately 75% of these systems have been tested
by us in an integrated environment for year 2000 compliance. The remaining
systems will either be tested and, if necessary, modified to be compliant by the
end of the second quarter of 1999, or information residing on these systems will
be integrated into a year 2000 compliant operating system. Testing of the
applications and operating systems includes the adjudication process, the
eligibility process, the billing and remittance process, the communication
process and the reporting process, including financial reporting. In addition,
since 1995, all new internally developed software has been developed to be year
2000 compliant and will be tested during the remainder of 1999.
    
 
   
     We have sent out approximately 1,500 letters to critical vendor/trading
partners requesting a status report regarding their year 2000 compliance. We
have received responses for approximately 30% of the letters sent, with the
majority of the vendor/trading partners responding that they are currently
addressing the year 2000 issue and expect to be compliant. We are formulating a
list of vendor/trading partners that have not responded in order to send second
requests. In addition, we are participating in a joint effort with other PBMs,
retail pharmacy chains, transaction routing companies and adjudication software
vendors to test year 2000 compliance in the industry. The joint effort is called
the "Y2K Provider & Vendor Testing Coalition" and is being facilitated by The
National Health Information Network. The coalition has the support of major U.S.
retail pharmacies, including American Stores, CVS, Eckerd, Rite-Aid, Wal-Mart
and Walgreens. The inclusion of transaction routing vendors and software
companies could permit up to 95% of our pharmacy network to be tested. The
program will allocate the retail pharmacy chains and software vendors among the
various PBMs who will be required to test the vendors' and pharmacy chains' year
2000 compliance. The testing is expected to be completed during the third
quarter of 1999.
    
 
   
     We have also contacted several hundred clients and several thousand
pharmacies whose computer systems appear to us not to be year 2000 compliant in
an effort to increase awareness of the problem and minimize or eliminate any
disruption in data transfer activity between any of these parties and us. We
have developed date windowing logic, which forces an entry into the century
field of a computer application if one is not provided by the user, which we
believe will address many issues concerning retail pharmacies and clients with
noncompliant systems. Due to our contracts typically extending over several
years and our receipt of member eligibility information from clients that
reflect dates beyond 2000, we have been receiving information that would
identify year 2000 issues for several years. Any problems we have encountered to
date have been rectified using our windowing logic. There can be no assurance,
however, that all of these problems that may be encountered in the future can be
rectified with the windowing logic.
    
 
   
     In addressing the year 2000 issue, we will incur internal staff costs as
well as external consulting and other expenses related to infrastructure
enhancements necessary to prepare our systems for the new century. Since 1995,
we have incurred approximately $3,500,000 addressing the year 2000 issue. We
anticipate spending an additional $750,000 to $1,000,000 during 1999. All
expenditures are being expensed as incurred. To date, these costs have not had a
material adverse effect on our results of operations or financial
    
 
                                       35
<PAGE>   39
 
   
condition, and are not expected to have a material adverse effect on our future
results of operations or financial condition.
    
 
   
     We believe that, with appropriate modifications to existing computer
systems, updates by vendors and trading partners and conversion to new software
in the ordinary course of our business, the year 2000 issue will not pose
significant operational problems for us. However, if the above-described
conversions are not completed in a proper and timely manner by all affected
parties, or if our logic for communicating with noncompliant systems is
ineffective, the year 2000 issue could result in material adverse operational
and financial consequences to us. There can be no assurance that our efforts, or
those of our vendors and trading partners, who are beyond our control, will be
successful in addressing the year 2000 issue.
    
 
   
     We are in the process of formalizing our contingency plans to address
potential risks, including risks of vendor/trading partner noncompliance, as
well as noncompliance of any of our material operations, and are expected to be
substantially complete by the end of the second quarter of 1999. However, the
formalization of the contingency plans is an ongoing process as we complete our
testing and receive updates from vendor/trading partners. In addition, there can
be no assurance that our contingency plans will successfully address all
potential circumstances or consequences.
    
 
IMPACT OF INFLATION
 
   
     Changes in prices charged by manufacturers and wholesalers for
pharmaceuticals affect our net revenues and cost of revenues. To date we have
been able to recover price increases from our clients under the terms of our
agreements. As a result, changes in pharmaceutical prices have not had a
significant adverse affect on us.
    
 
MARKET RISK
 
   
     We are exposed to market risk from changes in interest rates. As part of
our overall risk management policy, we have entered into an interest rate swap,
see "-- Liquidity and Capital Resources", in order to manage exposure to
interest rate risk. We do not enter into swap agreements for trading purposes.
Interest rate risk is monitored on the basis of changes in fair value, and a
sensitivity analysis is used to determine the impact interest rate risk will
have on the fair value of the interest rate swap, measuring the change in the
net present value arising from changes in interest rates. A 10% decline in
interest rates at December 31, 1998, would increase the unrealized loss of our
interest rate swap by $3,812,000.
    
 
                                       36
<PAGE>   40
 
                                    BUSINESS
 
INDUSTRY OVERVIEW
 
   
     Prescription drug costs are the fastest growing component of health care
costs in the United States. The U.S. Health Care Financing Administration
estimates that pharmaceuticals currently account for approximately 6.5% of U.S.
health care expenditures, and are expected to increase to 8% by 2007. Estimated
U.S. pharmaceutical sales for 1998 were approximately $75 billion, and HCFA
projects continued sales increases at an average annual growth rate of
approximately 10% through 2007, compared to an average annual growth rate of
approximately 7% for total health care costs during this period. Factors
underlying this trend include:
    
 
   
     - increases in research and development expenditures by drug manufacturers,
       resulting in many new drug introductions
    
 
   
     - a shorter U.S. Food and Drug Administration approval cycle for new
       pharmaceuticals
    
 
   
     - high prices for new "blockbuster" drugs
    
 
   
     - an aging population
    
 
   
     - increased demand for prescription drugs due to increased disease
       awareness by patients, effective direct-to-consumer advertising by drug
       manufacturers and a growing reliance on medication in lieu of lifestyle
       changes
    
 
     Health benefit providers have been seeking ways to better understand and
control drug costs. PBMs help health benefit providers to provide a
cost-effective drug benefit and to better understand the impact of prescription
drug utilization on total health care expenditures. PBMs coordinate the
distribution of outpatient pharmaceuticals through a combination of
benefit-management services, including retail drug card programs, mail pharmacy
services and formulary management programs.
 
     PBMs emerged during the late 1980s by combining traditional pharmacy claims
processing and mail pharmacy services to create an integrated product offering
that could help manage the prescription drug benefit for payors. During the
early 1990s, numerous PBMs were created, with some providers offering a
comprehensive, integrated package of services.
 
     The services offered by the more sophisticated PBMs have broadened to
include disease management programs, compliance programs, outcomes research,
drug therapy management programs and sophisticated data analysis. These advanced
capabilities require resources that may not be available to all PBMs, so further
industry consolidation may occur. If prescription drug costs continue to
escalate and become an even larger portion of overall health care expenditures,
more advanced capabilities will be needed to manage these costs so that health
benefit providers will be able to continue to offer a quality prescription drug
benefit to their members. The more sophisticated PBMs should be in the best
position to offer these services.
 
THE COMPANY
 
     We are the largest full-service PBM company independent of pharmaceutical
manufacturer or drug store ownership in North America. PBMs coordinate the
distribution of outpatient pharmaceuticals through a combination of benefit
management services,
 
                                       37
<PAGE>   41
 
   
including retail drug card programs, mail pharmacy services, drug formulary
management programs and other clinical management programs. We provide these
types of services for clients that include HMOs, health insurers, third-party
administrators, employers and union-sponsored benefit plans. We believe our
independence from pharmaceutical manufacturer ownership allows us to make
unbiased formulary recommendations to our clients, balancing both clinical
efficacy and cost. We also believe our independence from drug store ownership
allows us to construct a variety of convenient and cost-effective retail
pharmacy networks for our clients, without favoring any particular pharmacy
chain.
    
 
   
     We are the third largest PBM in North America in terms of total members,
and we have one of the largest managed care membership bases of any PBM. Before
1998, our growth was driven almost exclusively by our ability to expand our
product offerings and increase our client and membership base through internally
generated growth. From 1992 through 1997, our net revenues and net income
increased at compound annual growth rates of 58% and 49%, respectively. While
our internal growth strategy remains a major focus, we have recently
complemented our internal growth strategy with two substantial acquisitions.
These acquisitions add to the scale of our membership base and broaden our
product offerings. In April 1998, we acquired ValueRx, the PBM business of
Columbia/ HCA Healthcare, and in April 1999, we acquired DPS, the PBM business
of SmithKline Beecham. On a pro forma basis including this offering, our net
revenues and net income for 1998 would have been approximately $3.4 billion and
$57.1 million, respectively, excluding a $709.9 million after-tax write-down of
assets charge and a $1.0 million after-tax restructuring charge.
    
 
   
     As of January 1, 1999, our PBM services were provided to approximately 23.5
million members in the United States and Canada who were enrolled in health
plans sponsored by our clients. As of the same date, after giving effect to the
DPS acquisition, we would have served approximately 47.0 million members,
including 10.5 million members under DPS's contract with United HealthCare which
will terminate without renewal on May 31, 2000. Although membership counts are
based on eligibility data, they necessarily involve some estimates,
extrapolations and approximations. For example, some plan designs allow for
family coverage under one identification number, and we make assumptions about
the average number of persons per family in calculating our total membership.
These assumptions vary between us and DPS, and probably vary between us and our
competitors as well. Consequently, membership counts may not be comparable
between us and our competitors. However, we believe our membership count
provides a reasonable estimation of the population we serve, and can be used as
one measure of our growth. Besides United Healthcare, some of our other large
clients include Aetna U.S. Healthcare, Oxford Health Plans and the State of New
York Empire Plan Prescription Drug Program.
    
 
   
     Our PBM services are primarily delivered through networks of retail
pharmacies that are under non-exclusive contract with us and through five mail
pharmacy service centers that we own and operate. Our largest retail pharmacy
network includes more than 52,000 retail pharmacies, representing more than 99%
of all retail pharmacies in the United States. In 1998, including ValueRx and
DPS on a pro forma basis, we processed approximately 284 million pharmacy claims
with estimated total drug spending of approximately $10 billion.
    
 
     Our PBM services include:
 
     - network claims processing, mail pharmacy services, benefit design
       consultation, drug utilization review, formulary management programs,
       disease management and
 
                                       38
<PAGE>   42
 
medical and drug data analysis services, and compliance and therapy management
programs for our clients
 
   
     - market research programs for pharmaceutical manufacturers
    
 
     - medical information management services, which include provider profiling
       and outcome assessments, through our majority owned subsidiary Practice
       Patterns Science
 
     - informed decision counseling services through our Express Health Line(SM)
       division
 
     Our non-PBM services include:
 
     - infusion therapy services through our wholly owned subsidiary IVTx
 
   
     - distribution of pharmaceuticals requiring special handling or packaging
       through our specialty distribution division
    
 
                                    STRATEGY
 
     Our strategy is to increase our membership base and grow profitably by
focusing on generating sales to new clients and expanding the services we
provide to existing clients, developing new products and services for sale to
existing clients and drug manufacturers and selectively pursuing acquisitions
and alliances to increase our membership base and enhance our product offerings.
 
   
     - Generation of Sales to New Clients and Growth from Existing Clients.  Our
       predominant growth strategy is to pursue sales to new clients and
       generate growth in the membership base of existing clients. Our compound
       annual growth rate in members, excluding our recent acquisitions, is 48%
       since our initial public offering in 1992. The managed care market
       segment has experienced, and we believe will continue to experience,
       solid growth. We believe additional opportunities also exist in the
       employer and union market segments. Recent large new clients under
       contract with us include Blue Cross and Blue Shield of Massachusetts and
       Buyer's Health Care Action Group. Growth within the membership base of
       existing clients is also important to our strategy. When our clients,
       such as managed care organizations, third-party administrators and other
       third-party payors, market their service offerings to potential members,
       they generally market our prescription drug program as part of their
       offerings. As their client base grows, our membership base typically also
       grows. Our recently announced internet pharmacy service initiative,
       YourPhamacy.com and DrugDigest.org, will assist us in executing this
       strategy. By allowing us to communicate more effectively and efficiently
       with our existing members, we believe that we will be able to reduce our
       operating costs by utilizing on-line communication as opposed to more
       expensive call center operations and paper-based correspondence. We also
       plan to increase the utilization of our existing mail pharmacies, which
       processed over 7.4 million prescriptions in 1998 to distribute
       prescription medications ordered through our Internet e-commerce site. In
       addition, we believe that sales of both pharmaceutical and
       non-pharmaceutical products to the non-member general public will help us
       attract new clients. Furthermore, based on our clinical capabilities,
       information databasing and established expertise in managing prescription
       drug usage, we believe DrugDigest.org will be a comprehensive and
       credible source of information on prescription and non-prescription
       medications.
    
 
                                       39
<PAGE>   43
 
   
     - Development and Sale of New Products and Services to Existing Clients and
       Drug Manufacturers.  We continue to emphasize the development and sale of
       new products and services as part of our PBM offerings to our existing
       clients, and we have begun marketing our products to selected
       pharmaceutical manufacturers. We believe these products and services are
       necessary to compete effectively in the current business environment and
       to differentiate us from our competitors on a measure other than price.
       We intend to continue to invest in these capabilities in the future.
       Products and services developed by us in recent years include disease
       management programs, advanced formulary compliance programs, drug
       outcomes research, drug therapy management programs, medical information
       management, proprietary clinical services and sophisticated management
       reporting capabilities. We believe a particular growth area in the PBM
       industry will be medical information management. We believe our majority
       owned subsidiary Practice Patterns Science is an industry leader in this
       area, having developed proprietary software to process and sort medical
       claims, prescription drug claims and clinical laboratory data for use by
       managed care organizations and other health care companies. Through our
       internet initiative we will also sell over-the-counter medications,
       health and beauty aids, vitamins and herbs to our existing clients. The
       clients most interested in these advanced capabilities are managed care
       organizations, but we believe third-party administrators and large
       employers present opportunities for the sale of these advanced
       capabilities as well. We also intend to continue to expand our product
       and service offerings to pharmaceutical manufacturers. Recent
       developments in our business include the implementation of compliance,
       therapy management and market research programs. We intend to continue to
       invest in capabilities that will strengthen our relationships with
       manufacturers.
    
 
   
     - Growth Through Strategic Acquisitions and Alliances.  During the past
       several years we have begun to supplement our strong internal growth with
       selected acquisitions of other PBMs and strategic alliances. Our
       objectives in pursuing acquisitions and alliances are to increase the
       scale of our business, expand our client base, increase our penetration
       of PBM markets and expand our product and service offerings. Our
       acquisitions of ValueRx and DPS substantially increased our membership
       base, diversified our client base and increased our presence in key
       market segments and enhanced our clinical capabilities, systems and
       technologies. Our acquisition of ValueRx added approximately 10.0 million
       members and our acquisition of DPS added approximately 23.5 million
       members. We have formulated and are implementing a detailed plan to
       integrate ValueRx and DPS into our operations and have formulated a
       similar plan for integrating DPS. We are also party to strategic
       alliances with Premier Purchasing Partners and The Manufacturers Life
       Insurance Company. We intend to continue to seek alliances with other
       organizations and to selectively identify potential acquisition targets
       in the future.
    
 
PRODUCTS AND SERVICES
 
PHARMACY BENEFIT MANAGEMENT SERVICES
 
     OVERVIEW.  Our PBM services involve the management of outpatient
prescription drug usage to foster high quality, cost-effective pharmaceutical
care through the application of
 
                                       40
<PAGE>   44
 
   
managed care principles and advanced information technologies. We offer our PBM
services to our clients in the United States and Canada. Our PBM services
include:
    
 
   
     - retail pharmacy network administration
    
 
   
     - mail pharmacy services
    
 
   
     - benefit plan design consultation
    
 
   
     - formulary administration
    
 
   
     - electronic point-of-sale claims processing
    
 
   
     - drug utilization review
    
 
   
     - the development of advanced formulary compliance and therapeutic
       intervention programs
    
 
   
     - therapy management services such as prior authorization, therapy
       guidelines, step therapy protocols and formulary management interventions
    
 
   
     - sophisticated management information reporting and analytic services
    
 
   
     - provider profiling and outcomes assessments
    
 
   
     - informed decision counseling
    
 
     During 1998, 97.9% of our net revenues were derived from PBM services,
compared to 96.8% and 96.1% during 1997 and 1996, respectively. The number of
retail pharmacy network claims processed and mail pharmacy claims processed has
increased to 113.2 million and 7.4 million claims, respectively, in 1998, from
26.3 million and 1.6 million claims, respectively, in 1994. During 1997 and
1996, we processed 73.2 million and 57.8 million retail pharmacy network claims,
respectively, and 3.9 million and 2.8 million mail pharmacy claims,
respectively.
 
     RETAIL PHARMACY NETWORK ADMINISTRATION.  We contract with retail pharmacies
to provide prescription drugs to members of the pharmacy benefit plans managed
by us. In the United States, these pharmacies typically discount the price at
which they will provide drugs to members in return for designation as a network
pharmacy. We manage four nationwide networks in the United States and one
nationwide network in Canada that are responsive to client preferences related
to cost containment and convenience of access for members. We also manage
networks of pharmacies that are under direct contract with our managed care
clients or networks that we have designed to meet the specific needs of some of
our larger clients.
 
     All retail pharmacies in our pharmacy networks communicate with us on-line
and in real time to process prescription drug claims. When a member of a plan
presents his or her identification card at a network pharmacy, the network
pharmacist sends the specified claim data in an industry-standard format through
our systems, which process the claim and respond to the pharmacy, typically
within one or two seconds. The electronic processing of the claim involves:
 
   
     - confirming the member's eligibility for benefits under the applicable
       health benefit plan and the conditions to or limitations of coverage,
       such as the amount of copayments or deductibles the member must pay
    
 
   
     - performing a concurrent drug utilization review analysis and alerting the
       pharmacist to possible drug interactions or other indications of
       inappropriate prescription drug usage
    
 
                                       41
<PAGE>   45
 
   
     - updating the member's prescription drug claim record
    
 
   
     - if the claim is accepted, confirming to the pharmacy that it will receive
       payment for the drug dispensed
    
 
     MAIL PHARMACY SERVICES.  We integrate our retail pharmacy services with our
mail pharmacy services. We operate five mail pharmacies, located in Maryland
Heights, Missouri; Tempe, Arizona; Albuquerque, New Mexico; Bensalem,
Pennsylvania; and Troy, New York. These pharmacies provide members with
convenient access to maintenance medications and enable us and our clients to
control drug costs through operating efficiencies and economies of scale. In
addition, through our mail service pharmacies, we are directly involved with the
prescriber and member, and are generally able to achieve a higher level of
generic substitutions and therapeutic interventions than can be achieved through
the retail pharmacy networks. This further reduces our clients' costs.
 
     BENEFIT PLAN DESIGN AND CONSULTATION SERVICES.  We offer consultation and
financial modeling services to assist the client in selecting a benefit plan
design that meets its needs for member satisfaction and cost control. The most
common benefit design options we offer to our clients are:
 
   
     - financial incentives and limitations on the drugs covered by the plan,
       including drug formularies, flat dollar or percentage of prescription
       cost copayments, deductibles or annual benefit maximum
    
 
   
     - generic drug substitution incentives
    
 
   
     - incentives or requirements to use only network pharmacies or to order
       particular drugs only by mail
    
 
   
     - limitations on the number of days' supply of a drug that can be obtained
    
 
The selected benefit design is entered into our electronic claims processing
system, which applies the plan design parameters as claims are submitted and
enables us and our clients to monitor the financial performance of the plan.
 
     ADVANCED FORMULARY COMPLIANCE AND THERAPY MANAGEMENT SERVICES.  We provide
advanced formulary compliance services to our clients. Formularies are lists of
drugs for which coverage is provided under the applicable plan. They are widely
used in managed health care plans and, increasingly, by other health plan
managers. We administer a number of different formularies for our clients that
often identify preferred drugs whose use is encouraged or required through
various benefit design features. Historically, many clients have selected a plan
design which includes an open formulary in which all drugs are covered by the
plan and preferred drugs, if any, are merely recommended. More advanced options
consist of restricted formularies, in which various financial or other
incentives exist for the selection of preferred drugs over their non-preferred
counterparts, or closed formularies, in which benefits are available only for
drugs listed on the formulary. Formulary preferences can be encouraged:
 
   
     - by restricting the formulary through plan design features, such as tiered
       copayments, which require the member to pay a higher amount for a
       non-preferred drug
    
 
   
     - through prescriber education programs, in which we or the managed care
       client actively seek to educate the prescribers about the formulary
       preferences
    
 
   
     - through our OptiMed(SM) drug therapy management program, which actively
       promotes therapeutic and generic interchanges to reduce drug costs
    
 
                                       42
<PAGE>   46
 
   
We also offer the ExpressTherapeutics(SM) program, an innovative proprietary
drug utilization review and clinical intervention program, to assist clients in
managing compliance with the prescribed drug therapy and inappropriate
prescribing practices.
    
 
     Our National Pharmacy and Therapeutics Committee, composed of independent
physicians and pharmacists, evaluates drugs within a therapy class to determine
whether it is clinically appropriate to give formulary preference to one drug
over another. If clinical appropriateness is established to the committee's
satisfaction, it then evaluates the cost-effectiveness of drugs in the therapy
class. Once a client adopts a formulary, we administer the formulary through our
electronic claims processing system, which alerts the pharmacist if the
prescriber has not prescribed the preferred drug. We or the pharmacist can then
contact the prescriber to attempt to obtain the prescriber's consent to switch
the prescription to the preferred product.
 
     INFORMATION REPORTING AND ANALYSIS AND DISEASE MANAGEMENT
PROGRAMS.  Through the development of increasingly sophisticated management
information and reporting systems, we manage prescription drug benefits more
effectively. We have developed various services to offer our clients. The first
service enables a client to analyze prescription drug data to identify cost
trends and budget for expected drug costs, to assess the financial impact of
plan design changes and to identify costly utilization patterns through an
on-line prescription drug decision support tool called RxWorkbench(TM). This
service permits our clients' medically sophisticated personnel, such as a
clinical pharmacist employed by an HMO, to analyze prescription drug data
on-line.
 
   
     In addition, our majority owned subsidiary Practice Patterns Science offers
provider profiling, disease management support services and outcomes
assessments, and has developed proprietary software to process and sort medical
claims, prescription drug claims and clinical laboratory data. This data is then
used to produce comprehensive information about treatment of patients that can
be used by managed care organizations and other companies involved in formulary
management programs to treat a particular disease in a quality, cost-effective
manner. The patient-specific data generated through all of these services can
then be compared to data in PPS's normative databases, and PPS can determine the
effectiveness of treatment and calculate the total costs of that treatment,
including the prescription drug component, resulting in an assessment of the
particular outcome for a given patient. The information can also be used to
analyze the practice patterns of health care providers and create a provider
profile, then develop empirically based "best practice" protocols, which
recommend treatment regimens for specific diseases.
    
 
   
     We offer additional disease management programs to assist health benefit
plans in managing the total health care costs associated with several diseases,
such as asthma, diabetes and cardiovascular disease. These disease management
programs are based upon the premise that patient and provider behavior can
positively influence medical outcomes and reduce overall medical costs. Patient
identification can be accomplished through claims data analysis or
self-enrollment, and risk stratification surveys are conducted to establish a
plan of care for individual program participants. Patient education is primarily
effected through a series of telephone and written communications with nurses
and pharmacists, and both providers and patients receive progress reports on a
regular basis. Outcome surveys are conducted and results are compiled to analyze
the clinical, personal and economic impact of the program.
    
 
     ELECTRONIC CLAIMS PROCESSING SYSTEM.  Our electronic claims processing
system enables us to implement sophisticated intervention programs to assist in
managing
 
                                       43
<PAGE>   47
 
prescription drug utilization. The system can be used to alert the pharmacist to
generic substitution and therapeutic intervention opportunities and formulary
compliance issues, or to administer prior authorization and step-therapy
protocol programs at the time a claim is submitted for processing. Our claims
processing system also creates a database of drug utilization information that
can be accessed both at the time the prescription is dispensed and also on a
retrospective basis to analyze utilization trends and prescribing patterns for
more intensive management of the drug benefit.
 
     INFORMED DECISION COUNSELING SERVICES.  We offer health care decision
counseling services through our Express Health Line(SM) division. This service
allows a member to call a toll-free telephone number and discuss a health care
matter with a care counselor who utilizes on-line decision support protocols and
other guidelines to provide information to assist the member in making an
informed decision in seeking appropriate treatment. Records of each call are
maintained on-line for future reference. The service is available 24 hours a
day. Multilingual capabilities and service for the hearing impaired are also
available. The counselors provide follow-up service to members to determine if
their situation was resolved or if the counselor may provide additional
assistance. Member satisfaction and outcomes assessments are tracked through a
combination of member surveys, a quality assurance plan and system reports.
 
   
     INTERNET PHARMACY SERVICES.  On March 29, 1999, we announced our plans to
launch two internet sites, YourPharmacy.com and DrugDigest.org. YourPharmacy.com
will serve as an online drug store, and offer both prescription and
over-the-counter medications, vitamins, herbs and health and beauty aids.
DrugDigest.org will provide fact-based information on a variety of medications,
vitamins and herbs. Both sites are expected to be operational during the second
quarter of 1999. Although both sites will be available to anyone, we expect to
capitalize on the use of the sites by our existing membership base.
    
 
NON-PBM SERVICES
 
   
     In addition to PBM services, we also provide non-PBM services including
outpatient infusion therapy, specialty distribution and vision care to our
clients. During 1998, 2.1% of our net revenues were derived from non-PBM
services, compared to 3.2% and 3.9% during 1997 and 1996, respectively.
    
 
   
     OUTPATIENT INFUSION THERAPY SERVICES.  We provide infusion therapy services
which involve the administration of prescription drugs and other products to a
patient by catheter, feeding tube or intravenously, through our wholly owned
subsidiary IVTx. IVTx's clients, which include managed care organizations,
third-party administrators, insurance companies, case management companies,
unions and self-insured employers, benefit from outpatient infusion therapy
services because the length of hospital stays can be reduced. Rather than
receiving infusion therapy in a hospital, IVTx provides infusion therapy
services to patients at home, in a physician's office or in a free-standing
center operated by a managed care organization or other entity. IVTx provides
antimicrobial, cardiovascular, hematologic, nutritional, analgesic,
chemotherapeutic, hydration, endocrine, respiratory and AIDS management
treatments to patients. IVTx generally prepares the treatments in one of its
infusion therapy pharmacies, which are licensed independently of our mail
pharmacies. The treatments are either administered under the supervision of
IVTx's staff of registered nurses or licensed vocational nurses who are employed
at one of the IVTx sites or, in areas where IVTx does not have a facility,
through contracted registered nurses employed or otherwise retained by nursing
agencies. IVTx may also contract with physicians to provide
    
 
                                       44
<PAGE>   48
 
consultation services to its sites and contract for pharmacy services for
patients who live in outlying areas.
 
