CELLEGY PHARMACEUTICALS INC
10QSB, 1998-05-08
PHARMACEUTICAL PREPARATIONS
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                                   FORM 10-QSB


                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549


[X]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
                                   ACT OF 1934


For the quarterly period ended March 31, 1998

                                       OR

[ ]  TRANSITION  REPORT  PURSUANT  TO  SECTION  13 OR  15(d)  OF THE  SECURITIES
                              EXCHANGE ACT OF 1934

For the transition period from                     to

Commission File Number:  0-26372


                          CELLEGY PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)


         California                                             82-0429727
(State or other jurisdiction of                              (I.R.S. Employer
incorporation or organization)                            Identification Number)


     1065 East Hillsdale Boulevard, Suite 418, Foster City, California 94404
          (Address of principal executive offices, including zip code)
                           

                                 (650) 524-1600
              (Registrant's telephone number, including area code)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by  Sections  13 or 15(d)  of the  Securities  Exchange  Act of 1934
during the preceding 12 months (or for such shorter  period that the  registrant
was  required  to file such  reports),  and (2) has been  subject to such filing
requirements for the past 90 days.    Yes X    No
                                         ---     ---

The number of shares  outstanding of the registrant's  common stock at April 29,
1998 was 10,165,315.


<PAGE>


                          CELLEGY PHARMACEUTICALS, INC.

                              INDEX TO FORM 10-QSB


                                                                            Page
                                                                            ----
PART I     FINANCIAL INFORMATION

Item 1.    Financial Statements

           Condensed Balance Sheets as of March 31, 1998 (unaudited) and
           December 31, 1997 ................................................  3

           Unaudited  Condensed  Statements of Operations  for the three
           months  ended  March 31,  1998 and 1997,  and the period from
           June 26, 1989 (inception) through March 31, 1998 .................  4

           Unaudited  Condensed  Statements  of Cash Flows for the three
           months  ended  March 31,  1998 and 1997,  and the period from
           June 26, 1989 (inception) through March 31, 1998 .................  5

           Notes to Condensed Financial Statements ..........................  7

Item 2.    Management's  Discussion and Analysis of Financial  Condition
           and Results of Operations ........................................  8

PART II    OTHER INFORMATION

Item 1.    Legal Proceedings ................................................ 11

Item 2.    Changes in Securities ............................................ 11

Item 3.    Defaults Upon Senior Securities .................................. 11

Item 4.    Submission of Matters to a Vote of Security Holders .............. 11

Item 5.    Other Information ................................................ 11

Item 6.    Exhibits and Reports on Form 8-K ................................. 11

Signature(s) ................................................................ 12


<PAGE>


<TABLE>
                                                   PART I - FINANCIAL INFORMATION


Item 1.  Financial Statements

                                                    Cellegy Pharmaceuticals, Inc.
                                                    (a development stage company)

                                                      Condensed Balance Sheets

                                            (Amounts in thousands, except share amounts)
<CAPTION>

                                                                                                  March 31, 1998   December 31, 1997
                                                                                                  --------------   -----------------
                                                                                                    (Unaudited)
<S>                                                                                                   <C>               <C>     
Assets
Current assets:
     Cash and cash equivalents ..............................................................         $  1,508          $  1,822
     Short-term investments .................................................................            5,224             7,482
     Other current assets ...................................................................              855             1,011
                                                                                                      --------          --------
Total current assets ........................................................................            7,587            10,315
Property and equipment, net .................................................................               13                14
Long-term investments .......................................................................           13,432            12,422
                                                                                                      --------          --------
Total assets ................................................................................         $ 21,032          $ 22,751
                                                                                                      ========          ========

Liabilities and Shareholders' Equity
Current liabilities:
     Accounts payable and accrued liabilities ...............................................              410               705
     Deferred revenue .......................................................................              250               500
     Accrued research fees ..................................................................             --                 155
     Accrued compensation and related expenses ..............................................               49                37
                                                                                                      --------          --------
Total current liabilities ...................................................................              709             1,397

Shareholders' equity:
     Common stock, no par value; 20,000,000 shares authorized: 10,165,015 shares
         issued and outstanding at March 31, 1998 and 10,123,751 shares issued
         and outstanding at December 31, 1997 ...............................................           44,353            44,192
     Accumulated other comprehensive income (loss) ..........................................               64               (12)
     Deficit accumulated during the development stage .......................................          (24,094)          (22,826)
                                                                                                      --------          --------
     Total shareholders' equity .............................................................           20,323            21,354
                                                                                                      --------          --------
Total liabilities and shareholders' equity ..................................................         $ 21,032          $ 22,751
                                                                                                      ========          ========

                                                                                                 
<FN>

The  accompanying  notes  are an  integral  part of  these  condensed  financial statements.
</FN>
</TABLE>

                                                                  3
<PAGE>


<TABLE>
                                                    Cellegy Pharmaceuticals, Inc.
                                                    (a development stage company)

                                                 Condensed Statements of Operations

                                                             (Unaudited)
                                          (Amounts in thousands, except per share amounts)
<CAPTION>

                                                                                                                        Period from
                                                                                                                       June 26, 1989
                                                                                                                         (inception)
                                                                                  Three Months Ended March 31,             through
                                                                                -------------------------------            March 31,
                                                                                    1998                1997                 1998
                                                                                -----------         -----------          -----------
<S>                                                                             <C>                 <C>                  <C>       
Revenues:
     Licensing and contract revenue from affiliate .....................        $      --           $      --            $    1,145
     Licensing, milestone, and development funding .....................                 62                  95               1,225
     Government grants .................................................                 53                  53                 351
                                                                                -----------         -----------          -----------
Total revenues .........................................................                115                 148               2,721
Operating expenses:
     Research and development ..........................................              1,182                 734              14,091
     General and administrative ........................................                519                 360               8,309
     Acquired in process technology ....................................               --                  --                 3,843
                                                                                -----------         -----------          -----------
Total operating expenses ...............................................              1,701               1,094              26,243
                                                                                -----------         -----------          -----------
Operating loss .........................................................             (1,586)               (946)            (23,522)
     Interest expense ..................................................               --                  --                  (864)
     Interest income and other, net ....................................                318                  79               1,740
                                                                                -----------         -----------          -----------
Net loss ...............................................................             (1,268)               (867)            (22,646)
Non-cash preferred dividends ...........................................               --                    26               1,448
                                                                                ===========         ===========          ===========
Net loss applicable to common shareholders .............................        $    (1,268)        $      (893)         $  (24,094)
                                                                                ===========         ===========          ===========
Basic and diluted net loss per common share ............................        $     (0.13)        $     (0.17)
                                                                                ===========         ===========                     
Weighted average common shares outstanding .............................             10,143               5,377
                                                                                ===========         ===========                     


<FN>
The  accompanying  notes  are an  integral  part of  these  condensed  financial statements.
</FN>
</TABLE>

                                                                  4

<PAGE>



<TABLE>
                                                    Cellegy Pharmaceuticals, Inc.
                                                    (a development stage company)

                                                 Condensed Statements of Cash Flows

                                                             (Unaudited)
                                                       (Amounts in thousands)
<CAPTION>

                                                                                                                         Period from
                                                                                                                       June 26, 1989
                                                                                                                        (inception)
                                                                                         Three Months Ended March 31,     through
                                                                                         ----------------------------     March 31,
                                                                                               1998           1997           1998
                                                                                             --------       --------       --------
<S>                                                                                          <C>            <C>             <C>     
Operating activities
Net loss ..............................................................................      $ (1,268)      $   (867)      $(22,646)
Adjustment to reconcile net loss to net cash used in operating activities:
   Acquired in process technology .....................................................          --             --            3,843
   Depreciation and amortization ......................................................             1              6            266
   Compensation expense related to the extension of option
     exercise periods .................................................................          --               70            338
   Loss on sale of property and equipment .............................................          --             --                4
   Amortization of discount on notes payable and deferred
     financing costs ..................................................................          --             --              568
   Issuance of common shares for services .............................................          --             --               24
   Issuance of Series A convertible preferred stock for
     services rendered ................................................................          --             --               73
   Issuance of Series A convertible preferred stock for interest ......................          --             --               68
   Issuance of Series A convertible preferred stock for license
     agreement ........................................................................          --             --              100
Changes in operating assets and liabilities:
   Other current assets ...............................................................           156              6           (855)
   Accounts payable and accrued liabilities ...........................................          (295)           (53)           410
   Accrued research fees ..............................................................          (155)           (21)          --
   Accrued compensation and related expenses ..........................................            12             (5)            49
   Deferred revenue ...................................................................          (250)          --              250
                                                                                             --------       --------       --------
Net cash used in operating activities .................................................        (1,799)          (864)       (17,508)

Investing activities
Purchase of property and equipment ....................................................          --             --             (173)
Purchases of investments ..............................................................        (3,000)        (1,000)       (38,539)
Sales and maturities of investments ...................................................         4,324          1,900         19,946
                                                                                             --------       --------       --------
Net cash used in investing activities .................................................         1,324            900        (18,766)

<FN>
                                                      (continued on next page)

The accompanying notes are an integral part of these condensed financial statements.
</FN>
</TABLE>

                                                                 5

<PAGE>


<TABLE>
                                                    Cellegy Pharmaceuticals, Inc.
                                                    (a development stage company)

                                          Condensed Statements of Cash Flows - (Continued)

                                                             (Unaudited)
                                                       (Amounts in thousands)

<CAPTION>
                                                                                                                        Period from
                                                                                                                       June 26, 1989
                                                                                                                         (inception)
                                                                                       Three Months Ended March 31,        through
                                                                                       ----------------------------        March 31,
                                                                                          1998              1997             1998
                                                                                       ----------        ----------        --------
<S>                                                                                    <C>               <C>                    <C>
Financing activities
Proceeds from notes payable ...................................................        $     --          $     --          $  3,547
Repayment of notes payable ....................................................              --                --            (2,111)
Net proceeds from issuance of common stock ....................................               161                19          24,668
Issuance of convertible preferred stock, net of issuance costs ................              --                --            11,758
Deferred financing costs ......................................................              --                --               (80)
                                                                                       ----------        ----------        --------
Net cash provided by financing activities .....................................               161                19          37,782
                                                                                       ----------        ----------        --------
Net increase (decrease) in cash and cash equivalents ..........................              (314)               55           1,508
Cash and cash equivalents, beginning of period                                              1,822                36            --
                                                                                       ----------        ----------        --------
Cash and cash equivalents, end of period ......................................        $    1,508        $       91        $  1,508
                                                                                       ==========        ==========        ========
Supplemental disclosure of non-cash transactions:
Issuance of common stock in connection with acquired in process
   technology .................................................................        $     --          $     --          $  3,843
                                                                                       ==========        ==========        ========
Conversion of preferred stock to common stock .................................        $     --          $    1,623        $ 14,715
                                                                                       ==========        ==========        ========
Issuance of common stock for notes payable ....................................        $     --          $     --          $    269
                                                                                       ==========        ==========        ========
Issuance of warrants in connection with notes payable financing ...............        $     --          $     --          $    487
                                                                                       ==========        ==========        ========
Issuance of Series A convertible preferred stock for notes
   payable ....................................................................        $     --          $     --          $  1,153
                                                                                       ==========        ==========        ========
Issuance of Series B convertible preferred stock for notes
   payable ....................................................................        $     --          $     --          $    115
                                                                                       ==========        ==========        ========
Issuance of common stock for Pacific Pharmaceuticals, Inc. ....................        $     --          $     --          $      9
                                                                                       ==========        ==========        ========

<FN>
The accompanying notes are an integral part of these condensed financial statements.
</FN>
</TABLE>

                                                                 6

<PAGE>


                          Cellegy Pharmaceuticals, Inc.
                          (a development stage company)

                     Notes to Condensed Financial Statements

Note 1.   -   Basis of Presentation

         The  accompanying  interim  condensed  financial  statements  have been
prepared  by the  Company  in  accordance  with  generally  accepted  accounting
principles for interim  financial  information and with the instructions to Form
10-QSB and Item 310(b) of Regulation S-B.  Accordingly,  they do not include all
of the  information  and footnote  disclosures  required by  generally  accepted
accounting  principles  for  complete  financial  statements.   These  condensed
financial  statements should be read in conjunction with the Company's financial
statements  and notes thereto  contained in the Company's  Annual Report on Form
10-KSB for the year ended December 31, 1997. In the opinion of  management,  the
accompanying condensed financial statements include all adjustments  (consisting
of  only  normal  recurring   adjustments)   considered  necessary  for  a  fair
presentation  of financial  position and results of  operations  for the periods
presented.

         Operating  results  for the three  months  ended March 31, 1998 may not
necessarily  be  indicative  of the results to be expected for any other interim
period or for the full year.

Note 2.   - Basic and Diluted Net Loss per Share

         The financial  statements are presented in accordance with Statement of
Financial Accounting Standards No. 128, "Earnings per Share." Basic net loss per
common share is computed  using the  weighted  average  number of common  shares
outstanding  during the period.  Diluted  earnings  per share  incorporates  the
incremental  shares  issued  upon the  assumed  exercise  of stock  options  and
warrants,  when dilutive.  There is no difference  between basic and diluted net
loss per share, as presented in the statement of operations, because all options
and warrants are anti-dilutive.

Note 3.   -   Comprehensive Income

         The Company has adopted  Statement  of Financial  Accounting  Standards
("SFAS") No. 130, "Reporting  Comprehensive  Income," as of the first quarter of
1998.  SFAS No.  130  establishes  new rules for the  reporting  and  display of
comprehensive  income  and  its  components.  It has no  impact  on net  loss or
stockholders' equity.

         The components of comprehensive income are as follows:

                             (in thousands)
                                                    Three Months Ended March 31,
                                                    ----------------------------
                                                      1998            1997
                                                     -------        -------
Net loss                                             $(1,268)       $  (893)
Change in unrealized gain (loss) on
  available-for-sale investments                          76             (9)
                                                     -------        -------
Comprehensive net loss                               $(1,192)       $  (902)
                                                     =======        =======

         Accumulated  other   comprehensive   income  (loss)  presented  on  the
accompanying  balance sheet  consists of the  accumulated  net  unrealized  gain
(loss) on available-for-sale investments.

                                       7

<PAGE>


Note 4.   -   Subsequent Event

         In April 1998, the Company signed an agreement to lease a new facility,
currently under construction,  in the proximity of its current  facilities.  The
lease term is for ten years.  The facility size is  approximately  65,000 square
feet, of which a significant portion may be sublet by Cellegy during its initial
years  of  occupancy.  The  Company  plans to  consolidate  its  laboratory  and
administrative operations into the new facility by the end of this year or early
in 1999.


Item 2.  Management's Discussion and Analysis of Financial Condition and Results
         of Operations

     This Quarterly Report on Form 10-QSB, includes forward-looking  statements.
Words  such as  "believes,"  "anticipates,"  "expects,"  "intends"  and  similar
expressions are intended to identify forward-looking statements, but are not the
exclusive means of identifying such statements. These forward-looking statements
concern  matters that involve  risks and  uncertainties  that could cause actual
results  to differ  materially  from  those in the  forward-looking  statements.
Further,  the Company  undertakes no  obligation  to revise any  forward-looking
statements in order to reflect events or circumstances  that may arise after the
date of this report.  Actual events or results may differ  materially from those
discussed in this Quarterly Report.

     Cellegy Pharmaceuticals, Inc. is a biopharmaceutical company engaged in the
development of  prescription  drugs and  cosmeceuticals  to address a variety of
diseases and conditions  utilizing its patented transdermal and topical delivery
technologies.  The Company was  incorporated  in California in 1989.  Cellegy is
developing   several    prescription    drugs,    including    Anogesic(R),    a
nitroglycerin-based  product for the treatment of anal fissures and hemorrhoids,
and a  transdermal  testosterone  gel  for  the  treatment  of  hypogonadism,  a
condition  that  frequently  results in lethargy and reduced libido in men above
the age of 40. In addition  to its  prescription  drugs,  Cellegy is testing and
developing a line of  anti-wrinkling  cosmeceutical  products  which the Company
believes will address the skin care needs of an affluent and aging population.

General

     In November 1997, the Company  completed a $15.1 million public offering of
approximately  2.0 million shares of Common Stock.  CIBC Oppenheimer Corp. acted
as underwriter in connection  with the offering.  Simultaneously,  the Company's
stock was approved for listing on the Nasdaq National Market.

     In December  1997, the Company  completed an asset purchase  agreement with
Neptune Pharmaceutical  Corporation  ("Neptune") to acquire all patent and other
intellectual  property rights relating to Anogesic,  a topical product candidate
for the  treatment of anal  fissures and  hemorrhoids.  The  Company's  expenses
relating to product  development  and  clinical  trials are expected to increase
during 1998 and thereafter as a result of clinical  trial  expenses  relating to
Anogesic.  Although the purchase price for Anogesic is payable in Cellegy Common
Stock,  the  Company  recorded a non-cash  charge to  operations  for in process
technology of $3,843,000 upon completion of the Anogesic acquisition in 1997.

     During the first quarter of 1998, the Company  finalized the clinical trial
plans with the FDA for Anogesic.  Cellegy plans to initiate the clinical  trials
for the treatment of anal fissures by the third quarter of 1998.

                                       8

<PAGE>


Results of Operations

     Revenues.  The Company had  revenues of $115,000 and $148,000 for the three
months  ended March 31,  1998 and 1997,  respectively.  During the three  months
ended March 31,  1998,  revenues  consisted of $62,000 for  development  funding
associated  with the Glaxo license  agreement  and $53,000  related to an Orphan
Drug grant from the FDA to cover certain of the Company's  clinical  trial costs
for Glylorin.  During the first quarter of 1997,  revenues  consisted of $95,000
associated  with the Glaxo  license  agreement  and $53,000 from FDA Orphan Drug
grant  payments.  The Company  expects to receive  lower  levels of  development
funding  from  Glaxo  over the next  several  quarters,  but is  pursuing  other
licensing and product supply  agreements  which,  if entered into, may result in
additional  contract  revenues  or  product  sales.  There can be no  assurances
regarding  when, or if, such revenues will occur.  Through the end of the Orphan
Drug  grant  period on  September  30,  1998,  the  Company  expects  to receive
approximately $40,000 in FDA Orphan Drug grant funding.

     Research and Development  Expenses.  Research and development expenses were
$1,182,000 for the three months ended March 31, 1998, compared with $734,000 for
the same period last year.  The increase of $448,000 was primarily due to salary
costs in connection  with  increased  scientific  personnel  and the  associated
recruiting  and  relocation  expenses,  as well as increased  contract  research
expenses.  Cellegy's  research  expenses  are  expected  to continue to increase
during 1998 as  preclinical  and clinical  trial  activity  associated  with its
Anogesic, transdermal testosterone gel and anti-wrinkling programs increases and
as it continues  to focus on the  development  of the  Company's  drug  delivery
technologies. The Company plans to accelerate hiring in research and development
in order to accomplish its goals.

     General and Administrative  Expenses.  General and administrative  expenses
increased to $519,000 for the three months ended March 31, 1998,  compared  with
$360,000  for the same period last year.  This  increase  was  primarily  due to
salary costs in connection with the addition of administrative personnel and the
associated   recruiting  expenses,  as  well  as  increased  external  reporting
expenses.  The  Company's  general and  administrative  expenses are expected to
increase in the future in support of its research and product  commercialization
efforts, particularly associated with the launch of its cosmeceuticals,  and the
planned expansion and consolidation of its office and laboratory facilities.

     Interest Income and Expense. The Company earned $318,000 in interest income
for the three months ended March 31,  1998,  compared  with $79,000 for the same
period last year. The additional interest income earned during the first quarter
of 1998  was  due to  higher  average  investment  balances  during  the  period
resulting from proceeds  associated with a private  placement in July 1997 and a
public  offering of Common  Stock in  November  1997.  No  interest  expense was
incurred  during the three  months  ended March 31, 1998 or 1997.  However,  the
Company  may incur such  expenses  in future  periods  associated  with a tenant
improvement loan planned for its facility expansion.

     Net Loss. The net loss applicable to common  shareholders was $1,268,000 or
$0.13 per share for the three  months  ended March 31, 1998 based on  10,143,000
weighted  average  shares  outstanding,  compared with a net loss of $893,000 or
$0.17 per share for the same period in the prior year,  when 5,377,000  weighted
average shares were outstanding.

                                       9

<PAGE>


Liquidity and Capital Resources

     The  Company  has  experienced  net  losses  and  negative  cash  flow from
operations  each year since its  inception.  Through March 31, 1998, the Company
had incurred an accumulated  deficit of $24.1 million and had consumed cash from
operations of $17.5  million.  The  Company's  public  financings  included $6.4
million in net proceeds from its initial  public  offering in August 1995,  $6.8
million in net proceeds  from a preferred  stock  financing in April 1996,  $3.8
million in net proceeds  from a private  placement of Common Stock in July 1997,
and $13.8  million in net proceeds for a secondary  public  offering in November
1997.

     The Company's  cash and  investments  were $20.2 million at March 31, 1998,
compared  with $21.7  million at December  31,  1997.  The  decrease in cash and
investments was principally due to net cash used in operating activities.

     The Company's  operations have and will continue to use substantial amounts
of cash. The Company has no current source of  significant  ongoing  revenues or
capital beyond existing cash and investments.  In order to complete the research
and development and other activities  necessary to  commercialize  its products,
additional  financing may be required.  The Company's  future  expenditures  and
capital  requirements depend on numerous factors including,  without limitation,
the progress and focus of its research and  development  programs,  the progress
and results of preclinical and clinical testing,  the time and costs involved in
obtaining  regulatory  approvals  and  complying  with  pre-  and  post-approval
regulatory  requirements,  the  costs  of  filing,  prosecuting,  defending  and
enforcing any patent claims and other  intellectual  property rights,  competing
technological  and  market  developments,  changes  in  the  Company's  existing
research  relationships,  the ability of the Company to establish  collaborative
arrangements,  the initiation of commercialization  activities,  the purchase of
capital equipment and the availability of other financing.

     In the course of its  development  activities,  the  Company  has  incurred
significant  losses and  expects  to incur  substantial  additional  development
costs.  As a result,  the  Company  will  require  additional  funds to  finance
operations  and may  seek  private  or  public  equity  investments  and  future
collaborative  arrangements  with third parties to meet such needs.  There is no
assurance  that such funding  will be  available  for the Company to finance its
operations on acceptable terms, if at all.  Insufficient funding may require the
Company  to  delay,  reduce  or  eliminate  some  or  all of  its  research  and
development activities, planned clinical trials and administrative programs. The
Company  believes that available cash resources and the interest thereon will be
adequate to satisfy its capital needs through at least December 31, 1999.

