EXPRESS SCRIPTS INC
S-8, EX-5.1, 2000-08-09
SPECIALTY OUTPATIENT FACILITIES, NEC
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                                   Exhibit 5.1

                       [Express Scripts, Inc. Letterhead]

                                 August 9, 2000

Express Scripts, Inc.
13900 Riverport Drive
Maryland Heights, Missouri 63043

Ladies and Gentlemen:

         I am Senior Vice  President,  General  Counsel and Secretary of Express
Scripts, Inc., a Delaware corporation (the "Company"), and in such capacity I am
familiar  with the  Registration  Statement on Form S-8 to which this opinion is
filed as an exhibit (the  "Registration  Statement"),  which registers under the
Securities Act of 1933, as amended (the "Securities  Act"),  2,000,000 shares of
Class A Common Stock,  par value $0.01,  of the Company (the "Shares")  reserved
for issuance pursuant to the Express Scripts, Inc. 2000 Long-Term Incentive Plan
(the "Plan").

         I have examined originals or copies, certified or otherwise, identified
to my satisfaction, of such documents, corporate records, certificates of public
officials and other  instruments  as I deemed  necessary for the purposes of the
opinion  expressed  herein. I have assumed (i) the genuineness of all signatures
on all  documents  examined  by  me,  (ii)  the  authenticity  of all  documents
submitted to me as originals, (iii) the conformity to authentic originals of all
documents  submitted to me as certified or photostatic  copies, and (iv) the due
authorization, execution and delivery of all documents.

         On the  basis  of the  foregoing,  I am of the  opinion  that  when the
Registration  Statement,  including any  amendments  thereto,  shall have become
effective  under  the  Securities  Act,  and the  Shares  have  been  issued  in
accordance  with the terms of the Plan,  then the Shares will be legally issued,
fully paid and nonassessable.

         This  opinion  is not  rendered  with  respect  to any laws  other than
federal laws and the General Corporation Law of the State of Delaware.  I do not
assume any duty to update this  opinion  with  respect to changes of law or fact
occurring after the date hereof.

         I  consent  to  the  filing  of  this  opinion  as an  exhibit  to  the
Registration  Statement. I also consent to your filing copies of this opinion as
an exhibit to the  Registration  Statement  with such agencies of such states as
you deem  necessary  in the  course of  complying  with the laws of such  states
regarding the offering and sale of the Shares. In giving this consent,  I do not
admit that I am in the  category  of persons  whose  consent is  required  under
Section 7 of the Securities  Act or the rules and  regulations of the Securities
and Exchange Commission.


                              Very truly yours,

                             /S/ Thomas M. Boudreau

                             Thomas M. Boudreau
                             Senior Vice President,
                             General Counsel and Secretary



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