     We have facilities supporting our infusion therapy operations in Houston,
Texas; Dallas, Texas; Columbia, Maryland; Maryland Heights, Missouri; Columbia,
Missouri; Northvale, New Jersey; Tempe, Arizona; and West Chester, Pennsylvania.
IVTx's information system maintains patient profiles and documents doses and
supplies dispensed, and its drug utilization review component accesses our
prescription records for members receiving both infusion and oral drug therapies
to screen for drug interactions, incompatibilities and allergies.
 
     SPECIALTY DISTRIBUTION SERVICES.  We began offering specialty distribution
services during the fourth quarter of 1997 through our Tempe, Arizona facility.
This service assists pharmaceutical manufacturers with the distribution of, and
creation of a database of information for, products requiring special
handling/packaging or products targeted to a specific physician or patient
population.
 
     VISION CARE SERVICES.  Until September 1998, we offered a managed vision
care program through a network of approximately 9,000 vision care providers
consisting primarily of optometrists and a smaller number of ophthalmologists.
In addition to administering the network, we ground and edged lenses, assembled
eyeglasses and distributed eyeglasses and contact lenses from our vision lab
formerly located in Earth City, Missouri.
 
   
     We entered into an agreement, effective September 1, 1998, with Cole
Managed Vision, a subsidiary of Cole National Corporation, pursuant to which
Cole provides vision care services for our clients and their members. The
agreement enables us to focus on our PBM business while still offering a vision
care service to our members by transferring functions performed by our Express
Scripts Vision Corporation to Cole. The Cole vision program is offered to
substantially all of our PBM clients, and we receive a fee from Cole based on
usage of the vision benefit by members. In conjunction with the Cole agreement,
we also announced plans to close the operations of our wholly owned subsidiary,
PhyNet, a vision program management service organization.
    
 
SUPPLIERS
 
     We maintain an extensive inventory in our mail pharmacies of brand name and
generic pharmaceuticals. If a drug is not in our inventory, we can generally
obtain it from a supplier within one or two business days. We purchase our
pharmaceuticals either directly from manufacturers or through wholesalers.
During 1998, approximately 56.2% of our pharmaceutical purchases were through
one wholesaler, most of which were brand name pharmaceuticals. Generic
pharmaceuticals are generally purchased directly from manufacturers. We believe
that alternative sources of supply for most generic and brand name
pharmaceuticals are readily available.
 
CLIENTS
 
   
     We are a major provider of PBM services to the managed care industry,
including several large HMOs, and the employer industry, both directly and
through third-party administrators. Excluding United HealthCare, some of our
largest managed care clients include Aetna U.S. Healthcare and Oxford Health
Plans. The Aetna plans we service are composed primarily of the plans of the
former NYLCare Health Plans entity, which was a wholly owned subsidiary of New
York Life Insurance Company. Some of our largest employer groups include the
State of New York Empire Plan Prescription Drug Program,
    
                                       45
<PAGE>   49
 
   
through a subcontracting relationship with CIGNA HealthCare, and the State of
Ohio Bureau of Workers' Compensation Fund. We also market our PBM services
through preferred provider organizations, group purchasing organizations, health
insurers, third-party administrators of health plans and union-sponsored benefit
plans.
    
 
   
     We provide PBM services, including informed decision counseling, and
non-PBM services, including infusion therapy services, to HMOs owned or managed
by Aetna/NYLCare, and provide PBM services to insurance plans underwritten and
administered by Aetna/NYLCare. Of our net revenues from PBM services in 1998,
4.8% was for services provided to members of HMOs owned or managed by NYLCare or
insurance policies administered by NYLCare while NYLCare was a subsidiary of New
York Life. In connection with Aetna's purchase of NYLCare, an agreement has been
reached to extend our PBM service agreements with HMOs, excluding the informed
decision counseling component, and our infusion therapy agreements through
December 31, 2003, with new pricing to take effect after December 31, 1999. We
also expect to continue to provide PBM services to members of the NYLCare
indemnity programs until their members are converted to Aetna policies, which is
anticipated to occur during 1999.
    
 
   
     With the completion of the DPS acquisition, United HealthCare became our
largest client, with approximately 10.5 million members. DPS's contract with
United HealthCare will expire on May 31, 2000, and United HealthCare has
indicated it will be moving to another provider at that time. In our financial
analysis of the DPS acquisition, we assumed United HealthCare would not renew
its contract. However, if we are not able to reduce our costs on a basis
commensurate with our expectations and manage the transition of this large
client to another provider both efficiently and effectively, the loss of this
contract may materially adversely affect our business and results of operations.
    
 
     In February 1999, we announced a three-and-a-half-year contract with Blue
Cross and Blue Shield of Massachusetts. Beginning in the second half of 1999, we
will provide PBM services, including retail network and mail pharmacy services,
claims processing, clinical management support and other related services to
approximately 1.2 million members.
 
   
     In January 1999, DPS announced a five-year contract with Oxford Health
Plans. Under the contract, we provide retail network, claims processing,
clinical management support and other related services to approximately 1.8
million members.
    
 
ACQUISITIONS AND STRATEGIC ALLIANCES
 
   
     In April 1999, we acquired DPS from SmithKline Beecham and one of its
affiliates for $700 million in cash. We financed the acquisition and refinanced
all of our existing indebtedness through a $1.05 billion credit facility and a
$150 million senior subordinated bridge credit facility. Goodwill and customer
contract amortization from the DPS acquisition is tax deductible. DPS
traditionally concentrated on the managed care segment of the PBM market and,
with the completion of this acquisition, we have one of the largest managed care
membership bases of any PBM. Although we continue to be the third largest PBM in
North America in terms of total members, the DPS acquisition significantly added
to the size of our membership base and will provide us with additional operating
scale. In addition, the acquisition provides us with enhanced clinical
capabilities, such as technologies for modeling the clinical and cost
effectiveness of therapy alternatives, and sophisticated information and
reporting systems.
    
 
                                       46
<PAGE>   50
 
   
     In April 1998, we acquired the PBM business known as ValueRx from Columbia/
HCA Healthcare for approximately $460 million in cash, including approximately
$15 million in transaction costs and executive severance costs. Historically,
while both we and ValueRx served all segments of the PBM market, we primarily
focused on managed care and smaller self-funded plan sponsors, and ValueRx
concentrated on health insurance carriers and large employer and union groups.
We believe the ValueRx acquisition has provided and will continue to provide us
with additional resources and expertise, which will allow us to better serve our
clients and competitively pursue new business in all segments of the PBM market.
    
 
   
     In January 1996, we entered into a series of agreements with American
HealthCare Systems Purchasing Partners, now known as Premier Purchasing
Partners, a health care group purchasing organization affiliated with APS
Healthcare, now known as Premier. Under our agreement with Premier, we are the
exclusive preferred vendor of PBM services recommended by Premier and the
Premier Partnership to health plans eligible to participate in the Premier
Partnership's group purchasing programs. In May 1996, we issued 454,546 shares
of our Class A common stock to the Premier Partnership as a result of the number
of Premier plan members that were receiving our PBM services and the outcome of
certain joint drug purchasing initiatives. The Premier Partnership could become
entitled to receive up to an additional 4,500,000 shares of our Class A common
stock, depending upon the number of members in Premier-affiliated managed care
plans that contract for our PBM services. A calculation is made on April 1 of
each year to determine if a stock issuance will be made. If the Premier
Partnership earns stock totaling over 5% of our total voting stock, it is
entitled to have its designee nominated for election to our board of directors.
As of the date of this prospectus, the Premier Partnership has not reached this
5% threshold. Premier designates us as its exclusive preferred PBM provider, but
an individual Premier member is not required to enter into an agreement with us.
    
 
   
     In November 1995, we entered into a ten-year strategic alliance with The
Manufacturers Life Insurance Company, one of the largest providers of group
health insurance policies in Canada, pursuant to which we are the exclusive
provider of PBM services. As a result of this alliance, Manulife can earn up to
approximately 474,000 shares of our Class A common stock, depending on its
achievement of pre-determined pharmacy claim volumes from 1996 to 2000. In
addition, if Manulife does not terminate the alliance in either year 6 or year
10 of the agreement, in each of these years it will receive a warrant to
purchase up to 237,000 shares of our Class A common stock exercisable at 85% of
the then fair market value of these shares. The actual number of shares will
depend upon claims volume in each year.
    
 
   
     In January 1995, we entered into an exclusive three-year agreement to
provide PBM services to Coventry Corporation, pursuant to which Coventry
received 50,000 shares of our Class A common stock. In December 1997, Coventry
extended its agreement for an additional two years. In connection with this
extension, we issued, as an advance discount, a seven-year warrant to purchase
an additional 50,000 shares of our Class A common stock, exercisable at a price
of $26.4544 per share; the share price is 90% of the per share market value at
the time of renewal.
    
 
COMPANY OPERATIONS
 
   
     GENERAL.  In our various facilities in the United States, we own and
operate five mail pharmacies and seven member service/pharmacy help desk call
centers, four of which are
    
 
                                       47
<PAGE>   51
 
   
now linked to create a virtual call center environment. Electronic pharmacy
claims processing for the traditional Express Scripts/ValueRx business is
principally directed through our Maryland Heights, Missouri facility then routed
to the appropriate computer platform at our Maryland Heights, Missouri or Tempe,
Arizona facility or at Perot Systems' facility, which maintains some of our
computer hardware. The claims processing for the traditional DPS business is
currently handled by Electronic Data Systems Corp., or EDS, at its facility in
Plano, Texas, with whom DPS had an agreement for these services. EDS owns the
computer hardware and operating software, and we own the application software
for these operations. At our Canadian facility, we have sales and marketing,
client services, pharmacy help desk, clinical, provider relations and management
information systems capabilities.
    
 
   
     SALES AND MARKETING; CLIENT SERVICE.  We market our PBM services in the
United States primarily through an internal staff of regional marketing
representatives and sales personnel located in various cities throughout the
United States. The marketing representatives are supported by a staff of client
service representatives. Our sales and marketing personnel and client service
representatives are organized by type of business served, for example managed
care group, employer group or union group. Marketing in Canada is conducted by
marketing representatives located in Mississauga, Ontario, who are assisted by
our personnel based in the United States. Although we cross-sell our infusion
therapy services to our PBM clients, our IVTx subsidiary employs its own sales
and marketing and client service personnel to take advantage of individual
market opportunities.
    
 
     MEMBER SERVICES.  We believe client satisfaction is dependent upon member
satisfaction. Members can call us toll-free, 24 hours a day, to obtain
information about their prescription drug plan. We employ member service
representatives who are trained to respond to member inquiries.
 
   
     PROVIDER RELATIONS.  Our provider relations group is responsible for
contracting and administering our pharmacy networks. To participate in our
retail pharmacy networks, pharmacists must meet specific qualifications and are
periodically required to represent to us that their applicable state licensing
requirements are being maintained and that they are in good standing. Pharmacies
can contact our various pharmacy help desks toll-free, 24 hours a day, for
information and assistance in filling prescriptions for members. In addition,
our provider relations group audits selected pharmacies in the retail pharmacy
networks to determine compliance with the terms of the contract with us or our
clients.
    
 
   
     CLINICAL SUPPORT.  Our Health Management Services Department employs
clinical pharmacists, data analysts and outcomes researchers who provide
technical support for our PBM services. These staff members assist in providing
high level clinical pharmacy services such as formulary development, drug
information programs, clinical interventions with physicians, development of
drug therapy guidelines and the evaluation of drugs for inclusion in clinically
sound therapeutic intervention programs. The Health Management Services
Department also analyzes and prepares reports on clinical pharmacy data for our
clients and conducts specific data analyses to evaluate the cost-effectiveness
of various drug therapies.
    
 
   
     MANAGEMENT INFORMATION SYSTEMS.  Our Information Systems Department
supports our pharmacy claims processing systems and other management information
systems which are essential to our operations. Uninterrupted point-of-sale
electronic retail pharmacy claims processing is a significant operational
requirement for us, and we are in the process of integrating the systems
acquired with the DPS and ValueRx acquisitions with our
    
 
                                       48
<PAGE>   52
 
   
historical systems located at our Maryland Heights, Missouri and Tempe, Arizona
facilities. Substantially all claims for the traditional Express Scripts/ValueRx
business are presently directed through our Maryland Heights, Missouri facility
then routed to the appropriate computer platform at our Maryland Heights,
Missouri or Tempe, Arizona facility, or at Perot Systems' facility. Perot
Systems maintains the computer hardware for the ValueRx systems at its facility
in Richardson, Texas. Our historical claims processing systems located in our
Maryland Heights, Missouri and Tempe, Arizona facilities are designed to be
redundant, which enables us to do substantially all claims processing in one
facility if the other facility is unable to process claims. Disaster recovery
services for the ValueRx systems are provided by a third party. The claims
processing for the traditional DPS business is currently handled by EDS at its
facility in Plano, Texas, with whom DPS had an agreement for these services. EDS
owns the computer hardware and operating software, and we own the application
software for these operations. EDS provides disaster recovery services for the
DPS business. We have substantial capacity for growth in our claims processing
facilities.
    
 
COMPETITION
 
   
     We believe the primary competitive factors in each of our businesses are
price, quality of service and breadth of available services. We believe our
principal competitive advantages are our size, our independence from
pharmaceutical manufacturer and drug store ownership, our strong managed care
and employer group customer base which supports the development of advanced PBM
services and our commitment to provide flexible and distinctive service to our
clients. We believe our independence from pharmaceutical manufacturer ownership
allows us to make unbiased formulary recommendations to our clients, balancing
both clinical efficacy and cost, and our independence from drug store ownership
allows us to construct a variety of convenient and cost-effective retail
pharmacy networks for our clients, without favoring any particular pharmacy
chain. Some clients have indicated that this independence has been an important
factor in their decision making process.
    
 
   
     We believe a particular growth area in the PBM industry will be medical
information management. We believe our majority owned subsidiary, Practice
Patterns Science, is an industry leader in this area, having developed
proprietary software to process and sort medical claims, prescription drug
claims and clinical laboratory data for use by managed care organizations and
other health care companies.
    
 
   
     There are a large number of companies offering PBM services in the United
States. Most of these companies are smaller than us and offer their services on
a local or regional basis. We do, however, compete with a number of large,
national companies, including Merck-Medco Managed Care, a subsidiary of Merck &
Co., PCS, a subsidiary of Rite-Aid and Caremark International, a subsidiary of
MedPartners, as well as numerous insurance and Blue Cross and Blue Shield plans
and several HMOs which have their own PBM capabilities. Several of these other
companies may have greater financial, marketing and technological resources than
us.
    
 
   
     In general, consolidation is a critical factor in the pharmaceutical
industry, and particularly so in the PBM segment. Competitors that are owned by
pharmaceutical manufacturers or drug store chains may have pricing advantages
that are unavailable to us and other independent PBMs. However, we believe
independence from pharmaceutical manufacturer and drug store ownership is
important to some of our clients, and we believe this independence provides us
an advantage in marketing to those clients.
    
 
                                       49
<PAGE>   53
 
   
     Some of our PBM services, such as disease management, informed decision
counseling and medical information management services, compete with those being
offered by pharmaceutical manufacturers, other PBMs, large national companies,
specialized disease management companies and information service providers. Our
non-PBM services compete with a number of large national companies as well as
with local providers.
    
 
SERVICE MARKS AND TRADEMARKS
 
   
     We and our subsidiaries have registered several service marks, including
"Express Scripts(R)", "ExpressComp(R)", "ExpressReview(R)", "Express
Therapeutics(R)", "IVTx(R)", "PERx(R)", "PERxCare(R)", "PERxComp(R)", "PTE(R)",
"ValueRx(R)" and "Value Health, Inc.(R)", with the United States Patent and
Trademark Office. We also acquired several additional trademarks through our
acquisition of DPS. Our rights to these marks will continue as long as we comply
with the usage, renewal filing and other legal requirements relating to the
renewal of service marks. We are in the process of applying for registration of
several other trademarks and service marks. If we are unable to obtain any
additional registrations, we believe there would be no material adverse effect
on our business.
    
 
INSURANCE
 
   
     Our PBM operations, including the dispensing of pharmaceutical products by
our mail service pharmacies, the services rendered in connection with our
disease management and informed decision counseling services and the products
and services provided in connection with our infusion therapy programs,
including the associated nursing services, have subjected us and may subject us
in the future to litigation and liability for damages. We believe our insurance
protection is adequate for our present business operations, but there can be no
assurance that we will be able to maintain our professional and general
liability insurance coverage in the future or that this insurance coverage will
be available on acceptable terms or adequate to cover any or all potential
product or professional liability claims. A successful product or professional
liability claim in excess of our insurance coverage could have a material
adverse effect upon our business.
    
 
FACILITIES AND EMPLOYEES
 
     We operate our United States and Canadian PBM and non-PBM businesses out of
leased and owned facilities throughout the United States and Canada. All of our
facilities are leased except for our Albuquerque, New Mexico facility, which we
own.
 
                                 PBM Facilities
 
                           Maryland Heights, Missouri
                              Earth City, Missouri
                                 Tempe, Arizona
                              Plymouth, Minnesota
   
                             Bloomington, Minnesota
    
                             Bensalem, Pennsylvania
   
                             Horsham, Pennsylvania
    
                                 Troy, New York
                           Farmington Hills, Michigan
                            Albuquerque, New Mexico
                              Mississauga, Ontario
 
                               Non-PBM Facilities
 
                           Maryland Heights, Missouri
   
                              Earth City, Missouri
    
                               Columbia, Missouri
                                 Dallas, Texas
                                 Houston, Texas
                               Columbia, Maryland
                                 Tempe, Arizona
                             Northvale, New Jersey
                           West Chester, Pennsylvania
 
                                       50
<PAGE>   54
 
   
     Our Maryland Heights, Missouri facility houses our corporate offices.
IVTx's corporate offices are also located at the Maryland Heights, Missouri
site. Our non-PBM specialty distribution services are operated out of our
facility in Tempe, Arizona. We believe our facilities are generally
well-maintained and are in good operating condition.
    
 
   
     During 1998, we entered into an operating lease for a new corporate
headquarters facility to be located adjacent to our existing Maryland Heights,
Missouri facility. Construction of the new building is substantially complete,
and we anticipate moving into it in May 1999. We are continuing to evaluate our
future requirements for additional space.
    
 
   
     We own computer systems for both the Maryland Heights, Missouri and Tempe,
Arizona sites. Computer systems to process the business acquired with ValueRx
are located at Perot Systems' facility in Richardson, Texas. Perot Systems
maintains the computer hardware on our behalf. The claims processing for the
traditional DPS business is currently handled by EDS at its facility in Plano,
Texas, with whom DPS has an agreement for these services. EDS owns the computer
hardware and operating software, and we own the application software for these
operations. Our software for drug utilization review and other products has been
developed internally by us or purchased under perpetual, nonexclusive license
agreements with third parties. Our computer systems at each site are extensively
integrated and share common files through local and wide area networks. An
uninterruptable power supply and diesel generator allow our computers, telephone
systems and mail pharmacy at each site to continue to function during a power
outage. To protect against loss of data and extended downtime, we store software
and redundant files at both on-site and off-site facilities on a regular basis
and have contingency operation plans in place.
    
 
   
     As of May 1, 1999, we employed a total of 4,325 employees in the United
States and 72 employees in Canada. We have approximately 375 employees who are
members of collective bargaining units. Specifically, we employ members of the
Service Employees International Union at our Bensalem, Pennsylvania facility,
members of the United Auto Workers Union at our Farmington Hills, Michigan
facility, and members of the United Food and Commercial Workers Union at our
Albuquerque, New Mexico facility. We believe our relationships with our
employees are good.
    
 
   
LEGAL PROCEEDINGS
    
 
   
     We acquired all of the outstanding capital stock of Value Health, Inc., a
Delaware corporation, and Managed Prescription Network, a Delaware corporation,
from Columbia/HCA HealthCare and its affiliates on April 1, 1998 as part of our
acquisition of ValueRx. VHI, MPN and/or their subsidiaries were party to various
legal proceedings, investigations or claims at the time of the ValueRx
acquisition. The effect of these actions on our future financial results is not
subject to reasonable estimation because considerable uncertainty exists about
the outcomes. Nevertheless, in the opinion of management, the ultimate
liabilities resulting from any of these lawsuits, investigations or claims now
pending will not materially affect our consolidated financial position, results
of operations or cash flows.
    
 
   
     ValueRx and several of its subsidiaries are party to two securities
litigation matters, Bash, et al. v. Value Health, Inc., et al., No. 3:97 cv 2711
(JCH) (D. Conn.) and Freedman, et al. v. Value Health, Inc., et al., No. 3:95 cv
2038 (JCH) (D. Conn.). The two lawsuits, each filed in 1995, allege that VHI and
other defendants made false or
    
 
                                       51
<PAGE>   55
 
   
misleading statements to the public in connection with VHI's acquisition of
Diagnostek in 1995. Neither complaint specifies the amount of damages sought. On
February 18, 1999, the court granted plaintiffs' motions for class certification
and certified a class consisting of:
    
 
   
     - all persons who purchased or otherwise acquired shares of VHI during the
       period from April 3, 1995, through and including November 7, 1995,
       including those who acquired shares issued in connection with the
       Diagnostek merger
    
 
   
     - all persons who purchased or otherwise acquired shares of Diagostek
       during the period from March 27, 1995, through and including July 28,
       1995
    
 
   
     Expert discovery is to be completed by June 17, 1999, and any dispositive
motions must be filed within 30 days after that date. In connection with the
ValueRx acquisition, Columbia has agreed to defend and hold us and our
affiliates, including VHI, harmless from and against any liability that may
arise in connection with either of these proceedings. Consequently, we do not
believe we will incur any material liability in connection with these matters.
    
 
   
     In addition, in the ordinary course of our business there have arisen
various legal proceedings, investigations or claims now pending against us and
our subsidiaries unrelated to the ValueRx acquisition. The effect of these
actions on future financial results is not subject to reasonable estimation
because considerable uncertainty exists about the outcomes. Nevertheless, in the
opinion of management, the ultimate liabilities resulting from any of these
lawsuits, investigations or claims now pending will not materially affect our
consolidated financial position, results of operations or cash flows.
    
 
   
     Since 1993, over 100 separate lawsuits have been filed by retail pharmacies
against drug manufacturers, wholesalers and PBMs challenging brand name drug
pricing practices under various state and federal antitrust laws. The suits
alleged, among other things, that the manufacturers had offered, and PBMs had
knowingly accepted, discounts and rebates on purchases of brand name
prescription drugs that violated the federal Sherman Act and the federal
Robinson-Patman Act. Some drug manufacturers settled these actions, including a
Sherman Act case brought on behalf of a nationwide class of retail pharmacies.
The class action settlements generally provided for commitments by the
manufacturers in their discounting practices to retail pharmacies. The class
action was recently dismissed as to drug manufacturers and wholesalers who did
not settle. With respect to the cases filed by plaintiffs who opted out of the
class action, while some manufacturers have settled these actions, the
settlements are not part of the public record.
    
 
   
     In August 1997, the U.S. Department of Labor requested information from DPS
concerning its contractual relationships with employer group health plans
governed by ERISA. DPS provided the requested information to the U.S. Department
of Labor, and exchanged correspondence with the U.S. Department of Labor on this
matter until August 1998. Since that time, no additional information requests or
other correspondence has been received. However, the U.S. Department of Labor
has given no indication as to its disposition of this matter, and we cannot
provide any assurance as to the ultimate outcome of this matter or what effect,
if any, it will have on our business as a result of our acquisition of DPS.
    
 
                                       52
<PAGE>   56
 
                                   MANAGEMENT
 
EXECUTIVE OFFICERS AND DIRECTORS
 
   
     Our executive officers and directors are as follows:
    
 
   
<TABLE>
<CAPTION>
NAME                                   AGE                     POSITION
- ----                                   ---                     --------
<S>                                    <C>   <C>
Howard L. Waltman....................  66    Chairman and Director
Barrett A. Toan......................  51    President, Chief Executive Officer and
                                             Director
Stuart L. Bascomb....................  57    Executive Vice President
Thomas M. Boudreau...................  47    Senior Vice President of Administration,
                                             General Counsel and Secretary
Patrick J. Byrne.....................  44    Senior Vice President Plymouth Site
                                             Operations
Robert W. (Joe) Davis................  53    Senior Vice President and Chief Information
                                               Systems Officer
Linda L. Logsdon.....................  51    Senior Vice President of Health Management
                                               Services
David A. Lowenberg...................  49    Senior Vice President and Director of Site
                                               Operations
George Paz...........................  43    Senior Vice President and Chief Financial
                                             Officer
Jean-Marc Quach......................  40    Senior Vice President and Chief of Staff
Kurt D. Blumenthal...................  54    Vice President of Finance
Joseph W. Plum.......................  52    Vice President and Chief Accounting Officer
Howard Atkins........................  48    Director
Judith E. Campbell...................  51    Director
Richard M. Kernan, Jr................  58    Director
Richard A. Norling...................  53    Director*
Frederick J. Sievert.................  51    Director
Stephen N. Steinig...................  53    Director*
Seymour Sternberg....................  55    Director
Norman Zachary.......................  72    Director*
</TABLE>
    
 
- -------------------------
 
   
* audit committee member.
    
 
   
     Mr. Waltman was elected Chairman of our board of directors in March 1992.
Mr. Waltman has been a director since our inception in September 1986. From 1983
until September 1992, Mr. Waltman was Chairman of the Board and Chief Executive
Officer of Sanus Corp. Health Systems, formerly a wholly owned subsidiary of New
York Life Insurance Company and now known as NYLCare Health Plans. From
September 1992 to December 31, 1995, Mr. Waltman served as Chairman of the Board
of NYLCare.
    
 
   
     Mr. Toan was elected our Chief Executive Officer in March 1992 and our
President and a director in October 1990. Mr. Toan has been an executive
employee since May 1989. From January 1985 to May 1989, Mr. Toan served
full-time as the Executive Director of Sanus of Missouri, a St. Louis-based HMO.
From May 1989 until March 1992, Mr. Toan spent approximately one-half of his
time performing services for us, and the remainder of his time serving Sanus.
    
 
                                       53
<PAGE>   57
 
     Mr. Bascomb was elected our Executive Vice President in March 1989, and
also served as our Chief Financial Officer and Treasurer from March 1992 until
May 1996.
 
     Mr. Boudreau was elected our Senior Vice President, General Counsel and
Secretary in October 1994. He has served as our General Counsel since June 1994.
From September 1984 until June 1994, Mr. Boudreau was a partner in the St. Louis
law firm of Husch & Eppenberger.
 
   
     Mr. Byrne was elected our Senior Vice President Plymouth Site Operations in
May 1998. From April 1996 until October 1997, Mr. Byrne served as Vice President
of Underwriting for ValueRx, and then served as Vice President and General
Manager for the National Employer Business Unit of ValueRx for the period
November 1997 until May 1998. From 1991 until March 1996, Mr. Byrne was a
Director of Finance for United HealthCare.
    