Factors That May Affect Future Operating Results

     This Quarterly  Report on Form 10-QSB contains  forward-looking  statements
which involve risks and uncertainties, including, but not limited to, statements
concerning the  commencement  and completion of clinical  trials,  the timing of
planned  regulatory  filings,  the  applicability  of drug and cosmetic laws and
regulations  to the Company's  products,  planned  activities  of  collaborative
partners,  the Company's  strategic  plans,  the scope of the  Company's  patent
coverage,  anticipated  expenditures  and the need  for  additional  funds.  The
factors  discussed  in the  Company's  reports  filed  with the  Securities  and
Exchange  Commission,  including the Company's  Annual Report on Form 10-KSB for
the year ended December 31, 1997, in particular  under the caption "Factors That
May Affect  Future  Operating  Results,"  should be  carefully  considered  when
evaluating the Company's business and prospects.

                                       10

<PAGE>


                           PART II - OTHER INFORMATION

Item 1.           Legal Proceedings

         None

Item 2.           Changes in Securities

         None

Item 3.           Defaults Upon Senior Securities

         None

Item 4.           Submission of Matters to a Vote of Security Holders

         None

Item 5.           Other Information

         None

Item 6.           Exhibits and Reports on Form 8-K

         (a)      Exhibits

        Exhibit 10.01       Lease agreement dated April 8, 1998

         (b)      Reports on Form 8-K

         On November 3, 1997, the Company signed a letter of intent with Neptune
Pharmaceutical  Corporation  to acquire  all patent  and  intellectual  property
rights relating to "Anogesic",  a topical product candidate for the treatment of
anal  fissures and  hemorrhoids.  This event was reported on a Form 8-K filed on
November 12, 1997. The final  purchase  agreement for this product was signed on
December  31,  1997.  This  product  acquisition  was  reported on a Form 8-K on
January 14, 1998.

                                       11

<PAGE>


                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


                                                   CELLEGY PHARMACEUTICALS, INC.


Date:  May 8, 1998                          /s/    K. Michael Forrest
                                            ------------------------------------
                                                   K. Michael Forrest
                                                   President and Chief Executive
                                                   Officer


Date:  May 8, 1998                          /s/    A. Richard Juelis
                                            ------------------------------------
                                                   A. Richard Juelis
                                                   Vice President, Finance and
                                                   Chief Financial Officer



                            BASIC LEASE INFORMATION

LEASE DATE:                       April 8, 1998

TENANT:                           CELLEGY PHARMACEUTICALS, INC.

TENANT'S ADDRESS:                 Until the Term Commencement  Date:

                                  1065 E. Hillsdale Blvd., Suite 418
                                  Foster City, CA 94404
                                  Phone: (650)524-1600
                                  Fax:   (650)524-1616

                                  After the Term Commencement Date:

                                  349 Oyster Point Blvd.
                                  South San Francisco, CA 94080

LANDLORD:                         TC Northern California, Inc.

LANDLORD'S ADDRESS:               1241 East Hillsdale Blvd., Ste. 200
                                  Foster City, CA  94404
                                  Phone: (650)578-8100
                                  Fax:   (650)345-2506

PROJECT:                          A   two   (2)   building    project   totaling
                                  approximately   105,000   square  feet  to  be
                                  constructed  on  approximately  5.52  acres of
                                  land to be known as 347 and 349  Oyster  Point
                                  Blvd.,  South San Francisco,  California 94080
                                  which legal description is contained herein in
                                  Exhibit A-1.

BUILDING:                         That  approximately  65,000  square  foot  two
                                  story  building to be  constructed  as part of
                                  the  Project  and to be  known  as 349  Oyster
                                  Point   Boulevard,    South   San   Francisco,
                                  California 94080, as approximately depicted on
                                  the site plan attached as Exhibit A-2.

PREMISES:                         The  Building to be known as 349 Oyster  Point
                                  Boulevard,  South  San  Francisco,  California
                                  94080

PERMITTED USE:                    Office,  laboratory,  research and development
                                  facility, with wet chemistry and biology labs,
                                  clean rooms,  clinical GMP  manufacturing  and
                                  manufacturing of  pharmaceutical  and cosmetic
                                  products,   storage   and  use  of  toxic  and
                                  radioactive  materials and laboratory  animals
                                  used  in  Tenant's  business  (subject  to the
                                  approval  of the City of South  San  Francisco
                                  and all other necessary government  agencies),
                                  and  other   related  legal  uses  subject  to
                                  Landlord's   approval   which   shall  not  be
                                  unreasonably withheld.

PARKING DENSITY:                  3.5 non-exclusive  spaces per 1000 square feet
                                  of rentable area

ESTIMATED TERM COMMENCEMENT DATE: November 1, 1998

LENGTH OF TERM:                   One Hundred Twenty (120) months

<TABLE>
RENT:
<CAPTION>
       Base Rent                  Months of Term     Rent Per Square Foot       Monthly Rent
                                  --------------     --------------------       ------------
<S>                                                  <C>                        <C>
                                  Months 1-3         $1.45 psf per month        $  47,125
                                                     (rent on 32,500 sf)
                                  Months 4-12        $1.45 (rent on 65,000 sf)  $  94,250
                                  Months 13-24       $1.49 (rent on 65,000 sf)  $  97,078
                                  Months 25-36       $1.54 (rent on 65,000 sf)  $  99,990
                                  Month 37-48        $1.58 (rent on 65,000 sf)  $ 102,990
                                  Month 49-60        $1.63 (rent on 65,000 sf)  $ 106,079
                                  Month 61-72        $1.68 (rent on 65,000 sf)  $ 109,262
                                  Month 73-84        $1.73 (rent on 65,000 sf)  $ 112,539
                                  Month 85-96        $1.78 (rent on 65,000 sf)  $ 115,916
                                  Month 97-108       $1.84 (rent on 65,000 sf)  $ 119,393
                                  Month 109-120      $1.89 (rent on 65,000 sf)  $ 122,975
</TABLE>

Estimated First Year Basic
Operating Cost                    $.30 psf per month, estimated at $19,500/mo.

SECURITY DEPOSIT:                 $227,500,  plus secured first lien on Tenant's
                                  fixtures and improvements

TENANT'S PROPORTIONATE SHARE:     Subject to change,  but based on the  rentable
                                  square  feet of the  Premises  divided  by the
                                  total rentable square feet of the Building and
                                  the   Project,   respectively,   estimated  as
                                  follows:

                                        Of Building:              100 %
                                        Of Project                61.9 %

BROKER:  R. Randy Scott                    Dean Givas
         Cornish & Carey Commercial        Trammell Crow NW, Inc.
         245 Lytton Avenue, Ste 150        1241 East Hillsdale Blvd., Suite 200
         Palo Alto, CA  94301              Foster City, CA  94404

     The foregoing Basic Lease  Information is incorporated into and made a part
     of this Lease.  Defined terms in the Lease shall have the meanings ascribed
     to them in the  Basic  Lease  Information  unless  otherwise  stated.  Each
     reference  in this Lease to any of the Basic Lease  Information  shall mean
     the respective  information above and shall be construed to incorporate all
     of the terms provided under the particular  Lease  paragraph  pertaining to
     such  information.  In the event of any  conflict  between  the Basic Lease
     Information  and the Lease,  the latter shall  control.  The term "days" as
     used in this Lease means "calendar days" unless the specific term "business
     days" is used.


                                       1
<PAGE>


                                TABLE OF CONTENTS
                                                                            Page
     Basic Lease Information...................................................1
     Table of Contents.......................................................2-3
 1.  Premises..................................................................4
 2.  Term......................................................................4
 3.  Possession................................................................4
 4.  Use.....................................................................4-5
 5.  Rules and Regulations.....................................................5
 6.  Rent....................................................................5-6
 7.  Basic Operating Cost....................................................6-7
 8.  Insurance and Indemnification...........................................7-8
 9.  Waiver of Subrogation...................................................8-9
10.  Landlord's Repairs and Services...........................................9
11.  Tenant's Repairs..........................................................9
12.  Alterations............................................................9-10
13.  Signs....................................................................10
14.  Inspection/Posting Notices...............................................10
15.  Utilities................................................................10
16.  Subordination............................................................10
17.  Financial Statements.....................................................10
18.  Estoppel Certificate..................................................10-11
19.  Security Deposit.........................................................11
20.  Tenant's Remedies........................................................11
21.  Assignment and Subletting.............................................11-12
22.  Authority of Parties.....................................................12
23.  Condemnation.............................................................12
24.  Casualty Damage.......................................................12-13
25.  Holding Over.............................................................13
26.  Default...............................................................13-15
27.  Liens....................................................................15
28.  Transfers By Landlord....................................................15
29.  Right of Landlord to Perform Tenant's Covenants..........................15
30.  Waiver...................................................................15
31.  Notices..................................................................15
32.  Attorneys' Fees..........................................................15
33.  Successors and Assigns...................................................16
34.  Force Majeure............................................................16
35.  Brokerage Commission.....................................................16
36.  Miscellaneous.........................................................16-17
37.  Additional Provisions.................................................17-18
38.  Signatures...............................................................19
Exhibits:
 Exhibit A-1...................................................Legal Description
 Exhibit A-2...........................................................Site Plan
 Exhibit A-3...............................................................Phase
Plan
 Exhibit B-1....................................Initial Improvements of Premises
 Exhibit B-2.................................Interior Improvement Specifications
 Exhibit B-3...................................Moveable Equipment/Trade Fixtures
 Exhibit C .......................................Initial Project Specifications



                                       2
<PAGE>


 Exhibit D...........................................Tenant Estoppel Certificate
 Exhibit E.........................Rules and Regulations for Tenants' Contractor



                                       3
<PAGE>


                                      LEASE

   THIS  LEASE is made as of this 8th day of  April,  1998,  by and  between  TC
   Northern  California,  Inc.,  a  Delaware  corporation,  (hereinafter  called
   "Landlord")  and Cellegy  Pharmaceuticals,  Inc.,  a  California  corporation
   (hereinafter called "Tenant").

PREMISES

   1.  Landlord  hereby leases to Tenant,  and Tenant leases from Landlord,  the
       Premises,  for the  Term,  at the  rental,  and upon all of the terms and
       conditions  set forth in this Lease.  The  Premises is  comprised  of the
       Building (sometimes referred to herein as the "Building") and is depicted
       on Exhibit A-2. The Premises  comprises one hundred (100%) percent of the
       rentable area of the Building.  The Building is part of the Project.  The
       Building is outlined in yellow on Exhibit  A-2.  Landlord  shall,  at its
       sole  cost and  expense,  construct  the  Building  shell,  parking  lot,
       exterior  common  areas,  and  landscaping  approximately  in the  manner
       depicted  on Exhibit C hereto  ("Initial  Project  Specifications").  The
       Initial Project  Specifications  shall include,  without limitation,  the
       Building shell,  caulking of interior  concrete joints,  interior stairs,
       roof, all exterior  windows and doors,  fire sprinklers at the roof line,
       and utilities and services to the Building exterior.  Upon the completion
       of the Building shell,  Tenant shall perform Tenant's Work (as defined in
       Exhibit B-1 hereto) for the Premises. Tenant's Work shall be performed in
       the manner described in Exhibit B-1 hereto. 

TERM

   1.  The Term of this Lease ("Term")  shall commence on the Term  commencement
       date and  continue  in full  force and  effect  for the  number of months
       specified as the Length of Term in the Basic Lease  Information  or until
       this  Lease is  terminated  as  otherwise  provided  herein.  If the Term
       commencement  date is a date  other  than the first  day of the  calendar
       month,  the Term  shall be the  number of months of the Length of Term in
       addition  to the  remainder  of the  calendar  month  following  the Term
       commencement date. The Term commencement date ("Term  Commencement Date")
       shall be the later of (a) the Estimated Term  Commencement Date as stated
       in the Basic Lease Information, or (b) the date of Substantial Completion
       of Tenant's Work as provided in Exhibit B-1 hereto.  Within ten (10) days
       after requested by Landlord or Tenant,  Landlord and Tenant shall execute
       an amendment to this Lease stating and confirming  the Term  Commencement
       Date and Tenant's  acceptance of the Premises.  If the shell construction
       is not  substantially  completed  for any reason other than Force Majeure
       (defined  in  Paragraph  34.) or a Default of the  Tenant (as  defined in
       Paragraph  26.  hereto) by December 1, 1998,  Tenant  shall have ten (10)
       days from December 1, 1998 within which to give Landlord  written  notice
       of its intent to  terminate  this Lease.  If such  written  notice is not
       given within the  prescribed  time period,  Tenant's right to cancel this
       Lease shall  terminate,  and the Lease  shall  continue in full force and
       effect.

POSSESSION

   3.  Landlord shall deliver, and Tenant shall accept delivery of, the Premises
       on the Term  Commencement  Date. The Estimated Term  Commencement Date is
       Landlord's  best estimate at the time this Lease is made of the date when
       construction  of  Tenant's  Work  as  provided  in  Exhibit  B-1  will be
       substantially  completed.  If  the  date  of  Substantial  Completion  of
       Tenant's Work is delayed beyond the Estimated Term  Commencement Date due
       to Tenant's  unreasonable  delay in the  construction  of Tenant's  Work,
       Landlord may give a Termination  Notice to Tenant.  Unreasonable delay is
       defined  as a delay of thirty  (30)  days or more by  Tenant to  complete
       tasks  within the  prescribed  time  periods  set forth in  Exhibit  B-1,
       provided  that the thirty  (30) day period may be  extended  up to ninety
       (90) days if Tenant's delay is caused by theft,  fire,  acts of God, acts
       of a public enemy, riot strike,  insurrection,  war, court order,  delays
       caused  by  Landlord,  shortage  of  materials,  requisition  or order of
       governmental  body or  authority.  In the  event  that  Landlord  gives a
       Termination Notice as hereinabove provided,  the Lease shall terminate on
       the third (3rd) day after the Termination Notice is given. Landlord shall
       have no liability to Tenant if the Term  Commencement Date does not occur
       on or within thirty (30) days of the Estimated  Term  Commencement  Date.
       Landlord shall permit Tenant,  or Tenant's agents,  to enter the Premises
       prior to the Term Commencement Date ("Early  Possession") for the purpose
       of  installing   Tenant's  equipment  and  fixtures  provided  that  such
       installation shall not interfere with performance of Landlord's Work. The
       term "Fixture" or "Trade  Fixture" shall be defined as anything  attached
       in any manner to Landlord's property. All portable,  unattached items are
       Tenant's property. Tenant and Landlord agree that Tenant does not own any
       Trade  Fixtures in the Premises  except those items listed in Exhibit B-3
       or otherwise agreed to in a separate writing between Landlord and Tenant.
       Landlord  owns all remaining  Trade  Fixtures.  If Landlord  permits such
       Early  Possession,  from and after the date on which  Tenant or its agent
       first enters the Premises  therefor,  all of the terms and  conditions of
       this Lease  (including,  but not  limited  to,  insurance  and  indemnity
       provisions) shall be applicable to Tenant's occupancy save and except for
       the  requirement  to pay  Base  Rent  and  Basic  Operating  Costs.  Upon
       delivery, Landlord warrants that Landlord's Work, defined in Exhibit B-1,
       will  be  performed  substantially  in  accordance  with  the  plans  and
       specifications  described  herein,  with the exception  that Landlord may
       substitute materials and make other non-material  changes,  provided that
       Landlord's  substitutions and changes will not materially  interfere with
       Tenant's intended use of the Premises as provided herein.
USE

   4.  A.  General.  Tenant shall use the Premises for the Permitted Use and for
       no other use or purpose. Tenant shall control Tenant's employees, agents,
       customers,  visitors,  invitees,  licensees,  contractors,  assignees and
       subtenants  (collectively,  "Tenant's  Parties")  in such a  manner  that
       Tenant and  Tenant's  Parties  cumulatively  do not  exceed  the  Parking
       Density  at  any  time.  Tenant  and  Tenant's  Parties  shall  have  the
       nonexclusive  right to use, in common with other  parties  occupying  the
       Building or the Project,  the parking areas and driveways of the Project,
       and other common areas subject to such rules and  regulations as Landlord
       may from time to time prescribe. Tenant shall have the right, at Tenant's
       option and expense, to designate reserved parking as indicated in Exhibit
       A-2. Landlord shall have no duty to police such reserved parking, and the
       designation  thereof  shall be done in a manner  reasonably  approved  by
       Landlord.

       B.  Limitations.  Tenant shall not permit any odors,  smoke,  dust,  gas,
       substances,  noise or vibrations  to emanate from the Premises,  nor take
       any action which would  constitute a nuisance or would disturb,  obstruct
       or endanger any other tenants of the Building or the Project or interfere
       with their use of their respective premises. Storage outside the Premises
       of  materials,  vehicles  or any  other  items  is  prohibited,  with the
       exception  of  outside  storage  in  areas  designated  and  approved  by
       Landlord.  Tenant may be required to provide  screening  for such outside
       storage, at the discretion of Landlord. Tenant shall not use or allow the
       Premises to be used for any improper,  immoral, unlawful or objectionable
       purpose, nor shall Tenant cause or maintain or permit any nuisance in, on
       or about the Premises or the  Project.  Tenant shall not commit or

                                       4
<PAGE>

       suffer the  commission  of any waste in, on or about the  Premises or the
       Project.  Tenant shall not allow any sale by auction upon the Premises or
       the Project, or place any loads upon the floors,  walls or ceilings which
       endanger  the  structure,  or place any harmful  liquids in the  drainage
       system of the  Building or the  Project.  No waste,  materials  or refuse
       shall be dumped upon or permitted to remain  outside the Premises  except
       in trash containers placed inside exterior enclosures designated for that
       purpose by Landlord.  Landlord shall not be responsible to Tenant for the
       non-compliance  by any other  tenant or occupant  of the  Building or the
       Project  with any of the  above-referenced  rules or any  other  terms or
       provisions  of such  tenant's  or  occupant's  lease or  other  contract.
       Landlord agrees not to unreasonably  enforce any of the  above-referenced
       rules  against  Tenant only and not against other tenants or occupants of
       the Project.

       C. Compliance with Regulations.  By entering the Premises, Tenant accepts
       the  Premises  in the  condition  existing  as of the date of such entry,
       subject to all existing or future applicable municipal, state and federal
       and  other  governmental  statutes,  regulations,  laws  and  ordinances,
       including zoning ordinances and regulations governing and relating to the
       use,  occupancy  and  possession  of the Premises  and the use,  storage,
       generation and disposal of Hazardous Materials  (hereinafter defined) in,
       on and  under  the  Premises  (collectively  "Regulations").  Except  for
       matters which occurred prior to the Term  Commencement  Date and were not
       caused  directly or indirectly  by Tenant or by any of Tenant's  Parties,
       Tenant  shall,  at  Tenant's  sole  expense,  strictly  comply  with  all
       Regulations  now in force or which may hereafter be in force  relating to
       the  Premises  and the  use of the  Premises  and/or  the  use,  storage,
       generation of Hazardous  Materials in, on and under the Premises.  Tenant
       shall at its sole cost and expense obtain any and all licenses or permits
       necessary for Tenant's use of the Premises.  Tenant shall promptly comply
       with the requirements of any board of fire  underwriters or other similar
       body now or hereafter constituted. Tenant shall not do or permit anything
       to be done in, on, or about the Premises or bring or keep anything  which
       will in any way increase the rate of any  insurance  paid for by Landlord
       upon the  Premises,  the  Building or the  Project,  or upon any contents
       therein or cause a  cancellation  of said  insurance or otherwise  affect
       said insurance in any manner. Tenant shall indemnify, defend, protect and
       hold Landlord harmless from and against any loss, cost, expense,  damage,
       attorneys'  fees or  liability  arising  out of the  failure of Tenant to
       comply with any Regulation or comply with the  requirements  as set forth
       herein.

       D. Hazardous Materials.  Tenant shall not cause, or allow any of Tenant's
       Parties to cause, any Hazardous Materials to be used,  generated,  stored
       or  disposed  of on or about the  Premises,  the  Building or the Project
       without  Landlord's  approval,  which approval shall not be  unreasonably
       withheld. As used in this Lease, "Hazardous Materials" shall include, but
       not be limited to, hazardous,  toxic and radioactive  materials and those
       substances  defined as  "hazardous  substances,"  "hazardous  materials,"
       "hazardous wastes," "toxic substances," or other similar  designations in
       any federal,  state,  or local law,  regulation,  or ordinance.  Landlord
       shall have the right at all reasonable  times to inspect the Premises and
       to conduct tests and  investigations  to determine  whether  Tenant is in
       compliance  with  the  foregoing  provisions.   The  costs  of  all  such
       inspections,  tests and investigations  shall be borne by Tenant provided
       that so long as Tenant is not in Default  hereunder  Tenant  shall not be
       responsible  for the cost of more than one (1)  inspection  per  calendar
       year and Tenant's  liability for the cost of each such  inspection  shall
       not exceed  $5,000 per  inspection.  Tenant shall  indemnify,  defend (by
       counsel  selected by Landlord),  protect and hold Landlord  harmless from
       and against all liabilities,  losses, costs and expenses, demands, causes
       of action,  claims or judgments directly or indirectly arising out of the
       use, generation,  storage or disposal of Hazardous Materials by Tenant or
       any  of  Tenant's  Parties,   which  indemnity  shall  include,   without
       limitation, attorneys' and consultants' fees, the cost of any required or
       necessary repair,  cleanup or detoxification,  and the preparation of any
       closure or other  required  plans,  whether  such  action is  required or
       necessary  prior to or following the  termination of this Lease.  Neither
       the  written  consent  by  Landlord  to the use,  generation,  storage or
       disposal of Hazardous  Materials nor the strict compliance by Tenant with
       all laws  pertaining  to Hazardous  Materials  shall  excuse  Tenant from
       Tenant's  obligation of  indemnification  pursuant to this Paragraph 4.D.
       Tenant's  obligations  pursuant to the foregoing  indemnity shall survive
       the termination of this Lease.

RULES AND
REGULATIONS

   5.  Tenant shall faithfully observe and comply with any rules and regulations
       Landlord  may from time to time  prescribe  in writing for the purpose of
       maintaining  the  proper  care,  cleanliness,  safety,  traffic  flow and
       general order of the Premises, the Building, or the Project. Tenant shall
       cause  Tenant's  Parties to comply  with all such rules and  regulations.
       Landlord shall not be responsible to Tenant for the non-compliance by any
       other  tenant or occupant of the  Building or the Project with any of the
       rules and regulations.

