TEXAS BIOTECHNOLOGY CORP /DE/
8-K, 1999-09-14
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                   ------------------------------------------



                                    FORM 8-K



                                 CURRENT REPORT


                       Pursuant to Section 13 or 15(d) of
                    the Securities and Exchange Act of 1934

 Date of Report: (Date of earliest event reported):
                                        September 14, 1999 (September 10, 1999)


                        TEXAS BIOTECHNOLOGY CORPORATION
             (Exact name of registrant as specified in its charter)



     DELAWARE                     1-12574                     13-3532643
  --------------                ------------               -------------------
    (State of                   (Commission                  (IRS Employer
  Incorporation)                File Number)               Identification No.)


                            7000 FANNIN, SUITE 1920
                              HOUSTON, TEXAS 77030
             (Address of Registrant's principal executive offices)

                                 (713) 796-8822
              (Registrant's telephone number, including area code)




                                (NOT APPLICABLE)
         (Former name or former address, if changed since last report)


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ITEM 5.              OTHER EVENTS

           On September 10, 1999, Texas Biotechnology Corporation (the
"Company") and the Bank of New York amended the Warrant Agreement, dated as of
December 15, 1993 (the "Warrant Agreement"), relating to the Company's
redeemable common stock purchase warrants (CUSIP No. 8822IT120) (the
"Warrants"). The Warrant Agreement was amended solely to extend the expiration
date of the Warrants from September 30, 1999 to December 31, 2000.

           The Warrants trade on the American Stock Exchange under the symbol
"TXBWS." The press release and the amendment to the Warrant Agreement are filed
as exhibits hereto.

ITEM 7.           FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION
                  AND EXHIBITS

           (C)    EXHIBITS


                     4.1   Second Amendment to Warrant Agreement
                    99.1   Press Release dated September 13, 1999.




                                       2

<PAGE>   3



                                   SIGNATURES

           Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

Date:      September 14, 1999       TEXAS BIOTECHNOLOGY CORPORATION



                                    /s/ Stephen L. Mueller
                                    -------------------------------------------
                                    Vice President, Finance and Administration,
                                    Secretary and Treasurer


                                       3

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                               INDEX TO EXHIBITS


          EXHIBIT                   DESCRIPTION OF EXHIBIT
          -------        ------------------------------------------
            4.10         Second Amendment to Warrant Agreement.
           99.1          Press Release, dated September 13, 1990.




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                                                                   EXHIBIT 4.10

                     SECOND AMENDMENT TO WARRANT AGREEMENT


           This SECOND AMENDMENT TO WARRANT AGREEMENT (the "Amendment"), dated
as of September 10, 1999, is entered into by and between Texas Biotechnology
Corporation, a Delaware corporation (the "Company") and The Bank of New York, a
corporation organized under the banking laws of the State of New York (the
"Warrant Agent").

                              W I T N E S S E T H


           WHEREAS, the Company and the Warrant agent are parties to the
Warrant Agreement dated as of December 15, 1993, (the "Warrant Agreement"),
pursuant to which the Warrant Agent acts on behalf of the Company in connection
with the issuance, transfer, exchange, replacement, redemption and surrender of
the certificates for the Company's Redeemable Common Stock Purchase Warrants
(the "Warrants");

           WHEREAS, the Company has requested and the Warrant Agent agrees to
certain amendments to the Warrant Agreement; and

           WHEREAS, the Warrant Agent is willing to amend the Warrant
Agreement, subject to the terms and conditions of this Amendment.

           NOW THEREFORE, in consideration of the premises and other good and
valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the parties agree as follows:

           1. Defined Terms. Unless otherwise defined herein capitalized terms
used herein shall have the meanings, if any, assigned to them in the Warrant
Agreement.