 
     Mr. Davis was elected our Senior Vice President and Chief Information
Systems Officer in September 1997. Mr. Davis served as our Director of Technical
Services and Computer Operations from July 1993 until July 1995, and as our Vice
President and General Manager of St. Louis Operations from July 1995 until
September 1997.
 
   
     Ms. Logsdon was elected our Senior Vice President of Health Management
Services in May 1997, and served as our Vice President of Demand and Disease
Management from November 1996 until May 1997. Prior to joining us in November
1996, Ms. Logsdon served as Vice President of Corporate Services and Chief
Operating Officer of United HealthCare's Midwest Companies-GenCare/Physicians
Health Plan/MetraHealth, a St. Louis-based HMO, from February 1995 to October
1996, and as Deputy Director/Vice President of GenCare Health Systems, also a
St. Louis-based HMO, from June 1992 to February 1995.
    
 
     Mr. Lowenberg was elected our Senior Vice President and Director of Site
Operations in October 1994 and our Vice President in November 1993. Mr.
Lowenberg also served as General Manager of our Tempe, Arizona facility from
March 1993 until January 1995.
 
   
     Mr. Paz joined us and was elected our Senior Vice President and Chief
Financial Officer in January 1998. Prior to joining us, Mr. Paz was a partner in
the Chicago office of Coopers & Lybrand from December 1995 to December 1997, and
served as Executive Vice President and Chief Financial Officer of Life Partners
Group, a life insurance company, from October 1993 until December 1995.
    
 
   
     Mr. Quach was elected our Senior Vice President and Chief of Staff in May
1998. Prior to joining us, Mr. Quach was the Director of Marketing for Roche
Diagnostics during the period April 1996 to May 1998. Mr. Quach served as the
Director of Pharmacy for NYLCare for the period September 1991 to April 1996.
    
 
     Mr. Blumenthal was elected our Vice President of Finance in May 1995, and
served as our Acting Chief Financial Officer from July 1996 to January 1998.
From August 1993 to February 1995, Mr. Blumenthal served as the Chief Financial
Officer of President Baking Co.
 
     Mr. Plum was elected our Vice President in October 1994, and has served as
our Chief Accounting Officer since March 1992 and our Corporate Controller since
March 1989.
 
   
     Mr. Atkins was elected a director in January 1997. He has been an Executive
Vice President and the Chief Financial Officer of New York Life since April
1996. From September 1991 until joining New York Life, Mr. Atkins was the
Executive Vice
    
                                       54
<PAGE>   58
 
   
President and Chief Financial Officer of Midlantic Bank Corporation. Mr. Atkins
is also a director of other subsidiaries of New York Life.
    
 
   
     Ms. Campbell was elected a director in November 1997. Ms. Campbell has been
a Senior Vice President and the Chief Information Officer of New York Life since
June 1997. From October 1995 until joining New York Life, Ms. Campbell was
Senior Vice President of Consumer Banking, Manager of Deposit Products, Consumer
Payments and Direct Banking of PNCBank. Ms. Campbell served as a Senior Vice
President of Midlantic Bank from May 1992 until October 1995, when Midlantic
Bank was acquired by PNCBank. Ms. Campbell is also a director of other
subsidiaries of New York Life.
    
 
   
     Mr. Kernan was elected a director in March 1992. Mr. Kernan has been an
Executive Vice President since March 1991 and the Chief Investment Officer of
New York Life since June 1997. Mr. Kernan is also Chairman of the Board of
Trustees of The Mainstay Funds Limited and the Chairman and CEO of Mainstay VP
Series Fund, both subsidiaries of New York Life, as well as a director of NYLIFE
HealthCare and other subsidiaries of New York Life.
    
 
   
     Mr. Norling was elected a director in March 1992. Mr. Norling has been the
Chief Executive Officer of Premier, the largest voluntary health care alliance
in the United States, since September 1998. From September 1997 until September
1998, Mr. Norling was the Chief Operating Officer of Premier. From July 1989
until joining Premier, Mr. Norling was the President and Chief Executive Officer
of Fairview Hospital and HealthCare Services, a regional integrated network of
hospitals, ambulatory care services and health care management enterprises.
    
 
   
     Mr. Sievert was elected a director in July 1995. Since January 1997, Mr.
Sievert has been the Vice Chairman of New York Life. From February 1995 to
December 1996, Mr. Sievert was an Executive Vice President of New York Life.
From January 1992 to January 1995, Mr. Sievert was Senior Vice President of New
York Life in charge of financial management and policyholder services for
Individual Operations. Mr. Sievert is also a director or an officer of other
subsidiaries of New York Life.
    
 
   
     Mr. Steinig was elected a director in January 1994. Since February 1994,
Mr. Steinig has been Senior Vice President and Chief Actuary of New York Life.
From February 1992 to February 1994, Mr. Steinig was Chief Actuary and
Controller of New York Life. Mr. Steinig is also an officer of other
subsidiaries of New York Life.
    
 
   
     Mr. Sternberg was elected a director in March 1992. Mr. Sternberg is the
Chairman, President and Chief Executive Officer of New York Life. Mr. Sternberg
has been with New York Life since February 1989, serving as the President and
Chief Operating Officer from October 1995 to April 1997, the Vice Chairman from
February 1995 to September 1995 and as an Executive Vice President from March
1992 to February 1995. Mr. Sternberg is also Chairman, Chief Executive Officer
and President of NYLIFE HealthCare, and a director or an officer of other
subsidiaries of New York Life.
    
 
   
     Mr. Zachary was elected a director in March 1992. From June 1967 to
November 1991, Mr. Zachary held various positions at Logica Data Architects,
formerly known as Data Architects, a consulting and software development
company, including serving as President and a director until November 1990.
Logica has provided consulting services to New York Life from time to time.
    
 
                                       55
<PAGE>   59
 
                             PRINCIPAL STOCKHOLDERS
 
   
     The following table sets forth information regarding the beneficial
ownership of our Class A and Class B common stock as of March 1, 1999 (unless
otherwise noted) by:
    
 
   
     - each person known by us to own beneficially more than five percent of the
       outstanding shares of Class A or Class B common stock
    
 
   
     - each of our five most highly compensated executive officers and each of
       our directors
    
 
   
     - all of our executive officers and directors as a group
    
 
   
Included are amounts of shares which may be acquired on March 1, 1999 or within
60 days of March 1, 1999 pursuant to the exercise of stock options by executive
officers or outside directors. Unless otherwise indicated, each of the persons
or entities listed below exercises sole voting and investment power over the
shares that each of them beneficially owns. All beneficial stockholders other
than New York Life, the parent of NYLIFE HealthCare, own shares of Class A
common stock. New York Life, as beneficial owner, owns all of the outstanding
shares of Class B common stock.
    
 
   
<TABLE>
<CAPTION>
                                                          AMOUNT AND                           PERCENT OF CLASS
                                                          NATURE OF                         ----------------------
                                                          BENEFICIAL                        PRIOR TO       AFTER
NAME AND ADDRESS                                          OWNERSHIP                         OFFERING      OFFERING
- ----------------                                          ----------                        --------      --------
<S>                                                       <C>                               <C>           <C>
Class A common stock:
  Howard Atkins.........................................           0                             *
  Judith E. Campbell....................................           0                             *
  Richard M. Kernan, Jr.................................           0                             *
  Richard A. Norling....................................      48,000(1)                          *
  Frederick J. Sievert..................................           0                             *
  Stephen N. Steinig....................................           0                             *
  Seymour Sternberg.....................................       6,000(2)                          *
  Barrett A. Toan.......................................     372,592(3)                        2.0%
  Howard L. Waltman.....................................      19,200(4)                          *
  Norman Zachary........................................      34,000(5)                          *
  Stuart L. Bascomb.....................................      63,493(6)                          *
  Patrick J. Byrne......................................          20(7)                          *
  David A. Lowenberg....................................      68,602(8)                          *
  George Paz............................................      21,039(9)                          *
  Directors and Executive Officers as a Group
    (18 persons)........................................     792,345(10)                       4.3%
  Pilgrim Baxter & Associates, Ltd......................   2,481,100(11)                      13.3%
    825 Duportail Road
    Wayne, Pennsylvania 19087
  AMVESCAP PLC..........................................   2,229,600(12)                      11.9%
    1 Devonshire Square
    London, England EC2M4YR
Class B common stock:
  NYLIFE HealthCare Management, Inc.....................  15,020,000(13)(14)(15)             100.0%        100.0%
    51 Madison Avenue
    New York, New York 10010
</TABLE>
    
 
                                       56
<PAGE>   60
 
- -------------------------
  *  Indicates less than 1%.
 
   
 (1) Consists of options for 48,000 shares granted under the Amended and
     Restated 1992 Stock Option Plan for Outside Directors.
    
 
 (2) Excludes 360 shares held by Mr. Sternberg's son, as to which shares Mr.
     Sternberg disclaims beneficial ownership.
 
   
 (3) Includes options for 348,000 shares granted under our Amended and Restated
     1992 Employee Stock Option Plan and our Amended and Restated 1994 Employee
     Stock Option Plan. The shares subject to the options are restricted from
     transfer with the transfer restriction lapsing as to 20% of the original
     number thereof on each anniversary date of the date of grant. Under the
     terms of Mr. Toan's employment agreement, the transfer restriction is
     subject to complete lapse in the event of a "Change of Control" (as defined
     in the agreement) or termination of Mr. Toan's employment by us without
     "Cause" (as defined in the agreement), by Mr. Toan for "Good Reason" (as
     defined in the agreement) or by reason of death, disability or retirement.
     Pursuant to his employment agreement, Mr. Toan may also have the right to
     require us to purchase a portion of his shares within 12 months after his
     termination of employment without Cause, for Good Reason or upon death or
     disability. Upon termination of Mr. Toan's employment, we will purchase any
     shares issued upon the exercise of the options that remain subject to the
     transfer restriction at the lesser of the option exercise price or the then
     current market value of the Class A common stock. Also included are 592
     hypothetical share equivalents invested in the Express Scripts Stock Fund
     under our Executive Deferred Compensation Plan, calculated as of March 1,
     1999, using the February 26, 1999 per share closing price as reported on
     The Nasdaq National Market.
    
 
 (4) Consists of options for 19,200 shares granted under the Outside Directors
     Plan.
 
 (5) Consists of options for 34,000 shares granted under the Outside Directors
     Plan.
 
   
 (6) Includes options for 51,680 shares granted under the Employee Plans, 10,300
     shares owned by Mr. Bascomb, of which 3,300 shares are held as co-trustee,
     with shared voting and dispositive power, of a trust for the benefit of his
     mother, and 1,513 hypothetical share equivalents invested in the Stock Fund
     under the Deferred Compensation Plan, calculated as of March 1, 1999, using
     the February 26, 1999 per share closing price as reported on The Nasdaq
     National Market.
    
 
   
 (7) Consists of 20 hypothetical share equivalents invested in the Stock Fund
     under the Deferred Compensation Plan, calculated as of March 1, 1999, using
     the February 26, 1999 per share closing price as reported on The Nasdaq
     National Market.
    
 
   
 (8) Consists of options for 68,440 shares granted under the Employee Plans, and
     162 hypothetical share equivalents invested in the Stock Fund under the
     Deferred Compensation Plan, calculated as of March 1, 1999, using the
     February 26, 1999 per share closing price as reported on The Nasdaq
     National Market.
    
 
   
 (9) Consists of options for 21,000 shares granted under the Employee Plans, and
     39 hypothetical share equivalents invested in the Stock Fund under the
     Deferred Compensation Plan, calculated as of March 1, 1999, using the
     February 26, 1999 per share closing price as reported on The Nasdaq
     National Market.
    
 
   
(10) Includes options for 749,450 shares granted under the Outside Directors
     Plan and the Employee Plans, and 2,645 hypothetical share equivalents
     invested in the Stock Fund under the Deferred Compensation Plan, calculated
     as of March 1, 1999, using the February 26, 1999 per share closing price as
     reported on The Nasdaq National Market.
    
 
   
(11) The information with respect to the beneficial ownership of these shares is
     as of December 31, 1998 and has been obtained from Amendment No. 10 to
     Schedule 13G dated February 10, 1999. The schedule reports that the
     beneficial owner is a registered investment advisor and shares voting power
     with respect to all of the shares reported but has sole dispositive power
     as to all of the shares reported.
    
 
   
(12) The information with respect to the beneficial ownership of these shares is
     as of December 31, 1998 and has been obtained from Amendment No. 2 to
     Schedule 13G dated February 10, 1999. The schedule reports that the
     beneficial owner is a parent holding company and shares voting power and
     dispositive power as to all of the shares reported.
    
 
   
(13) Messrs. Atkins, Kernan, Sievert, Steinig and Sternberg, and Ms. Campbell,
     our directors, are also directors and/or hold various executive positions
     with New York Life and/or NYLIFE HealthCare. All of these directors
     disclaim beneficial ownership of our Class B common stock owned by NYLIFE
     HealthCare.
    
 
   
(14) NYLIFE HealthCare holds 15,020,000 shares of Class B common stock, which
     automatically convert upon transfer by NYLIFE HealthCare to any entity
     other than an affiliate of NYLIFE HealthCare at any time into shares of
     Class A common stock on a share-for-share basis and otherwise at the option
     of NYLIFE HealthCare.
    
 
   
(15) If converted to Class A common stock, the Class B common stock would
     represent approximately     % of the outstanding Class A common stock.
    
                                       57
<PAGE>   61
 
                          DESCRIPTION OF CAPITAL STOCK
 
   
     Our authorized capital stock consists of 75,000,000 shares of Class A
common stock, par value $.01 per share, 22,000,000 shares of Class B common
stock, par value $0.01 per share, and 5,000,000 shares of preferred stock, par
value $0.01 per share.
    
 
COMMON STOCK
 
   
     As of March 1, 1999, 18,681,130 shares of Class A common stock were issued
and 18,206,130 shares were outstanding, and 15,020,000 shares of Class B common
stock were issued and outstanding. The outstanding Class A common stock is, and
the Class A common stock offered by this prospectus when issued and paid for
will be, fully paid and non-assessable.
    
 
   
     DIVIDENDS.  Dividends on the common stock will be paid if, when and as
determined by our board of directors out of funds legally available for this
purpose. Holders of Class A and Class B common stock have the same rights
regarding dividends.
    
 
   
     VOTING RIGHTS.  Holders of Class A common stock are entitled to one vote
for each share held by them on all matters presented to stockholders. Pursuant
to our certificate of incorporation, the holders of Class B common stock have
ten votes per share. As a result of the disproportionate voting rights given to
holders of Class B common stock, NYLIFE HealthCare could reduce its investment
to slightly less than 10% of our common stock and still control us with a
majority of the combined voting power of our common stock. The affirmative vote
of the holders of a majority of the outstanding Class A common stock is required
for an amendment of the by-laws that would alter the requirement that a majority
of the directors on the audit committee be persons who are not directors of New
York Life or its subsidiaries, other than us, or officers or employees of New
York Life or its subsidiaries, other than us. Our stockholders do not have
cumulative voting rights with respect to the election of directors. Our by-laws
provide for notice requirements for stockholder nominations and proposals at
annual meetings and preclude stockholders holding less than 50% of all
outstanding voting shares from bringing business before any special meeting. No
action required or permitted to be taken at an annual or special meeting of our
stockholders may be taken by written consent without a meeting. We have elected
not to be subject to Section 203 of the General Corporation Law of the State of
Delaware, which prohibits some publicly held Delaware corporations from engaging
in a business combination with an interested stockholder. An interested
stockholder is any person or entity who, together with affiliates and
associates, owns, or within the three immediately preceding years did own, 15%
or more of a corporation's voting stock.
    
 
   
     LIQUIDATION RIGHTS.  After satisfaction of the preferential liquidation
rights of any preferred stock, the holders of the Class A and Class B common
stock are entitled to share, ratably, in the distribution of all remaining net
assets.
    
 
   
     PREEMPTIVE AND OTHER RIGHTS.  Other than Premier, the holders of common
stock do not have preemptive rights as to additional issues of common stock or,
other than the Class B common stock, conversion rights. Premier has preemptive
rights for selected underwritten issuances of our Class A common stock, which
have been waived in connection with this offering. The shares of common stock
are not subject to redemption or to any further calls or assessments and are not
entitled to the benefit of any sinking fund provisions.
    
 
                                       58
<PAGE>   62
 
PREFERRED STOCK
 
   
     Our certificate of incorporation authorizes our board of directors to issue
from time to time, in one or more series, shares of preferred stock with the
designations and preferences, relative voting rights -- except that voting
rights, if any, in respect of the election of directors shall be limited to
voting with the holders of Class A and Class B common stock, as a single class,
with no more than one vote per share of preferred stock -- redemption,
conversion, participation and other rights and qualifications, limitations and
restrictions permitted by law. No shares of preferred stock have been issued.
    
 
                                       59
<PAGE>   63
 
                     DESCRIPTION OF THE NEW CREDIT FACILITY
 
GENERAL
 
   
     In connection with the DPS acquisition, on April 1, 1999 we entered into a
new credit facility with a group of lenders, including Credit Suisse First
Boston, an affiliate of Credit Suisse First Boston Corporation, as lead
arranger, administrative agent and collateral agent and Bankers Trust Company,
an affiliate of BT Alex. Brown Incorporated, as syndication agent.
    
 
   
     The lenders under the new credit facility provided us $1.05 billion in
senior secured loans, consisting of $750 million in term loans, which includes
$285 million of Term A loans, $465 million of Term B loans and a $300 million
revolving credit facility. The Term A loans will mature on March 31, 2005 and
the Term B loans will mature on March 31, 2007. The revolving credit facility
will be available on a revolving basis until March 31, 2005.
    
 
   
     We applied approximately $940 million in proceeds from the new credit
facility to consummate the DPS acquisition, refinance indebtedness and pay
related fees and expenses.
    
 
GUARANTEES AND SECURITY
 
   
     The new credit facility is guaranteed by each of our existing and
subsequently acquired domestic subsidiaries, excluding Practice Patterns
Science, Great Plains Reinsurance Company, ValueRx of Michigan, Diversified NY
IPA and Diversified Pharmaceutical Services (Puerto Rico). The new credit
facility is secured by a first priority pledge of all the capital stock of each
of our existing and subsequently acquired domestic subsidiaries, other than the
excluded subsidiaries, and 65% of the stock of each of our foreign subsidiaries.
In addition, in the event that within six months of the new credit facility's
closing date we have not attained a ratio of Consolidated Total Debt to
Consolidated EBITDA, as defined in the new credit facility, of less than 3.5 to
1.0, or the indebtedness under the new credit facility has not received an
investment grade rating, we must grant a first priority security interest in,
and mortgages on, substantially all of our and our subsidiaries' tangible and
intangible assets.
    
 
INTEREST RATES
 
   
     Interest on the loans under the new credit facility accrues at a specified
margin above either the London Interbank Offered Rate or an alternate base rate,
the higher of Credit Suisse First Boston's prime rate or the federal funds rate
plus 0.5%. For LIBOR-based loans the applicable margin for the Term A loans and
revolving loans will initially be 2.75% per annum, and for the Term B loans the
applicable margin will initially be 3.50% per annum. During the continuance of
any event of default, interest will accrue at the applicable interest rate plus
2.0% per annum.
    
 
COVENANTS
 
   
     The new credit facility contains customary affirmative and negative
covenants, including limitations on indebtedness, liens, investments, dividends,
stock repurchases and other specified transactions and payments. These covenants
also include a specified minimum interest coverage ratio, a maximum ratio of
total debt to EBITDA, as defined in the new credit facility, and a minimum fixed
charge coverage ratio.
    
 
                                       60
<PAGE>   64
 
EVENTS OF DEFAULT
 
   
     The new credit facility specifies various customary events of default
including nonpayment of principal, interest or fees, violation of covenants,
incorrectness of representations and warranties and events such as a change of
control or bankruptcy.
    
 
                                       61
<PAGE>   65
 
                                  UNDERWRITING
 
   
     Under the terms and subject to the conditions contained in an underwriting
agreement dated           , 1999, the underwriters named below, for whom Credit
Suisse First Boston Corporation, BT Alex. Brown Incorporated and Morgan Keegan &
Company, Inc. are acting as representatives, have severally, but not jointly,
agreed to purchase from us the following respective numbers of shares of our
Class A common stock:
    
 
<TABLE>
<CAPTION>
                                                        NUMBER
UNDERWRITER                                            OF SHARES
- -----------                                            ---------
<S>                                                    <C>
Credit Suisse First Boston Corporation.............
BT Alex. Brown Incorporated........................
Morgan Keegan & Company, Inc. .....................
 
                                                       --------
     Total.........................................
                                                       ========
</TABLE>
 
   
     The underwriting agreement provides that the obligations of the
underwriters are subject to conditions precedent described in the underwriting
agreement, and that the underwriters will be obligated to purchase all of the
shares of our Class A common stock offered by this prospectus, other than those
shares covered by the over-allotment option described below, if any are
purchased. The underwriting agreement provides that, in the event of a default
by an underwriter, in some circumstances the purchase commitments of
non-defaulting underwriters may be increased or the underwriting agreement may
be terminated.
    
 
   
     We have granted to the underwriters an option exercisable by Credit Suisse
First Boston Corporation, expiring at the close of business on the 30th day
after the date of this prospectus, to purchase up to      additional shares of
our Class A common stock at the offering price, less underwriting discounts and
commissions, all as set forth on the cover page of this prospectus. This option
may be exercised only to cover over-allotments in the sale of the shares of our
Class A common stock. To the extent that the option is exercised, each
underwriter will become obligated, subject to conditions, to purchase
approximately the same percentage of the additional shares of our Class A common
stock as it was obligated to purchase pursuant to the underwriting agreement.
    
 
   
     We have been advised by the representatives that the underwriters propose
to offer the shares of our Class A common stock to the public initially at the
public offering price set forth on the cover page of this prospectus and,
through the representatives, to selling group members at this price less a
concession of $     per share, and the underwriters and any selling group
members may allow a discount of $     per share on sales to selected other
broker/dealers. After the offering, the public offering price and concession and
discount to dealers may be changed by the representatives.
    
 
                                       62
<PAGE>   66
 
     The following table summarizes the compensation to be paid to the
underwriters by us and the expenses payable by us.
 
<TABLE>
<CAPTION>
                                                WITHOUT             WITH
                                PER SHARE    OVER-ALLOTMENT    OVER-ALLOTMENT
                                ---------    --------------    --------------
<S>                             <C>          <C>               <C>
Underwriting Discounts and
  Commissions paid by Express
  Scripts, Inc................      $              $                 $
Expenses payable by Express
  Scripts, Inc................      $              $                 $
</TABLE>
 
   
     We and several of our directors, officers and shareholders (including
NYLIFE HealthCare) have agreed not to offer, sell, contract to sell, announce an
intention to sell, pledge or otherwise dispose of, directly or indirectly, or,
in our case, file with the SEC a registration statement under the Securities Act
relating to any additional shares of our common stock or securities convertible
into or exchangeable or exercisable for any shares of our common stock, without
the prior written consent of Credit Suisse First Boston Corporation for a period
of 90 days after the date of this prospectus.
    
 
   
     We have agreed to indemnify the underwriters against various liabilities,
including civil liabilities under the Securities Act, or contribute to payments
that the underwriters may be required to make in respect of these liabilities.
    
 
   
     Our Class A common stock is listed on The Nasdaq National Market under the
symbol "ESRX."
    
 
   
     The representatives, on behalf of the underwriters, may engage in
over-allotment, stabilizing transactions, syndicate covering transactions,
penalty bids and "passive" market making in accordance with Regulation M under
the Exchange Act. Over-allotment involves syndicate sales in excess of the
offering size, which creates a syndicate short position. Stabilizing
transactions permit bids to purchase the underlying security so long as the
stabilizing bids do not exceed a specified maximum. Syndicate covering
transactions involve purchases of the shares of our Class A common stock in the
open market after the distribution has been completed in order to cover
syndicate short positions. Penalty bids permit the representatives to reclaim a
selling concession from a syndicate member when the shares of our Class A common
stock originally sold by a syndicate member are purchased in a syndicate
covering transaction to cover syndicate short positions. In "passive" market
making, market makers in our Class A common stock who are underwriters or
prospective underwriters may, subject to limitations, make bids for or purchases
of our Class A common stock until the time, if any, at which a stabilizing bid
is made. These stabilizing transactions, syndicate covering transactions and
penalty bids may cause the price of our Class A common stock to be higher than
it would otherwise be in the absence of these transactions. These transactions
may be effected on The Nasdaq National Market or otherwise and, if commenced,
may be discontinued at any time.
    
 
   
     Credit Suisse First Boston, an affiliate of Credit Suisse First Boston
Corporation, is an agent and a lender, and Bankers Trust Company, an affiliate
of BT Alex. Brown Incorporated, is a lender, under our $150 million senior
subordinated bridge credit facility. Credit Suisse First Boston and Bankers
Trust Company are also agents and lenders under our $1.05 billion credit
facility. In addition, Credit Suisse First Boston Corporation acted as financial
advisor to us in connection with our acquisition of DPS. In each case, Credit
Suisse First Boston Corporation, Credit Suisse First Boston and Bankers Trust
Company will receive fees in connection with these services. We have also agreed
to pay Credit
    
 
                                       63
<PAGE>   67
 
   
Suisse First Boston Corporation and BT Alex. Brown Incorporated a financial
advisory fee of approximately $3.4 million if this offering is consummated on or
before August 1, 1999. In addition, we have agreed to pay Credit Suisse First
Boston and Bankers Trust Company a fee of approximately $3.4 million if the $150
million senior subordinated bridge credit facility is not repaid in full on or
prior to August 1, 1999. Some of the underwriters have provided other advisory
and investment banking services to us in the past, for which customary
compensation has been received.
    
 
   
     The provisions of Rule 2710(c)(8) of the NASD Conduct Rules apply to this
offering. As described under "Use of Proceeds," the net proceeds of this
offering, after deducting underwriting discounts and commissions and offering
expenses, will be applied to repay our $150 million senior subordinated bridge
credit facility and a portion of the indebtedness under our $1.05 billion credit
facility. Under Rule 2710(c)(8), when an NASD member such as Credit Suisse First
Boston Corporation and BT Alex. Brown Incorporated participate in a distribution
of equity securities and more than 10% of the net proceeds of the distribution
is to be paid to a member or its affiliates, one of the following two criteria
must be met:
    
 
   
        - the price of the equity securities can be no higher than that
          recommended by a "qualified independent underwriter"
    
 
   
        - the offering must be for a class of equity securities for which a
          "bona fide independent market" exists
    
 
   
Because a "bona fide independent market" for our Class A common stock exists,
the public offering price of our Class A common stock offered by this prospectus
will not be passed upon by a "qualified independent underwriter."
    