RENT

   6.  A. Base Rent. Base Rent for the Premises shall be calculated on the basis
       of the rentable square feet of the Premises at the rates specified in the
       Basic Lease  Information.  Rentable  square feet shall  include all areas
       inside the  Building as  determined  by  Landlord's  architect.  Tenant's
       obligation to pay Base Rent for the Premises  shall  commence on the Term
       Commencement  Date.  Upon  completion  of  Landlord's  Work,   Landlord's
       architect  shall  certify to  Landlord  the  rentable  square feet of the
       Premises,  measured  from the outside of exterior  walls,  but  including
       areas  below  the  "dripline"  in the  exterior  entrances  and exits and
       including  areas in the  Building  such as, but not limited  to,  utility
       rooms and shafts for mechanical equipment.  Landlord and Tenant currently
       estimate that the rentable  square feet of the Premises and the Base Rent
       for the Premises will be as stated in the Basic Lease  Information.  Upon
       receipt of the  architect's  certification  of rentable  square feet, the
       actual Base Rent shall be  determined  and, if  requested  by Landlord or
       Tenant,  Landlord  and Tenant shall enter into an amendment of this Lease
       which states the actual Base Rent as so determined. Upon determination of
       the actual Base Rent for the Premises,  Landlord and Tenant shall adjust,
       if necessary,  the Base Rent deposited by Tenant for the first full month
       of the Term as provided in Paragraph  6.B.  below,  and Tenant's share of
       Operating Costs, as defined in Paragraph 7A. theretofore paid.

       B. Payments. Tenant shall pay to Landlord,  without demand throughout the
       Term,  Base Rent as specified in the Basic Lease  Information and finally
       determined as provided in Paragraph 6.A., payable in monthly installments
       in advance on or before the first day of each calendar  month,  in lawful
       money of the United States,  without deduction or offset  whatsoever,  at
       the address  specified  in the Basic Lease  Information  or to such other
       place as Landlord may from time to time  designate in writing.  Base Rent
       and Estimated  Basic Operating Costs as defined in Paragraph 7.A. for the
       first full month of the Term (based upon the  estimated  rentable area as
       hereinabove  provided) shall be paid by Tenant upon Tenant's execution of
       this Lease. If the obligation for payment of Base Rent commences on other
       than the first day of a month,  then  Base Rent  (calculated  at the rate
       applicable  to the second full month of the Term) for the  partial  month
       shall be prorated on the basis of the actual number of days in the month.

                                       5
<PAGE>

       C.  Additional  Rent. All monies other than Base Rent required to be paid
       by Tenant hereunder, including, but not limited to, the interest and late
       charge  described  in  Paragraph  26.D.,  any  monies  spent by  Landlord
       pursuant to  Paragraph  29., and  Tenant's  Proportionate  Share of Basic
       Operating  Costs,  as specified  in Paragraph 7. of this Lease,  shall be
       considered  additional rent ("Additional  Rent").  "Rent" shall mean Base
       Rent and Additional Rent.

    BASIC
OPERATING
     COST

   7.  A. Basic Operating Cost. In addition to the Base Rent required to be paid
       hereunder,  Tenant shall pay as Additional Rent, Basic Operating Costs in
       the manner set forth below. The Basic Operating Costs shall be calculated
       on the basis of  Landlord's  architect's  certification  of the  rentable
       square  feet  of the  Building  and the  Project.  The  certification  by
       Landlord's  architect of the rentable square feet of the Building and the
       Project shall be conclusive and binding upon both Landlord and Tenant for
       all purposes of this Lease.  Tenant's  obligation to pay Basic  Operating
       Costs with respect to the Building and the Project shall  commence on the
       Term  Commencement  Date.  Landlord  shall account for each item of Basic
       Operating  Costs  attributable  to  the  Building  and  the  Project,  as
       determined by Landlord in Landlord's sole discretion, and unless provided
       to the  contrary  in this  Lease,  Tenant  shall pay the Basic  Operating
       Costs,  as set forth in the Basic  Lease  Information.  "Basic  Operating
       Costs"  shall mean all  expenses and costs of every kind and nature which
       Landlord shall pay or become obligated to pay because of or in connection
       with the  management,  maintenance,  preservation  and  operation  of the
       Building  and  the  Project  (determined  in  accordance  with  generally
       accepted accounting  principles,  consistently applied) including but not
       limited to the following:

       (1) Taxes. All real property taxes,  possessory interest taxes,  business
       or license taxes or fees, service payments in lieu of such taxes or fees,
       annual or periodic license or use fees, excises, transit charges, housing
       fund  assessments,  open  space  charges,  assessments,  levies,  fees or
       charges general and special,  ordinary and  extraordinary,  unforeseen as
       well as foreseen,  of any kind  (including fees "in-lieu" of any such tax
       or assessment) which are assessed, levied, charged, confirmed, or imposed
       by any public authority upon the Project,  its operations or the Rent (or
       any portion or component thereof) (all of the foregoing being hereinafter
       collectively referred to as "real property taxes"), or any tax imposed in
       substitution, partially or totally, of any tax previously included within
       the definition of real property  taxes,  or any additional tax the nature
       of which was previously  included  within the definition of real property
       taxes,  except (a)  inheritance  or estate taxes imposed upon or assessed
       against the  Project,  or any part thereof or interest  therein,  and (b)
       taxes  computed  upon the basis of net income of Landlord or the owner of
       any  interest  therein,  except as  otherwise  provided in the  following
       sentence.   Basic   Operating   Costs  shall  also   include  any  taxes,
       assessments,  or any other fees imposed by any public  authority  upon or
       measured  by the  monthly  rental  or other  charges  payable  hereunder,
       including,  without limitation, any gross income tax or excise tax levied
       by the local governmental  authority in which the Project is located, the
       federal  government,  or any  other  governmental  body with  respect  to
       receipt  of such  rental,  or upon,  with  respect to or by reason of the
       development,  possession,  leasing, operation,  management,  maintenance,
       alteration,  repair,  use or  occupancy  by Tenant of the Premises or any
       portion thereof, or upon this transaction or any document to which Tenant
       is a party  creating  or  transferring  an  interest  or an estate in the
       Premises.  In the  event  that it  shall  not be  lawful  for  Tenant  to
       reimburse  Landlord  for all or any part of such  taxes,  the  Base  Rent
       payable to Landlord  under this Lease shall be revised to net to Landlord
       the same net rental  after  imposition  of any such taxes on  Landlord as
       would have been  payable  to  Landlord  prior to the  payment of any such
       taxes.  If  Landlord  at any time during the Term of this Lease or within
       two (2) years after  termination  of this Lease shall receive a refund of
       real property taxes  applicable to a period within the Term of this Lease
       for which Tenant has paid real property taxes  hereunder,  Landlord shall
       refund to Tenant Tenant's proportionate share of said refund if Tenant is
       not then in  Default  or was not in  Default  at the  termination  of the
       Lease,  as the case may be. If Tenant timely pays real property  taxes to
       Landlord,  Landlord alone shall be responsible for any fines,  penalties,
       interest and other  charges that result from any late payment of taxes by
       Landlord.

       (2)  Insurance.  All  insurance  premiums  and costs,  including  but not
       limited  to, any  deductible  amounts,  premiums  and costs of  insurance
       incurred by Landlord, as more fully set forth in Paragraph 8.A. herein.

       (3) Repairs and Improvements.  The cost of all repairs,  replacements and
       general  maintenance  for the  Premises,  the  Building  and the  Project
       (except for those repairs expressly made the financial  responsibility of
       Landlord pursuant to the terms of this Lease,  repairs to the extent paid
       for by proceeds of  insurance  or by Tenant or other third  parties,  and
       alterations  attributable  solely to  tenants of the  Project  other than
       Tenant).  Tenant  shall not be  responsible  for the cost of  repairs  to
       tenant-occupied  buildings  which are part of the Project  other than the
       Building.  Such  repairs,  replacements,  and general  maintenance  shall
       include the cost of any capital  improvements  made to or capital  assets
       acquired for the Project,  the Building,  or the Premises  after the Term
       Commencement Date that are intended by Landlord to reduce any other Basic
       Operating Cost, are reasonably necessary for the health and safety of the
       occupants of the Project,  or are made to the Building by Landlord  after
       the date of this Lease and are  required  under any  governmental  law or
       regulation, such costs or allocable portions thereof to be amortized over
       the  useful  life of the  improvement,  as  determined  by the  Landlord,
       together  with  interest on the  unamortized  balance at the "prime rate"
       charged at the time such  improvements  or capital assets are constructed
       or  acquired  by Wells  Fargo Bank,  N.A.  (San  Francisco)  plus two (2)
       percentage  points,  but in no event more than the maximum rate permitted
       by law.

       (4)  Services.  To the extent such  expenses  are not the  obligation  of
       Tenant under other  provisions  of this Lease,  all expenses  relating to
       maintenance, janitorial and service agreements and services, and costs of
       supplies and equipment  used in operating and  maintaining  the Premises,
       the Building and the Project and the  equipment  therein and the adjacent
       sidewalks,  driveways,  parking and  service  areas,  including,  without
       limitation,  alarm service,  window cleaning,  elevator maintenance,  the
       Building exterior maintenance and Project landscaping.

       (5)  Utilities.  To the extent such  expenses are not the  obligation  of
       Tenant under other  provisions  of this Lease,  the cost of all utilities
       which  benefit  all or a portion of the  Premises,  the  Building  or the
       Project.

       (6) Management  Fee. A management and accounting  cost recovery fee equal
       to three (3%) percent of the sum of Base Rent and Basic Operating Cost.

       (7) Legal and Accounting.  Legal and accounting  expenses relating to the
       Project  other than legal  expenses  related to  negotiating  leases with
       tenants  in  the  Project.   Accounting  expenses  shall  be  limited  to
       preparation of annual  reconciliation  of estimated and actual  Operating
       Costs.

                                       6
<PAGE>

       In the event that the  Building is not fully  occupied  during any fiscal
       year of the Term as determined by Landlord,  an adjustment  shall be made
       in computing the Basic  Operating Costs for such year so that Tenant pays
       an equitable  portion of all variable items of Basic Operating  Costs, as
       reasonably  determined by Landlord;  provided,  however, that in no event
       shall  Landlord be  entitled  to collect in excess of one hundred  (100%)
       percent of the total Basic Operating Costs from all of the tenants in the
       Building including Tenant.

       Basic Operating  Costs shall not include  specific costs incurred for the
       account  of,   separately   billed  to  and  paid  by  specific  tenants.
       Notwithstanding  anything herein to the contrary, in any instance wherein
       Landlord,  in Landlord's sole discretion,  deems Tenant to be responsible
       for any amounts greater than Tenant's Proportionate Share, Landlord shall
       have the right to allocate costs in any manner Landlord  reasonably deems
       appropriate.

       B. Payment of Estimated Basic Operating Cost.  "Estimated Basic Operating
       Costs" for any  particular  year shall mean  Landlord's  estimate  of the
       Basic  Operating Cost for such fiscal year made prior to  commencement of
       such fiscal year as hereinafter  provided.  Landlord shall have the right
       from  time to time to  revise  its  fiscal  year and  interim  accounting
       periods so long as the  periods as so revised are  reconciled  with prior
       periods in  accordance  with  generally  accepted  accounting  principles
       applied in a consistent manner. During the last month of each fiscal year
       during the Term, or as soon  thereafter as  practicable,  Landlord  shall
       give Tenant written notice of the Estimated Basic Operating Costs for the
       ensuing fiscal year. Tenant shall pay Tenant's Proportionate Share of the
       Estimated  Basic  Operating Cost with  installments  of Base Rent for the
       fiscal  year to which the  Estimated  Basic  Operating  Cost  applies  in
       monthly  installments on the first day of each calendar month during such
       year,  in advance.  If at any time during the course of the fiscal  year,
       Landlord  determines  that Basic Operating Cost is projected to vary from
       the then Estimated  Basic  Operating Cost by more than ten (10%) percent,
       Landlord may, by written  notice to Tenant,  revise the  Estimated  Basic
       Operating Cost for the balance of such fiscal year, and Tenant's  monthly
       installments  for the remainder of such year shall be adjusted so that by
       the end of  such  fiscal  year  Tenant  has  paid  to  Landlord  Tenant's
       Proportionate  Share of the revised  Estimated  Basic  Operating Cost for
       such year. Upon execution of this Lease, Tenant shall pay to Landlord the
       Estimated  Basic  Operating  Cost  for the  Premises  (calculated  on the
       estimated  rentable  square  feet) for the first  full month of the Term.
       Upon final determination of the rentable square feet, Landlord and Tenant
       shall adjust such estimated payment.

       C. Computation of Basic Operating Cost Adjustment.  "Basic Operating Cost
       Adjustment"  shall mean the difference  between Estimated Basic Operating
       Cost  and  Basic  Operating  Cost  for  any  fiscal  year  determined  as
       hereinafter provided.  Within one hundred twenty (120) days after the end
       of each fiscal year, as determined by Landlord,  or as soon thereafter as
       practicable,  Landlord  shall  deliver  to  Tenant a  statement  of Basic
       Operating  Cost  for  the  fiscal  year  just  ended,  accompanied  by  a
       computation of Basic Operating Cost  Adjustment.  If such statement shows
       that Tenant's  payment based upon Estimated  Basic Operating Cost is less
       than Tenant's  Proportionate  Share of Basic  Operating Cost, then Tenant
       shall pay to  Landlord  the  difference  within  twenty  (20) days  after
       receipt of such statement. If such statement shows that Tenant's payments
       of Estimated Basic Operating Cost exceed Tenant's  Proportionate Share of
       Basic  Operating Cost, then (provided that Tenant is not in Default under
       this Lease)  Landlord shall credit the  difference  against the Estimated
       Basic  Operating Cost payment next due. If this Lease has been terminated
       or the Term hereof has expired prior to the date of such statement,  then
       the Basic  Operating  Cost  Adjustment  shall be paid by the  appropriate
       party within twenty (20) days after the date of delivery of the statement
       and this obligation shall survive  termination of the Lease.  Should this
       Lease  commence or  terminate at any time other than the first day of the
       fiscal year,  Tenant's  Proportionate  Share of the Basic  Operating Cost
       adjustment shall be prorated by reference to the exact number of calendar
       days during such fiscal year that this Lease is in effect.

       D. Net  Lease.  This  shall be a net Lease and Base Rent shall be paid to
       Landlord absolutely net of all costs and expenses, except as specifically
       provided to the  contrary in this Lease.  The  provisions  for payment of
       Basic Operating Cost and the Basic Operating Cost Adjustment are intended
       to pass on to Tenant and reimburse Landlord for all costs and expenses of
       the nature  described in Paragraph 7.A.  incurred in connection  with the
       management,  maintenance,  preservation  and operation of the Building or
       the Project and such additional facilities now and in subsequent years as
       may be  determined  by Landlord to be  necessary  to the  Building or the
       Project.

       E. Tenant  Audit.  In the event that Tenant shall  dispute the amount set
       forth in any statement  provided by Landlord under Paragraph 7.B. or 7.C.
       above,  Tenant  shall  have the  right,  not later  than  sixty (60) days
       following  the  receipt of such  statement  and upon the  condition  that
       Tenant  shall  first  deposit  with  Landlord  the full amount in dispute
       within sixty (60) days of receipt of such statement,  to cause Landlord's
       books and records  with respect to Basic  Operating  Cost for such fiscal
       year to be audited by certified public accountants selected by Tenant and
       subject to Landlord's  reasonable right of approval.  The Basic Operating
       Cost  Adjustment  shall be  appropriately  adjusted  on the basis of such
       audit. If such audit discloses a liability for a refund in excess of five
       (5%) percent of Tenant's  Proportionate Share of the Basic Operating Cost
       Adjustment previously reported,  the cost of such audit shall be borne by
       Landlord;  otherwise  the cost of such audit shall be paid by Tenant.  If
       Tenant shall not request an audit in  accordance  with the  provisions of
       this  Paragraph  7.E.  within sixty (60) days after receipt of Landlord's
       statement  provided  pursuant to Paragraph  7.B. or 7.C.,  such statement
       shall be final and binding for all purposes hereof.

 INSURANCE
       AND
    INDEM-
NIFICATION

   8.  A. Landlord's  Insurance.  Landlord agrees to maintain insurance insuring
       the Building against fire,  lightning,  vandalism and malicious  mischief
       (including, if Landlord elects, "All Risk" coverage,  earthquake,  and/or
       flood  insurance),  in an  amount  of not less  than one  hundred  (100%)
       percent  of  the  current   replacement   cost   thereof,   except  where
       commercially unreasonable, with deductibles and the form and endorsements
       of such  coverage  as  selected  by  Landlord.  Such  insurance  may also
       include,  at Landlord's  option,  insurance against loss of Base Rent and
       Additional  Rent,  in an  amount  equal to the  amount  of Base  Rent and
       Additional  Rent  payable by Tenant for a period of at least  twelve (12)
       months  commencing on the date of loss.  Such insurance  shall be for the
       sole  benefit of Landlord and under  Landlord's  sole  control.  Landlord
       shall not be obligated  to insure any  furniture,  equipment,  machinery,
       goods or supplies  which Tenant may keep or maintain in the Premises,  or
       any leasehold improvements, additions or alterations within the Premises.
       Landlord may also carry such other insurance as Landlord may deem prudent
       or advisable, including, without limitation,  liability insurance in such
       amounts and on such terms as Landlord shall determine.

                                       7
<PAGE>

       B.  Tenant's Insurance.

       (1) Property  Insurance.  Tenant shall  procure at Tenant's sole cost and
       expense  and keep in effect  from the date of this Lease and at all times
       until  the  end of the  Term,  insurance  on all  personal  property  and
       Fixtures  of Tenant  and all  improvements  made by or for  Tenant to the
       Premises,  insuring such property for the full replacement  value of such
       property.

       (2) Liability  Insurance.  Tenant shall procure at Tenant's sole cost and
       expense  and keep in effect  from the date of this Lease and at all times
       until  the  end  of  the  Term  either  Comprehensive  General  Liability
       insurance or Commercial  General Liability  insurance applying to the use
       and occupancy of the Premises and the  Building,  and any part of either,
       and any areas adjacent  thereto,  and the business operated by Tenant, or
       by any other occupant on the Premises. Such insurance shall include Broad
       Form Contractual  Liability  insurance  coverage insuring all of Tenant's
       indemnity  obligations  under  this  Lease.  Such  coverage  shall have a
       minimum  combined  single  limit of  liability  of at least  two  million
       dollars  ($2,000,000.00),  and a general  aggregate limit of five million
       dollars  ($5,000,000.00).  All such policies shall be written to apply to
       all bodily injury,  property  damage or loss,  personal  injury and other
       covered loss, however occasioned, occurring during the policy term, shall
       be  endorsed   to  add   Landlord,   Riggs  Bank  N.A.,   as  trustee  of
       Multi-Employer  Trust, the Multi-Employer  Trust, Kennedy Associates Real
       Estate Counsel,  Inc., and the officers,  agents and employees of each of
       the foregoing  entities,  and any party holding an interest to which this
       Lease may be  subordinated  as an additional  insured,  and shall provide
       that such coverage shall be primary and that any insurance  maintained by
       Landlord shall be excess insurance only. Such coverage shall also contain
       endorsements:  (i)  deleting any  employee  exclusion on personal  injury
       coverage; (ii) including employees as additional insureds; (iii) deleting
       any liquor  liability  exclusion;  and (iv)  providing  for  coverage  of
       employer's automobile  non-ownership  liability. All such insurance shall
       provide for  severability  of  interests;  shall  provide  that an act or
       omission of one of the named  insureds shall not reduce or avoid coverage
       to the other named  insureds;  and shall  afford  coverage for all claims
       based on acts,  omissions,  injury and damage,  which claims  occurred or
       arose  (or the  onset of which  occurred  or  arose)  in whole or in part
       during  the  policy  period.   Said  coverage  shall  be  written  on  an
       "occurrence"  basis, if available.  If an "occurrence"  basis form is not
       available,  Tenant must purchase  "tail"  coverage for the most number of
       years  available,  and tenant must also purchase  "tail"  coverage if the
       retroactive date of an "occurrence"  basis form is changed so as to leave
       a gap in  coverage  for  occurrences  that might have  occurred  in prior
       years.  If a  "claims  made"  policy is ever  used,  the  policy  must be
       endorsed so that Landlord is given the right to purchase  "tail" coverage
       should Tenant for any reason not do so or if the policy is to be canceled
       for nonpayment of premium.

       (3) General  Insurance  Requirements.  All  coverages  described  in this
       Paragraph  8.B.  shall be endorsed to provide  Landlord  with thirty (30)
       days' notice of  cancellation  or change in terms.  If at any time during
       the Term the amount or coverage of insurance  which Tenant is required to
       carry under this  Paragraph 8.B. is, in Landlord's  reasonable  judgment,
       materially less than the amount or type of insurance  coverage  typically
       carried by owners or tenants of properties located in the general area in
       which the  Premises  are located  which are similar to and  operated  for
       similar  purposes  as the  Premises,  Landlord  shall  have the  right to
       require  Tenant to increase  the amount or change the types of  insurance
       coverage  required  under this  Paragraph  8.B.  All  insurance  policies
       required  to be carried  under this Lease  shall be written by  companies
       rated A or  better in  "Best's  Insurance  Guide"  and  authorized  to do
       business  in  California.  Any  deductible  amounts  under any  insurance
       policies required  hereunder shall be subject to Landlord's prior written
       approval.  In any event deductible  amounts shall not exceed one thousand
       dollars  ($1,000.00).  Tenant shall  deliver to Landlord on or before the
       Term  Commencement  Date, and thereafter at least thirty (30) days before
       the  expiration  dates of the  expiring  policies,  certified  copies  of
       Tenant's insurance policies, or a certificate  evidencing the same issued
       by the insurer  thereunder,  showing that all premiums have been paid for
       the full policy  period;  and, in the event  Tenant shall fail to procure
       such  insurance,  or to deliver such policies or  certificates,  Landlord
       may, at Landlord's option and in addition to Landlord's other remedies in
       the event of a  Default  by Tenant  hereunder,  procure  the same for the
       account of Tenant,  and the cost  thereof  shall be paid to  Landlord  as
       Additional Rent.