           2.        Amendment to Warrant Agreement.

                     Section 2.2 of the Warrant Agreement is hereby amended
and restated in its entirety to read as follows:

                     "2.2 Registration of Common Stock and Exercisability of
           Warrants. Each Warrant may be exercised at any time on or after
           December 15, 1993, the effective date of the Offering, as long as
           the effectiveness of the registration of the Warrant Shares is
           maintained under the Securities Act of 1933, as amended (the
           "Securities Act"), but not after 5:00 P.M., New York City time, on
           the earlier of December 31, 2000, unless extended by the Company and
           the Warrant Agent, or the business day immediately preceding the
           Call Date (as defined in Section 4.11). The term "Exercise Deadline"
           as used in this Agreement shall mean the latest time and date at
           which the Warrants may be exercised. The Company shall use its best
           efforts to maintain the



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           registration or qualification in effect of the Warrant Shares and to
           keep available for delivery upon the exercise of the Warrants a
           prospectus that meet the requirements of Section 10 of the
           Securities Act, until the earlier of the date by which all Warrants
           are exercised or the Exercise Deadline; provided, however, that the
           Company shall have no obligation hereunder to maintain the
           effectiveness of such registration or qualification ro keep
           available a prospectus, as aforesaid, in the event that, by
           amendment to the Securities Act or otherwise, such registration or
           qualification or the delivery of such prospectus is not required at
           the said Common Stock is to be issued; and provided further, that in
           the event, by amendment to the Securities Act or otherwise, some
           other or different requirement shall be imposed by act of the
           Congress of the United States which shall related to the issuance of
           Common Stock upon exercise of the Warrants, the Company shall use
           its best efforts to comply with such requirements."

           3. Representations and Warranties. The Company hereby represents and
warrants to the Warrant Agent as follows:

                     The execution, delivery and performance by the Company of
           this Amendment has been duly authorized by all necessary corporate
           and other action and does not, and will not, require any
           registration, with consent or approval of, notice to or action by,
           any person or entity (including any governmental authority or
           entity) in order to be effective and enforceable. The Warrant
           Agreement, including such provisions that have been amended by this
           Amendment, constitute the legal, valid and binding obligations of
           the Company.

           4. Effective Date. This amendment will become effective as of
September 10, 1999 (the "Effective Date"); provided that each of the following
conditions precedent is satisfied:

           (a)       The Company has executed and delivered this Amendment; and

           (b) All representations and warranties contained herein are true and
           correct as of the Effective Date.

           5.        Miscellaneous.

           (a) Except as expressly amended or waived herein, all terms,
           covenants and provisions of the Warrant Agreement and the other
           documents executed in connection thereto are and shall remain in
           full force and effect.

           (b) This Amendment shall be binding upon and inure to the benefit of
           the parties hereto and their respective successors and assigns.


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           (c) This Amendment may be executed in one or more counterparts, each
           of which shall be deemed an original, but all of which together
           shall constitute one and the same instrument.

           (d) This Amendment, together with the Warrant Agreement and the
           other documents executed in connection thereto, embodies the final,
           entire agreement among the parties hereto and supersedes any and all
           prior commitments or agreements in connection with the subject
           matter thereof, representations and understandings, whether written
           or oral, relating to the subject matter hereof and may not be
           contradicted or varied by evidence of prior, contemporaneous, or
           subsequent oral agreements or discussions of the parties hereto.
           There are no unwritten oral agreements among the parties hereto.


           IN WITNESS WHEREOF, the parties hereto have executed and delivered
this Amendment as of the date first above written.

                                      TEXAS BIOTECHNOLOGY CORPORATION


                                      By:  /s/ STEPHEN L. MUELLER
                                         -------------------------------------
                                      Name:  Stephen L. Mueller
                                      Title:  Vice President & Administration



                                      THE BANK OF NEW YORK


                                      By:  /s/ JAMES DIMINO
                                         -------------------------------------
                                      Name:  James Dimino
                                      Title:  Vice President


                                       3


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Contact:  Pamela M. Murphy Vice President,
          Corporate Communications
          Texas Biotechnology Corporation
          (713) 796-8822 x107



                        TEXAS BIOTECHNOLOGY CORPORATION
                                EXTENDS WARRANTS

HOUSTON, TX - SEPTEMBER 13, 1999 - Texas Biotechnology Corporation (AMEX:TXB)
announced that the exercise deadline for its Redeemable Common Stock Purchase
Warrants (the "Warrants") has been extended from 5:00 PM, eastern standard
time, on September 30, 1999 to 5:00 PM December 31, 2000. The strike price for
the Warrants remains $8.44.

Any questions regarding the extension of the exercise deadline or the exercise
of the Warrants may be directed to:

                              The Bank of New York
                           Reorganization Department
                                  800/507-9357

Texas Biotechnology is a biopharmaceutical company focused on the development
and commercialization of small molecule drugs to treat a variety of diseases
including thrombosis, chronic heart failure and asthma.

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