 
   
     We are currently in compliance in all material respects with the terms of
our $150 million senior subordinated bridge credit facility and our $1.05
billion credit facility. The decision of Credit Suisse First Boston Corporation
and BT Alex. Brown Incorporated to distribute our Class A common stock offered
by this prospectus was made independently of Credit Suisse First Boston and
Bankers Trust Company, which had no involvement in determining whether or when
to distribute our Class A common stock under the terms of this offering. Credit
Suisse First Boston Corporation and BT Alex. Brown Incorporated will not receive
any benefit from this offering other than their respective portions of the
underwriting discounts and commissions paid by us.
    
 
   
                          NOTICE TO CANADIAN RESIDENTS
    
 
   
RESALE RESTRICTIONS
    
 
   
     The distribution of the Class A common stock in Canada is being made only
on a private placement basis exempt from the requirement that we prepare and
file a prospectus with the securities regulatory authorities in each province
where trades of the Class A common stock are effected. Accordingly, any resale
of the Class A common stock in Canada must be made in accordance with applicable
securities laws which will vary depending on the relevant jurisdiction, and
which may require resales to be made in accordance with available statutory
exemptions or pursuant to a discretionary exemption granted by the applicable
Canadian securities regulatory authority. Purchasers are advised to seek legal
advice prior to any resale of the Class A common stock.
    
 
                                       64
<PAGE>   68
 
   
REPRESENTATIONS OF PURCHASERS
    
 
   
     Each purchaser of the Class A common stock in Canada who receives a
purchase confirmation will be deemed to represent to we and the dealer from whom
such purchase confirmation is received that (1) such purchaser is entitled under
applicable provincial securities laws to purchase such Class A common stock
without the benefit of a prospectus qualified under such securities laws, (2)
where required by law, that such purchaser is purchasing as principal and not an
agent and (3) such purchaser has reviewed the text under "-- Resale
Restrictions."
    
 
   
RIGHTS OF ACTION (ONTARIO PURCHASERS)
    
 
   
     The securities being offered are those of a foreign issuer and Ontario
purchasers will not receive the contractual right of action prescribed by
Ontario securities laws. As a result, Ontario purchasers must rely on other
remedies that may be available, including common law rights of action for
damages or rescission or rights of action under the civil liability provisions
of the United States federal securities laws.
    
 
   
ENFORCEMENT OF LEGAL RIGHTS
    
 
   
     All of the issuer's directors and officers as well as the experts named
herein may be located outside of Canada and, as a result, it may not be possible
for Canadian purchasers to effect service of process within Canada upon the
issuer or such persons. All or a substantial portion of the assets of the issuer
and such persons may be located outside of Canada and, as a result, it may not
be possible to satisfy a judgment against the issuer or such persons in Canada
or to enforce a judgment obtained in Canadian courts against such issuer or
persons outside of Canada.
    
 
   
NOTICE TO BRITISH COLUMBIA RESIDENTS
    
 
   
     A purchaser of Class A common stock to whom the Securities Act (British
Columbia) applies is advised that such purchaser is required to file with the
British Columbia Securities Commission a report within ten days of the sale of
any Class A common stock acquired by such purchaser pursuant to this offering.
Such report must be in the form attached to British Columbia Securities
Commission Blanket Order BOR #95/17, a copy of which may be obtained from us.
Only one such report must be filed in respect of Class A common stock acquired
on the same date and under the same prospectus exemption.
    
 
   
TAXATION AND ELIGIBILITY FOR INVESTMENT
    
 
   
     Canadian purchasers of Class A common stock should consult their own legal
and tax advisors with respect to the tax consequences of an investment in the
Class A common stock in their particular circumstances and with respect to the
eligibility of the Class A common stock for investment by the purchaser under
relevant Canadian legislation.
    
 
                           FORWARD-LOOKING STATEMENTS
 
   
     This prospectus and the documents incorporated in this prospectus by
reference include forward-looking statements under the Securities Act. In
addition, from time to time, we or our representatives have made or may make
forward-looking statements orally or in writing. The words "may," "will,"
"expect," "anticipate," "believe," "estimate," "plan," "intend" and similar
expressions have been used in this prospectus and the documents incorporated in
this prospectus by reference to identify forward-looking
    
 
                                       65
<PAGE>   69
 
   
statements. We have based these forward-looking statements on our current views
with respect to future events and financial performance. Actual results could
differ materially from those projected in the forward-looking statements. These
forward-looking statements are subject to risks, uncertainties and assumptions,
including, among other things:
    
 
   
     - risks associated with the consummation and financing of our acquisitions
       of ValueRx and DPS, including the ability to successfully integrate the
       operations of the acquired businesses with our existing operations,
       client retention issues and risks inherent in the acquired entities
       operations
    
 
     - risks associated with managing and maintaining internal growth
 
     - competition, including price competition, competition in the bidding and
       proposal process and our ability to consummate contract negotiations with
       prospective clients
 
   
     - the possible termination of contracts with key clients or providers
    
 
   
     - the possible loss of relationships with pharmaceutical manufacturers
    
 
     - changes in pricing or discount practices of pharmaceutical manufacturers
 
     - adverse results in litigation and regulatory matters, the adoption of
       adverse legislation or regulations, more aggressive enforcement of
       existing legislation or regulations or a change in the interpretation of
       existing legislation or regulations
 
     - the impact of increases in health care costs, changes in drug utilization
       patterns and introductions of new drugs
 
   
     - risks associated with the "year 2000" issue, including our ability to
       successfully convert our and DPS's information systems and our and DPS's
       non-information systems, and the ability of our and DPS's vendors/trading
       partners to successfully convert their systems to be Year 2000 compliant
    
 
     - dependence on key members of management
 
   
     - our relationship with New York Life, which possesses voting control of us
    
 
     - other risks described from time to time in our filings with the SEC
 
   
     We are not obligated to update or revise any forward-looking statements,
whether as a result of new information, future events or otherwise. All
subsequent written and oral forward-looking statements attributable to us or
persons acting on our behalf are expressly qualified in their entirety by the
cautionary statements contained throughout this prospectus and the documents
incorporated in this prospectus by reference. Because of these risks,
uncertainties and assumptions, you should not place undue reliance on these
forward-looking statements.
    
 
                                       66
<PAGE>   70
 
                      WHERE YOU CAN FIND MORE INFORMATION
 
   
     We file annual, quarterly and special reports, proxy statements and other
information with the SEC under the Exchange Act. The Exchange Act file number
for our SEC filings is 000-20199. You may read and copy any document we file at
the following SEC public reference rooms:
    
 
<TABLE>
  <S>                     <C>                         <C>
  Judiciary Plaza         500 West Madison Street     7 World Trade Center
  450 Fifth Street, N.W.  14th Floor                  Suite 1300
  Room 1024               Chicago, Illinois 60661     New York, New York 10048
  Washington, D.C. 20549
</TABLE>
 
     You may obtain information on the operation of the public reference room in
Washington, D.C. by calling the SEC at 1-800-SEC-0330.
 
   
     We file information electronically with the SEC. Our SEC filings also are
available from the SEC's Internet site at http://www.sec.gov, which contains
reports, proxy and information statements and other information regarding
issuers that file electronically. Our Class A common stock is listed on The
Nasdaq National Market.
    
 
     You may also read and copy our SEC filings and other information at the
offices of Nasdaq Operations, 1735 K Street, N.W., Washington, D.C. 20006.
 
   
     This prospectus is part of a registration statement we filed with the SEC.
The SEC allows us to "incorporate by reference" selected documents we file with
it, which means that we can disclose important information to you by referring
you to those documents. The information in the documents incorporated by
reference is considered to be part of this prospectus, and information in
documents that we file later with the SEC will automatically update and
supersede this information. We incorporate by reference the documents listed
below and any future filings we will make with the SEC under Section 13(a),
13(c), 14 or 15(d) of the Exchange Act:
    
 
   
     - Annual Report on Form 10-K for the fiscal year ended December 31, 1998
    
 
   
     - Current Reports on Form 8-K dated February 18, 1999, February 24, 1999,
       March 25, 1999 and April 14, 1999
    
 
     - Description of Common Stock contained in Registration Statement on Form
       8-A dated May 12, 1992
 
     We will provide a copy of the documents we incorporate by reference, at no
cost, to any person who receives this prospectus, including any beneficial owner
of our common stock. To request a copy of any or all of these documents, you
should write or telephone us at the following address and telephone number:
 
     General Counsel
     Express Scripts, Inc.
     14000 Riverport Drive
     Maryland Heights, Missouri 63043
     Telephone: (314) 770-1666
 
                                       67
<PAGE>   71
 
                                    LEGAL MATTERS
 
   
     The validity of the Class A common stock being offered by this prospectus
is being passed upon for us by Thomas M. Boudreau, Senior Vice President,
General Counsel and Secretary, and by Simpson Thacher & Bartlett, New York, New
York, and for the underwriters by Cahill Gordon & Reindel, a partnership
including a professional corporation, New York, New York.
    
 
                                    EXPERTS
 
   
     The Express Scripts, Inc. and Diversified Pharmaceutical Services, Inc. and
Subsidiary Financial Statements as of December 31, 1998 and 1997 and for each of
the three years in the period ended December 31, 1998 included in this
prospectus and the Value Health Pharmacy Benefit Management Financial Statements
as of December 31, 1996 and for each of the two years in the period ended
December 31, 1996 incorporated by reference in this prospectus have been
included in reliance on the reports of PricewaterhouseCoopers LLP, independent
accountants, given on the authority of that firm as experts in auditing and
accounting.
    
 
   
     The Value Health Pharmacy Benefit Management Financial Statements as of
December 31, 1997 and for the five-month period ended December 31, 1997 and for
the seven-month period ended July 31, 1997 and the Managed Prescription Network,
Inc. Financial Statements as of December 31, 1997 and 1996 and for each of the
three years in the period ended December 31, 1997 incorporated by reference in
this prospectus have been so included from our current report on Form 8-K/A
dated June 12, 1998 in reliance on the reports of Ernst & Young LLP, independent
accountants, given on the authority of that firm as experts in auditing and
accounting.
    
 
                                       68
<PAGE>   72
 
                         INDEX TO FINANCIAL STATEMENTS
 
                             EXPRESS SCRIPTS, INC.
                       CONSOLIDATED FINANCIAL STATEMENTS
 
<TABLE>
<S>                                   <C>
Report of Independent Accountants...   F-3
Consolidated Balance Sheet..........   F-4
Consolidated Statement of
  Operations........................   F-5
Consolidated Statement of Changes in
  Stockholders' Equity..............   F-6
Consolidated Statement of Cash
  Flows.............................   F-7
Notes to Consolidated Financial
  Statements........................   F-8
</TABLE>
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
                              FINANCIAL STATEMENTS
 
   
<TABLE>
<S>                                   <C>
Report of Independent Accountants...  F-31
Balance Sheets......................  F-32
Statements of Operations............  F-33
Statements of Stockholder's
  Equity............................  F-34
Statements of Cash Flows............  F-35
Notes to Financial Statements.......  F-36
</TABLE>
    
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
      MANAGED PRESCRIPTION NETWORK, INC. D/B/A COLUMBIA PHARMACY SOLUTIONS
               UNAUDITED COMBINED CONDENSED FINANCIAL STATEMENTS
 
   
<TABLE>
<S>                                   <C>
Combined Condensed Balance Sheet....  F-47
Combined Condensed Statement of
  Operations........................  F-48
Combined Condensed Statement of Cash
  Flows.............................  F-49
Notes to Combined Condensed
  Financial Statements..............  F-50
</TABLE>
    
 
                                       F-1
<PAGE>   73
 
                             EXPRESS SCRIPTS, INC.
 
                       CONSOLIDATED FINANCIAL STATEMENTS
 
                      AS OF DECEMBER 31, 1997 AND 1998 AND
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1997 AND 1998
 
                                       F-2
<PAGE>   74
 
                       REPORT OF INDEPENDENT ACCOUNTANTS
 
To the Board of Directors and
Stockholders of Express Scripts, Inc.
 
     In our opinion, the accompanying consolidated balance sheet and the related
consolidated statements of operations, of changes in stockholders' equity and of
cash flows present fairly, in all material respects, the financial position of
Express Scripts, Inc. and its subsidiaries at December 31, 1998 and 1997, and
the results of their operations and their cash flows for each of the three years
in the period ended December 31, 1998, in conformity with generally accepted
accounting principles. These financial statements are the responsibility of the
Company's management; our responsibility is to express an opinion on these
financial statements based on our audits. We conducted our audits of these
statements in accordance with generally accepted auditing standards which
require that we plan and perform the audit to obtain reasonable assurance about
whether the financial statements are free of material misstatement. An audit
includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements, assessing the accounting principles
used and significant estimates made by management, and evaluating the overall
financial statement presentation. We believe that our audits provide a
reasonable basis for the opinion expressed above.
 
PRICEWATERHOUSECOOPERS LLP
 
St. Louis, Missouri
February 12, 1999
 
                                       F-3
<PAGE>   75
 
                             EXPRESS SCRIPTS, INC.
 
                           CONSOLIDATED BALANCE SHEET
 
   
<TABLE>
<CAPTION>
                                                                   DECEMBER 31,
                                                              ----------------------
                                                                1997         1998
                                                                ----         ----
                                                                  (IN THOUSANDS,
                                                                EXCEPT SHARE DATA)
<S>                                                           <C>         <C>
ASSETS
Current assets:
  Cash and cash equivalents.................................  $ 64,155    $  122,589
  Short-term investments....................................    57,938
  Receivables, less allowance for doubtful accounts of
    $4,802 and $17,806, respectively
  Unrelated parties.........................................   194,061       433,006
  Related parties...........................................    16,230
  Inventories...............................................    28,935        55,634
  Deferred taxes............................................     2,303        41,011
  Prepaid expenses..........................................       346         4,667
                                                              --------    ----------
    Total current assets....................................   363,968       656,907
Property and equipment, less accumulated depreciation and
  amortization..............................................    26,821        77,499
Goodwill, less accumulated amortization.....................       251       282,163
Other assets................................................    11,468        78,892
                                                              --------    ----------
    Total assets............................................  $402,508    $1,095,461
                                                              ========    ==========
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
  Current maturities of long-term debt......................  $     --    $   54,000
  Claims and rebates payable................................   164,920       338,251
  Accounts payable..........................................    17,979        60,247
  Accrued expenses..........................................    15,007        86,798
                                                              --------    ----------
    Total current liabilities...............................   197,906       539,296
Long-term debt..............................................                 306,000
Other liabilities...........................................       901           471
                                                              --------    ----------
    Total liabilities.......................................   198,807       845,767
                                                              --------    ----------
Commitments and Contingencies (Notes 3, 9 and 15)
 
STOCKHOLDERS' EQUITY:
  Preferred stock, $.01 par value, 5,000,000 shares
    authorized, and no shares issued and outstanding........
  Class A Common Stock, $.01 par value, 75,000,000 shares
    authorized, 9,238,000 and 18,610,000 shares issued and
    outstanding, respectively...............................        93           186
  Class B Common Stock, $.01 par value, 22,000,000 shares
    authorized, 7,510,000 and 15,020,000 shares issued and
    outstanding, respectively...............................        75           150
  Additional paid-in capital................................   106,901       110,099
  Accumulated other comprehensive income....................       (27)          (74)
  Retained earnings.........................................   103,648       146,322
                                                              --------    ----------
                                                               210,690       256,683
  Class A Common Stock in treasury at cost, 475,000
    shares..................................................    (6,989)       (6,989)
                                                              --------    ----------
    Total stockholders' equity..............................   203,701       249,694
                                                              --------    ----------
    Total liabilities and stockholders' equity..............  $402,508    $1,095,461
                                                              ========    ==========
</TABLE>
    
 
See accompanying Notes to Consolidated Financial Statements.
 
                                       F-4
<PAGE>   76
 
                             EXPRESS SCRIPTS, INC.
 
                      CONSOLIDATED STATEMENT OF OPERATIONS
 
   
<TABLE>
<CAPTION>
                                                     YEAR ENDED DECEMBER 31,
                                             ---------------------------------------
                                               1996          1997           1998
                                             ---------    -----------    -----------
                                              (IN THOUSANDS, EXCEPT PER SHARE DATA)
<S>                                          <C>          <C>            <C>
Net revenues (including $152,311, $208,118
  and $145,758, respectively, from related
  parties).................................  $773,615     $1,230,634     $2,824,872
                                             --------     ----------     ----------
Cost and expenses:
  Cost of revenues (including $7,636,
     $11,690 and $7,257, respectively, to
     related parties)......................   684,882      1,119,167      2,584,997
  Selling, general and administrative......    49,103         62,617        148,990
  Corporate restructuring..................        --             --          1,651
                                             --------     ----------     ----------
                                              733,985      1,181,784      2,735,638
                                             --------     ----------     ----------
Operating income...........................    39,630         48,850         89,234
                                             --------     ----------     ----------
Interest income (expense):
  Interest income..........................     3,509          6,081          7,236
  Interest expense.........................       (59)          (225)       (20,230)
                                             --------     ----------     ----------
                                                3,450          5,856        (12,994)
                                             --------     ----------     ----------
Income before income taxes.................    43,080         54,706         76,240
Provision for income taxes.................    16,932         21,277         33,566
                                             --------     ----------     ----------
Net income.................................  $ 26,148     $   33,429     $   42,674
                                             ========     ==========     ==========
Basic earnings per share...................  $   0.81     $     1.02     $     1.29
                                             ========     ==========     ==========
Weighted average number of common shares
  outstanding during the period -- Basic
  EPS......................................    32,160         32,713         33,105
                                             ========     ==========     ==========
Diluted earnings per share.................  $   0.80     $     1.01     $     1.27
                                             ========     ==========     ==========
Weighted average number of common shares
  outstanding during the period -- Diluted
  EPS......................................    32,700         33,122         33,698
                                             ========     ==========     ==========
</TABLE>
    
 
   
See accompanying Notes to Consolidated Financial Statements.
    
 
                                       F-5
<PAGE>   77
 
                             EXPRESS SCRIPTS, INC.
 
           CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY
 
<TABLE>
<CAPTION>
                              NUMBER OF SHARES                                        AMOUNT
                              -----------------   -------------------------------------------------------------------------------
                                                                                    ACCUMULATED
                              CLASS A   CLASS B   CLASS A   CLASS B   ADDITIONAL       OTHER
                              COMMON    COMMON    COMMON    COMMON     PAID-IN     COMPREHENSIVE   RETAINED   TREASURY
                               STOCK     STOCK     STOCK     STOCK     CAPITAL        INCOME       EARNINGS    STOCK      TOTAL
                              -------   -------   -------   -------   ----------   -------------   --------   --------   --------
                                                                        (IN THOUSANDS)
<S>                           <C>       <C>       <C>       <C>       <C>          <C>             <C>        <C>        <C>
Balance at December 31,
  1995......................   4,539    10,500    $   45     $105      $ 33,158        $  --       $ 44,071   $    --    $ 77,379
  Comprehensive income:
    Net income..............                                                                         26,148                26,148
    Other comprehensive
      income,
      Foreign currency
         translation
         adjustment.........      --        --        --       --            --           (2)            --        --          (2)
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
  Comprehensive income......      --        --        --       --            --           (2)        26,148        --      26,146
  Conversion of Class B
    Common Stock to Class A
    Common Stock............   2,990    (2,990)       30      (30)
  Issuance of Class A Common
    Stock
      Contractual
         agreement..........     227                   2                 11,250                                            11,252
      Public offering.......   1,150                  12                 52,580                                            52,592
  Exercise of stock
    options.................      68                   1                  1,309                                             1,310
  Tax benefit relating to
    employee stock
    options.................                                                661                                               661
  Treasury Stock acquired...      --        --        --       --            --           --             --    (5,250)     (5,250)
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
Balance at December 31,
  1996......................   8,974     7,510        90       75        98,958           (2)        70,219    (5,250)    164,090
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
  Comprehensive income:
    Net income..............                                                                         33,429                33,429
    Other comprehensive
      income,
      Foreign currency
         translation
         adjustment.........      --        --        --       --            --          (25)            --        --         (25)
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
  Comprehensive income......      --        --        --       --            --          (25)        33,429        --      33,404
  Exercise of stock
    options.................     264                   3                  4,769                                             4,772
  Tax benefit relating to
    employee stock
    options.................                                              3,174                                             3,174
  Treasury Stock acquired...      --        --        --       --            --           --             --    (1,739)     (1,739)
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
Balance at December 31,
  1997......................   9,238     7,510        93       75       106,901          (27)       103,648    (6,989)    203,701
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
  Comprehensive income:
    Net income..............                                                                         42,674                42,674
    Other comprehensive
      income,
      Foreign currency
         translation
         adjustment.........      --        --        --       --            --          (47)            --        --         (47)
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
  Comprehensive income......      --        --        --       --            --          (47)        42,674        --      42,627
  Issuance of stock
    dividend................   9,239     7,510        92       75          (167)
  Exercise of stock
    options.................     133                   1                  2,020                                             2,021
  Tax benefit relating to
    employee stock
    options.................      --        --        --       --         1,345           --             --        --       1,345
                              ------    ------    ------     ----      --------        -----       --------   -------    --------
Balance at December 31,
  1998......................  18,610    15,020    $  186     $150      $110,099        $ (74)      $146,322   $(6,989)   $249,694
                              ======    ======    ======     ====      ========        =====       ========   =======    ========
</TABLE>
 
   
See accompanying Notes to Consolidated Financial Statements.
    
 
                                       F-6
<PAGE>   78
 
                             EXPRESS SCRIPTS, INC.
 
                      CONSOLIDATED STATEMENT OF CASH FLOWS
 
<TABLE>
<CAPTION>
                                                    YEAR ENDED DECEMBER 31,
                                               ---------------------------------
                                                 1996        1997        1998
                                               --------    --------    ---------
                                                        (IN THOUSANDS)
<S>                                            <C>         <C>         <C>
Cash flows from operating activities:
  Net income.................................  $ 26,148    $ 33,429    $  42,674
  Adjustments to reconcile net income to net
     cash provided by operating activities:
     Depreciation and amortization...........     6,707      10,470       27,042
     Deferred income taxes...................       317        (834)      10,068
     Bad debt expense........................     1,456       3,680        4,583
     Corporate restructuring, less cash
       payments of $184......................                              1,467
     Tax benefit relating to employee stock
       options...............................       661       3,174        1,345
     Changes in operating assets and
       liabilities, net of changes resulting
       from acquisition:
       Receivables...........................   (48,149)    (50,166)     (35,083)
       Inventories...........................    (3,638)    (11,444)     (15,417)
       Prepaid expenses and other assets.....    (3,104)      1,722          756
       Claims and rebates payable............    41,055      57,968      107,660
       Accounts payable and accrued
          expenses...........................     8,410       4,504      (18,521)
                                               --------    --------    ---------
Net cash provided by operating activities....    29,863      52,503      126,574
                                               --------    --------    ---------
Cash flows from investing activities:
  Acquisitions, net of cash acquired.........      (940)                (460,137)
  Short-term investments.....................   (54,388)     (3,550)      57,938
  Purchases of property and equipment........    (9,480)    (13,017)     (23,853)
                                               --------    --------    ---------
Net cash (used in) investing activities......   (64,808)    (16,567)    (426,052)
                                               --------    --------    ---------
Cash flows from financing activities:
  Proceeds on long-term debt.................        --          --      360,000
  Proceeds from stock offering...............    52,592
  Deferred financing fees....................                             (4,062)
  Acquisition of treasury stock..............    (5,250)     (1,739)
  Exercise of stock options..................     1,310       4,772        2,021
                                               --------    --------    ---------
Net cash provided by financing activities....    48,652       3,033      357,959
                                               --------    --------    ---------
Effect of foreign currency translation
  adjustment.................................        (2)        (25)         (47)
                                               --------    --------    ---------
Net increase in cash and cash equivalents....    13,705      38,944       58,434
Cash and cash equivalents at beginning of
  year.......................................    11,506      25,211       64,155
                                               --------    --------    ---------
Cash and cash equivalents at end of year.....  $ 25,211    $ 64,155    $ 122,589
                                               ========    ========    =========
Supplemental data:
Cash paid during the year for:
  Income taxes...............................  $ 14,544    $ 20,691    $  17,202
  Interest...................................  $     59    $    225    $  13,568
</TABLE>
 
   
See accompanying Notes to Consolidated Financial Statements.
    
 
                                       F-7
<PAGE>   79
 
                             EXPRESS SCRIPTS, INC.
 
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
 
1.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
 
   
     ORGANIZATION AND OPERATIONS.  Express Scripts, Inc. ("the Company") is a
leading specialty managed care company and (subsequent to its acquisition of
Value Health, Inc. and Managed Prescription Network, Inc. on April 1, 1998, see
Note 2) is the largest full-service pharmacy benefit management ("PBM") company
independent of pharmaceutical manufacturer ownership and drug store ownership in
North America. The Company provides healthcare management and administration
services on behalf of thousands of clients that include health maintenance
organizations, health insurers, third-party administrators, employers and
union-sponsored benefit plans. The Company's fully-integrated PBM services
include network claims processing, mail pharmacy services, benefit design
consultation, drug utilization review, formulary management, disease management,
medical and drug data analysis services, medical information management
services, which include provider profiling and outcome assessments through its
majority-owned Practice Patterns Science, Inc. ("PPS") subsidiary, and informed
decision counseling services through its Express Health LineSM division. The
Company also provides non-PBM services which include infusion therapy services
through its wholly-owned subsidiary IVTx, Inc. ("IVTx"), distribution services
through its Specialty Distribution division, and, prior to September 1, 1998,
provided managed vision care programs through its wholly-owned subsidiary
Express Scripts Vision Corporation ("Vision").
    
 
     In March 1992, the Company, originally incorporated in Missouri in 1986,
was reincorporated in Delaware and issued an aggregate of 21,000,000 shares of
Class B Common Stock to Sanus Corp. Health Systems ("Sanus") in exchange for the
outstanding shares of its common stock. Sanus at that time was an indirect
subsidiary of New York Life Insurance Company ("NYL"). In April 1992, as a
result of a reorganization, both the Company and Sanus became direct
subsidiaries of NYLIFE HealthCare Management, Inc. ("NYLIFE"). Sanus has since
changed its name to NYLCare Health Plans, Inc. ("NYLCare"). In April 1996,
NYLIFE converted 5,980,000 Class B shares to Class A Common Stock and sold those
shares in a public offering. NYLIFE continues to own all the remaining
outstanding Class B Common Stock of the Company (see Note 11).
 
     BASIS OF PRESENTATION.  The consolidated financial statements include the
accounts of the Company and all wholly-owned and majority-owned subsidiaries.
All significant intercompany accounts and transactions have been eliminated.
Certain amounts in prior years have been reclassified to conform with 1998
classifications. The preparation of the consolidated financial statements
conform to generally accepted accounting principles, and require management to
make estimates and assumptions that affect the reported amounts of assets and
liabilities at the date of the financial statements and the reported amounts of
revenues and expenses during the reporting period. Actual amounts could differ
from those estimates and assumptions.
 