       C.  Indemnification.  Landlord shall not be liable to Tenant for any loss
       or damage to person or property caused by theft,  fire, acts of God, acts
       of  a  public  enemy,  riot,  strike,  insurrection,  war,  court  order,
       requisition or order of governmental  body or authority or for any damage
       or inconvenience which may arise through repair or alteration of any part
       of the Building or the Project or failure to make any such repair, except
       as expressly  otherwise provided in Paragraph 10. Tenant shall indemnify,
       defend by counsel  acceptable  to  Landlord,  protect  and hold  Landlord
       harmless  from  and  against  any and  all  liabilities,  losses,  costs,
       damages,  injuries or expenses,  including reasonable attorneys' fees and
       court  costs,  arising  out of or related  to: (1) claims of injury to or
       death of persons or damage to property occurring or resulting directly or
       indirectly from the use or occupancy of the Premises,  or from activities
       of  Tenant,  Tenant's  Parties  or  anyone in or about  the  Premises  or
       Project,  or from any  cause  whatsoever;  (2)  claims  for work or labor
       performed, or for materials or supplies furnished to or at the request of
       Tenant in connection with performance of any work done for the account of
       Tenant  within the Premises or Project;  and (3) claims  arising from any
       breach  or  Default  on the  part of  Tenant  in the  performance  of any
       covenant  contained in this Lease.  The foregoing  indemnity shall not be
       applicable  to  claims  arising  from the  gross  negligence  or  willful
       misconduct of Landlord and Landlord shall  indemnify  Tenant for any loss
       incurred by Tenant as a direct  consequence of any such gross  negligence
       or willful misconduct of Landlord. The provisions of this Paragraph shall
       survive the  expiration or  termination of this Lease with respect to any
       claims or liability occurring prior to such expiration or termination.

  WAIVER OF
SUBROGATION

   9.  To the  extent  permitted  by law  and  without  affecting  the  coverage
       provided by insurance  to be  maintained  hereunder,  Landlord and Tenant
       each waive any right to recover  against  the other for:  (a) damages for
       injury to or death of persons;  (b) damages to  property;  (c) damages to
       the Premises or any part thereof, and (d) claims arising by reason of the
       foregoing  due to hazards  covered by insurance to the extent of proceeds
       recovered  therefrom.  This provision is intended to waive fully, and for
       the benefit of each party, any rights and/or claims which might give rise
       to a right of subrogation in favor of any insurance carrier. The coverage
       obtained  by each party  pursuant to this Lease  shall  include,  without
       limitation,  a waiver of subrogation by the carrier which conforms to the
       provisions of this Paragraph.

 LANDLORD'S
REPAIRS AND
   SERVICES

   10. Except  for  damage,  destruction  or  deterioration  which is  caused by
       Tenant,  Tenant's  Parties,  or by an act or  event  which  is not  fully
       insured,  Landlord  shall at Landlord's  expense  maintain the structural
       soundness  of

                                       8
<PAGE>

       the structural  beams of the roof, the  foundations and exterior walls of
       the Building in good repair, reasonable wear and tear excepted;  provided
       that,  Landlord  shall  not be  responsible  for the cost of any  repairs
       resulting from damage,  destruction or  deterioration  which is caused by
       Tenant,  Tenant's  Parties,  or by an act or  event  which  is not  fully
       insured.  The term  "exterior  walls" as used  herein  shall not  include
       windows,  glass or plate  glass,  doors,  special  store fronts or office
       entries.  Landlord shall perform on behalf of Tenant and other tenants of
       the Project, as an item of Basic Operating Cost, the exterior maintenance
       of the Building, the Project, and public and common areas of the Project,
       including but not limited to the roof, pest extermination, the landscaped
       areas, parking areas, driveways,  the truck staging areas, fire sprinkler
       systems,  sanitary and storm sewer lines, utility services,  electric and
       telephone  equipment  servicing the Building(s),  exterior lighting,  and
       anything  which  affects the  operation  and exterior  appearance  of the
       Project,  which  determination  shall be at Landlord's  sole  discretion.
       Except  for  the  expenses  directly  involving  the  items  specifically
       described  in the first  sentence of this  Paragraph  10.,  Tenant  shall
       reimburse Landlord for all such costs in accordance with Paragraph 7. Any
       damage caused by or repairs necessitated by any act of Tenant or Tenant's
       Parties may be repaired by Landlord at Landlord's  option and at Tenant's
       expense.  Tenant shall  immediately  give Landlord  written notice of any
       defect or need of repairs  after which  Landlord  shall have a reasonable
       opportunity  to repair  same.  Landlord's  liability  with respect to any
       defects,  repairs, or maintenance for which Landlord is responsible under
       any of the  provisions of this Lease shall be limited to the cost of such
       repairs or  maintenance.  Landlord shall provide  Tenant with  reasonable
       notice before entering the Premises to conduct repairs.

TENANT'S
 REPAIRS

   11. Tenant  shall at  Tenant's  expense  throughout  the  Term of this  Lease
       maintain all parts of the Premises in a good,  clean and secure condition
       and promptly make all necessary repairs and  replacements,  including but
       not limited to all windows, glass, doors, walls and wall finishes,  floor
       covering, heating, ventilating and air conditioning systems, truck doors,
       dock bumpers, dock plates and levelers,  plumbing work and Fixtures, root
       (exclusive  of structural  beams),  downspouts,  electrical  and lighting
       systems,  and fire  sprinklers.  Tenant  shall at Tenant's  expense  also
       perform regular removal of trash and debris.  If required by the railroad
       company,  Tenant agrees to sign a joint maintenance  agreement  governing
       the use of the rail spur, if any.  Tenant shall, at Tenant's own expense,
       enter into a regularly scheduled preventive  maintenance/service contract
       with a maintenance  contractor  for servicing all hot water,  heating and
       air  conditioning  systems and equipment  within or serving the Premises.
       The maintenance contractor and the contract must be approved by Landlord.
       The service contract must include all services suggested by the equipment
       manufacturer  within the  operation/maintenance  manual  and must  become
       effective  and a copy thereof  delivered to Landlord  within  thirty (30)
       days  after the Term  Commencement  Date.  Tenant  shall not  damage  any
       demising  wall or disturb  the  integrity  and  support  provided  by any
       demising  wall and shall,  at its sole  expense,  immediately  repair any
       damage to any demising wall caused by Tenant or Tenant's Parties.  To the
       extent  permitted by  applicable  contracts or law,  Landlord  shall make
       available to Tenant the benefits of any contractor  warranties applicable
       to  items  for  which  Tenant  has  repair,  maintenance  or  replacement
       responsibility hereunder,  provided,  however, that Landlord shall not be
       obligated to incur any cost or liability in so doing.

ALTERATIONS

   12. Tenant shall not make, or allow to be made,  any  Alterations or physical
       additions  in,  about or to the  Premises  without  obtaining  the  prior
       written consent of Landlord,  except as stated below, which consent shall
       not be  unreasonably  withheld with respect to proposed  alterations  and
       additions which: (a) comply with all applicable laws,  ordinances,  rules
       and  regulations;  (b) are in  Landlord's  opinion,  compatible  with the
       Project and its mechanical, plumbing, electrical, heating/ventilation/air
       conditioning  systems,  (c) are constructed  utilizing Union Labor as set
       forth in Section 2.5. of Exhibit B-1; (d) will not interfere with the use
       and  occupancy of any other portion of the Building or the Project by any
       other tenant or its invitees; (e) are performed promptly and in a workman
       like  manner;  (f) the  Project  remains  lien  free as a  result  of the
       construction;  and (g) are constructed using all new materials.  The term
       "Alteration"  as  used  herein  is  defined  as  alterations,  additions,
       substitutions,  installations,  changes and  improvements,  but  excludes
       minor  decorations.  Tenant  shall  have  the  right  to make up to fifty
       thousand dollars ($50,000) worth of Alterations to the Premises per year,
       which would  otherwise  be  permissible  under the Lease and which do not
       involve  demolition  or effect the  structural  parts or  exterior of the
       Building, without obtaining the prior written consent of Landlord. In the
       event Landlord's prior written consent is not necessary  pursuant to this
       section, Tenant shall nevertheless submit to Landlord copies of its plans
       and  specification,  and Tenant's work shall be performed pursuant to the
       other  requirements of this section.  Specifically,  but without limiting
       the generality of the foregoing, Landlord shall have the right of written
       consent for all plans and specifications for the proposed  Alterations or
       additions,  construction means and methods,  all appropriate  permits and
       licenses,  any contractor or  subcontractor to be employed on the work of
       Alteration  or  additions,  and the time for  performance  of such  work.
       Tenant  shall also  supply to  Landlord  any  documents  and  information
       reasonably   requested  by  Landlord  in   connection   with   Landlord's
       consideration of a request for approval hereunder. Tenant shall reimburse
       Landlord  for all  costs  which  Landlord  may incur in  connection  with
       granting  approval  to Tenant  for any such  Alterations  and  additions,
       including any costs or expenses  which  Landlord may incur in electing to
       have   outside   architects   and   engineers   review   said  plans  and
       specifications.  All such Alterations, physical additions or improvements
       shall remain the property of Tenant until  termination of this Lease,  at
       which time they shall be and become the  property of Landlord if Landlord
       so elects;  provided,  however,  that Landlord may, at Landlord's option,
       require that Tenant, at Tenant's expense,  remove any or all Alterations,
       additions,  improvements  and  partitions  made by Tenant and restore the
       Premises by the  termination of this Lease,  whether by lapse of time, or
       otherwise,  to their condition  existing prior to the construction of any
       such alterations, additions, partitions or leasehold improvements, except
       for initial  Tenant  Improvements  made pursuant to Exhibit B-1. All such
       removals and restoration  shall be accomplished in a good and workmanlike
       manner  so as  not  to  cause  any  damage  to the  Premises  or  Project
       whatsoever.  If Tenant  fails to so remove such  alterations,  additions,
       improvements  and  partitions  or Tenant's  Trade  Fixtures or furniture,
       Landlord may keep and use them or remove any of them and cause them to be
       stored or sold in  accordance  with  applicable  law,  at  Tenant's  sole
       expense.  In addition to and wholly apart from Tenant's obligation to pay
       Tenant's  Proportionate  Share of Basic Operating  Cost,  Tenant shall be
       responsible  for  and  shall  pay  prior  to  delinquency  any  taxes  or
       governmental service fees,  possessory interest taxes, fees or charges in
       lieu of any such taxes,  capital  levies,  or other charges imposed upon,
       levied with respect to or assessed against its personal property,  on the
       value of the alterations,  additions or improvements within the Premises,
       and on Tenant's  interest  pursuant to this Lease. To the extent that any
       such taxes are not separately assessed or billed to Tenant,  Tenant shall
       pay the amount thereof as invoiced to Tenant by Landlord.

SIGNS

   13. Subject to the provisions of this Section,  Tenant may, at Tenant's cost,
       erect  a  sign  on  the  Premises.  All  signs,  notices,   graphics  and
       advertising  balloons  of every  kind or  character,  visible  in or from
       public  view or  corridors,  the  common  areas  or the  exterior  of the
       Premises, shall be subject to Landlord's prior written approval. Landlord
       shall  provide,  at  Landlord's  cost,  monument  signage on Oyster Point
       Boulevard which identifies  Tenant's business.  Tenant shall not place or
       maintain any banners whatsoever or any window decor in or on any exterior
       window or window  fronting  upon any common areas or service area or upon
       any truck doors or man doors without  Landlord's prior written

                                       9
<PAGE>

       approval.  Any installation of signs or graphics on or about the Premises
       and Project shall be subject to any applicable  governmental laws, CC&Rs,
       ordinances,   regulations  and  to  any  other  requirements  imposed  by
       Landlord.  Tenant shall  remove all such signs and graphics  prior to the
       termination of this Lease. Such  installations and removals shall be made
       in such manner as to avoid  injury or  defacement  of the  Premises,  the
       Building or the Project and any other improvements contained therein, and
       Tenant  shall  repair  any  injury  or  defacement,   including   without
       limitation, discoloration caused by such installation or removal.

INSPECTION/
    POSTING
    NOTICES

   14.After reasonable notice,  except in emergencies where no such notice shall
       be required,  Landlord, and Landlord's agents and representatives,  shall
       have the right to enter the  Premises to inspect the same,  to clean,  to
       perform  such work as may be  permitted  or required  hereunder,  to make
       repairs or  alterations  to the  Premises  or Project or to other  tenant
       spaces therein, to deal with emergencies,  to post such notices as may be
       permitted or required by law to prevent the  perfection  of liens against
       Landlord's  interest  in  the  Project  or to  exhibit  the  Premises  to
       prospective tenants, purchasers, encumbrances or others, or for any other
       purpose as Landlord may deem necessary or desirable;  provided,  however,
       that Landlord shall use reasonable efforts not to unreasonably  interfere
       with Tenant's business operations. Provided that Tenant is not in Default
       hereunder,   Landlord  shall  not  advertise  or  show  the  Premises  to
       prospective  successor  tenants except during the last twelve (12) months
       of the Lease term.  Tenant shall not be entitled to any abatement of Rent
       by reason of the exercise of any such right of entry.  At any time within
       six (6)  months  prior to the end of the Term,  Landlord  shall  have the
       right to erect on the Premises  and/or Project a suitable sign indicating
       that the Premises are available for lease,  but agrees not to attach such
       sign  directly  to the  Building.  Tenant  shall give  written  notice to
       Landlord at least  thirty (30) days prior to vacating  the  Premises  and
       shall meet with  Landlord for a joint  inspection  of the Premises at the
       time of vacating. In the event of Tenant's failure to give such notice or
       participate in such joint inspection,  Landlord's  inspection at or after
       Tenant's  vacating the Premises shall  conclusively be deemed correct for
       purposes  of  determining   Tenant's   responsibility   for  repairs  and
       restoration.

UTILITIES

   15. Tenant shall pay directly for all water,  gas,  heat,  air  conditioning,
       light, power, telephone, sewer, sprinkler charges and other utilities and
       services  used  on  or  from  the  Premises,  together  with  any  taxes,
       penalties,  surcharges or the like  pertaining  thereto,  and maintenance
       charges  for  utilities  and shall  furnish  all  electric  light  bulbs,
       ballasts and tubes.  If any such services are not  separately  metered to
       Tenant,  Tenant  shall pay a  reasonable  proportion,  as  determined  by
       Landlord,  of all charges jointly serving other premises.  Landlord shall
       not be liable for any damages  directly or indirectly  resulting from nor
       shall the Rent or any  monies  owed  Landlord  under  this  Lease  herein
       reserved  be  abated  by  reason  of:  (a)  the   installation,   use  or
       interruption  of  use  of any  equipment  used  in  connection  with  the
       furnishing of any such utilities or services;  (b) the failure to furnish
       or delay in furnishing  any such  utilities or services when such failure
       or delay is caused by acts of God or the elements,  labor disturbances of
       any  character,  or any other  accidents or other  conditions  beyond the
       reasonable  control  of  Landlord;  or (c) the  limitation,  curtailment,
       rationing or restriction on use of water,  electricity,  gas or any other
       form of energy or any other  service or utility  whatsoever  serving  the
       Premises or Project.  Landlord shall be entitled to cooperate voluntarily
       and in a reasonable  manner with the efforts of national,  state or local
       governmental  agencies or utility  suppliers in reducing  energy or other
       resource consumption. The obligation to make services available hereunder
       shall be subject to the  limitations  of any such  voluntary,  reasonable
       program.

SUBORDINATION

   16. Without the necessity of any additional document being executed by Tenant
       for the purpose of effecting a subordination, this Lease shall be subject
       and  subordinate  at all times to:  (a) all ground  leases or  underlying
       leases  which  may now  exist or  hereafter  be  executed  affecting  the
       Premises  and/or  the land  upon  which  the  Premises  and  Project  are
       situated,  or both;  and (b) any  mortgage or deed of trust which may now
       exist or be placed upon said Project,  land,  ground leases or underlying
       leases,  or  Landlord's  interest or estate in any of said items which is
       specified as security.  At the request of Tenant,  Landlord will endeavor
       to obtain  from the  secured  party  under any  mortgage or deed of trust
       which is senior  to this  Lease,  a  nondisturbance  agreement  upon such
       lender's customary form therefor. Notwithstanding the foregoing, Landlord
       shall have the right to subordinate or cause to be subordinated  any such
       ground  leases or underlying  leases or any such liens to this Lease.  In
       the event that any ground lease or underlying  lease  terminates  for any
       reason or any mortgage or deed of trust is  foreclosed or a conveyance in
       lieu of foreclosure is made for any reason, Tenant shall, notwithstanding
       any  subordination,  attorn to and become the Tenant of the  successor in
       interest to Landlord at the option of such successor in interest.  Within
       ten (10) days after request by Landlord, Tenant shall execute and deliver
       any  additional   documents   evidencing   Tenant's   attornment  or  the
       subordination  of this Lease with  respect to any such  ground  leases or
       underlying  leases or any such  mortgage  or deed of  trust,  in the form
       requested  by  Landlord  or  by  any  ground  landlord,   mortgagee,   or
       beneficiary under a deed of trust.

 FINANCIAL
STATEMENTS

   17. At the request of  Landlord,  Tenant shall  provide to Landlord  Tenant's
       current  financial  statement or other information  discussing  financial
       worth of Tenant  within  thirty  (30) days  after the date of  Landlord's
       request,  which  Landlord shall use solely for purposes of this Lease and
       in connection  with the  ownership,  management  and  disposition  of the
       Project.  So long as Tenant remains a publicly traded company,  Tenant is
       not in Default and Tenant files its public filings quarterly,  Tenant may
       comply  with the  provisions  of this  section by  submitting  its public
       filings to Landlord.

   ESTOPPEL
CERTIFICATE

   18. Tenant  agrees  from time to time,  within ten (10)  business  days after
       request of Landlord,  to deliver to Landlord,  or Landlord's designee, an
       estoppel  certificate  per  Exhibit  D or in an  alternate  form that the
       requesting party may require stating that this Lease is in full force and
       effect,  the date to which Rent has been paid,  the unexpired  portion of
       this Lease,  and such other  matters  pertaining  to this Lease as may be
       reasonably  requested  by Landlord.  Landlord and Tenant  intend that any
       statement  delivered pursuant to this Paragraph may be relied upon by any
       mortgagee, beneficiary, purchaser or prospective purchaser of the Project
       or any interest  therein.  The parties agree that Tenant's  obligation to
       furnish  such  estoppel  certificates  in a timely  fashion is a material
       inducement for Landlord's  execution of the Lease,  and shall be an Event
       of Default if Tenant  fails to fully  comply.  Tenant  acknowledges  that
       failure to provide the  Estoppel  Certificate  to Landlord or  Landlord's
       designee  within  the time  provided  above may cause  Landlord  to incur
       substantial  damages.  Tenant hereby agrees to indemnify Landlord for any
       liabilities,  losses,  costs,  damages  (including,  without  limitation,
       compensatory, incidental and consequential damages), injuries or expenses
       arising from

                                       10
<PAGE>

       the failure of Tenant to deliver the Estoppel certificate in the time and
       manner  provided in this  Paragraph.  In  addition to any other  remedies
       Landlord  may  have at law and  equity,  Landlord  shall be  entitled  to
       specific performance of this Paragraph.  The provisions of this Paragraph
       shall survive the expiration or termination of this Lease with respect to
       any  claims  or  liability   occurring   prior  to  such   expiration  or
       termination. Landlord agrees that in connection with any sale of Tenant's
       business,  stock offering, or financing,  but in no event more than twice
       in any calendar  year,  Tenant may request,  and Landlord will deliver to
       Tenant within fifteen (15) business days of Tenant's request, an estoppel
       certificate. Such certificate will state that this Lease is in full force
       and  effect,  the date on which Rent was last paid and any other  matters
       directly concerning this Lease which Tenant may reasonably request.

SECURITY
 DEPOSIT

   19. Tenant agrees to deposit with Landlord  upon  execution of this Lease,  a
       Security  Deposit  as stated in the Basic  Lease  Information,  which sum
       shall be held by Landlord,  without obligation for interest,  as security
       for the  performance  of Tenant's  covenants and  obligations  under this
       Lease. The Security Deposit is not an advance rental deposit or a measure
       of damages incurred by Landlord in case of Tenant's Default.  Landlord is
       not  required to keep all or any part of the  Security  Deposit  separate
       from its general accounts. Upon the occurrence of any Event of Default by
       Tenant,  Landlord may, from time to time,  without prejudice to any other
       remedy  provided  herein or provided by law,  use such fund to the extent
       necessary  to make  good any  arrears  of Rent or other  payments  due to
       Landlord hereunder,  and any other damage,  injury,  expense or liability
       caused by such Event of Default,  and Tenant  shall pay to  Landlord,  on
       demand, the amount so applied in order to restore the Security Deposit to
       its original  amount.  Although the Security  Deposit shall be deemed the
       property of Landlord,  any  remaining  balance of such  deposit  shall be
       returned  by Landlord  to Tenant at such time after  termination  of this
       Lease  that all of  Tenant's  obligations  under  this  Lease  have  been
       fulfilled. Landlord may use and commingle the Security Deposit with other
       funds of Landlord.  As additional security,  Tenant agrees to execute and
       deliver to Landlord a Uniform  Commercial  Code  Financing  Statement and
       Security agreement on all Trade Fixtures and improvements  otherwise made
       pursuant  to  Tenant's  Work  as  set  forth  in  Exhibit  B-1  in a form
       reasonably  satisfactory  to Landlord.  As an alternate to depositing the
       cash sum with  Landlord for the Security  Deposit,  Tenant may within six
       (6)  months  after  execution  of  this  Lease  deliver  to  Landlord  an
       unconditional  irrevocable  Letter of Credit in the amount of $227,500.00
       meeting the  requirements  of this  paragraph  (the  "Letter of Credit"),
       which shall secure the full and timely payment and  performance of all of
       Tenant's covenants and obligations under this Lease. The Letter of Credit
       shall (a)  designate  Landlord or its  assignees as  beneficiary,  (b) be
       issued by a financial  institution  approved by  Landlord,  (c) remain in
       full  force and  effect  during  the  entire  term of this  Lease and any
       extension  or holdover  period,  plus an  additional  period of three (3)
       months, and (d) be in form satisfactory to Landlord. The Letter of Credit
       may be for an initial  term of fifteen (15) months so long as it provides
       that  Landlord  may  immediately  draw the full  amount of the  Letter of
       Credit if the issuer does not give Landlord written notice of renewal for
       additional  successive  periods of twelve (12) months at least sixty (60)
       days prior to the expiration date.  Landlord is authorized to draw on the
       Letter of Credit from time to time in the event that (i) Landlord advises
       the issuer of the  Letter of Credit  that there is an Event of Default by
       Tenant under this Lease,  or (ii) the issuer gives  Landlord  notice that
       the  Letter of  Credit  will be  terminated  or will  expire  prior to it
       initial term of fifteen  (15)  months,  or (iii) the issuer does not give
       Landlord a written  notice of renewal of the term of the Letter of Credit
       as required by the preceding  sentence.  In the event Landlord shall draw
       on the Letter of Credit in the  circumstances  described in clause (i) of
       this paragraph,  Landlord shall be permitted to draw an amount  necessary
       in  Landlord's  good  faith  estimation  to fully  cure any such Event of
       Default,  including any damage,  injury,  expense or liability  caused or
       projected  to be caused by such Event of Default,  and Tenant  shall,  on
       demand  from  Landlord,  increase  the  Letter  of  Credit up to its full
       original amount. In the event Landlord shall draw on the Letter of Credit
       in the circumstances described in clause (ii) or (iii) of this paragraph,
       Landlord  shall be permitted  to draw the entire  amount of the Letter of
       Credit,  in which case such sum shall be held by Landlord as the Security
       Deposit  and  administered  as such.  Landlord  may draw on the Letter of
       Credit  regardless  of whether or not  Tenant  disputes  that an Event of
       Default  has  occurred  and  regardless  of any other  disputes or claims
       between  the  parties.  Landlord  shall not be  required  to deliver  any
       certifications  or  documentation  of any kind to the  issuer in order to
       make a draw, other than Landlord's  written demand.  The issuer shall not
       be  required  to conduct  any  inquiry  or  investigation  before  paying
       Landlord the requested amount of the draw. Landlord may assign,  transfer
       or pledge the Letter of Credit to any lender or purchaser  in  connection
       with any financing or sale of the Premises.