     CASH AND CASH EQUIVALENTS.  Cash and cash equivalents include cash on hand
and temporary investments in money market funds.
 
     SHORT-TERM INVESTMENTS.  Short-term investments consisted of debt
securities with a maturity of less than one year that the Company had the
positive intent and ability to hold to maturity and are reported at amortized
cost.
 
                                       F-8
<PAGE>   80
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     INVENTORIES.  Inventories consist of prescription drugs, vision supplies
and medical supplies that are stated at the lower of first-in first-out cost or
market.
 
     PROPERTY AND EQUIPMENT.  Property and equipment is carried at cost and is
depreciated using the straight-line method over estimated useful lives of seven
years for furniture, five years for equipment and purchased computer software
and three years for personal computers. Leasehold improvements are amortized on
a straight-line basis over the term of the lease or the useful life of the
asset, if shorter. Expenditures for repairs, maintenance and renewals are
charged to income as incurred. Expenditures which improve an asset or extend its
estimated useful life are capitalized. When properties are retired or otherwise
disposed of, the related cost and accumulated depreciation are removed from the
accounts and any gain or loss is included in income.
 
   
     SOFTWARE DEVELOPMENT COSTS.  During 1997, the Company early adopted
Statement of Position No. 98-1 ("SOP 98-1"), Accounting for the Costs of
Computer Software Developed or Obtained for Internal Use. SOP 98-1 requires the
capitalization of certain costs associated with computer software developed or
obtained for internal use. Given the limited software developed or obtained for
internal use in 1997, adoption had virtually no effect on the Company's
Consolidated Statement of Operations or its financial position. However, the
impact of SOP 98-1 on an ongoing basis will be determined by the magnitude of
computer software developed or obtained for internal use. Research and
development expenditures relating to the development of software to be marketed
to clients, or to be used for internal purposes, are charged to expense until
technological feasibility is established. Thereafter, the remaining software
production costs up to the date of general release to customers, or to the date
placed into production, are capitalized and included as Property and Equipment.
During 1996, 1997 and 1998, $1,898,000, $1,982,000 and $10,244,000 in software
development costs were capitalized, respectively. Capitalized software
development costs amounted to $5,269,000 and $27,516,000 at December 31, 1997
and 1998, respectively. Amortization of the capitalized amounts commences on the
date of general release to customers, or the date placed into production, and is
computed on a product-by-product basis using the straight-line method over the
remaining estimated economic life of the product but not more than five years.
Reductions, if any, in the carrying value of capitalized software costs to net
realizable value are also included in amortization expense. Amortization expense
in 1996, 1997 and 1998 was $136,000, $622,000 and $1,968,000, respectively.
    
 
     GOODWILL.  Goodwill is amortized on a straight-line basis over periods from
15 to 30 years. The amount reported is net of accumulated amortization of
$251,000 and $8,114,000 at December 31, 1997 and 1998, respectively. The Company
periodically evaluates the carrying value of goodwill for impairment. The
evaluation of impairment is based on expected future operating cash flows on an
undiscounted basis for the operations to which goodwill relates. Impairment
losses, if any, would be determined based on the present value of the cash flows
using discount rates that reflect the inherent risk of the underlying business.
In the opinion of management, no such impairment existed at December 31, 1997 or
1998. Amortization expense, included in selling, general and administrative
expenses, was $42,000, $42,000 and $7,863,000 for the years ended December 31,
1996, 1997 and 1998, respectively.
 
                                       F-9
<PAGE>   81
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     OTHER INTANGIBLE ASSETS.  Other intangible assets (included in other
assets) consist of customer contracts, non-compete agreements and deferred
financing fees and are amortized on a straight-line basis over periods from 2 to
20 years. Amortization expense for customer contracts and non-compete
agreements, included in selling, general and administrative expenses, and for
deferred financing fees, included in interest expense, was $4,320,000 and
$609,000, respectively, for the year ended December 31, 1998.
 
     CONTRACTUAL AGREEMENTS.  The Company has entered into corporate alliances
with certain of its clients whereby shares of the Company's Class A Common Stock
were awarded as advance discounts to the clients. The Company accounts for these
agreements as follows:
 
          PRIOR TO DECEMBER 15, 1995 -- For agreements consummated prior to
     December 15, 1995, the stock is valued utilizing the quoted market value at
     the date the agreement is consummated if the number of shares to be issued
     is known. If the number of shares to be issued is contingent upon the
     occurrence of future events, the stock is valued utilizing the quoted
     market value at the date the contingency is satisfied and the number of
     shares is determinable.
 
          BETWEEN DECEMBER 15, 1995 AND NOVEMBER 20, 1997 -- For agreements
     entered into between these dates, the Company utilizes the provisions of
     Financial Accounting Standards Board Statement 123 "Accounting for
     Stock-Based Compensations" ("FAS 123") which requires that all stock issued
     to nonemployees be accounted for based on the fair value of the
     consideration received or the fair value of the equity instruments issued
     instead of the intrinsic value method utilized for stock issued or to be
     issued under alliances entered into prior to December 15, 1995. The Company
     has adopted FAS 123 as it relates to stock issued or to be issued under the
     Premier and Manulife alliances based on fair value at the date the
     agreement was consummated.
 
          SUBSEQUENT TO NOVEMBER 20, 1997 -- In November 1997, the Emerging
     Issues Task Force reached a consensus that the value of equity instruments
     issued for consideration other than employee services should be initially
     determined on the date on which a "firm commitment" for performance first
     exists by the provider of goods or services. Firm commitment is defined as
     a commitment pursuant to which performance by a provider of goods or
     services is probable because of sufficiently large disincentives for
     nonperformance. The consensus must be applied for all new arrangements and
     modifications of existing arrangements entered into from November 20, 1997.
     The consensus only addresses the date upon which fair value is determined
     and does not change the accounting based upon fair value as prescribed by
     FAS 123. No such arrangements have been entered into by the Company
     subsequent to November 20, 1997.
 
     Shares issued on the effective date of the contractual agreement are
     considered outstanding and included in basic and diluted earnings per share
     computations when issued. Shares issuable upon the satisfaction of certain
     conditions are considered outstanding and included in basic and dilutive
     earnings per share computation when all necessary conditions have been
     satisfied by the end of the period. If all necessary conditions have not
     been satisfied by the end of the period, the number of shares included in
     the dilutive earnings per share computation is based on the number of
 
                                      F-10
<PAGE>   82
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     shares, if any, that would be issuable if the end of the reporting period
     were the end of the contingency period and if the result would be dilutive.
     The value of the shares of stock awarded as advance discounts is recorded
     as a deferred cost and included in other assets. The deferred cost is
     recognized in selling, general and administrative expenses over the period
     of the contract.
 
   
     IMPAIRMENT OF LONG LIVED ASSETS.  The Company evaluates whether events and
circumstances have occurred that indicate the remaining estimated useful life of
long lived assets may warrant revision or that the remaining balance of an asset
may not be recoverable. The measurement of possible impairment is based on the
ability to recover the balance of assets from expected future operating cash
flows on an undiscounted basis. Impairment losses, if any, would be determined
based on the present value of the cash flows using discount rates that reflect
the inherent risk of the underlying business. In the opinion of management, no
such impairment existed as of December 31, 1997 or 1998, except for the
write-down of the long-lived assets of Express Scripts Vision Corporation (see
Note 7).
    
 
     DERIVATIVE FINANCIAL INSTRUMENTS.  The Company has entered into an interest
rate swap agreement in order to manage exposure to interest rate risk. The
Company does not hold or issue derivative financial instruments for trading
purposes. The interest rate swap is designated as a hedge of the Company's
variable interest rate payments. Amounts received or paid are accrued as
interest receivable or payable and as interest income or expense. The fair value
of interest rate swap agreements is based on market prices. The fair value
represents the estimated amount the Company would receive/pay to terminate the
agreements taking into consideration current interest rates.
 
     In June 1998, the Financial Accounting Standards Board ("the FASB") issued
Statement of Financial Accounting Standards No. 133, "Accounting for Derivative
Instruments and Hedging Activities" ("FAS 133"). The Statement requires all
derivatives be recognized as either assets or liabilities in the statement of
financial position and measure those instruments at fair value. In addition, the
Statement specifies the accounting for changes in the fair value of a derivative
based on the intended use of the derivative and the resulting designation. FAS
133 is effective for all fiscal quarters of fiscal years beginning after June
15, 1999 and will be applicable to the Company's first quarter of fiscal year
2000. The Company's present interest rate swap (see Note 6) would be considered
a cash flow hedge. Accordingly, the change in the fair value of the swap would
be reported on the balance sheet as an asset or liability. The corresponding
unrealized gain or loss representing the effective portion of the hedge will be
initially recognized in stockholders' equity and other comprehensive income, and
subsequently any changes in unrealized gain or loss from the initial measurement
date will be recognized in earnings concurrent with the interest expense on the
Company's underlying variable rate debt. If the Company had adopted FAS 133 as
of December 31, 1998, the Company would record the unrealized loss of $7,209,000
as a liability and reduction in stockholder's equity and other comprehensive
income.
 
     FAIR VALUE OF FINANCIAL INSTRUMENTS.  The carrying value of cash and cash
equivalents, short-term investments, accounts receivable and accounts payable
approximated fair values due to the short-term maturities of these instruments.
The fair value, which approximates the carrying value, of the Company's term
loan facility was estimated using either quoted
 
                                      F-11
<PAGE>   83
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
market prices or the current rates offered to the Company for debt with similar
maturity. The fair value of the swap ($7,209,000 liability at December 31, 1998)
was based on quoted market price, which reflects the present value of the
difference between estimated future fixed rate payments and future variable rate
receipts.
 
     REVENUE RECOGNITION.  Revenues from dispensing prescription and
non-prescription medical products from the Company's mail service pharmacies are
recorded upon shipment. Revenue from sales of prescription drugs by pharmacies
in the Company's nationwide network and pharmacy claims processing revenues are
recognized when the claims are processed. When the Company dispenses
pharmaceuticals to members of health benefit plans sponsored by the Company's
clients or has an independent contractual obligation to pay its network pharmacy
providers for benefits provided to members of its clients' pharmacy benefit
plans, the Company includes payments from plan sponsors for these benefits as
net revenue and ingredient costs or payments to these pharmacy providers in cost
of revenues. If the Company is only administering the plan sponsors' network
pharmacy contracts, or where the Company dispenses pharmaceuticals supplied by
one of the Company's clients, the Company records only the administrative or
dispensing fees derived from the Company's contracts with the plan sponsors as
net revenue.
 
   
     Client revenue is recognized based upon actual scripts adjudicated and
therefore requires no estimation. Amounts remain unbilled for no more than 30
days based upon the contractual billing schedule agreed with the client.
    
 
   
     COST OF REVENUES.  Cost of revenues includes product costs, pharmacy claims
payments and other direct costs associated with dispensing prescriptions and
non-prescription medical products and claims processing operations, offset by
fees received from pharmaceutical manufacturers in connection with the Company's
drug purchasing and formulary management programs. The Company estimates fees
receivable from pharmaceutical manufacturers on a quarterly basis converting
total prescriptions dispensed to estimated rebatable scripts (i.e., those
prescriptions with respect to which the Company is contractually entitled to
submit claims for rebates) multiplied by the contractually agreed manufacturer
rebate amount. Estimates are revised once the actual rebatable scripts are
calculated and rebates are billed to the manufacturer.
    
 
     INCOME TAXES.  Deferred tax assets and liabilities are recognized based on
temporary differences between financial statement basis and tax basis of assets
and liabilities using presently enacted tax rates.
 
     EARNINGS PER SHARE.  Basic earnings per share is computed using the
weighted average number of common shares outstanding during the period. Diluted
earnings per share is computed in the same manner as basic earnings per share
but adds the number of additional common shares that would have been outstanding
for the period if the dilutive potential common shares had been issued. The only
difference between the number of weighted average shares used in the basic and
diluted calculation for all years is stock options and stock warrants granted by
the Company using the "treasury stock" method, amounting to 540,000, 409,000 and
593,000 in 1996, 1997 and 1998, respectively.
 
     FOREIGN CURRENCY TRANSLATION.  The financial statements of ESI Canada, Inc.
are translated into U.S. Dollars using the exchange rate at each balance sheet
date for assets and liabilities and a weighted average exchange rate for each
period for revenues, expenses,
 
                                      F-12
<PAGE>   84
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
gains and losses. The functional currency for ESI Canada, Inc. is the local
currency and translation adjustments are recorded within the other comprehensive
income component of stockholders' equity.
 
     EMPLOYEE STOCK-BASED COMPENSATION.  The Company accounts for employee stock
options in accordance with Accounting Principles Board No. 25 ("APB 25"),
"Accounting for Stock Issued to Employees." Under APB 25, the Company applies
the intrinsic value method of accounting and, therefore, does not recognize
compensation expense for options granted, because options are only granted at a
price equal to market value at the time of grant. During 1996, FAS 123 became
effective for the Company. FAS 123 prescribes the recognition of compensation
expense based on the fair value of options determined on the grant date.
However, FAS 123 grants an exception that allows companies currently applying
APB 25 to continue using that method. The Company has, therefore, elected to
continue applying the intrinsic value method under APB 25. For companies that
choose to continue applying the intrinsic value method, FAS 123 mandates certain
pro forma disclosures as if the fair value method had been utilized (see Note
12).
 
     COMPREHENSIVE INCOME.  During 1998, Statement of Financial Accounting
Standards No. 130 ("FAS 130"), "Reporting Comprehensive Income," became
effective for the Company. FAS 130 requires noncash changes in stockholders'
equity be combined with net income and reported in a new financial statement
category entitled "comprehensive income." Other than net income, the only
component of comprehensive income for the Company is the change in the foreign
currency translation adjustment. The Company has displayed comprehensive income
within the Statement of Changes in Stockholders' Equity.
 
     SEGMENT REPORTING.  In June 1997, the FASB issued Statement of Financial
Accounting Standards No. 131, "Disclosures about Segments of an Enterprise and
Related Information" ("FAS 131"). FAS 131 requires that the Company report
certain information, if specific requirements are met, about operating segments
of the Company including information about services, geographic areas of
operation and major customers. The information is to be derived from the
management approach which designates the internal organization that is used by
management for making operating decisions and assessing performance as the
source of the Company's reportable segments. Adoption of FAS 131 did not affect
the Company's results of operations or its financial position but did affect the
disclosure of segment information (see Note 13).
 
2.  ACQUISITION
 
     On April 1, 1998 the Company acquired all of the outstanding capital stock
of Value Health, Inc. and Managed Prescriptions Network, Inc. (collectively, the
"Acquired Entities") from Columbia/HCA Healthcare Corporation ("Columbia") for
approximately $460 million in cash (which includes transactions costs and
executive management severance costs of approximately $15 million),
approximately $360 million of which was obtained through a five-year bank credit
facility (see Note 6) and the remainder from the Company's cash balances and
short term investments. At closing, the Acquired Entities owned various
subsidiaries that now or formerly conducted a PBM business, commonly known as
"ValueRx".
 
                                      F-13
<PAGE>   85
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     The acquisition has been accounted for using the purchase method of
accounting and the results of operations of the Acquired Entities have been
included in the consolidated financial statements and PBM segment since April 1,
1998. The purchase price has been preliminarily allocated based on the estimated
fair values of net assets acquired at the date of the acquisition. The excess of
purchase price over tangible net assets acquired was originally allocated to
other intangible assets consisting of customer contracts and non-compete
agreements in the amount of $57,653,000 which are being amortized using the
straight-line method over the estimated useful lives of 2 to 20 years and are
included in other assets, and goodwill in the amount of $289,863,000 which is
being amortized using the straight-line method over the estimated useful life of
30 years. In conjunction with the acquisition, the Acquired Entities and their
subsidiaries retained the following liabilities:
 
<TABLE>
<CAPTION>
                                                           (IN THOUSANDS)
<S>                                                        <C>
Fair value of assets acquired............................    $ 656,488
Cash paid for the capital stock..........................     (460,137)
                                                             ---------
     Liabilities retained................................    $ 196,351
                                                             =========
</TABLE>
 
     The following unaudited pro forma information presents a summary of
combined results of operations of the Company and the Acquired Entities as if
the acquisition had occurred at the beginning of the period presented, along
with certain pro forma adjustments to give effect to amortization of goodwill,
other intangible assets, interest expense on acquisition debt and other
adjustments. The pro forma financial information is not necessarily indicative
of the results of operations as they would have been had the transaction been
effected on the assumed dates. Included in the pro forma information are
integration costs incurred by the Company that are being reported within
selling, general and administrative expenses in the statement of operations.
 
<TABLE>
<CAPTION>
                                                YEAR ENDED DECEMBER 31,
                                                ------------------------
                                                   1997          1998
                                                ----------    ----------
                                                (IN THOUSANDS EXCEPT PER
                                                      SHARE DATA)
<S>                                             <C>           <C>
Net revenues..................................  $2,877,906    $3,234,800
Net income....................................      33,687        42,696
Basic earnings per share......................        1.03          1.29
Diluted earnings per share....................        1.02          1.27
</TABLE>
 
3.  CONTRACTUAL AGREEMENTS
 
     On December 31, 1995, the Company entered into a ten-year corporate
alliance with Premier Purchasing Partners, L.P. (formerly, American Healthcare
Systems Purchasing Partners, L.P., the "Partnership"), an affiliate of Premier,
Inc. ("Premier"). Premier is an alliance of healthcare systems resulting from
the merger in 1995 of American Healthcare Systems, Premier Health Alliance and
SunHealth Alliance. Under the terms of the transaction, the Company is Premier's
preferred vendor of pharmacy benefit management services to Premier's
shareholder systems and their managed care affiliates and will issue shares of
its Class A Common Stock as an administrative fee to the Partnership based on
 
                                      F-14
<PAGE>   86
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
   
the attainment of certain benchmarks, principally related to the number of
members receiving the Company's pharmacy benefit management services under the
arrangement, and to the achievement of certain joint purchasing goals. The
Company may be required to issue up to 4,500,000 shares to the Partnership over
a period up to the first five years of the agreement if the Partnership exceeds
all benchmarks. Except for certain exemptions from registration under the
Securities Act of 1933 ("the 1933 Act"), any shares issued to the Partnership
cannot be traded until they have been registered under the 1933 Act and any
applicable state securities laws.
    
 
   
     In accordance with the terms of the agreement, the Company issued 454,546
shares of Class A Stock to Premier in May, 1996. The shares were valued at
$11,250,000 using the Company's closing stock price on December 31, 1995, the
date the agreement was consummated, and are being amortized over the remaining
term of the agreement. Amortization expense in 1996, 1997 and 1998 was $776,000,
$1,164,000 and $1,164,000, respectively. No additional shares have been earned
by Premier through December 31, 1998.
    
 
     Effective January 1, 1996, the Company executed a multi-year contract with
The Manufacturers Life Insurance Company ("Manulife"), to introduce pharmacy
benefit management services in Canada. Manulife's Group Benefits Division
continues to work with ESI Canada to provide these services. Under the terms of
the agreement, the Company is the exclusive third-party provider of pharmacy
benefit management services to Manulife's Canadian clients. The Company also
will issue shares of its Class A Common Stock as an advance discount to Manulife
based upon achievement of certain volumes of Manulife pharmacy claims processed
by the Company. No shares will be issued until after the fourth year of the
agreement based on volumes reached in years two through four. The Company
anticipates issuing no more than 474,000 shares to Manulife over a period up to
the first six years of the agreement. Except for certain exemptions from
registration under the 1933 Act, any shares issued to Manulife cannot be traded
until they have been registered under the 1933 Act and any applicable state
securities laws. In accordance with the terms of the agreement, no stock has
been issued since inception.
 
     If Manulife has not exercised an early termination option at the end of the
sixth or tenth year of the agreement, the Company will issue at each of those
times a ten-year warrant as an advance discount to purchase up to approximately
237,000 additional shares of the Company's Class A Common Stock exercisable at
85% of the market price at those times. The actual number of shares for which
such warrant is to be issued is based on the volume of Manulife pharmacy claims
processed by the Company in year six and year ten, respectively.
 
     Pursuant to an agreement with Coventry Corporation, an operator of health
maintenance organizations located principally in Pennsylvania and Missouri, on
January 3, 1995, the Company issued 50,000 shares of Class A Common Stock as an
advance discount to Coventry in a private placement. These shares were valued at
$13.69 per share, the split-adjusted per share market value of the Company's
Class A Common Stock on November 22, 1994, which was the date the agreement was
consummated and the obligation of the parties became unconditional. No revision
of the consideration for the transaction occurred between November 22, 1994 and
January 3, 1995. The shares issued to Coventry were being amortized over a
six-year period. However, due to Coventry
 
                                      F-15
<PAGE>   87
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
   
extending the agreement for only two years, as discussed below, instead of three
years, the estimated useful life of the shares issued has been reduced to five
years. Amortization expense was $114,000, $114,000 and $171,000 for each of the
years ended December 31, 1996, 1997 and 1998, respectively. Except for certain
exemptions from registration under the 1933 Act, these shares cannot be traded
until they have been registered under the 1933 Act and any applicable state
securities laws.
    
 
     Effective January 1, 1998, Coventry renewed the agreement for a two-year
term through December 31, 1999. As part of the agreement, the Company issued
warrants as an advance discount to purchase an additional 50,000 shares of the
Company's Class A Common Stock, exercisable at 90% of the market value at the
time of renewal. During 1998, the Company expensed the advance discount which
represented 10% of the market value.
 
     On October 13, 1992, the Company entered into a five-year arrangement with
FHP, Inc. ("FHP") pursuant to which the Company agreed to provide pharmacy
benefit services to FHP and its members. FHP is an operator of health
maintenance organizations, principally in the western United States. In February
1997, PacifiCare Health Systems, Inc. ("PacifiCare") completed the acquisition
of FHP. As a result of the merger, PacifiCare informed the Company that it would
not enter into a long-term extension of the agreement and reached an agreement
with the Company to phase-out membership starting in July 1997 and continued
through March 1998.
 
     In accordance with the agreement, the Company commenced providing pharmacy
benefit services to FHP and its members on January 4, 1993. On the commencement
date and pursuant to the agreement, the Company issued 400,000 shares of its
Class A Common Stock as advance discounts to FHP in a private placement. These
shares were valued at $4.13 per share, the split-adjusted per share market value
of the Company's Class A shares on October 13, 1992, which was the date the
agreement was consummated and the obligations of the parties became
unconditional. No revision of the consideration for the transaction occurred
between October 13, 1992 and January 4, 1993. The cost of the shares issued to
FHP was amortized over a five-year period ending in 1997. No amortization
expense was recorded in 1998. Amortization expense was $165,000 in 1996 and
$990,000 in 1997.
 
4.  RELATED PARTY TRANSACTIONS
 
     The Company had agreements to provide claims processing services and mail
pharmacy prescription services for NYLCare, in return for which it receives
processing fees and reimbursement for the contracted cost of the claims.
Effective July 15, 1998, NYL consummated the sale of NYLCare to Aetna U.S.
Healthcare, Inc., an unrelated party. Therefore, related party amounts for 1998
represent only the period in which NYL owned NYLCare. Transactions subsequent to
July 15, 1998 have been included in unrelated parties. Cost of revenues from
related parties were $122,157,000, $176,761,000 and $127,255,000 in 1996, 1997
and 1998, respectively.
 
                                      F-16
<PAGE>   88
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     The amount receivable from or (due to) related parties comprised the
following:
 
<TABLE>
<CAPTION>
                                                               DECEMBER 31,
                                                                   1997
                                                              --------------
                                                              (IN THOUSANDS)
<S>                                                           <C>
     Receivable from NYLCare................................     $23,709
     Due to NYLCare.........................................      (7,479)
                                                                 -------
     Total related party receivable.........................     $16,230
                                                                 =======
</TABLE>
 
     Prior to July 15, 1998, the Company was the exclusive provider of pharmacy
benefit management services to NYLCare's managed healthcare subsidiaries,
subject to certain exceptions. The Company's agreement with NYLCare provided
that fees from drug manufacturers whose products are used in the Company's
formularies related to NYLCare subsidiaries was allocated 100% to the Company up
to $400,000 and 75% to NYLCare and 25% to the Company thereafter. The Company
was also the non-exclusive provider of pharmacy benefit management services to
New York Life and Health Insurance Company ("NYLHIC"), a subsidiary of NYLCare.
In 1996 fees from drug manufacturers with respect to this business were
allocated 100% to the Company. Effective January 1, 1997, the Company shared
such fees with NYLHIC on a fixed per script amount which approximates 40% of the
total of such fees.
 
     Such fees allocated to NYLCare and NYLHIC were $7,636,000, $11,690,000 and
$7,257,000 in 1996, 1997 and 1998, respectively, and $3,064,000 in 1996,
$5,803,000 in 1997 and $2,307,000 in 1998 were allocated to the Company and have
been classified in the accompanying consolidated statement of operations as a
reduction of cost of revenues.
 
     As discussed in Note 3, the Company has entered into a ten year corporate
alliance with Premier. Richard Norling is the Chief Operating Officer of Premier
and a member of the Company's Board of Directors. No consideration, monetary or
otherwise, has been exchanged between the Company and Premier between the period
September 1997 and December 1998 (the period during which Premier and the
Company are related parties). The Company may be required to issue additional
shares of its Class A Common Stock to Premier as discussed in Note 3.
 
     Premier is required to promote the Company as the preferred PBM provider to
healthcare entities, plans and facilities which participate in Premier's
purchasing programs. However, all contractual arrangements to provide services
are made directly between the Company and these entities, at varying terms and
independent of any Premier involvement. Therefore, the associated revenues
earned and expenses incurred by the Company are not deemed to be related party
transactions. During 1998, the net revenues that the Company derived from
services provided to the healthcare entities participating in Premier's
purchasing programs was $78,539,000.
 
                                      F-17
<PAGE>   89
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
5.  PROPERTY AND EQUIPMENT
 
     Property and equipment, at cost, consists of the following:
 
<TABLE>
<CAPTION>
                                                      DECEMBER 31,
                                                   -------------------
                                                    1997        1998
                                                   -------    --------
                                                     (IN THOUSANDS)
<S>                                                <C>        <C>
Land.............................................  $    --    $  2,051
Building.........................................                3,076
Furniture........................................    4,362       8,336
Equipment........................................   28,924      52,758
Computer software................................   12,011      37,412
Leasehold improvements...........................    3,934       8,275
                                                   -------    --------
                                                    49,231     111,908
Less accumulated depreciation and amortization...   22,410      34,409
                                                   -------    --------
                                                   $26,821    $ 77,499
                                                   =======    ========
</TABLE>
 
6.  FINANCING
 
     On April 1, 1998, the Company executed a $440 million credit facility with
a bank syndicate led by Bankers Trust Company, consisting of a $360 million term
loan facility and an $80 million revolving loan facility. The credit facility
expires on April 15, 2003 and is guaranteed by the Company's domestic
subsidiaries other than Practice Patterns Science, Inc. ("PPS"), and Great
Plains Reinsurance Company ("Great Plains") and secured by pledges of 100% (or,
in the case of foreign subsidiaries, 65%) of the capital stock of the Company's
subsidiaries other than PPS and Great Plains. The provisions of this loan
require quarterly interest payments and, beginning in April 1999, semi-annual
principal payments. The interest rate is based on a spread ("Credit Rate
Spread") over several London Interbank Offered Rates ("LIBOR") or base rate
options, depending upon the Company's ratio of earnings before interest, taxes,
depreciation and amortization to debt ("Leverage Ratio"). At December 31, 1998,
the interest rate was 6.0625%, representing a credit rate spread of 0.75% over
the three month LIBOR rate. The credit facility contains covenants that limit
the indebtedness the Company may incur and the amount of annual capital
expenditures. The covenants also establish a minimum interest coverage ratio, a
maximum leverage ratio, and a minimum consolidated net worth. At December 31,
1998, the Company was in compliance with all covenants. In addition, the Company
is required to pay an annual fee depending on the leverage ratio, payable in
quarterly installments, on the unused portion of the revolving loan. The
commitment fee was 22.5 basis points at December 31, 1998. There were no
borrowings at December 31, 1998 under the revolving loan facility. The carrying
amount of the Company's term loan facility approximates fair value.
 
     In conjunction with the credit facility and as part of the Company's policy
to manage interest rate risk, the Company entered into an interest rate swap
agreement ("swap") with The First National Bank of Chicago, a subsidiary of Bank
One Corporation, on
 
                                      F-18
<PAGE>   90
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
April 3, 1998. At December 31, 1998, the swap had a notional principal amount of
$360 million. Under the terms of the swap, the Company agrees to receive a
floating rate of interest on the amount of the term loan facility based on a
three month LIBOR rate in exchange for payment of a fixed rate of interest of
5.88% per annum. The notional principal amount of the swap amortizes in equal
amounts with the principal balance of the term loan facility. As a result, the
Company has, in effect, converted its variable rate term debt to fixed rate debt
at 5.88% per annum for the entire term of the term loan facility, plus the
Credit Rate Spread.
 
     The following represents the schedule of current maturities for the term
loan facility (amounts in thousands):
 
<TABLE>
<CAPTION>
YEAR ENDED DECEMBER 31,
- -----------------------
<S>                               <C>
1999............................  $ 54,000
2000............................    72,000
2001............................    90,000
2002............................    96,000
2003............................    48,000
                                  --------
                                  $360,000
                                  ========
</TABLE>
 
     Prior to April 1, 1998, the Company maintained a $25,000,000 unsecured line
of credit with the Mercantile Bank National Association which was terminated
upon the consummation of the Bankers' Trust credit facility. Additionally, the
Company allowed another line of credit in the amount of $25 million to lapse on
October 31, 1997. Terms of the agreements were as follows: interest was charged
on the principal amount outstanding at a rate equal to any of the following
options which the Company, at its option shall select: (i) the bank's "prime
rate", (ii) a floating rate equal to the Bank's cost of funds rate plus 50 basis
points, or (iii) a fixed rate for periods of 30, 60, 90 or 180 days equal to the
LIBOR rate plus 50 basis points. Fees under the agreements on any unused portion
were charged at 10 basis points per year. At December 31, 1997, the Company had
no outstanding borrowings under this agreement, nor did it borrow any amounts
under these agreements during 1997.
 
7.  CORPORATE RESTRUCTURING
 
     During 1998, the Company recorded a pre-tax restructuring charge of
$1,651,000 ($1,002,000 after taxes or $0.03 per basic earnings per share and
$0.03 per dilutive earnings per share) associated with the Company closing the
non-PBM service operations of its wholly-owned subsidiary, PhyNet, Inc., and
transferring certain functions of its Express Scripts Vision Corporation to
another vision care provider.
 
                                      F-19
<PAGE>   91
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
<TABLE>
<CAPTION>
                                                     UTILIZED         BALANCE AT
                                         1998     ---------------    DECEMBER 31,
                                        CHARGE    CASH    NONCASH        1998
                                        ------    ----    -------    ------------
                                                 (AMOUNTS IN THOUSANDS)
<S>                                     <C>       <C>     <C>        <C>
Write-down of long-lived assets.......  $1,235    $ --     $704          $531
Employee transition costs for 61
  employees...........................     416     184       --           232
                                        ------    ----     ----          ----
                                        $1,651    $184     $704          $763
                                        ======    ====     ====          ====
</TABLE>
 
   
     The restructuring charge includes tangible assets to be disposed of being
written down to their net realizable value, less cost of disposal. Management
expects recovery to approximate its cost of disposal. Considerable management
judgment is necessary to estimate fair value, accordingly, actual results could
vary from such estimates. The Company anticipates completing the remainder of
the restructuring actions by the end of the third quarter of 1999.
    
 
8.  INCOME TAXES
 
     The income tax provision consists of the following:
 
<TABLE>
<CAPTION>
                                                      YEAR ENDED DECEMBER 31,
                                                   -----------------------------
                                                    1996       1997       1998
                                                   -------    -------    -------
                                                          (IN THOUSANDS)
<S>                                                <C>        <C>        <C>
Current provision:
  Federal........................................  $13,945    $19,048    $20,171
  State..........................................    2,480      2,779      3,049
  Foreign........................................      190        284        278
                                                   -------    -------    -------
     Total current provision.....................   16,615     22,111     23,498
                                                   -------    -------    -------
Deferred provision:
  Federal........................................      267       (714)     8,694
  State..........................................       50       (120)     1,374
                                                   -------    -------    -------
     Total deferred provision....................      317       (834)    10,068
                                                   -------    -------    -------
Total current and deferred provision.............  $16,932    $21,277    $33,566
                                                   =======    =======    =======
</TABLE>
 
                                      F-20
<PAGE>   92
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     A reconciliation of the statutory federal income tax rate and the effective
tax rate follows (The effect of foreign taxes on the effective tax rate for
1996, 1997 and 1998 is immaterial):
 
<TABLE>
<CAPTION>
                                                           YEAR ENDED DECEMBER 31,
                                                          -------------------------
                                                          1996      1997      1998
                                                          -----     -----     -----
<S>                                                       <C>       <C>       <C>
Statutory federal income tax rate.......................  35.0%     35.0%     35.0%
State taxes net of federal benefit......................   4.3       3.8       3.8
Non-deductible amortization of goodwill and customer
  contracts.............................................                       4.9
Other, net..............................................    --       0.1       0.3
                                                          ----      ----      ----
Effective tax rate......................................  39.3%     38.9%     44.0%
                                                          ====      ====      ====
</TABLE>
 
     The deferred tax assets and deferred tax liabilities recorded in the
consolidated balance sheet are as follows:
 
<TABLE>
<CAPTION>
                                                                DECEMBER 31,
                                                              -----------------
                                                               1997      1998
                                                              ------    -------
                                                               (IN THOUSANDS)
<S>                                                           <C>       <C>
Deferred tax assets:
  Allowance for bad debts...................................  $1,578    $ 8,013
  Inventory costing capitalization and reserves.............     675        684
  Accrued expenses..........................................     512     34,170
  Depreciation and property differences.....................              6,808
  Non-compete agreements....................................                933
  Other.....................................................      79         17
                                                              ------    -------
     Gross deferred tax assets..............................   2,844     50,625
Deferred tax liabilities:
  Depreciation and property differences.....................  (1,166)
  Other.....................................................     (91)      (462)
                                                              ------    -------
     Gross deferred tax liabilities.........................  (1,257)      (462)
                                                              ------    -------
Net deferred tax assets.....................................  $1,587    $50,163
                                                              ======    =======
</TABLE>
 
     The Company believes it is probable that the net deferred tax assets,
reflected above, will be realized in future tax returns primarily from the
generation of future taxable income.
 
9.  COMMITMENTS AND CONTINGENCIES
 
     The Company has entered into noncancellable agreements to lease certain
office and distribution facilities with remaining terms from one to eleven
years. Rental expense under the office and distribution facilities leases in
1996, 1997 and 1998 was $2,099,000,
 
                                      F-21
<PAGE>   93
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
$2,272,000 and $3,876,000, respectively. The future minimum lease payments due
under noncancellable operating leases is as follows:
 
<TABLE>
<CAPTION>
YEAR ENDED DECEMBER 31,
- -----------------------
<S>                             <C>
1999..........................  $ 5,555,000
2000..........................    5,960,000
2001..........................    5,873,000
2002..........................    5,758,000
2003..........................    5,667,000
Thereafter....................   28,648,000
                                -----------
                                $57,462,000
                                ===========
</TABLE>
 
     For the year ended December 31, 1998, approximately 56.2% of the Company's
pharmaceutical purchases were through one wholesaler. The Company believes other
alternative sources are readily available and that no other concentration risks
exist at December 31, 1998.
 
     In the ordinary course of business (which includes the business conducted
by ValueRx prior to the Company's acquisition on April 1, 1998), various legal
proceedings, investigations or claims pending have arisen against the Company
and its subsidiaries (ValueRx continues to be a party to several proceedings
that arose prior to April 1, 1998). The effect of these actions on future
financial results is not subject to reasonable estimation because considerable
uncertainty exists about the outcomes. Nevertheless, in the opinion of
management, the ultimate liabilities resulting from any such lawsuits,
investigations or claims now pending will not materially affect the consolidated
financial position, results of operations, or cash flows of the Company.
 
10.  EMPLOYEE BENEFIT PLANS
 
     RETIREMENT SAVINGS PLAN.  The Company offers all of its full-time employees
a retirement savings plan under Section 401(k) of the Internal Revenue Code.
Employees may elect to enter a written salary deferral agreement under which a
maximum of 10% of their salary (effective January 1, 1999 maximum deferral is
12%), subject to aggregate limits required under the Internal Revenue Code, may
be contributed to the plan. The Company matches the first $2,000 of the
employee's contribution for the year. For the year ended December 1996, 1997 and
1998, the Company made contributions of approximately $639,000, $909,000 and,
$1,751,000 respectively.
 
   
     EMPLOYEE STOCK PURCHASE PLAN.  In December 1998, the Company's Board of
Directors approved an employee stock purchase plan, effective March 1, 1999,
that qualifies under Section 423 of the Internal Revenue Code and permits all
employees, excluding certain management level employees, to purchase shares of
the Company's Class A Common Stock. Participating employees may elect to
contribute up to 10% of their salary to purchase common stock at the end of each
six month participation period at a purchase price equal to 85% of the fair
market value of the common stock at the end of the participation period. Class A
Common Stock reserved for future employee purchases under the plan was 250,000
at December 31, 1998.
    
 
                                      F-22
<PAGE>   94
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
   
     DEFERRED COMPENSATION PLAN.  In December, 1998, the Compensation Committee
of the Board of Directors approved a non-qualified deferred compensation plan
(the "Executive Deferred Compensation Plan"), effective January 1, 1999, that
provides benefits payable to eligible key employees at retirement, termination
or death. Benefit payments are funded by a combination of contributions from
participants and the Company. Participants become fully vested in Company
contributions on the third anniversary of the end of the plan year for which the
contribution is credited to their account. For 1999, the annual Company
contribution will be equal to 6% of each participant's total annual
compensation, with 25% being invested in the Company's Class A Common Stock and
the remaining being allocated to a variety of investment options. As a result,
of the implementation, the Company accrued as compensation expense $797,000 in
1998 as a past service contribution which is equal to 8% of each participant's
total annual cash compensation for the period of the participant's past service
with the Company in a senior executive capacity.
    
 
11.  COMMON STOCK
 
     The holders of Class A Common Stock have one vote per share, and the
holders of Class B Common Stock have ten votes per share. NYLIFE is the sole
holder of Class B Common Stock. Class B Common Stock converts into Class A
Common Stock on a share-for-share basis upon transfer (other than to New York
Life or its affiliates) and is convertible at any time at the discretion of the
holder. At December 31, 1998, NYLIFE and the holders of Class A Common Stock
have control over approximately 89.0% and 11.0%, respectively, of the combined
voting power of all classes of Common Stock.
 
     In April 1996, NYLIFE converted 5,980,000 shares of Class B Common Stock to
Class A Common Stock and sold the Class A shares in a public offering. The
Company did not receive any proceeds from the sale of these shares. The Company
sold an additional 2,300,000 Class A shares in the same stock offering and
received net proceeds of $52,592,000 after deducting expenses incurred in
connection with the offering.
 
   
     In October 1998, the Company announced a two-for-one stock split of its
Class A and Class B common stock for stockholders of record on October 20, 1998,
effective October 30, 1998. The split was effected in the form of a dividend by
issuance of one additional share of Class A Common Stock for each share of Class
A Common Stock outstanding and one additional share of Class B Common Stock for
each share of Class B Common Stock outstanding. The earnings per share and the
weighted average number of shares outstanding for basic and diluted earnings per
share have been adjusted for the stock split except on the Consolidated Balance
Sheet and the Consolidated Statement of Changes in Stockholder's Equity.
    
 
     As of December 31, 1998, the Company had repurchased a total of 475,000
shares of its Class A Common Stock under the open-market stock repurchase
program announced by the Company on October 25, 1996, although no repurchases
occurred during 1998. The Company's Board of Directors approved the repurchase
of up to 1,700,000 shares, and placed no limit on the duration of the program.
Future purchases, if any, will be in such amounts and at such times as the
Company deems appropriate based upon prevailing market and business conditions,
subject to certain restrictions in the credit agreement described above.
 
                                      F-23
<PAGE>   95
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     As of December 31, 1998, 5,807,000 shares of the Company's Class A Common
Stock have been reserved for issuance to organizations with which the Company
has signed contractual agreements (see Note 3).
 
12.  STOCK-BASED COMPENSATION PLANS
 
     At December 31, 1998, the Company has three fixed stock-based compensation
plans, which are described below.
 
     In April 1992, the Company adopted a stock option plan which it amended in
1995, which provides for the grant of nonqualified stock options and incentive
stock options to officers and key employees of the Company selected by the
Compensation Committee of the Board of Directors. Initially, a maximum of
1,400,000 shares of Class A Common Stock could be issued under the plan. That
amount increases annually each January 1, from January 1, 1993 to and including
January 1, 1999 by 140,000, to a maximum of 2,380,000 shares. By unanimous
written consent dated June 6, 1994, the Board of Directors adopted the Express
Scripts, Inc. 1994 Stock Option Plan, also amended in 1995, 1997 and 1998. A
total of 1,920,000 shares of the Company's Class A Common Stock has been
reserved for issuance under this plan. Under either plan, the exercise price of
the options may not be less than the fair market value of the shares at the time
of grant. The Compensation Committee has the authority to establish vesting
terms, and typically provides that the options vest over a five-year period from
the date of grant. The options may be exercised, subject to a ten-year maximum,
over a period determined by the Committee.
 
     In April 1992, the Company also adopted a stock option plan which was
amended in 1995 and 1996 and provides for the grant of nonqualified stock
options to purchase 48,000 shares to each director who is not an employee of the
Company or its affiliates. A maximum of 384,000 shares of Class A Common Stock
may be issued under this plan at a price equal to fair market value at the date
of grant. The plan provides that the options vest over a three- or five-year
period from the date of grant.
 
     The Company applies APB 25 and related interpretations in accounting for
its plans. Accordingly, no compensation cost has been recognized for its stock
options plans. Had compensation cost for the Company's stock based compensation
plans been determined based on the fair value at the grant dates for awards
under those plans consistent with the method prescribed by FAS 123, the
Company's net income and earnings per share would have been reduced to the pro
forma amounts indicated below. Note that due to the adoption of the methodology
prescribed by FAS 123, the pro forma results shown below only reflect the impact
of options granted in 1996, 1997 and 1998. Because future options may be granted
and vesting typically occurs over a five year period, the pro forma impact shown
for 1996, 1997 and 1998 is not necessarily representative of the impact in
future years.
 
                                      F-24
<PAGE>   96
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
<TABLE>
<CAPTION>
                                                    1996       1997       1998
                                                   -------    -------    -------
                                                          (IN THOUSANDS,
                                                      EXCEPT PER SHARE DATA)
<S>                                                <C>        <C>        <C>
Net income
  As reported....................................  $26,148    $33,429    $42,674
  Pro forma......................................   25,235     32,034     38,585
Basic earnings per share
  As reported....................................  $  0.81    $  1.02    $  1.29
  Pro forma......................................     0.78       0.98       1.16
Diluted earnings per share
  As reported....................................  $  0.80    $  1.01    $  1.27
  Pro forma......................................     0.77       0.97       1.14
</TABLE>
 
     The fair value of options granted (which is amortized to expense over the
option vesting period in determining the pro forma impact), is estimated on the
date of grant using the Black-Scholes multiple option-pricing model with the
following weighted average assumptions:
 
<TABLE>
<CAPTION>
                                                 1996         1997         1998
                                               ---------    ---------    ---------
<S>                                            <C>          <C>          <C>
Expected life of option......................  1-6 years    2-7 years    2-7 years
Risk-free interest rate......................  5.0-6.5%     5.7-6.6%     4.1-5.9%
Expected volatility of stock.................   30-50%         40%          44%
Expected dividend yield......................    None         None         None
</TABLE>
 
     A summary of the status of the Company's three fixed stock option plans as
of December 31, 1996, 1997 and 1998, and changes during the years ending on
those dates is presented below.
 
                                      F-25
<PAGE>   97
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
   
<TABLE>
<CAPTION>
                                     1996                 1997                 1998
                              ------------------   ------------------   ------------------
                                       WEIGHTED-            WEIGHTED-            WEIGHTED-
                                        AVERAGE              AVERAGE              AVERAGE
                                       EXERCISE             EXERCISE             EXERCISE
                              SHARES     PRICE     SHARES     PRICE     SHARES     PRICE
                              ------   ---------   ------   ---------   ------   ---------
                                               (SHARE DATA IN THOUSANDS)
<S>                           <C>      <C>         <C>      <C>         <C>      <C>
Outstanding at beginning of
  year......................  1,446     $10.30     1,677     $12.56      1,702    $17.21
Granted.....................    642      19.85       602      22.78      1,866     40.65
Exercised...................   (131)      9.98      (529)      8.80       (133)    14.71
Forfeited/cancelled.........   (280)     18.80       (48)     17.56       (655)    38.82
                              -----                -----                ------
Outstanding at end of
  year......................  1,677      12.56     1,702      17.21      2,780     28.02
                              =====                =====                ======
Options exercisable at year
  end.......................    756                  641                   800
Weighted-average fair value
  of options granted during
  the year..................  $6.57                $9.91                $18.07
</TABLE>
    
 
     The following table summarizes information about fixed stock options
outstanding at December 31, 1998:
 
<TABLE>
<CAPTION>
                                  OPTIONS OUTSTANDING                    OPTIONS EXERCISABLE
                       ------------------------------------------   -----------------------------
RANGE OF                                WEIGHTED-       WEIGHTED-                    WEIGHTED-
EXERCISE PRICES          NUMBER          AVERAGE         AVERAGE       NUMBER         AVERAGE
(SHARE DATA IN         OUTSTANDING      REMAINING       EXERCISE    EXERCISABLE       EXERCISE
THOUSANDS)             AT 12/31/98   CONTRACTUAL LIFE     PRICE     AT 12/31/98        PRICE
- ---------------        -----------   ----------------   ---------   ------------   --------------
<S>                    <C>           <C>                <C>         <C>            <C>
$ 3.25 - 15.25.......       561            5.33          $10.09         426            $ 8.71
 15.50 - 23.50.......       618            7.15           18.64         278             18.47
 24.50 - 35.63.......     1,013            8.99           31.22          96             26.02
 37.44 - 42.39.......       218            9.44           39.89
         55.13.......       370            9.96           55.13          --
                          -----                                         ---
$ 3.25 - 55.13.......     2,780            8.01           28.02         800             14.17
                          =====                                         ===
</TABLE>
 
13.  SEGMENT INFORMATION
 
     The Company is organized on the basis of services offered and has
determined that it has two reportable segments: PBM services and non-PBM
services (defined in Note 1 "organization and operations"). The Company manages
the pharmacy benefit within an operating segment which encompasses a
fully-integrated PBM service. The remaining three operating service lines (IVTx,
Specialty Distribution and Vision) have been aggregated into a non-PBM reporting
segment.
 
                                      F-26
<PAGE>   98
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     The following table presents information about the reportable segments for
the years ended December 31
 
<TABLE>
<CAPTION>
                                               PBM        NON-PBM      TOTAL
                                            ----------    -------    ----------
                                                      (IN THOUSANDS)
<S>                                         <C>           <C>        <C>
1996
Net revenues..............................  $  743,077    $30,538    $  773,615
Depreciation and amortization expense.....       6,273       434          6,707
Interest income...........................       3,509                    3,509
Interest expense..........................          51         8             59
Income before income taxes................      39,938     3,142         43,080
Total assets..............................     286,433    13,992        300,425
Capital expenditures......................       8,306     1,174          9,480
1997
Net revenues..............................  $1,191,173    $39,461    $1,230,634
Depreciation and amortization expense.....       9,704       766         10,470
Interest income...........................       6,080         1          6,081
Interest expense..........................         209        16            225
Income before income taxes................      52,529     2,177         54,706
Total assets..............................     385,330    17,178        402,508
Capital expenditures......................      10,782     2,235         13,017
1998
Net revenues..............................  $2,765,111    $59,761    $2,824,872
Depreciation and amortization
  expense(1)..............................      25,540       983         26,433
Interest income...........................       7,235         1          7,236
Interest expense(1).......................      20,218        12         20,230
Income before income taxes................      70,107     6,133         76,240
Total assets..............................   1,068,715    26,746      1,095,461
Capital expenditures......................      23,432       421         23,853
</TABLE>
 
- -------------------------
 
(1) The amortization expense for deferred financing fees ($609 in 1998) is
    included in interest expense on the Consolidated Statement of Operations and
    in depreciation and amortization on the Consolidated Statement of Cash
    Flows.
 
                                      F-27
<PAGE>   99
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
14.  QUARTERLY FINANCIAL DATA (UNAUDITED)
 
     The following table summarizes the quarterly financial data for the years
ended December 31, 1997 and 1998:
 
<TABLE>
<CAPTION>
                                                                                       EARNINGS
                                                SELLING,                               PER SHARE
                         NET      COST OF      GENERAL &      OPERATING     NET     ---------------
                       REVENUES   REVENUES   ADMINISTRATIVE    INCOME     INCOME    BASIC   DILUTED
                       --------   --------   --------------   ---------   -------   -----   -------
                                          (IN THOUSANDS, EXCEPT PER SHARE DATA)
<S>                    <C>        <C>        <C>              <C>         <C>       <C>     <C>
1997
March 31, 1997.......  $261,990   $237,298      $13,298        $11,394    $ 7,641   $0.23    $0.23
June 30, 1997........   300,515    274,906       13,733         11,876      8,131    0.25     0.25
September 30, 1997...   319,937    291,590       15,758         12,589      8,613    0.26     0.26
December 31, 1997....   348,192    315,373       19,828         12,991      9,044    0.27     0.27
1998
March 31, 1998.......  $371,362   $338,492      $18,826        $14,044    $ 9,878   $0.30    $0.29
June 30, 1998........   807,406    743,557       39,266         22,932      9,568    0.29     0.28
September 30, 1998...   807,319    738,544       43,153         25,622     11,303    0.34     0.34
December 31, 1998....   838,784    764,403       47,745         26,636     11,924    0.36     0.35
</TABLE>
 
15.  SUBSEQUENT EVENT -- POTENTIAL ACQUISITION
 
   
     On February 9, 1999, the Company announced that it had executed a
definitive agreement to purchase Diversified Pharmaceutical Services, Inc
("DPS"), a wholly-owned subsidiary of SmithKline Beecham Corporation. Under the
terms of the agreement, the Company will pay cash in the amount of $700 million
for the stock of DPS. The Company expects to finance the purchase through a $1.1
billion bank credit facility consisting of an $800 million term facility and a
$300 million revolving credit facility. In addition, the Company has secured
bridge financing in the amount of $150 million to facilitate closing. The loan
proceeds will be used towards the $700 million purchase price and acquisition
related costs, and will also be used to refinance the Company's existing $440
million bank credit facility (see Note 6) and provide for working capital needs,
if any. The Company expects to issue $350 million in Class A Common Stock
through an offering. Net proceeds from the offering will be used to retire the
$150 million bridge facility and a portion of the $800 million term facility.
The acquisition will be accounted for under the purchase method of accounting
and is subject to customary closing conditions including required governmental
approvals and consummation and funding of the bank credit facility. The Company
anticipates the transaction will close in the second quarter of 1999.
    
 
   
     Should the transaction close and the Company refinance its existing $440
million bank credit facility, the remaining unamortized deferred financing fees
will be expensed as an extraordinary item. The Company anticipates maintaining
its existing interest rate swap in place to hedge the future variable interest
rate payments on $360 million of the new $1.1 billion bank credit facility.
    
 
     The following unaudited pro forma information presents a summary of
combined results of operations of the Company, the Acquired Entities and DPS as
if the acquisitions
 
                                      F-28
<PAGE>   100
                             EXPRESS SCRIPTS, INC.
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
   
and related financing, including the equity offering, had occurred at the
beginning of the period presented, along with certain pro forma adjustments to
give effect to amortization of goodwill, other intangible assets, interest
expense on acquisition debt and other adjustments. The pro forma financial
information is not necessarily indicative of the results of operations as they
would have been had the transaction been effected on the assumed dates. Included
in the pro forma information are integration costs incurred by the Company for
the Acquired Entities that are being reported within selling, general and
administrative expenses in the statement of operations.
    
 
<TABLE>
<CAPTION>
                                                   YEAR ENDED
                                                DECEMBER 31, 1998
                                              ---------------------
                                              (IN THOUSANDS, EXCEPT
                                                 PER SHARE DATA)
<S>                                           <C>
Net revenues................................       $3,449,649
Net income..................................           51,130
Basic earnings per share....................             1.36
Diluted earnings per share..................             1.34
</TABLE>
 
                                      F-29
<PAGE>   101
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
         (A WHOLLY OWNED SUBSIDIARY OF SMITHKLINE BEECHAM CORPORATION)
 
                              FINANCIAL STATEMENTS
 
                      AS OF DECEMBER 31, 1997 AND 1998 AND
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1997 AND 1998
 
                                      F-30
<PAGE>   102
 
                       REPORT OF INDEPENDENT ACCOUNTANTS
 
To the Stockholder of
Diversified Pharmaceutical Services, Inc.:
 
     In our opinion, the accompanying balance sheets and the related statements
of operations, stockholder's equity and cash flows, after the restatements
described in Notes 2 and 12, with which we concur, present fairly, in all
material respects, the financial position of Diversified Pharmaceutical
Services, Inc. and subsidiary (the "Company"), wholly owned by SmithKline
Beecham Corporation, at December 31, 1997 and 1998, and the results of their
operations and their cash flows for each of the three years in the period ended
December 31, 1998 in conformity with generally accepted accounting principles.
These financial statements are the responsibility of the Company's management;
our responsibility is to express an opinion on these financial statements based
on our audits. We conducted our audits of these statements in accordance with
generally accepted auditing standards which require that we plan and perform the
audit to obtain reasonable assurance about whether the financial statements are
free of material misstatement. An audit includes examining, on a test basis,
evidence supporting the amounts and disclosures in the financial statements,
assessing the accounting principles used and significant estimates made by
management, and evaluating the overall financial statement presentation. We
believe that our audits provide a reasonable basis for the opinion expressed
above.
 