TENANT'S
REMEDIES

   20. The liability of Landlord to Tenant for any default by Landlord under the
       terms of this Lease are not personal obligations of the Landlord or other
       trustees,  advisors,  partners,  directors,  officers and shareholders of
       Landlord,  and Tenant agrees to look solely to Landlord's interest in the
       Project for the recovery of any amount from Landlord,  and shall not look
       to other assets of Landlord nor seek  recourse  against the assets of the
       Landlord or other trustees, advisors, partners,  directors,  officers and
       shareholders of Landlord.  Any lien obtained to enforce any such judgment
       and any levy of execution thereon shall be subject and subordinate to any
       lien, mortgage or deed of trust on the Project.

ASSIGNMENT
       AND
SUBLETTING

   21. A. General.  Tenant shall have the right to assign or sublet the Premises
       to any entity  resulting from a merger or  consolidation  with Tenant,  a
       public  offering and sale of some or all of Tenant's stock, a transfer of
       shares of Tenant's stock on the public stock  exchange,  or a transfer of
       the  Lease in  connection  with the sale of all or  substantially  all of
       Tenant's  assets,  provided that the entity which results from the merger
       or  consolidation  of  Tenant  has a net  equity of ten  million  dollars
       ($10,000,000.00).  Otherwise,  Tenant  shall not  assign  or  sublet  the
       Premises or any part thereof without  Landlord's prior written  approval.
       The right to assign  and/or sublet the Premises is personal to the Tenant
       and  shall  not  inure  to the  benefit  of any  assignee,  subtenant  or
       successor of Tenant.  If a Tenant  desires to assign this Lease,  it must
       present the Landlord with an ERISA  Certificate  in  compliance  with the
       provisions  of  Paragraph  37.  of this  Lease  signed  by the  potential
       assignee,  demonstrate  that the potential  assignee has adequate credit,
       demonstrate to the Landlord's  satisfaction that the potential assignee's
       proposed use of the Premises is compatible  with the Project and complies
       with all applicable laws,  ordinances,  rules and regulations.  If Tenant
       desires to assign this Lease or sublet any or all of the Premises, Tenant
       shall  give  Landlord  written  notice  ninety  (90)  days  prior  to the
       anticipated effective date of the assignment or sublease.  Landlord shall
       then have a period of thirty (30) days  following  receipt of such notice
       to notify Tenant in writing  whether  Landlord elects to permit Tenant to
       assign this Lease or sublet such space,  subject,  however, to Landlord's
       prior written  approval of the proposed  assignee or subtenant and of any
       related  documents  or  agreements  associated  with  the  assignment  or
       sublease. Landlord's consent to a proposed assignment or sublet shall not
       be unreasonably  withheld.  Without limiting the other instances in which
       it may be reasonable  for Landlord to withhold  Landlord's  consent to an
       assignment or subletting,  Landlord and Tenant  acknowledge that it shall
       be 

                                       11
<PAGE>

       reasonable for Landlord to withhold  Landlord's  consent in the following
       instances: The use of the Premises by such proposed assignee or subtenant
       would not be a permitted use or would increase the Parking Density of the
       Project;  the proposed  assignee or  subtenant is not of sound  financial
       condition,  as  determined  by  Landlord  after  receipt of the  proposed
       assignee's  financial  statements in form  satisfactory to Landlord;  the
       proposed  assignee or subtenant is a  governmental  agency;  the proposed
       assignee  or  subtenant  does not have a good  reputation  as a tenant of
       property;  the  proposed  assignee  or  subtenant  is a person  with whom
       Landlord is negotiating to lease space in the Project;  the assignment or
       subletting  would entail any alterations  which would lessen the value of
       the leasehold improvements in the Premises; or if Tenant is in Default of
       any obligation of Tenant under this Lease,  or Tenant has defaulted under
       this Lease on three (3) or more  occasions  during any twelve (12) months
       preceding the date that Tenant shall request consent. Failure by Landlord
       to approve a proposed assignee or subtenant shall not cause a termination
       of this Lease.

       B. Bonus Rent. Any Rent or other  consideration  realized by Tenant under
       any  approved  sublease  or  assignment  in  excess  of the Rent  payable
       hereunder,  after  Tenant's  actual  payment  of a  reasonable  brokerage
       commission,  reasonable  attorneys'  fees related to the  subletting  and
       reasonable costs of improving the subleased or assigned  premises for the
       subtenant's use in excess of costs  attributable to Tenant's Work,  shall
       be divided and paid, sixty (60%) -percent to Tenant,  forty (40%) percent
       to Landlord.  Notwithstanding  the foregoing,  when Tenant has invested a
       minimum of seventy dollars  ($70.00) per square foot,  excluding  related
       "soft costs" (as defined in Exhibit B-1), to improve the entire  Premises
       during the Lease Term, Tenant shall receive seventy-five (75%) percent of
       any bonus rent after  payment of a reasonable  brokerage  commission  and
       reasonable  attorneys' fee, and Landlord shall receive  twenty-five (25%)
       percent of such bonus rent.

       C.  Corporation.  If Tenant is a  corporation,  a transfer  of  corporate
       shares by sale,  assignment,  bequest,  inheritance,  operation of law or
       other  disposition  (including  such a transfer  to or by a  receiver  or
       trustee in federal or state bankruptcy, insolvency or other proceedings),
       so as to result in a change in the present control of such corporation or
       any of its parent corporations by the person or persons owning a majority
       of said corporate shares,  shall constitute an assignment for purposes of
       this Lease.

       D.  Partnership.  If  Tenant is a  partnership,  joint  venture  or other
       incorporated business form, a transfer of the interest of persons,  firms
       or  entities  responsible  for  managerial  control  of  Tenant  by sale,
       assignment, bequest, inheritance,  operation of law or other disposition,
       so as to result in a change in the present  control of said entity and/or
       a change in the  identity  of the  persons  responsible  for the  general
       credit  obligations of said entity shall constitute an assignment for all
       purposes of this Lease.

       E. Liability.  No assignment or subletting by Tenant shall relieve Tenant
       of any obligation  under this Lease.  Any assignment or subletting  which
       conflicts with the provisions hereof shall be void.

       F. Options.  Tenant must be in possession of the entire Premises in order
       to exercise its options to renew and/or expand under this Lease.

 AUTHORITY
OF PARTIES

   22. Landlord  represents and warrants that it has full right and authority to
       enter  into  this  Lease and to  perform  all of  Landlord's  obligations
       hereunder.  Tenant  represents  and  warrants  that it has full right and
       authority  to enter  into  this  Lease  and to  perform  all of  Tenant's
       obligations hereunder.

CONDEMNATION

   23. A. Condemnation Resulting in Termination. If the whole or any substantial
       part of the Project of which the  Premises  are a part should be taken or
       condemned  for any  public  use  under  governmental  law,  ordinance  or
       regulation, or by right of eminent domain, or by private purchase in lieu
       thereof,  and the taking would prevent or materially  interfere  with the
       Permitted  Use of the Premises,  this Lease shall  terminate and the Rent
       shall be abated  during the  unexpired  portion of this Lease,  effective
       when the physical taking of said Premises shall have occurred.

       B. Condemnation Not Resulting in Termination. If a portion of the Project
       of which the  Premises  are a part should be taken or  condemned  for any
       public use under any governmental law,  ordinance,  or regulation,  or by
       right of eminent domain, or by private purchase in lieu thereof, and this
       Lease is not terminated as provided in Paragraph 23.A.  above, this Lease
       shall not terminate,  but the Rent payable hereunder during the unexpired
       portion of the Lease  shall be  reduced,  beginning  on the date when the
       physical  taking shall have  occurred,  to such amount as may be fair and
       reasonable under all of the circumstances.

       C. Award.  Landlord  shall be entitled  to any and all  payment,  income,
       rent, award, or any interest therein whatsoever which may be paid or made
       in  connection  with such taking or  conveyance  and Tenant shall have no
       claim  against  Landlord  or  otherwise  for the  value of any  unexpired
       portion of this Lease.  Notwithstanding  the foregoing,  any compensation
       specifically  awarded  Tenant  for loss of  business,  Tenant's  personal
       property,  moving  costs or loss of  goodwill,  shall be and  remain  the
       property of Tenant.

CASUALTY
  DAMAGE

   24. A.  General.  If the  Premises  or the  Building  should  be  damaged  or
       destroyed by fire,  tornado,  earthquake or other casualty,  Tenant shall
       give immediate  written  notice  thereof to Landlord.  Within thirty (30)
       days after  Landlord's  receipt of such  notice,  Landlord  shall  notify
       Tenant whether in Landlord's  opinion such repairs can reasonably be made
       either:  (1) within  ninety (90) days;  (2) in more than ninety (90) days
       but in less than one hundred  eighty (180) days;  or (3) in more than one
       hundred  eighty  (180)  days  from  the date of such  notice.  Landlord's
       determination shall be binding on Tenant.

       B. Less Than 90 Days.  If the Premises or the Building  should be damaged
       by fire,  tornado,  earthquake or other  casualty but only to such extent
       that  rebuilding  or repairs can in  Landlord's  estimation be reasonably
       completed  within  ninety (90) days after the date of such  damage,  this
       Lease shall not  terminate,  and  provided  that  insurance  proceeds are
       available to fully repair the damage,  Landlord  shall proceed to rebuild
       and repair the Premises in the manner determined by Landlord, except that
       Landlord shall not be required to rebuild,  repair or replace any part of
       the  partitions,  Fixtures,  additions and other  leasehold  improvements
       which may have been placed in, on or about the Premises.  If the Premises
       are  untenantable  in whole or in part  following  such damage,  the Rent
       payable hereunder during the period in which they are untenantable  shall
       be abated proportionately,  but only to the extent the Premises are unfit
       for occupancy.

                                       12
<PAGE>

       C.  Greater  Than 90 Days.  If the  Premises  or the  Building  should be
       damaged by fire,  tornado,  earthquake or other casualty but only to such
       extent  that  rebuilding  or  repairs  can in  Landlord's  estimation  be
       reasonably  completed  in more than ninety (90) days but in less than one
       hundred eighty (180) days, then Landlord shall have the option of either:
       (1)  terminating  the Lease  effective upon the date of the occurrence of
       such damage, in which event the Rent shall be abated during the unexpired
       portion of the Lease;  or (2)  electing to rebuild or repair the Premises
       to  substantially  the  condition  in which  they  existed  prior to such
       damage,  provided that insurance proceeds are available,  to fully repair
       the damage, except that Landlord shall not be required to rebuild, repair
       or replace  any part of the  partitions,  Fixtures,  additions  and other
       improvements which may have been placed in, on or about the Premises.  If
       the Premises are  untenantable in whole or in part following such damage,
       the  Rent  payable   hereunder  during  the  period  in  which  they  are
       untenantable shall be abated proportionately,  but only to the extent the
       Premises are unfit for occupancy.  In the event that Landlord should fail
       to complete such repairs and  rebuilding  within one hundred  eighty days
       (180) days after the date upon which  Landlord  is  notified by Tenant of
       such damage,  such period of time to be extended for delays caused by the
       fault or  neglect  of Tenant or  because  of acts of God,  acts of public
       agencies,  labor disputes,  strikes,  fires, freight embargoes,  rainy or
       stormy  weather,  inability to obtain  materials,  supplies or fuels,  or
       delays  of the  contractors  or  subcontractors  or any  other  causes or
       contingencies  beyond the reasonable  control of Landlord,  Tenant may at
       Tenant's  option  within ten (10) days after the  expiration  of such one
       hundred eighty (180) day period (as such may be extended), terminate this
       Lease by delivering written notice of termination to Landlord as Tenant's
       exclusive  remedy,   whereupon  all  rights  hereunder  shall  cease  and
       terminate thirty (30) days after  Landlord's  receipt of such termination
       notice.

       D.  Greater Than 180 Days.  If the Premises or the Building  should be so
       damaged by fire, tornado, earthquake or other casualty that rebuilding or
       repairs cannot in Landlord's  estimation be completed  within one hundred
       eighty (180) days after such damage,  this Lease shall  terminate and the
       Rent  shall  be  abated  during  the  unexpired  portion  of this  Lease,
       effective upon the date of the occurrence of such damage.

       E. Tenant's  Fault.  If the Premises or any other portion of the Building
       is  damaged  by  fire  or  other  casualty   resulting  from  the  fault,
       negligence, or breach of this Lease by Tenant or any of Tenant's Parties,
       Base Rent and Additional  Rent shall not be diminished  during the repair
       of such damage and Tenant  shall be liable to  Landlord  for the cost and
       expense of the repair and  restoration of the Building  caused thereby to
       the extent such cost and expense is not covered by insurance proceeds.

       F. Uninsured Casualty.  Notwithstanding  anything herein to the contrary,
       in the event that the  Premises or the  Building is damaged or  destroyed
       and are not fully covered by the insurance  proceeds received by Landlord
       or in the event that the holder of any indebtedness secured by a mortgage
       or deed of trust  covering  the  Premises  requires  that  the  insurance
       proceeds be applied to such  indebtedness,  then in either case  Landlord
       shall have the right to terminate this Lease by delivering written notice
       of termination to Tenant within thirty (30) days after the date of notice
       to  Landlord  that said  damage or  destruction  is not fully  covered by
       insurance or such requirement is made by any such holder, as the case may
       be,  whereupon  all  rights and  obligations  hereunder  shall  cease and
       terminate.

       G. Waiver.  Except as otherwise  provided in this Paragraph  24.,  Tenant
       hereby waives the provisions of Sections 1932(a),  1933(4), 1941 and 1942
       of the Civil Code of California.

HOLDING
   OVER

   25. If Tenant shall retain  possession of the Premises or any portion thereof
       without  Landlord's  consent  following  the  expiration  of the Lease or
       sooner termination for any reason,  then Tenant shall pay to Landlord for
       each day of such  retention  one hundred and fifty (150%)  percent of the
       amount of the  daily  rental  as of the last  month  prior to the date of
       expiration or termination.  Tenant shall also indemnify,  defend, protect
       and hold Landlord  harmless from any loss,  liability or cost,  including
       reasonable   attorneys'   fees,   resulting   from  delay  by  Tenant  in
       surrendering the Premises, including, without limitation, any claims made
       by any  succeeding  tenant  founded on such delay.  Acceptance of Rent by
       Landlord  following  expiration  or  termination  shall not  constitute a
       renewal of this Lease, and nothing  contained in this Paragraph 25. shall
       waive  Landlord's  right of reentry or any other right.  Unless  Landlord
       consents  in writing to Tenant's  holding  over,  Tenant  shall be only a
       Tenant at  sufferance,  whether  or not  Landlord  accepts  any Rent from
       Tenant while Tenant is holding over without  Landlord's  written consent.
       Additionally, in the event that upon termination of the Lease, Tenant has
       not fulfilled its  obligation  with respect to repairs and cleanup of the
       Premises or any other Tenant obligations as set forth in this Lease, then
       Landlord shall have the right to perform any such obligations as it deems
       necessary  at Tenant's  sole cost and expense,  and any time  required by
       Landlord to complete  such  obligations  shall be  considered a period of
       holding over and the terms of this Paragraph 25. shall apply.

DEFAULT

   26. A.  Events of  Default.  The  occurrence  of any of the  following  shall
       constitute  an event of default  ("Event of Default" or "Default") on the
       part of Tenant:

       (1) Abandonment.  Abandonment of the Premises for a continuous  period in
       excess  of five (5)  business  days.  Tenant  waives  any right to notice
       Tenant  may have under  Section  1951.3 of the Civil Code of the State of
       California, the terms of this Paragraph 26.A. being deemed such notice to
       Tenant as required by said Section 1951.3.

       (2)  Nonpayment of Rent.  Failure to pay any  installment  of Rent or any
       other amount due and payable hereunder when said payment is due.

       (3) Other  Obligations.  Failure to perform any obligation,  agreement or
       covenant  under  this  Lease  other  than  those  matters   specified  in
       subparagraphs   (1)  and  (2)  of  this  Paragraph  26.A.,  such  failure
       continuing for fifteen (15) days after written notice of such failure. In
       the event  Tenant has  commenced  to cure the Default  within the fifteen
       (15) day  period,  but has not  completed  the  cure,  so long as  Tenant
       diligently  pursues  the  cure  to  completion,  Tenant  shall  not be in
       Default.

       (4) General Assignment. A general assignment by Tenant for the benefit of
       creditors.

       (5)  Bankruptcy.  The filing of any  voluntary  petition in bankruptcy by
       Tenant, or the filing of an involuntary  petition by Tenant's  creditors,
       which  involuntary  petition  remains  undischarged for a period of sixty
       (60)  days.  In the  event  that  under  applicable  law the  trustee  in
       bankruptcy  or Tenant has the right to affirm this Lease and  continue to
       perform  the  obligations  of Tenant  hereunder,  such  trustee or Tenant
       shall,  in such time period as may be permitted by the  bankruptcy  court
       having jurisdiction, cure all Defaults of Tenant hereunder

                                       13
<PAGE>

       outstanding as of the date of the affirmance of this Lease and provide to
       Landlord such adequate  assurances as may be necessary to ensure Landlord
       of the continued performance of Tenant's obligations under this Lease .

       (6)  Receivership.  The  employment  of a receiver to take  possession of
       substantially all of Tenant's assets or the Premises, if such appointment
       remains  undismissed  or  undischarged  for a period of thirty  (30) days
       after the order therefor.

       (7) Attachment.  The attachment,  execution or other judicial  seizure of
       all or  substantially  all of Tenant's  assets or the  Premises,  if such
       attachment or other seizure  remains  undismissed or  undischarged  for a
       period of thirty (30) days after the levy thereof.

       (8) Delays.  Any delay in the  construction  of Landlord's Work caused by
       Tenant or Tenant's Work as provided in Exhibit B-1.

       B.  Remedies Upon Default.

       (1) Termination.  In the event of the occurrence of any Event of Default,
       Landlord  shall  have the right to give a written  termination  notice to
       Tenant,  and on the date  specified  in such  notice,  Tenant's  right to
       possession shall  terminate,  and this Lease shall terminate unless on or
       before  such date all  arrears of rental  and all other  sums  payable by
       Tenant under this Lease and all reasonable costs and expenses incurred by
       or on behalf of Landlord hereunder shall have been paid by Tenant and all
       other  Events of  Default  of this  Lease by Tenant at the time  existing
       shall have been fully remedied to the  satisfaction  of Landlord.  At any
       time after such  termination,  Landlord  may  recover  possession  of the
       Premises or any part  thereof and expel and remove  therefrom  Tenant and
       any other  person  occupying  the same,  by any lawful  means,  and again
       repossess and enjoy the Premises without prejudice to any of the remedies
       that Landlord may have under this Lease, or at law or equity by reason of
       Tenant's Default or of such termination.

       (2) Continuation After Default.  Even though an Event of Default may have
       occurred,  this Lease  shall  continue  in effect for so long as Landlord
       does not terminate  Tenant's right to possession under Paragraph 26.B.(1)
       hereof,  and Landlord may enforce all of  Landlord's  rights and remedies
       under this Lease, including without limitation, the right to recover Rent
       as it becomes due, and  Landlord,  without  terminating  this Lease,  may
       exercise  all of the rights and  remedies  of a  landlord  under  Section
       1951.4 of the Civil Code of the State of California or any successor code
       section.  Acts of  maintenance,  preservation  or  efforts  to lease  the
       Premises or the appointment of a receiver upon application of Landlord to
       protect  Landlord's  interest  under this Lease shall not  constitute  an
       election to terminate Tenant's right to possession.

       C. Damages After Default.  Should Landlord  terminate this Lease pursuant
       to the provisions of Paragraph  26.B.(1) hereof,  Landlord shall have the
       rights and remedies of a Landlord provided by Section 1951.2 of the Civil
       Code of the State of California,  or successor  code sections.  Upon such
       termination,  in  addition  to any other  rights  and  remedies  to which
       Landlord may be entitled under applicable law, Landlord shall be entitled
       to recover from Tenant:  (1) the worth at the time of award of the unpaid
       Rent and other amounts which had been earned at the time of  termination,
       (2) the worth at the time of award of the amount by which the unpaid Rent
       which would have been earned  after  termination  until the time of award
       exceeds the amount of such Rent loss that Tenant  proves  could have been
       reasonably  avoided;  (3) the worth at the time of award of the amount by
       which the unpaid Rent for the balance of the Term after the time of award
       exceeds  the  amount of such Rent loss that the  Tenant  proves  could be
       reasonably  avoided;  and (4) any other amount  necessary  to  compensate
       Landlord for all the detriment  proximately caused by Tenant's failure to
       perform Tenant's  obligations  under this Lease or which, in the ordinary
       course of things, would be likely to result therefrom.  The "worth at the
       time of award" of the amounts  referred to in (1) and (2), above shall be
       computed  at the lesser of the "prime  rate," as  announced  from time to
       time by Wells  Fargo,  N.A.  (San  Francisco)  plus  five (5)  percentage
       points, or the maximum interest rate allowed by law ("Applicable Interest
       Rate"). The "worth at the time of award" of the amount referred to in (3)
       above  shall be  computed  by  discounting  such  amount  at the  Federal
       Discount Rate of the Federal Reserve Bank of San Francisco at the time of
       the award plus one (1%) percent.  If this Lease  provides for any periods
       during the Term during  which  Tenant is not required to pay Base Rent or
       if Tenant otherwise receives a Rent concession,  then upon the occurrence
       of an Event of Default,  Tenant  shall owe to Landlord the full amount of
       such Base Rent or value of such Rent  concession,  plus  interest  at the
       Applicable Interest Rate, calculated from the date that such Base Rent or
       Rent concession would have been payable.