PricewaterhouseCoopers LLP
Minneapolis, Minnesota
February 26, 1999, except
  Note 12 for which the date
  is March 1, 1999
 
                                      F-31
<PAGE>   103
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                                 BALANCE SHEETS
                        AS OF DECEMBER 31, 1997 AND 1998
 
<TABLE>
<CAPTION>
                                                      1997              1998
                                                 --------------    --------------
<S>                                              <C>               <C>
ASSETS
Cash...........................................  $      618,859    $    1,685,600
Receivables:
  SmithKline Beecham Corporation...............     343,589,242       371,827,141
  Accounts receivable, net.....................      81,452,718        82,746,292
                                                 --------------    --------------
     Total receivables.........................     425,041,960       454,573,433
Deferred tax asset.............................       1,400,000         1,880,237
Other current assets...........................       2,510,254         1,968,869
                                                 --------------    --------------
     Total current assets......................     429,571,073       460,108,139
Investment in joint venture....................       8,534,000         6,610,471
Furniture and equipment, net...................      13,505,083        14,910,412
Internal use software, net.....................              --        12,482,501
Goodwill and intangible assets, net............   1,998,439,000       832,497,469
Notes receivable...............................         511,597           511,597
Deferred tax asset.............................      42,029,677       430,374,187
                                                 --------------    --------------
     Total assets..............................  $2,492,590,430    $1,757,494,776
                                                 ==============    ==============
LIABILITIES AND STOCKHOLDER'S EQUITY
Liabilities:
  Rebates and pharmacy claims payable..........     206,053,314       191,726,763
  Accrued expenses.............................      52,876,383        51,779,710
  Deferred revenues............................       1,384,873         1,374,076
                                                 --------------    --------------
     Total current liabilities.................     260,314,570       244,880,549
Commitments and contingencies
Stockholder's equity:
  Common stock, $.01 par value; 1,000 shares
     authorized, 100 shares issued and
     outstanding...............................               1                 1
  Additional paid-in capital...................   2,108,416,415     2,110,981,415
  Retained earnings (Accumulated deficit)......     123,859,444      (598,367,189)
                                                 --------------    --------------
     Total stockholder's equity................   2,232,275,860     1,512,614,227
                                                 --------------    --------------
     Total liabilities and stockholder's
       equity..................................  $2,492,590,430    $1,757,494,776
                                                 ==============    ==============
</TABLE>
 
The accompanying notes are an integral part of the financial statements.
 
                                      F-32
<PAGE>   104
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                            STATEMENTS OF OPERATIONS
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1997 AND 1998
 
<TABLE>
<CAPTION>
                                           1996           1997            1998
                                       ------------   ------------   ---------------
<S>                                    <C>            <C>            <C>
Net revenues.........................  $692,046,016   $228,616,730   $   214,848,958
                                       ------------   ------------   ---------------
Operating expenses:
  Pharmacy claims, net...............   490,370,203     58,685,047           548,258
  Other selling, general and
     administrative..................   155,947,282    146,839,849       154,335,922
  Depreciation and amortization......    78,791,400     79,149,287        80,141,066
  Cost of pharmaceutical
     distribution....................    48,466,917             --                --
  Write down of assets...............            --             --     1,092,183,531
                                       ------------   ------------   ---------------
     Total operating expenses........   773,575,802    284,674,183     1,327,208,777
                                       ------------   ------------   ---------------
Operating loss.......................   (81,529,786)   (56,057,453)   (1,112,359,819)
Gain on transfer of subsidiary net
  assets to joint venture............    19,849,000             --                --
Equity in loss of joint venture......      (631,480)    (4,200,231)       (1,923,529)
Royalty income (Note 2)..............       695,054      4,010,792         3,231,968
Other income.........................       432,087             --                --
                                       ------------   ------------   ---------------
  Loss before income taxes...........   (61,185,125)   (56,246,892)   (1,111,051,380)
Benefit for income taxes.............    21,047,574     20,960,217       388,824,747
                                       ------------   ------------   ---------------
Net loss.............................  $(40,137,551)  $(35,286,675)  $  (722,226,633)
                                       ============   ============   ===============
</TABLE>
 
The accompanying notes are an integral part of the financial statements.
 
                                      F-33
<PAGE>   105
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                       STATEMENTS OF STOCKHOLDER'S EQUITY
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1997 AND 1998
 
<TABLE>
<CAPTION>
                                                                        RETAINED
                                    COMMON STOCK       ADDITIONAL       EARNINGS
                                   ---------------      PAID-IN       (ACCUMULATED
                                   SHARES   AMOUNT      CAPITAL         DEFICIT)          TOTAL
                                   ------   ------   --------------   -------------   --------------
<S>                                <C>      <C>      <C>              <C>             <C>
Balances, December 31, 1995......   100       $1     $2,105,981,415   $ 199,283,670   $2,305,265,086
Net loss.........................             --                 --     (40,137,551)     (40,137,551)
Allocation of expenses paid by SB
  Corp (Note 12).................             --          1,286,000              --        1,286,000
                                    ---       --     --------------   -------------   --------------
Balances, December 31, 1996......   100        1      2,107,267,415     159,146,119    2,266,413,535
Net loss.........................             --                 --     (35,286,675)     (35,286,675)
Allocation of expenses paid by SB
  Corp (Note 12).................             --          1,149,000              --        1,149,000
                                    ---       --     --------------   -------------   --------------
Balances, December 31, 1997......   100        1      2,108,416,415     123,859,444    2,232,275,860
Net loss.........................             --                 --    (722,226,633)    (722,226,633)
Allocation of expenses paid by SB
  Corp (Note 12).................             --          2,565,000              --        2,565,000
                                    ---       --     --------------   -------------   --------------
Balances, December 31, 1998......   100       $1     $2,110,981,415   $(598,367,189)  $1,512,614,227
                                    ===       ==     ==============   =============   ==============
</TABLE>
 
The accompanying notes are an integral part of the financial statements.
 
                                      F-34
<PAGE>   106
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                            STATEMENTS OF CASH FLOWS
                          INCREASE (DECREASE) IN CASH
              FOR THE YEARS ENDED DECEMBER 31, 1996, 1997 AND 1998
 
<TABLE>
<CAPTION>
                                                    1996            1997            1998
                                                -------------   ------------   --------------
<S>                                             <C>             <C>            <C>
Operating activities:
  Net loss....................................  $ (40,137,551)  $(35,286,675)  $ (722,226,633)
  Adjustments to reconcile net loss to net
     cash provided by operating activities:
     Deferred income taxes....................    (21,047,574)   (20,960,217)    (388,824,747)
     Allocation of expenses paid by SB Corp...      1,286,000      1,149,000        2,565,000
     Depreciation and amortization............     78,791,400     79,149,287       80,141,066
     Provision for bad debts..................      1,157,416        150,679        1,891,782
     Loss on disposal of furniture and
       equipment..............................        269,150             --        1,355,731
     Write down of assets.....................             --             --    1,092,183,531
     Net gain on transfer of subsidiary net
       assets to joint venture................    (19,849,000)            --               --
     Equity in loss of joint venture..........        631,480      4,200,231        1,923,529
     Changes in assets and liabilities, net of
       effects of assets transferred to joint
       venture:
     Accounts receivable......................    (17,410,844)   134,433,011       (3,185,356)
     Other current assets.....................     (3,675,967)     1,441,311          541,385
     Pharmacy claims and rebates payable......    128,821,042    (82,869,288)     (14,326,551)
     Accrued expenses.........................      2,858,448     13,575,278       (1,096,673)
     Deferred revenues........................    (23,085,416)    (2,504,104)         (10,797)
                                                -------------   ------------   --------------
     Net cash provided by operating
       activities.............................     88,608,584     92,478,513       50,931,267
                                                -------------   ------------   --------------
Investing activities:
  Increase in receivable from SmithKline
     Beecham Corporation......................   (103,708,181)   (88,017,729)     (28,237,899)
  Purchase of furniture and equipment, net of
     effects of assets transferred to joint
     venture..................................    (12,081,717)    (1,390,225)      (7,801,578)
  Proceeds received in connection with
     establishing joint venture...............     29,214,000             --               --
  Contribution to joint venture...............     (1,500,000)    (2,500,000)              --
  Issuance of notes receivable................             --       (511,597)              --
  Internal use software costs.................             --             --      (14,130,045)
  Proceeds received on disposal of furniture
     and equipment............................             --             --          304,996
                                                -------------   ------------   --------------
     Net cash used in investing activities....    (88,075,898)   (92,419,551)     (49,864,526)
                                                -------------   ------------   --------------
Net increase in cash..........................        532,686         58,962        1,066,741
Cash, as of beginning of year.................         27,211        559,897          618,859
                                                -------------   ------------   --------------
Cash, as of end of year.......................  $     559,897   $    618,859   $    1,685,600
                                                =============   ============   ==============
</TABLE>
 
The accompanying notes are an integral part of the financial statements.
 
                                      F-35
<PAGE>   107
 
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                         NOTES TO FINANCIAL STATEMENTS
 
1.  ORGANIZATION AND BACKGROUND:
 
     Diversified Pharmaceutical Services, Inc. (Diversified) is a wholly owned
subsidiary of SmithKline Beecham Corporation (SB Corp). SB Corp is a wholly
owned subsidiary of SmithKline Beecham plc (SB plc). Diversified's services
,which are all in a single operating segment, include the establishment of a
pharmacy provider network, installation and operation of a pharmacy claims
processing system, establishment and administration of a manufacturer rebate
program with respect to brand-name prescription drug products, and maintenance
of a prescription information database. In addition, Diversified provides drug
formulary development and maintenance along with maximum allowable costs (MAC)
lists for generic drugs. Diversified also assists its clients in utilization
management. From March 6, 1995 to October 28, 1996, Diversified's services also
included dispensing (through a wholly owned subsidiary, Diversified Prescription
Delivery, a mail service pharmacy subsidiary) medications and products to
patients for outpatient usage. On February 9, 1999, SB Corp entered into an
agreement to sell Diversified (see note 11).
 
2.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:
 
BASIS OF PRESENTATION:
 
Financial Statements:
 
     On May 27, 1994, SB Corp acquired the common stock of Diversified from
United Healthcare Corporation (UHC) for $2.3 billion in cash (the Acquisition).
Identifiable intangible assets, primarily existing customer relationships, of
approximately $0.4 billion recorded in connection with the Acquisition are being
amortized over their estimated useful lives ranging from 5 to 16 years. Goodwill
of approximately $1.8 billion recorded in connection with the Acquisition is
being amortized over 40 years.
 
     The financial statements as of December 31, 1997 and for the years ended
December 31, 1997 and 1996, have been restated to reflect the historical cost
basis of SB Corp and give effect to the impact of purchase accounting as a
result of the Acquisition. Previously issued financial statements do not give
effect to the Acquisition. The restatement resulted in an increase in total
equity of $2,147,376,886, $2,094,216,360 and $2,039,416,427 at December 31,
1995, 1996 and 1997, respectively, and a decrease in net income of $46,682,933
in both 1997 and 1996.
 
     In connection with the Acquisition, Diversified and SB Corp entered into a
six-year cooperation agreement with UHC, under which UHC will provide certain
data and provide support for outcomes research and other services. UHC will
receive a fixed percentage of Diversified's total annual formulary-managed drug
expenditures as a fee under this agreement. Such fees, included in other
selling, general and administrative expenses, were approximately $27.0 million,
$28.0 million and $33.8 million in 1996, 1997 and 1998, respectively. In
addition, UHC agreed to use Diversified as the pharmacy benefit manager for all
of UHC's health plans for the term of the aforementioned cooperation agreement.
 
Acquisition of DPD:
 
     On March 6, 1995, Diversified acquired all the common stock of Prescription
Delivery Services, a mail service pharmacy provider for approximately $15.0
million in cash. In connection with this acquisition, SB Corp made a capital
contribution of $15.0 million to
 
                                      F-36
<PAGE>   108
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
Diversified to fund the purchase of the net assets of Prescription Delivery
Services. The acquired entity was subsequently named Diversified Prescription
Delivery (DPD), and was reported as a wholly owned subsidiary of Diversified.
 
DPD Joint Venture:
 
     On October 28, 1996, Diversified entered into an agreement (the Agreement)
with another entity (the joint owner) to form and to jointly own and operate a
limited liability company to engage in the mail service pharmacy business. The
name of the new company is Diversified Prescription Delivery L.L.C. (the Joint
Venture). Concurrent with the execution of the Agreement, Diversified
transferred all the assets and liabilities of DPD plus $1.5 million of cash to
the Joint Venture. Simultaneously, the joint owner transferred certain
contracts, bids and liabilities plus $30.7 million of cash to the Joint Venture.
In accordance with the terms of the Limited Liability Company Agreement, the
Joint Venture then paid $29.2 million of cash to Diversified. Diversified and
the joint owner share management control and profits or losses equally. In
substance, Diversified sold half of its interest in the net assets of DPD to the
joint owner for $29.2 million and, accordingly, recorded a gain on the transfer
of subsidiary net assets to the Joint Venture of $19.8 million.
 
     The Diversified investment in this Joint Venture is being accounted for
using the equity method of accounting. Diversified's 50% share of the net losses
of the Joint Venture for the period from October 28, 1996 through December 31,
1996 and for the years ended December 31, 1997 and 1998, have been included in
equity in loss of joint venture on the statements of operations.
 
     On October 28, 1996, Diversified also entered into a Trademark License
Agreement and a Royalty Agreement with the Joint Venture to allow it to use
certain trademarks owned by Diversified. Pursuant to this Trademark License
Agreement, the Joint Venture has agreed to pay Diversified between 2 and 4
percent of certain revenues, as defined.
 
     Unaudited condensed financial information of the Joint Venture as of
December 31, 1997 and 1998 and for the years then ended is summarized below (in
thousands):
 
<TABLE>
<CAPTION>
                                                      1997       1998
                                                     -------    -------
<S>                                                  <C>        <C>
Current assets.....................................  $12,081    $15,587
Noncurrent assets..................................   16,043     11,270
Current liabilities................................   10,033      5,901
Members' equity....................................   17,068     13,221
DPD net loss.......................................    8,400      3,847
</TABLE>
 
     DPD's net loss for the period from October 28, 1996 through December 31,
1996 was approximately $1,263,000.
 
FURNITURE AND EQUIPMENT:
 
     Furniture, fixtures and computer equipment are recorded at cost. The cost
of additions and improvements are capitalized, while maintenance and repairs are
expensed as incurred.
 
                                      F-37
<PAGE>   109
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
Depreciation is provided for using the straight-line method over the following
estimated useful lives:
 
<TABLE>
<S>                                                 <C>
Furniture and fixtures............................  5 - 10 years
Computer equipment................................       3 years
</TABLE>
 
     Leasehold improvements are stated at cost. These amounts are amortized over
the estimated useful life of leasehold improvements or the remaining term of the
lease, whichever is shorter.
 
INTERNAL USE SOFTWARE:
 
     Software development costs are costs incurred in connection with the
development of computer software applications to support management services
provided by Diversified. Such costs, which include dedicated staff costs and
third party costs pursuant to the development of computer software applications,
are amortized over their estimated useful lives of four years, beginning when
the related application has been implemented.
 
     Effective January 1, 1998, Diversified has adopted the provisions of
Statement of Position 98-1, "Accounting for the Costs of Computer Software
Developed or Obtained for Internal Use" (SOP 98-1). SOP 98-1 requires the
capitalization of certain costs incurred in connection with developing or
obtaining internal use software and provides guidance for determining whether
computer software is for internal use. All software development costs incurred
in 1996 and 1997 totaling approximately $16.0 million and $13.9 million,
respectively, were expensed. During 1998, approximately $14.1 million of
internal use software development costs were capitalized pursuant to SOP 98-1.
 
REBATES PAYABLE:
 
     Rebates payable represent amounts due to customers who participate in
Diversified's drug manufacturer rebate programs. These amounts are distributed
to customers periodically according to contracts and allocation schedules
established by Diversified. The estimates of the resulting liability is
continually reviewed and updated, and any adjustments resulting therefrom are
reflected in current operations.
 
REVENUE AND EXPENSE RECOGNITION:
 
     Diversified provides pharmacy benefit management services as described in
Note 1 to numerous customers throughout the United States.
 
     Pharmacy Services -- Pharmacy service revenues are received from customers
for providing pharmacy benefits on a guaranteed total cost (capitated) basis.
These revenues are recognized either on a per claim basis or per member, per
month basis over the life of the contract period. Revenues from certain pharmacy
services billed one month prior to service delivery are deferred until the next
month. As of December 31, 1998, there were no capitated contracts outstanding.
 
     Management Services -- Management services revenues include administrative
fees for services provided to customers and drug manufacturers.
 
                                      F-38
<PAGE>   110
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
     Management services to customers include pharmacy claims processing and
other administrative services provided on a fee for service basis. Revenues
relating to these services are recognized according to the terms of the
applicable contracts, either on a per claim basis or per member, per month
basis. Amounts received from customers and paid out by Diversified for pharmacy
claims reimbursements, other than those under capitated arrangements, are
excluded from revenues and expenses.
 
     Management services provided to drug manufacturers include various services
relating to administration of the manufacturer rebate program. Revenues relating
to these services are recognized as earned based on detailed drug utilization
data. Rebates payable to customers in accordance with the applicable contracts
are excluded from revenues and expenses.
 
     Pharmaceutical Distribution -- Pharmaceutical distribution revenues
represent mail service pharmacy revenues earned prior to October 28, 1996 that
were recognized when medication and products were shipped.
 
     Pharmacy Claims Expense -- Pharmacy claims expense includes claims paid,
claims in process and pending, and estimated unreported claims and charges by
pharmacies for services rendered to enrolled members under capitation
arrangements during the period.
 
     Cost of Pharmaceutical Distribution -- Cost of pharmaceutical distribution
includes the costs of medication and products distributed through the mail
service pharmacy operations prior to October 28, 1996. Such costs were
recognized when medication and products were shipped.
 
RECEIVABLE FROM SB CORP:
 
     Diversified participates in SB Corp's consolidated cash pool whereby SB
Corp sweeps Diversified's cash accounts on a daily basis in accordance with SB
Corp cash management practices.
 
ACCOUNTS RECEIVABLE:
 
     Accounts receivable, including unbilled amounts, represent amounts due from
manufacturers for administrative fees and rebates payable under Diversified's
rebate program and customer fee for service receivables.
 
INCOME TAXES:
 
     Diversified's operating results are included in the consolidated federal
income tax return of SB Corp. However, for financial reporting purposes,
Diversified's provision (benefit) for income taxes are computed on a separate
entity basis. Income tax expense (benefit) represents the taxes that would have
been payable (receivable) for the year and the change in deferred tax assets and
liabilities during the year.
 
     Deferred income taxes are recorded to reflect the tax consequences in
future years of differences between tax basis of assets and liabilities and
their financial reporting amounts at year end based on enacted tax laws and
statutory tax rates applicable to the periods in which the differences are
expected to affect taxable income.
 
                                      F-39
<PAGE>   111
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
USE OF ESTIMATES:
 
     The preparation of the financial statements in conformity with generally
accepted accounting principles requires management to make estimates and
assumptions that affect the reported amounts of assets and liabilities and
disclosure of contingent assets and liabilities at the dates of the financial
statements and the reported amounts of revenues and expenses during the
reporting periods. Actual results could differ from those estimates. The most
significant areas which require the use of management estimates relate to
manufacturer agreements and related accounts receivable. Recognition of such
revenues requires the use of estimated pharmaceutical and fulfillment volumes
and mix data, until actual volume and mix data becomes available. Changes in
estimated 1995 pharmacy and management service revenues recorded in 1996
resulted in a $24.5 million reduction in 1996 net revenues. Other significant
areas which require the use of management estimates include the allowance for
uncollectible accounts receivable and the estimated useful life of identifiable
intangibles, internal use software and goodwill.
 
3.  SELECTED BALANCE SHEET INFORMATION:
 
     Accounts receivable, net consisted of the following:
 
<TABLE>
<CAPTION>
                                                 1997           1998
                                              -----------    -----------
<S>                                           <C>            <C>
Accounts receivable.........................  $82,879,783    $84,892,951
Allowance for doubtful accounts.............   (1,427,065)    (2,146,659)
                                              -----------    -----------
  Accounts receivable, net..................  $81,452,718    $82,746,292
                                              ===========    ===========
</TABLE>
 
     Furniture and equipment consisted of the following:
 
<TABLE>
<CAPTION>
                                                 1997           1998
                                             ------------    -----------
<S>                                          <C>             <C>
Furniture and fixtures.....................  $ 10,893,684    $13,189,431
Computer equipment and purchased
  software.................................    10,059,836      6,695,083
Leasehold improvements.....................     5,213,657      2,914,698
Construction in progress...................            --        638,026
                                             ------------    -----------
                                               26,167,177     23,437,238
Less accumulated depreciation and
  amortization.............................   (12,662,094)    (8,526,826)
                                             ------------    -----------
  Furniture and equipment, net.............  $ 13,505,083    $14,910,412
                                             ============    ===========
</TABLE>
 
     Internal use software, net consisted of the following:
 
<TABLE>
<CAPTION>
                                                 1997           1998
                                              -----------    -----------
<S>                                           <C>            <C>
Internal use software.......................  $        --    $14,130,045
Less accumulated amortization...............           --     (1,647,544)
                                              -----------    -----------
  Internal use software, net................  $        --    $12,482,501
                                              ===========    ===========
</TABLE>
 
                                      F-40
<PAGE>   112
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
     Goodwill and intangibles, net consisted of the following:
 
<TABLE>
<CAPTION>
                                              1997              1998
                                         --------------    --------------
<S>                                      <C>               <C>
Customer List..........................  $  400,000,000    $  400,000,000
Acquired internally developed
  software.............................      12,500,000        12,500,000
Databank software......................       4,000,000         4,000,000
Goodwill...............................   1,850,230,000       758,046,469
                                         --------------    --------------
                                          2,266,730,000     1,174,546,469
Accumulated amortization...............    (268,291,000)     (342,049,000)
                                         --------------    --------------
Net balance............................  $1,998,439,000    $  832,497,469
                                         ==============    ==============
</TABLE>
 
     Amortization related to these intangibles and goodwill, excluding the
$1,092,183,531 write-down of goodwill discussed in Note 11, was $73,758,000 for
each of the three years in the period ended December 31, 1998.
 
4.  RELATED PARTY TRANSACTIONS:
 
     Diversified provided SB Corp with pharmacy benefit management services in
connection with its self-funded health plan in 1996, 1997 and 1998. Related
revenues for these services were $305,855, $234,923 and $269,017 in 1996, 1997
and 1998, respectively. SB Corp participates in Diversified's drug manufacturers
rebate program on terms similar to other participating manufacturers. Amounts
paid or payable by SB Corp under the program totaled approximately $10,400,000,
$7,900,000 and $7,200,000 in 1996, 1997 and 1998, respectively. In addition, SB
participates in utilization management programs on terms similar to other
participating manufacturers offered to Diversified's customers. Total revenue
from SB Corp related to the utilization management programs was $77,250 and
$810,000 in 1997 and 1998 respectively. No such revenues were generated by
Diversified in 1996. SB also purchases certain drug information products from
Diversified. These products provide manufacturers timely information about drug
utilization. Revenue from SB Corp for these information products was $5,000 and
$1,203,369 in 1997 and 1998, respectively. No such revenues were generated by
Diversified in 1996. Included in accounts receivable is $4,267,454 and
$1,910,694 from SB Corp as of December 31, 1997 and 1998, respectively.
 
     Corporate services, overhead and other expenses are charged to Diversified
by SB Corp and to SB Corp by Diversified wherever possible on a direct basis,
such as resource usage or dedicated support percentage. The net expense from
these charges was approximately $5,100,000, $600,000 and $1,300,000 in 1996,
1997 and 1998, respectively, and are included in selling, general and
administrative expenses in the accompanying statements of operations.
 
     Diversified incurred pharmacy claims expense of $5,198,749 in 1996 related
to Diversified Prescription Delivery L.L.C. for services performed for one of
Diversified's customers. Diversified paid on behalf of Diversified Prescription
Delivery L.L.C. disbursements of $1,326,249, $1,720,911 and $1,231,005 in 1996,
1997 and 1998, respectively, consisting of salaries, benefits, and other
services. Such amounts are billed to
 
                                      F-41
<PAGE>   113
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
Diversified Prescription Delivery L.L.C. in the year incurred. In addition, in
1996, 1997 and 1998, Diversified earned royalties from Diversified Prescription
Delivery L.L.C. (Note 2) totaling $695,054, $4,010,792 and $3,231,968,
respectively. Included in accounts receivable are amounts receivable from
Diversified Prescription Delivery L.L.C. of $2,903,750 and $5,468,694 as of
December 31, 1997 and 1998, respectively.
 
     At December 31, 1997 and 1998, Diversified has a total of $511,597
noninterest bearing notes receivable from Diversified Prescription Delivery
L.L.C. Although these notes are payable on demand, Diversified does not expect
to require repayment of them in 1999 and has therefore classified them as
long-term assets.
 
5.  SIGNIFICANT CUSTOMERS:
 
     Diversified recognized revenues for providing UHC with pharmacy benefit
management services of $389,502,444, $75,574,757 and $116,045,072 in 1996, 1997
and 1998, respectively. These revenues totaled approximately 56.3 percent, 33.1
percent and 54.0 percent of total revenues for the years ended December 31,
1996, 1997 and 1998, respectively.
 
     In 1996, the agreement with UHC was structured on a capitated risk-sharing
basis. Adjustments to the amount payable to Diversified for services provided
were to be made based upon UHC's actual pharmacy claims experience. The
structure of the pharmacy benefit management agreement between Diversified and
UHC changed as of January 1, 1997 and contains a cost-based fee arrangement.
This agreement provides for UHC to pay all pharmacy claims and pharmacy benefit
management costs as incurred.
 
     Total amounts receivable, from UHC including the provisions disclosed
above, were $10,988,971 and $4,970,219 as of December 31, 1997 and 1998,
respectively.
 
     Corporate charges for services from UHC totaled $4,996,148, $1,366,498 and
$998,544 in 1996, 1997 and 1998, respectively. These charges are for services
provided by UHC to Diversified.
 
     Receivables from two customers represented 13.5 percent and 13.2 percent of
accounts receivable as of December 31, 1997. Receivables from two customers
represented 19.1 percent and 17.3 percent of the accounts receivable as of
December 31, 1998.
 
                                      F-42
<PAGE>   114
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
6.  COMMITMENTS AND CONTINGENCIES:
 
     Diversified is obligated under various noncancelable operating leases for
office facilities and equipment. These operating leases expire at various dates
through 2008. Rent expense was $6,121,964, $6,843,070 and $7,671,347 for 1996,
1997 and 1998, respectively. Future minimum rental payments required under
noncancelable operating leases with initial or remaining lease terms in excess
of one year as of December 31, 1998 are as follows:
 
<TABLE>
<S>                                                         <C>
1999......................................................  $ 6,311,202
2000......................................................    6,287,416
2001......................................................    6,070,773
2002......................................................    5,118,824
2003......................................................    5,148,122
Thereafter................................................   23,682,366
                                                            -----------
                                                            $52,618,703
                                                            ===========
</TABLE>
 
     Diversified is party to certain disputes that arise in the normal course of
business. While the outcome of these matters cannot be predicted with certainty,
management presently believes that resulting adjustments, if any, would not have
a material effect on the financial position, results of operations or liquidity
of Diversified.
 
7.  RETIREMENT PLANS:
 
MULTIEMPLOYER PENSION PLAN:
 
     Diversified employees are eligible to participate in the SmithKline Beecham
Pension Plan, a multiemployer pension plan (the Pension Plan). Contributions to
the Pension Plan are determined in accordance with actuarial determinations made
by SB Corp. Diversified contributed $545,100, $900,000 and $1,152,000 to the
Pension Plan in 1996, 1997 and 1998, respectively.
 
OTHER EMPLOYEE BENEFIT PLANS:
 
     Diversified participates in the SB Corp 401(k) Savings Plan (the Plan). All
employees of Diversified who have worked at least 900 hours in a year and have
met certain employment period requirements, as defined by the Plan, are eligible
to participate. Participants may contribute up to 15% of their eligible
compensation. Diversified matches a percentage of employees' contributions to
the Plan. Diversified contributed $2,247,695, $973,197 and $1,285,817 to the
Plan in 1996, 1997 and 1998, respectively.
 
     Effective January 1, 1999, SB Corp redesigned the pension plans and 401(k)
savings plans which resulted in the addition of an SB Corp. stock investment
option and modification of certain eligibility and vesting terms.
 
8.  STOCK OPTION PLAN:
 
     SB plc offers a stock option incentive program for certain employees. The
options are granted annually at exercise prices equal to the market value of the
stock as of the date of grant. Stock options vest after three years from the
date of grant and must be exercised
 
                                      F-43
<PAGE>   115
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
within 10 years from the date of grant. Diversified and SB plc follows the
method of accounting for employee stock compensation plans prescribed by APB No.
25, which is permitted by Statement of Financial Accounting Standards No. 123,
"Accounting for Stock-Based Compensation" (SFAS No. 123). In accordance with APB
No 25, the Company has not recognized compensation expense for stock options
because the exercise price of the options equal the market price of the
underlying stock on the date of the grant, which is the measurement date.
Certain management personnel of Diversified received SB plc stock options. If
Diversified had followed the fair value method for stock option plans in
accordance with SFAS No. 123 in 1996, 1997 and 1998, the net loss would have
increased by approximately $300,000, $1,000,000 and $2,300,000, respectively,
for each of the years then ended.
 
     The fair value of the options granted are estimated using the Black-Scholes
option pricing model with the following assumptions: dividend yield of 1.6.%
(1996 -- 2.6%), volatility of 32% (1996 -- 22%), risk free investment rate of
6.5% (1996 -- 7.5%), assumed forfeiture rate of 1% and an expected life of seven
years.
 
9.  INCOME TAXES:
 
     Income tax benefit consisted of the following:
 
<TABLE>
<CAPTION>
                                1996            1997            1998
                            ------------    ------------    -------------
<S>                         <C>             <C>             <C>
Current tax (benefit).....  $         --    $         --    $          --
Deferred tax expense
  (benefit)...............   (21,047,574)    (20,960,217)    (388,824,747)
                            ------------    ------------    -------------
  Benefit for income
     taxes................  $(21,047,574)   $(20,960,217)   $(388,824,747)
                            ============    ============    =============
</TABLE>
 
     The taxable income of Diversified is included in the consolidated federal
income tax return of SB Corp. Diversified's income taxes are based on the
approximate amount that would have been computed on a separate company basis
utilizing the statutory federal and state tax rates on Diversified's earnings.
 
     In 1996, 1997 and 1998, the difference between the federal statutory income
tax rate and the effective rate was primarily due to state income taxes.
 
     Due to certain elections made by SB Corp at the date of acquisition, to
achieve a step-up in the tax basis of Diversified's assets, Diversified would
not (on a separate tax return basis) be required to pay federal income taxes for
the foreseeable future due to the deductibility of the amortization of goodwill
and intangibles relating to SB Corp's acquisition of Diversified. Such
amortization would offset Diversified's separate company taxable income. The
deferred tax asset and related tax benefit is also reflected in Diversified's
financial statements as if Diversified filed on a separate tax return basis.
 
     Diversified's net deferred tax assets and liabilities as of December 31,
1997 and 1998 relate primarily to goodwill and intangibles.
 
                                      F-44
<PAGE>   116
            DIVERSIFIED PHARMACEUTICAL SERVICES, INC. AND SUBSIDIARY
 
                  NOTES TO FINANCIAL STATEMENTS -- (CONTINUED)
 
10.  DISCLOSURES ABOUT FAIR VALUE OF FINANCIAL INSTRUMENTS:
 
     The carrying amounts reported in the balance sheet for cash, receivables
and notes receivable approximate fair value due to the short maturity of these
instruments.
 
     There are no quoted market prices for Diversified's investment in joint
venture. Therefore, Diversified believes it is not practical to estimate a fair
market value different from the investment in joint venture carrying value.
 
11.  SUBSEQUENT EVENT:
 
     On February 9, 1999, SB Corp entered into an agreement to sell all of the
outstanding stock of Diversified in exchange for $700,000,000 of cash and the
unconditional termination of the SB Corp. receivables owed to Diversified.
Completion of the transaction, subject to regulatory review, is expected during
the second quarter of 1999. The Company and SB Corp have also agreed that, prior
to the closing of the sale, the assets and liabilities related to Diversified's
investment in Diversified Prescription Delivery L.L.C. will be transferred to SB
Corp.
 
     As a result of the pending sale, management evaluated the recoverability of
the Company's long-lived assets, including goodwill and intangibles pursuant to
Statement of Financial Accounting Standards (SFAS) No. 121. In accordance with
SFAS No. 121, the Company recorded a provision of approximately $1.1 billion to
reduce the carrying value of certain long-lived assets. The tax benefit arising
from this charge has been recorded as a deferred tax asset in 1998. Also, as a
result of the above pending sale, the realizability of certain tax assets and
liabilities may be impacted.
 
12.  CORPORATE COST ALLOCATION:
 
     The financial statements of Diversified for the years ended December 31,
1996 and 1997, as previously prepared included direct costs incurred or
allocated to Diversified by SB Corp. Additional corporate overhead costs have
been included in these financial statements based on the relative percentage of
operating income of Diversified to the consolidated operating income of SB Corp
(excluding the effects of amortization of goodwill and intangible assets related
to SB Corp's acquisition of Diversified) which management believes is a
reasonable basis for such cost allocation. The following additional costs have
been included in Other selling, general and administrative on the statement of
operations.
 
<TABLE>
<CAPTION>
                                           1996           1997            1998
                                       ------------   ------------   ---------------
<S>                                    <C>            <C>            <C>
Loss before income taxes, as
  previously reported................  $(59,899,125)  $(55,097,892)  $(1,108,486,380)
Adjustments for expenses not
  previously allocated...............    (1,286,000)    (1,149,000)       (2,565,000)
                                       ------------   ------------   ---------------
Loss before income taxes, after
  allocated costs....................  $(61,185,125)  $(56,246,892)  $(1,111,051,380)
                                       ============   ============   ===============
</TABLE>
 
                                      F-45
<PAGE>   117
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
                    MANAGED PRESCRIPTION NETWORK, INC. D/B/A
                          COLUMBIA PHARMACY SOLUTIONS
 
               UNAUDITED COMBINED CONDENSED FINANCIAL STATEMENTS
 
                            AS OF MARCH 31, 1998 AND
               FOR THE THREE MONTHS ENDED MARCH 31, 1998 AND 1997
 
                                      F-46
<PAGE>   118
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
      MANAGED PRESCRIPTION NETWORK, INC. D/B/A COLUMBIA PHARMACY SOLUTIONS
 
                   UNAUDITED COMBINED CONDENSED BALANCE SHEET
 
<TABLE>
<CAPTION>
                                                                MARCH 31,
                                                                   1998
                                                                ---------
                                                              (IN THOUSANDS)
<S>                                                           <C>
ASSETS:
Current assets:
  Cash and Cash equivalents.................................     $ 26,863
  Receivables, less allowance for doubtful accounts of
     $25,310................................................      185,506
  Inventories...............................................       10,881
  Prepaid expenses and other current assets.................        3,320
  Deferred income taxes.....................................       41,737
                                                                 --------
     Total current assets...................................      268,307
Property and equipment, net.................................      100,769
Goodwill and other intangibles, net.........................      250,707
Other assets................................................        2,794
                                                                 --------
     Total assets...........................................     $622,577
                                                                 ========
 
LIABILITIES AND STOCKHOLDER'S EQUITY
Current liabilities:
  Payable to providers......................................     $162,853
  Accounts payable and accrued expenses.....................       57,501
                                                                 --------
     Total current liabilities..............................      220,354
Other liabilities...........................................        1,367
Stockholder's equity........................................      400,856
                                                                 --------
     Total liabilities and stockholder's equity.............     $622,577
                                                                 ========
</TABLE>
 
   
See notes to the unaudited combined condensed statements.
    
 
                                      F-47
<PAGE>   119
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
      MANAGED PRESCRIPTION NETWORK, INC. D/B/A COLUMBIA PHARMACY SOLUTIONS
 
              UNAUDITED COMBINED CONDENSED STATEMENT OF OPERATIONS
 
<TABLE>
<CAPTION>
                                                               THREE MONTHS ENDED
                                                             ----------------------
                                                               1998          1997
                                                               ----          ----
                                                                 (IN THOUSANDS)
<S>                                                          <C>           <C>
Net revenues...............................................  $409,928      $407,297
                                                             --------      --------
Cost and expenses:
  Cost of revenues.........................................   375,295       366,913
  Selling, general and administrative......................    27,628        18,552
                                                             --------      --------
                                                              402,923       385,465
                                                             --------      --------
Operating income...........................................     7,005        21,832
                                                             --------      --------
Other income (expense):
  Interest income..........................................        56           103
  Interest expense.........................................        --           (24)
                                                             --------      --------
                                                                   56            79
                                                             --------      --------
Income before income taxes.................................     7,061        21,911
Provision for income taxes.................................     3,665        10,832
                                                             --------      --------
Net income.................................................  $  3,396      $ 11,079
                                                             ========      ========
</TABLE>
 
   
See notes to the unaudited combined condensed statements.
    
 
                                      F-48
<PAGE>   120
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
      MANAGED PRESCRIPTION NETWORK, INC. D/B/A COLUMBIA PHARMACY SOLUTIONS
 
              UNAUDITED COMBINED CONDENSED STATEMENT OF CASH FLOW
 
<TABLE>
<CAPTION>
                                                              THREE MONTHS ENDED
                                                                   MARCH 31,
                                                              -------------------
                                                                1998       1997
                                                              --------   --------
                                                                (IN THOUSANDS)
<S>                                                           <C>        <C>
CASH FLOWS FROM OPERATING ACTIVITIES:
  Net income................................................  $  3,396   $ 11,079
  Adjustments to reconcile net income to net cash provided
     by operating activities:
     Depreciation and amortization..........................     8,811      4,537
     Provision for doubtful accounts........................       478      1,679
     Gain on disposal of assets.............................      (106)    (1,230)
     Deferred income taxes..................................        --      1,877
     Net changes in operating assets and liabilities........   (11,355)   (17,809)
                                                              --------   --------
Net cash provided by operating activities...................     1,224        133
                                                              --------   --------
CASH FLOWS FROM INVESTING ACTIVITIES:
  Purchases of property and equipment.......................    (5,216)   (14,236)
  Sale of investment........................................     6,000         --
                                                              --------   --------
Net cash provided by (used in) investing activities.........       784    (14,236)
                                                              --------   --------
CASH FLOWS USED IN FINANCING ACTIVITIES:
     Net (payments) receipts to/from parent.................    (7,220)    46,791
                                                              --------   --------
Net (decrease) increase in cash and cash equivalent.........    (5,212)    32,688
Cash and cash equivalent at beginning of period.............    32,075      9,370
                                                              --------   --------
Cash and cash equivalent at end of period...................  $ 26,863   $ 42,058
                                                              ========   ========
</TABLE>
 
   
See notes to the unaudited combined condensed statements.
    
 
                                      F-49
<PAGE>   121
 
                  VALUE HEALTH PHARMACY BENEFIT MANAGEMENT AND
      MANAGED PRESCRIPTION NETWORK, INC. D/B/A COLUMBIA PHARMACY SOLUTIONS
 
           NOTES TO UNAUDITED COMBINED CONDENSED FINANCIAL STATEMENTS
 
NOTE 1 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
 
     Financial statement note disclosures, normally included in financial
statements prepared in conformity with generally accepted accounting principles,
have been omitted in these combined condensed financial statements pursuant to
the Form 10-Q rules and Regulations of the Securities and Exchange Commission.
However, in the opinion of the Company, the disclosure contained herein are
adequate to make the information presented not misleading when read in
conjunction with the notes to combined financial statements of Value Health
Pharmacy Benefit Management ("Value Health, Inc.") for the Year Ended December
31, 1997 and the notes to financial statements of Managed Prescription Network,
Inc. d/b/a Columbia Pharmacy Solutions ("MPN") for the Year Ended December 31,
1997 included in the Company's Current Report on Form 8-K/A, as filed with the
Securities and Exchange Commission on June 12, 1998.
 
     In the opinion of the Company, the accompanying unaudited combined
condensed financial statements, including, Value Health, Inc. and MPN, reflect
all adjustments (consisting of only normal recurring adjustments) necessary to
present fairly the Combined Condensed Balance Sheet at March 31, 1998, the
Combined Condensed Statement of Operations for the three months ended March 31,
1998, and 1997, and the Condensed Combined Statement of Cash Flows for the three
months ended March 31, 1998, and 1997.
 
NOTE 2 - STOCKHOLDER'S EQUITY
 
The combined changes in stockholder's equity is as follows:
 
<TABLE>
<S>                                                         <C>
Balance at December 31, 1997..............................  $406,746
     Net income...........................................     3,396
     Net distributions to parent..........................    (9,286)
                                                            --------
Balance at March 31, 1998.................................  $400,856
                                                            ========
</TABLE>
 
NOTE 3 - SUBSEQUENT EVENTS
 
     On April 1, 1998, Express Scripts, Inc. announced that it had consummated
the acquisition of the outstanding common stock of VHI and MPN, the sole assets
of which are various subsidiaries each now or formerly conducting business as a
pharmacy benefit management company, from Columbia/HCA Healthcare Corporation
for approximately $460 million in cash.
 
                                      F-50
<PAGE>   122
 
                             [EXPRESS SCRIPTS LOGO]
<PAGE>   123
 
                                    PART II
 
                     INFORMATION NOT REQUIRED IN PROSPECTUS
 
ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION
 
     The expenses in connection with the issuance and distribution of the
securities being registered, other than underwriting discounts and commissions
(which are described in the prospectus), are estimated as follows:
 
<TABLE>
<S>                                                 <C>
Securities and Exchange Commission registration
  fee.............................................  $112,761.39
Legal fees and expenses...........................       *
Accounting fees and expenses......................       *
Printing and engraving expenses...................       *
Blue Sky filing fees and expenses.................       *
NASD filing fee...................................  $30,500.00
The Nasdaq National Market listing fee............       *
Miscellaneous expenses............................       *
     Total........................................  $
                                                    ===========
</TABLE>
 
- -------------------------
 
* To be included by amendment.
 
ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS
 
   
     Section 102(b)(7) of the General Corporation Law of the State of Delaware
(the "Delaware Law") enables a corporation in its original certificate of
incorporation or an amendment to eliminate or limit the personal liability of a
director to a corporation or its stockholders for violations of the director's
fiduciary duty, except (1) for any breach of a director's duty of loyalty to the
corporation or its stockholders, (2) for acts or omissions not in good faith or
which involve intentional misconduct or a knowing violation of law, (3) pursuant
to Section 174 of the Delaware Law (providing for liability of directors for
unlawful payment of dividends or unlawful stock purchases or redemptions) or (4)
for any transaction from which a director derived an improper personal benefit.
Our Amended and Restated Certificate of Incorporation provides for the
elimination of the liability of our directors to the extent permitted by Section
102(b)(7) of the Delaware Law.
    
 
     Section 145 of the Delaware Law provides, in summary, that directors and
officers of Delaware corporations are entitled, under certain circumstances, to
be indemnified against all expenses and liabilities (including attorney's fees)
incurred by them as a result of suits brought against them in their capacity as
a director or officer, if they acted in good faith and in a manner they
reasonably believed to be in or not opposed to our best interests, and, with
respect to any criminal action or proceeding, if they had no reasonable cause to
believe their conduct was unlawful; provided, that no indemnification may be
made against expenses in respect of any claim, issue or matter as to which they
shall have been adjudged to be liable to us, unless and only to the extent that
the court in which such action or suit was brought shall determine upon
application that, despite the adjudication of liability but in view of all the
circumstances of the case, they are fairly and reasonably entitled to indemnity
for such expenses which the court shall deem proper. Any such indemnification
may be made by us only as authorized in each specific case upon a determination
by our stockholders or disinterested directors that indemnification is proper
 
                                      II-1
<PAGE>   124
 
because the indemnitee has met the applicable standard of conduct. Article Seven
of our certificate of incorporation entitles our officers and directors to
indemnification to the fullest extent permitted by Section 145 of the Delaware
Law, as the same may be supplemented from time to time.
 
     Article Eight of our certificate of incorporation provides that no director
shall have any personal liability to us or our stockholders for any monetary
damages for breach of fiduciary duty as a director, provided that such provision
does not limit or eliminate the liability of any director (1) for breach of such
director's duty of loyalty to us or our stockholders, (2) for acts or omissions
not in good faith or which involve international misconduct or knowing violation
of the law, (3) under Section 174 of the Delaware Law (involving certain
unlawful dividends or stock repurchases) or (4) for any transaction from which
such director derived an improper personal benefit.
 
ITEM 16.  EXHIBITS
 
   
<TABLE>
<S>   <C>  <C>
 1.1   --  Form of Underwriting Agreement+
 4.0   --  Certificate of Class A Common Stock*
 5.1   --  Opinion of Simpson Thacher & Bartlett+
23.1   --  Consent of PricewaterhouseCoopers LLP
23.2   --  Consent of Ernst & Young LLP, Minneapolis, Minnesota
23.3   --  Consent of Ernst & Young LLP, Pittsburgh, Pennsylvania
           Consent of Simpson Thacher & Bartlett (included in Exhibit
23.4   --  5.1)+
24.1   --  Powers of attorney++
</TABLE>
    
 
- -------------------------
 
 * Incorporated by reference in our Registration Statement on Form 8-A dated May
   12, 1992.
 
 + To be filed by amendment.
 
   
++ Filed previously.
    
 
ITEM 17.  UNDERTAKINGS
 
   
     We undertake that, for purposes of determining any liability under the
Securities Act, each filing of our annual report pursuant to Section 13(a) or
Section 15(d) of the Exchange Act (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the Exchange
Act) that is incorporated by reference in this registration statement will be
deemed to be a new registration statement relating to the securities offered in
this registration statement, and the offering of such securities at that time
will be deemed to be the initial bona fide offering.
    
 
     Insofar as indemnification for liabilities arising under the Securities Act
may be permitted to our directors, officers and controlling persons pursuant to
the foregoing provisions, or otherwise, we have been advised that in the opinion
of the SEC such indemnification is against public policy as expressed in the
Securities Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by us of
expenses incurred or paid by our director, officer, or controlling person in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer, or controlling person in connection with the securities being
registered, we will, unless in the opinion of our counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction
the question whether such
 
                                      II-2
<PAGE>   125
 
indemnification by it is against public policy as expressed in the Securities
Act and will be governed by the final adjudication of such issue.
 
   
     We undertake that:
    
 
          (1) For purposes of determining any liability under the Securities
     Act, the information omitted from the form of prospectus filed as part of
     this registration statement in reliance upon Rule 430A and contained in a
     form of prospectus filed by us pursuant to Rule 424(b)(1) or (4) or 497(h)
     under the Securities Act shall be deemed to be part of this registration
     statement as of the time it was declared effective.
 
   
          (2) For the purpose of determining any liability under the Securities
     Act, each post-effective amendment that contains a form of prospectus shall
     be deemed to be a new registration statement relating to the securities
     offered in that registration statement, and the offering of such securities
     at that time shall be deemed to be the initial bona fide offering.
    
 
                                      II-3
<PAGE>   126
 
                                   SIGNATURES
 
   
     Pursuant to the requirements of the Securities Act, we certify that we have
reasonable grounds to believe that we meet all of the requirements for filing on
Form S-3 and have duly caused this registration statement to be signed on our
behalf by the undersigned, thereunto duly authorized, in the City of Maryland
Heights, State of Missouri on May 6, 1999.
    
 
                                          EXPRESS SCRIPTS, INC.
 
                                          BY:                  *
                                            ------------------------------------
                                          Barrett A. Toan, President and
                                            Chief Executive Officer
 
   
     Pursuant to the requirements of the Securities Act, this registration
statement has been signed below by the following persons in the capacities
indicated on May 6, 1999.
    
 
   
<TABLE>
<CAPTION>
                     SIGNATURE                                   TITLE                     DATE
                     ---------                                   -----                     ----
<C>                                                  <S>                              <C>
         (1) Principal Executive Officer:
                                                     President, Chief Executive
                         *                             Officer and Director           May 6, 1999
- ---------------------------------------------------
                  Barrett A. Toan
 
         (2) Principal Financial Officer:
                                                     Senior Vice President and
                         *                             Chief Financial Officer        May 6, 1999
- ---------------------------------------------------
                    George Paz
 
         (3) Principal Accounting Officer:           Vice President, Chief Accounting
                                                                                      May 6, 1999
                         *
- ---------------------------------------------------    Officer and Assistant Secretary
                  Joseph W. Plum
 
                  (4) Directors:
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                   Howard Atkins
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                Judith E. Campbell
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
              Richard M. Kernan, Jr.
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                Richard A. Norling
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
               Frederick J. Sievert
</TABLE>
    
 
                                      II-4
<PAGE>   127
 
   
<TABLE>
<CAPTION>
                     SIGNATURE                                   TITLE                     DATE
                     ---------                                   -----                     ----
<C>                                                  <S>                              <C>
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                Stephen N. Steinig
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                 Seymour Sternberg
 
                         *
- ---------------------------------------------------  Chairman, Director               May 6, 1999
                 Howard L. Waltman
 
                         *
- ---------------------------------------------------  Director                         May 6, 1999
                  Norman Zachary
 
             *By: /s/ KEITH J. EBLING
   ---------------------------------------------
            As attorney-in-fact for the
                  person indicated
</TABLE>
    
 
                                      II-5
<PAGE>   128
 
                                 EXHIBIT INDEX
 
   
<TABLE>
<CAPTION>
                                   DESCRIPTION                           PAGE
<S>   <C>  <C>                                                           <C>
 1.1   --  Form of Underwriting Agreement+.............................
 4.0   --  Certificate of Class A Common Stock*........................
 5.1   --  Opinion of Simpson Thacher & Bartlett+......................
23.1   --  Consent of PricewaterhouseCoopers LLP.......................
23.2   --  Consent of Ernst & Young LLP, Minneapolis, Minnesota........
23.3   --  Consent of Ernst & Young LLP, Pittsburgh, Pennsylvania......
           Consent of Simpson Thacher & Bartlett (included in Exhibit
23.4   --  5.1)+.......................................................
24.1   --  Powers of attorney++........................................
</TABLE>
    
 
- -------------------------
 
 * Incorporated by reference in our Registration Statement on Form 8-A dated May
   12, 1992.
 
 + To be filed by amendment.
 
   
++ Filed previously.
    

<PAGE>   1
 
                                                                    EXHIBIT 23.1
 
                       CONSENT OF INDEPENDENT ACCOUNTANTS
 
We hereby consent to:
 
     - the use in the Prospectus constituting part of this Registration
       Statement on Form S-3 of our report dated February 12, 1999 relating to
       the financial statements of Express Scripts, Inc. and our report dated
       February 26, 1999, except for Note 12, which is as of March 1, 1999,
       relating to the financial statements of Diversified Pharmaceutical
       Services, Inc. and subsidiary, which are included in such Prospectus;
 
     - the incorporation by reference in the Prospectus constituting part of
       this Registration Statement on Form S-3 of our report dated April 30,
       1998, on our audits of the combined financial statements of Value Health
       Pharmacy Benefit Management as of December 31, 1996, and for the years
       ended December 31, 1996 and 1995, appearing on page 24 of Express
       Scripts, Inc.'s Form 8-K/A Amendment No. 1 dated June 12, 1998; and
 
     - the references to us under the headings "Experts" and "Selected Financial
       and Operating Data" in such Prospectus. However, it should be noted that
       PricewaterhouseCoopers LLP has not prepared or certified such "Selected
       Financial and Operating Data."
 
PricewaterhouseCoopers LLP
St. Louis, Missouri
   
May 6, 1999
    

<PAGE>   1
 
                                                                    EXHIBIT 23.2
 
                          CONSENT OF ERNST & YOUNG LLP
 
   
     We consent to the reference to our firm under the caption "Experts" and to
the use of our reports dated June 4, 1998, with respect to the financial
statements of Value Health Pharmacy Benefit Management included in Express
Scripts, Inc.'s Current Report on Form 8-K/A dated June 12, 1998, and
incorporated by reference in this Registration Statement on Form S-3 and related
Prospectus of Express Scripts, Inc.
    
 
Minneapolis, Minnesota
   
May 6, 1999
    

<PAGE>   1
 
                                                                    EXHIBIT 23.3
 
                          CONSENT OF ERNST & YOUNG LLP
 
     We consent to the reference of our firm under the caption "Experts" and to
the
use of our reports dated June 1, 1998, with respect to the financial statements
of Managed Prescription Network, Inc. included in Express Scripts, Inc.'s
Current Report on Form
8-K/A dated June 12, 1998, and incorporated by reference in this Registration
Statement on Form S-3 and related Prospectus of Express Scripts, Inc.
 
Pittsburgh, Pennsylvania
   
May 6, 1999
    


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