       D. Late Charge.  If any  installment  of Rent is not paid within five (5)
       business  days from the date when due, such amount shall bear interest at
       the Applicable Interest Rate from the date on which said payment shall be
       due until the date on which  Landlord  shall  receive  said  payment.  In
       addition,  Tenant  shall pay  Landlord a late  charge  equal to five (5%)
       percent of the  delinquency,  to compensate  Landlord for the loss of the
       use of the amount  not paid and the  administrative  costs  caused by the
       delinquency,  the parties  agreeing that  Landlord's  damage by virtue of
       such  delinquencies  would be difficult to compute and the amount  stated
       herein represents a reasonable estimate thereof. This provision shall not
       relieve Tenant of Tenant's  obligation to pay Rent at the time and in the
       manner herein specified.

       E. Remedies Cumulative.  All rights, privileges and elections or remedies
       of the  parties  are  cumulative  and  not  alternative,  to  the  extent
       permitted by law and except as otherwise provided herein.

LIENS

   27. Tenant shall keep the Premises  free from liens arising out of or related
       to  work  performed,  materials  or  supplies  furnished  or  obligations
       incurred by Tenant or in connection  with work made,  suffered or done by
       or on behalf of Tenant in or on the  Premises  or  Project.  In the event
       that  Tenant  shall not,  within ten (10)  business  days  following  the
       imposition  of any such lien,  cause the same to be released of record by
       payment or posting of a proper bond,  Landlord shall have, in addition to
       all other  remedies  provided  herein and by law, the right,  but not the
       obligation,  to cause the same to be  released  by such means as Landlord
       shall deem  proper,  including  payment of the claim  giving rise to such
       lien.  All sums paid by  Landlord  on behalf of Tenant  and all  expenses
       incurred by Landlord in connection  therefor shall be payable to Landlord
       by  Tenant on demand  with  interest  at the  Applicable  Interest  Rate.
       Landlord shall have the right at all times to post and keep posted on the
       Premises  any notices  permitted  or  required by law, or which  Landlord
       shall deem proper,  for the  protection of Landlord,  the  Premises,  the
       Project and any other party having an interest  therein,  from mechanics'
       and materialmen's liens, and Tenant shall give Landlord not less than ten
       (10) business days

                                       14
<PAGE>

       prior written notice of the  commencement  of any work in the Premises or
       Project  which  could  lawfully  give rise to a claim for  mechanics'  or
       materialmen's liens.

TRANSFERS
       BY
 LANDLORD

   28. In the event of a sale or  conveyance  by Landlord of the Building or the
       Project or a  foreclosure  by any  creditor of  Landlord,  the same shall
       operate to release  Landlord from any liability upon any of the covenants
       or conditions,  express or implied,  herein contained in favor of Tenant,
       to the extent  required  to be  performed  after the  passing of title to
       Landlord's  successor-in-interest.  In such event,  Tenant agrees to look
       solely to the  responsibility  of the  successor-in-interest  of Landlord
       under this Lease with respect to the  performance  of the  covenants  and
       duties  of  "Landlord"  to be  performed  after the  passing  of title to
       Landlord's successor-in-interest. This Lease shall not be affected by any
       such sale and  Tenant  agrees to attorn  to the  purchaser  or  assignee.
       Landlord's  successor(s)-in-interest  shall not have  liability to Tenant
       with  respect  to the  failure  to  perform  all of  the  obligations  of
       "Landlord", to the extent required to be performed prior to the date such
       successor(s)-in-interest became the owner of the Building.

  RIGHT OF
  LANDLORD
TO PERFORM
  TENANT'S
 COVENANTS

   29. All covenants  and  agreements to be performed by Tenant under any of the
       terms of this Lease shall be  performed  by Tenant at Tenant's  sole cost
       and expense and without any  abatement  of Rent.  If Tenant shall fail to
       pay any sum of money,  other  than Base  Rent and Basic  Operating  Cost,
       required  to be paid by Tenant  hereunder  or shall fail to  perform  any
       other act on Tenant's  part to be performed  hereunder,  and such failure
       shall  continue  for five (5) days  after  notice  thereof  by  Landlord,
       Landlord may, but shall not be obligated to do so, and without waiving or
       releasing Tenant from any obligations of Tenant, make any such payment or
       perform any such act on Tenant's part to be made or performed.  All sums,
       so paid by Landlord and all  necessary  incidental  costs  together  with
       interest  thereon at the  Applicable  Interest Rate from the date of such
       payment by Landlord  shall be payable to  Landlord on demand,  and Tenant
       covenants to pay such sums,  and Landlord  shall have, in addition to any
       other  right or remedy of  Landlord,  the same right and  remedies in the
       event of the  non-payment  thereof by Tenant as in the case of Default by
       Tenant in the payment of Base Rent and Basic Operating Cost.

WAIVER

   30. If either Landlord or Tenant waives the performance of any term, covenant
       or condition  contained in this Lease, such waiver shall not be deemed to
       be a waiver  of any  subsequent  breach  of the same or any  other  term,
       covenant  or  condition  contained  herein.  The  acceptance  of  Rent by
       Landlord shall not constitute a waiver of any preceding  breach by Tenant
       of  any  term,  covenant  or  condition  of  this  Lease,  regardless  of
       Landlord's  knowledge  of such  preceding  breach  at the  time  Landlord
       accepted  such Rent.  Failure by  Landlord  to enforce  any of the terms,
       covenants or conditions of this Lease for any length of time shall not be
       deemed to waive or to decrease the right of Landlord to insist thereafter
       upon  strict  performance  by  Tenant.  Waiver by  Landlord  of any term,
       covenant  or  condition  contained  in this  Lease  may only be made by a
       written document signed by Landlord.

NOTICES

   31. Each  provision  of this Lease or of any  applicable  governmental  laws,
       ordinances, regulations and other requirements with reference to sending,
       mailing  or  delivery  of any  notice  or the  making of any  payment  by
       Landlord or Tenant to the other shall be deemed to be complied  with when
       and if the following steps are taken:

       A. Rent.  All Rent and other  payments  required  to be made by Tenant to
       Landlord  hereunder shall be payable to Landlord at the address set forth
       in the Basic Lease Information,  or at such other address as Landlord may
       specify  from time to time by  written  notice  delivered  in  accordance
       herewith.  Tenant's  obligation  to pay Rent  and any  other  amounts  to
       Landlord  under the  terms of this  Lease  shall not be deemed  satisfied
       until  such  Rent and  other  amounts  have  been  actually  received  by
       Landlord.

       B. Other. All notices,  demands,  consents and approvals which may or are
       required to be given by either party to the other  hereunder  shall be in
       writing and either  personally  delivered,  sent by commercial  overnight
       courier, sent by facsimile, or mailed,  certified or registered,  postage
       prepaid,  and  addressed  to the party to be  notified at the address for
       such party as specified in the Basic Lease  Information  or to such other
       place as the party to be notified  may from time to time  designate by at
       least fifteen (15) days notice to the notifying  party.  Notices shall be
       deemed served upon receipt or refusal to accept delivery. Tenant appoints
       as its agent to receive the service of all default  notices and notice of
       commencement of unlawful detainer  proceedings the person in charge of or
       apparently in charge of occupying the Premises at the time, and, if there
       is no such person, then such service may be made by attaching the same on
       the main entrance of the Premises.

ATTORNEYS'
      FEES

   32. In the event that Landlord  places the  enforcement of this Lease, or any
       part  thereof,  or the  collection  of any Rent  due,  or to  become  due
       hereunder,  or recovery of  possession of the Premises in the hands of an
       attorney,   Tenant  shall  pay  to  Landlord,  upon  demand,   Landlord's
       reasonable  attorneys' fees and court costs. In any action which Landlord
       or  Tenant  brings  to  enforce  its  respective  rights  hereunder,  the
       unsuccessful  party shall pay all costs incurred by the prevailing  party
       including reasonable  attorneys' fees, to be fixed by the court, and said
       costs and attorneys' fees shall be a part of the judgment in said action.

 SUCCESSORS
AND ASSIGNS

   33. This Lease shall be binding  upon and inure to the  benefit of  Landlord,
       its  successors  and assigns,  and shall be binding upon and inure to the
       benefit of  Tenant,  its  successors,  and to the  extent  assignment  is
       approved by Landlord hereunder, Tenant's assigns.

  FORCE
MAJEURE

   34. In the event that  Landlord  shall be delayed,  hindered in or  prevented
       from the  performance of any act or obligation  required under this Lease
       by reason of acts of God, strikes,  lockouts, labor troubles or disputes,
       inability to procure or shortage of materials or labor,  failure of power
       or utilities, delay in transportation,  fire, vandalism, accident, flood,
       severe weather,  other  casualty,  governmental  requirements  (including
       mandated  changes  in the plans and  specifications  of  Landlord's  Work
       resulting  from  changes  in  pertinent   governmental   requirements  or
       interpretations thereof), riot, insurrection,  civil commotion, sabotage,
       explosion,  war, natural or local emergency, acts or omissions of others,
       including  Tenant, or other reasons of a similar or dissimilar nature not
       solely  the  fault  of,  or under  the  exclusive  control  of,  Landlord
       (individually  and collectively,  "Force  Majeure"),  then performance of
       such act or  obligation  shall be excused for the period of the delay and
       the period for the  performance of any such act or  obligations  shall be
       extended for the period equivalent to the period of such delay.

                                       15
<PAGE>

 BROKERAGE
COMMISSION

   35. Landlord shall pay a brokerage  commission to Broker in accordance with a
       separate  agreement  between  Landlord  and  Broker.  Tenant  warrants to
       Landlord that Tenant's sole contact with Landlord or with the Premises in
       connection  with this  transaction  has been  directly  with Landlord and
       Broker,  and that no other broker or finder can properly claim a right to
       a commission or a finder's fee based upon  contacts  between the claimant
       and Tenant  with  respect  to  Landlord  or the  Premises.  Tenant  shall
       indemnify,  defend by counsel  acceptable  to Landlord,  protect and hold
       Landlord harmless from and against any loss, cost or expense,  including,
       but not limited to,  attorneys' fees and costs,  resulting from any claim
       for a fee or commission  by any broker or finder in  connection  with the
       Premises and this Lease other than Broker. Likewise, Landlord warrants to
       Tenant that  Landlord's  sole contact with Tenant or withthe  Premises in
       connection  with this  transaction  has been  directly  with  Tenant  and
       Broker,  and that no other broker or finder can properly claim a right to
       a commission or a finder's fee based upon  contacts  between the claimant
       and Landlord with respect to Tenant or the Premises. Landlord also agrees
       to  indemnify  Tenant for any loss,  cost or expense,  including  but not
       limited to, attorneys' fees and costs, resulting from any claim for a fee
       or commission  by any broker or finder  alleging a course of conduct with
       Landlord  in  connection  with the  Premises  and this  Lease  other than
       Broker.

MISCELLANEOUS

   36. A. General.  The term "Tenant" or any pronoun used in place thereof shall
       indicate and include the  masculine  or feminine,  the singular or plural
       number,  individuals,   firms  or  corporations,   and  their  respective
       successors, executors, administrators and permitted assigns, according to
       the context hereof.

       B.  Time.  Time is of the  essence  regarding  this  Lease and all of its
       provisions.

       C.  Choice of Law.  This Lease  shall in all  respects be governed by the
       laws of the State of California.

       D. Entire Agreement. This Lease, together with its exhibits, contains all
       the  agreements  of  the  parties  hereto  and  supersedes  any  previous
       negotiations.  There have been no representations made by the Landlord or
       understandings  made  between the  parties  other than those set forth in
       this Lease and its exhibits.

       E.  Modification.  This  Lease  may not be  modified  except by a written
       instrument signed by the parties hereto.

       F.  Severability.  If, for any reason  whatsoever,  any of the provisions
       hereof shall be unenforceable or ineffective, all of the other provisions
       shall be and remain in full force and effect.

       G.  Recordation.  Tenant  shall not  record  this  Lease or a short  form
       memorandum hereof.

       H.  Examination  of Lease.  Submission  of this Lease to Tenant  does not
       constitute  an option or offer to lease and this  Lease is not  effective
       otherwise until execution and delivery by both Landlord and Tenant.

       I. Accord and Satisfaction.  No payment by Tenant of a lesser amount than
       the Rent nor any  endorsement  on any  check or letter  accompanying  any
       check or payment of Rent  shall be deemed an accord and  satisfaction  of
       full  payment of Rent,  and  Landlord  may accept  such  payment  without
       prejudice to  Landlord's  right to recover the balance of such Rent or to
       pursue other remedies.

       J.  Easements.  Landlord may grant  easements on the Project and dedicate
       for public use portions of the Project without Tenant's consent; provided
       that no such  grant or  dedication  shall  substantially  interfere  with
       Tenant's  use of the  Premises.  Upon  Landlord's  demand,  Tenant  shall
       execute, acknowledge and deliver to Landlord documents, instruments, maps
       and plats necessary to effectuate Tenant's covenants hereunder.

       K. Drafting and Determination  Presumption.  The parties acknowledge that
       this Lease has been agreed to by both the parties, that both Landlord and
       Tenant have  consulted  with  attorneys with respect to the terms of this
       Lease and that no presumption  shall be created against  Landlord because
       Landlord drafted this Lease.  Except as otherwise  specifically set forth
       in this Lease,  with respect to any consent,  determination or estimation
       of Landlord  required in this Lease or requested of Landlord,  Landlord's
       consent,  determination  or estimation  shall be made in Landlord's  good
       faith opinion, whether objectively reasonable or unreasonable.

       L. Exhibits. Exhibits A through E attached hereto are hereby incorporated
       herein by this reference.

       M. No Light,  Air or View  Easement.  Any  diminution  or shutting off of
       light,  air or  view by any  structure  which  may be  erected  on  lands
       adjacent  to or in the  vicinity of the  Building  shall in no way affect
       this Lease or impose any liability on Landlord.

       N. No Third Party Benefit.  This Lease is a contract between Landlord and
       Tenant and nothing herein is intended to create any third party benefit.

       O. Waiver of Jury Trial. IF ANY ACTION OR PROCEEDING BETWEEN LANDLORD AND
       TENANT TO ENFORCE THE  PROVISIONS  OF THIS LEASE  (INCLUDING AN ACTION OR
       PROCEEDING BETWEEN LANDLORD AND THE TRUSTEE OR DEBTOR IN POSSESSION WHILE
       TENANT IS A DEBTOR IN A PROCEEDING  UNDER ANY BANKRUPTCY LAW) PROCEEDS TO
       TRIAL, LANDLORD AND TENANT HEREBY WAIVE THEIR RESPECTIVE RIGHTS TO A JURY
       IN SUCH TRIAL.  Landlord and Tenant agree that this Paragraph constitutes
       a written  consent  to  waiver of trial by jury  within  the  meaning  of
       California Code of Civil  Procedure  Section  631(a)(2),  and Tenant does
       hereby  authorize and empower Landlord to file this Paragraph and or this
       Lease,  as  required,  with the clerk or judge of any court of  competent
       jurisdiction as a written consent to waiver of jury trial.

       P. Covenant of Quiet Enjoyment. So long as Tenant is not in Default under
       this Lease,  Tenant has the right to occupy and enjoy the Premises during
       the Term of this Lease in peace and without  disturbance from Landlord or
       any other party subject to Landlord's supervision or control.

ADDITIONAL
PROVISIONS

   37. A. ERISA  Representations.  Tenant  represents  to Landlord that with the
       exception  of this  Lease,  neither the Tenant nor any  affiliate  of the
       Tenant is a tenant  under a lease or any other  tenancy  arrangement  (1)
       with (a) Riggs& Company,  a division of Riggs Bank N.A., a trustee of the
       Multi-Employer  Property  Trust;  (b) Riggs Bank  N.A.,  a trustee of the
       Multi-Employer Property Trust; (c) the Multi-Employer Property Trust; (d)
       the

                                       16
<PAGE>

       National Bank of Washington  Multi-Employer  Property Trust, the previous
       name of the Multi-Employer Property Trust; (e) The Riggs National Bank of
       Washington,  D.C., as trustee of the  Multi-Employer  Property Trust; (f)
       the Harman International Business Campus Joint Venture; (g) the Corporate
       Drive Corporation as trustee of the Corporate Drive Nominee Realty Trust;
       (h) Goldbelt  Place Joint  Venture;  (i)  Arboretum  Lakes-1,  L.L.C.,  a
       Delaware limited liability company;  (j) Village Green of Rochester Hills
       Associates L.L.C., a Michigan limited liability company;  (k) Pine Street
       Development,  L.L.C., a Washington  limited liability  company;  (l) MEPT
       Realty LLC, a New York limited  liability  company;  (m) MEPT,  L.L.C., a
       Delaware  limited  liability  company;  (n)  Cabrillo  Properties  LLC, a
       Delaware  limited  liability  company;  (o) Valencia  L.L.C.,  a Delaware
       limited liability company;  or (p) Mission Trails LLC, a Delaware limited
       liability company; or (2) involving any property in which any one or more
       of the  entities  named in clauses  (1)(a)  through  (p) are known by the
       Tenant to have an ownership interest.

       B.  Anti-Discrimination.  There  shall be no  discrimination  against  or
       segregation of any person or group of persons, on account of race, color,
       creed,  religion,  sex, marital status,  national origin, or ancestry, in
       the  leasing,  subleasing,   transferring,   use,  occupancy,  tenure  or
       enjoyment of the Premises, nor shall the Landlord or Tenant or any person
       claiming under or through the Landlord or Tenant, establish or permit any
       such  practice  or  practices  of   discrimination  or  segregation  with
       reference  to  the  selection,  location,  number,  use or  occupancy  of
       tenants, sublessees, subtenants, or vendees in the Premises.

       C.  Landlord's  Assignment.  Landlord shall have the right to assign this
       Lease,   and  upon  such  assignment   Landlord  shall  have  no  further
       obligations, duties under this Lease, or liabilities hereunder.

       D. Right of First Offer.  Landlord is currently under contract to acquire
       and  intends to develop a second  phase of the  Project  ("Phase  II") as
       depicted in Exhibit  A-3. In the event that during the term of this Lease
       Landlord obtains a controlling  interest in Phase II and provided that as
       of such date there is no act or omission  of Tenant  that would  become a
       Default  with the passage of time or the giving of notice,  Tenant  shall
       have a one-time  right of first offer  ("Right of First  Offer") to lease
       all or a  portion  of  space  in the  approximately  40,000  square  foot
       building  proposed in Phase II which the Right of First Offer shall be on
       the  terms  and  conditions  set forth in this  section.  Landlord  shall
       provide Tenant with written notice  ("First-Offer  Notice") when Landlord
       determines  at  Landlord's  sole  discretion  that  Phase II will  become
       available  for lease to third  parties.  Provided  that  Tenant is not in
       Default  as of the time of  exercise  of the  Right of First  Offer,  and
       provided  that as of such date there is no act or omission of Tenant that
       would  become a Default with the passage of time or the giving of notice,
       if Tenant  wishes to  exercise  its Right of First  Offer,  Tenant  shall
       within ten (10) days after delivery of the First-Offer  Notice to Tenant,
       deliver written notice to Landlord of its intention to exercise its Right
       of First Offer on available  Phase II space.  While Tenant may lease less
       than all available  space, the unleased portion must be of adequate size,
       as determined by Landlord, to be marketable.  If Tenant does not exercise
       its Right of First Offer and elect to lease space  available  in Phase II
       within the  prescribed  response  period,  the Right of First Offer shall
       terminate and the Landlord  shall be free to lease the space to anyone on
       any terms at any time during the Lease Term,  without any  obligation  to
       provide Tenant with a further right to lease that space.

       If Tenant timely and validly  exercises the Right of First Offer,  Tenant
       and Landlord shall  negotiate in good faith the terms of the lease on the
       Phase II space.  If Landlord  and Tenant  cannot agree as to the terms of
       the lease within twenty (20) days of Tenant's  written notice  exercising
       its Right of First  Offer,  Landlord  shall be free to lease the Phase II
       space to anyone on any terms it deems acceptable.

       E. Option to Extend  Term.  Provided  that Tenant is not in Default as of
       the time of  exercise  of this  option and the  commencement  date of the
       Option  Period,  and  provided  that as of such  date  there is no act or
       omission of Tenant that would  become a Default  with the passage of time
       or the giving of notice,  Tenant shall have one (1) successive  option to
       extend the Term of the Lease for the Premises in "as is" condition at the
       expiration of the original Lease Term for a period of five (5) years. All
       of the terms and  conditions  of this Lease  except for Base Rent and the
       provisions of this Paragraph shall be applicable to the Option Period.

       The Base Rent for the Premises under the option shall be the then current
       market  rent  for  comparable  facilities  in  the  proximate  South  San
       Francisco  market area.  The  definition of comparable  facilities  shall
       incorporate  the parking  amenities of the Premises,  and the  Building's
       location,  age,  quality,   amenities,   identity,  exterior  appearance,
       interior improvements, and type of construction, excluding laboratory and
       manufacturing improvements paid for by Tenant.

       Tenant shall give Landlord  written  notice of its intent to exercise its
       option at least twelve (12) but not more than  eighteen (18) months prior
       to the  expiration  of the then  current  Term for the  Premises.  Within
       fifteen (15) days after Tenant  exercises its option to extend,  Landlord
       shall provide  Tenant with the Base Rent, as determined by Landlord,  for
       the Option  Period.  The parties are obligated to negotiate in good faith
       to agree on the Base Rent. If the parties have not mutually agreed on the
       Base Rent within thirty (30) days from notification by Landlord to Tenant
       of Landlord's determination of Base Rent, each party hereto shall appoint
       one representative who shall be a licensed real estate broker experienced
       in the leasing of comparable facilities in the County of San Mateo to act
       as an arbitrator.  The two (2)  arbitrators so appointed  shall determine
       the Base Rent for the relevant Option Period.  The  determination of said
       Base Rent  shall be made by said two (2)  arbitrators  within  sixty (60)
       days from notification by Landlord to Tenant of Landlord's  determination
       of Base Rent and they shall  submit  said  determination  in writing  and
       signed by said arbitrators in duplicate. One of the written notifications
       shall be delivered to Landlord and the other to Tenant.

       In the event the two (2)  arbitrators  of the parties hereto cannot agree
       on the Base Rent for the Premises herein,  said two (2) arbitrators shall
       appoint a third  arbitrator  who shall be a licensed  real estate  broker
       experienced in the leasing of comparable  facilities in the County of San
       Mateo,  to act as an  arbitrator.  The Base Rent for the relevant  Option
       Period  shall  be   independently   determined   by  the  third  of  said
       arbitrators,  which said  determination  shall be made within ninety (90)
       days from notification by Landlord to Tenant of Landlord's  determination
       of  Base  Rent.  The  role  of the  third  arbitrator  shall  then  be to
       immediately select from the proposed  resolution of arbitrators #1 and #2
       the  one  that  most   closely   approximates   the  third   arbitrator's
       determination  of Base Rent. The third  arbitrator shall have no right to
       adopt a compromise or middle ground or any  modification of either of the
       two final proposed resolutions.  The resolution that the third arbitrator
       chooses as most closely  approximating his determination of the Base Rent
       shall  constitute the decision of all  arbitrators and shall be final and
       binding upon the parties.

                                       17
<PAGE>

       The parties hereto shall pay the charges of the  arbitrator  appointed by
       it and any expenses incurred by such arbitrator. The charges and expenses
       of the third arbitrator, as provided herein, shall be paid by the parties
       hereto in equal shares.

       In the event either  arbitrator  #1 or  arbitrator  #2 fails to present a
       Base  Rent  figure  within  the  thirty  (30) day  period,  the Base Rent
       presented by the other  arbitrator  shall be considered final and binding
       on both parties.

       Notwithstanding anything to the contrary herein contained, Tenant's right
       to  extend  the  term  by  exercise  of the  foregoing  Option  shall  be
       conditioned  upon the  following:  (I) at the time of the exercise of the
       Option,  and at the time of the commencement of the extended term, Tenant
       shall be in  possession  of and occupying the Premises for the conduct of
       its business  therein and the same shall not be occupied by any assignee,
       subtenant or licensee, and (ii) the notice of exercise shall constitute a
       representation  by Tenant  to  Landlord  effective  as of the date of the
       exercise and as of the date of  commencement  of the extended term,  that
       Tenant  does not  intend to seek to assign the lease in whole or in part,
       or sublet all of any portion of the Premises,  the election to extend the
       term being for purposes of utilizing  the Premises for Tenant's  purposes
       in the conduct of Tenant's business therein.

       F. Contingency.  This Lease is contingent upon the approval by Landlord's
       lenders.

       G.  Notice to Lender of  Default.  In the event  that a notice of default
       ("Notice of Default") is served on Landlord,  Tenant shall provide a copy
       of such  Notice of Default  to all  lenders  for whose  benefit a Deed of
       Trust then encumbers the Project (a "Beneficiary").  A copy of any Notice
       of Default should be mailed by certified mail to:

                           KeyBank National Association
                           10 West Market Street, 9th Floor
                           Indianapolis, IN  46266
                           Attn:  Jane E. Butler

       H.  Lender's  Time to Cure.  In the event  that  Tenant is served  with a
       Notice of Default and Landlord fails to cure such default within the time
       provided in this Lease,  Beneficiary shall have an additional thirty (30)
       days within which to cure the default, commencing with its receipt of the
       Notice of Default,  or if such default  cannot be cured within that time,
       then such  additional  time as may be  necessary  to effect  such cure if
       within  such  thirty  (30)  days the  Beneficiary  has  commenced  and is
       diligently   pursuing  the  remedies   necessary  to  cure  such  default
       (including,  but not limited to, commencement of foreclosure proceedings,
       if necessary to effect such cure).

                                       18
<PAGE>

     IN WITNESS WHEREOF, the parties hereto have executed this Lease the day and
     year first above written.

                         "Landlord"

                         TC NORTHERN CALIFORNIA, INC., a Delaware corporation

                         By: TC NORTHERN CALIFORNIA, INC.
                             ---------------------------------------------------

                         Its: Executive Vice President
                              --------------------------------------------------

                         By:
                             ---------------------------------------------------

                         Its:
                              --------------------------------------------------




                         "Tenant"

                         CELLEGY PHARMACEUTICALS, INC., a California corporation

                         By: /s/ K. Michael Forrest
                             ---------------------------------------------------

                         Its: President & CEO
                              --------------------------------------------------

                         By: /s/  A. Richard Juelis
                             ---------------------------------------------------

                         Its: V.P., Finance and CFO
                              --------------------------------------------------

<PAGE>

                                   EXHIBIT A-1

                          LEGAL DESCRIPTION OF PROJECT



  PARCEL I:

  BEGINNING  at granite  monument  set 10 chains  South of the corner  common to
  Sections  14-15-22  and 13 in Township 3 South of Range 5 West,  Mount  Diablo
  Base and Meridian; running thence along the line dividing said Sections 22 and
  23,  North 460.02 feet to the  Southwesterly  corner of tide Lot No. 8; thence
  along the Southerly line of said tide Lot 8, as same is described in Deed from
  Morgan Oyster Company, to Bay Counties Land Company,  dated March 25, 1909 and
  recorded in Book 163 of Deeds at page 44;  Records of San Mateo County,  South
  81(0) 45' East  339.24  feet;  North  64(0) 45' East  214.80  feet to a point;
  thence leaving said  Southerly line South 508.85 feet;  thence South 88(0) 27'
  14" West 229.94 feet;  thence  North 89(0) 59' West 300.16 feet;  thence North
  12.0 feet to the point of beginning.

  PARCEL II:

  A  non-exclusive  easement  for  storm  drainage  purposes  in on and over the
  following described property:

  That portion of the Easterly  12.50 feet of the Westerly  62.50 feet of Parcel
  "B" as described in the Lot Line Adjustment  recorded  September 1, 1992 under
  Document  Number  92141612 in the Records of San Mateo County,  also being the
  Westerly  12.50 feet of Parcel 1 as shown on the Map of Oyster Point  Business
  Park  recorded  April  12,  1982 in Book 52 of  Parcel  Maps at page 58 in the
  Records of San Mateo County that lies  Southerly of the line shown as "N 81(0)
  45' 55" W 339.24" on said Parcel Map (52 PM 58).

  The easement is  appurtenant to Parcel I above and was created by Easement for
  Storm Drainage dated July 31, 1997, by and between Shelton  Properties Inc., a
  Hawaii corporation and TC Northern California,  Inc., a Delaware  corporation,
  recorded August 1, 1997, Document No. 97093545, San Mateo County Records.

  PARCEL III:

  A  non-exclusive  easement  for grading and lateral  support for the  intended
  purpose and Grantee may import,  deposit grade, compact, and maintain soil and
  fill on the easement area, in on and over the following described property.

  A portion of Parcel "B" as described in the Lot Line Adjustment recorded under
  Series Number  92141612 in the Official  Records of said County,  described as
  follows:

  Beginning at the Southwesterly corner of Parcel "B" thence North 81(0) 45' 55"
  West along said line 44.44 feet to the actual point of  beginning  and through
  the following numbered courses:

  1)   South 81 degree  45' 55" East  along  the  Southerly  line of Parcel  "B"
       345.32 feet
  2)   North 64 degree  44' 05" East  along  the  Southerly  line of Parcel  "B"
       220.36 feet
  3)   North 30 degree 04' 12" West 10.04 feet
  4)   South 64 degree 44' 05" West 216.51 feet
  5)   North 81 degree 45' 55" West along said line 330.51 feet
  6)   South 57 degree57' 36" West 15.47 feet to the point of beginning.

  PARCEL IV:

  A  non-exclusive  easement  for grading and lateral  support for the  intended
  purpose and Grantee may, import,  deposit grade, compact and maintain soil and
  file on the easement area, in, on and over the following described property:

  A portion of the lands  described in the Lot Line  Adjustment  recorded  under
  Serial Number  92141612 in the Official  Records of said County,  described as
  follows:

  Beginning at the Southeasterly corner of Parcel A of said Lot Line Adjustment.
  This also being the  Southeasterly  corner of Parcel 4 of the Map  recorded in
  Volume 23 of Parcel  Maps at page 27 in the  records  of said  County;  thence
  North 00(0) 00' 55" West along the Westerly line of Parcel A 48.00 feet to the
  actual point of beginning and through the following numbered courses:

  1)   North  10(0) 07' 28" West  131.03  feet 2) North 05(0) 00' 57" West 80.31
       feet
  3)   North 02(0) 52' 40" West 40.05 feet
  4)   North  04(0)  50' 57" East  141.51  feet to a curve to the  right  with a
       radius of 30.00 feet
  5)   Along said curve  through a central of 53(0) 06' 39" an arc  distance  of
       27.81 feet to the Southerly line of Parcel B.
  6)   South 81(0) 45' 55" East along said line 6.08 feet to the  Easterly  line
       of Parcel A
  7)   South  00(0) 00' 55" East  along  said line  412.02  feet to the point of
       beginning.

  A.P. No.        015-190-020                              JPN 015 019 190 02 A
                                                           R/W 015 019 190 03
                                                           R/W 015 001 010 20.02

<PAGE>



                                   EXHIBIT A-2

                                    SITE PLAN

                                [GRAPHIC OMITTED]






                                    EXHIBIT


<PAGE>



                                   EXHIBIT A-3

                                  PHASE II PLAN

                                [GRAPHIC OMITTED]


                                    EXHIBIT


<PAGE>

                                   EXHIBIT B-1

                        INITIAL IMPROVEMENTS OF PREMISES



         1.       LANDLORD'S WORK

                  1.1 Landlord's  work  ("Landlord's  Work") shall be defined as
  the construction of the Building shell more particularly  described in Exhibit
  C, including ADA facilities,  to the extent required by the City. The scope of
  the shell construction  shall include:  The Building shell, roof, all exterior
  windows and doors, fire sprinklers at the roof line, utilities and services to
  the Building's exterior,  the parking lot, exterior common areas,  caulking of
  interior concrete joints and construction of interior stairs, and landscaping.

                  1.2  Landlord's  work shall be  completed  through  Landlord's
general  contractor,  South Bay Construction,  in compliance with all applicable
codes and regulations.

                  1.3  Landlord  shall  pay  for all  costs  involved  in  shell
construction described in Paragraph 1.1.

         2.       TENANT'S WORK

                  2.1 All interior improvements, including installation of Trade
  Fixtures,   as  indicated  in  Exhibit  B-3,  furnishings  and  building  core
  improvements  ("Building Core Improvements")  (collectively referred to herein
  as  "Tenant's  Work"),  shall be  constructed  by  Tenant at its sole cost and
  expense.  All of the plans  and  specifications  for  Tenant's  Work  shall be
  approved by Landlord in advance of commencing any construction.  Such approval
  by  Landlord,  shall not be  unreasonably  withheld.  The  parties  agree that
  certain  items of the Building  Core  Improvements  shall be completed  during
  shell construction by Landlord. Tenant shall invest a minimum of fifty dollars
  ($50.00)  per  rentable  square  foot,  in  excess of the  Tenant  Improvement
  Allowance  supplied by Landlord,  excluding soft costs ("Soft Costs" are those
  items  described in Paragraphs 2.2 (v) through  (xii)),  to improve the entire
  Premises.  Tenant  shall,  on or before the Term  Commencement  Date,  provide
  Landlord with an accounting,  certified by an officer of Tenant, itemizing all
  amounts  expended by Tenant in excess of the Tenant  Improvement  Allowance to
  improve  the  Premises.  If the amount  expended  by Tenant is less than fifty
  dollars ($50.00) per rentable square foot of the Building,  (exclusive of Soft
  Costs),  Tenant shall,  together with the  accounting,  deliver to Landlord an
  unconditional irrevocable letter of credit (separate from the Letter of Credit
  described in paragraph 19 of this Lease) in an amount equal to the  difference
  between the amount expended by Tenant and fifty dollars  ($50.00) per rentable
  square foot of the Building  (exclusive  of Soft Costs).  At any time prior to
  the  twenty-fourth  month of the Lease Term (but in no event  more  frequently
  than  monthly)  Tenant may provide  Landlord  with an amended  accounting,  as
  above,  showing  additional amounts expended by Tenant to improve the Premises
  since the last date  shown on the  immediately  preceding  accounting.  If the
  total  amount  expended  by Tenant is less than  fifty  dollars  ($50.00)  per
  rentable square foot of the Building  (exclusive of Soft Costs), the amount of
  the letter of credit may be reduced to a sum equal to the  difference  between
  the amount  expended by Tenant and fifty dollars  ($50.00) per rentable square
  foot of the Building  (exclusive of Soft Costs).  On or before the last day of
  the twenty-fourth month of the Lease Term, with an amended accounting as above
  showing in  addition  any amounts  expended by Tenant to improve the  Premises
  since the last date shown on  Tenant's  most recent  accounting,  if the total
  amount expended by Tenant is less than fifty dollars ($50) per rentable square
  foot,  Landlord shall be immediately  entitled to draw down from the letter of
  credit an amount equal to the difference between the amount expended by Tenant
  and fifty  dollars  ($50.00)  per  rentable  square  foot.  Upon such draw the
  requirement  that this letter of credit be  maintained  shall  terminate.  The
  letter of credit shall (a) designate Landlord or its assignees as beneficiary,
  (b) be issued by a financial institution approved by Landlord,  (c) be in form
  satisfactory to Landlord, and (d) be for a term of twenty-six months. Landlord
  shall not be required to deliver any  certifications  or  documentation of any
  kind to the  issuer in order to make a draw,  other  than  Landlord's  written
  demand.   The  issuer  shall  not  be  required  to  conduct  any  inquiry  or
  investigation  before  paying  Landlord  the  requested  amount  of the  draw.
  Landlord may assign,  transfer or pledge the letter of credit to any lender or
  purchaser in connection  with any financing or sale of the Premises.  Landlord
  shall provide to Tenant a Tenant  Improvement  Allowance of up to a maximum of
  thirty  dollars  ($30.00)  per rentable  square foot on the Premises  ("Tenant
  Improvement Allowance") which shall include Soft Costs. The Tenant Improvement
  Allowance  shall be reduced by the amount  Landlord  expends on Building  Core
  Improvements,  including the cost to Landlord of contracting with an architect
  to design the Building Core  Improvements.  Tenant shall promptly pay when due
  all costs for Tenant's Work. Landlord shall reimburse Tenant a portion of such
  costs not to exceed in the  aggregate  the  amount of the  Tenant  Improvement
  Allowance less amounts expended by Landlord for Building Core  Improvements as
  provided  above.   Tenant  shall,  not  more  frequently  than  monthly  after
  commencement of the construction of Tenant's Work, submit to Landlord requests
  for  reimbursement  of amounts  expended  by Tenant for  Tenant's  Work.  Each
  request shall be certified by an officer of Tenant and shall include,  without
  limitation,  (i) copies of all invoices paid by Tenant for which reimbursement
  is  sought  (ii)  proof of  payment  of each  invoice  (iii) a fully  executed
  unconditional   lien  release  from  each  payee,  and  (iv)  such  additional
  information  as Landlord may reasonably  request.  After Landlord has received
  and  approved  each request as provided  herein,  Landlord  shall  process the
  approved request for payment by its lender and upon disbursement by Landlord's
  Lender  reimburse  Tenant  promptly for  one-half of all amounts  shown in the
  request as expenditures  for costs to which the Tenant  Improvement  Allowance
  applies, as hereinbelow provided, up to the maximum amount set forth above.

                  2.2 Tenant's  Improvement  Allowance  (thirty dollars ($30.00)
  per rentable square foot on the Premises) shall be applied to, but not limited
  to the following costs:

                  (i)      Costs paid to general  contractors and subcontractors
                           for  labor,  material,  permits,  bonds  and the like
                           relating to the Premises;

                  (ii)     Construction management fee to Landlord in the amount
                           of  two  (2%)  percent  of  the  Tenant   Improvement
                           Allowance;

                  (iii)    Building  Core  Improvements  items such as  lobbies,
                           restrooms,  locker  areas  with  showers,  janitorial
                           room,  elevator  improvements  (i.e., pit,  footings,
                           shaft,  power,  etc.),  elevator  equipment  room and
                           structurally  reinforcing  the roof for Tenant's HVAC
                           and screening of mechanical equipment;

                  (iv)     Cost of  labor,  material  and  overhead  for  change
                           orders  approved by Landlord in accordance  with this
                           Exhibit B-1 and minor field changes;

                                    EXHIBIT

<PAGE>


                  (v)      Architectural, engineering and other design fees;

                  (vi)     Plans, drawings and printing costs;

                  (vii)    Insurance premiums;

                  (viii)   Cost of any reasonably  required reports,  surveys or
                           studies;

                  (ix)     The  cost of  utility  connections,  installation  of
                           utility  facilities and meters and user  installation
                           or hook-up fees;

                  (x)      All  governmental  fees and development  impact fees,
                           including  fees for  permits,  charges  and  costs of
                           obtaining governmental approvals;

                  (xi)     Recording costs and filing fees; and

                  (xii)    All other  costs  reasonably  incurred by Landlord in
                           connection   with   construction   of  Building  Core
                           Improvements,  provided that no compensation  will be
                           payable  for any  services  rendered  by  Landlord in
                           connection  with the  performance  of  Building  Core
                           Improvements,  except as expressly approved by Tenant
                           in accordance with Paragraph 2.2 (iii) above.

                  2.3 Tenant's  architect,  as described in Paragraph 2.4, shall
  furnish all  architectural  and engineering  plans and  specifications  ("Core
  Improvement  Plans  and  Specifications")  required  for the  construction  of
  Building Core  Improvements.  To the extent  Landlord's  architect  previously
  completed plans with regard to Core  Improvements,  Landlord's  architect will
  supply such plans to  Tenant's  architect  and the costs  incurred by Landlord
  will be deducted from Tenant's Improvement  Allowance.  Core Improvement Plans
  and Specifications shall be based on the Interior  Improvement  Specifications
  attached as Exhibit B-2 herein, or as otherwise  indicated by Landlord.  It is
  understood  and  agreed by Tenant  that any minor  changes  from any plans and
  specifications  that may be reasonably  necessary  during  construction of the
  Premises  shall not  affect,  change or  invalidate  this  Lease and shall not
  require Tenant's consent.

                  2.4  Tenant  shall  contract  with an  architect  approved  by
  Landlord for Tenant's Work (such approval shall not be  unreasonably  withheld
  by  Landlord) to furnish  architectural  plans and  specifications  ("Tenant's
  Plans and  Specifications")  required for the  construction  of Tenant's Work.
  Tenant's  Plans  and  Specifications  shall  also  be  based  on the  Interior
  Improvement Specifications attached hereto as Exhibit B-2.

                  2.5 Tenant shall contract with Landlord's  general  contractor
  for completion of Tenant's Work. Tenant's suppliers,  contractors, workmen and
  mechanics  shall be  subject  to  approval  by  Landlord,  which  shall not be
  unreasonably withheld or delayed,  prior to the commencement of work and shall
  be subject to Landlord's  administrative  control while performing their work.
  Landlord  shall  coordinate  with Tenant's  representative  the  scheduling of
  Tenant's Work. Prior to commencement of Landlord's  Work,  Tenant shall notify
  Landlord  with  respect to any special  scheduling  requirements  of Tenant in
  connection  with  the  installation  of  Tenant's  Work.  If at any  time  any
  supplier,  contractor, workman or mechanic performing Tenant's Work hinders or
  delays any other work in the  Building or performs  any work which may or does
  impair the quality,  integrity or  performance of any portion of the Building,
  Tenant  shall  take  all  steps  necessary  to  bring  an end to the  delay or
  hindrance,  and the contractor in question shall not recommence  Tenant's Work
  until reasonable steps have been taken to avoid further delay or hindrance. In
  performing  Tenant's Work, Tenant shall be required to employ contractors (and
  subcontractors)  which  (a)  are  parties  to,  and  bound  by,  a  collective
  bargaining  agreement with a labor  organization  affiliated with the Building
  and Construction  Trades Council of the AFL-CIO and (b) employ only members of
  such  labor   organizations   to  perform   work   within   their   respective
  jurisdictions),  with the  exception  of labor hired for  network  cabling for
  personal  and  mainframe  computer  systems and related  items.  Tenant  shall
  reimburse  Landlord for any repairs or  corrections  of Landlord's  Work or of
  Tenant's  Work or of any portion of the Building  caused by or resulting  from
  the work of any  supplier,  contractor,  workman or mechanic  with whom Tenant
  contracts.  Landlord shall provide access to Tenant's suppliers,  contractors,
  workmen and mechanics so as to achieve timely  completion and occupancy of the
  Premises.

                  2.6 Unless the Lease has been terminated pursuant to Paragraph
  26 of the Lease, upon the termination or expiration of the Lease, as such term
  may be extended, Tenant shall have the right to remove items listed in Exhibit
  B-3 which have been installed and paid for by Tenant.  Tenant shall repair any
  damage to the  Premises  resulting  from such  removal,  patch and  repair the
  walls, floor and ceiling and return the Premises in clean condition.  Landlord
  shall have a security  interest in Tenant's  Work pursuant to Paragraph 19. of
  the Lease.

         3.       COMPLETION DATES

                  3.1  Landlord  shall  notify  Tenant when  Landlord's  Work is
  sufficiently  underway that Tenant may begin  construction  of Tenant's  Work.
  Tenant  shall  notify  Landlord  in advance of the  approximate  date on which
  Tenant's Work will be  substantially  completed and will notify  Landlord when
  Tenant's Work is in fact substantially  competed  ("Substantial  Completion").
  The day Tenant  notifies  Landlord  that its work is  substantially  completed
  shall constitute the Term Commencement  Date. If any dispute shall arise as to
  whether  the  Premises  are  substantially  completed  and ready for  Tenant's
  occupancy, a certificate furnished by an independent architect mutually agreed
  to by Landlord and Tenant certifying the date of Substantial  Completion shall
  be conclusive.  The following shall constitute tenant delays ("Tenant Delays")
  under the Lease:

                           (a) Tenant's  failure to furnish  complete and timely
instructions or approvals;

                           (b)  Tenant's   failure  to  hire  an  architect  for
Building Core Improvements within fifteen (15) days of execution of Lease;

                           (c) Tenant's  failure to submit  conceptual plans for
Tenant's Work to Landlord within forty-five (45) days from execution of Lease;

                           (d) Tenant's failure to submit  preliminary Plans and
Specifications  for Tenant's Work for approval by Landlord  within  seventy-five
(75) days from execution of Lease;

                                    EXHIBIT


<PAGE>

                           (e)  Tenant's  failure  to enter into  contract  with
Landlord's  general  contractor for  construction of Tenant's Work within ninety
(90) days of execution of Lease;

                           (f) Tenant's failure to commence Tenant's Work within
fifteen (15) days of permission by Landlord;

                           (g)  Tenant's  failure  to   substantially   complete
construction  of Tenant's Work within one hundred  thirty-five  (135) days after
permission to commence construction of Tenant's Work by Landlord; and

                           (h)  Tenant's  failure  to deliver a  Certificate  of
Occupancy to Landlord  within thirty (30) days after  Substantial  Completion of
Tenant's Work.

  Tenant Delays  resulting in postponement of the Term  Commencement  Date shall
  cause  Tenant to be charged  rent under the terms of the Lease for each day of
  such delay.  All time periods  indicated above shall be computed on a calendar
  basis with no allowance for holidays, weekends or other customs.

                  3.2 Except as  otherwise  provided  in the  Lease,  failure of
  Landlord  to deliver  possession  of the  Premises  within the time and in the
  condition  provided  for in the  Lease  will not give  rise to any  claim  for
  damages by Tenant  against  Landlord  or  Landlord's  general  contractor.  If
  Landlord  fails to deliver the Premises in the condition as provided for under
  this Lease,  Landlord shall promptly correct any such deficiencies,  excluding
  any  immaterial  deficiencies  which do not  prevent  Tenant  from  using  the
  Premises  for  their   intended  use.  If  Landlord   fails  to  correct  such
  deficiencies  within a reasonable  time,  Tenant may pursue its legal remedies
  against Landlord.

                                    EXHIBIT


<PAGE>


                                   EXHIBIT B-2

                       INTERIOR IMPROVEMENT SPECIFICATIONS


  NOTE:  Not all specified items listed herein refer to this project.

1.       WALLS

         A.       All walls receive paint to be properly prepared. Texture to be
                  medium spray finish with 1 coat of latex paint to cover. Paint
                  to be Pittsburg Doric white.

         B.       Demising walls,  between tenant spaces to roof height shall be
                  metal  studs  with 5/8"  gypsum  board both  sides.  Fire tape
                  finish. U.O.N. See T.I. drawings for size, gauge and spacing.

         C.       Restroom  studs with 5/8"  gypsum  board to 6" above  adjacent
                  ceiling  U.O.N.  with  friction  fit  sound  batt  insulation.
                  Wainscot at wet walls to be +4' - 0' high with  ceramic  tile.
                  Texture to be smooth finish with semi-gloss latex paint U.O.N.

         D.       Interior  Office Walls.  Metal studs with 5/8" gypsum board on
                  both sides to underside of ceiling,  U.O.N.  Perimeter  office
                  walls between office and warehouse  areas to 6" above ceiling,
                  U.O.N. per Title 24 energy calculation requirements.

         E.       Other.  As may be directed by code or tenant purposes for fire
                  protection,  sound or energy  insulation,  demountability  and
                  aesthetics.

         F.       See tenant  improvements  drawings for specifications on size,
                  gauge and spacing of studs.

2.       CEILING

         A.       General.  Finished ceiling height to be 10'.

         B.       Restrooms.  Finished  ceiling height to be 9' with metal joist
                  with 5/8"  gypsum  board.  Texture  to be smooth  finish  with
                  semi-gloss   latex   paint  with   friction   fit  sound  batt
                  insulation. See tenant improvement drawings for specifications
                  on size, gauge and spacing of joists.

         C.       Office.  2' x 4' T-bar  suspended  ceiling system with 2' x 4'
                  Second  Look  II  acoustical  ceiling  tile  by  Armstrong  or
                  approved equal.

         D.       Other.  As may be  directed by tenant or as may  otherwise  be
                  required by tenant or codes. See tenant improvement drawings.

3.       FLOOR COVERING

         A.       Carpet - 30 oz. cut pile nylon  Design  Weave  "Westbridge"/26
                  oz. loop Design  Weave  "Caravan" or  equivalent  without pad.
                  Carpet to be glued down installation.  Color to be selected by
                  Tenant.

         B.       V.C.T. Armstrong "Standard Excelon" - 1/8" gauge: 12" x 12" or
                  approved equal.

         C.       Sheet vinyl Congoleum "Forever" or approved equal.

         D.       Base.  2-1/2" coved base at carpet and resilient floors.

         E.       Ceramic tile at toilet rooms with 6" ceramic tile base.

         F.       Sealed Concrete.  Sealed with a clear acrylic sealer.

4.       DOORS

         A.       Interior. SP Particleboard Core Oak 3'-0" x 7'-0", Rotary Sawn
                  Red Oak Veneer door by Weyerhauser  or equal.  20 minute rated
                  at one hour fire walls.  In laboratory and laboratory  support
                  spaces, hollow metal doors.

5.       FRAMES (DOORS & WINDOWS)

         A.       Timely Standard  prefinished steel door and sidelight frame in
                  standard white. "Timely II" at rated walls.

         B.       Other. As may be directed by code.

6.       HARDWARE

         A.       Latch set and lockset - Schlage D Series in brushed  stainless
                  steel with H.C. Levon lever.

         B.       Butts - 2 pair per door finished to match.

7.       RESTROOM ACCESSORIES

         A.       Water closet,  white  American  Standard  flush valve #2221.18
                  with Olsonite #95 seat and Sloan Ryal #110.3 flush valve. H.C.
                  stalls to have white  #9468.018  water closet with Sloan Royal
                  #115.3 flush valve.

         B.       Urinal,  white American  Standard  "Washbrook"  #6501.010 with
                  Sloan Royal #186 flush valve.

                                    EXHIBIT


<PAGE>

         C.       Lavatory,  American  Standard with faucet  #0355.027 and drain
                  #2103.786.

         D.       Recessed towel dispenser/waste receptacle, Bobrick #B3944.

         E.       Surface mounted seat cover dispenser, Bobrick.

         F.       Surface mounted toilet tissue dispenser, Bobrick #B2740.

         G.       Hook, Bobrick #B682.

         H.       Grab bars, Bobrick #B6806, 36" and 42".

         I.       Toilet partitions,  Bobrick 1080 series,  plastic laminate, or
                  equivalent. Baked enamel floor-braced with coat hook/bumper.

         J.       Urinal   partitions,   Bobrick  1085  "Duraline"   series,  or
                  equivalent.

         K.       Recessed  toilet room  accessories,  Brobrick B301,  B3570 and
                  B35704, or equivalent.


8.       HVAC

         Gas-fired roof-mounted VAV system for cooling, heating and ventilation.
         Designed and installed in accordance  with the California  Energy Act -
         Title 24.

                  1.       All cuts in roof to be properly  sealed,  flashed and
                           hot mopped.

9.       ELECTRICAL

         A.       Designed  and  installed  in  accordance  with the  California
                  Energy Act - Title 24.

         B.       Power   distributed  as  required  by  tenant  for  warehouse,
                  assembly and manufacturing equipment,  appliance operation and
                  special office machinery shall be ceiling hung U.O.N.

         C.       Warehouse/Manufacturing/Assembly   Lighting.   High   Bay  THS
                  150-watt  high pressure  sodium light  fixtures by Lithonia or
                  equal  in  areas  with  open   ceiling.   U.O.N.   See  tenant
                  improvement drawings.  T-bar dropped ceilings 2' x 4' recessed
                  mounted  fluorescent  fixtures with light levels  ranging from
                  15-75 foot candles as specified by Owner. Fixtures same as for
                  office lighting following.

         D.       Office  lighting  is  2' x  4'  recessed  mounted  fluorescent
                  ceiling  fixtures,  Lithonia  2PM4G B3 40 18LS  120 or  equal,
                  approved by Owner, with parabolic lens.

         E.       Downlights.  Halo #117-1CT-331-P Coilex Baffle 7" O.D. trim.

         F.       Wallwashers.  Halo #1176-T-425P  Coilex Baffle with scoop trim
                  7" O.D.

         G.       Track Lights.  Halo 120v single circuit power trac with Coilex
                  Continental lampholdes #L733P.1.

         H.       Wall-mounted fixture at restroom. Lithonia Wallens #W240-120A.

         I.       Other lighting as required by tenant or code.

         J.       Provide  plates for all power  outlets.  Provide pull wires at
                  all telephone and cable  (C.R.T.) pull  locations as indicated
                  on plan.

         K.       Illuminated exit signs as required by tenant or code.

         L.       Emergency lighting as required by code.

10.      FINISHES/SPECIALTIES

         A.       Special office wall or floor finishes.  See tenant improvement
                  drawings or specifications.

         B.       Lunch room,  conference room,  coffee or wet bar cabinetry and
                  plumbing. See tenant improvement drawings.

                                    EXHIBIT


<PAGE>

                                   EXHIBIT B-3

                       MOVEABLE EQUIPMENT & TRADE FIXTURES


         Moveable Equipment & Trade Fixtures includes:

                  Emergency Generator

                  Lab Benches and Counters

                  Fume Hoods

                  Cold Rooms

                  Mixing Tanks and Associated Equipment

                  Filling and Packing Machines

                  Autoclaves

                  Dishwashers

                  Chemical Storage Building


                                    EXHIBIT


<PAGE>


                                    EXHIBIT C

                          INITIAL PROJECT SPECIFICATION


GENERAL DESCRIPTION

      o   Two story concrete tilt-up building.

      o   Clear heights of 13'8" on the top floor and 24'2-1/2" and 19'2-1/2" on
          the bottom floor (349 and 347 Oyster Point respectively).

      o   Bay  spacing  of 33'-4"  and 34' x 60' on the top floor and 33'-4" and
          34' x 30' on the bottom (349 and 347 Oyster Point respectively).

BUILDING STRUCTURE

      o   All  foundations  to  Include  footings,  foundation  walls  or  other
          building foundation components required to support the entire building
          structure.

      o   Columns shall be steel box or pipe columns.

      o   All columns, beams, joists, purlins, headers, or other framing members
          to support the roof, roofing membrane and stair openings.

      o   Five inch (5") thick concrete slab on grade with #3  reinforcing  bars
          at  18"  on  center  each  way or  welded  wire  mesh  and  any  other
          reinforcing  or  structural  connections  that  may  be  necessary  or
          required.

      o   Two and a half (2-1/2")  thick concrete slab over metal deck supported
          by structural metal beams and columns.

      o   Exterior  walls that enclose the  perimeter of the building with steel
          reinforcing  and  structural  connections  that  may be  necessary  or
          required.

      o   All exterior glass and glazing with pained aluminum  frames.  Glass to
          be tinted as appropriate to the aesthetic design of the building.  All
          exterior doors,  door closer and locking devices  necessary for proper
          functioning.

      o   Hybrid Volcraft panel roof system to support roofing membrane.

      o   Four (4) ply built-up roofing  (including a base sheet, two plys and a
          cap sheet) and all  flashings by  Owens-Corning,  Johns  Manville,  or
          equal.

      o   Painting  of all  concrete  walls with  Tex-Coat  or Kel-Tex  textural
          paint.  All caulking of exterior  concrete  joint in  preparation  for
          painting.

      o   The foundation and structural  framing should be designed to support a
          minimum live load of 100 psf in all areas.

      o   The  floor-to-floor  height of the  building  shall allow a minimum of
          10'0" interior drop ceiling height.

      o   Roof hatch and ladder within each building.

      o   Floors to be smooth and level per industry  standards  for  comparable
          facility.

PLUMBING

      o   Underground  sanitary sewer laterals  connected to the city sewer main
          the street and piped into the building and under the concrete  slab on
          grade for the length of the building.  Sewer lines to consist of a six
          inch (6" sanitary  sewer line and a six inch (6") biowaste sewer line.
          Sanitary  sewer line under the slabs will be in a close  proximity  to
          the building restroom locations.

      o   Domestic  water mains  connected  to the city water main in the street
          and stubbed to the building.  Water main to the building  shall be two
          inches (2") in size with a three inch (3") supply line.

      o   Roof drain  leaders  piped and  connected  to the site storm  drainage
          systems or asphalt paved area.

      o   Gas lines  connected from the city public utility mains and gas meters
          adjacent to, and in close  proximity to the building.  Meters supplied
          by utility company.

ELECTRICAL

      o   All  primary  electrical  service  to the  building  that is  complete
          including  underground conduit and wire feeders from transformers pads
          into the building's  main switchgear  electrical  room. The electrical
          characteristics of the secondary side of transformers shall be 277/480
          volt,  3 Phase and the rated  capacity  of the  transformers  shall be
          2,000 amps for each building.

      o   Underground pull section,  meter, and panel(s),  for site lighting and
          landscaping.

                                    EXHIBIT


<PAGE>

      o   Underground  conduit  from the street to the  building  for  telephone
          trunk line service by Pacific Telephone. Conduit to the building shall
          not be less than 4".

      o   An electrically  operated  landscape  irrigation  controller that is a
          complete and functioning system.

      o   Underground  conduit  from the  building  to the main fire  protection
          system,  shut off valve  (PIV) for  installation  for  security  alarm
          wiring.

      o   All  parking  lot  and  landscaping   lighting  to  include  fixtures,
          underground  conduit,  wire,  distribution  panel and controller.  All
          exterior lighting shall be a complete and functioning system.

FIRE PROTECTION

      o   A complete and fully functional overhead system distributed throughout
          the  building  with a density of .2/3000 on the top floors and .4/2000
          and  .495/2000  on  the  bottom  floors  (349  and  347  Oyster  Point
          respectively).

      o   System  shall  include  all  sprinkler  heads that may be  required by
          building codes above the ceiling, when ceilings are installed.

LOADING

      o   Two (2) grade level 12' x 14' roll-up  doors plus at least one (1) 12'
          x 10' location for future grade level opening per building.

SITEWORK

      o   All work outside the building perimeter walls shall be considered site
          work  for the  building  shell  and  shall  include  grading,  asphalt
          concrete,   paving,   landscaping  (hard  and  soft),   landscape  and
          irrigation,  storm drainage, utility service laterals, curbs, butters,
          sidewalks,  specialty paving (if required),  retaining walls,  fencing
          and gates, trash enclosures, planters, sign monuments, parking lot and
          landscape lighting and other exterior lighting per code.

      o   Paving  sections for automobile and truck access shall be according to
          the Geological Soils Report.

      o   All parking lot striping to include handicap signage and spaces.

      o   Underground  site storm drainage system shall be connected to the city
          storm system main.

EXCLUSIONS

      o   The following items are not included in the building shell:

      o   All items relating to the elevator.

      o   Electrical panels and distribution.

      o   Screening of Mechanical equipment.

      o   HVAC including proof loading of roof structure.

      o   Security system.


                                    EXHIBIT


<PAGE>

                                    EXHIBIT D

                           TENANT ESTOPPEL CERTIFICATE


                  TO:               TC Northern California, Inc.
                                    1241 East Hillsdale Blvd., Ste. 200
                                    Foster City, CA  94404


  THIS IS TO CERTIFY:

     1. That the  undersigned  is the Tenant  under  that  certain  Lease  dated
___________________, and, if applicable,  amended  on__________________,  by and
between  _________________________________  ("Landlord"),  and  the  undersigned
("Tenant")  covering those certain premises located as shown on the drawing made
part of the Lease (the "Premises").

     2. That said  Lease is in full  force and  effect  and,  except as noted in
Paragraph 1. above,  has not been modified,  changed,  altered or amended in any
respect,  and is the only lease or agreement between the Tenant and the Landlord
affecting the Premises.

     3. To the best of Tenant's  knowledge,  the  information set forth below is
true and correct:

        (a)  Square footage of the Premises:  __________________________________
        (b)  Annual rent as of the Commencement of Lease: $_____________________
        (c)  Current annual rent (if different than at commencement): $_________
        (d)  Commencement date of Lease:  ______________________________________
        (e)  Lease termination date:  __________________________________________
        (f)  Rent paid to and including: _______________________________________
        (g)  Security deposit: $________________________________________________
        (h)  Prepaid rent for and in amount of: $_______________________________
        (i)  Free rent period:_________________________ to _____________________
        (j)  Amount of current monthly escrow payment  obligations
             with  respect to taxes,  insurance,  and Common  Area
             Maintenance charges under the Lease:

             Taxes:                                   $ ________________________
             Insurance:                               $ ________________________
             Common Area Maintenance Charges:         $ ________________________

        (k)  Dates  through  which Tenant has paid monthly  escrow
             payments and Common Area Maintenance charges:

             Escrow Payment for Taxes:          __________________________
             Escrow Payment for Insurance:      __________________________
             Common Area Maintenance Charges:   __________________________

     4. Delete if Tenant has not occupied the Premises:  Tenant now occupies the
Premises,  accepts the Premises in their current condition subject only to those
punch list items  listed in Exhibit A, if any, and is not aware of any defect in
the Premises except as described in Exhibit A, if any.

     5. Delete if Tenant has occupied the  Premises:  Tenant does not occupy the
Premises. The status of the plans and specifications for and the construction of
Tenant  Improvements  is  described  in Exhibit A. Tenant is  familiar  with the
Tenant  Improvement  work  done to date and is not  aware of any  defect in such
work, except as described in Exhibit A.

     6. No rent has been paid in the current  month other than as  disclosed  in
Paragraph 3. No free rent or other concessions,  benefits,  or inducements other
than as specified in the Lease have been granted to Tenant or  undertaken by the
Landlord.

     7. Tenant has not been granted any renewal, expansion,  purchase options or
any rights of first refusal, except as disclosed in writing in the Lease.

     8.  Neither  Tenant nor to the best of Tenant's  knowledge,  Landlord is in
breach of the Lease and there has not  occurred  any  event,  act,  omission  or
condition which by notice or lapse of time or both or otherwise,  will result in
any breach by Tenant or to the best of Tenant's  knowledge,  by Landlord.  As of
the date  hereof  and  except  as set forth in the  Lease,  the  undersigned  is
entitled  to no  credit,  offset  or  deduction  in  rent.  Tenant  knows  of no
liabilities or  obligations  of Landlord which have accrued but are  unsatisfied
under the Lease as of the date of this Certificate.

     9.  To the  best of  Tenant's  knowledge,  there  are no  actions,  whether
voluntary or otherwise,  pending  against the  undersigned  under the bankruptcy
laws or other laws for the  relief of debtors of the United  States or any state
thereof.

                                    EXHIBIT


<PAGE>

     10. With the  exception of this Lease and except as otherwise  disclosed in
writing to  Landlord,  neither the Tenant nor any  affiliate  of the Tenant is a
tenant under a lease or any other tenancy  arrangement  (i) with (a) __________;
(b)  __________;  (c)  ___________;  or (ii) involving any property in which the
entities named in clauses (___),  (___) or (___) are known by the Tenant to have
an ownership interest.



DATED this ______________ day of __________________, 19__.



                                              TENANT:
                                              
                                              CELLEGY PHARMACEUTICALS, INC.
                                              
                                              By:_______________________________
                                              
                                              Name:_____________________________
                                              Its:______________________________
                                    


           (Tenant to attach Exhibit A to Tenant Estoppel Certificate,
                        List of Defects, if necessary.)

                                    EXHIBIT


<PAGE>

                                    EXHIBIT E

                              RULES AND REGULATIONS
                           FOR TENANT'S CONTRACTOR(S)

     1.  Tenant's  contractor will be responsible for making  arrangements  with
         Landlord  as to time  for the use of  Building  and  equipment  such as
         elevators and loading areas.  The delivery of materials,  equipment and
         supplies to the Building or Premises must be coordinated  with Landlord
         at least two (2) business days prior to delivery.  The Building  debris
         box is not to be used for waste produced by Tenant's contractor.

     2.  Tenant's contractor shall not interfere with the Landlord's  contractor
         and sub-trades in any way and will cooperate fully with same.

     3.  All  Tenant's  contractor's  waste and debris must be removed  from the
         Premises and Building regularly and promptly. All combustible waste and
         debris  must be  stored in a  covered,  fire-proof  container  prior to
         removal.

     4.  Tenant's contractor and sub-trades shall take all precautions to ensure
         the  security  and the site  condition  of the Premises and Building in
         which the work is being performed, including their own tools, equipment
         and materials,  and are  responsible for any damage caused by employees
         and sub-trades to any part of the Building or Premises.

     5.  Tenant's  contractor shall remove and properly replace  underfloor duct
         access covers as required for Tenant's trades and services.  Any damage
         to underfloor  duct access  coverings  shall be repaired or replaced by
         Tenant's contractor to the satisfaction of Landlord.

     6.  Tenant's  contractor must provide their own fire protection  equipment,
         have same on premises at all times and conform to any  requirements  of
         Landlord or Landlord's contractor regarding fire protection.

     7.  Tenant's  contractor  shall carry out all work in  compliance  with all
         Federal,  State,  County and City Building Codes and  applicable  Acts,
         Ordinances and Statutes.

     8.  Tenant's  contractor shall provide all their own protective devices and
         coverings,  so as to protect the Building finishes provided by Landlord
         in the Building.

     9.  No  attachments  to or use  of  window  frames  and  mullions,  ceiling
         systems,  glass,  ceiling  frame or Building  frame,  will be permitted
         without the expressed written consent of Landlord.

     10. All Tenant's contractors,  employees and trades must be confined to the
         area in which work is being performed.

     11. Tenant or Tenant's contractor shall carry builder's risk insurance with
         limits of not less than the amount  requested  by  Landlord,  insurance
         covering loss or damage to the work during the course of  construction;
         worker's  compensation/employer's   liability  insurance  covering  all
         employees of contractor and subcontractor. All such policies shall name
         Landlord and Tenant as additional  insureds. A certificate of insurance
         must be provided to Landlord prior to commencement of work.

     12. Any construction, alteration, maintenance, repair, replacement, removal
         or decoration undertaken by Tenant's contractor shall be carried out in
         a good,  workmanlike,  and prompt manner,  shall comply with applicable
         statutes, laws, ordinances, regulations, rules, orders and requirements
         of the authorities having jurisdiction thereof, and shall be subject to
         supervision by Landlord or its employees,  agents, or contractors.  All
         construction  shall be performed in a timely manner  without  delays or
         interruptions.

     13. Tenant's  contractors shall not use excessive quantities of electricity
         or water  and  shall  not shut off any  water,  electricity,  sprinkler
         systems or other services  without first obtaining  Landlord's  express
         authorization.

                                    EXHIBIT



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